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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs35060747
log Bayes Factor = 18.5543
Chromosome 5   position 117,671,831  (GRCh37) Explore rs35060747 on Ensembl!
Variant rs35060747 is part of Cluster X0093

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
M80-M85 Disorders of bone density and structure
0.997 0.003 0.000
Chapter V Mental and behavioural disorders
0.996 0.004 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.994 0.006 0.000
M81 Osteoporosis without pathological fracture
0.993 0.007 0.000
M81.9 Osteoporosis, unspecified
0.991 0.009 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.988 0.012 0.000
Chapter II Neoplasms
0.980 0.020 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.978 0.022 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.976 0.024 0.000
I42 Cardiomyopathy
0.976 0.024 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.974 0.026 0.000
S50-S59 Injuries to the elbow and forearm
0.973 0.027 0.000
Chapter VI Diseases of the nervous system
0.972 0.028 0.000
F30-F39 Mood [affective] disorders
0.969 0.031 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.968 0.032 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.964 0.036 0.000
I20-I25 Ischaemic heart diseases
0.964 0.036 0.000
Chapter XX External causes of morbidity and mortality
0.961 0.039 0.000
M65-M68 Disorders of synovium and tendon
0.960 0.040 0.000
S00-S09 Injuries to the head
0.953 0.047 0.000
S52 Fracture of forearm
0.948 0.052 0.000
T51 Toxic effect of alcohol
0.941 0.059 0.000
M70-M79 Other soft tissue disorders
0.941 0.059 0.000
I21 Acute myocardial infarction
0.939 0.061 0.000
S60-S69 Injuries to the wrist and hand
0.938 0.062 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.938 0.062 0.000
F32 Depressive episode
0.933 0.067 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.932 0.068 0.000
S52.5 Fracture of lower end of radius
0.931 0.069 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.927 0.073 0.000
S52.50 Fracture of lower end of radius (closed)
0.919 0.081 0.000
D00-D09 In situ neoplasms
0.919 0.081 0.000
E70-E90 Metabolic disorders
0.916 0.084 0.000
I34 Nonrheumatic mitral valve disorders
0.914 0.086 0.000
S80-S89 Injuries to the knee and lower leg
0.913 0.087 0.000
E20-E35 Disorders of other endocrine glands
0.912 0.088 0.000
T51.0 Ethanol
0.910 0.090 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.910 0.090 0.000
I42.0 Dilated cardiomyopathy
0.909 0.091 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.905 0.095 0.000
C15-C26 Malignant neoplasms of digestive organs
0.904 0.096 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.904 0.096 0.000
G90-G99 Other disorders of the nervous system
0.901 0.099 0.000
M86-M90 Other osteopathies
0.900 0.100 0.000
S00 Superficial injury of head
0.898 0.102 0.000
Chapter X Diseases of the respiratory system
0.893 0.107 0.000
T86 Failure and rejection of transplanted organs and tissues
0.891 0.109 0.000
I51 Complications and ill-defined descriptions of heart disease
0.891 0.109 0.000
D50-D53 Nutritional anaemias
0.888 0.112 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.887 0.113 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.885 0.115 0.000
Chapter XXII Codes for special purposes
0.885 0.115 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.880 0.120 0.000
G20-G26 Extrapyramidal and movement disorders
0.876 0.123 0.000
I60-I69 Cerebrovascular diseases
0.874 0.126 0.000
M65 Synovitis and tenosynovitis
0.873 0.127 0.000
M67 Other disorders of synovium and tendon
0.872 0.128 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.872 0.128 0.000
S00.8 Superficial injury of other parts of head
0.872 0.128 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.870 0.130 0.000
I31 Other diseases of pericardium
0.869 0.131 0.000
F32.9 Depressive episode, unspecified
0.867 0.133 0.000
I34.0 Mitral (valve) insufficiency
0.862 0.138 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.860 0.140 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.858 0.142 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.857 0.143 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.855 0.145 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.852 0.148 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.850 0.150 0.000
C71 Malignant neoplasm of brain
0.850 0.150 0.000
I10-I15 Hypertensive diseases
0.848 0.152 0.000
I46 Cardiac arrest
0.844 0.156 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.841 0.159 0.000
G93 Other disorders of brain
0.840 0.160 0.000
M15-M19 Arthrosis
0.839 0.161 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.835 0.165 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.829 0.171 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.829 0.171 0.000
C25 Malignant neoplasm of pancreas
0.829 0.171 0.000
J95-J99 Other diseases of the respiratory system
0.828 0.172 0.000
T43.2 Other and unspecified antidepressants
0.825 0.175 0.000
M84 Disorders of continuity of bone
0.825 0.175 0.000
S61 Open wound of wrist and hand
0.823 0.177 0.000
E78.0 Pure hypercholesterolaemia
0.823 0.177 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.823 0.177 0.000
G20 Parkinson's disease
0.817 0.183 0.000
G40-G47 Episodic and paroxysmal disorders
0.817 0.183 0.000
M50-M54 Other dorsopathies
0.816 0.184 0.000
I42.9 Cardiomyopathy, unspecified
0.815 0.185 0.000
S10-S19 Injuries to the neck
0.813 0.187 0.000
M79.8 Other specified soft tissue disorders
0.812 0.188 0.000
I63 Cerebral infarction
0.810 0.190 0.000
W00-W19 Falls
0.809 0.191 0.000
M16 Coxarthrosis [arthrosis of hip]
0.809 0.191 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.808 0.192 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.808 0.192 0.000
S06 Intracranial injury
0.808 0.192 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.803 0.197 0.000
M79.6 Pain in limb
0.801 0.199 0.000
M45-M49 Spondylopathies
0.798 0.202 0.000
L20-L30 Dermatitis and eczema
0.797 0.203 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.796 0.204 0.000
M16.1 Other primary coxarthrosis
0.796 0.204 0.000
F32.0 Mild depressive episode
0.796 0.204 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.794 0.206 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.794 0.206 0.000
I50 Heart failure
0.794 0.206 0.000
I51.7 Cardiomegaly
0.793 0.207 0.000
F60-F69 Disorders of adult personality and behaviour
0.793 0.207 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.793 0.207 0.000
D04 Carcinoma in situ of skin
0.793 0.207 0.000
V10-V19 Pedal cyclist injured in transport accident
0.792 0.208 0.000
F33 Recurrent depressive disorder
0.791 0.209 0.000
C51-C58 Malignant neoplasms of female genital organs
0.790 0.210 0.000
T58 Toxic effect of carbon monoxide
0.789 0.211 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.788 0.212 0.000
I42.6 Alcoholic cardiomyopathy
0.787 0.213 0.000
S51 Open wound of forearm
0.786 0.214 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.785 0.214 0.000
S82 Fracture of lower leg, including ankle
0.782 0.218 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.779 0.221 0.000
T86.1 Kidney transplant failure and rejection
0.778 0.222 0.000
C71.1 Frontal lobe
0.778 0.222 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.777 0.223 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.777 0.223 0.000
I12 Hypertensive renal disease
0.775 0.225 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.775 0.225 0.000
M67.8 Other specified disorders of synovium and tendon
0.774 0.226 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.774 0.226 0.000
I31.9 Disease of pericardium, unspecified
0.773 0.227 0.000
S20-S29 Injuries to the thorax
0.773 0.227 0.000
I35 Nonrheumatic aortic valve disorders
0.773 0.227 0.000
D03 Melanoma in situ
0.771 0.229 0.000
C44 Other malignant neoplasms of skin
0.771 0.229 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.771 0.229 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.770 0.230 0.000
T85.2 Mechanical complication of intraocular lens
0.768 0.232 0.000
D05 Carcinoma in situ of breast
0.767 0.233 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.767 0.233 0.000
D69 Purpura and other haemorrhagic conditions
0.766 0.234 0.000
J98 Other respiratory disorders
0.765 0.235 0.000
S70-S79 Injuries to the hip and thigh
0.765 0.235 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.764 0.236 0.000
C17 Malignant neoplasm of small intestine
0.763 0.237 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.762 0.238 0.000
S52.8 Fracture of other parts of forearm
0.761 0.239 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.760 0.240 0.000
I21.4 Acute subendocardial myocardial infarction
0.760 0.240 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.760 0.240 0.000
I05-I09 Chronic rheumatic heart diseases
0.760 0.240 0.000
E86 Volume depletion
0.760 0.240 0.000
D37.4 Colon
0.759 0.241 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.759 0.241 0.000
M65.3 Trigger finger
0.757 0.243 0.000
F10.1 Harmful use
0.757 0.243 0.000
E40-E46 Malnutrition
0.757 0.243 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.757 0.243 0.000
G40 Epilepsy
0.755 0.245 0.000
I25 Chronic ischaemic heart disease
0.755 0.245 0.000
D60-D64 Aplastic and other anaemias
0.753 0.247 0.000
T42.4 Benzodiazepines
0.752 0.248 0.000
D51 Vitamin B12 deficiency anaemia
0.752 0.248 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.752 0.248 0.000
C25.0 Head of pancreas
0.751 0.249 0.000
M89 Other disorders of bone
0.750 0.250 0.000
F40 Phobic anxiety disorders
0.750 0.250 0.000
S40-S49 Injuries to the shoulder and upper arm
0.749 0.251 0.000
L30 Other dermatitis
0.748 0.252 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.748 0.252 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.748 0.252 0.000
E22 Hyperfunction of pituitary gland
0.748 0.252 0.000
F31 Bipolar affective disorder
0.748 0.252 0.000
E23 Hypofunction and other disorders of pituitary gland
0.748 0.252 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.745 0.255 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.745 0.255 0.000
I61 Intracerebral haemorrhage
0.745 0.255 0.000
I51.4 Myocarditis, unspecified
0.745 0.255 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.743 0.257 0.000
I20 Angina pectoris
0.741 0.259 0.000
T63 Toxic effect of contact with venomous animals
0.739 0.261 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.739 0.261 0.000
D50 Iron deficiency anaemia
0.739 0.261 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.739 0.261 0.000
I42.2 Other hypertrophic cardiomyopathy
0.738 0.262 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.737 0.263 0.000
T51.9 Alcohol, unspecified
0.736 0.264 0.000
C44.6 Skin of upper limb, including shoulder
0.735 0.265 0.000
M72 Fibroblastic disorders
0.734 0.266 0.000
M81.4 Drug-induced osteoporosis
0.734 0.266 0.000
S64 Injury of nerves at wrist and hand level
0.733 0.267 0.000
T79-T79 Certain early complications of trauma
0.732 0.268 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.731 0.269 0.000
D55-D59 Haemolytic anaemias
0.731 0.269 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.730 0.270 0.000
J40-J47 Chronic lower respiratory diseases
0.730 0.270 0.000
X60-X84 Intentional self-harm
0.730 0.270 0.000
S82.8 Fractures of other parts of lower leg
0.729 0.271 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.728 0.272 0.000
M77 Other enthesopathies
0.728 0.272 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.727 0.273 0.000
I12.0 Hypertensive renal disease with renal failure
0.727 0.273 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.727 0.273 0.000
I44 Atrioventricular and left bundle-branch block
0.726 0.274 0.000
E00-E07 Disorders of thyroid gland
0.726 0.274 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.725 0.274 0.000
S52.6 Fracture of lower end of both ulna and radius
0.725 0.275 0.000
S69 Other and unspecified injuries of wrist and hand
0.725 0.275 0.000
G62 Other polyneuropathies
0.725 0.275 0.000
M05-M14 Inflammatory polyarthropathies
0.724 0.276 0.000
M00-M03 Infectious arthropathies
0.724 0.276 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.724 0.276 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.724 0.276 0.000
I45 Other conduction disorders
0.723 0.277 0.000
E27 Other disorders of adrenal gland
0.723 0.277 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.722 0.278 0.000
V80-V89 Other land transport accidents
0.722 0.278 0.000
L60-L75 Disorders of skin appendages
0.722 0.278 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.721 0.279 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.721 0.279 0.000
G95 Other diseases of spinal cord
0.720 0.280 0.000
D52 Folate deficiency anaemia
0.720 0.280 0.000
M87 Osteonecrosis
0.720 0.280 0.000
T91 Sequelae of injuries of neck and trunk
0.719 0.281 0.000
M91-M94 Chondropathies
0.719 0.281 0.000
G93.6 Cerebral oedema
0.718 0.282 0.000
T86.0 Bone-marrow transplant rejection
0.717 0.283 0.000
Y83.4 Other reconstructive surgery
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.717 0.283 0.000
S05 Injury of eye and orbit
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I36 Nonrheumatic tricuspid valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
I30 Acute pericarditis
0.716 0.284 0.000
W20-W49 Exposure to inanimate mechanical forces
0.715 0.285 0.000
M83 Adult osteomalacia
0.714 0.285 0.000
M82 Osteoporosis in diseases classified elsewhere
0.714 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.714 0.286 0.000
F80-F89 Disorders of psychological development
0.714 0.286 0.000
F70-F79 Mental retardation
0.714 0.286 0.000
F32.1 Moderate depressive episode
0.714 0.286 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.714 0.286 0.000
I50.9 Heart failure, unspecified
0.714 0.286 0.000
L30.9 Dermatitis, unspecified
0.714 0.286 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.714 0.286 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.713 0.287 0.000
J98.1 Pulmonary collapse
0.713 0.287 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.713 0.287 0.000
M81.8 Other osteoporosis
0.712 0.288 0.000
M81.6 Localised osteoporosis [Lequesne]
0.712 0.288 0.000
M81.5 Idiopathic osteoporosis
0.712 0.288 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.712 0.288 0.000
M81.2 Osteoporosis of disuse
0.712 0.288 0.000
M81.1 Postoophorectomy osteoporosis
0.712 0.288 0.000
M81.0 Postmenopausal osteoporosis
0.712 0.288 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.711 0.289 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.710 0.290 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.710 0.290 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.710 0.290 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.710 0.290 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.710 0.290 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.710 0.290 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.710 0.290 0.000
C15 Malignant neoplasm of oesophagus
0.710 0.290 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.710 0.290 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.708 0.292 0.000
D80-D89 Certain disorders involving the immune mechanism
0.708 0.292 0.000
F10.2 Dependence syndrome
0.707 0.293 0.000
I38 Endocarditis, valve unspecified
0.707 0.293 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.706 0.294 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.705 0.295 0.000
S61.0 Open wound of finger(s) without damage to nail
0.704 0.296 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.704 0.296 0.000
C71.9 Brain, unspecified
0.703 0.297 0.000
S90-S99 Injuries to the ankle and foot
0.703 0.297 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.703 0.297 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.703 0.297 0.000
S02 Fracture of skull and facial bones
0.702 0.297 0.000
S86 Injury of muscle and tendon at lower leg level
0.702 0.298 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.702 0.298 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.701 0.299 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.701 0.299 0.000
J20-J22 Other acute lower respiratory infections
0.701 0.299 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.701 0.299 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.701 0.299 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.701 0.299 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.701 0.299 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.701 0.299 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.701 0.299 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.701 0.299 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.701 0.299 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.701 0.299 0.000
T36 Poisoning by systemic antibiotics
0.701 0.299 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.700 0.300 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.700 0.300 0.000
T66-T78 Other and unspecified effects of external causes
0.700 0.300 0.000
I42.8 Other cardiomyopathies
0.700 0.300 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.700 0.300 0.000
I42.5 Other restrictive cardiomyopathy
0.700 0.300 0.000
I42.4 Endocardial fibroelastosis
0.700 0.300 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.700 0.300 0.000
M88 Paget's disease of bone [osteitis deformans]
0.699 0.301 0.000
M40-M43 Deforming dorsopathies
0.699 0.301 0.000
M46 Other inflammatory spondylopathies
0.699 0.301 0.000
T65 Toxic effect of other and unspecified substances
0.698 0.302 0.000
T62 Toxic effect of other noxious substances eaten as food
0.698 0.302 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.698 0.302 0.000
T60 Toxic effect of pesticides
0.698 0.302 0.000
T59 Toxic effect of other gases, fumes and vapours
0.698 0.302 0.000
T57 Toxic effect of other inorganic substances
0.698 0.302 0.000
T56 Toxic effect of metals
0.698 0.302 0.000
T54 Toxic effect of corrosive substances
0.698 0.302 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.698 0.302 0.000
T52 Toxic effect of organic solvents
0.698 0.302 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.698 0.302 0.000
T55 Toxic effect of soaps and detergents
0.698 0.302 0.000
S59 Other and unspecified injuries of forearm
0.698 0.302 0.000
S58 Traumatic amputation of forearm
0.698 0.302 0.000
S57 Crushing injury of forearm
0.698 0.302 0.000
S56 Injury of muscle and tendon at forearm level
0.698 0.302 0.000
S55 Injury of blood vessels at forearm level
0.698 0.302 0.000
S54 Injury of nerves at forearm level
0.698 0.302 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.698 0.302 0.000
S89 Other and unspecified injuries of lower leg
0.698 0.302 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.697 0.303 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.697 0.303 0.000
M54 Dorsalgia
0.697 0.303 0.000
F41 Other anxiety disorders
0.696 0.304 0.000
C60-C63 Malignant neoplasms of male genital organs
0.696 0.304 0.000
G93.8 Other specified disorders of brain
0.695 0.305 0.000
F38 Other mood [affective] disorders
0.695 0.305 0.000
F34 Persistent mood [affective] disorders
0.695 0.305 0.000
F30 Manic episode
0.695 0.305 0.000
F39 Unspecified mood [affective] disorder
0.695 0.305 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.695 0.305 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.693 0.307 0.000
I46.9 Cardiac arrest, unspecified
0.693 0.307 0.000
M85 Other disorders of bone density and structure
0.692 0.308 0.000
I23 Certain current complications following acute myocardial infarction
0.691 0.309 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.691 0.309 0.000
D69.6 Thrombocytopenia, unspecified
0.690 0.310 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.690 0.310 0.000
V20-V29 Motorcycle rider injured in transport accident
0.689 0.310 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.689 0.311 0.000
Y35-Y36 Legal intervention and operations of war
0.689 0.311 0.000
Y10-Y34 Event of undetermined intent
0.689 0.311 0.000
Y00-Y09 Assault
0.689 0.311 0.000
X85-X99 Assault
0.689 0.311 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.689 0.311 0.000
X50-X57 Overexertion, travel and privation
0.689 0.311 0.000
X30-X39 Exposure to forces of nature
0.689 0.311 0.000
X20-X29 Contact with venomous animals and plants
0.689 0.311 0.000
X10-X19 Contact with heat and hot substances
0.689 0.311 0.000
X00-X09 Exposure to smoke, fire and flames
0.689 0.311 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.689 0.311 0.000
W75-W84 Other accidental threats to breathing
0.689 0.311 0.000
W65-W74 Accidental drowning and submersion
0.689 0.311 0.000
W50-W64 Exposure to animate mechanical forces
0.689 0.311 0.000
V98-V99 Other and unspecified transport accidents
0.689 0.311 0.000
V95-V97 Air and space transport accidents
0.689 0.311 0.000
V90-V94 Water transport accidents
0.689 0.311 0.000
V70-V79 Bus occupant injured in transport accident
0.689 0.311 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.689 0.311 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.689 0.311 0.000
V40-V49 Car occupant injured in transport accident
0.689 0.311 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.689 0.311 0.000
V01-V09 Pedestrian injured in transport accident
0.689 0.311 0.000
E29 Testicular dysfunction
0.689 0.311 0.000
I47 Paroxysmal tachycardia
0.689 0.311 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.689 0.311 0.000
M66 Spontaneous rupture of synovium and tendon
0.689 0.311 0.000
J44 Other chronic obstructive pulmonary disease
0.689 0.311 0.000
S62 Fracture at wrist and hand level
0.688 0.312 0.000
S80 Superficial injury of lower leg
0.688 0.312 0.000
E21.0 Primary hyperparathyroidism
0.687 0.313 0.000
W18 Other fall on same level
0.687 0.313 0.000
U80 Agent resistant to penicillin and related antibiotics
0.687 0.313 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.687 0.313 0.000
I33 Acute and subacute endocarditis
0.685 0.315 0.000
C53 Malignant neoplasm of cervix uteri
0.685 0.315 0.000
T93 Sequelae of injuries of lower limb
0.685 0.315 0.000
M65.8 Other synovitis and tenosynovitis
0.683 0.317 0.000
S08 Traumatic amputation of part of head
0.683 0.317 0.000
S07 Crushing injury of head
0.683 0.317 0.000
S04 Injury of cranial nerves
0.683 0.317 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.683 0.317 0.000
M80 Osteoporosis with pathological fracture
0.683 0.317 0.000
S06.5 Traumatic subdural haemorrhage
0.682 0.318 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.681 0.319 0.000
F43 Reaction to severe stress, and adjustment disorders
0.681 0.319 0.000
I22 Subsequent myocardial infarction
0.681 0.319 0.000
F10.3 Withdrawal state
0.681 0.319 0.000
I51.9 Heart disease, unspecified
0.681 0.319 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.680 0.320 0.000
S52.9 Fracture of forearm, part unspecified
0.680 0.320 0.000
S52.7 Multiple fractures of forearm
0.680 0.320 0.000
S52.4 Fracture of shafts of both ulna and radius
0.680 0.320 0.000
S52.3 Fracture of shaft of radius
0.680 0.320 0.000
S52.2 Fracture of shaft of ulna
0.680 0.320 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.679 0.321 0.000
M86 Osteomyelitis
0.679 0.321 0.000
T90 Sequelae of injuries of head
0.678 0.321 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.678 0.322 0.000
M79.1 Myalgia
0.678 0.322 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.676 0.324 0.000
T51.8 Other alcohols
0.675 0.325 0.000
T51.3 Fusel oil
0.675 0.325 0.000
T51.2 2-Propanol
0.675 0.325 0.000
T51.1 Methanol
0.675 0.325 0.000
M76 Enthesopathies of lower limb, excluding foot
0.674 0.326 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.674 0.326 0.000
S01 Open wound of head
0.674 0.326 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.674 0.326 0.000
M65.34 Trigger finger-Hand
0.674 0.326 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.673 0.326 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.673 0.326 0.000
D37.7 Other digestive organs
0.673 0.327 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.673 0.327 0.000
M79.69 Pain in limb (Site unspecified)
0.673 0.327 0.000
M71 Other bursopathies
0.673 0.327 0.000
Chapter I Certain infectious and parasitic diseases
0.673 0.327 0.000
I44.7 Left bundle-branch block, unspecified
0.672 0.328 0.000
S67 Crushing injury of wrist and hand
0.672 0.328 0.000
S65 Injury of blood vessels at wrist and hand level
0.672 0.328 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.672 0.328 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.672 0.328 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.672 0.328 0.000
F99-F99 Unspecified mental disorder
0.671 0.328 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.671 0.329 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.671 0.329 0.000
S50 Superficial injury of forearm
0.671 0.329 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.670 0.330 0.000
M67.1 Other contracture of tendon (sheath)
0.670 0.330 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.669 0.331 0.000
F32.8 Other depressive episodes
0.669 0.331 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.668 0.331 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.668 0.331 0.000
T82.3 Mechanical complication of other vascular grafts
0.668 0.331 0.000
T82.1 Mechanical complication of cardiac electronic device
0.668 0.331 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.668 0.331 0.000
S60 Superficial injury of wrist and hand
0.668 0.331 0.000
I46.0 Cardiac arrest with successful resuscitation
0.668 0.332 0.000
M79.60 Pain in limb (Multiple sites)
0.668 0.332 0.000
D37.5 Rectum
0.668 0.332 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.668 0.332 0.000
S52.51 Fracture of lower end of radius (open)
0.668 0.332 0.000
G30-G32 Other degenerative diseases of the nervous system
0.666 0.334 0.000
D46 Myelodysplastic syndromes
0.666 0.334 0.000
S68 Traumatic amputation of wrist and hand
0.665 0.335 0.000
G93.2 Benign intracranial hypertension
0.665 0.335 0.000
T43.9 Psychotropic drug, unspecified
0.664 0.336 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.664 0.336 0.000
T43.6 Psychostimulants with abuse potential
0.664 0.336 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.664 0.336 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.664 0.336 0.000
G61 Inflammatory polyneuropathy
0.664 0.336 0.000
G91 Hydrocephalus
0.664 0.336 0.000
C25.9 Pancreas, unspecified
0.664 0.336 0.000
D04.3 Skin of other and unspecified parts of face
0.663 0.337 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.663 0.337 0.000
L89 Decubitus ulcer
0.663 0.337 0.000
G70-G73 Diseases of myoneural junction and muscle
0.662 0.338 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.660 0.340 0.000
D09 Carcinoma in situ of other and unspecified sites
0.659 0.341 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.659 0.341 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.659 0.341 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.659 0.341 0.000
E65-E68 Obesity and other hyperalimentation
0.659 0.341 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.658 0.342 0.000
M18 Arthrosis of first carpometacarpal joint
0.658 0.342 0.000
M81.98 Osteoporosis, unspecified (Other)
0.657 0.343 0.000
I20.8 Other forms of angina pectoris
0.657 0.343 0.000
E85 Amyloidosis
0.657 0.343 0.000
E84 Cystic fibrosis
0.657 0.343 0.000
E79 Disorders of purine and pyrimidine metabolism
0.657 0.343 0.000
E77 Disorders of glycoprotein metabolism
0.657 0.343 0.000
E76 Disorders of glycosaminoglycan metabolism
0.657 0.343 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.657 0.343 0.000
E74 Other disorders of carbohydrate metabolism
0.657 0.343 0.000
E73 Lactose intolerance
0.657 0.343 0.000
E72 Other disorders of amino-acid metabolism
0.657 0.343 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.657 0.343 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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