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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4357753
log Bayes Factor = 5.99351
Chromosome 12   position 112,740,709  (GRCh37) Explore rs4357753 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.000 1.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.001 0.999
I25.1 Atherosclerotic heart disease
0.000 0.001 0.999
I25.2 Old myocardial infarction
0.000 0.007 0.993
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.039 0.961
I21.9 Acute myocardial infarction, unspecified
0.000 0.048 0.952
I25.5 Ischaemic cardiomyopathy
0.000 0.117 0.883
I22 Subsequent myocardial infarction
0.000 0.121 0.879
I21.4 Acute subendocardial myocardial infarction
0.000 0.139 0.861
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.167 0.833
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.177 0.823
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.241 0.759
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.281 0.719
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.283 0.717
I25.4 Coronary artery aneurysm
0.000 0.315 0.685
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.339 0.661
I25.3 Aneurysm of heart
0.000 0.339 0.660
I24 Other acute ischaemic heart diseases
0.000 0.343 0.657
I23 Certain current complications following acute myocardial infarction
0.000 0.368 0.631
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.370 0.630
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.376 0.624
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.378 0.622
Z95.4 Presence of other heart-valve replacement
0.000 0.397 0.603
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.410 0.589
Z95.3 Presence of xenogenic heart valve
0.000 0.413 0.587
Z95.1 Presence of aortocoronary bypass graft
0.000 0.419 0.581
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.464 0.536
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.478 0.521
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.486 0.514
I22.8 Subsequent myocardial infarction of other sites
0.000 0.487 0.513
I24.1 Dressler's syndrome
0.000 0.529 0.471
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.547 0.453
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.547 0.453
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.547 0.453
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.547 0.453
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.547 0.453
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.547 0.453
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.547 0.453
I24.8 Other forms of acute ischaemic heart disease
0.000 0.561 0.439
Z95.2 Presence of prosthetic heart valve
0.000 0.592 0.408
I23.8 Other current complications following acute myocardial infarction
0.001 0.632 0.367
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.648 0.351
I20 Angina pectoris
0.000 0.657 0.343
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.663 0.337
I20.9 Angina pectoris, unspecified
0.000 0.714 0.286
Z95.0 Presence of cardiac pacemaker
0.000 0.722 0.278
Chapter IX Diseases of the circulatory system
0.000 0.799 0.201
I20.8 Other forms of angina pectoris
0.000 0.810 0.190
I10-I15 Hypertensive diseases
0.000 0.812 0.188
I10 Essential (primary) hypertension
0.000 0.819 0.181
I05-I09 Chronic rheumatic heart diseases
0.000 0.822 0.178
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.827 0.173
I73 Other peripheral vascular diseases
0.000 0.832 0.168
I20.1 Angina pectoris with documented spasm
0.000 0.832 0.168
I73.0 Raynaud's syndrome
0.000 0.838 0.162
C18.7 Sigmoid colon
0.150 0.850 0.000
I12 Hypertensive renal disease
0.000 0.852 0.148
I05 Rheumatic mitral valve diseases
0.000 0.852 0.148
I07 Rheumatic tricuspid valve diseases
0.000 0.853 0.147
I00-I02 Acute rheumatic fever
0.000 0.855 0.144
I08 Multiple valve diseases
0.000 0.858 0.142
I73.9 Peripheral vascular disease, unspecified
0.000 0.859 0.141
I12.9 Hypertensive renal disease without renal failure
0.000 0.863 0.137
I13 Hypertensive heart and renal disease
0.000 0.865 0.135
I74 Arterial embolism and thrombosis
0.000 0.866 0.134
I72 Other aneurysm
0.000 0.869 0.131
C18 Malignant neoplasm of colon
0.130 0.870 0.000
I11 Hypertensive heart disease
0.000 0.872 0.128
I06 Rheumatic aortic valve diseases
0.000 0.872 0.128
C71 Malignant neoplasm of brain
0.127 0.873 0.000
I05.0 Mitral stenosis
0.000 0.873 0.127
C50 Malignant neoplasm of breast
0.127 0.873 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.126 0.874 0.000
Chapter II Neoplasms
0.126 0.874 0.000
C50-C50 Malignant neoplasm of breast
0.126 0.874 0.000
I07.1 Tricuspid insufficiency
0.000 0.875 0.125
C15-C26 Malignant neoplasms of digestive organs
0.124 0.876 0.000
C51-C58 Malignant neoplasms of female genital organs
0.123 0.877 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.878 0.122
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.879 0.121
I73.8 Other specified peripheral vascular diseases
0.000 0.879 0.121
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.879 0.121
I15 Secondary hypertension
0.000 0.880 0.120
C50.5 Lower-outer quadrant of breast
0.120 0.880 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.881 0.119
I08.0 Disorders of both mitral and aortic valves
0.000 0.881 0.119
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.882 0.118
I09 Other rheumatic heart diseases
0.000 0.884 0.116
D00-D09 In situ neoplasms
0.115 0.885 0.000
C71.1 Frontal lobe
0.114 0.886 0.000
C56 Malignant neoplasm of ovary
0.114 0.886 0.000
C71.9 Brain, unspecified
0.114 0.886 0.000
I70 Atherosclerosis
0.000 0.887 0.113
C55 Malignant neoplasm of uterus, part unspecified
0.112 0.888 0.000
I71 Aortic aneurysm and dissection
0.000 0.888 0.112
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.888 0.112
C71.2 Temporal lobe
0.111 0.889 0.000
I05.1 Rheumatic mitral insufficiency
0.000 0.892 0.108
I78 Diseases of capillaries
0.000 0.892 0.108
I74.5 Embolism and thrombosis of iliac artery
0.000 0.893 0.107
C21 Malignant neoplasm of anus and anal canal
0.106 0.894 0.000
I05.8 Other mitral valve diseases
0.000 0.894 0.106
I05.2 Mitral stenosis with insufficiency
0.000 0.894 0.106
C18.6 Descending colon
0.106 0.894 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.106 0.894 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.106 0.894 0.000
I07.9 Tricuspid valve disease, unspecified
0.000 0.894 0.105
I07.8 Other tricuspid valve diseases
0.000 0.894 0.105
I07.2 Tricuspid stenosis with insufficiency
0.000 0.894 0.105
I07.0 Tricuspid stenosis
0.000 0.894 0.105
C50.3 Lower-inner quadrant of breast
0.104 0.895 0.000
I02 Rheumatic chorea
0.000 0.896 0.104
I01 Rheumatic fever with heart involvement
0.000 0.896 0.104
I00 Rheumatic fever without mention of heart involvement
0.000 0.896 0.104
C50.9 Breast, unspecified
0.102 0.898 0.000
I08.9 Multiple valve disease, unspecified
0.000 0.898 0.102
I05.9 Mitral valve disease, unspecified
0.000 0.898 0.102
I72.8 Aneurysm of other specified arteries
0.000 0.899 0.101
D05 Carcinoma in situ of breast
0.100 0.900 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.900 0.100
D03 Melanoma in situ
0.100 0.900 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.100 0.900 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.901 0.099
C17 Malignant neoplasm of small intestine
0.099 0.901 0.000
C50.2 Upper-inner quadrant of breast
0.099 0.901 0.000
C50.4 Upper-outer quadrant of breast
0.099 0.901 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.902 0.098
C71.8 Overlapping lesion of brain
0.098 0.902 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.098 0.902 0.000
C50.1 Central portion of breast
0.097 0.902 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.903 0.097
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.903 0.097
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.903 0.097
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.903 0.097
C54 Malignant neoplasm of corpus uteri
0.097 0.903 0.000
C18.2 Ascending colon
0.097 0.903 0.000
I72.3 Aneurysm of iliac artery
0.000 0.903 0.097
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.903 0.097
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.903 0.097
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.903 0.097
C69 Malignant neoplasm of eye and adnexa
0.096 0.904 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.904 0.096
C50.8 Overlapping lesion of breast
0.096 0.904 0.000
C71.3 Parietal lobe
0.096 0.904 0.000
I72.4 Aneurysm of artery of lower extremity
0.000 0.905 0.095
C18.0 Caecum
0.094 0.905 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.094 0.906 0.000
D04 Carcinoma in situ of skin
0.094 0.906 0.000
I72.9 Aneurysm of unspecified site
0.000 0.906 0.094
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.906 0.094
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.906 0.094
I72.2 Aneurysm of renal artery
0.000 0.906 0.094
I72.1 Aneurysm of artery of upper extremity
0.000 0.906 0.094
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.906 0.094
I99 Other and unspecified disorders of circulatory system
0.000 0.906 0.094
C18.8 Overlapping lesion of colon
0.093 0.907 0.000
C22.0 Liver cell carcinoma
0.093 0.907 0.000
D03.5 Melanoma in situ of trunk
0.093 0.907 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.092 0.908 0.000
C71.0 Cerebrum, except lobes and ventricles
0.092 0.908 0.000
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.908 0.092
I06.8 Other rheumatic aortic valve diseases
0.000 0.908 0.092
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.908 0.092
I06.1 Rheumatic aortic insufficiency
0.000 0.908 0.092
I06.0 Rheumatic aortic stenosis
0.000 0.908 0.092
C71.7 Brain stem
0.091 0.909 0.000
C71.6 Cerebellum
0.091 0.909 0.000
C71.5 Cerebral ventricle
0.091 0.909 0.000
C71.4 Occipital lobe
0.091 0.909 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.909 0.091
C97 Malignant neoplasms of independent (primary) multiple sites
0.091 0.909 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.091 0.909 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.909 0.091
C50.6 Axillary tail of breast
0.091 0.909 0.000
C23 Malignant neoplasm of gallbladder
0.091 0.909 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.091 0.909 0.000
C70 Malignant neoplasm of meninges
0.091 0.909 0.000
I72.0 Aneurysm of carotid artery
0.000 0.909 0.091
C18.1 Appendix
0.090 0.910 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.089 0.911 0.000
C51 Malignant neoplasm of vulva
0.089 0.911 0.000
C20 Malignant neoplasm of rectum
0.089 0.911 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.088 0.911 0.000
C58 Malignant neoplasm of placenta
0.088 0.911 0.000
C52 Malignant neoplasm of vagina
0.088 0.911 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.088 0.912 0.000
C21.1 Anal canal
0.087 0.912 0.000
C50.0 Nipple and areola
0.087 0.912 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.087 0.912 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.087 0.913 0.000
C18.9 Colon, unspecified
0.087 0.913 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.913 0.087
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.913 0.087
I79.1 Aortitis in diseases classified elsewhere
0.000 0.913 0.087
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.913 0.087
I15.9 Seconday hypertension, unspecified
0.000 0.913 0.086
I15.8 Other secondary hypertension
0.000 0.913 0.086
I15.2 Hypertension secondary to endocrine disorders
0.000 0.913 0.086
I15.0 Renovascular hypertension
0.000 0.913 0.086
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.914 0.086
C90 Multiple myeloma and malignant plasma cell neoplasms
0.085 0.914 0.000
I70.0 Atherosclerosis of aorta
0.000 0.915 0.085
C84 Peripheral and cutaneous T-cell lymphomas
0.085 0.915 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.915 0.085
I08.8 Other multiple valve diseases
0.000 0.915 0.084
D05.1 Intraductal carcinoma in situ
0.084 0.916 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.916 0.084
I09.8 Other specified rheumatic heart diseases
0.000 0.917 0.083
I09.2 Chronic rheumatic pericarditis
0.000 0.917 0.083
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.917 0.083
I09.0 Rheumatic myocarditis
0.000 0.917 0.083
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.083 0.917 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.082 0.917 0.000
C21.0 Anus, unspecified
0.082 0.918 0.000
C22.9 Liver, unspecified
0.081 0.919 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.081 0.919 0.000
I70.9 Generalised and unspecified atherosclerosis
0.000 0.919 0.081
I70.8 Atherosclerosis of other arteries
0.000 0.919 0.081
I70.1 Atherosclerosis of renal artery
0.000 0.919 0.081
C21.8 Overlapping lesion of rectum, anus and anal canal
0.081 0.919 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.081 0.919 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.919 0.080
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.919 0.080
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.919 0.080
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.919 0.080
C49.3 Connective and soft tissue of thorax
0.080 0.919 0.000
D04.6 Skin of upper limb, including shoulder
0.080 0.920 0.000
C26.9 Ill-defined sites within the digestive system
0.080 0.920 0.000
C64-C68 Malignant neoplasms of urinary tract
0.080 0.920 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.080 0.920 0.000
C90.0 Multiple myeloma
0.079 0.921 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.079 0.921 0.000
C54.1 Endometrium
0.079 0.921 0.000
I49.3 Ventricular premature depolarisation
0.000 0.922 0.078
D06 Carcinoma in situ of cervix uteri
0.078 0.922 0.000
I30-I52 Other forms of heart disease
0.000 0.922 0.078
D04.4 Skin of scalp and neck
0.078 0.922 0.000
I78.9 Disease of capillaries, unspecified
0.000 0.922 0.077
I74.8 Embolism and thrombosis of other arteries
0.000 0.923 0.077
C17.9 Small intestine, unspecified
0.076 0.923 0.000
C21.2 Cloacogenic zone
0.076 0.924 0.000
C22.7 Other specified carcinomas of liver
0.076 0.924 0.000
C22.4 Other sarcomas of liver
0.076 0.924 0.000
C22.3 Angiosarcoma of liver
0.076 0.924 0.000
C22.2 Hepatoblastoma
0.076 0.924 0.000
I49 Other cardiac arrhythmias
0.000 0.924 0.076
C17.2 Ileum
0.076 0.924 0.000
D41.4 Bladder
0.076 0.924 0.000
I97.1 Other functional disturbances following cardiac surgery
0.000 0.924 0.075
C18.4 Transverse colon
0.075 0.924 0.000
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.925 0.074
I01.8 Other acute rheumatic heart disease
0.000 0.925 0.074
I01.2 Acute rheumatic myocarditis
0.000 0.925 0.074
I01.1 Acute rheumatic endocarditis
0.000 0.925 0.074
I01.0 Acute rheumatic pericarditis
0.000 0.925 0.074
I02.9 Rheumatic chorea without heart involvement
0.000 0.925 0.074
I02.0 Rheumatic chorea with heart involvement
0.000 0.925 0.074
C18.3 Hepatic flexure
0.074 0.925 0.000
D01.3 Anus and anal canal
0.074 0.926 0.000
I78.8 Other diseases of capillaries
0.000 0.926 0.074
C84.0 Mycosis fungoides
0.074 0.926 0.000
D05.7 Other carcinoma in situ of breast
0.074 0.926 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.074 0.926 0.000
C69.3 Choroid
0.074 0.926 0.000
C18.5 Splenic flexure
0.073 0.927 0.000
I44 Atrioventricular and left bundle-branch block
0.000 0.927 0.073
C17.0 Duodenum
0.072 0.927 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.072 0.928 0.000
C88 Malignant immunoproliferative diseases
0.072 0.928 0.000
C53 Malignant neoplasm of cervix uteri
0.072 0.928 0.000
D03.9 Melanoma in situ, unspecified
0.072 0.928 0.000
D03.8 Melanoma in situ of other sites
0.072 0.928 0.000
D03.2 Melanoma in situ of ear and external auricular canal
0.072 0.928 0.000
D03.1 Melanoma in situ of eyelid, including canthus
0.072 0.928 0.000
D03.0 Melanoma in situ of lip
0.072 0.928 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.072 0.928 0.000
C46 Kaposi's sarcoma
0.072 0.928 0.000
D03.4 Melanoma in situ of scalp and neck
0.072 0.928 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.072 0.928 0.000
I15.1 Hypertension secondary to other renal disorders
0.000 0.929 0.071
I09.9 Rheumatic heart disease, unspecified
0.000 0.929 0.071
C17.8 Overlapping lesion of small intestine
0.071 0.929 0.000
C17.3 Meckel's diverticulum
0.071 0.929 0.000
C17.1 Jejunum
0.071 0.929 0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.071 0.929 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.071 0.929 0.000
C69.9 Eye, unspecified
0.070 0.929 0.000
C26.8 Overlapping lesion of digestive system
0.070 0.929 0.000
C26.1 Spleen
0.070 0.929 0.000
C92 Myeloid leukaemia
0.070 0.929 0.000
D09 Carcinoma in situ of other and unspecified sites
0.070 0.930 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.930 0.070
C54.8 Overlapping lesion of corpus uteri
0.070 0.930 0.000
C54.3 Fundus uteri
0.070 0.930 0.000
C54.2 Myometrium
0.070 0.930 0.000
C54.0 Isthmus uteri
0.070 0.930 0.000
C49.5 Connective and soft tissue of pelvis
0.070 0.930 0.000
I35 Nonrheumatic aortic valve disorders
0.000 0.930 0.070
I49.4 Other and unspecified premature depolarisation
0.000 0.931 0.069
I28 Other diseases of pulmonary vessels
0.000 0.931 0.069
C69.8 Overlapping lesion of eye and adnexa
0.069 0.931 0.000
C69.6 Orbit
0.069 0.931 0.000
C69.5 Lachrymal gland and duct
0.069 0.931 0.000
C69.4 Ciliary body
0.069 0.931 0.000
C69.2 Retina
0.069 0.931 0.000
C69.1 Cornea
0.069 0.931 0.000
C69.0 Conjunctiva
0.069 0.931 0.000
C22.1 Intrahepatic bile duct carcinoma
0.069 0.931 0.000
C26.0 Intestinal tract, part unspecified
0.069 0.931 0.000
C54.9 Corpus uteri, unspecified
0.069 0.931 0.000
D04.2 Skin of ear and external auricular canal
0.069 0.931 0.000
D04.5 Skin of trunk
0.069 0.931 0.000
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)
0.068 0.932 0.000
C40 Malignant neoplasm of bone and articular cartilage of limbs
0.068 0.932 0.000
D04.9 Skin, unspecified
0.068 0.932 0.000
D04.8 Skin of other sites
0.068 0.932 0.000
D04.1 Skin of eyelid, including canthus
0.068 0.932 0.000
D04.0 Skin of lip
0.068 0.932 0.000
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.932 0.067
I97.0 Postcardiotomy syndrome
0.000 0.932 0.067
C49.1 Connective and soft tissue of upper limb, including shoulder
0.067 0.933 0.000
C84.5 Other and unspecified T-cell lymphomas
0.067 0.933 0.000
C74 Malignant neoplasm of adrenal gland
0.067 0.933 0.000
I35.0 Aortic (valve) stenosis
0.000 0.933 0.067
D46 Myelodysplastic syndromes
0.067 0.933 0.000
C90.2 Plasmacytoma, extramedullary
0.067 0.933 0.000
C77.3 Axillary and upper limb lymph nodes
0.067 0.933 0.000
I44.7 Left bundle-branch block, unspecified
0.000 0.933 0.067
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.066 0.933 0.000
I36 Nonrheumatic tricuspid valve disorders
0.000 0.933 0.067
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.066 0.934 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.066 0.934 0.000
C95 Leukaemia of unspecified cell type
0.066 0.934 0.000
C94 Other leukaemias of specified cell type
0.066 0.934 0.000
C93 Monocytic leukaemia
0.066 0.934 0.000
C86 Other specified types of T/NK-cell lymphoma
0.066 0.934 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.066 0.934 0.000
I26 Pulmonary embolism
0.000 0.934 0.066
D01.9 Digestive organ, unspecified
0.066 0.934 0.000
D01.7 Other specified digestive organs
0.066 0.934 0.000
D01.5 Liver, gallbladder and bile ducts
0.066 0.934 0.000
D01.4 Other and unspecified parts of intestine
0.066 0.934 0.000
D01.2 Rectum
0.066 0.934 0.000
D01.1 Rectosigmoid junction
0.066 0.934 0.000
D01.0 Colon
0.066 0.934 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.066 0.934 0.000
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.934 0.065
C70.9 Meninges, unspecified
0.065 0.935 0.000
C70.1 Spinal meninges
0.065 0.935 0.000
C70.0 Cerebral meninges
0.065 0.935 0.000
C72.9 Central nervous system, unspecified
0.065 0.935 0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system
0.065 0.935 0.000
C72.5 Other and unspecified cranial nerves
0.065 0.935 0.000
C72.4 Acoustic nerve
0.065 0.935 0.000
C72.3 Optic nerve
0.065 0.935 0.000
C72.2 Olfactory nerve
0.065 0.935 0.000
C72.1 Cauda equina
0.065 0.935 0.000
C72.0 Spinal cord
0.065 0.935 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.935 0.065
C51.9 Vulva, unspecified
0.065 0.935 0.000
C65 Malignant neoplasm of renal pelvis
0.065 0.935 0.000
D03.7 Melanoma in situ of lower limb, including hip
0.064 0.936 0.000
C49.9 Connective and soft tissue, unspecified
0.064 0.936 0.000
C49.8 Overlapping lesion of connective and soft tissue
0.064 0.936 0.000
C49.6 Connective and soft tissue of trunk, unspecified
0.064 0.936 0.000
C49.4 Connective and soft tissue of abdomen
0.064 0.936 0.000
C49.0 Connective and soft tissue of head, face and neck
0.064 0.936 0.000
C51.8 Overlapping lesion of vulva
0.064 0.936 0.000
C51.2 Clitoris
0.064 0.936 0.000
C51.1 Labium minus
0.064 0.936 0.000
C51.0 Labium majus
0.064 0.936 0.000
I49.0 Ventricular fibrillation and flutter
0.000 0.936 0.064
I20.0 Unstable angina
0.000 0.936 0.064
C57.9 Female genital organ, unspecified
0.064 0.936 0.000
C57.8 Overlapping lesion of female genital organs
0.064 0.936 0.000
C57.7 Other specified female genital organs
0.064 0.936 0.000
C57.4 Uterine adnexa, unspecified
0.064 0.936 0.000
C57.3 Parametrium
0.064 0.936 0.000
C57.2 Round ligament
0.064 0.936 0.000
C57.1 Broad ligament
0.064 0.936 0.000
C57.0 Fallopian tube
0.064 0.936 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.063 0.937 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.937 0.063
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.063 0.937 0.000
C77.4 Inguinal and lower limb lymph nodes
0.062 0.938 0.000
D04.3 Skin of other and unspecified parts of face
0.062 0.938 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.062 0.938 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.062 0.938 0.000
C90.3 Solitary plasmacytoma
0.061 0.938 0.000
C90.1 Plasma cell leukaemia
0.061 0.938 0.000
C60-C63 Malignant neoplasms of male genital organs
0.061 0.938 0.000
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.939 0.061
C84.9 Mature T/NK-cell lymphoma, unspecified
0.061 0.939 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.061 0.939 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.061 0.939 0.000
C84.3 Lymphoepithelioid lymphoma
0.061 0.939 0.000
C84.2 T-zone lymphoma
0.061 0.939 0.000
C84.1 Sezary's diease
0.061 0.939 0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.939 0.061
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.939 0.061
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.939 0.061
I98.0 Cardiovascular syphilis
0.000 0.939 0.061
D07 Carcinoma in situ of other and unspecified genital organs
0.061 0.939 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.939 0.061
D48.1 Connective and other soft tissue
0.060 0.940 0.000
I44.0 Atrioventricular block, first degree
0.000 0.940 0.060
D03.3 Melanoma in situ of other and unspecified parts of face
0.060 0.940 0.000
C24.9 Biliary tract, unspecified
0.059 0.940 0.000
C24.8 Overlapping lesion of biliary tract
0.059 0.940 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.060 0.940 0.000
I44.6 Other and unspecified fascicular block
0.000 0.940 0.059
D00.2 Stomach
0.059 0.941 0.000
D00.1 Oesophagus
0.059 0.941 0.000
D00.0 Lip, oral cavity and pharynx
0.059 0.941 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.059 0.941 0.000
D05.0 Lobular carcinoma in situ
0.059 0.941 0.000
C24.1 Ampulla of Vater
0.059 0.941 0.000
C84.4 Peripheral T-cell lymphoma
0.059 0.941 0.000
D02.4 Respiratory system, unspecified
0.058 0.941 0.000
D02.3 Other parts of respiratory system
0.058 0.941 0.000
D02.2 Bronchus and lung
0.058 0.941 0.000
D02.1 Trachea
0.058 0.941 0.000
C15 Malignant neoplasm of oesophagus
0.059 0.941 0.000
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.942 0.058
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.942 0.058
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.942 0.058
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.942 0.058
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.942 0.058
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.942 0.058
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.942 0.058
C49.2 Connective and soft tissue of lower limb, including hip
0.058 0.942 0.000
C92.0 Acute myeloid leukaemia
0.058 0.942 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.058 0.942 0.000
D02.0 Larynx
0.057 0.943 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.057 0.943 0.000
D41.9 Urinary organ, unspecified
0.057 0.943 0.000
D41.7 Other urinary organs
0.057 0.943 0.000
D41.3 Urethra
0.057 0.943 0.000
D41.2 Ureter
0.057 0.943 0.000
D41.1 Renal pelvis
0.057 0.943 0.000
D38.1 Trachea, bronchus and lung
0.057 0.943 0.000
D06.7 Other parts of cervix
0.056 0.944 0.000
D06.1 Exocervix
0.056 0.944 0.000
D06.0 Endocervix
0.056 0.944 0.000
I37 Pulmonary valve disorders
0.000 0.944 0.056
I52 Other heart disorders in diseases classified elsewhere
0.000 0.944 0.056
I48 Atrial fibrillation and flutter
0.000 0.944 0.056
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.944 0.056
I41 Myocarditis in diseases classified elsewhere
0.000 0.944 0.056
I40 Acute myocarditis
0.000 0.944 0.056
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.944 0.056
I32 Pericarditis in diseases classified elsewhere
0.000 0.944 0.056
D38.0 Larynx
0.056 0.944 0.000
I44.1 Atrioventricular block, second degree
0.000 0.944 0.056
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.056 0.944 0.000
I71.0 Dissection of aorta [any part]
0.000 0.944 0.056
C73 Malignant neoplasm of thyroid gland
0.055 0.945 0.000
I77 Other disorders of arteries and arterioles
0.000 0.945 0.055
D04.7 Skin of lower limb, including hip
0.055 0.945 0.000
I47 Paroxysmal tachycardia
0.000 0.945 0.055
I49.2 Junctional premature depolarisation
0.000 0.945 0.055
C41.1 Mandible
0.055 0.945 0.000
I35.9 Aortic valve disorder, unspecified
0.000 0.945 0.054
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.054 0.946 0.000
C24.0 Extrahepatic bile duct
0.054 0.946 0.000
C81 Hodgkin's disease
0.054 0.946 0.000
C48.1 Specified parts of peritoneum
0.054 0.946 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.054 0.946 0.000
D48.6 Breast
0.053 0.947 0.000
D44.6 Carotid body
0.053 0.947 0.000
C77.0 Lymph nodes of head, face and neck
0.053 0.947 0.000
D46.2 Refractory anaemia with excess of blasts
0.053 0.947 0.000
I44.5 Left posterior fascicular block
0.000 0.948 0.052
I44.4 Left anterior fascicular block
0.000 0.948 0.052
C48.8 Overlapping lesion of retroperitoneum and peritoneum
0.052 0.948 0.000
C48.0 Retroperitoneum
0.052 0.948 0.000
D40.0 Prostate
0.052 0.948 0.000
C88.9 Malignant immunoproliferative disease, unspecified
0.052 0.948 0.000
C88.7 Other malignant immunoproliferative diseases
0.052 0.948 0.000
C88.3 Immunoproliferative small intestinal disease
0.052 0.948 0.000
C88.2 Gamma heavy chain disease
0.052 0.948 0.000
C88.1 Alpha heavy chain disease
0.052 0.948 0.000
C53.8 Overlapping lesion of cervix uteri
0.052 0.948 0.000
C53.1 Exocervix
0.052 0.948 0.000
C53.0 Endocervix
0.052 0.948 0.000
C74.9 Adrenal gland, unspecified
0.052 0.948 0.000
D06.9 Cervix, unspecified
0.052 0.948 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.052 0.948 0.000
C46.9 Kaposi's sarcoma, unspecified
0.052 0.948 0.000
C46.8 Kaposi's sarcoma of multiple organs
0.052 0.948 0.000
C46.7 Kaposi's sarcoma of other sites
0.052 0.948 0.000
C46.3 Kaposi's sarcoma of lymph nodes
0.052 0.948 0.000
C46.2 Kaposi's sarcoma of palate
0.052 0.948 0.000
C46.1 Kaposi's sarcoma of soft tissue
0.052 0.948 0.000
C46.0 Kaposi's sarcoma of skin
0.052 0.948 0.000
C47.9 Peripheral nerves and autonomic nervous system, unspecified
0.052 0.948 0.000
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system
0.052 0.948 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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