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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs34974961
log Bayes Factor = 19.694
Chromosome 3   position 53,853,009  (GRCh37) Explore rs34974961 on Ensembl!
Variant rs34974961 is part of Cluster X0045

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.998 0.002 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.998 0.002 0.000
Chapter II Neoplasms
0.997 0.003 0.000
Chapter XIV Diseases of the genitourinary system
0.997 0.003 0.000
D60-D64 Aplastic and other anaemias
0.996 0.004 0.000
Z30 Contraceptive management
0.995 0.005 0.000
D64 Other anaemias
0.995 0.005 0.000
Z30.2 Sterilisation
0.994 0.006 0.000
D64.9 Anaemia, unspecified
0.994 0.006 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.991 0.009 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.989 0.011 0.000
Chapter XX External causes of morbidity and mortality
0.989 0.011 0.000
E10-E14 Diabetes mellitus
0.987 0.013 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.985 0.015 0.000
I60-I69 Cerebrovascular diseases
0.983 0.017 0.000
Z03.8 Observation for other suspected diseases and conditions
0.981 0.019 0.000
E10 Insulin-dependent diabetes mellitus
0.976 0.024 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.975 0.025 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.972 0.028 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.968 0.032 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.968 0.032 0.000
R50-R69 General symptoms and signs
0.964 0.036 0.000
S60-S69 Injuries to the wrist and hand
0.959 0.041 0.000
I51 Complications and ill-defined descriptions of heart disease
0.958 0.042 0.000
R29.6 Tendency to fall, not elsewhere classified
0.954 0.046 0.000
E10.3 With ophthalmic complications
0.948 0.052 0.000
E70-E90 Metabolic disorders
0.946 0.054 0.000
R63 Symptoms and signs concerning food and fluid intake
0.942 0.058 0.000
N17-N19 Renal failure
0.940 0.060 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.938 0.062 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.937 0.063 0.000
N30-N39 Other diseases of urinary system
0.936 0.064 0.000
Z60 Problems related to social environment
0.933 0.067 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.927 0.073 0.000
S80-S89 Injuries to the knee and lower leg
0.926 0.074 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.926 0.074 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.921 0.079 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.921 0.079 0.000
N18 Chronic renal failure
0.916 0.084 0.000
Chapter I Certain infectious and parasitic diseases
0.910 0.090 0.000
Z60.2 Living alone
0.908 0.092 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.905 0.095 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.902 0.098 0.000
T81 Complications of procedures, not elsewhere classified
0.902 0.098 0.000
R25 Abnormal involuntary movements
0.902 0.098 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.901 0.099 0.000
R63.4 Abnormal weight loss
0.896 0.104 0.000
N20-N23 Urolithiasis
0.896 0.104 0.000
S00-S09 Injuries to the head
0.893 0.107 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.890 0.110 0.000
I51.7 Cardiomegaly
0.887 0.113 0.000
N60-N64 Disorders of breast
0.881 0.119 0.000
Chapter VI Diseases of the nervous system
0.880 0.120 0.000
S50-S59 Injuries to the elbow and forearm
0.879 0.121 0.000
I63 Cerebral infarction
0.879 0.121 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.879 0.121 0.000
R52 Pain, not elsewhere classified
0.875 0.125 0.000
C44 Other malignant neoplasms of skin
0.874 0.126 0.000
I42 Cardiomyopathy
0.873 0.127 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.873 0.127 0.000
Z36 Antenatal screening
0.873 0.127 0.000
N32 Other disorders of bladder
0.870 0.130 0.000
R07 Pain in throat and chest
0.868 0.132 0.000
I35 Nonrheumatic aortic valve disorders
0.866 0.134 0.000
I44 Atrioventricular and left bundle-branch block
0.863 0.137 0.000
S82 Fracture of lower leg, including ankle
0.861 0.139 0.000
E20-E35 Disorders of other endocrine glands
0.860 0.140 0.000
R00 Abnormalities of heart beat
0.860 0.140 0.000
C79 Secondary malignant neoplasm of other sites
0.858 0.142 0.000
I69 Sequelae of cerebrovascular disease
0.858 0.142 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.857 0.143 0.000
I50 Heart failure
0.854 0.146 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.852 0.148 0.000
N18.3 Chronic kidney disease, stage 3
0.850 0.150 0.000
E89.0 Postprocedural hypothyroidism
0.850 0.150 0.000
I46 Cardiac arrest
0.849 0.151 0.000
Y52 Agents primarily affecting the cardiovascular system
0.847 0.153 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.846 0.153 0.000
C44.4 Skin of scalp and neck
0.845 0.155 0.000
N20 Calculus of kidney and ureter
0.843 0.157 0.000
Y45.0 Opioids and related analgesics
0.843 0.157 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.842 0.158 0.000
T86 Failure and rejection of transplanted organs and tissues
0.840 0.160 0.000
I51.8 Other ill-defined heart diseases
0.837 0.163 0.000
Chapter VIII Diseases of the ear and mastoid process
0.834 0.166 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.834 0.166 0.000
E83 Disorders of mineral metabolism
0.831 0.169 0.000
R63.0 Anorexia
0.829 0.171 0.000
R60 Oedema, not elsewhere classified
0.827 0.173 0.000
E10.1 With ketoacidosis
0.826 0.174 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.826 0.174 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.824 0.176 0.000
D80-D89 Certain disorders involving the immune mechanism
0.823 0.177 0.000
R00.1 Bradycardia, unspecified
0.822 0.178 0.000
N10-N16 Renal tubulo-interstitial diseases
0.820 0.180 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.816 0.184 0.000
I62 Other nontraumatic intracranial haemorrhage
0.816 0.184 0.000
S62 Fracture at wrist and hand level
0.815 0.185 0.000
S00 Superficial injury of head
0.814 0.186 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.814 0.186 0.000
C44.3 Skin of other and unspecified parts of face
0.814 0.186 0.000
R25.1 Tremor, unspecified
0.812 0.188 0.000
E11 Non-insulin-dependent diabetes mellitus
0.812 0.188 0.000
S61 Open wound of wrist and hand
0.811 0.189 0.000
R07.2 Precordial pain
0.809 0.191 0.000
Chapter VII Diseases of the eye and adnexa
0.808 0.192 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.808 0.192 0.000
S90-S99 Injuries to the ankle and foot
0.807 0.193 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.805 0.195 0.000
N30 Cystitis
0.804 0.196 0.000
R40 Somnolence, stupor and coma
0.804 0.196 0.000
I67 Other cerebrovascular diseases
0.804 0.196 0.000
S82.8 Fractures of other parts of lower leg
0.800 0.200 0.000
C15-C26 Malignant neoplasms of digestive organs
0.799 0.201 0.000
I42.0 Dilated cardiomyopathy
0.795 0.204 0.000
R94 Abnormal results of function studies
0.795 0.205 0.000
D62 Acute posthaemorrhagic anaemia
0.794 0.206 0.000
W00-W19 Falls
0.791 0.209 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.791 0.209 0.000
Y40 Systemic antibiotics
0.790 0.210 0.000
Z02 Examination and encounter for administrative purposes
0.790 0.210 0.000
E10.4 With neurological complications
0.787 0.213 0.000
N00-N08 Glomerular diseases
0.785 0.215 0.000
S64 Injury of nerves at wrist and hand level
0.784 0.216 0.000
I44.7 Left bundle-branch block, unspecified
0.784 0.216 0.000
C34 Malignant neoplasm of bronchus and lung
0.783 0.217 0.000
R54 Senility
0.783 0.217 0.000
I38 Endocarditis, valve unspecified
0.782 0.218 0.000
I31 Other diseases of pericardium
0.782 0.218 0.000
I63.8 Other cerebral infarction
0.782 0.218 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.779 0.221 0.000
Y43 Primarily systemic agents
0.777 0.223 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.776 0.224 0.000
N61 Inflammatory disorders of breast
0.776 0.224 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.775 0.225 0.000
E10.9 Without complications
0.775 0.225 0.000
Y44 Agents primarily affecting blood constituents
0.773 0.226 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.773 0.227 0.000
N25-N29 Other disorders of kidney and ureter
0.772 0.228 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.769 0.231 0.000
R07.4 Chest pain, unspecified
0.768 0.232 0.000
Z03.1 Observation for suspected malignant neoplasm
0.768 0.232 0.000
N32.8 Other specified disorders of bladder
0.768 0.232 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.768 0.232 0.000
C80 Malignant neoplasm without specification of site
0.767 0.233 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.766 0.234 0.000
S60 Superficial injury of wrist and hand
0.766 0.234 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.764 0.236 0.000
S20-S29 Injuries to the thorax
0.763 0.237 0.000
N18.0 End-stage renal disease
0.762 0.238 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.762 0.238 0.000
I34 Nonrheumatic mitral valve disorders
0.760 0.240 0.000
C43 Malignant melanoma of skin
0.759 0.241 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.757 0.243 0.000
N18.9 Chronic renal failure, unspecified
0.756 0.244 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.756 0.244 0.000
D10-D36 Benign neoplasms
0.755 0.245 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.753 0.247 0.000
I49 Other cardiac arrhythmias
0.753 0.247 0.000
Z63 Other problems related to primary support group, including family circumstances
0.751 0.249 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.749 0.251 0.000
E40-E46 Malnutrition
0.749 0.251 0.000
B25-B34 Other viral diseases
0.748 0.252 0.000
H80-H83 Diseases of inner ear
0.747 0.253 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.746 0.253 0.000
V80-V89 Other land transport accidents
0.746 0.254 0.000
N99-N99 Other disorders of the genitourinary system
0.745 0.254 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.745 0.255 0.000
D61 Other aplastic anaemias
0.745 0.255 0.000
I73 Other peripheral vascular diseases
0.745 0.255 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.744 0.255 0.000
N13 Obstructive and reflux uropathy
0.743 0.257 0.000
I50.9 Heart failure, unspecified
0.741 0.259 0.000
Z57 Occupational exposure to risk-factors
0.739 0.261 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.739 0.261 0.000
A80-A89 Viral infections of the central nervous system
0.739 0.261 0.000
E11.3 With ophthalmic complications
0.737 0.263 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.737 0.263 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.737 0.263 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.737 0.263 0.000
Z36.9 Antenatal screening, unspecified
0.736 0.264 0.000
E87.2 Acidosis
0.735 0.265 0.000
S52 Fracture of forearm
0.735 0.265 0.000
N20.0 Calculus of kidney
0.733 0.267 0.000
R52.2 Other chronic pain
0.733 0.267 0.000
Z35 Supervision of high-risk pregnancy
0.733 0.267 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.733 0.267 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.732 0.268 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.732 0.268 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.732 0.268 0.000
Z33 Pregnant state, incidental
0.731 0.269 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.730 0.270 0.000
C44.1 Skin of eyelid, including canthus
0.730 0.270 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.729 0.270 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.729 0.271 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.728 0.272 0.000
D00-D09 In situ neoplasms
0.727 0.273 0.000
R57 Shock, not elsewhere classified
0.726 0.274 0.000
R25.2 Cramp and spasm
0.726 0.274 0.000
R52.9 Pain, unspecified
0.725 0.275 0.000
I72 Other aneurysm
0.725 0.275 0.000
W20-W49 Exposure to inanimate mechanical forces
0.725 0.275 0.000
R60.0 Localised oedema
0.724 0.276 0.000
H40-H42 Glaucoma
0.724 0.276 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.723 0.276 0.000
I44.1 Atrioventricular block, second degree
0.723 0.277 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.723 0.277 0.000
R30-R39 Symptoms and signs involving the urinary system
0.723 0.277 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.721 0.279 0.000
R40.0 Somnolence
0.721 0.279 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.719 0.281 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.719 0.281 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.718 0.282 0.000
E50-E64 Other nutritional deficiencies
0.718 0.282 0.000
N18.2 Chronic kidney disease, stage 2
0.718 0.282 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.718 0.282 0.000
V10-V19 Pedal cyclist injured in transport accident
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
C50-C50 Malignant neoplasm of breast
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I36 Nonrheumatic tricuspid valve disorders
0.716 0.284 0.000
I33 Acute and subacute endocarditis
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
I30 Acute pericarditis
0.716 0.284 0.000
I26 Pulmonary embolism
0.716 0.284 0.000
D55-D59 Haemolytic anaemias
0.715 0.284 0.000
Z39 Postpartum care and examination
0.715 0.285 0.000
Z38 Liveborn infants according to place of birth
0.715 0.285 0.000
Z32 Pregnancy examination and test
0.715 0.285 0.000
Z31 Procreative management
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.715 0.285 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.714 0.285 0.000
A30-A49 Other bacterial diseases
0.715 0.285 0.000
B35-B49 Mycoses
0.714 0.285 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.714 0.286 0.000
E27 Other disorders of adrenal gland
0.714 0.286 0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device
0.714 0.286 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.714 0.286 0.000
Z30.9 Contraceptive management, unspecified
0.713 0.286 0.000
Z30.8 Other contraceptive management
0.713 0.286 0.000
Z30.4 Surveillance of contraceptive drugs
0.713 0.286 0.000
Z30.3 Menstrual extraction
0.713 0.286 0.000
Z30.0 General counselling and advice on contraception
0.713 0.286 0.000
D64.8 Other specified anaemias
0.713 0.287 0.000
D64.4 Congenital dyserythropoietic anaemia
0.713 0.287 0.000
D64.3 Other sideroblastic anaemias
0.713 0.287 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.713 0.287 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.713 0.287 0.000
D64.0 Hereditary sideroblastic anaemia
0.713 0.287 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.713 0.287 0.000
Y45.1 Salicylates
0.712 0.288 0.000
I46.0 Cardiac arrest with successful resuscitation
0.712 0.288 0.000
H30-H36 Disorders of choroid and retina
0.711 0.289 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.710 0.290 0.000
Z10 Routine general health check-up of defined subpopulation
0.710 0.290 0.000
R27 Other lack of coordination
0.709 0.291 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.709 0.291 0.000
Y35-Y36 Legal intervention and operations of war
0.709 0.291 0.000
Y10-Y34 Event of undetermined intent
0.709 0.291 0.000
Y00-Y09 Assault
0.709 0.291 0.000
X85-X99 Assault
0.709 0.291 0.000
X60-X84 Intentional self-harm
0.709 0.291 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.709 0.291 0.000
X50-X57 Overexertion, travel and privation
0.709 0.291 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.709 0.291 0.000
X30-X39 Exposure to forces of nature
0.709 0.291 0.000
X20-X29 Contact with venomous animals and plants
0.709 0.291 0.000
X10-X19 Contact with heat and hot substances
0.709 0.291 0.000
X00-X09 Exposure to smoke, fire and flames
0.709 0.291 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.709 0.291 0.000
W75-W84 Other accidental threats to breathing
0.709 0.291 0.000
W65-W74 Accidental drowning and submersion
0.709 0.291 0.000
W50-W64 Exposure to animate mechanical forces
0.709 0.291 0.000
V98-V99 Other and unspecified transport accidents
0.709 0.291 0.000
V95-V97 Air and space transport accidents
0.709 0.291 0.000
V90-V94 Water transport accidents
0.709 0.291 0.000
V70-V79 Bus occupant injured in transport accident
0.709 0.291 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.709 0.291 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.709 0.291 0.000
V40-V49 Car occupant injured in transport accident
0.709 0.291 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.709 0.291 0.000
V20-V29 Motorcycle rider injured in transport accident
0.709 0.291 0.000
V01-V09 Pedestrian injured in transport accident
0.709 0.291 0.000
N20.1 Calculus of ureter
0.709 0.291 0.000
Y57 Other and unspecified drugs and medicaments
0.708 0.292 0.000
D86 Sarcoidosis
0.708 0.292 0.000
C51-C58 Malignant neoplasms of female genital organs
0.708 0.292 0.000
E13 Other specified diabetes mellitus
0.708 0.292 0.000
E12 Malnutrition-related diabetes mellitus
0.708 0.292 0.000
Z03.4 Observation for suspected myocardial infarction
0.707 0.293 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.706 0.294 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.706 0.294 0.000
Z03.0 Observation for suspected tuberculosis
0.706 0.294 0.000
Z04 Examination and observation for other reasons
0.706 0.294 0.000
R61 Hyperhidrosis
0.706 0.294 0.000
N32.3 Diverticulum of bladder
0.705 0.295 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.705 0.295 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.705 0.295 0.000
I61 Intracerebral haemorrhage
0.705 0.295 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.705 0.295 0.000
N32.9 Bladder disorder, unspecified
0.704 0.296 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.704 0.296 0.000
I51.9 Heart disease, unspecified
0.703 0.296 0.000
I78 Diseases of capillaries
0.702 0.298 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.701 0.299 0.000
S61.0 Open wound of finger(s) without damage to nail
0.700 0.300 0.000
E10.8 With unspecified complications
0.700 0.300 0.000
E10.7 With multiple complications
0.700 0.300 0.000
E10.6 With other specified complications
0.700 0.300 0.000
E10.5 With peripheral circulatory complications
0.700 0.300 0.000
E10.2 With renal complications
0.700 0.300 0.000
E10.0 With coma
0.700 0.300 0.000
S51 Open wound of forearm
0.699 0.301 0.000
T87 Complications peculiar to reattachment and amputation
0.699 0.301 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.699 0.301 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.698 0.302 0.000
N20.2 Calculus of kidney with calculus of ureter
0.697 0.303 0.000
Y59 Other and unspecified vaccines and biological substances
0.697 0.303 0.000
Y58 Bacterial vaccines
0.697 0.303 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.697 0.303 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.697 0.303 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.697 0.303 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.697 0.303 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.697 0.303 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.697 0.303 0.000
Y48 Anaesthetics and therapeutic gases
0.697 0.303 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.697 0.303 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.697 0.303 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.697 0.303 0.000
N64 Other disorders of breast
0.696 0.304 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.695 0.305 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.695 0.305 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.695 0.305 0.000
N30.2 Other chronic cystitis
0.695 0.305 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.695 0.305 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.695 0.305 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.694 0.306 0.000
R29.4 Clicking hip
0.694 0.306 0.000
R29.3 Abnormal posture
0.694 0.306 0.000
R29.2 Abnormal reflex
0.694 0.306 0.000
R29.1 Meningismus
0.694 0.306 0.000
R29.0 Tetany
0.694 0.306 0.000
Z65 Problems related to other psychosocial circumstances
0.694 0.306 0.000
Z64 Problems related to certain psychosocial circumstances
0.694 0.306 0.000
Z62 Other problems related to upbringing
0.694 0.306 0.000
Z61 Problems related to negative life events in childhood
0.694 0.306 0.000
Z59 Problems related to housing and economic circumstances
0.694 0.306 0.000
Z58 Problems related to physical environment
0.694 0.306 0.000
Z56 Problems related to employment and unemployment
0.694 0.306 0.000
Z55 Problems related to education and literacy
0.694 0.306 0.000
T86.1 Kidney transplant failure and rejection
0.694 0.306 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.693 0.306 0.000
G20-G26 Extrapyramidal and movement disorders
0.693 0.307 0.000
R68 Other general symptoms and signs
0.691 0.308 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.691 0.308 0.000
R62 Lack of expected normal physiological development
0.691 0.308 0.000
R64 Cachexia
0.691 0.308 0.000
R58 Haemorrhage, not elsewhere classified
0.691 0.308 0.000
S81 Open wound of lower leg
0.691 0.309 0.000
S70-S79 Injuries to the hip and thigh
0.690 0.310 0.000
C15 Malignant neoplasm of oesophagus
0.690 0.310 0.000
D23 Other benign neoplasms of skin
0.689 0.311 0.000
R03.1 Nonspecific low blood-pressure reading
0.688 0.312 0.000
S69 Other and unspecified injuries of wrist and hand
0.687 0.313 0.000
S67 Crushing injury of wrist and hand
0.687 0.313 0.000
S65 Injury of blood vessels at wrist and hand level
0.687 0.313 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.687 0.313 0.000
N60 Benign mammary dysplasia
0.687 0.313 0.000
I51.6 Cardiovascular disease, unspecified
0.687 0.313 0.000
I51.5 Myocardial degeneration
0.687 0.313 0.000
I51.4 Myocarditis, unspecified
0.687 0.313 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.687 0.313 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.687 0.313 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.687 0.313 0.000
I51.0 Cardiac septal defect, acquired
0.687 0.313 0.000
E83.1 Disorders of iron metabolism
0.685 0.315 0.000
S82.6 Fracture of lateral malleolus
0.685 0.315 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.683 0.317 0.000
R94.5 Abnormal results of liver function studies
0.683 0.317 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.683 0.317 0.000
T66-T78 Other and unspecified effects of external causes
0.682 0.318 0.000
R41.0 Disorientation, unspecified
0.681 0.319 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.681 0.319 0.000
N63 Unspecified lump in breast
0.681 0.319 0.000
C34.3 Lower lobe, bronchus or lung
0.680 0.320 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.679 0.320 0.000
H36 Retinal disorders in diseases classified elsewhere
0.680 0.320 0.000
S62.6 Fracture of other finger
0.679 0.321 0.000
E88 Other metabolic disorders
0.679 0.321 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.679 0.321 0.000
I74 Arterial embolism and thrombosis
0.678 0.322 0.000
N39 Other disorders of urinary system
0.678 0.322 0.000
E85 Amyloidosis
0.678 0.322 0.000
E84 Cystic fibrosis
0.678 0.322 0.000
E79 Disorders of purine and pyrimidine metabolism
0.678 0.322 0.000
E77 Disorders of glycoprotein metabolism
0.678 0.322 0.000
E76 Disorders of glycosaminoglycan metabolism
0.678 0.322 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.678 0.322 0.000
E74 Other disorders of carbohydrate metabolism
0.678 0.322 0.000
E73 Lactose intolerance
0.678 0.322 0.000
E72 Other disorders of amino-acid metabolism
0.678 0.322 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.678 0.322 0.000
E70 Disorders of aromatic amino-acid metabolism
0.678 0.322 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.678 0.322 0.000
G40-G47 Episodic and paroxysmal disorders
0.677 0.322 0.000
E23 Hypofunction and other disorders of pituitary gland
0.677 0.323 0.000
R52.0 Acute pain
0.676 0.324 0.000
R55 Syncope and collapse
0.676 0.324 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.676 0.324 0.000
R63.5 Abnormal weight gain
0.676 0.324 0.000
R63.3 Feeding difficulties and mismanagement
0.676 0.324 0.000
R63.2 Polyphagia
0.676 0.324 0.000
R63.1 Polydipsia
0.676 0.324 0.000
S50 Superficial injury of forearm
0.674 0.326 0.000
S01 Open wound of head
0.674 0.326 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.673 0.327 0.000
M80-M85 Disorders of bone density and structure
0.673 0.327 0.000
I70 Atherosclerosis
0.671 0.329 0.000
N37 Urethral disorders in diseases classified elsewhere
0.671 0.329 0.000
N34 Urethritis and urethral syndrome
0.671 0.329 0.000
N33 Bladder disorders in diseases classified elsewhere
0.671 0.329 0.000
I50.1 Left ventricular failure
0.671 0.329 0.000
D50-D53 Nutritional anaemias
0.670 0.330 0.000
N18.5 Chronic kidney disease, stage 5
0.670 0.330 0.000
E00-E07 Disorders of thyroid gland
0.670 0.330 0.000
S00.8 Superficial injury of other parts of head
0.670 0.330 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.670 0.330 0.000
Z60.9 Problem related to social environment, unspecified
0.669 0.331 0.000
Z60.8 Other problems related to social environment
0.669 0.331 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.669 0.331 0.000
Z60.4 Social exclusion and rejection
0.669 0.331 0.000
Z60.3 Acculturation difficulty
0.669 0.331 0.000
Z60.1 Atypical parenting situation
0.669 0.331 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.669 0.331 0.000
O60-O75 Complications of labour and delivery
0.669 0.331 0.000
R07.1 Chest pain on breathing
0.669 0.331 0.000
R00.2 Palpitations
0.668 0.332 0.000
I35.1 Aortic (valve) insufficiency
0.668 0.332 0.000
I77 Other disorders of arteries and arterioles
0.668 0.332 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.667 0.332 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.667 0.333 0.000
I35.0 Aortic (valve) stenosis
0.667 0.333 0.000
M50-M54 Other dorsopathies
0.667 0.333 0.000
R06 Abnormalities of breathing
0.666 0.334 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.665 0.335 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.665 0.335 0.000
Z36.8 Other antenatal screening
0.665 0.335 0.000
S89 Other and unspecified injuries of lower leg
0.664 0.336 0.000
S88 Traumatic amputation of lower leg
0.664 0.336 0.000
S87 Crushing injury of lower leg
0.664 0.336 0.000
S86 Injury of muscle and tendon at lower leg level
0.664 0.336 0.000
S85 Injury of blood vessels at lower leg level
0.664 0.336 0.000
S84 Injury of nerves at lower leg level
0.664 0.336 0.000
Z09.7 Follow-up examination after combined treatment for other conditions
0.664 0.336 0.000
Z09.4 Follow-up examination after treatment of fracture
0.664 0.336 0.000
Z09.3 Follow-up examination after psychotherapy
0.664 0.336 0.000
Z09.1 Follow-up examination after radiotherapy for other conditions
0.664 0.336 0.000
Z34 Supervision of normal pregnancy
0.663 0.336 0.000
H40 Glaucoma
0.664 0.336 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.663 0.337 0.000
E83.3 Disorders of phosphorus metabolism
0.663 0.337 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.661 0.338 0.000
M45-M49 Spondylopathies
0.661 0.339 0.000
I46.9 Cardiac arrest, unspecified
0.661 0.339 0.000
S61.8 Open wound of other parts of wrist and hand
0.661 0.339 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.661 0.339 0.000
S00.0 Superficial injury of scalp
0.661 0.339 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.661 0.339 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.660 0.340 0.000
E83.4 Disorders of magnesium metabolism
0.660 0.340 0.000
R46 Symptoms and signs involving appearance and behaviour
0.660 0.340 0.000
R43 Disturbances of smell and taste
0.660 0.340 0.000
A00-A09 Intestinal infectious diseases
0.660 0.340 0.000
R45 Symptoms and signs involving emotional state
0.660 0.340 0.000
N18.4 Chronic kidney disease, stage 4
0.659 0.340 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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