TreeWAS – Variant ID: rs57740770

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10.9 Without complications	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001	0.000
E10.3 With ophthalmic complications	0.996	0.004	0.000
Chapter XI Diseases of the digestive system	0.994	0.006	0.000
K90-K93 Other diseases of the digestive system	0.983	0.017	0.000
K90 Intestinal malabsorption	0.977	0.023	0.000
K90.0 Coeliac disease	0.973	0.027	0.000
Chapter VII Diseases of the eye and adnexa	0.965	0.035	0.000
H30-H36 Disorders of choroid and retina	0.956	0.044	0.000
H36 Retinal disorders in diseases classified elsewhere	0.951	0.049	0.000
H36.0 Diabetic retinopathy	0.947	0.053	0.000
E10.4 With neurological complications	0.940	0.060	0.000
S40-S49 Injuries to the shoulder and upper arm	0.936	0.064	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.929	0.071	0.000
S50-S59 Injuries to the elbow and forearm	0.928	0.072	0.000
E10.1 With ketoacidosis	0.920	0.080	0.000
K55-K64 Other diseases of intestines	0.913	0.087	0.000
K62.1 Rectal polyp	0.909	0.091	0.000
K62 Other diseases of anus and rectum	0.905	0.095	0.000
Chapter VI Diseases of the nervous system	0.901	0.099	0.000
K40-K46 Hernia	0.899	0.101	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.898	0.102	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.886	0.114	0.000
S42 Fracture of shoulder and upper arm	0.881	0.119	0.000
E14 Unspecified diabetes mellitus	0.877	0.123	0.000
K81 Cholecystitis	0.876	0.124	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.875	0.125	0.000
G35 Multiple sclerosis	0.872	0.128	0.000
S80-S89 Injuries to the knee and lower leg	0.870	0.130	0.000
S52 Fracture of forearm	0.868	0.132	0.000
Chapter II Neoplasms	0.867	0.133	0.000
T66-T78 Other and unspecified effects of external causes	0.867	0.133	0.000
S60-S69 Injuries to the wrist and hand	0.866	0.134	0.000
K70-K77 Diseases of liver	0.864	0.136	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.860	0.140	0.000
S20-S29 Injuries to the thorax	0.855	0.145	0.000
E65-E68 Obesity and other hyperalimentation	0.854	0.146	0.000
K83 Other diseases of biliary tract	0.852	0.148	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.849	0.151	0.000
E07 Other disorders of thyroid	0.848	0.152	0.000
K41 Femoral hernia	0.846	0.154	0.000
K55 Vascular disorders of intestine	0.841	0.159	0.000
Chapter V Mental and behavioural disorders	0.836	0.164	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.831	0.169	0.000
H34 Retinal vascular occlusions	0.831	0.169	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.829	0.171	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.822	0.178	0.000
K81.1 Chronic cholecystitis	0.821	0.179	0.000
K55.2 Angiodysplasia of colon	0.812	0.188	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.809	0.191	0.000
E10.5 With peripheral circulatory complications	0.808	0.192	0.000
Chapter I Certain infectious and parasitic diseases	0.806	0.193	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.804	0.196	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.803	0.197	0.000
E05.9 Thyrotoxicosis, unspecified	0.802	0.198	0.000
Chapter XX External causes of morbidity and mortality	0.799	0.201	0.000
E16 Other disorders of pancreatic internal secretion	0.785	0.215	0.000
K63 Other diseases of intestine	0.777	0.223	0.000
H43-H45 Disorders of vitreous body and globe	0.776	0.224	0.000
T78 Adverse effects, not elsewhere classified	0.772	0.228	0.000
K81.9 Cholecystitis, unspecified	0.770	0.230	0.000
K42 Umbilical hernia	0.770	0.230	0.000
S52.5 Fracture of lower end of radius	0.766	0.234	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.765	0.235	0.000
K83.1 Obstruction of bile duct	0.761	0.239	0.000
S82 Fracture of lower leg, including ankle	0.754	0.246	0.000
S42.0 Fracture of clavicle	0.753	0.247	0.000
E14.9 Without complications	0.751	0.249	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.750	0.250	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.750	0.250	0.000
E66 Obesity	0.750	0.250	0.000
S90-S99 Injuries to the ankle and foot	0.749	0.251	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.746	0.254	0.000
T81 Complications of procedures, not elsewhere classified	0.742	0.258	0.000
K70 Alcoholic liver disease	0.742	0.258	0.000
C50-C50 Malignant neoplasm of breast	0.740	0.260	0.000
E07.9 Disorder of thyroid, unspecified	0.740	0.260	0.000
Chapter XXII Codes for special purposes	0.739	0.261	0.000
K63.5 Polyp of colon	0.738	0.262	0.000
C43 Malignant melanoma of skin	0.737	0.263	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.737	0.263	0.000
E20-E35 Disorders of other endocrine glands	0.735	0.265	0.000
K35-K38 Diseases of appendix	0.730	0.270	0.000
G90-G99 Other disorders of the nervous system	0.728	0.272	0.000
K91.4 Colostomy and enterostomy malfunction	0.725	0.275	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.722	0.278	0.000
E16.2 Hypoglycaemia, unspecified	0.721	0.279	0.000
S52.6 Fracture of lower end of both ulna and radius	0.719	0.281	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.717	0.283	0.000
E10.8 With unspecified complications	0.717	0.283	0.000
E10.7 With multiple complications	0.717	0.283	0.000
E10.6 With other specified complications	0.717	0.283	0.000
E10.2 With renal complications	0.717	0.283	0.000
E10.0 With coma	0.717	0.283	0.000
E40-E46 Malnutrition	0.717	0.283	0.000
E13 Other specified diabetes mellitus	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283	0.000
E03.8 Other specified hypothyroidism	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
H40-H42 Glaucoma	0.717	0.283	0.000
K85 Acute pancreatitis	0.717	0.283	0.000
T33-T35 Frostbite	0.716	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.283	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.283	0.000
T00-T07 Injuries involving multiple body regions	0.716	0.283	0.000
S10-S19 Injuries to the neck	0.716	0.283	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.716	0.284	0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.716	0.284	0.000
S42.3 Fracture of shaft of humerus	0.716	0.284	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.715	0.285	0.000
E11 Non-insulin-dependent diabetes mellitus	0.714	0.286	0.000
H34.8 Other retinal vascular occlusions	0.713	0.286	0.000
S42.1 Fracture of scapula	0.713	0.287	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.712	0.288	0.000
K62.3 Rectal prolapse	0.710	0.289	0.000
S50 Superficial injury of forearm	0.708	0.292	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.707	0.293	0.000
W00-W19 Falls	0.706	0.294	0.000
T79-T79 Certain early complications of trauma	0.705	0.295	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.705	0.295	0.000
K86 Other diseases of pancreas	0.705	0.295	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.704	0.296	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.704	0.296	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.702	0.298	0.000
E14.3 With ophthalmic complications	0.702	0.298	0.000
K90.8 Other intestinal malabsorption	0.700	0.299	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.700	0.299	0.000
K90.3 Pancreatic steatorrhoea	0.700	0.299	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.700	0.299	0.000
K90.1 Tropical sprue	0.700	0.299	0.000
C15-C26 Malignant neoplasms of digestive organs	0.700	0.300	0.000
T78.4 Allergy, unspecified	0.700	0.300	0.000
S60 Superficial injury of wrist and hand	0.698	0.302	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.698	0.302	0.000
K83.0 Cholangitis	0.696	0.304	0.000
F30-F39 Mood [affective] disorders	0.696	0.304	0.000
T93 Sequelae of injuries of lower limb	0.694	0.306	0.000
S52.50 Fracture of lower end of radius (closed)	0.693	0.307	0.000
S64 Injury of nerves at wrist and hand level	0.692	0.308	0.000
G37 Other demyelinating diseases of central nervous system	0.691	0.309	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.691	0.309	0.000
S52.1 Fracture of upper end of radius	0.691	0.309	0.000
H10-H13 Disorders of conjunctiva	0.690	0.310	0.000
A00-A09 Intestinal infectious diseases	0.689	0.310	0.001
H32 Chorioretinal disorders in diseases classified elsewhere	0.686	0.314	0.000
H31 Other disorders of choroid	0.686	0.314	0.000
H30 Chorioretinal inflammation	0.686	0.314	0.000
E06 Thyroiditis	0.685	0.315	0.000
S42.2 Fracture of upper end of humerus	0.685	0.315	0.000
K90.9 Intestinal malabsorption, unspecified	0.684	0.316	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.682	0.318	0.000
E11.3 With ophthalmic complications	0.678	0.322	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.676	0.324	0.000
D50-D53 Nutritional anaemias	0.674	0.326	0.000
H55-H59 Other disorders of eye and adnexa	0.673	0.327	0.000
K72 Hepatic failure, not elsewhere classified	0.672	0.328	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.671	0.329	0.000
S48 Traumatic amputation of shoulder and upper arm	0.671	0.329	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.671	0.329	0.000
S44 Injury of nerves at shoulder and upper arm level	0.671	0.329	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.671	0.329	0.000
S41 Open wound of shoulder and upper arm	0.671	0.329	0.000
S40 Superficial injury of shoulder and upper arm	0.671	0.329	0.000
S47 Crushing injury of shoulder and upper arm	0.671	0.329	0.000
S81 Open wound of lower leg	0.670	0.330	0.000
E66.8 Other obesity	0.669	0.331	0.000
G30-G32 Other degenerative diseases of the nervous system	0.668	0.331	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.668	0.332	0.000
C43.4 Malignant melanoma of scalp and neck	0.667	0.333	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.666	0.334	0.000
S51 Open wound of forearm	0.666	0.334	0.000
S59 Other and unspecified injuries of forearm	0.666	0.334	0.000
S58 Traumatic amputation of forearm	0.666	0.334	0.000
S57 Crushing injury of forearm	0.666	0.334	0.000
S56 Injury of muscle and tendon at forearm level	0.666	0.334	0.000
S55 Injury of blood vessels at forearm level	0.666	0.334	0.000
S54 Injury of nerves at forearm level	0.666	0.334	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.666	0.334	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.666	0.334	0.000
S70-S79 Injuries to the hip and thigh	0.665	0.334	0.000
K62.7 Radiation proctitis	0.665	0.335	0.000
K75 Other inflammatory liver diseases	0.665	0.335	0.000
D60-D64 Aplastic and other anaemias	0.663	0.337	0.000
S42.00 Fracture of clavicle (closed)	0.662	0.338	0.000
S42.4 Fracture of lower end of humerus	0.661	0.339	0.000
S62 Fracture at wrist and hand level	0.660	0.339	0.000
K62.0 Anal polyp	0.659	0.341	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.658	0.342	0.000
E50-E64 Other nutritional deficiencies	0.657	0.342	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.655	0.345	0.000
K64 Haemorrhoids and perianal venous thrombosis	0.655	0.345	0.000
C44 Other malignant neoplasms of skin	0.651	0.349	0.000
Q80-Q89 Other congenital malformations	0.650	0.350	0.000
H34.2 Other retinal artery occlusions	0.649	0.351	0.000
K62.4 Stenosis of anus and rectum	0.649	0.351	0.000
K62.2 Anal prolapse	0.649	0.351	0.000
C50 Malignant neoplasm of breast	0.649	0.351	0.000
S20 Superficial injury of thorax	0.648	0.352	0.000
F41 Other anxiety disorders	0.647	0.353	0.000
G70-G73 Diseases of myoneural junction and muscle	0.646	0.354	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.646	0.354	0.000
K45 Other abdominal hernia	0.644	0.356	0.000
E05.8 Other thyrotoxicosis	0.644	0.356	0.000
E05.5 Thyroid crisis or storm	0.644	0.356	0.000
E05.4 Thyrotoxicosis factitia	0.644	0.356	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.644	0.356	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.644	0.356	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.644	0.356	0.000
H43 Disorders of vitreous body	0.644	0.356	0.000
S27 Injury of other and unspecified intrathoracic organs	0.641	0.359	0.000
S82.8 Fractures of other parts of lower leg	0.639	0.361	0.000
K43 Ventral hernia	0.636	0.364	0.000
G36 Other acute disseminated demyelination	0.635	0.365	0.000
A30-A49 Other bacterial diseases	0.634	0.365	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.633	0.367	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.631	0.368	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.631	0.368	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.631	0.368	0.000
Q60-Q64 Congenital malformations of the urinary system	0.629	0.371	0.000
S52.0 Fracture of upper end of ulna	0.629	0.371	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.629	0.371	0.000
E14.8 With unspecified complications	0.628	0.371	0.000
E14.7 With multiple complications	0.628	0.371	0.000
E14.6 With other specified complications	0.628	0.371	0.000
E14.5 With peripheral circulatory complications	0.628	0.371	0.000
E14.4 With neurological complications	0.628	0.371	0.000
E14.2 Withrenal complications	0.628	0.371	0.000
E14.1 With ketoacidosis	0.628	0.371	0.000
E14.0 With coma	0.628	0.371	0.000
K81.8 Other cholecystitis	0.628	0.372	0.000
K70.4 Alcoholic hepatic failure	0.628	0.372	0.000
E15 Nondiabetic hypoglycaemic coma	0.627	0.373	0.000
K91.3 Postoperative intestinal obstruction	0.626	0.374	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.626	0.374	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.624	0.376	0.000
K83.8 Other specified diseases of biliary tract	0.624	0.376	0.000
K63.2 Fistula of intestine	0.624	0.376	0.000
S89 Other and unspecified injuries of lower leg	0.623	0.376	0.000
S88 Traumatic amputation of lower leg	0.623	0.376	0.000
S87 Crushing injury of lower leg	0.623	0.376	0.000
S86 Injury of muscle and tendon at lower leg level	0.623	0.376	0.000
S85 Injury of blood vessels at lower leg level	0.623	0.376	0.000
S84 Injury of nerves at lower leg level	0.623	0.376	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.623	0.377	0.000
K42.9 Umbilical hernia without obstruction or gangrene	0.623	0.377	0.000
S52.9 Fracture of forearm, part unspecified	0.622	0.378	0.000
S52.8 Fracture of other parts of forearm	0.622	0.378	0.000
S52.7 Multiple fractures of forearm	0.622	0.378	0.000
S52.4 Fracture of shafts of both ulna and radius	0.622	0.378	0.000
S52.3 Fracture of shaft of radius	0.622	0.378	0.000
S52.2 Fracture of shaft of ulna	0.622	0.378	0.000
K74 Fibrosis and cirrhosis of liver	0.622	0.378	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.622	0.378	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.622	0.378	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.622	0.378	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.622	0.378	0.000
X20-X29 Contact with venomous animals and plants	0.622	0.378	0.000
T75 Effects of other external causes	0.622	0.378	0.000
T74 Maltreatment syndromes	0.622	0.378	0.000
T73 Effects of other deprivation	0.622	0.378	0.000
T70 Effects of air pressure and water pressure	0.622	0.378	0.000
T69 Other effects of reduced temperature	0.622	0.378	0.000
T67 Effects of heat and light	0.622	0.378	0.000
T71 Asphyxiation	0.622	0.378	0.000
T68 Hypothermia	0.622	0.378	0.000
T66 Unspecified effects of radiation	0.622	0.378	0.000
S69 Other and unspecified injuries of wrist and hand	0.621	0.379	0.000
S67 Crushing injury of wrist and hand	0.621	0.379	0.000
S65 Injury of blood vessels at wrist and hand level	0.621	0.379	0.000
K77 Liver disorders in diseases classified elsewhere	0.620	0.380	0.000
K73 Chronic hepatitis, not elsewhere classified	0.620	0.380	0.000
K71 Toxic liver disease	0.620	0.380	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.619	0.381	0.000
K62.9 Disease of anus and rectum, unspecified	0.619	0.381	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.619	0.381	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.618	0.382	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.616	0.383	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.616	0.383	0.000
Q50-Q56 Congenital malformations of genital organs	0.616	0.383	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.616	0.383	0.000
Q35-Q37 Cleft lip and cleft palate	0.616	0.383	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.616	0.383	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.616	0.383	0.000
Q00-Q07 Congenital malformations of the nervous system	0.616	0.383	0.000
H35 Other retinal disorders	0.616	0.384	0.000
V40-V49 Car occupant injured in transport accident	0.615	0.385	0.000
A04 Other bacterial intestinal infections	0.615	0.385	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.615	0.385	0.000
S29 Other and unspecified injuries of thorax	0.613	0.387	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.613	0.387	0.000
S26 Injury of heart	0.613	0.387	0.000
S25 Injury of blood vessels of thorax	0.613	0.387	0.000
S24 Injury of nerves and spinal cord at thorax level	0.613	0.387	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.613	0.387	0.000
S21 Open wound of thorax	0.613	0.387	0.000
E67 Other hyperalimentation	0.612	0.387	0.000
E68 Sequelae of hyperalimentation	0.612	0.387	0.000
E65 Localised adiposity	0.612	0.387	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.613	0.387	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.612	0.388	0.000
S82.3 Fracture of lower end of tibia	0.611	0.389	0.000
K83.9 Disease of biliary tract, unspecified	0.611	0.389	0.000
K83.5 Biliary cyst	0.611	0.389	0.000
K83.4 Spasm of sphincter of Oddi	0.611	0.389	0.000
K83.3 Fistula of bile duct	0.611	0.389	0.000
K83.2 Perforation of bile duct	0.611	0.389	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.610	0.390	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.609	0.390	0.000
S32 Fracture of lumbar spine and pelvis	0.609	0.390	0.000
T90 Sequelae of injuries of head	0.609	0.391	0.000
T87 Complications peculiar to reattachment and amputation	0.609	0.391	0.000
T86 Failure and rejection of transplanted organs and tissues	0.609	0.391	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.609	0.391	0.000
K37 Unspecified appendicitis	0.609	0.391	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.609	0.391	0.000
K46 Unspecified abdominal hernia	0.609	0.391	0.000
B25-B34 Other viral diseases	0.608	0.392	0.000
E07.8 Other specified disorders of thyroid	0.608	0.392	0.000
E07.1 Dyshormogenetic goitre	0.608	0.392	0.000
E07.0 Hypersecretion of calcitonin	0.608	0.392	0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.607	0.393	0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.607	0.393	0.000
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.607	0.393	0.000
K41.1 Bilateral femoral hernia, with gangrene	0.607	0.393	0.000
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.607	0.393	0.000
F60-F69 Disorders of adult personality and behaviour	0.606	0.394	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.604	0.395	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.604	0.396	0.000
K86.3 Pseudocyst of pancreas	0.604	0.396	0.000
B35-B49 Mycoses	0.603	0.397	0.000
K55.8 Other vascular disorders of intestine	0.603	0.397	0.000
K55.1 Chronic vascular disorders of intestine	0.603	0.397	0.000
F80-F89 Disorders of psychological development	0.602	0.398	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.601	0.399	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.600	0.400	0.000
D00-D09 In situ neoplasms	0.600	0.400	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.599	0.401	0.000
F70-F79 Mental retardation	0.599	0.401	0.000
G91 Hydrocephalus	0.599	0.401	0.000
S42.30 Fracture of shaft of humerus (closed)	0.598	0.402	0.000
C64-C68 Malignant neoplasms of urinary tract	0.597	0.403	0.000
D80-D89 Certain disorders involving the immune mechanism	0.596	0.404	0.000
D55-D59 Haemolytic anaemias	0.596	0.404	0.000
H34.9 Retinal vascular occlusion, unspecified	0.595	0.404	0.000
H34.1 Central retinal artery occlusion	0.595	0.404	0.000
H34.0 Transient retinal artery occlusion	0.595	0.404	0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.596	0.404	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.595	0.405	0.000
K91.5 Postcholecystectomy syndrome	0.595	0.405	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.595	0.405	0.000
K91.1 Postgastric surgery syndromes	0.595	0.405	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.595	0.405	0.000
S42.10 Fracture of scapula (closed)	0.593	0.407	0.000
F33 Recurrent depressive disorder	0.592	0.408	0.000
W20-W49 Exposure to inanimate mechanical forces	0.592	0.408	0.000
Q27 Other congenital malformations of peripheral vascular system	0.591	0.409	0.000
H46 Optic neuritis	0.590	0.410	0.000
T98 Sequelae of other and unspecified effects of external causes	0.589	0.411	0.000
T95 Sequelae of burns, corrosions and frostbite	0.589	0.411	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.589	0.411	0.000
T91 Sequelae of injuries of neck and trunk	0.589	0.411	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.589	0.411	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.589	0.411	0.000
W10 Fall on and from stairs and steps	0.589	0.411	0.000
D68 Other coagulation defects	0.588	0.412	0.000
H25-H28 Disorders of lens	0.588	0.412	0.000
S82.2 Fracture of shaft of tibia	0.587	0.413	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.586	0.414	0.000
S61 Open wound of wrist and hand	0.586	0.414	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.584	0.416	0.000
D10-D36 Benign neoplasms	0.583	0.417	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.583	0.417	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.581	0.419	0.000
F99-F99 Unspecified mental disorder	0.581	0.419	0.000
Q28 Other congenital malformations of circulatory system	0.580	0.419	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.579	0.421	0.000
B99-B99 Other infectious diseases	0.578	0.422	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.578	0.422	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.578	0.422	0.000
B65-B83 Helminthiases	0.578	0.422	0.000
B50-B64 Protozoal diseases	0.578	0.422	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.578	0.422	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.578	0.422	0.000
A80-A89 Viral infections of the central nervous system	0.578	0.422	0.000
A75-A79 Rickettsioses	0.578	0.422	0.000
A70-A74 Other diseases caused by chlamydiae	0.578	0.422	0.000
A65-A69 Other spirochaetal diseases	0.578	0.422	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.578	0.422	0.000
A20-A28 Certain zoonotic bacterial diseases	0.578	0.422	0.000
A15-A19 Tuberculosis	0.578	0.422	0.000
F31 Bipolar affective disorder	0.577	0.423	0.000
Q21 Congenital malformations of cardiac septa	0.577	0.423	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.576	0.424	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.576	0.424	0.000
S37 Injury of urinary and pelvic organs	0.576	0.424	0.000
S36 Injury of intra-abdominal organs	0.576	0.424	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.576	0.424	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.576	0.424	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.576	0.424	0.000
S31 Open wound of abdomen, lower back and pelvis	0.576	0.424	0.000
V20-V29 Motorcycle rider injured in transport accident	0.575	0.425	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.575	0.425	0.000
K70.3 Alcoholic cirrhosis of liver	0.575	0.425	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.575	0.425	0.000
Y35-Y36 Legal intervention and operations of war	0.573	0.427	0.000
Y10-Y34 Event of undetermined intent	0.573	0.427	0.000
Y00-Y09 Assault	0.573	0.427	0.000
X85-X99 Assault	0.573	0.427	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.573	0.427	0.000
X50-X57 Overexertion, travel and privation	0.573	0.427	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.573	0.427	0.000
X30-X39 Exposure to forces of nature	0.573	0.427	0.000
X10-X19 Contact with heat and hot substances	0.573	0.427	0.000
X00-X09 Exposure to smoke, fire and flames	0.573	0.427	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.573	0.427	0.000
W75-W84 Other accidental threats to breathing	0.573	0.427	0.000
W65-W74 Accidental drowning and submersion	0.573	0.427	0.000
W50-W64 Exposure to animate mechanical forces	0.573	0.427	0.000
V98-V99 Other and unspecified transport accidents	0.573	0.427	0.000
V95-V97 Air and space transport accidents	0.573	0.427	0.000
V90-V94 Water transport accidents	0.573	0.427	0.000
V80-V89 Other land transport accidents	0.573	0.427	0.000
V70-V79 Bus occupant injured in transport accident	0.573	0.427	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.573	0.427	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.573	0.427	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.573	0.427	0.000
V01-V09 Pedestrian injured in transport accident	0.573	0.427	0.000
C51-C58 Malignant neoplasms of female genital organs	0.573	0.427	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.573	0.427	0.000
S80 Superficial injury of lower leg	0.573	0.427	0.000
A08 Viral and other specified intestinal infections	0.572	0.427	0.000
S22.0 Fracture of thoracic vertebra	0.572	0.428	0.000
T31 Burns classified according to extent of body surface involved	0.572	0.428	0.000
T14 Injury of unspecified body region	0.571	0.429	0.000
S92 Fracture of foot, except ankle	0.571	0.429	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.571	0.429	0.000
K76 Other diseases of liver	0.571	0.429	0.000
K82 Other diseases of gallbladder	0.569	0.431	0.000
T78.2 Anaphylactic shock, unspecified	0.568	0.432	0.000
T92 Sequelae of injuries of upper limb	0.568	0.432	0.000
S64.4 Injury of digital nerve of other finger	0.568	0.432	0.000
T81.8 Other complications of procedures, not elsewhere classified	0.566	0.434	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.565	0.435	0.000
F41.1 Generalised anxiety disorder	0.565	0.435	0.000
D12.5 Sigmoid colon	0.565	0.435	0.000
S52.10 Fracture of upper end of radius (closed)	0.564	0.436	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.563	0.437	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.563	0.437	0.000
E16.4 Abnormal secretion of gastrin	0.563	0.437	0.000
E16.3 Increased secretion of glucagon	0.563	0.437	0.000
E16.1 Other hypoglycaemia	0.563	0.437	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.563	0.437	0.000
C44.1 Skin of eyelid, including canthus	0.562	0.437	0.000
S22.1 Multiple fractures of thoracic spine	0.562	0.438	0.000
C43.5 Malignant melanoma of trunk	0.561	0.439	0.000
K85.9 Acute pancreatitis, unspecified	0.561	0.439	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.559	0.441	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.558	0.441	0.000
E28 Ovarian dysfunction	0.558	0.442	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.558	0.442	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.557	0.443	0.000
K63.4 Enteroptosis	0.557	0.443	0.000
K63.0 Abscess of intestine	0.557	0.443	0.000
X60-X84 Intentional self-harm	0.557	0.443	0.000
B15-B19 Viral hepatitis	0.556	0.443	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.556	0.444	0.000
K65-K67 Diseases of peritoneum	0.556	0.444	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.556	0.444	0.000
T78.9 Adverse effect, unspecified	0.554	0.446	0.000
T78.8 Other adverse effects, not elsewhere classified	0.554	0.446	0.000
T78.3 Angioneurotic oedema	0.554	0.446	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.554	0.446	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.554	0.446	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.553	0.447	0.000
E66.9 Obesity, unspecified	0.553	0.447	0.000
C44.7 Skin of lower limb, including hip	0.553	0.447	0.000
C50.1 Central portion of breast	0.553	0.447	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.553	0.447	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.552	0.448	0.000
K42.1 Umbilical hernia with gangrene	0.552	0.448	0.000
S60.8 Other superficial injuries of wrist and hand	0.551	0.449	0.000
S50.9 Superficial injury of forearm, unspecified	0.550	0.450	0.000
H44 Disorders of globe	0.550	0.450	0.000
C50.3 Lower-inner quadrant of breast	0.550	0.450	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations