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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs62272723
log Bayes Factor = 13.2782
Chromosome 3   position 151,963,160  (GRCh37) Explore rs62272723 on Ensembl!
Variant rs62272723 is part of Cluster X0041

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
M13.9 Arthritis, unspecified
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M13 Other arthritis
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
O60-O75 Complications of labour and delivery
0.996 0.004 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.994 0.006 0.000
I49 Other cardiac arrhythmias
0.993 0.007 0.000
Chapter II Neoplasms
0.980 0.020 0.000
C15-C26 Malignant neoplasms of digestive organs
0.975 0.025 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.975 0.025 0.000
M13.94 Arthritis, unspecified (Hand)
0.975 0.025 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.968 0.032 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.966 0.034 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.964 0.036 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.964 0.036 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.964 0.036 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.963 0.037 0.000
O46.9 Antepartum haemorrhage, unspecified
0.958 0.042 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.950 0.050 0.000
G30-G32 Other degenerative diseases of the nervous system
0.947 0.053 0.000
M45-M49 Spondylopathies
0.947 0.053 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.945 0.055 0.000
I46 Cardiac arrest
0.943 0.057 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.942 0.058 0.000
C20 Malignant neoplasm of rectum
0.941 0.059 0.000
I49.3 Ventricular premature depolarisation
0.939 0.061 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.936 0.064 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.929 0.071 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.927 0.073 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.923 0.077 0.000
I05-I09 Chronic rheumatic heart diseases
0.923 0.077 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.921 0.079 0.000
G40-G47 Episodic and paroxysmal disorders
0.918 0.082 0.000
M05 Seropositive rheumatoid arthritis
0.916 0.084 0.000
I27 Other pulmonary heart diseases
0.916 0.084 0.000
I46.0 Cardiac arrest with successful resuscitation
0.910 0.090 0.000
I34 Nonrheumatic mitral valve disorders
0.899 0.101 0.000
T93 Sequelae of injuries of lower limb
0.896 0.104 0.000
M06 Other rheumatoid arthritis
0.895 0.105 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.893 0.107 0.000
T51 Toxic effect of alcohol
0.892 0.108 0.000
G40 Epilepsy
0.890 0.110 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.889 0.111 0.000
I72 Other aneurysm
0.889 0.111 0.000
Chapter XX External causes of morbidity and mortality
0.887 0.113 0.000
I60-I69 Cerebrovascular diseases
0.887 0.113 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.886 0.114 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.884 0.116 0.000
M47 Spondylosis
0.884 0.116 0.000
I49.0 Ventricular fibrillation and flutter
0.882 0.118 0.000
O32.1 Maternal care for breech presentation
0.879 0.121 0.000
O16 Unspecified maternal hypertension
0.879 0.121 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.876 0.124 0.000
G56 Mononeuropathies of upper limb
0.876 0.124 0.000
M80-M85 Disorders of bone density and structure
0.871 0.129 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.870 0.130 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.868 0.132 0.000
S00-S09 Injuries to the head
0.867 0.133 0.000
O85-O92 Complications predominantly related to the puerperium
0.866 0.134 0.000
I05 Rheumatic mitral valve diseases
0.865 0.135 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.863 0.137 0.000
Chapter VII Diseases of the eye and adnexa
0.862 0.138 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.859 0.141 0.000
O63 Long labour
0.857 0.142 0.000
O47 False labour
0.857 0.143 0.000
O48 Prolonged pregnancy
0.856 0.143 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.856 0.144 0.000
M47.8 Other spondylosis
0.856 0.144 0.000
I49.9 Cardiac arrhythmia, unspecified
0.855 0.145 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.855 0.145 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.853 0.147 0.000
G56.0 Carpal tunnel syndrome
0.853 0.147 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.850 0.150 0.000
M48 Other spondylopathies
0.848 0.152 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.848 0.152 0.000
D37.4 Colon
0.846 0.154 0.000
T51.0 Ethanol
0.844 0.156 0.000
I44 Atrioventricular and left bundle-branch block
0.843 0.157 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.837 0.163 0.000
M40-M43 Deforming dorsopathies
0.837 0.163 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.833 0.167 0.000
D00-D09 In situ neoplasms
0.833 0.167 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.832 0.168 0.000
I27.0 Primary pulmonary hypertension
0.825 0.175 0.000
O00-O08 Pregnancy with abortive outcome
0.825 0.175 0.000
S01 Open wound of head
0.824 0.176 0.000
I26 Pulmonary embolism
0.823 0.177 0.000
I49.8 Other specified cardiac arrhythmias
0.821 0.179 0.000
O62 Abnormalities of forces of labour
0.821 0.179 0.000
C16 Malignant neoplasm of stomach
0.818 0.182 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.818 0.182 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.817 0.183 0.000
S70-S79 Injuries to the hip and thigh
0.816 0.184 0.000
M13.98 Arthritis, unspecified (Other)
0.814 0.185 0.000
I45 Other conduction disorders
0.813 0.187 0.000
O70 Perineal laceration during delivery
0.811 0.189 0.000
G57 Mononeuropathies of lower limb
0.809 0.191 0.000
G90-G99 Other disorders of the nervous system
0.808 0.192 0.000
I72.0 Aneurysm of carotid artery
0.808 0.192 0.000
S90-S99 Injuries to the ankle and foot
0.807 0.193 0.000
O80-O84 Delivery
0.805 0.195 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.804 0.196 0.000
I42 Cardiomyopathy
0.804 0.196 0.000
S01.1 Open wound of eyelid and periocular area
0.803 0.197 0.000
O20 Haemorrhage in early pregnancy
0.801 0.199 0.000
O42 Premature rupture of membranes
0.801 0.199 0.000
I05.9 Mitral valve disease, unspecified
0.799 0.201 0.000
C81 Hodgkin's disease
0.798 0.202 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.796 0.204 0.000
T91 Sequelae of injuries of neck and trunk
0.795 0.205 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.795 0.205 0.000
S10-S19 Injuries to the neck
0.794 0.206 0.000
I27.2 Other secondary pulmonary hypertension
0.788 0.212 0.000
G30 Alzheimer's disease
0.788 0.212 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.788 0.212 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.788 0.212 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.787 0.213 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.783 0.217 0.000
G20-G26 Extrapyramidal and movement disorders
0.783 0.217 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.782 0.218 0.000
O43 Placental disorders
0.782 0.218 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.781 0.219 0.000
I49.1 Atrial premature depolarisation
0.778 0.221 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.778 0.222 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.778 0.222 0.000
M48.0 Spinal stenosis
0.777 0.223 0.000
M11 Other crystal arthropathies
0.776 0.224 0.000
Chapter XXII Codes for special purposes
0.774 0.226 0.000
Chapter V Mental and behavioural disorders
0.774 0.226 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.772 0.228 0.000
O70.0 First degree perineal laceration during delivery
0.772 0.228 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.771 0.229 0.000
G11 Hereditary ataxia
0.771 0.229 0.000
I77 Other disorders of arteries and arterioles
0.770 0.230 0.000
M47.86 Other spondylosis (Lumbar region)
0.769 0.231 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.768 0.232 0.000
S40-S49 Injuries to the shoulder and upper arm
0.768 0.232 0.000
M84 Disorders of continuity of bone
0.765 0.235 0.000
O63.1 Prolonged second stage (of labour)
0.762 0.238 0.000
I49.4 Other and unspecified premature depolarisation
0.762 0.238 0.000
I63 Cerebral infarction
0.762 0.238 0.000
I34.0 Mitral (valve) insufficiency
0.760 0.240 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.760 0.240 0.000
Chapter VIII Diseases of the ear and mastoid process
0.759 0.241 0.000
D03 Melanoma in situ
0.759 0.241 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.757 0.243 0.000
M13.0 Polyarthritis, unspecified
0.757 0.243 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.756 0.243 0.000
G40.9 Epilepsy, unspecified
0.756 0.244 0.000
T56 Toxic effect of metals
0.755 0.245 0.000
I67 Other cerebrovascular diseases
0.755 0.245 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.754 0.246 0.000
M06.0 Seronegative rheumatoid arthritis
0.752 0.248 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.751 0.249 0.000
T42.4 Benzodiazepines
0.751 0.249 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.750 0.250 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.748 0.252 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.748 0.252 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.747 0.253 0.000
M86-M90 Other osteopathies
0.746 0.254 0.000
G70-G73 Diseases of myoneural junction and muscle
0.745 0.255 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.744 0.256 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.739 0.261 0.000
H04 Disorders of lachrymal system
0.738 0.262 0.000
H50 Other strabismus
0.738 0.262 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.736 0.264 0.000
G12 Spinal muscular atrophy and related syndromes
0.736 0.264 0.000
I50 Heart failure
0.736 0.264 0.000
I72.8 Aneurysm of other specified arteries
0.735 0.265 0.000
O66 Other obstructed labour
0.734 0.265 0.000
M00-M03 Infectious arthropathies
0.734 0.266 0.000
C25 Malignant neoplasm of pancreas
0.734 0.266 0.000
H43-H45 Disorders of vitreous body and globe
0.732 0.268 0.000
O02 Other abnormal products of conception
0.731 0.268 0.000
G41 Status epilepticus
0.731 0.269 0.000
G58 Other mononeuropathies
0.731 0.269 0.000
H04.2 Epiphora
0.731 0.269 0.000
C18 Malignant neoplasm of colon
0.731 0.269 0.000
T66-T78 Other and unspecified effects of external causes
0.730 0.270 0.000
I51 Complications and ill-defined descriptions of heart disease
0.730 0.270 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.728 0.272 0.000
O20.0 Threatened abortion
0.727 0.273 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.726 0.274 0.000
I60 Subarachnoid haemorrhage
0.725 0.275 0.000
T92 Sequelae of injuries of upper limb
0.725 0.275 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.724 0.276 0.000
M06.3 Rheumatoid nodule
0.724 0.276 0.000
O61 Failed induction of labour
0.723 0.277 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.722 0.278 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.722 0.278 0.000
O86 Other puerperal infections
0.721 0.279 0.000
I44.3 Other and unspecified atrioventricular block
0.719 0.280 0.000
I78 Diseases of capillaries
0.719 0.281 0.000
D37.5 Rectum
0.719 0.281 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.718 0.282 0.000
C16.0 Cardia
0.718 0.282 0.000
O28 Abnormal findings on antenatal screening of mother
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M14 Arthropathies in other diseases classified elsewhere
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
M13.93 Arthritis, unspecified (Forearm)
0.717 0.283 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M13.8 Other specified arthritis
0.717 0.283 0.000
M13.1 Monoarthritis, not elsewhere classified
0.717 0.283 0.000
O45 Premature separation of placenta [abruptio placentae]
0.716 0.284 0.000
O33 Maternal care for known or suspected disproportion
0.716 0.284 0.000
O31 Complications specific to multiple gestation
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
O74 Complications of anaesthesia during labour and delivery
0.714 0.286 0.000
O71 Other obstetric trauma
0.714 0.286 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.714 0.286 0.000
O60 Preterm delivery
0.714 0.286 0.000
O69.0 Labour and delivery complicated by prolapse of cord
0.714 0.286 0.000
O67.9 Intrapartum haemorrhage, unspecified
0.714 0.286 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.714 0.286 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.713 0.287 0.000
I49.2 Junctional premature depolarisation
0.712 0.288 0.000
I30 Acute pericarditis
0.712 0.288 0.000
I27.9 Pulmonary heart disease, unspecified
0.711 0.289 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.710 0.290 0.000
C15 Malignant neoplasm of oesophagus
0.710 0.290 0.000
I31 Other diseases of pericardium
0.708 0.292 0.000
Y00-Y09 Assault
0.708 0.292 0.000
I36 Nonrheumatic tricuspid valve disorders
0.706 0.294 0.000
O73 Retained placenta and membranes, without haemorrhage
0.705 0.295 0.000
O30 Multiple gestation
0.704 0.296 0.000
I77.6 Arteritis, unspecified
0.704 0.296 0.000
H50.0 Convergent concomitant strabismus
0.703 0.297 0.000
M50-M54 Other dorsopathies
0.703 0.297 0.000
M48.06 Spinal stenosis (Lumbar region)
0.703 0.297 0.000
T93.1 Sequelae of fracture of femur
0.703 0.297 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.703 0.297 0.000
S01.9 Open wound of head, part unspecified
0.703 0.297 0.000
O32.2 Maternal care for transverse and oblique lie
0.702 0.297 0.000
O92 Other disorders of breast and lactation associated with childbirth
0.703 0.297 0.000
C81.9 Hodgkin's disease, unspecified
0.702 0.298 0.000
Y52 Agents primarily affecting the cardiovascular system
0.702 0.298 0.000
M43 Other deforming dorsopathies
0.702 0.298 0.000
I49.5 Sick sinus syndrome
0.701 0.299 0.000
O44 Placenta praevia
0.701 0.299 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.701 0.299 0.000
M47.1 Other spondylosis with myelopathy
0.701 0.299 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.700 0.300 0.000
T51.9 Alcohol, unspecified
0.700 0.300 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.700 0.300 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.699 0.301 0.000
C21 Malignant neoplasm of anus and anal canal
0.699 0.301 0.000
C17 Malignant neoplasm of small intestine
0.699 0.301 0.000
C23 Malignant neoplasm of gallbladder
0.699 0.301 0.000
O46.8 Other antepartum haemorrhage
0.699 0.301 0.000
O46.0 Antepartum haemorrhage with coagulation defect
0.699 0.301 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.699 0.301 0.000
V80-V89 Other land transport accidents
0.699 0.301 0.000
T79-T79 Certain early complications of trauma
0.698 0.302 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.698 0.302 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.696 0.303 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.696 0.304 0.000
M06.9 Rheumatoid arthritis, unspecified
0.696 0.304 0.000
M82 Osteoporosis in diseases classified elsewhere
0.695 0.305 0.000
T93.0 Sequelae of open wound of lower limb
0.695 0.305 0.000
S72 Fracture of femur
0.695 0.305 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.694 0.306 0.000
O32.8 Maternal care for other malpresentation of foetus
0.694 0.306 0.000
O32.6 Maternal care for compound presentation
0.694 0.306 0.000
O32.4 Maternal care for high head at term
0.694 0.306 0.000
O32.3 Maternal care for face, brow and chin presentation
0.694 0.306 0.000
O32.0 Maternal care for unstable lie
0.694 0.306 0.000
O15 Eclampsia
0.693 0.307 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.693 0.307 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.693 0.307 0.000
G44 Other headache syndromes
0.693 0.307 0.000
I28 Other diseases of pulmonary vessels
0.691 0.308 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.691 0.309 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.691 0.309 0.000
G52 Disorders of other cranial nerves
0.691 0.309 0.000
I62 Other nontraumatic intracranial haemorrhage
0.690 0.309 0.000
I34.1 Mitral (valve) prolapse
0.690 0.310 0.000
I42.9 Cardiomyopathy, unspecified
0.690 0.310 0.000
C64-C68 Malignant neoplasms of urinary tract
0.689 0.311 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.689 0.311 0.000
I33 Acute and subacute endocarditis
0.689 0.311 0.000
G54 Nerve root and plexus disorders
0.688 0.312 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.686 0.314 0.000
S31 Open wound of abdomen, lower back and pelvis
0.686 0.314 0.000
O34.1 Maternal care for tumour of corpus uteri
0.685 0.315 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.684 0.316 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.684 0.316 0.000
M91-M94 Chondropathies
0.684 0.316 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.683 0.317 0.000
I05.2 Mitral stenosis with insufficiency
0.683 0.317 0.000
I45.4 Nonspecific intraventricular block
0.682 0.317 0.000
I72.4 Aneurysm of artery of lower extremity
0.682 0.318 0.000
O03 Spontaneous abortion
0.682 0.318 0.000
T98 Sequelae of other and unspecified effects of external causes
0.681 0.319 0.000
T95 Sequelae of burns, corrosions and frostbite
0.681 0.319 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.681 0.319 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.681 0.319 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.681 0.319 0.000
C81.1 Nodular sclerosis
0.681 0.319 0.000
S32 Fracture of lumbar spine and pelvis
0.680 0.320 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.679 0.321 0.000
M49 Spondylopathies in diseases classified elsewhere
0.679 0.321 0.000
I44.2 Atrioventricular block, complete
0.679 0.321 0.000
G40.8 Other epilepsy
0.678 0.322 0.000
I46.1 Sudden cardiac death, so described
0.676 0.323 0.000
G20 Parkinson's disease
0.676 0.324 0.000
O40 Polyhydramnios
0.676 0.324 0.000
T65 Toxic effect of other and unspecified substances
0.675 0.324 0.000
T62 Toxic effect of other noxious substances eaten as food
0.675 0.324 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.675 0.324 0.000
T60 Toxic effect of pesticides
0.675 0.324 0.000
T59 Toxic effect of other gases, fumes and vapours
0.675 0.324 0.000
T57 Toxic effect of other inorganic substances
0.675 0.324 0.000
T54 Toxic effect of corrosive substances
0.675 0.324 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.675 0.324 0.000
T52 Toxic effect of organic solvents
0.675 0.324 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.675 0.324 0.000
T58 Toxic effect of carbon monoxide
0.675 0.324 0.000
T55 Toxic effect of soaps and detergents
0.675 0.324 0.000
I45.5 Other specified heart block
0.675 0.325 0.000
I74 Arterial embolism and thrombosis
0.675 0.325 0.000
G30.9 Alzheimer's disease, unspecified
0.674 0.326 0.000
H10-H13 Disorders of conjunctiva
0.674 0.326 0.000
O62.3 Precipitate labour
0.672 0.328 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.672 0.328 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.671 0.328 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.671 0.329 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.671 0.329 0.000
I07 Rheumatic tricuspid valve diseases
0.670 0.329 0.000
G11.4 Hereditary spastic paraplegia
0.670 0.330 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.670 0.330 0.000
X50-X57 Overexertion, travel and privation
0.669 0.330 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.668 0.332 0.000
O14.1 Severe preeclampsia
0.668 0.332 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.667 0.333 0.000
Y48 Anaesthetics and therapeutic gases
0.667 0.333 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.666 0.334 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.666 0.334 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.666 0.334 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.666 0.334 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.666 0.334 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.666 0.334 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.666 0.334 0.000
T36 Poisoning by systemic antibiotics
0.666 0.334 0.000
G31.8 Other specified degenerative diseases of nervous system
0.665 0.334 0.000
O21 Excessive vomiting in pregnancy
0.665 0.335 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.665 0.335 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.665 0.335 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.665 0.335 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.664 0.335 0.000
I44.1 Atrioventricular block, second degree
0.664 0.336 0.000
G51 Facial nerve disorders
0.664 0.336 0.000
S20-S29 Injuries to the thorax
0.664 0.336 0.000
O63.9 Long labour, unspecified
0.663 0.337 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.663 0.337 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.663 0.337 0.000
H80-H83 Diseases of inner ear
0.663 0.337 0.000
I70 Atherosclerosis
0.663 0.337 0.000
Y57 Other and unspecified drugs and medicaments
0.662 0.338 0.000
D37.6 Liver, gallbladder and bile ducts
0.661 0.338 0.000
I09 Other rheumatic heart diseases
0.661 0.338 0.000
I06 Rheumatic aortic valve diseases
0.661 0.338 0.000
I08 Multiple valve diseases
0.661 0.339 0.000
I05.0 Mitral stenosis
0.661 0.339 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.660 0.340 0.000
G57.1 Meralgia paraesthetica
0.660 0.340 0.000
G93 Other disorders of brain
0.660 0.340 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.660 0.340 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.658 0.342 0.000
O02.1 Missed abortion
0.658 0.342 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.658 0.342 0.000
M46 Other inflammatory spondylopathies
0.657 0.342 0.000
M05.8 Other seropositive rheumatoid arthritis
0.657 0.343 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.657 0.343 0.000
M05.2 Rheumatoid vasculitis
0.657 0.343 0.000
M05.1 Rheumatoid lung disease
0.657 0.343 0.000
M05.0 Felty's syndrome
0.657 0.343 0.000
I27.8 Other specified pulmonary heart diseases
0.656 0.343 0.000
I27.1 Kyphoscoliotic heart disease
0.656 0.343 0.000
T43.2 Other and unspecified antidepressants
0.657 0.343 0.000
Y54.3 Benzothiadiazine derivatives
0.654 0.345 0.000
F30-F39 Mood [affective] disorders
0.654 0.346 0.000
H43 Disorders of vitreous body
0.653 0.347 0.000
I67.1 Cerebral aneurysm, nonruptured
0.653 0.347 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.652 0.348 0.000
D37.7 Other digestive organs
0.651 0.349 0.000
I67.2 Cerebral atherosclerosis
0.649 0.351 0.000
T93.2 Sequelae of other fractures of lower limb
0.649 0.351 0.000
G96 Other disorders of central nervous system
0.649 0.351 0.000
O81 Single delivery by forceps and vacuum extractor
0.648 0.351 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.648 0.352 0.000
D37.1 Stomach
0.647 0.353 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.647 0.353 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.646 0.353 0.000
O72 Postpartum haemorrhage
0.645 0.355 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.645 0.355 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.645 0.355 0.000
G50 Disorders of trigeminal nerve
0.644 0.355 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.644 0.356 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.644 0.356 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.644 0.356 0.000
C34 Malignant neoplasm of bronchus and lung
0.644 0.356 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.644 0.356 0.000
S72.0 Fracture of neck of femur
0.643 0.357 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.642 0.357 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.642 0.357 0.000
T93.4 Sequelae of injury of nerve of lower limb
0.642 0.357 0.000
C92 Myeloid leukaemia
0.642 0.358 0.000
I45.8 Other specified conduction disorders
0.641 0.358 0.000
M06.8 Other specified rheumatoid arthritis
0.641 0.358 0.000
M06.4 Inflammatory polyarthropathy
0.641 0.358 0.000
M06.2 Rheumatoid bursitis
0.641 0.358 0.000
M06.1 Adult-onset Still's disease
0.641 0.358 0.000
C69 Malignant neoplasm of eye and adnexa
0.641 0.359 0.000
O82 Single delivery by Caesarean section
0.641 0.359 0.000
X20-X29 Contact with venomous animals and plants
0.641 0.359 0.000
M84.0 Malunion of fracture
0.641 0.359 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.640 0.360 0.000
G14 Postpolio syndrome
0.640 0.360 0.000
G10 Huntington's disease
0.640 0.360 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.640 0.360 0.000
S42 Fracture of shoulder and upper arm
0.640 0.360 0.000
T51.8 Other alcohols
0.639 0.361 0.000
T51.3 Fusel oil
0.639 0.361 0.000
T51.2 2-Propanol
0.639 0.361 0.000
T51.1 Methanol
0.639 0.361 0.000
D48.5 Skin
0.639 0.361 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.639 0.361 0.000
T63 Toxic effect of contact with venomous animals
0.639 0.361 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.639 0.361 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.638 0.362 0.000
G40.5 Special epileptic syndromes
0.638 0.362 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.638 0.362 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.638 0.362 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.638 0.362 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.638 0.362 0.000
S01.4 Open wound of cheek and temporomandibular area
0.638 0.362 0.000
S02 Fracture of skull and facial bones
0.638 0.362 0.000
H55-H59 Other disorders of eye and adnexa
0.638 0.362 0.000
D37.9 Digestive organ, unspecified
0.637 0.363 0.000
D37.3 Appendix
0.637 0.363 0.000
D37.2 Small intestine
0.637 0.363 0.000
S92 Fracture of foot, except ankle
0.637 0.363 0.000
I72.9 Aneurysm of unspecified site
0.637 0.363 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.637 0.363 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.637 0.363 0.000
I72.3 Aneurysm of iliac artery
0.637 0.363 0.000
I72.2 Aneurysm of renal artery
0.637 0.363 0.000
I72.1 Aneurysm of artery of upper extremity
0.637 0.363 0.000
M80 Osteoporosis with pathological fracture
0.636 0.363 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.636 0.364 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.636 0.364 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.636 0.364 0.000
Y35-Y36 Legal intervention and operations of war
0.636 0.364 0.000
Y10-Y34 Event of undetermined intent
0.636 0.364 0.000
X85-X99 Assault
0.636 0.364 0.000
X60-X84 Intentional self-harm
0.636 0.364 0.000
X30-X39 Exposure to forces of nature
0.636 0.364 0.000
X10-X19 Contact with heat and hot substances
0.636 0.364 0.000
X00-X09 Exposure to smoke, fire and flames
0.636 0.364 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.636 0.364 0.000
W75-W84 Other accidental threats to breathing
0.636 0.364 0.000
W65-W74 Accidental drowning and submersion
0.636 0.364 0.000
W50-W64 Exposure to animate mechanical forces
0.636 0.364 0.000
V98-V99 Other and unspecified transport accidents
0.636 0.364 0.000
V95-V97 Air and space transport accidents
0.636 0.364 0.000
V90-V94 Water transport accidents
0.636 0.364 0.000
V70-V79 Bus occupant injured in transport accident
0.636 0.364 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.636 0.364 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.636 0.364 0.000
V40-V49 Car occupant injured in transport accident
0.636 0.364 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.636 0.364 0.000
V01-V09 Pedestrian injured in transport accident
0.636 0.364 0.000
C18.7 Sigmoid colon
0.636 0.364 0.000
O29 Complications of anaesthesia during pregnancy
0.635 0.364 0.000
O23 Infections of genito-urinary tract in pregnancy
0.635 0.364 0.000
O22 Venous complications in pregnancy
0.635 0.364 0.000
O25 Malnutrition in pregnancy
0.635 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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