TreeWAS – Variant ID: rs62355904

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
I25 Chronic ischaemic heart disease	1.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
M50-M54 Other dorsopathies	1.000	0.000
M54.5 Low back pain	1.000	0.000
M54 Dorsalgia	1.000	0.000
M20-M25 Other joint disorders	1.000	0.000
I21 Acute myocardial infarction	0.999	0.001
I25.8 Other forms of chronic ischaemic heart disease	0.997	0.003
I25.1 Atherosclerotic heart disease	0.997	0.003
M54.59 Low back pain (Site unspecified)	0.995	0.005
I21.9 Acute myocardial infarction, unspecified	0.993	0.007
M20 Acquired deformities of fingers and toes	0.991	0.009
M54.56 Low back pain (Lumbar region)	0.991	0.009
I10-I15 Hypertensive diseases	0.987	0.013
I70-I79 Diseases of arteries, arterioles and capillaries	0.983	0.017
I25.2 Old myocardial infarction	0.982	0.018
I10 Essential (primary) hypertension	0.974	0.026
M20.1 Hallux valgus (acquired)	0.973	0.027
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.960	0.040
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.955	0.045
M80-M85 Disorders of bone density and structure	0.944	0.056
Chapter IV Endocrine, nutritional and metabolic diseases	0.938	0.062
I20 Angina pectoris	0.936	0.064
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.934	0.066
D69 Purpura and other haemorrhagic conditions	0.932	0.068
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.931	0.069
I21.1 Acute transmural myocardial infarction of inferior wall	0.929	0.071
E70-E90 Metabolic disorders	0.928	0.072
E78.0 Pure hypercholesterolaemia	0.922	0.078
I77 Other disorders of arteries and arterioles	0.921	0.079
D68 Other coagulation defects	0.919	0.081
E78.5 Hyperlipidaemia, unspecified	0.916	0.084
D69.6 Thrombocytopenia, unspecified	0.914	0.086
M25 Other joint disorders, not elsewhere classified	0.912	0.088
S70-S79 Injuries to the hip and thigh	0.904	0.096
M45-M49 Spondylopathies	0.901	0.099
I71 Aortic aneurysm and dissection	0.885	0.115
Chapter XII Diseases of the skin and subcutaneous tissue	0.880	0.120
S72 Fracture of femur	0.880	0.120
M24 Other specific joint derangements	0.879	0.121
I25.3 Aneurysm of heart	0.876	0.124
M05-M14 Inflammatory polyarthropathies	0.875	0.125
M35 Other systemic involvement of connective tissue	0.872	0.128
S00-S09 Injuries to the head	0.870	0.130
S72.0 Fracture of neck of femur	0.857	0.143
M31 Other necrotising vasculopathies	0.857	0.143
I25.9 Chronic ischaemic heart disease, unspecified	0.856	0.144
I22 Subsequent myocardial infarction	0.847	0.153
I72 Other aneurysm	0.846	0.154
I70 Atherosclerosis	0.845	0.155
Chapter XX External causes of morbidity and mortality	0.845	0.155
S72.00 Fracture of neck of femur (closed)	0.841	0.159
D68.2 Hereditary deficiency of other clotting factors	0.841	0.159
L40-L45 Papulosquamous disorders	0.836	0.164
I77.1 Stricture of artery	0.835	0.165
M81 Osteoporosis without pathological fracture	0.833	0.167
M20.4 Other hammer toe(s) (acquired)	0.832	0.168
M25.7 Osteophyte	0.829	0.171
M84 Disorders of continuity of bone	0.820	0.180
M54.57 Low back pain (Lumbosacral region)	0.820	0.180
I21.4 Acute subendocardial myocardial infarction	0.818	0.182
Chapter VI Diseases of the nervous system	0.818	0.182
M54.2 Cervicalgia	0.814	0.186
I21.3 Acute transmural myocardial infarction of unspecified site	0.811	0.189
M86-M90 Other osteopathies	0.811	0.189
L40 Psoriasis	0.808	0.192
M35.3 Polymyalgia rheumatica	0.805	0.195
Chapter V Mental and behavioural disorders	0.801	0.199
I21.2 Acute transmural myocardial infarction of other sites	0.798	0.202
I20.9 Angina pectoris, unspecified	0.795	0.205
M20.5 Other deformities of toe(s) (acquired)	0.790	0.210
M34 Systemic sclerosis	0.787	0.213
I25.5 Ischaemic cardiomyopathy	0.786	0.214
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.786	0.214
I12 Hypertensive renal disease	0.785	0.215
S06 Intracranial injury	0.785	0.215
M70-M79 Other soft tissue disorders	0.784	0.216
I20.0 Unstable angina	0.783	0.217
S80-S89 Injuries to the knee and lower leg	0.781	0.219
M25.77 Osteophyte (Ankle and foot)	0.777	0.223
M24.1 Other articular cartilage disorders	0.774	0.226
I20.8 Other forms of angina pectoris	0.772	0.228
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.772	0.228
M13 Other arthritis	0.772	0.228
L40.9 Psoriasis, unspecified	0.772	0.228
M48 Other spondylopathies	0.771	0.229
M50 Cervical disk disorders	0.770	0.230
M21 Other acquired deformities of limbs	0.770	0.230
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.768	0.232
Chapter XV Pregnancy, childbirth and the puerperium	0.764	0.236
D68.6 Other Thrombophilia	0.763	0.237
M54.6 Pain in thoracic spine	0.763	0.237
M54.4 Lumbago with sciatica	0.762	0.238
Chapter XXII Codes for special purposes	0.760	0.240
G50-G59 Nerve, nerve root and plexus disorders	0.760	0.240
T15-T19 Effects of foreign body entering through natural orifice	0.758	0.242
T79-T79 Certain early complications of trauma	0.757	0.243
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.756	0.244
M31.6 Other giant cell arteritis	0.754	0.246
I77.9 Disorder of arteries and arterioles, unspecified	0.752	0.248
M79 Other soft tissue disorders, not elsewhere classified	0.750	0.250
M20.0 Deformity of finger(s)	0.750	0.250
M91-M94 Chondropathies	0.747	0.253
M20.6 Acquired deformity of toe(s), unspecified	0.744	0.256
L80-L99 Other disorders of the skin and subcutaneous tissue	0.744	0.256
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.743	0.257
E00-E07 Disorders of thyroid gland	0.742	0.258
I77.0 Arteriovenous fistula, acquired	0.741	0.259
M54.1 Radiculopathy	0.737	0.263
M53 Other dorsopathies, not elsewhere classified	0.736	0.264
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.733	0.267
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.730	0.270
D68.5 Primary Thrombophilia	0.729	0.271
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.729	0.271
W00-W19 Falls	0.726	0.274
M84.1 Nonunion of fracture [pseudarthrosis]	0.726	0.274
M47 Spondylosis	0.724	0.276
M85 Other disorders of bone density and structure	0.721	0.279
D68.9 Coagulation defect, unspecified	0.719	0.281
M54.3 Sciatica	0.719	0.281
I25.6 Silent myocardial ischaemia	0.717	0.283
I25.4 Coronary artery aneurysm	0.717	0.283
I25.0 Atherosclerotic cardiovascular disease, so described	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M54.55 Low back pain (Thoracolumbar region)	0.717	0.283
M54.54 Low back pain-Thoracic	0.717	0.283
M54.53 Low back pain-Cervicothoracic	0.717	0.283
M54.52 Low back pain-Cervical	0.717	0.283
M54.51 Low back pain-Occipit-atl-axl	0.717	0.283
M54.50 Low back pain (Multiple sites in spine)	0.717	0.283
M54.8 Other dorsalgia	0.717	0.283
M54.0 Panniculitis affecting regions of neck and back	0.717	0.283
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283
M33 Dermatopolymyositis	0.717	0.283
M32 Systemic lupus erythematosus	0.717	0.283
M30 Polyarteritis nodosa and related conditions	0.717	0.283
M81.9 Osteoporosis, unspecified	0.717	0.283
I21.X Presumed acute myicardial infaction (unconfirmed)	0.716	0.284
F10 Mental and behavioural disorders due to use of alcohol	0.713	0.287
M20.3 Other deformity of hallux (acquired)	0.711	0.289
I70.2 Atherosclerosis of arteries of the extremities	0.711	0.289
I15 Secondary hypertension	0.707	0.292
I13 Hypertensive heart and renal disease	0.707	0.292
I11 Hypertensive heart disease	0.707	0.292
Chapter VIII Diseases of the ear and mastoid process	0.706	0.294
D80-D89 Certain disorders involving the immune mechanism	0.706	0.294
Chapter XXI Factors influencing health status and contact with health services	0.705	0.295
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.705	0.295
M07 Psoriatic and enteropathic arthropathies	0.703	0.297
S50-S59 Injuries to the elbow and forearm	0.701	0.299
E20-E35 Disorders of other endocrine glands	0.700	0.300
M13.9 Arthritis, unspecified	0.699	0.301
M24.16 Other articular cartilage disorders (Lower leg)	0.698	0.301
M25.6 Stiffness of joint, not elsewhere classified	0.697	0.303
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.696	0.304
M35.7 Hypermobility syndrome	0.696	0.304
M80 Osteoporosis with pathological fracture	0.695	0.305
M25.8 Other specified joint disorders	0.695	0.305
I20.1 Angina pectoris with documented spasm	0.694	0.306
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.693	0.307
M25.3 Other instability of joint	0.693	0.307
E88 Other metabolic disorders	0.691	0.309
I22.9 Subsequent myocardial infarction of unspecified site	0.690	0.310
Z95 Presence of cardiac and vascular implants and grafts	0.689	0.311
D55-D59 Haemolytic anaemias	0.688	0.312
S01 Open wound of head	0.688	0.312
M79.6 Pain in limb	0.688	0.312
S72.4 Fracture of lower end of femur	0.687	0.313
M45 Ankylosing spondylitis	0.686	0.314
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.686	0.314
D67 Hereditary factor IX deficiency	0.685	0.315
D66 Hereditary factor VIII deficiency	0.685	0.315
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.685	0.315
S06.5 Traumatic subdural haemorrhage	0.685	0.315
I72.4 Aneurysm of artery of lower extremity	0.683	0.317
D69.3 Idiopathic thrombocytopenic purpura	0.683	0.317
I84 Haemorrhoids	0.682	0.318
M25.4 Effusion of joint	0.682	0.318
M54.22 Cervicalgia (Cervical region)	0.681	0.319
T66-T78 Other and unspecified effects of external causes	0.680	0.319
S79 Other and unspecified injuries of hip and thigh	0.679	0.321
S00 Superficial injury of head	0.678	0.322
M83 Adult osteomalacia	0.677	0.323
M82 Osteoporosis in diseases classified elsewhere	0.677	0.323
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.676	0.324
S05 Injury of eye and orbit	0.676	0.324
S80 Superficial injury of lower leg	0.675	0.325
M24.0 Loose body in joint	0.674	0.326
M20.2 Hallux rigidus	0.673	0.327
M81.4 Drug-induced osteoporosis	0.670	0.329
G56 Mononeuropathies of upper limb	0.670	0.330
T33-T35 Frostbite	0.670	0.330
T26-T28 Burns and corrosions confined to eye and internal organs	0.670	0.330
T20-T25 Burns and corrosions of external body surface, specified by site	0.670	0.330
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.670	0.330
T00-T07 Injuries involving multiple body regions	0.670	0.330
S10-S19 Injuries to the neck	0.670	0.330
I72.0 Aneurysm of carotid artery	0.669	0.331
S72.3 Fracture of shaft of femur	0.669	0.331
Z95.5 Presence of coronary angioplasty implant and graft	0.668	0.332
I70.0 Atherosclerosis of aorta	0.668	0.332
D69.9 Haemorrhagic condition, unspecified	0.668	0.332
D69.8 Other specified haemorrhagic conditions	0.668	0.332
D69.5 Secondary thrombocytopenia	0.668	0.332
D69.4 Other primary thrombocytopenia	0.668	0.332
D69.2 Other nonthrombocytopenic purpura	0.668	0.332
D69.1 Qualitative platelet defects	0.668	0.332
D69.0 Allergic purpura	0.668	0.332
E78.9 Disorder of lipoprotein metabolism, unspecified	0.668	0.332
E78.8 Other disorders of lipoprotein metabolism	0.668	0.332
E78.6 Lipoprotein deficiency	0.668	0.332
E78.4 Other hyperlipidaemia	0.668	0.332
E78.3 Hyperchylomicronaemia	0.668	0.332
E78.1 Pure hyperglyceridaemia	0.668	0.332
I22.8 Subsequent myocardial infarction of other sites	0.667	0.333
I24 Other acute ischaemic heart diseases	0.665	0.335
E85 Amyloidosis	0.665	0.335
E84 Cystic fibrosis	0.665	0.335
E79 Disorders of purine and pyrimidine metabolism	0.665	0.335
E77 Disorders of glycoprotein metabolism	0.665	0.335
E76 Disorders of glycosaminoglycan metabolism	0.665	0.335
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.665	0.335
E74 Other disorders of carbohydrate metabolism	0.665	0.335
E73 Lactose intolerance	0.665	0.335
E72 Other disorders of amino-acid metabolism	0.665	0.335
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.665	0.335
E70 Disorders of aromatic amino-acid metabolism	0.665	0.335
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.665	0.335
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.664	0.336
I95-I99 Other and unspecified disorders of the circulatory system	0.664	0.336
M46 Other inflammatory spondylopathies	0.664	0.336
M06 Other rheumatoid arthritis	0.664	0.336
M48.0 Spinal stenosis	0.663	0.337
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.663	0.337
E40-E46 Malnutrition	0.662	0.338
I77.8 Other specified disorders of arteries and arterioles	0.660	0.339
I77.5 Necrosis of artery	0.660	0.339
I77.4 Coeliac artery compression syndrome	0.660	0.339
I77.3 Arterial fibromuscular dysplasia	0.660	0.339
I77.2 Rupture of artery	0.660	0.339
D68.4 Acquired coagulation factor deficiency	0.659	0.341
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.659	0.341
D68.1 Hereditary factor XI deficiency	0.659	0.341
D68.0 Von Willebrand's disease	0.659	0.341
E78.2 Mixed hyperlipidaemia	0.657	0.343
D68.8 Other specified coagulation defects	0.657	0.343
M87 Osteonecrosis	0.655	0.345
M25.72 Osteophyte (Upper arm)	0.654	0.346
L92 Granulomatous disorders of skin and subcutaneous tissue	0.654	0.346
M25.9 Joint disorder, unspecified	0.654	0.346
M25.2 Flail joint	0.654	0.346
M25.1 Fistula of joint	0.654	0.346
M25.0 Haemarthrosis	0.654	0.346
I72.8 Aneurysm of other specified arteries	0.651	0.349
S09 Other and unspecified injuries of head	0.651	0.349
O94-O99 Other obstetric conditions, not elsewhere classified	0.651	0.349
Z95.8 Presence of other cardiac and vascular implants and grafts	0.650	0.350
S78 Traumatic amputation of hip and thigh	0.648	0.352
S77 Crushing injury of hip and thigh	0.648	0.352
S76 Injury of muscle and tendon at hip and thigh level	0.648	0.352
S75 Injury of blood vessels at hip and thigh level	0.648	0.352
S74 Injury of nerves at hip and thigh level	0.648	0.352
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.648	0.352
S71 Open wound of hip and thigh	0.648	0.352
S70 Superficial injury of hip and thigh	0.648	0.352
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.648	0.352
S90-S99 Injuries to the ankle and foot	0.648	0.352
M49 Spondylopathies in diseases classified elsewhere	0.646	0.354
E80 Disorders of porphyrin and bilirubin metabolism	0.645	0.354
M13.97 Arthritis, unspecified (Ankle and foot)	0.645	0.355
I74 Arterial embolism and thrombosis	0.645	0.355
I78 Diseases of capillaries	0.642	0.358
S06.3 Focal brain injury	0.641	0.359
X60-X84 Intentional self-harm	0.640	0.359
L40.5 Arthropathic psoriasis	0.639	0.361
M05 Seropositive rheumatoid arthritis	0.637	0.363
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.637	0.363
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.637	0.363
V10-V19 Pedal cyclist injured in transport accident	0.636	0.364
M34.9 Systemic sclerosis, unspecified	0.635	0.365
M50.2 Other cervical disk displacement	0.635	0.365
I71.8 Aortic aneurysm of unspecified site, ruptured	0.635	0.365
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.635	0.365
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.635	0.365
I71.3 Abdominal aortic aneurysm, ruptured	0.635	0.365
I71.1 Thoracic aortic aneurysm, ruptured	0.635	0.365
I71.0 Dissection of aorta [any part]	0.635	0.365
V20-V29 Motorcycle rider injured in transport accident	0.634	0.366
E50-E64 Other nutritional deficiencies	0.634	0.366
G30-G32 Other degenerative diseases of the nervous system	0.634	0.366
M51 Other intervertebral disk disorders	0.633	0.366
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.632	0.368
S72.9 Fracture of femur, part unspecified	0.631	0.369
S72.8 Fractures of other parts of femur	0.631	0.369
S72.7 Multiple fractures of femur	0.631	0.369
S72.2 Subtrochanteric fracture	0.631	0.369
L10-L14 Bullous disorders	0.631	0.369
L40.0 Psoriasis vulgaris	0.631	0.369
T79 Certain early complications of trauma, not elsewhere classified	0.630	0.370
M24.9 Joint derangement, unspecified	0.630	0.370
M24.8 Other specific joint derangements, not elsewhere classified	0.630	0.370
M24.7 Protrusio acetabuli	0.630	0.370
M24.6 Ankylosis of joint	0.630	0.370
M24.5 Contracture of joint	0.630	0.370
M24.4 Recurrent dislocation and subluxation of joint	0.630	0.370
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.630	0.370
M24.2 Disorder of ligament	0.630	0.370
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.630	0.370
M47.8 Other spondylosis	0.629	0.371
I12.0 Hypertensive renal disease with renal failure	0.628	0.372
I85 Oesophageal varices	0.628	0.372
M14 Arthropathies in other diseases classified elsewhere	0.627	0.373
M12 Other specific arthropathies	0.627	0.373
M09 Juvenile arthritis in diseases classified elsewhere	0.627	0.373
M08 Juvenile arthritis	0.627	0.373
M79.7 Fibromyalgia	0.627	0.373
I77.6 Arteritis, unspecified	0.626	0.374
L20-L30 Dermatitis and eczema	0.626	0.374
M35.9 Systemic involvement of connective tissue, unspecified	0.625	0.375
M35.8 Other specified systemic involvement of connective tissue	0.625	0.375
M35.6 Relapsing panniculitis [Weber-Christian]	0.625	0.375
M35.5 Multifocal fibrosclerosis	0.625	0.375
M35.4 Diffuse (eosinophilic) fasciitis	0.625	0.375
M35.2 Behcet's disease	0.625	0.375
M35.1 Other overlap syndromes	0.625	0.375
O36 Maternal care for other known or suspected foetal problems	0.624	0.376
S08 Traumatic amputation of part of head	0.624	0.376
S07 Crushing injury of head	0.624	0.376
S04 Injury of cranial nerves	0.624	0.376
S03 Dislocation, sprain and strain of joints and ligaments of head	0.624	0.376
M81.99 Osteoporosis, unspecified (Site unspecified)	0.623	0.377
I22.1 Subsequent myocardial infarction of inferior wall	0.622	0.377
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.621	0.379
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.621	0.379
G55.3 Nerve root and plexus compressions in other dorsopathies	0.619	0.381
M23 Internal derangement of knee	0.619	0.381
M90 Osteopathies in diseases classified elsewhere	0.618	0.381
Z90 Acquired absence of organs, not elsewhere classified	0.618	0.382
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.618	0.382
M79.62 Pain in limb (Upper arm)	0.617	0.383
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.616	0.384
S72.01 Fracture of neck of femur (open)	0.615	0.385
M31.9 Necrotising vasculopathy, unspecified	0.614	0.386
M31.8 Other specified necrotising vasculopathies	0.614	0.386
M31.7 Microscopic polyangiitis	0.614	0.386
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.614	0.386
M31.4 Aortic arch syndrome [Takayasu]	0.614	0.386
M31.3 Wegener's granulomatosis	0.614	0.386
M31.2 Lethal midline granuloma	0.614	0.386
M31.1 Thrombotic microangiopathy	0.614	0.386
M31.0 Hypersensitivity angiitis	0.614	0.386
S01.0 Open wound of scalp	0.614	0.386
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.613	0.387
F10.0 Acute intoxication	0.613	0.387
M25.78 Osteophyte (Other)	0.612	0.388
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.612	0.388
G58 Other mononeuropathies	0.611	0.389
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.610	0.389
F10.3 Withdrawal state	0.610	0.390
I22.0 Subsequent myocardial infarction of anterior wall	0.607	0.393
I72.9 Aneurysm of unspecified site	0.607	0.393
I72.6 Aneurysm and dissection of vertebral artery	0.607	0.393
I72.5 Aneurysm and dissection of other precerebral arteries	0.607	0.393
I72.3 Aneurysm of iliac artery	0.607	0.393
I72.2 Aneurysm of renal artery	0.607	0.393
I72.1 Aneurysm of artery of upper extremity	0.607	0.393
I70.9 Generalised and unspecified atherosclerosis	0.606	0.394
I70.8 Atherosclerosis of other arteries	0.606	0.394
I70.1 Atherosclerosis of renal artery	0.606	0.394
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.606	0.394
Y35-Y36 Legal intervention and operations of war	0.606	0.394
Y10-Y34 Event of undetermined intent	0.606	0.394
Y00-Y09 Assault	0.606	0.394
X85-X99 Assault	0.606	0.394
X58-X59 Accidental exposure to other and unspecified factors	0.606	0.394
X50-X57 Overexertion, travel and privation	0.606	0.394
X40-X49 Accidental poisoning by and exposure to noxious substances	0.606	0.394
X30-X39 Exposure to forces of nature	0.606	0.394
X20-X29 Contact with venomous animals and plants	0.606	0.394
X10-X19 Contact with heat and hot substances	0.606	0.394
X00-X09 Exposure to smoke, fire and flames	0.606	0.394
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.606	0.394
W75-W84 Other accidental threats to breathing	0.606	0.394
W65-W74 Accidental drowning and submersion	0.606	0.394
W50-W64 Exposure to animate mechanical forces	0.606	0.394
V98-V99 Other and unspecified transport accidents	0.606	0.394
V95-V97 Air and space transport accidents	0.606	0.394
V90-V94 Water transport accidents	0.606	0.394
V80-V89 Other land transport accidents	0.606	0.394
V70-V79 Bus occupant injured in transport accident	0.606	0.394
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.606	0.394
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.606	0.394
V40-V49 Car occupant injured in transport accident	0.606	0.394
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.606	0.394
V01-V09 Pedestrian injured in transport accident	0.606	0.394
W20-W49 Exposure to inanimate mechanical forces	0.606	0.394
M84.0 Malunion of fracture	0.603	0.396
T92 Sequelae of injuries of upper limb	0.600	0.399
T17 Foreign body in respiratory tract	0.600	0.400
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.600	0.400
L80 Vitiligo	0.600	0.400
L44 Other papulosquamous disorders	0.599	0.401
L41 Parapsoriasis	0.599	0.401
L45 Papulosquamous disorders in diseases classified elsewhere	0.599	0.401
L42 Pityriasis rosea	0.599	0.401
Z95.0 Presence of cardiac pacemaker	0.599	0.401
E03 Other hypothyroidism	0.599	0.401
F80-F89 Disorders of psychological development	0.599	0.401
Y52 Agents primarily affecting the cardiovascular system	0.598	0.402
F99-F99 Unspecified mental disorder	0.597	0.403
M81.8 Other osteoporosis	0.597	0.403
M81.6 Localised osteoporosis [Lequesne]	0.597	0.403
M81.5 Idiopathic osteoporosis	0.597	0.403
M81.3 Postsurgical malabsorption osteoporosis	0.597	0.403
M81.2 Osteoporosis of disuse	0.597	0.403
M81.1 Postoophorectomy osteoporosis	0.597	0.403
M81.0 Postmenopausal osteoporosis	0.597	0.403
I84.1 Internal haemorrhoids with other complications	0.597	0.403
S72.1 Pertrochanteric fracture	0.597	0.403
F17 Mental and behavioural disorders due to use of tobacco	0.597	0.403
M25.71 Osteophyte (Shoulder region)	0.596	0.404
S06.2 Diffuse brain injury	0.596	0.404
M48.02 Spinal stenosis (Cervical region)	0.595	0.405
S60-S69 Injuries to the wrist and hand	0.595	0.405
M25.79 Osteophyte (Site unspecified)	0.595	0.405
M25.73 Osteophyte (Forearm)	0.595	0.405
M25.70 Osteophyte (Multiple sites)	0.595	0.405
S40-S49 Injuries to the shoulder and upper arm	0.594	0.406
M54.64 Pain in thoracic spine (Thoracic region)	0.594	0.406
G40-G47 Episodic and paroxysmal disorders	0.594	0.406
M79.1 Myalgia	0.594	0.406
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.593	0.407
M11 Other crystal arthropathies	0.592	0.407
G54 Nerve root and plexus disorders	0.592	0.408
W07 Fall involving chair	0.591	0.409
M54.46 Lumbago with sciatica (Lumbar region)	0.591	0.409
M21.3 Wrist or foot drop (acquired)	0.590	0.410
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.589	0.411
M84.9 Disorder of continuity of bone, unspecified	0.588	0.412
M84.8 Other disorders of continuity of bone	0.588	0.412
M84.4 Pathological fracture, not elsewhere classified	0.588	0.412
M84.3 Stress fracture, not elsewhere classified	0.588	0.412
M84.2 Delayed union of fracture	0.588	0.412
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.588	0.412
M50.0 Cervical disk disorder with myelopathy	0.587	0.413
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.587	0.413
T18 Foreign body in alimentary tract	0.586	0.413
G00-G09 Inflammatory diseases of the central nervous system	0.585	0.415
S00.8 Superficial injury of other parts of head	0.585	0.415
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.585	0.415
M88 Paget's disease of bone [osteitis deformans]	0.584	0.416
M79.60 Pain in limb (Multiple sites)	0.584	0.416
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.584	0.416
M47.2 Other spondylosis with radiculopathy	0.584	0.416
M54.29 Cervicalgia-Site unspe	0.584	0.416
M54.28 Cervicalgia-Sacral/sacrococ	0.584	0.416
M54.27 Cervicalgia-Lumbosacral	0.584	0.416
M54.26 Cervicalgia-Lumbar	0.584	0.416
M54.25 Cervicalgia-Thoracolumbar	0.584	0.416
M54.24 Cervicalgia-Thoracic	0.584	0.416
M54.23 Cervicalgia (Cervicothoracic region)	0.584	0.416
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.584	0.416
M54.20 Cervicalgia-Mult site	0.584	0.416
Z85 Personal history of malignant neoplasm	0.582	0.418
M48.5 Collapsed vertebra, not elsewhere classified	0.581	0.419
M86 Osteomyelitis	0.581	0.419
M07.3 Other psoriatic arthropathies	0.580	0.420
I12.9 Hypertensive renal disease without renal failure	0.580	0.420
L40.8 Other psoriasis	0.579	0.421
L40.4 Guttate psoriasis	0.579	0.421
L40.3 Pustulosis palmaris et plantaris	0.579	0.421
L40.2 Acrodermatitis continua	0.579	0.421
L40.1 Generalised pustular psoriasis	0.579	0.421
L85 Other epidermal thickening	0.578	0.422
S80.8 Other superficial injuries of lower leg	0.578	0.422
E07 Other disorders of thyroid	0.577	0.423
M79.8 Other specified soft tissue disorders	0.577	0.423
Z91 Personal history of risk-factors, not elsewhere classified	0.577	0.423
G56.0 Carpal tunnel syndrome	0.575	0.425
I30-I52 Other forms of heart disease	0.575	0.425
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.574	0.426
F70-F79 Mental retardation	0.574	0.426
F60-F69 Disorders of adult personality and behaviour	0.574	0.426
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.574	0.426
M79.69 Pain in limb (Site unspecified)	0.574	0.426
Z98 Other postsurgical states	0.572	0.428
L91 Hypertrophic disorders of skin	0.572	0.428
G90-G99 Other disorders of the nervous system	0.572	0.428
Z90.7 Acquired absence of genital organ(s)	0.572	0.428
L43 Lichen planus	0.572	0.428
W19 Unspecified fall	0.571	0.429
I81 Portal vein thrombosis	0.571	0.429
M21.0 Valgus deformity, not elsewhere classified	0.570	0.430

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations