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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs62262682
log Bayes Factor = 6.14122
Chromosome 3   position 49,722,761  (GRCh37) Explore rs62262682 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I20 Angina pectoris
1.000 0.000 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.999 0.001 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.999 0.001 0.000
I26 Pulmonary embolism
0.999 0.001 0.000
H40 Glaucoma
0.997 0.003 0.000
H40.0 Glaucoma suspect
0.996 0.004 0.000
I25 Chronic ischaemic heart disease
0.995 0.005 0.000
I20.9 Angina pectoris, unspecified
0.994 0.006 0.000
# Top node
0.994 0.006 0.000
H40-H42 Glaucoma
0.994 0.006 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.992 0.008 0.000
Chapter VII Diseases of the eye and adnexa
0.992 0.008 0.000
E10-E14 Diabetes mellitus
0.987 0.013 0.000
I25.2 Old myocardial infarction
0.982 0.018 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.977 0.023 0.000
I25.1 Atherosclerotic heart disease
0.973 0.027 0.000
E20-E35 Disorders of other endocrine glands
0.969 0.031 0.000
I21 Acute myocardial infarction
0.969 0.031 0.000
I20.8 Other forms of angina pectoris
0.967 0.033 0.000
I95 Hypotension
0.966 0.034 0.000
Chapter XX External causes of morbidity and mortality
0.963 0.037 0.000
E10 Insulin-dependent diabetes mellitus
0.955 0.045 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.952 0.048 0.000
E14 Unspecified diabetes mellitus
0.949 0.051 0.000
H40.8 Other glaucoma
0.940 0.060 0.000
Chapter VI Diseases of the nervous system
0.935 0.065 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.934 0.066 0.000
H40.9 Glaucoma, unspecified
0.933 0.067 0.000
G90-G99 Other disorders of the nervous system
0.924 0.076 0.000
E14.9 Without complications
0.919 0.081 0.000
Y43 Primarily systemic agents
0.907 0.093 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.903 0.097 0.000
E27 Other disorders of adrenal gland
0.891 0.109 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.888 0.112 0.000
I95.1 Orthostatic hypotension
0.886 0.114 0.000
I95.2 Hypotension due to drugs
0.880 0.120 0.000
I95.9 Hypotension, unspecified
0.880 0.120 0.000
Y43.3 Other antineoplastic drugs
0.871 0.129 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.870 0.130 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.863 0.137 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.858 0.142 0.000
E65-E68 Obesity and other hyperalimentation
0.853 0.147 0.000
I25.5 Ischaemic cardiomyopathy
0.848 0.152 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.843 0.157 0.000
E11 Non-insulin-dependent diabetes mellitus
0.842 0.158 0.000
Y52 Agents primarily affecting the cardiovascular system
0.839 0.161 0.000
M05-M14 Inflammatory polyarthropathies
0.833 0.161 0.006
G90 Disorders of autonomic nervous system
0.836 0.164 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.836 0.164 0.000
I20.1 Angina pectoris with documented spasm
0.826 0.174 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.820 0.180 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.817 0.183 0.000
Chapter I Certain infectious and parasitic diseases
0.816 0.184 0.000
G56 Mononeuropathies of upper limb
0.815 0.185 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.815 0.185 0.000
E10.2 With renal complications
0.810 0.190 0.000
M10 Gout
0.806 0.191 0.003
H40.5 Glaucoma secondary to other eye disorders
0.807 0.193 0.000
M13 Other arthritis
0.804 0.194 0.002
E22 Hyperfunction of pituitary gland
0.802 0.198 0.000
H10-H13 Disorders of conjunctiva
0.801 0.199 0.000
Q50-Q56 Congenital malformations of genital organs
0.800 0.200 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.799 0.201 0.000
E10.3 With ophthalmic complications
0.799 0.201 0.000
I20.0 Unstable angina
0.799 0.201 0.000
Y00-Y09 Assault
0.794 0.206 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.794 0.206 0.000
E27.8 Other specified disorders of adrenal gland
0.788 0.212 0.000
M10.9 Gout, unspecified
0.787 0.212 0.001
E14.6 With other specified complications
0.787 0.213 0.000
E10.4 With neurological complications
0.782 0.218 0.000
E28 Ovarian dysfunction
0.780 0.220 0.000
E10.0 With coma
0.780 0.220 0.000
M10.99 Gout, unspecified (Site unspecified)
0.772 0.228 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.772 0.228 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.769 0.231 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.768 0.232 0.000
M70-M79 Other soft tissue disorders
0.765 0.235 0.000
G56.0 Carpal tunnel syndrome
0.765 0.235 0.000
V40-V49 Car occupant injured in transport accident
0.764 0.236 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.764 0.236 0.000
H55-H59 Other disorders of eye and adnexa
0.759 0.241 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.757 0.243 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.757 0.243 0.000
M13.9 Arthritis, unspecified
0.757 0.243 0.000
Y44 Agents primarily affecting blood constituents
0.754 0.246 0.000
M11 Other crystal arthropathies
0.747 0.250 0.004
E66 Obesity
0.750 0.250 0.000
Y43.0 Antiallergic and antiemetic drugs
0.749 0.251 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.749 0.251 0.000
A30-A49 Other bacterial diseases
0.747 0.253 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.747 0.253 0.000
I60-I69 Cerebrovascular diseases
0.747 0.253 0.000
E10.8 With unspecified complications
0.746 0.254 0.000
E10.9 Without complications
0.745 0.255 0.000
H18 Other disorders of cornea
0.744 0.256 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.742 0.258 0.000
M40-M43 Deforming dorsopathies
0.740 0.260 0.000
W20-W49 Exposure to inanimate mechanical forces
0.740 0.260 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.739 0.261 0.000
E21.3 Hyperparathyroidism, unspecified
0.737 0.263 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.736 0.263 0.000
E10.5 With peripheral circulatory complications
0.735 0.265 0.000
E11.5 With peripheral circulatory complications
0.734 0.266 0.000
V10-V19 Pedal cyclist injured in transport accident
0.734 0.266 0.000
W75-W84 Other accidental threats to breathing
0.733 0.267 0.000
V98-V99 Other and unspecified transport accidents
0.733 0.267 0.000
M75 Shoulder lesions
0.731 0.269 0.000
E23 Hypofunction and other disorders of pituitary gland
0.730 0.270 0.000
V80-V89 Other land transport accidents
0.730 0.270 0.000
G93 Other disorders of brain
0.729 0.271 0.000
I95.0 Idiopathic hypotension
0.727 0.273 0.000
G57 Mononeuropathies of lower limb
0.726 0.274 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.725 0.275 0.000
G91 Hydrocephalus
0.722 0.278 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.721 0.279 0.000
G54 Nerve root and plexus disorders
0.719 0.281 0.000
Q80-Q89 Other congenital malformations
0.718 0.282 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.718 0.282 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I28 Other diseases of pulmonary vessels
0.716 0.284 0.000
H40.6 Glaucoma secondary to drugs
0.714 0.285 0.000
H40.4 Glaucoma secondary to eye inflammation
0.714 0.285 0.000
H40.3 Glaucoma secondary to eye trauma
0.714 0.285 0.000
I25.6 Silent myocardial ischaemia
0.714 0.286 0.000
I25.4 Coronary artery aneurysm
0.714 0.286 0.000
Y45.2 Propionic acid derivatives
0.713 0.287 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.713 0.287 0.000
H42 Glaucoma in diseases classified elsewhere
0.712 0.287 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.709 0.291 0.000
Y40 Systemic antibiotics
0.709 0.291 0.000
E12 Malnutrition-related diabetes mellitus
0.708 0.292 0.000
I22 Subsequent myocardial infarction
0.708 0.292 0.000
M13.0 Polyarthritis, unspecified
0.705 0.294 0.001
M75.2 Bicipital tendinitis
0.705 0.295 0.000
M86-M90 Other osteopathies
0.705 0.295 0.000
G95 Other diseases of spinal cord
0.704 0.296 0.000
M60-M63 Disorders of muscles
0.704 0.296 0.000
G51 Facial nerve disorders
0.702 0.298 0.000
E29 Testicular dysfunction
0.700 0.300 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.700 0.300 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.699 0.301 0.000
X10-X19 Contact with heat and hot substances
0.698 0.302 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.697 0.303 0.000
Q51 Congenital malformations of uterus and cervix
0.697 0.303 0.000
G50 Disorders of trigeminal nerve
0.696 0.304 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.695 0.305 0.000
E32 Diseases of thymus
0.695 0.305 0.000
E31 Polyglandular dysfunction
0.695 0.305 0.000
E30 Disorders of puberty, not elsewhere classified
0.695 0.305 0.000
E25 Adrenogenital disorders
0.695 0.305 0.000
E20 Hypoparathyroidism
0.695 0.305 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.694 0.306 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.694 0.306 0.000
E11.0 With coma
0.693 0.307 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.692 0.308 0.000
Y35-Y36 Legal intervention and operations of war
0.691 0.309 0.000
Y10-Y34 Event of undetermined intent
0.691 0.309 0.000
X85-X99 Assault
0.691 0.309 0.000
X30-X39 Exposure to forces of nature
0.691 0.309 0.000
X00-X09 Exposure to smoke, fire and flames
0.691 0.309 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.691 0.309 0.000
W65-W74 Accidental drowning and submersion
0.691 0.309 0.000
V95-V97 Air and space transport accidents
0.691 0.309 0.000
V90-V94 Water transport accidents
0.691 0.309 0.000
V70-V79 Bus occupant injured in transport accident
0.691 0.309 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.691 0.309 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.691 0.309 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.691 0.309 0.000
V01-V09 Pedestrian injured in transport accident
0.691 0.309 0.000
G52 Disorders of other cranial nerves
0.690 0.310 0.000
E26 Hyperaldosteronism
0.690 0.310 0.000
H47.1 Papilloedema, unspecified
0.688 0.312 0.000
W50-W64 Exposure to animate mechanical forces
0.688 0.312 0.000
M11.2 Other chondrocalcinosis
0.685 0.313 0.002
M13.98 Arthritis, unspecified (Other)
0.686 0.314 0.000
E34 Other endocrine disorders
0.686 0.314 0.000
E10.7 With multiple complications
0.685 0.315 0.000
E10.6 With other specified complications
0.685 0.315 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.684 0.316 0.000
Y59 Other and unspecified vaccines and biological substances
0.683 0.317 0.000
Y58 Bacterial vaccines
0.683 0.317 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.683 0.317 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.683 0.317 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.683 0.317 0.000
Y48 Anaesthetics and therapeutic gases
0.683 0.317 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.683 0.317 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.682 0.318 0.000
I10-I15 Hypertensive diseases
0.681 0.319 0.000
E27.9 Disorder of adrenal gland, unspecified
0.681 0.319 0.000
E14.8 With unspecified complications
0.681 0.319 0.000
E14.7 With multiple complications
0.681 0.319 0.000
E14.5 With peripheral circulatory complications
0.681 0.319 0.000
E14.4 With neurological complications
0.681 0.319 0.000
E14.2 Withrenal complications
0.681 0.319 0.000
E14.1 With ketoacidosis
0.681 0.319 0.000
E14.0 With coma
0.681 0.319 0.000
H21 Other disorders of iris and ciliary body
0.681 0.319 0.000
M91-M94 Chondropathies
0.679 0.321 0.000
H43-H45 Disorders of vitreous body and globe
0.678 0.322 0.000
E22.0 Acromegaly and pituitary gigantism
0.678 0.322 0.000
Y88 Sequelae of surgical and medical care as external cause
0.677 0.323 0.000
I95.8 Other hypotension
0.677 0.323 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.676 0.324 0.000
G57.8 Other mononeuropathies of lower limb
0.675 0.325 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.674 0.326 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.673 0.327 0.000
Y04 Assault by bodily force
0.672 0.328 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.672 0.328 0.000
H47.0 Disorders of optic nerve, not elsewhere classified
0.671 0.329 0.000
X60-X84 Intentional self-harm
0.669 0.331 0.000
E22.1 Hyperprolactinaemia
0.668 0.332 0.000
Y85 Sequelae of transport accidents
0.667 0.333 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.667 0.333 0.000
E66.9 Obesity, unspecified
0.667 0.333 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.663 0.337 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.663 0.337 0.000
G92 Toxic encephalopathy
0.662 0.337 0.000
M43 Other deforming dorsopathies
0.661 0.339 0.000
G94.1 Hydrocephalus in neoplastic disease
0.658 0.342 0.000
E00-E07 Disorders of thyroid gland
0.656 0.344 0.000
E24 Cushing's syndrome
0.654 0.346 0.000
G96 Other disorders of central nervous system
0.653 0.347 0.000
W22 Striking against or struck by other objects
0.651 0.348 0.000
Y43.9 Primarily systemic agent, unspecified
0.650 0.350 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.650 0.350 0.000
Y43.6 Enzymes, not elsewhere classified
0.650 0.350 0.000
Y43.5 Acidifying and alkalising agents
0.650 0.350 0.000
Y43.2 Antineoplastic natural products
0.650 0.350 0.000
E11.6 With other specified complications
0.649 0.351 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.648 0.352 0.000
Q35-Q37 Cleft lip and cleft palate
0.648 0.352 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.648 0.352 0.000
G70-G73 Diseases of myoneural junction and muscle
0.647 0.352 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.645 0.355 0.001
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.644 0.355 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.644 0.356 0.000
I21.9 Acute myocardial infarction, unspecified
0.644 0.356 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.643 0.356 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.643 0.357 0.000
Chapter VIII Diseases of the ear and mastoid process
0.642 0.358 0.000
X50-X57 Overexertion, travel and privation
0.642 0.358 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.641 0.359 0.001
H10 Conjunctivitis
0.641 0.359 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.640 0.360 0.000
E27.5 Adrenomedullary hyperfunction
0.639 0.361 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.639 0.361 0.000
E27.0 Other adrenocortical overactivity
0.639 0.361 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.639 0.361 0.000
G90.3 Multisystem degeneration
0.638 0.362 0.000
H55 Nystagmus and other irregular eye movements
0.638 0.362 0.000
A41 Other septicaemia
0.638 0.362 0.000
I99 Other and unspecified disorders of circulatory system
0.637 0.363 0.000
Q54 Hypospadias
0.637 0.363 0.000
Y52.1 Calcium-channel blockers
0.636 0.364 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.635 0.365 0.000
E28.2 Polycystic ovarian syndrome
0.634 0.366 0.000
E27.2 Addisonian crisis
0.632 0.368 0.000
E27.1 Primary adrenocortical insufficiency
0.631 0.369 0.000
H16 Keratitis
0.630 0.370 0.000
E11.8 With unspecified complications
0.629 0.370 0.000
Y45.5 4-Aminophenol derivatives
0.628 0.372 0.000
M75.3 Calcific tendinitis of shoulder
0.628 0.372 0.000
M13.09 Polyarthritis, unspecified (Site unspecified)
0.627 0.373 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.627 0.373 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.626 0.373 0.000
I67 Other cerebrovascular diseases
0.627 0.373 0.000
G30-G32 Other degenerative diseases of the nervous system
0.626 0.374 0.000
B25-B34 Other viral diseases
0.625 0.375 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.624 0.376 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.624 0.376 0.000
Y49.5 Other antipsychotics and neuroleptics
0.624 0.376 0.000
G90.2 Horner's syndrome
0.624 0.376 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.624 0.376 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.621 0.379 0.000
E65 Localised adiposity
0.621 0.379 0.000
G93.0 Cerebral cysts
0.621 0.379 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.620 0.379 0.000
H40.2 Primary angle-closure glaucoma
0.620 0.380 0.000
H18.1 Bullous keratopathy
0.620 0.380 0.000
X20-X29 Contact with venomous animals and plants
0.619 0.380 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.619 0.381 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.619 0.381 0.000
H17 Corneal scars and opacities
0.619 0.381 0.000
H15 Disorders of sclera
0.619 0.381 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.619 0.381 0.000
Q60-Q64 Congenital malformations of the urinary system
0.618 0.381 0.000
V20-V29 Motorcycle rider injured in transport accident
0.618 0.382 0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.617 0.383 0.000
E11.1 With ketoacidosis
0.617 0.383 0.000
Q00-Q07 Congenital malformations of the nervous system
0.617 0.383 0.000
Chapter V Mental and behavioural disorders
0.616 0.384 0.000
Q85 Phakomatoses, not elsewhere classified
0.616 0.384 0.000
I05-I09 Chronic rheumatic heart diseases
0.615 0.385 0.000
E40-E46 Malnutrition
0.614 0.386 0.000
G56.8 Other mononeuropathies of upper limb
0.613 0.387 0.000
I25.3 Aneurysm of heart
0.613 0.387 0.000
M89 Other disorders of bone
0.612 0.388 0.000
Y44.2 Anticoagulants
0.612 0.388 0.000
E67 Other hyperalimentation
0.612 0.388 0.000
E68 Sequelae of hyperalimentation
0.612 0.388 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.612 0.388 0.000
B50-B64 Protozoal diseases
0.610 0.389 0.000
G56.3 Lesion of radial nerve
0.610 0.390 0.000
B99-B99 Other infectious diseases
0.609 0.391 0.000
M75.4 Impingement syndrome of shoulder
0.609 0.391 0.000
I61 Intracerebral haemorrhage
0.608 0.392 0.000
Q53 Undescended testicle
0.608 0.392 0.000
H11 Other disorders of conjunctiva
0.606 0.394 0.000
E21.0 Primary hyperparathyroidism
0.606 0.394 0.000
Y45.8 Other analgesics and antipyretics
0.604 0.396 0.000
M62 Other disorders of muscle
0.604 0.396 0.000
Y43.4 Immunosuppressive agents
0.604 0.396 0.000
E11.7 With multiple complications
0.603 0.396 0.000
Y41.5 Antiviral drugs
0.603 0.397 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.603 0.397 0.000
Q51.3 Bicornate uterus
0.602 0.398 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.602 0.398 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.602 0.398 0.000
Y52.7 Peripheral vasodilators
0.602 0.398 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.602 0.398 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.602 0.398 0.000
B35-B49 Mycoses
0.602 0.398 0.000
M12 Other specific arthropathies
0.597 0.398 0.004
M09 Juvenile arthritis in diseases classified elsewhere
0.597 0.398 0.004
M08 Juvenile arthritis
0.597 0.398 0.004
A46 Erysipelas
0.601 0.399 0.000
E16 Other disorders of pancreatic internal secretion
0.600 0.400 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.600 0.400 0.000
M43.1 Spondylolisthesis
0.600 0.400 0.000
G90.8 Other disorders of autonomic nervous system
0.599 0.401 0.000
G90.4 Autonomic dysreflexia
0.599 0.401 0.000
G90.1 Familial dysautonomia [Riley-Day]
0.599 0.401 0.000
M13.94 Arthritis, unspecified (Hand)
0.599 0.401 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.599 0.401 0.000
E21.4 Other specified disorders of parathyroid gland
0.599 0.401 0.000
E21.2 Other hyperparathyroidism
0.599 0.401 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.599 0.401 0.000
Y79.2 Prosthetic and other implants, materials and accessory devices
0.598 0.402 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.597 0.403 0.000
H20 Iridocyclitis
0.596 0.404 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.594 0.406 0.000
Q43 Other congenital malformations of intestine
0.594 0.406 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.594 0.406 0.000
I10 Essential (primary) hypertension
0.593 0.407 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.591 0.409 0.000
G95.9 Disease of spinal cord, unspecified
0.591 0.409 0.000
G51.0 Bell's palsy
0.591 0.409 0.000
H46 Optic neuritis
0.590 0.410 0.000
M00-M03 Infectious arthropathies
0.589 0.411 0.000
E11.4 With neurological complications
0.588 0.412 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.588 0.412 0.000
I67.2 Cerebral atherosclerosis
0.588 0.412 0.000
W22.9 Unspecified place
0.588 0.412 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.588 0.412 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.588 0.412 0.000
Y43.1 Antineoplastic antimetabolites
0.586 0.414 0.000
Y89 Sequelae of other external causes
0.586 0.414 0.000
G12 Spinal muscular atrophy and related syndromes
0.586 0.414 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.585 0.415 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.585 0.415 0.000
A75-A79 Rickettsioses
0.585 0.415 0.000
A70-A74 Other diseases caused by chlamydiae
0.585 0.415 0.000
A65-A69 Other spirochaetal diseases
0.585 0.415 0.000
A20-A28 Certain zoonotic bacterial diseases
0.585 0.415 0.000
A15-A19 Tuberculosis
0.585 0.415 0.000
E10.1 With ketoacidosis
0.585 0.415 0.000
G56.4 Causalgia
0.584 0.415 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.584 0.416 0.000
Y45.4 Antirheumatics
0.584 0.416 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.584 0.416 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.583 0.417 0.000
M40 Kyphosis and lordosis
0.583 0.417 0.000
Y49.2 Other and unspecified antidepressants
0.582 0.418 0.000
M75.9 Shoulder lesion, unspecified
0.581 0.418 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.581 0.419 0.000
A49 Bacterial infection of unspecified site
0.581 0.419 0.000
M10.4 Other secondary gout
0.578 0.420 0.002
M10.3 Gout due to impairment of renal function
0.578 0.420 0.002
M10.2 Drug-induced gout
0.578 0.420 0.002
M10.1 Lead-induced gout
0.578 0.420 0.002
M10.0 Idiopathic gout
0.578 0.420 0.002
H47.3 Other disorders of optic disk
0.580 0.420 0.000
M13.8 Other specified arthritis
0.577 0.422 0.001
M13.1 Monoarthritis, not elsewhere classified
0.577 0.422 0.001
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure
0.577 0.423 0.000
A80-A89 Viral infections of the central nervous system
0.576 0.424 0.000
G11 Hereditary ataxia
0.576 0.424 0.000
E28.3 Primary ovarian failure
0.576 0.424 0.000
E11.2 With renal complications
0.575 0.425 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.575 0.425 0.000
E22.8 Other hyperfunction of pituitary gland
0.575 0.425 0.000
Y57 Other and unspecified drugs and medicaments
0.575 0.425 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.574 0.426 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.574 0.426 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.574 0.426 0.000
Q55 Other congenital malformations of male genital organs
0.574 0.426 0.000
Q52 Other congenital malformations of female genitalia
0.574 0.426 0.000
M79.0 Rheumatism, unspecified
0.574 0.426 0.000
Y82 Other and unspecified medical devices associated with adverse incidents
0.573 0.427 0.000
Y81 General- and plastic-surgery devices associated with adverse incidents
0.573 0.427 0.000
Y80 Physical medicine devices associated with adverse incidents
0.573 0.427 0.000
Y78 Radiological devices associated with adverse incidents
0.573 0.427 0.000
Y77 Ophthalmic devices associated with adverse incidents
0.573 0.427 0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents
0.573 0.427 0.000
Y75 Neurological devices associated with adverse incidents
0.573 0.427 0.000
Y74 General hospital and personal-use devices associated with adverse incidents
0.573 0.427 0.000
Y73 Gastro-enterology and urology devices associated with adverse incidents
0.573 0.427 0.000
Y72 Otorhinolaryngological devices associated with adverse incidents
0.573 0.427 0.000
Y71 Cardiovascular devices associated with adverse incidents
0.573 0.427 0.000
Y70 Anaesthesiology devices associated with adverse incidents
0.573 0.427 0.000
E13 Other specified diabetes mellitus
0.573 0.427 0.000
H18.4 Corneal degeneration
0.573 0.427 0.000
E11.3 With ophthalmic complications
0.573 0.427 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.570 0.430 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.570 0.430 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.569 0.431 0.000
Y09 Assault by unspecified means
0.569 0.431 0.000
Y08 Assault by other specified means
0.569 0.431 0.000
Y07 Other maltreatment syndromes
0.569 0.431 0.000
Y06 Neglect and abandonment
0.569 0.431 0.000
Y05 Sexual assault by bodily force
0.569 0.431 0.000
Y03 Assault by crashing of motor vehicle
0.569 0.431 0.000
Y02 Assault by pushing or placing victim before moving object
0.569 0.431 0.000
Y01 Assault by pushing from high place
0.569 0.431 0.000
Y00 Assault by blunt object
0.569 0.431 0.000
H47.7 Disorder of visual pathways, unspecified
0.569 0.431 0.000
H47.6 Disorders of visual cortex
0.569 0.431 0.000
H47.5 Disorders of other visual pathways
0.569 0.431 0.000
H47.4 Disorders of optic chiasm
0.569 0.431 0.000
H47.2 Optic atrophy
0.569 0.431 0.000
W84 Unspecified threat to breathing
0.568 0.431 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.568 0.432 0.000
V99 Unspecified transport accident
0.568 0.432 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.568 0.432 0.000
Q65 Congenital deformities of hip
0.568 0.432 0.000
G91.9 Hydrocephalus, unspecified
0.566 0.434 0.000
M10.98 Gout, unspecified (Other)
0.564 0.435 0.001
M10.95 Gout, unspecified (Pelvic region and thigh)
0.564 0.435 0.001
M10.94 Gout, unspecified (Hand)
0.564 0.435 0.001
M10.93 Gout, unspecified (Forearm)
0.564 0.435 0.001
M10.92 Gout, unspecified (Upper arm)
0.564 0.435 0.001
M10.91 Gout, unspecified (Shoulder region)
0.564 0.435 0.001
M10.90 Gout, unspecified (Multiple sites)
0.564 0.435 0.001
B65-B83 Helminthiases
0.564 0.436 0.000
F43 Reaction to severe stress, and adjustment disorders
0.564 0.436 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.563 0.437 0.000
H53-H54 Visual disturbances and blindness
0.563 0.437 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.562 0.438 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.562 0.438 0.000
Y40.8 Other systemic antibiotics
0.560 0.440 0.000
E28.9 Ovarian dysfunction, unspecified
0.559 0.440 0.000
E28.8 Other ovarian dysfunction
0.559 0.440 0.000
E28.1 Androgen excess
0.559 0.440 0.000
E28.0 Oestrogen excess
0.559 0.440 0.000
E23.7 Disorder of pituitary gland, unspecified
0.559 0.441 0.000
H18.9 Disorder of cornea, unspecified
0.559 0.441 0.000
A48 Other bacterial diseases, not elsewhere classified
0.559 0.441 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.559 0.441 0.000
E50-E64 Other nutritional deficiencies
0.555 0.444 0.000
G93.2 Benign intracranial hypertension
0.555 0.445 0.000
G56.1 Other lesions of median nerve
0.554 0.446 0.000
Y86 Sequelae of other accidents
0.554 0.446 0.000
H18.5 Hereditary corneal dystrophies
0.554 0.446 0.000
M89.8 Other specified disorders of bone
0.554 0.446 0.000
Y49.9 Psychotropic drug, unspecified
0.554 0.446 0.000
Y49.8 Other psychotropic drugs, not elsewhere classified
0.554 0.446 0.000
Y49.7 Psychostimulants with abuse potential
0.554 0.446 0.000
Y49.6 Psychodysleptics [hallucinogens]
0.554 0.446 0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics
0.554 0.446 0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics
0.554 0.446 0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants
0.554 0.446 0.000
Y49.0 Tricyclic and tetracyclic antidepressants
0.554 0.446 0.000
Chapter XXII Codes for special purposes
0.553 0.447 0.000
H21.8 Other specified disorders of iris and ciliary body
0.552 0.448 0.000
Y04.8 Other specified place
0.552 0.448 0.000
G95.2 Cord compression, unspecified
0.551 0.449 0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere
0.551 0.449 0.000
G94.2 Hydrocephalus in other diseases classified elsewhere
0.551 0.449 0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere
0.551 0.449 0.000
A40 Streptococcal septicaemia
0.551 0.449 0.000
E23.0 Hypopituitarism
0.551 0.449 0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified
0.550 0.449 0.000
Y41.4 Anthelminthics
0.550 0.449 0.000
Y41.3 Other antiprotozoal drugs
0.550 0.449 0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa
0.550 0.449 0.000
Y41.1 Antimycobacterial drugs
0.550 0.449 0.000
Y41.0 Sulphonamides
0.550 0.449 0.000
Y46.4 Iminostilbenes
0.550 0.450 0.000
H65-H75 Diseases of middle ear and mastoid
0.549 0.450 0.001
E14.3 With ophthalmic complications
0.549 0.450 0.000
V49.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident
0.549 0.451 0.000
E66.8 Other obesity
0.549 0.451 0.000
M14 Arthropathies in other diseases classified elsewhere
0.544 0.451 0.005
G52.9 Cranial nerve disorder, unspecified
0.549 0.451 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.548 0.452 0.000
H65 Nonsuppurative otitis media
0.548 0.452 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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