TreeWAS – Variant ID: rs5744807

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.999	0.001
N18 Chronic renal failure	0.997	0.003
N17-N19 Renal failure	0.997	0.003
Chapter X Diseases of the respiratory system	0.997	0.003
Chapter XIV Diseases of the genitourinary system	0.996	0.004
E10-E14 Diabetes mellitus	0.995	0.005
I30-I52 Other forms of heart disease	0.995	0.005
J40-J47 Chronic lower respiratory diseases	0.995	0.005
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.994	0.006
I25 Chronic ischaemic heart disease	0.993	0.007
J44 Other chronic obstructive pulmonary disease	0.991	0.009
I35 Nonrheumatic aortic valve disorders	0.990	0.010
I21 Acute myocardial infarction	0.988	0.012
J44.9 Chronic obstructive pulmonary disease, unspecified	0.985	0.015
I35.0 Aortic (valve) stenosis	0.985	0.015
I70-I79 Diseases of arteries, arterioles and capillaries	0.983	0.017
N18.9 Chronic renal failure, unspecified	0.981	0.019
S60-S69 Injuries to the wrist and hand	0.978	0.022
I22 Subsequent myocardial infarction	0.978	0.022
Chapter VI Diseases of the nervous system	0.976	0.024
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.971	0.029
E11 Non-insulin-dependent diabetes mellitus	0.971	0.029
E20-E35 Disorders of other endocrine glands	0.967	0.033
I25.9 Chronic ischaemic heart disease, unspecified	0.967	0.033
G62 Other polyneuropathies	0.955	0.045
I21.9 Acute myocardial infarction, unspecified	0.954	0.046
Chapter XXII Codes for special purposes	0.952	0.048
E10 Insulin-dependent diabetes mellitus	0.951	0.049
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.949	0.051
N18.5 Chronic kidney disease, stage 5	0.948	0.052
I73 Other peripheral vascular diseases	0.948	0.052
N00-N08 Glomerular diseases	0.947	0.053
N18.4 Chronic kidney disease, stage 4	0.947	0.053
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.939	0.061
I22.9 Subsequent myocardial infarction of unspecified site	0.938	0.062
I21.4 Acute subendocardial myocardial infarction	0.933	0.067
G62.9 Polyneuropathy, unspecified	0.933	0.067
E11.2 With renal complications	0.932	0.068
Chapter XX External causes of morbidity and mortality	0.930	0.070
I50 Heart failure	0.927	0.073
S00-S09 Injuries to the head	0.923	0.077
J42 Unspecified chronic bronchitis	0.920	0.080
N08 Glomerular disorders in diseases classified elsewhere	0.911	0.089
S68 Traumatic amputation of wrist and hand	0.911	0.089
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.906	0.094
S00 Superficial injury of head	0.899	0.101
M15-M19 Arthrosis	0.899	0.101
I73.9 Peripheral vascular disease, unspecified	0.899	0.101
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.895	0.105
J43 Emphysema	0.895	0.105
M19 Other arthrosis	0.893	0.107
S62 Fracture at wrist and hand level	0.892	0.108
I05-I09 Chronic rheumatic heart diseases	0.888	0.112
N17 Acute renal failure	0.887	0.113
N08.3 Glomerular disorders in diabetes mellitus	0.881	0.119
J95-J99 Other diseases of the respiratory system	0.876	0.124
I22.0 Subsequent myocardial infarction of anterior wall	0.870	0.130
M19.9 Arthrosis, unspecified	0.868	0.132
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.867	0.133
N18.0 End-stage renal disease	0.867	0.133
S00.0 Superficial injury of scalp	0.866	0.134
I10-I15 Hypertensive diseases	0.863	0.137
I72 Other aneurysm	0.863	0.137
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.862	0.138
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.861	0.139
G80-G83 Cerebral palsy and other paralytic syndromes	0.860	0.140
E11.5 With peripheral circulatory complications	0.858	0.142
I25.8 Other forms of chronic ischaemic heart disease	0.856	0.144
I50.1 Left ventricular failure	0.854	0.146
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.850	0.150
E10.9 Without complications	0.850	0.150
Q20-Q28 Congenital malformations of the circulatory system	0.847	0.153
T15-T19 Effects of foreign body entering through natural orifice	0.846	0.154
E22 Hyperfunction of pituitary gland	0.845	0.155
G61 Inflammatory polyneuropathy	0.842	0.158
U80 Agent resistant to penicillin and related antibiotics	0.841	0.159
M19.94 Arthrosis, unspecified (Hand)	0.839	0.161
I12 Hypertensive renal disease	0.839	0.161
I35.9 Aortic valve disorder, unspecified	0.839	0.161
I60-I69 Cerebrovascular diseases	0.835	0.165
T66-T78 Other and unspecified effects of external causes	0.834	0.166
Y60-Y69 Misadventures to patients during surgical and medical care	0.834	0.166
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.825	0.175
I12.0 Hypertensive renal disease with renal failure	0.824	0.176
M05-M14 Inflammatory polyarthropathies	0.823	0.177
J46 Status asthmaticus	0.823	0.177
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.823	0.177
I70 Atherosclerosis	0.819	0.181
E11.4 With neurological complications	0.818	0.182
I51 Complications and ill-defined descriptions of heart disease	0.816	0.184
Y52 Agents primarily affecting the cardiovascular system	0.815	0.185
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.815	0.185
J43.9 Emphysema, unspecified	0.814	0.186
E10.4 With neurological complications	0.814	0.186
S60 Superficial injury of wrist and hand	0.814	0.186
I42 Cardiomyopathy	0.814	0.186
N18.3 Chronic kidney disease, stage 3	0.812	0.188
I08 Multiple valve diseases	0.809	0.191
N17.9 Acute renal failure, unspecified	0.808	0.192
G62.0 Drug-induced polyneuropathy	0.807	0.193
I44 Atrioventricular and left bundle-branch block	0.804	0.196
I37 Pulmonary valve disorders	0.802	0.198
G83 Other paralytic syndromes	0.799	0.201
E50-E64 Other nutritional deficiencies	0.797	0.203
I25.0 Atherosclerotic cardiovascular disease, so described	0.797	0.203
E10.5 With peripheral circulatory complications	0.797	0.203
I25.3 Aneurysm of heart	0.796	0.203
I25.5 Ischaemic cardiomyopathy	0.795	0.205
G70-G73 Diseases of myoneural junction and muscle	0.795	0.205
I31 Other diseases of pericardium	0.792	0.208
M19.0 Primary arthrosis of other joints	0.791	0.208
T20-T25 Burns and corrosions of external body surface, specified by site	0.791	0.209
Chapter XII Diseases of the skin and subcutaneous tissue	0.791	0.209
S00.3 Superficial injury of nose	0.790	0.210
E13 Other specified diabetes mellitus	0.790	0.210
J60-J70 Lung diseases due to external agents	0.789	0.211
I72.0 Aneurysm of carotid artery	0.789	0.211
G60 Hereditary and idiopathic neuropathy	0.789	0.211
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.788	0.212
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.788	0.212
I35.8 Other aortic valve disorders	0.787	0.213
E11.1 With ketoacidosis	0.785	0.215
S62.7 Multiple fractures of fingers	0.783	0.217
D68 Other coagulation defects	0.782	0.218
G63 Polyneuropathy in diseases classified elsewhere	0.781	0.219
E28 Ovarian dysfunction	0.781	0.219
I74 Arterial embolism and thrombosis	0.780	0.220
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.777	0.223
Q38-Q45 Other congenital malformations of the digestive system	0.775	0.225
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.775	0.225
J30-J39 Other diseases of upper respiratory tract	0.775	0.225
I21.1 Acute transmural myocardial infarction of inferior wall	0.773	0.227
N60-N64 Disorders of breast	0.772	0.228
M45-M49 Spondylopathies	0.772	0.228
J95 Postprocedural respiratory disorders, not elsewhere classified	0.771	0.229
I44.0 Atrioventricular block, first degree	0.770	0.230
I73.0 Raynaud's syndrome	0.770	0.230
J09-J18 Influenza and pneumonia	0.768	0.232
E40-E46 Malnutrition	0.768	0.232
I21.2 Acute transmural myocardial infarction of other sites	0.768	0.232
N18.2 Chronic kidney disease, stage 2	0.766	0.234
S05 Injury of eye and orbit	0.766	0.234
I25.1 Atherosclerotic heart disease	0.765	0.235
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.765	0.235
E23 Hypofunction and other disorders of pituitary gland	0.764	0.235
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.764	0.236
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.763	0.237
M60-M63 Disorders of muscles	0.762	0.238
T00-T07 Injuries involving multiple body regions	0.762	0.238
M06 Other rheumatoid arthritis	0.762	0.238
I20 Angina pectoris	0.762	0.238
S65 Injury of blood vessels at wrist and hand level	0.761	0.239
L00-L08 Infections of the skin and subcutaneous tissue	0.761	0.239
S62.6 Fracture of other finger	0.758	0.242
I08.1 Disorders of both mitral and tricuspid valves	0.758	0.242
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.758	0.242
S20-S29 Injuries to the thorax	0.756	0.244
S66 Injury of muscle and tendon at wrist and hand level	0.755	0.245
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.755	0.245
E29 Testicular dysfunction	0.752	0.247
M19.98 Arthrosis, unspecified (Other)	0.752	0.248
I25.4 Coronary artery aneurysm	0.752	0.248
G30-G32 Other degenerative diseases of the nervous system	0.751	0.249
I67 Other cerebrovascular diseases	0.750	0.250
G00-G09 Inflammatory diseases of the central nervous system	0.749	0.251
N18.8 Other chronic renal failure	0.748	0.251
U80.1 Methicillin resistant agent	0.749	0.251
I50.9 Heart failure, unspecified	0.746	0.254
S80-S89 Injuries to the knee and lower leg	0.745	0.255
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.744	0.256
M19.90 Arthrosis, unspecified (Multiple sites)	0.744	0.256
S61 Open wound of wrist and hand	0.741	0.259
I73.8 Other specified peripheral vascular diseases	0.740	0.260
J80-J84 Other respiratory diseases principally affecting the interstitium	0.739	0.260
G61.0 Guillain-Barre syndrome	0.739	0.261
E14 Unspecified diabetes mellitus	0.738	0.262
E22.1 Hyperprolactinaemia	0.736	0.264
M19.1 Posttraumatic arthrosis of other joints	0.735	0.265
Y52.4 Angiotensin-converting-enzyme inhibitors	0.735	0.265
T81 Complications of procedures, not elsewhere classified	0.735	0.265
E21.0 Primary hyperparathyroidism	0.735	0.265
I33 Acute and subacute endocarditis	0.734	0.266
I27 Other pulmonary heart diseases	0.732	0.267
E10.2 With renal complications	0.729	0.271
U80.0 Penicillin resistant agent	0.729	0.271
S01 Open wound of head	0.729	0.271
N60 Benign mammary dysplasia	0.728	0.272
S00.5 Superficial injury of lip and oral cavity	0.724	0.276
Y00-Y09 Assault	0.723	0.277
J34 Other disorders of nose and nasal sinuses	0.721	0.279
T18 Foreign body in alimentary tract	0.718	0.282
I00-I02 Acute rheumatic fever	0.717	0.283
S50-S59 Injuries to the elbow and forearm	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.717	0.283
D68.2 Hereditary deficiency of other clotting factors	0.716	0.284
Y60.0 During surgical operation	0.716	0.284
Y83.2 Surgical operation with anastomosis, bypass or graft	0.715	0.285
N18.1 Chronic kidney disease, stage 1	0.715	0.285
E12 Malnutrition-related diabetes mellitus	0.713	0.286
E21.3 Hyperparathyroidism, unspecified	0.713	0.286
I52 Other heart disorders in diseases classified elsewhere	0.713	0.287
I48 Atrial fibrillation and flutter	0.713	0.287
I43 Cardiomyopathy in diseases classified elsewhere	0.713	0.287
I41 Myocarditis in diseases classified elsewhere	0.713	0.287
I40 Acute myocarditis	0.713	0.287
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.713	0.287
I36 Nonrheumatic tricuspid valve disorders	0.713	0.287
I32 Pericarditis in diseases classified elsewhere	0.713	0.287
J41 Simple and mucopurulent chronic bronchitis	0.713	0.287
I46 Cardiac arrest	0.713	0.287
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.713	0.287
T33-T35 Frostbite	0.712	0.287
T26-T28 Burns and corrosions confined to eye and internal organs	0.712	0.287
I25.6 Silent myocardial ischaemia	0.712	0.288
X60-X84 Intentional self-harm	0.711	0.289
L08 Other local infections of skin and subcutaneous tissue	0.711	0.289
N99-N99 Other disorders of the genitourinary system	0.710	0.290
M80-M85 Disorders of bone density and structure	0.710	0.290
I21.X Presumed acute myicardial infaction (unconfirmed)	0.708	0.292
I21.3 Acute transmural myocardial infarction of unspecified site	0.708	0.292
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.708	0.292
W50-W64 Exposure to animate mechanical forces	0.707	0.293
I22.1 Subsequent myocardial infarction of inferior wall	0.707	0.293
U51 Admission status on psychiatric patients	0.707	0.293
M19.99 Arthrosis, unspecified (Site unspecified)	0.706	0.294
N02 Recurrent and persistent haematuria	0.706	0.294
M06.9 Rheumatoid arthritis, unspecified	0.705	0.295
M19.2 Other secondary arthrosis	0.705	0.295
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.704	0.296
S62.70 Multiple fractures of fingers (closed)	0.704	0.296
S90-S99 Injuries to the ankle and foot	0.702	0.298
E11.3 With ophthalmic complications	0.702	0.298
I70.2 Atherosclerosis of arteries of the extremities	0.701	0.299
S10-S19 Injuries to the neck	0.701	0.299
M86-M90 Other osteopathies	0.700	0.300
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.700	0.300
M91-M94 Chondropathies	0.699	0.301
S67 Crushing injury of wrist and hand	0.699	0.301
I20.9 Angina pectoris, unspecified	0.697	0.303
I31.3 Pericardial effusion (noninflammatory)	0.697	0.303
J95.8 Other postprocedural respiratory disorders	0.697	0.303
G64 Other disorders of peripheral nervous system	0.696	0.303
I62 Other nontraumatic intracranial haemorrhage	0.696	0.304
J18 Pneumonia, organism unspecified	0.696	0.304
E11.8 With unspecified complications	0.696	0.304
E11.7 With multiple complications	0.696	0.304
E11.0 With coma	0.696	0.304
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.695	0.305
Y83.1 Surgical operation with implant of artificial internal device	0.695	0.305
Q60-Q64 Congenital malformations of the urinary system	0.695	0.305
E35 Disorders of endocrine glands in diseases classified elsewhere	0.694	0.306
E34 Other endocrine disorders	0.694	0.306
E32 Diseases of thymus	0.694	0.306
E31 Polyglandular dysfunction	0.694	0.306
E30 Disorders of puberty, not elsewhere classified	0.694	0.306
E26 Hyperaldosteronism	0.694	0.306
E25 Adrenogenital disorders	0.694	0.306
E24 Cushing's syndrome	0.694	0.306
E20 Hypoparathyroidism	0.694	0.306
N08.5 Glomerular disorders in systemic connective tissue disorders	0.692	0.308
V40-V49 Car occupant injured in transport accident	0.690	0.310
T68 Hypothermia	0.690	0.310
E55 Vitamin D deficiency	0.690	0.310
I35.2 Aortic (valve) stenosis with insufficiency	0.689	0.311
Q50-Q56 Congenital malformations of genital organs	0.688	0.312
E11.6 With other specified complications	0.687	0.313
N05 Unspecified nephritic syndrome	0.687	0.313
G62.8 Other specified polyneuropathies	0.686	0.313
Y52.1 Calcium-channel blockers	0.686	0.314
I22.8 Subsequent myocardial infarction of other sites	0.685	0.315
G62.2 Polyneuropathy due to other toxic agents	0.685	0.315
G62.1 Alcoholic polyneuropathy	0.685	0.315
Q80-Q89 Other congenital malformations	0.684	0.316
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.684	0.316
L02 Cutaneous abscess, furuncle and carbuncle	0.684	0.316
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.683	0.317
N25-N29 Other disorders of kidney and ureter	0.682	0.318
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.682	0.318
I38 Endocarditis, valve unspecified	0.682	0.318
E10.8 With unspecified complications	0.682	0.318
E10.7 With multiple complications	0.682	0.318
E10.6 With other specified complications	0.682	0.318
E10.0 With coma	0.682	0.318
S62.0 Fracture of navicular [scaphoid] bone of hand	0.681	0.319
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.680	0.320
Q35-Q37 Cleft lip and cleft palate	0.680	0.320
Q30-Q34 Congenital malformations of the respiratory system	0.680	0.320
Q00-Q07 Congenital malformations of the nervous system	0.680	0.320
I73.1 Thromboangiitis obliterans [Buerger]	0.680	0.320
J34.8 Other specified disorders of nose and nasal sinuses	0.679	0.321
N07 Hereditary nephropathy, not elsewhere classified	0.679	0.321
N06 Isolated proteinuria with specified morphological lesion	0.679	0.321
N01 Rapidly progressive nephritic syndrome	0.679	0.321
N00 Acute nephritic syndrome	0.679	0.321
G83.4 Cauda equina syndrome	0.679	0.321
T79-T79 Certain early complications of trauma	0.678	0.322
W20-W49 Exposure to inanimate mechanical forces	0.677	0.323
I95-I99 Other and unspecified disorders of the circulatory system	0.677	0.323
N61 Inflammatory disorders of breast	0.676	0.324
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.676	0.324
N03 Chronic nephritic syndrome	0.676	0.324
V80-V89 Other land transport accidents	0.675	0.325
Q25 Congenital malformations of great arteries	0.674	0.326
Q28 Other congenital malformations of circulatory system	0.674	0.326
J47 Bronchiectasis	0.674	0.326
I50.0 Congestive heart failure	0.673	0.327
I67.8 Other specified cerebrovascular diseases	0.673	0.327
S60.2 Contusion of other parts of wrist and hand	0.672	0.328
Y45.0 Opioids and related analgesics	0.671	0.329
J43.2 Centrilobular emphysema	0.670	0.330
Q23 Congenital malformations of aortic and mitral valves	0.670	0.330
G83.9 Paralytic syndrome, unspecified	0.670	0.330
I71 Aortic aneurysm and dissection	0.669	0.331
S70-S79 Injuries to the hip and thigh	0.668	0.332
I44.3 Other and unspecified atrioventricular block	0.668	0.332
U89 Agent resistant to other and unspecified antibiotics	0.667	0.333
E65-E68 Obesity and other hyperalimentation	0.667	0.333
Y35-Y36 Legal intervention and operations of war	0.666	0.333
Y10-Y34 Event of undetermined intent	0.666	0.333
X85-X99 Assault	0.666	0.333
X58-X59 Accidental exposure to other and unspecified factors	0.666	0.333
X30-X39 Exposure to forces of nature	0.666	0.333
X20-X29 Contact with venomous animals and plants	0.666	0.333
X10-X19 Contact with heat and hot substances	0.666	0.333
X00-X09 Exposure to smoke, fire and flames	0.666	0.333
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.666	0.333
W75-W84 Other accidental threats to breathing	0.666	0.333
W65-W74 Accidental drowning and submersion	0.666	0.333
V98-V99 Other and unspecified transport accidents	0.666	0.333
V95-V97 Air and space transport accidents	0.666	0.333
V90-V94 Water transport accidents	0.666	0.333
V70-V79 Bus occupant injured in transport accident	0.666	0.333
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.666	0.333
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.666	0.333
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.666	0.333
V01-V09 Pedestrian injured in transport accident	0.666	0.333
D68.8 Other specified coagulation defects	0.665	0.335
I30 Acute pericarditis	0.665	0.335
J39 Other diseases of upper respiratory tract	0.664	0.336
I37.1 Pulmonary valve insufficiency	0.664	0.336
M45 Ankylosing spondylitis	0.662	0.338
J99 Respiratory disorders in diseases classified elsewhere	0.662	0.338
S08 Traumatic amputation of part of head	0.661	0.338
S07 Crushing injury of head	0.661	0.338
S04 Injury of cranial nerves	0.661	0.338
S03 Dislocation, sprain and strain of joints and ligaments of head	0.661	0.338
S60.9 Superficial injury of wrist and hand, unspecified	0.661	0.339
V20-V29 Motorcycle rider injured in transport accident	0.660	0.340
I42.2 Other hypertrophic cardiomyopathy	0.660	0.340
X50-X57 Overexertion, travel and privation	0.660	0.340
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.660	0.340
L05 Pilonidal cyst	0.660	0.340
M65-M68 Disorders of synovium and tendon	0.660	0.340
Q21 Congenital malformations of cardiac septa	0.658	0.341
G60.0 Hereditary motor and sensory neuropathy	0.658	0.342
I27.2 Other secondary pulmonary hypertension	0.658	0.342
S62.4 Multiple fractures of metacarpal bones	0.658	0.342
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.656	0.344
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.655	0.345
S00.1 Contusion of eyelid and periocular area	0.654	0.346
G83.1 Monoplegia of lower limb	0.654	0.346
N04 Nephrotic syndrome	0.653	0.346
N08.8 Glomerular disorders in other diseases classified elsewhere	0.653	0.347
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.653	0.347
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.653	0.347
N08.1 Glomerular disorders in neoplastic diseases	0.653	0.347
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.653	0.347
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.653	0.347
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.653	0.347
S68.8 Traumatic amputation of other parts of wrist and hand	0.653	0.347
S68.4 Traumatic amputation of hand at wrist level	0.653	0.347
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.653	0.347
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.653	0.347
S68.0 Traumatic amputation of thumb (complete)(partial)	0.653	0.347
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.653	0.347
G82 Paraplegia and tetraplegia	0.652	0.348
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.652	0.348
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.652	0.348
Y49 Psychotropic drugs, not elsewhere classified	0.652	0.348
Y41 Other systemic anti-infectives and antiparasitics	0.652	0.348
N19 Unspecified renal failure	0.651	0.349
G20-G26 Extrapyramidal and movement disorders	0.651	0.349
I05 Rheumatic mitral valve diseases	0.648	0.352
T17 Foreign body in respiratory tract	0.647	0.352
S00.9 Superficial injury of head, part unspecified	0.647	0.353
E28.2 Polycystic ovarian syndrome	0.647	0.353
Y48 Anaesthetics and therapeutic gases	0.646	0.354
T23 Burn and corrosion of wrist and hand	0.646	0.354
T78 Adverse effects, not elsewhere classified	0.646	0.354
S00.7 Multiple superficial injuries of head	0.645	0.355
S00.4 Superficial injury of ear	0.645	0.355
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.645	0.355
G63.2 Diabetic polyneuropathy	0.645	0.355
M15 Polyarthrosis	0.645	0.355
M00-M03 Infectious arthropathies	0.644	0.355
I72.3 Aneurysm of iliac artery	0.644	0.355
E10.1 With ketoacidosis	0.644	0.356
Y51 Drugs primarily affecting the autonomic nervous system	0.644	0.356
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.644	0.356
J69 Pneumonitis due to solids and liquids	0.643	0.356
E13.9 Without complications	0.643	0.357
U81 Agent resistant to vancomycin and related antibiotics	0.642	0.358
U50 Level of care administered to neonates	0.642	0.358
U07 Emergency use of U07	0.642	0.358
U06 Emergency use of U06	0.642	0.358
U04 Severe acute respiratory syndrome [SARS]	0.642	0.358
U52 First in a series of a regular day/night admissions	0.642	0.358
S62.60 Fracture of other finger (closed)	0.642	0.358
E27 Other disorders of adrenal gland	0.642	0.358
J43.8 Other emphysema	0.642	0.358
J43.1 Panlobular emphysema	0.642	0.358
J43.0 MacLeod's syndrome	0.642	0.358
G70 Myasthenia gravis and other myoneural disorders	0.641	0.359
I67.0 Dissection of cerebral arteries, nonruptured	0.641	0.359
D69 Purpura and other haemorrhagic conditions	0.641	0.359
M19.8 Other specified arthrosis	0.640	0.360
S62.8 Fracture of other and unspecified parts of wrist and hand	0.640	0.360
I60 Subarachnoid haemorrhage	0.640	0.360
S62.1 Fracture of other carpal bone(s)	0.640	0.360
T87 Complications peculiar to reattachment and amputation	0.639	0.361
Y83.5 Amputation of limb(s)	0.639	0.361
E10.3 With ophthalmic complications	0.638	0.362
Chapter I Certain infectious and parasitic diseases	0.638	0.362
J98 Other respiratory disorders	0.638	0.362
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.637	0.363
M19.00 Primary arthrosis of other joints (Multiple sites)	0.637	0.363
I09 Other rheumatic heart diseases	0.637	0.363
I06 Rheumatic aortic valve diseases	0.637	0.363
N17.8 Other acute renal failure	0.636	0.364
N17.2 Acute renal failure with medullary necrosis	0.636	0.364
N17.1 Acute renal failure with acute cortical necrosis	0.636	0.364
N17.0 Acute renal failure with tubular necrosis	0.636	0.364
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.634	0.366
S01.2 Open wound of nose	0.634	0.366
M19.01 Primary arthrosis of other joints (Shoulder region)	0.634	0.366
S30 Superficial injury of abdomen, lower back and pelvis	0.632	0.367
I51.3 Intracardiac thrombosis, not elsewhere classified	0.632	0.368
Q18 Other congenital malformations of face and neck	0.632	0.368
Chapter XV Pregnancy, childbirth and the puerperium	0.631	0.369
M18 Arthrosis of first carpometacarpal joint	0.630	0.370
S69 Other and unspecified injuries of wrist and hand	0.629	0.370
I51.8 Other ill-defined heart diseases	0.629	0.371
I51.9 Heart disease, unspecified	0.629	0.371
J34.2 Deviated nasal septum	0.628	0.372
J96 Respiratory failure, not elsewhere classified	0.628	0.372
M48 Other spondylopathies	0.628	0.372
L40-L45 Papulosquamous disorders	0.628	0.372
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.627	0.373
U80.8 Agent resistant to other penicillin-related antibiotic	0.627	0.373
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.627	0.373
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.627	0.373
G61.8 Other inflammatory polyneuropathies	0.627	0.373
T18.1 Foreign body in oesophagus	0.626	0.374
I42.0 Dilated cardiomyopathy	0.626	0.374
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.626	0.374
M40-M43 Deforming dorsopathies	0.625	0.375
I61 Intracerebral haemorrhage	0.625	0.375
S62.5 Fracture of thumb	0.624	0.376
Y45.5 4-Aminophenol derivatives	0.624	0.376
D60-D64 Aplastic and other anaemias	0.623	0.377
Y59 Other and unspecified vaccines and biological substances	0.622	0.378
Y58 Bacterial vaccines	0.622	0.378
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.622	0.378
Y53 Agents primarily affecting the gastro-intestinal system	0.622	0.378
Y50 Central nervous system stimulants, not elsewhere classified	0.622	0.378
Y47 Sedatives, hypnotics and antianxiety drugs	0.622	0.378
Y46 Antiepileptics and anti-Parkinsonism drugs	0.622	0.378
J18.9 Pneumonia, unspecified	0.622	0.378
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.622	0.378
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.621	0.379
S64 Injury of nerves at wrist and hand level	0.621	0.379
S62.3 Fracture of other metacarpal bone	0.621	0.379
N60.1 Diffuse cystic mastopathy	0.620	0.379
J86 Pyothorax	0.620	0.380
I07 Rheumatic tricuspid valve diseases	0.620	0.380
I64 Stroke, not specified as haemorrhage or infarction	0.619	0.381
E23.0 Hypopituitarism	0.619	0.381
I15 Secondary hypertension	0.619	0.381
I13 Hypertensive heart and renal disease	0.619	0.381
I72.9 Aneurysm of unspecified site	0.619	0.381
I72.6 Aneurysm and dissection of vertebral artery	0.619	0.381
I72.5 Aneurysm and dissection of other precerebral arteries	0.619	0.381
I72.2 Aneurysm of renal artery	0.619	0.381
I72.1 Aneurysm of artery of upper extremity	0.619	0.381
J18.1 Lobar pneumonia, unspecified	0.618	0.382
E21.5 Disorder of parathyroid gland, unspecified	0.617	0.383
E21.4 Other specified disorders of parathyroid gland	0.617	0.383
E21.2 Other hyperparathyroidism	0.617	0.383
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.617	0.383
N60.3 Fibrosclerosis of breast	0.617	0.383
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.617	0.383
M14 Arthropathies in other diseases classified elsewhere	0.616	0.384
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.616	0.384
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.615	0.385
M19.02 Primary arthrosis of other joints (Upper arm)	0.614	0.386
E55.9 Vitamin D deficiency, unspecified	0.613	0.387

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations