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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs41267649
log Bayes Factor = 27.6616
Chromosome 6   position 33,384,473  (GRCh37) Explore rs41267649 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
0.999 0.001 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.994 0.006 0.000
Chapter VII Diseases of the eye and adnexa
0.992 0.008 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.991 0.009 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.990 0.010 0.000
E10.3 With ophthalmic complications
0.989 0.011 0.000
H30-H36 Disorders of choroid and retina
0.986 0.014 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.986 0.014 0.000
E16 Other disorders of pancreatic internal secretion
0.983 0.017 0.000
H36 Retinal disorders in diseases classified elsewhere
0.983 0.017 0.000
H36.0 Diabetic retinopathy
0.982 0.018 0.000
M70-M79 Other soft tissue disorders
0.980 0.020 0.000
M05 Seropositive rheumatoid arthritis
0.980 0.020 0.000
E16.2 Hypoglycaemia, unspecified
0.979 0.021 0.000
Chapter VIII Diseases of the ear and mastoid process
0.976 0.024 0.000
E10.1 With ketoacidosis
0.975 0.025 0.000
E11.9 Without complications
0.974 0.026 0.000
E11.3 With ophthalmic complications
0.974 0.026 0.000
D50-D53 Nutritional anaemias
0.969 0.031 0.000
Chapter XX External causes of morbidity and mortality
0.967 0.033 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.965 0.035 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.956 0.044 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.952 0.048 0.000
E10.4 With neurological complications
0.947 0.053 0.000
D50 Iron deficiency anaemia
0.946 0.054 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.942 0.058 0.000
Chapter I Certain infectious and parasitic diseases
0.932 0.068 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.932 0.068 0.000
M50-M54 Other dorsopathies
0.920 0.080 0.000
D50.8 Other iron deficiency anaemias
0.914 0.086 0.000
Chapter X Diseases of the respiratory system
0.908 0.092 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.907 0.093 0.000
M65-M68 Disorders of synovium and tendon
0.904 0.096 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.904 0.096 0.000
S40-S49 Injuries to the shoulder and upper arm
0.901 0.099 0.000
E14 Unspecified diabetes mellitus
0.900 0.100 0.000
M75 Shoulder lesions
0.889 0.111 0.000
H80-H83 Diseases of inner ear
0.886 0.114 0.000
M80-M85 Disorders of bone density and structure
0.884 0.116 0.000
H65-H75 Diseases of middle ear and mastoid
0.884 0.116 0.000
Chapter VI Diseases of the nervous system
0.873 0.127 0.000
E00-E07 Disorders of thyroid gland
0.870 0.130 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.869 0.131 0.000
M79.1 Myalgia
0.867 0.133 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.863 0.137 0.000
E11.2 With renal complications
0.860 0.140 0.000
S70-S79 Injuries to the hip and thigh
0.858 0.142 0.000
B35-B49 Mycoses
0.858 0.142 0.000
J40-J47 Chronic lower respiratory diseases
0.857 0.143 0.000
J47 Bronchiectasis
0.851 0.149 0.000
H60-H62 Diseases of external ear
0.848 0.152 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.846 0.154 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.845 0.155 0.000
T66-T78 Other and unspecified effects of external causes
0.841 0.159 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.841 0.159 0.000
E11.4 With neurological complications
0.839 0.161 0.000
E10.2 With renal complications
0.838 0.162 0.000
S00-S09 Injuries to the head
0.836 0.164 0.000
E40-E46 Malnutrition
0.834 0.166 0.000
D50.9 Iron deficiency anaemia, unspecified
0.829 0.171 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.828 0.172 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.828 0.172 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.821 0.179 0.000
M91-M94 Chondropathies
0.820 0.180 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.819 0.181 0.000
M75.5 Bursitis of shoulder
0.818 0.182 0.000
H55-H59 Other disorders of eye and adnexa
0.818 0.182 0.000
M54 Dorsalgia
0.815 0.185 0.000
M65 Synovitis and tenosynovitis
0.811 0.189 0.000
E10.5 With peripheral circulatory complications
0.808 0.192 0.000
M06.3 Rheumatoid nodule
0.806 0.194 0.000
W50-W64 Exposure to animate mechanical forces
0.804 0.196 0.000
H34 Retinal vascular occlusions
0.800 0.200 0.000
M40-M43 Deforming dorsopathies
0.796 0.204 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.795 0.205 0.000
D51 Vitamin B12 deficiency anaemia
0.794 0.206 0.000
D69 Purpura and other haemorrhagic conditions
0.793 0.207 0.000
M75.0 Adhesive capsulitis of shoulder
0.793 0.207 0.000
B25-B34 Other viral diseases
0.792 0.207 0.000
G62 Other polyneuropathies
0.792 0.208 0.000
E14.3 With ophthalmic complications
0.792 0.208 0.000
G63.2 Diabetic polyneuropathy
0.791 0.209 0.000
M84 Disorders of continuity of bone
0.789 0.211 0.000
Chapter XXII Codes for special purposes
0.784 0.216 0.000
M06.0 Seronegative rheumatoid arthritis
0.782 0.218 0.000
E11.5 With peripheral circulatory complications
0.782 0.218 0.000
M79.0 Rheumatism, unspecified
0.782 0.218 0.000
M11 Other crystal arthropathies
0.781 0.219 0.000
M10 Gout
0.779 0.221 0.000
Y95 Nosocomial condition
0.779 0.221 0.000
M75.4 Impingement syndrome of shoulder
0.779 0.221 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.777 0.223 0.000
S70 Superficial injury of hip and thigh
0.774 0.226 0.000
S42 Fracture of shoulder and upper arm
0.770 0.230 0.000
J42 Unspecified chronic bronchitis
0.769 0.231 0.000
Q60-Q64 Congenital malformations of the urinary system
0.767 0.233 0.000
T79-T79 Certain early complications of trauma
0.767 0.233 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.766 0.234 0.000
B37 Candidiasis
0.766 0.234 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.764 0.235 0.000
E04 Other non-toxic goitre
0.762 0.238 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.761 0.239 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.760 0.240 0.000
T78 Adverse effects, not elsewhere classified
0.759 0.241 0.000
M65.3 Trigger finger
0.758 0.242 0.000
M51 Other intervertebral disk disorders
0.758 0.242 0.000
V80-V89 Other land transport accidents
0.757 0.243 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.757 0.243 0.000
G90-G99 Other disorders of the nervous system
0.756 0.244 0.000
H60 Otitis externa
0.754 0.246 0.000
M20-M25 Other joint disorders
0.753 0.247 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.753 0.247 0.000
M72 Fibroblastic disorders
0.752 0.248 0.000
V10-V19 Pedal cyclist injured in transport accident
0.751 0.249 0.000
H31 Other disorders of choroid
0.750 0.250 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.750 0.250 0.000
E11.1 With ketoacidosis
0.750 0.250 0.000
H83 Other diseases of inner ear
0.748 0.252 0.000
J09-J18 Influenza and pneumonia
0.748 0.252 0.000
E20-E35 Disorders of other endocrine glands
0.746 0.254 0.000
M79.2 Neuralgia and neuritis, unspecified
0.744 0.256 0.000
M79.7 Fibromyalgia
0.743 0.257 0.000
M60-M63 Disorders of muscles
0.740 0.260 0.000
D60-D64 Aplastic and other anaemias
0.739 0.261 0.000
M79.9 Soft tissue disorder, unspecified
0.739 0.261 0.000
M79.10 Myalgia (Multiple sites)
0.738 0.262 0.000
T90 Sequelae of injuries of head
0.736 0.264 0.000
M24 Other specific joint derangements
0.735 0.265 0.000
M00-M03 Infectious arthropathies
0.734 0.266 0.000
E14.9 Without complications
0.734 0.266 0.000
D66 Hereditary factor VIII deficiency
0.732 0.268 0.000
H81 Disorders of vestibular function
0.730 0.269 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.730 0.270 0.000
D80-D89 Certain disorders involving the immune mechanism
0.726 0.274 0.000
M79.16 Myalgia (Lower leg)
0.723 0.277 0.000
H74 Other disorders of middle ear and mastoid
0.723 0.277 0.000
X20-X29 Contact with venomous animals and plants
0.722 0.277 0.000
M86-M90 Other osteopathies
0.720 0.279 0.000
H71 Cholesteatoma of middle ear
0.720 0.280 0.000
M65.34 Trigger finger-Hand
0.720 0.280 0.000
S43.0 Dislocation of shoulder joint
0.718 0.282 0.000
J00-J06 Acute upper respiratory infections
0.718 0.282 0.000
E10.8 With unspecified complications
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E10.6 With other specified complications
0.717 0.283 0.000
E10.0 With coma
0.717 0.283 0.000
E13 Other specified diabetes mellitus
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M14 Arthropathies in other diseases classified elsewhere
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.717 0.283 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.717 0.283 0.000
M06.4 Inflammatory polyarthropathy
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
E11.8 With unspecified complications
0.716 0.283 0.000
E11.7 With multiple complications
0.716 0.283 0.000
E11.6 With other specified complications
0.716 0.283 0.000
E11.0 With coma
0.716 0.283 0.000
Q80-Q89 Other congenital malformations
0.716 0.284 0.000
S60-S69 Injuries to the wrist and hand
0.716 0.284 0.000
H72 Perforation of tympanic membrane
0.715 0.285 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.715 0.285 0.000
W00-W19 Falls
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
M79.18 Myalgia (Other)
0.715 0.285 0.000
E46 Unspecified protein-energy malnutrition
0.715 0.285 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.714 0.286 0.000
G62.9 Polyneuropathy, unspecified
0.713 0.287 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.712 0.288 0.000
B35 Dermatophytosis
0.712 0.288 0.000
D55-D59 Haemolytic anaemias
0.710 0.289 0.000
G61 Inflammatory polyneuropathy
0.710 0.290 0.000
E15 Nondiabetic hypoglycaemic coma
0.710 0.290 0.000
J60-J70 Lung diseases due to external agents
0.709 0.291 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.709 0.291 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.708 0.291 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.707 0.293 0.000
H30 Chorioretinal inflammation
0.707 0.293 0.000
E06 Thyroiditis
0.707 0.293 0.000
J95-J99 Other diseases of the respiratory system
0.705 0.295 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.705 0.295 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.705 0.295 0.000
E16.4 Abnormal secretion of gastrin
0.705 0.295 0.000
E16.3 Increased secretion of glucagon
0.705 0.295 0.000
E16.1 Other hypoglycaemia
0.705 0.295 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.705 0.295 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.705 0.295 0.000
G30-G32 Other degenerative diseases of the nervous system
0.703 0.297 0.000
M76 Enthesopathies of lower limb, excluding foot
0.703 0.297 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.703 0.297 0.000
M79.5 Residual foreign body in soft tissue
0.703 0.297 0.000
M05.8 Other seropositive rheumatoid arthritis
0.702 0.297 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.702 0.297 0.000
M05.2 Rheumatoid vasculitis
0.702 0.297 0.000
M05.1 Rheumatoid lung disease
0.702 0.297 0.000
M05.0 Felty's syndrome
0.702 0.297 0.000
S10-S19 Injuries to the neck
0.701 0.299 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.701 0.299 0.000
H80 Otosclerosis
0.698 0.302 0.000
H53-H54 Visual disturbances and blindness
0.698 0.302 0.000
M54.2 Cervicalgia
0.697 0.303 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.696 0.304 0.000
D53 Other nutritional anaemias
0.695 0.305 0.000
Y35-Y36 Legal intervention and operations of war
0.693 0.307 0.000
Y10-Y34 Event of undetermined intent
0.693 0.307 0.000
Y00-Y09 Assault
0.693 0.307 0.000
X85-X99 Assault
0.693 0.307 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.693 0.307 0.000
X30-X39 Exposure to forces of nature
0.693 0.307 0.000
X10-X19 Contact with heat and hot substances
0.693 0.307 0.000
X00-X09 Exposure to smoke, fire and flames
0.693 0.307 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.693 0.307 0.000
W75-W84 Other accidental threats to breathing
0.693 0.307 0.000
W65-W74 Accidental drowning and submersion
0.693 0.307 0.000
V98-V99 Other and unspecified transport accidents
0.693 0.307 0.000
V95-V97 Air and space transport accidents
0.693 0.307 0.000
V90-V94 Water transport accidents
0.693 0.307 0.000
V70-V79 Bus occupant injured in transport accident
0.693 0.307 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.693 0.307 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.693 0.307 0.000
V40-V49 Car occupant injured in transport accident
0.693 0.307 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.693 0.307 0.000
V20-V29 Motorcycle rider injured in transport accident
0.693 0.307 0.000
V01-V09 Pedestrian injured in transport accident
0.693 0.307 0.000
M71 Other bursopathies
0.693 0.307 0.000
M67 Other disorders of synovium and tendon
0.693 0.307 0.000
M50 Cervical disk disorders
0.693 0.307 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.693 0.307 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.692 0.308 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.692 0.308 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.692 0.308 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.692 0.308 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.692 0.308 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.692 0.308 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.692 0.308 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.692 0.308 0.000
M94 Other disorders of cartilage
0.692 0.308 0.000
A80-A89 Viral infections of the central nervous system
0.691 0.309 0.000
S02 Fracture of skull and facial bones
0.690 0.310 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.689 0.311 0.000
D68 Other coagulation defects
0.689 0.311 0.000
B15-B19 Viral hepatitis
0.688 0.312 0.000
W55 Bitten or struck by other mammals
0.688 0.312 0.000
H10-H13 Disorders of conjunctiva
0.687 0.313 0.000
A00-A09 Intestinal infectious diseases
0.686 0.314 0.000
H65 Nonsuppurative otitis media
0.686 0.314 0.000
T33-T35 Frostbite
0.686 0.314 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.686 0.314 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.686 0.314 0.000
T00-T07 Injuries involving multiple body regions
0.686 0.314 0.000
X60-X84 Intentional self-harm
0.685 0.315 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.685 0.315 0.000
H73 Other disorders of tympanic membrane
0.685 0.315 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.684 0.316 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.683 0.317 0.000
S05 Injury of eye and orbit
0.683 0.317 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.682 0.318 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.682 0.318 0.000
H60.9 Otitis externa, unspecified
0.681 0.318 0.000
T78.4 Allergy, unspecified
0.681 0.319 0.000
E50-E64 Other nutritional deficiencies
0.680 0.320 0.000
S40 Superficial injury of shoulder and upper arm
0.680 0.320 0.000
B37.8 Candidiasis of other sites
0.679 0.321 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.678 0.322 0.000
D50.1 Sideropenic dysphagia
0.678 0.322 0.000
M77 Other enthesopathies
0.676 0.324 0.000
H43-H45 Disorders of vitreous body and globe
0.675 0.324 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.675 0.325 0.000
Q35-Q37 Cleft lip and cleft palate
0.675 0.325 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.675 0.325 0.000
B34 Viral infection of unspecified site
0.674 0.326 0.000
M66 Spontaneous rupture of synovium and tendon
0.673 0.327 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.673 0.327 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.673 0.327 0.000
H05 Disorders of orbit
0.671 0.329 0.000
D52 Folate deficiency anaemia
0.671 0.329 0.000
M85 Other disorders of bone density and structure
0.670 0.330 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.670 0.330 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.669 0.331 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.669 0.331 0.000
M43 Other deforming dorsopathies
0.668 0.332 0.000
B99-B99 Other infectious diseases
0.668 0.332 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.668 0.332 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.668 0.332 0.000
B65-B83 Helminthiases
0.668 0.332 0.000
B50-B64 Protozoal diseases
0.668 0.332 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.668 0.332 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.668 0.332 0.000
A75-A79 Rickettsioses
0.668 0.332 0.000
A70-A74 Other diseases caused by chlamydiae
0.668 0.332 0.000
A65-A69 Other spirochaetal diseases
0.668 0.332 0.000
A20-A28 Certain zoonotic bacterial diseases
0.668 0.332 0.000
A15-A19 Tuberculosis
0.668 0.332 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.668 0.332 0.000
M79.3 Panniculitis, unspecified
0.668 0.332 0.000
M06.34 Rheumatoid nodule (Hand)
0.667 0.333 0.000
S20-S29 Injuries to the thorax
0.667 0.333 0.000
E04.9 Non-toxic goitre, unspecified
0.667 0.333 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.666 0.334 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.665 0.335 0.000
H18 Other disorders of cornea
0.665 0.335 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.664 0.336 0.000
Q00-Q07 Congenital malformations of the nervous system
0.664 0.336 0.000
M54.5 Low back pain
0.664 0.336 0.000
Q43 Other congenital malformations of intestine
0.662 0.338 0.000
S01 Open wound of head
0.662 0.338 0.000
S90-S99 Injuries to the ankle and foot
0.661 0.339 0.000
S42.2 Fracture of upper end of humerus
0.660 0.340 0.000
M53 Other dorsopathies, not elsewhere classified
0.660 0.340 0.000
Q50-Q56 Congenital malformations of genital organs
0.659 0.341 0.000
M79.8 Other specified soft tissue disorders
0.659 0.341 0.000
S06 Intracranial injury
0.658 0.342 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.656 0.344 0.000
M51.2 Other specified intervertebral disk displacement
0.656 0.344 0.000
M07 Psoriatic and enteropathic arthropathies
0.656 0.344 0.000
H34.8 Other retinal vascular occlusions
0.655 0.345 0.000
B37.0 Candidal stomatitis
0.655 0.345 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.654 0.346 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.653 0.347 0.000
M24.2 Disorder of ligament
0.653 0.347 0.000
T98 Sequelae of other and unspecified effects of external causes
0.652 0.348 0.000
H55 Nystagmus and other irregular eye movements
0.650 0.349 0.000
T92 Sequelae of injuries of upper limb
0.650 0.350 0.000
E04.2 Non-toxic multinodular goitre
0.649 0.351 0.000
H83.0 Labyrinthitis
0.648 0.352 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.648 0.352 0.000
D67 Hereditary factor IX deficiency
0.648 0.352 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.648 0.352 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.646 0.354 0.000
S48 Traumatic amputation of shoulder and upper arm
0.646 0.354 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.646 0.354 0.000
S44 Injury of nerves at shoulder and upper arm level
0.646 0.354 0.000
S41 Open wound of shoulder and upper arm
0.646 0.354 0.000
S47 Crushing injury of shoulder and upper arm
0.646 0.354 0.000
T91 Sequelae of injuries of neck and trunk
0.646 0.354 0.000
E14.8 With unspecified complications
0.646 0.354 0.000
E14.7 With multiple complications
0.646 0.354 0.000
E14.6 With other specified complications
0.646 0.354 0.000
E14.5 With peripheral circulatory complications
0.646 0.354 0.000
E14.4 With neurological complications
0.646 0.354 0.000
E14.2 Withrenal complications
0.646 0.354 0.000
E14.1 With ketoacidosis
0.646 0.354 0.000
E14.0 With coma
0.646 0.354 0.000
M54.9 Dorsalgia, unspecified
0.645 0.355 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.644 0.356 0.000
M24.1 Other articular cartilage disorders
0.644 0.356 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.643 0.357 0.000
E07 Other disorders of thyroid
0.642 0.357 0.000
G62.0 Drug-induced polyneuropathy
0.642 0.358 0.000
T78.3 Angioneurotic oedema
0.642 0.358 0.000
M65.8 Other synovitis and tenosynovitis
0.642 0.358 0.000
H17 Corneal scars and opacities
0.642 0.358 0.000
M81 Osteoporosis without pathological fracture
0.642 0.358 0.000
M75.9 Shoulder lesion, unspecified
0.639 0.361 0.000
M75.8 Other shoulder lesions
0.638 0.362 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.637 0.363 0.000
H25-H28 Disorders of lens
0.636 0.364 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.635 0.365 0.000
H01 Other inflammation of eyelid
0.635 0.365 0.000
M25 Other joint disorders, not elsewhere classified
0.634 0.366 0.000
M83 Adult osteomalacia
0.634 0.366 0.000
M82 Osteoporosis in diseases classified elsewhere
0.634 0.366 0.000
H90-H95 Other disorders of ear
0.634 0.366 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.634 0.366 0.000
H70 Mastoiditis and related conditions
0.634 0.366 0.000
H69 Other disorders of Eustachian tube
0.634 0.366 0.000
H68 Eustachian salpingitis and obstruction
0.634 0.366 0.000
H67 Otitis media in diseases classified elsewhere
0.634 0.366 0.000
S70.0 Contusion of hip
0.634 0.366 0.000
M50.2 Other cervical disk displacement
0.633 0.367 0.000
G95 Other diseases of spinal cord
0.632 0.368 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.631 0.369 0.000
H02 Other disorders of eyelid
0.631 0.369 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.631 0.369 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.630 0.370 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.629 0.371 0.000
M75.2 Bicipital tendinitis
0.629 0.371 0.000
W20-W49 Exposure to inanimate mechanical forces
0.628 0.372 0.000
B44 Aspergillosis
0.628 0.372 0.000
A04 Other bacterial intestinal infections
0.626 0.374 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.626 0.374 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.625 0.374 0.000
M11.2 Other chondrocalcinosis
0.624 0.376 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.624 0.376 0.000
E00 Congenital iodine-deficiency syndrome
0.624 0.376 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.624 0.376 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.623 0.377 0.000
Y98 Lifestyle-related condition
0.623 0.377 0.000
Y97 Environmental-pollution-related condition
0.623 0.377 0.000
Y96 Work-related condition
0.623 0.377 0.000
M80 Osteoporosis with pathological fracture
0.623 0.377 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.622 0.378 0.000
M54.1 Radiculopathy
0.622 0.378 0.000
D69.6 Thrombocytopenia, unspecified
0.622 0.378 0.000
M79.19 Myalgia (Site unspecified)
0.621 0.378 0.000
M79.17 Myalgia (Ankle and foot)
0.621 0.378 0.000
M79.15 Myalgia (Pelvic region and thigh)
0.621 0.378 0.000
M79.14 Myalgia (Hand)
0.621 0.378 0.000
M79.13 Myalgia (Forearm)
0.621 0.378 0.000
M79.12 Myalgia (Upper arm)
0.621 0.378 0.000
M79.11 Myalgia (Shoulder region)
0.621 0.378 0.000
M10.9 Gout, unspecified
0.621 0.379 0.000
M84.0 Malunion of fracture
0.621 0.379 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.620 0.379 0.000
G60 Hereditary and idiopathic neuropathy
0.619 0.381 0.000
G64 Other disorders of peripheral nervous system
0.619 0.381 0.000
M84.4 Pathological fracture, not elsewhere classified
0.619 0.381 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.617 0.383 0.000
Q61 Cystic kidney disease
0.616 0.384 0.000
S79 Other and unspecified injuries of hip and thigh
0.615 0.384 0.000
S78 Traumatic amputation of hip and thigh
0.615 0.384 0.000
S77 Crushing injury of hip and thigh
0.615 0.384 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.615 0.384 0.000
S75 Injury of blood vessels at hip and thigh level
0.615 0.384 0.000
S74 Injury of nerves at hip and thigh level
0.615 0.384 0.000
S71 Open wound of hip and thigh
0.615 0.384 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.615 0.384 0.000
B48 Other mycoses, not elsewhere classified
0.615 0.385 0.000
B47 Mycetoma
0.615 0.385 0.000
B46 Zygomycosis
0.615 0.385 0.000
B45 Cryptococcosis
0.615 0.385 0.000
B43 Chromomycosis and phaeomycotic abscess
0.615 0.385 0.000
B42 Sporotrichosis
0.615 0.385 0.000
B41 Paracoccidioidomycosis
0.615 0.385 0.000
B40 Blastomycosis
0.615 0.385 0.000
B39 Histoplasmosis
0.615 0.385 0.000
B38 Coccidioidomycosis
0.615 0.385 0.000
B36 Other superficial mycoses
0.615 0.385 0.000
B49 Unspecified mycosis
0.615 0.385 0.000
J41 Simple and mucopurulent chronic bronchitis
0.615 0.385 0.000
S67 Crushing injury of wrist and hand
0.615 0.385 0.000
M35 Other systemic involvement of connective tissue
0.615 0.385 0.000
S70.1 Contusion of thigh
0.613 0.387 0.000
H61 Other disorders of external ear
0.613 0.387 0.000
H16 Keratitis
0.611 0.389 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.610 0.390 0.000
M79.28 Neuralgia and neuritis, unspecified (Other)
0.610 0.390 0.000
D69.5 Secondary thrombocytopenia
0.610 0.390 0.000
A30-A49 Other bacterial diseases
0.610 0.390 0.000
H00 Hordeolum and chalazion
0.608 0.392 0.000
M79.79 Fibromyalgia (Site unspecified)
0.608 0.392 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.608 0.392 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.606 0.394 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.606 0.394 0.000
T95 Sequelae of burns, corrosions and frostbite
0.606 0.394 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.606 0.394 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.606 0.394 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.606 0.394 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.606 0.394 0.000
G96 Other disorders of central nervous system
0.605 0.395 0.000
B25 Cytomegaloviral disease
0.604 0.396 0.000
T75 Effects of other external causes
0.603 0.397 0.000
T74 Maltreatment syndromes
0.603 0.397 0.000
T73 Effects of other deprivation
0.603 0.397 0.000
T70 Effects of air pressure and water pressure
0.603 0.397 0.000
T69 Other effects of reduced temperature
0.603 0.397 0.000
T67 Effects of heat and light
0.603 0.397 0.000
T71 Asphyxiation
0.603 0.397 0.000
T68 Hypothermia
0.603 0.397 0.000
T66 Unspecified effects of radiation
0.603 0.397 0.000
J14 Pneumonia due to Haemophilus influenzae
0.603 0.397 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.601 0.399 0.000
Y57 Other and unspecified drugs and medicaments
0.600 0.400 0.000
M79.96 Soft tissue disorder, unspecified (Lower leg)
0.600 0.400 0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents
0.600 0.400 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.600 0.400 0.000
S08 Traumatic amputation of part of head
0.599 0.400 0.000
S07 Crushing injury of head
0.599 0.400 0.000
S04 Injury of cranial nerves
0.599 0.400 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.599 0.400 0.000
J02 Acute pharyngitis
0.599 0.401 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.598 0.402 0.000
G61.8 Other inflammatory polyneuropathies
0.598 0.402 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.598 0.402 0.000
E45 Retarded development following protein-energy malnutrition
0.598 0.402 0.000
E43 Unspecified severe protein-energy malnutrition
0.598 0.402 0.000
E42 Marasmic kwashiorkor
0.598 0.402 0.000
E41 Nutritional marasmus
0.598 0.402 0.000
E40 Kwashiorkor
0.598 0.402 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.597 0.403 0.000
S42.1 Fracture of scapula
0.597 0.403 0.000
J01 Acute sinusitis
0.597 0.403 0.000
Q44.6 Cystic disease of liver
0.596 0.404 0.000
W17 Other fall from one level to another
0.596 0.404 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.596 0.404 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.594 0.406 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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