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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4416828
log Bayes Factor = 6.22936
Chromosome 8   position 24,468,982  (GRCh37) Explore rs4416828 on Ensembl!
Variant rs4416828 is part of Cluster X0141

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.997 0.003 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.996 0.004 0.000
Chapter VI Diseases of the nervous system
0.984 0.016 0.000
M45-M49 Spondylopathies
0.983 0.017 0.000
M65-M68 Disorders of synovium and tendon
0.974 0.026 0.000
M47 Spondylosis
0.974 0.026 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.974 0.026 0.000
S60-S69 Injuries to the wrist and hand
0.968 0.032 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.966 0.034 0.000
M40-M43 Deforming dorsopathies
0.963 0.037 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.963 0.037 0.000
S00-S09 Injuries to the head
0.960 0.040 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.950 0.050 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.950 0.050 0.000
Chapter II Neoplasms
0.949 0.051 0.000
M47.9 Spondylosis, unspecified
0.944 0.056 0.000
F10.3 Withdrawal state
0.944 0.056 0.000
F10.2 Dependence syndrome
0.942 0.058 0.000
E20-E35 Disorders of other endocrine glands
0.937 0.063 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.932 0.068 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.930 0.070 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.925 0.075 0.000
D50-D53 Nutritional anaemias
0.925 0.075 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.922 0.078 0.000
S00 Superficial injury of head
0.917 0.083 0.000
F10.0 Acute intoxication
0.916 0.084 0.000
S70-S79 Injuries to the hip and thigh
0.914 0.086 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.910 0.090 0.000
M65 Synovitis and tenosynovitis
0.905 0.095 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.905 0.095 0.000
G30-G32 Other degenerative diseases of the nervous system
0.903 0.097 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.900 0.100 0.000
G40-G47 Episodic and paroxysmal disorders
0.899 0.101 0.000
M67 Other disorders of synovium and tendon
0.899 0.101 0.000
S00.8 Superficial injury of other parts of head
0.893 0.107 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.893 0.107 0.000
M41 Scoliosis
0.883 0.117 0.000
M86-M90 Other osteopathies
0.880 0.120 0.000
S72 Fracture of femur
0.880 0.120 0.000
M47.8 Other spondylosis
0.878 0.122 0.000
T43.2 Other and unspecified antidepressants
0.876 0.124 0.000
F10.9 Unspecified mental and behavioural disorder
0.872 0.128 0.000
F30-F39 Mood [affective] disorders
0.871 0.129 0.000
M43 Other deforming dorsopathies
0.870 0.130 0.000
E65-E68 Obesity and other hyperalimentation
0.864 0.136 0.000
M05-M14 Inflammatory polyarthropathies
0.863 0.137 0.000
E23 Hypofunction and other disorders of pituitary gland
0.859 0.141 0.000
D80-D89 Certain disorders involving the immune mechanism
0.857 0.143 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.855 0.145 0.000
C83.0 Small cell (diffuse)
0.853 0.147 0.000
S62 Fracture at wrist and hand level
0.853 0.147 0.000
M47.2 Other spondylosis with radiculopathy
0.851 0.149 0.000
C50-C50 Malignant neoplasm of breast
0.850 0.150 0.000
Chapter XX External causes of morbidity and mortality
0.848 0.152 0.000
T90 Sequelae of injuries of head
0.845 0.155 0.000
M47.86 Other spondylosis (Lumbar region)
0.845 0.155 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.843 0.157 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.843 0.157 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.842 0.158 0.000
G90-G99 Other disorders of the nervous system
0.837 0.163 0.000
T93 Sequelae of injuries of lower limb
0.834 0.166 0.000
S69 Other and unspecified injuries of wrist and hand
0.834 0.166 0.000
D52 Folate deficiency anaemia
0.834 0.166 0.000
Chapter VIII Diseases of the ear and mastoid process
0.833 0.167 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.832 0.168 0.000
S72.1 Pertrochanteric fracture
0.830 0.170 0.000
S64 Injury of nerves at wrist and hand level
0.826 0.174 0.000
M41.9 Scoliosis, unspecified
0.826 0.174 0.000
F10.4 Withdrawal state with delirium
0.824 0.176 0.000
E22 Hyperfunction of pituitary gland
0.823 0.177 0.000
S09 Other and unspecified injuries of head
0.823 0.177 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.821 0.179 0.000
F60-F69 Disorders of adult personality and behaviour
0.821 0.179 0.000
T91 Sequelae of injuries of neck and trunk
0.821 0.179 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.820 0.179 0.000
E66 Obesity
0.819 0.181 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.812 0.188 0.000
M65.3 Trigger finger
0.811 0.189 0.000
D50 Iron deficiency anaemia
0.807 0.193 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.805 0.195 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.804 0.196 0.000
T00-T07 Injuries involving multiple body regions
0.802 0.198 0.000
F11 Mental and behavioural disorders due to use of opioids
0.802 0.198 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.799 0.200 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.799 0.201 0.000
E66.9 Obesity, unspecified
0.798 0.202 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.797 0.203 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.796 0.204 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.795 0.205 0.000
C90.2 Plasmacytoma, extramedullary
0.794 0.206 0.000
S72.10 Pertrochanteric fracture (closed)
0.794 0.206 0.000
E34 Other endocrine disorders
0.793 0.207 0.000
F00 Dementia in Alzheimer's disease
0.791 0.209 0.000
F33 Recurrent depressive disorder
0.791 0.209 0.000
M60-M63 Disorders of muscles
0.789 0.211 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.789 0.211 0.000
C90.0 Multiple myeloma
0.788 0.212 0.000
M43.1 Spondylolisthesis
0.787 0.213 0.000
S06 Intracranial injury
0.784 0.216 0.000
F10.6 Amnesic syndrome
0.782 0.218 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.781 0.219 0.000
S00.3 Superficial injury of nose
0.780 0.220 0.000
C50 Malignant neoplasm of breast
0.780 0.220 0.000
D50.8 Other iron deficiency anaemias
0.779 0.221 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.776 0.224 0.000
Q80-Q89 Other congenital malformations
0.775 0.225 0.000
M67.8 Other specified disorders of synovium and tendon
0.775 0.225 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.775 0.225 0.000
F10.5 Psychotic disorder
0.775 0.225 0.000
T98 Sequelae of other and unspecified effects of external causes
0.774 0.226 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.774 0.226 0.000
T90.9 Sequelae of unspecified injury of head
0.773 0.227 0.000
C50.4 Upper-outer quadrant of breast
0.773 0.227 0.000
T23 Burn and corrosion of wrist and hand
0.772 0.228 0.000
D52.9 Folate deficiency anaemia, unspecified
0.769 0.231 0.000
T79-T79 Certain early complications of trauma
0.769 0.231 0.000
D46 Myelodysplastic syndromes
0.768 0.232 0.000
C83.3 Large cell (diffuse)
0.765 0.235 0.000
M89 Other disorders of bone
0.765 0.235 0.000
S10-S19 Injuries to the neck
0.764 0.236 0.000
S50-S59 Injuries to the elbow and forearm
0.764 0.236 0.000
F03 Unspecified dementia
0.763 0.237 0.000
S20-S29 Injuries to the thorax
0.763 0.237 0.000
G47 Sleep disorders
0.758 0.242 0.000
E23.0 Hypopituitarism
0.754 0.246 0.000
G30 Alzheimer's disease
0.753 0.247 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.753 0.247 0.000
H80-H83 Diseases of inner ear
0.752 0.248 0.000
C95 Leukaemia of unspecified cell type
0.752 0.248 0.000
T31 Burns classified according to extent of body surface involved
0.751 0.249 0.000
E22.0 Acromegaly and pituitary gigantism
0.751 0.249 0.000
T93.2 Sequelae of other fractures of lower limb
0.749 0.251 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.748 0.252 0.000
D45 Polycythaemia vera
0.747 0.253 0.000
M65.34 Trigger finger-Hand
0.744 0.256 0.000
S61 Open wound of wrist and hand
0.744 0.256 0.000
G20-G26 Extrapyramidal and movement disorders
0.744 0.256 0.000
F70-F79 Mental retardation
0.743 0.257 0.000
C91 Lymphoid leukaemia
0.743 0.257 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.742 0.258 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.742 0.258 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.741 0.259 0.000
C85.1 B-cell lymphoma, unspecified
0.739 0.261 0.000
D86 Sarcoidosis
0.738 0.262 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.738 0.262 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.737 0.263 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.736 0.263 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.735 0.265 0.000
S05 Injury of eye and orbit
0.735 0.265 0.000
M49 Spondylopathies in diseases classified elsewhere
0.734 0.266 0.000
Chapter XXII Codes for special purposes
0.734 0.266 0.000
M05 Seropositive rheumatoid arthritis
0.731 0.269 0.000
E29 Testicular dysfunction
0.729 0.271 0.000
D48.5 Skin
0.726 0.274 0.000
D51 Vitamin B12 deficiency anaemia
0.726 0.274 0.000
S61.1 Open wound of finger(s) with damage to nail
0.724 0.276 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.724 0.276 0.000
E20 Hypoparathyroidism
0.723 0.277 0.000
T42.4 Benzodiazepines
0.723 0.277 0.000
S67 Crushing injury of wrist and hand
0.722 0.278 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.722 0.278 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.721 0.278 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.721 0.279 0.000
G96 Other disorders of central nervous system
0.721 0.279 0.000
F80-F89 Disorders of psychological development
0.720 0.280 0.000
E23.2 Diabetes insipidus
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
S40-S49 Injuries to the shoulder and upper arm
0.716 0.284 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.716 0.284 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.715 0.285 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.715 0.285 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.715 0.285 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.715 0.285 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.715 0.285 0.000
D00-D09 In situ neoplasms
0.714 0.286 0.000
F10.8 Other mental and behavioural disorders
0.714 0.286 0.000
F10.7 Residual and late-onset psychotic disorder
0.714 0.286 0.000
F01 Vascular dementia
0.714 0.286 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.714 0.286 0.000
M88 Paget's disease of bone [osteitis deformans]
0.714 0.286 0.000
G70-G73 Diseases of myoneural junction and muscle
0.713 0.287 0.000
S72.9 Fracture of femur, part unspecified
0.713 0.287 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.712 0.288 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.711 0.289 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.710 0.290 0.000
M67.0 Short Achilles tendon (acquired)
0.710 0.290 0.000
G45.4 Transient global amnesia
0.710 0.290 0.000
F02 Dementia in other diseases classified elsewhere
0.708 0.292 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.708 0.292 0.000
S69.9 Unspecified injury of wrist and hand
0.706 0.293 0.000
E24 Cushing's syndrome
0.706 0.294 0.000
G90 Disorders of autonomic nervous system
0.706 0.294 0.000
M66 Spontaneous rupture of synovium and tendon
0.705 0.295 0.000
C88 Malignant immunoproliferative diseases
0.703 0.297 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.703 0.297 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.703 0.297 0.000
S09.9 Unspecified injury of head
0.703 0.297 0.000
S00.5 Superficial injury of lip and oral cavity
0.702 0.298 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.702 0.298 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.702 0.298 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.701 0.298 0.000
M40 Kyphosis and lordosis
0.701 0.299 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.700 0.300 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.698 0.302 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.698 0.302 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.698 0.302 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.698 0.302 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.698 0.302 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.698 0.302 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.698 0.302 0.000
T36 Poisoning by systemic antibiotics
0.698 0.302 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.698 0.302 0.000
F30 Manic episode
0.698 0.302 0.000
M89.9 Disorder of bone, unspecified
0.697 0.303 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.696 0.304 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.696 0.304 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.696 0.304 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.695 0.305 0.000
M91-M94 Chondropathies
0.695 0.305 0.000
V10-V19 Pedal cyclist injured in transport accident
0.694 0.306 0.000
S65 Injury of blood vessels at wrist and hand level
0.694 0.306 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.694 0.306 0.000
S90-S99 Injuries to the ankle and foot
0.694 0.306 0.000
M50-M54 Other dorsopathies
0.692 0.308 0.000
M06 Other rheumatoid arthritis
0.692 0.308 0.000
D84 Other immunodeficiencies
0.692 0.308 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.691 0.309 0.000
D39.1 Ovary
0.691 0.309 0.000
M42 Spinal osteochondrosis
0.690 0.309 0.000
S00.7 Multiple superficial injuries of head
0.690 0.310 0.000
T95 Sequelae of burns, corrosions and frostbite
0.690 0.310 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.690 0.310 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.690 0.310 0.000
X60-X84 Intentional self-harm
0.690 0.310 0.000
S62.6 Fracture of other finger
0.690 0.310 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.690 0.310 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.689 0.311 0.000
W00-W19 Falls
0.689 0.311 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.688 0.312 0.000
S08 Traumatic amputation of part of head
0.688 0.312 0.000
S07 Crushing injury of head
0.688 0.312 0.000
S04 Injury of cranial nerves
0.688 0.312 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.688 0.312 0.000
M15-M19 Arthrosis
0.688 0.312 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.687 0.313 0.000
M11 Other crystal arthropathies
0.686 0.314 0.000
M87 Osteonecrosis
0.686 0.314 0.000
D60-D64 Aplastic and other anaemias
0.685 0.315 0.000
M46 Other inflammatory spondylopathies
0.685 0.315 0.000
S06.0 Concussion
0.685 0.315 0.000
S72.4 Fracture of lower end of femur
0.685 0.315 0.000
M00-M03 Infectious arthropathies
0.684 0.316 0.000
E27 Other disorders of adrenal gland
0.683 0.317 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.683 0.317 0.000
F99-F99 Unspecified mental disorder
0.683 0.317 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.682 0.318 0.000
M10 Gout
0.682 0.318 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.681 0.319 0.000
C94 Other leukaemias of specified cell type
0.681 0.319 0.000
C93 Monocytic leukaemia
0.681 0.319 0.000
C86 Other specified types of T/NK-cell lymphoma
0.681 0.319 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.680 0.320 0.000
G31.2 Degeneration of nervous system due to alcohol
0.680 0.320 0.000
M48 Other spondylopathies
0.680 0.320 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.680 0.320 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.680 0.320 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.679 0.321 0.000
S29 Other and unspecified injuries of thorax
0.679 0.321 0.000
D48.1 Connective and other soft tissue
0.679 0.321 0.000
H81 Disorders of vestibular function
0.678 0.322 0.000
S72.8 Fractures of other parts of femur
0.678 0.322 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.677 0.323 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.677 0.323 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.677 0.323 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.677 0.323 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.677 0.323 0.000
T31.0 Burns involving less than 10% of body surface
0.676 0.324 0.000
Q82 Other congenital malformations of skin
0.676 0.324 0.000
M43.0 Spondylolysis
0.675 0.324 0.000
H65-H75 Diseases of middle ear and mastoid
0.675 0.325 0.000
D53 Other nutritional anaemias
0.674 0.325 0.000
S68 Traumatic amputation of wrist and hand
0.673 0.327 0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)
0.672 0.328 0.000
F60 Specific personality disorders
0.672 0.328 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.672 0.328 0.000
T21 Burn and corrosion of trunk
0.672 0.328 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.671 0.328 0.000
E32 Diseases of thymus
0.671 0.328 0.000
E31 Polyglandular dysfunction
0.671 0.328 0.000
E30 Disorders of puberty, not elsewhere classified
0.671 0.328 0.000
E25 Adrenogenital disorders
0.671 0.328 0.000
S71 Open wound of hip and thigh
0.671 0.329 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.671 0.329 0.000
M65.8 Other synovitis and tenosynovitis
0.670 0.329 0.000
T43.9 Psychotropic drug, unspecified
0.668 0.332 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.668 0.332 0.000
T43.6 Psychostimulants with abuse potential
0.668 0.332 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.668 0.332 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.668 0.332 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.667 0.332 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.666 0.334 0.000
C81 Hodgkin's disease
0.666 0.334 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.666 0.334 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.666 0.334 0.000
T20 Burn and corrosion of head and neck
0.665 0.335 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.665 0.335 0.000
M65.1 Other infective (teno)synovitis
0.665 0.335 0.000
E28 Ovarian dysfunction
0.665 0.335 0.000
S72.3 Fracture of shaft of femur
0.665 0.335 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.663 0.336 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.663 0.336 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.663 0.336 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.663 0.337 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.663 0.337 0.000
F11.2 Dependence syndrome
0.662 0.338 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.662 0.338 0.000
G95 Other diseases of spinal cord
0.662 0.338 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.661 0.339 0.000
C83.7 Burkitt's tumour
0.661 0.339 0.000
C83.6 Undifferentiated (diffuse)
0.661 0.339 0.000
C83.5 Lymphoblastic (diffuse)
0.661 0.339 0.000
C83.4 Immunoblastic (diffuse)
0.661 0.339 0.000
C83.2 Mixed small and large cell (diffuse)
0.661 0.339 0.000
C83.1 Small cleaved cell (diffuse)
0.661 0.339 0.000
Y00-Y09 Assault
0.660 0.340 0.000
T91.3 Sequelae of injury of spinal cord
0.659 0.341 0.000
S62.2 Fracture of first metacarpal bone
0.659 0.341 0.000
T40.2 Other opioids
0.658 0.342 0.000
S00.1 Contusion of eyelid and periocular area
0.658 0.342 0.000
S00.4 Superficial injury of ear
0.657 0.342 0.000
S69.8 Other specified injuries of wrist and hand
0.657 0.343 0.000
G41 Status epilepticus
0.656 0.344 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.656 0.344 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.656 0.344 0.000
S64.1 Injury of median nerve at wrist and hand level
0.656 0.344 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.656 0.344 0.000
S78 Traumatic amputation of hip and thigh
0.655 0.344 0.000
S77 Crushing injury of hip and thigh
0.655 0.344 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.655 0.344 0.000
S75 Injury of blood vessels at hip and thigh level
0.655 0.344 0.000
S74 Injury of nerves at hip and thigh level
0.655 0.344 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.655 0.344 0.000
X10-X19 Contact with heat and hot substances
0.655 0.345 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.655 0.345 0.000
E34.9 Endocrine disorder, unspecified
0.655 0.345 0.000
Q38.7 Pharyngeal pouch
0.654 0.346 0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)
0.653 0.346 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.652 0.348 0.000
Q35-Q37 Cleft lip and cleft palate
0.652 0.348 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.652 0.348 0.000
C92 Myeloid leukaemia
0.652 0.348 0.000
D55-D59 Haemolytic anaemias
0.651 0.349 0.000
Q50-Q56 Congenital malformations of genital organs
0.651 0.349 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.650 0.350 0.000
S64.3 Injury of digital nerve of thumb
0.649 0.350 0.000
M65.2 Calcific tendinitis
0.649 0.351 0.000
M65.0 Abscess of tendon sheath
0.649 0.351 0.000
G44 Other headache syndromes
0.649 0.351 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.649 0.351 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.649 0.351 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.649 0.351 0.000
F09 Unspecified organic or symptomatic mental disorder
0.649 0.351 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.649 0.351 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.647 0.352 0.000
E10-E14 Diabetes mellitus
0.646 0.354 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.645 0.354 0.000
T25 Burn and corrosion of ankle and foot
0.645 0.355 0.000
G30.9 Alzheimer's disease, unspecified
0.645 0.355 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.645 0.355 0.000
M67.9 Disorder of synovium and tendon, unspecified
0.644 0.355 0.000
M67.4 Ganglion
0.644 0.355 0.000
M67.3 Transient synovitis
0.644 0.355 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.642 0.358 0.000
F31 Bipolar affective disorder
0.642 0.358 0.000
C90.3 Solitary plasmacytoma
0.640 0.360 0.000
C90.1 Plasma cell leukaemia
0.640 0.360 0.000
G47.9 Sleep disorder, unspecified
0.640 0.360 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.639 0.361 0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified
0.639 0.361 0.000
E23.6 Other disorders of pituitary gland
0.638 0.362 0.000
G96.0 Cerebrospinal fluid leak
0.637 0.363 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.637 0.363 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.636 0.364 0.000
D37.1 Stomach
0.636 0.364 0.000
T42.1 Iminostilbenes
0.635 0.365 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.635 0.365 0.000
S50 Superficial injury of forearm
0.634 0.366 0.000
M41.8 Other forms of scoliosis
0.633 0.367 0.000
M41.5 Other secondary scoliosis
0.633 0.367 0.000
M41.4 Neuromuscular scoliosis
0.633 0.367 0.000
M41.3 Thoracogenic scoliosis
0.633 0.367 0.000
M41.2 Other idiopathic scoliosis
0.633 0.367 0.000
M41.1 Juvenile idiopathic scoliosis
0.633 0.367 0.000
M41.0 Infantile idiopathic scoliosis
0.633 0.367 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.633 0.367 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.632 0.368 0.000
D37.3 Appendix
0.632 0.368 0.000
S09.8 Other specified injuries of head
0.632 0.368 0.000
S72.7 Multiple fractures of femur
0.631 0.369 0.000
F33.9 Recurrent depressive disorder, unspecified
0.631 0.369 0.000
S72.2 Subtrochanteric fracture
0.630 0.369 0.000
T23.0 Burn of unspecified degree of wrist and hand
0.630 0.369 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.630 0.370 0.000
T91.2 Sequelae of other fracture of thorax and pelvis
0.630 0.370 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.630 0.370 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.630 0.370 0.000
M47.84 Other spondylosis (Thoracic region)
0.630 0.370 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.630 0.370 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.630 0.370 0.000
T90.8 Sequelae of other specified injuries of head
0.628 0.371 0.000
E34.8 Other specified endocrine disorders
0.627 0.373 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.626 0.374 0.000
S06.8 Other intracranial injuries
0.626 0.374 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.626 0.374 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.626 0.374 0.000
C50.5 Lower-outer quadrant of breast
0.626 0.374 0.000
E26 Hyperaldosteronism
0.625 0.374 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.626 0.374 0.000
F38 Other mood [affective] disorders
0.625 0.375 0.000
F34 Persistent mood [affective] disorders
0.625 0.375 0.000
F39 Unspecified mood [affective] disorder
0.625 0.375 0.000
T02 Fractures involving multiple body regions
0.625 0.375 0.000
M14 Arthropathies in other diseases classified elsewhere
0.624 0.376 0.000
M43.9 Deforming dorsopathy, unspecified
0.624 0.376 0.000
M43.8 Other specified deforming dorsopathies
0.624 0.376 0.000
M43.6 Torticollis
0.624 0.376 0.000
M43.5 Other recurrent vertebral subluxation
0.624 0.376 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.624 0.376 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.624 0.376 0.000
M43.2 Other fusion of spine
0.624 0.376 0.000
D03 Melanoma in situ
0.624 0.376 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.623 0.377 0.000
T90.5 Sequelae of intracranial injury
0.622 0.378 0.000
S12 Fracture of neck
0.622 0.378 0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)
0.622 0.378 0.000
S64.4 Injury of digital nerve of other finger
0.621 0.378 0.000
F64 Gender identity disorders
0.621 0.379 0.000
T91.1 Sequelae of fracture of spine
0.621 0.379 0.000
M19 Other arthrosis
0.621 0.379 0.000
T00 Superficial injuries involving multiple body regions
0.621 0.379 0.000
G25 Other extrapyramidal and movement disorders
0.620 0.380 0.000
D48.0 Bone and articular cartilage
0.620 0.380 0.000
E67 Other hyperalimentation
0.619 0.380 0.000
E68 Sequelae of hyperalimentation
0.619 0.380 0.000
D80 Immunodeficiency with predominantly antibody defects
0.619 0.381 0.000
M45 Ankylosing spondylitis
0.619 0.381 0.000
M51 Other intervertebral disk disorders
0.619 0.381 0.000
M12 Other specific arthropathies
0.619 0.381 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.619 0.381 0.000
M08 Juvenile arthritis
0.619 0.381 0.000
S29.9 Unspecified injury of thorax
0.619 0.381 0.000
D62 Acute posthaemorrhagic anaemia
0.619 0.381 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.618 0.382 0.000
M62 Other disorders of muscle
0.617 0.383 0.000
E23.7 Disorder of pituitary gland, unspecified
0.616 0.384 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.616 0.384 0.000
E23.1 Drug-induced hypopituitarism
0.616 0.384 0.000
Q39 Congenital malformations of oesophagus
0.616 0.384 0.000
F19.1 Harmful use
0.616 0.384 0.000
D37.0 Lip, oral cavity and pharynx
0.615 0.385 0.000
V20-V29 Motorcycle rider injured in transport accident
0.615 0.385 0.000
Y85 Sequelae of transport accidents
0.615 0.385 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.615 0.385 0.000
H83 Other diseases of inner ear
0.615 0.385 0.000
G62 Other polyneuropathies
0.614 0.386 0.000
D83 Common variable immunodeficiency
0.614 0.386 0.000
D82 Immunodeficiency associated with other major defects
0.614 0.386 0.000
D81 Combined immunodeficiencies
0.614 0.386 0.000
S06.00 Concussion (without open intracranial wound)
0.614 0.386 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.614 0.386 0.000
M80-M85 Disorders of bone density and structure
0.613 0.387 0.000
T32 Corrosions classified according to extent of body surface involved
0.613 0.387 0.000
T30 Burn and corrosion, body region unspecified
0.613 0.387 0.000
T29 Burns and corrosions of multiple body regions
0.613 0.387 0.000
D86.0 Sarcoidosis of lung
0.612 0.388 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.611 0.388 0.000
S62.7 Multiple fractures of fingers
0.611 0.389 0.000
S62.1 Fracture of other carpal bone(s)
0.611 0.389 0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)
0.610 0.390 0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)
0.610 0.390 0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)
0.610 0.390 0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)
0.610 0.390 0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)
0.610 0.390 0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)
0.610 0.390 0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)
0.610 0.390 0.000
C95.9 Leukaemia, unspecified
0.610 0.390 0.000
X50-X57 Overexertion, travel and privation
0.610 0.390 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.609 0.391 0.000
E40-E46 Malnutrition
0.609 0.391 0.000
H74 Other disorders of middle ear and mastoid
0.609 0.391 0.000
Y35-Y36 Legal intervention and operations of war
0.608 0.392 0.000
Y10-Y34 Event of undetermined intent
0.608 0.392 0.000
X85-X99 Assault
0.608 0.392 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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