TreeWAS – Variant ID: rs6258

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
I20-I25 Ischaemic heart diseases	0.999	0.001
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.997	0.003
I25 Chronic ischaemic heart disease	0.994	0.006
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.988	0.012
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.982	0.018
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.981	0.019
R50-R69 General symptoms and signs	0.979	0.021
Chapter VI Diseases of the nervous system	0.979	0.021
I25.9 Chronic ischaemic heart disease, unspecified	0.978	0.022
I20 Angina pectoris	0.978	0.022
R07 Pain in throat and chest	0.971	0.029
G50-G59 Nerve, nerve root and plexus disorders	0.970	0.030
G56 Mononeuropathies of upper limb	0.958	0.042
M70-M79 Other soft tissue disorders	0.956	0.044
I20.0 Unstable angina	0.954	0.046
G56.0 Carpal tunnel syndrome	0.950	0.050
R07.2 Precordial pain	0.940	0.060
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.938	0.062
M79 Other soft tissue disorders, not elsewhere classified	0.937	0.063
Chapter XX External causes of morbidity and mortality	0.930	0.070
Chapter IV Endocrine, nutritional and metabolic diseases	0.923	0.077
I25.8 Other forms of chronic ischaemic heart disease	0.911	0.089
R51 Headache	0.910	0.090
M79.6 Pain in limb	0.906	0.094
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.903	0.097
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.886	0.114
M79.66 Pain in limb (Lower leg)	0.885	0.115
R00 Abnormalities of heart beat	0.882	0.118
R06 Abnormalities of breathing	0.877	0.123
M15-M19 Arthrosis	0.877	0.123
E70-E90 Metabolic disorders	0.874	0.126
Chapter XIV Diseases of the genitourinary system	0.862	0.138
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.856	0.144
T36-T50 Poisoning by drugs, medicaments and biological substances	0.855	0.145
R42 Dizziness and giddiness	0.854	0.146
I70-I79 Diseases of arteries, arterioles and capillaries	0.852	0.148
E78.0 Pure hypercholesterolaemia	0.849	0.151
Chapter II Neoplasms	0.848	0.152
R07.3 Other chest pain	0.842	0.158
R53 Malaise and fatigue	0.834	0.166
I26 Pulmonary embolism	0.833	0.167
M79.8 Other specified soft tissue disorders	0.831	0.169
M65-M68 Disorders of synovium and tendon	0.825	0.175
N30-N39 Other diseases of urinary system	0.823	0.177
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.819	0.181
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.818	0.182
S20-S29 Injuries to the thorax	0.815	0.185
R06.8 Other and unspecified abnormalities of breathing	0.812	0.188
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.804	0.196
R00.2 Palpitations	0.802	0.198
N39 Other disorders of urinary system	0.799	0.201
R41 Other symptoms and signs involving cognitive functions and awareness	0.798	0.202
R52 Pain, not elsewhere classified	0.792	0.208
M20-M25 Other joint disorders	0.792	0.208
R63 Symptoms and signs concerning food and fluid intake	0.790	0.210
R07.4 Chest pain, unspecified	0.785	0.215
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.782	0.218
I20.9 Angina pectoris, unspecified	0.781	0.219
R57 Shock, not elsewhere classified	0.780	0.220
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.779	0.221
S70-S79 Injuries to the hip and thigh	0.778	0.222
S00-S09 Injuries to the head	0.778	0.222
R02 Gangrene, not elsewhere classified	0.777	0.223
I20.1 Angina pectoris with documented spasm	0.776	0.224
N39.3 Stress incontinence	0.770	0.230
I95-I99 Other and unspecified disorders of the circulatory system	0.768	0.232
I25.2 Old myocardial infarction	0.767	0.233
G90-G99 Other disorders of the nervous system	0.764	0.236
I24 Other acute ischaemic heart diseases	0.759	0.241
R07.0 Pain in throat	0.757	0.243
M19 Other arthrosis	0.757	0.243
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.757	0.243
W00-W19 Falls	0.756	0.244
M79.86 Other specified soft tissue disorders (Lower leg)	0.755	0.245
R61 Hyperhidrosis	0.754	0.246
Chapter VIII Diseases of the ear and mastoid process	0.751	0.249
S80-S89 Injuries to the knee and lower leg	0.751	0.249
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.749	0.251
R69 Unknown and unspecified causes of morbidity	0.749	0.251
I25.1 Atherosclerotic heart disease	0.749	0.251
R60 Oedema, not elsewhere classified	0.747	0.253
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.746	0.254
M79.60 Pain in limb (Multiple sites)	0.745	0.255
R68 Other general symptoms and signs	0.743	0.256
M86-M90 Other osteopathies	0.742	0.258
G50 Disorders of trigeminal nerve	0.739	0.261
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.739	0.261
M40-M43 Deforming dorsopathies	0.731	0.269
N60-N64 Disorders of breast	0.729	0.271
E50-E64 Other nutritional deficiencies	0.728	0.272
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.727	0.273
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.725	0.275
M65 Synovitis and tenosynovitis	0.724	0.276
T85 Complications of other internal prosthetic devices, implants and grafts	0.724	0.276
M17 Gonarthrosis [arthrosis of knee]	0.723	0.277
T66-T78 Other and unspecified effects of external causes	0.718	0.282
Chapter XXII Codes for special purposes	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I05-I09 Chronic rheumatic heart diseases	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.716	0.284
S40-S49 Injuries to the shoulder and upper arm	0.716	0.284
R95-R99 Ill-defined and unknown causes of mortality	0.714	0.285
I25.6 Silent myocardial ischaemia	0.713	0.287
I25.5 Ischaemic cardiomyopathy	0.713	0.287
I25.4 Coronary artery aneurysm	0.713	0.287
I25.3 Aneurysm of heart	0.713	0.287
I25.0 Atherosclerotic cardiovascular disease, so described	0.713	0.287
R06.2 Wheezing	0.713	0.287
R47-R49 Symptoms and signs involving speech and voice	0.713	0.287
N39.8 Other specified disorders of urinary system	0.712	0.288
M77 Other enthesopathies	0.709	0.291
M91-M94 Chondropathies	0.709	0.291
M60-M63 Disorders of muscles	0.709	0.291
M00-M03 Infectious arthropathies	0.709	0.291
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.709	0.291
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.708	0.292
V20-V29 Motorcycle rider injured in transport accident	0.707	0.293
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.706	0.294
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.704	0.296
I22 Subsequent myocardial infarction	0.703	0.297
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.703	0.297
T79-T79 Certain early complications of trauma	0.703	0.297
T33-T35 Frostbite	0.703	0.297
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.703	0.297
T26-T28 Burns and corrosions confined to eye and internal organs	0.703	0.297
T20-T25 Burns and corrosions of external body surface, specified by site	0.703	0.297
T15-T19 Effects of foreign body entering through natural orifice	0.703	0.297
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.703	0.297
T00-T07 Injuries involving multiple body regions	0.703	0.297
S90-S99 Injuries to the ankle and foot	0.703	0.297
S10-S19 Injuries to the neck	0.703	0.297
C64-C68 Malignant neoplasms of urinary tract	0.703	0.297
R63.0 Anorexia	0.703	0.297
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.702	0.298
R62 Lack of expected normal physiological development	0.702	0.298
R64 Cachexia	0.702	0.298
R58 Haemorrhage, not elsewhere classified	0.702	0.298
R54 Senility	0.702	0.298
G70-G73 Diseases of myoneural junction and muscle	0.702	0.298
G30-G32 Other degenerative diseases of the nervous system	0.702	0.298
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.702	0.298
G00-G09 Inflammatory diseases of the central nervous system	0.702	0.298
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.701	0.298
Y60-Y69 Misadventures to patients during surgical and medical care	0.701	0.299
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.701	0.299
G51 Facial nerve disorders	0.698	0.302
R41.0 Disorientation, unspecified	0.698	0.302
R07.1 Chest pain on breathing	0.696	0.303
X60-X84 Intentional self-harm	0.696	0.304
G80-G83 Cerebral palsy and other paralytic syndromes	0.696	0.304
G59 Mononeuropathy in diseases classified elsewhere	0.695	0.304
G58 Other mononeuropathies	0.695	0.304
G54 Nerve root and plexus disorders	0.695	0.304
G53 Cranial nerve disorders in diseases classified elsewhere	0.695	0.304
G52 Disorders of other cranial nerves	0.695	0.304
N35 Urethral stricture	0.693	0.307
C34 Malignant neoplasm of bronchus and lung	0.691	0.309
Chapter VII Diseases of the eye and adnexa	0.691	0.309
I30-I52 Other forms of heart disease	0.690	0.310
R50 Fever of unknown origin	0.689	0.311
C51-C58 Malignant neoplasms of female genital organs	0.689	0.311
G56.9 Mononeuropathy of upper limb, unspecified	0.687	0.313
G56.8 Other mononeuropathies of upper limb	0.687	0.313
G56.4 Causalgia	0.687	0.313
G56.3 Lesion of radial nerve	0.687	0.313
G56.1 Other lesions of median nerve	0.687	0.313
M76 Enthesopathies of lower limb, excluding foot	0.686	0.314
M73 Soft tissue disorders in diseases classified elsewhere	0.686	0.314
M71 Other bursopathies	0.686	0.314
M70 Soft tissue disorders related to use, overuse and pressure	0.686	0.314
I78 Diseases of capillaries	0.684	0.316
S22 Fracture of rib(s), sternum and thoracic spine	0.683	0.317
E83 Disorders of mineral metabolism	0.682	0.318
R40 Somnolence, stupor and coma	0.682	0.318
I74 Arterial embolism and thrombosis	0.681	0.318
M05-M14 Inflammatory polyarthropathies	0.680	0.320
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.679	0.321
M19.9 Arthrosis, unspecified	0.678	0.322
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.678	0.322
N99-N99 Other disorders of the genitourinary system	0.677	0.323
I60-I69 Cerebrovascular diseases	0.677	0.323
M80-M85 Disorders of bone density and structure	0.676	0.324
C50-C50 Malignant neoplasm of breast	0.675	0.325
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.674	0.326
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.673	0.327
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.673	0.327
N80-N98 Noninflammatory disorders of female genital tract	0.673	0.327
R46 Symptoms and signs involving appearance and behaviour	0.672	0.328
R45 Symptoms and signs involving emotional state	0.672	0.328
R44 Other symptoms and signs involving general sensations and perceptions	0.672	0.328
R43 Disturbances of smell and taste	0.672	0.328
R56 Convulsions, not elsewhere classified	0.672	0.328
M79.9 Soft tissue disorder, unspecified	0.672	0.328
M79.7 Fibromyalgia	0.672	0.328
M79.5 Residual foreign body in soft tissue	0.672	0.328
M79.4 Hypertrophy of (infrapatellar) fat pad	0.672	0.328
M79.3 Panniculitis, unspecified	0.672	0.328
M79.2 Neuralgia and neuritis, unspecified	0.672	0.328
M79.1 Myalgia	0.672	0.328
S60-S69 Injuries to the wrist and hand	0.668	0.332
M75 Shoulder lesions	0.667	0.333
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.667	0.333
Y35-Y36 Legal intervention and operations of war	0.667	0.333
Y10-Y34 Event of undetermined intent	0.667	0.333
Y00-Y09 Assault	0.667	0.333
X85-X99 Assault	0.667	0.333
X58-X59 Accidental exposure to other and unspecified factors	0.667	0.333
X50-X57 Overexertion, travel and privation	0.667	0.333
X40-X49 Accidental poisoning by and exposure to noxious substances	0.667	0.333
X30-X39 Exposure to forces of nature	0.667	0.333
X20-X29 Contact with venomous animals and plants	0.667	0.333
X10-X19 Contact with heat and hot substances	0.667	0.333
X00-X09 Exposure to smoke, fire and flames	0.667	0.333
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.667	0.333
W75-W84 Other accidental threats to breathing	0.667	0.333
W65-W74 Accidental drowning and submersion	0.667	0.333
W50-W64 Exposure to animate mechanical forces	0.667	0.333
W20-W49 Exposure to inanimate mechanical forces	0.667	0.333
V98-V99 Other and unspecified transport accidents	0.667	0.333
V95-V97 Air and space transport accidents	0.667	0.333
V90-V94 Water transport accidents	0.667	0.333
V80-V89 Other land transport accidents	0.667	0.333
V70-V79 Bus occupant injured in transport accident	0.667	0.333
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.667	0.333
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.667	0.333
V40-V49 Car occupant injured in transport accident	0.667	0.333
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.667	0.333
V10-V19 Pedal cyclist injured in transport accident	0.667	0.333
V01-V09 Pedestrian injured in transport accident	0.667	0.333
G56.2 Lesion of ulnar nerve	0.664	0.336
N30 Cystitis	0.663	0.337
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.663	0.337
G57 Mononeuropathies of lower limb	0.663	0.337
E10-E14 Diabetes mellitus	0.663	0.337
R00.1 Bradycardia, unspecified	0.662	0.337
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.662	0.338
I70 Atherosclerosis	0.662	0.338
E40-E46 Malnutrition	0.661	0.338
E20-E35 Disorders of other endocrine glands	0.661	0.338
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.660	0.340
T84.1 Mechanical complication of internal fixation device of bones of limb	0.660	0.340
G20-G26 Extrapyramidal and movement disorders	0.659	0.341
R52.1 Chronic intractable pain	0.658	0.342
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.658	0.342
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.656	0.344
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.652	0.348
M65.9 Synovitis and tenosynovitis, unspecified	0.650	0.350
M79.69 Pain in limb (Site unspecified)	0.650	0.350
M79.68 Pain in limb (Other)	0.650	0.350
M79.64 Pain in limb (Hand)	0.650	0.350
M79.63 Pain in limb (Forearm)	0.650	0.350
M79.62 Pain in limb (Upper arm)	0.650	0.350
M79.61 Pain in limb (Shoulder region)	0.650	0.350
I27 Other pulmonary heart diseases	0.649	0.350
R59 Enlarged lymph nodes	0.649	0.351
M25 Other joint disorders, not elsewhere classified	0.649	0.351
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.648	0.352
N10-N16 Renal tubulo-interstitial diseases	0.648	0.352
I28 Other diseases of pulmonary vessels	0.647	0.353
G40-G47 Episodic and paroxysmal disorders	0.646	0.354
D37-D48 Neoplasms of uncertain or unknown behaviour	0.644	0.356
E80 Disorders of porphyrin and bilirubin metabolism	0.643	0.356
G35-G37 Demyelinating diseases of the central nervous system	0.640	0.360
H65-H75 Diseases of middle ear and mastoid	0.639	0.361
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.638	0.362
I73 Other peripheral vascular diseases	0.638	0.362
R57.2 Septic shock	0.637	0.363
M23 Internal derangement of knee	0.637	0.363
I20.8 Other forms of angina pectoris	0.636	0.364
Y51 Drugs primarily affecting the autonomic nervous system	0.636	0.364
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.635	0.365
M72 Fibroblastic disorders	0.635	0.365
T88 Other complications of surgical and medical care, not elsewhere classified	0.635	0.365
T87 Complications peculiar to reattachment and amputation	0.635	0.365
T86 Failure and rejection of transplanted organs and tissues	0.635	0.365
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.635	0.365
T80 Complications following infusion, transfusion and therapeutic injection	0.635	0.365
M18 Arthrosis of first carpometacarpal joint	0.633	0.366
S72 Fracture of femur	0.633	0.366
R00.8 Other and unspecified abnormalities of heart beat	0.632	0.368
W19 Unspecified fall	0.632	0.368
M17.0 Primary gonarthrosis, bilateral	0.630	0.370
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.630	0.370
N81 Female genital prolapse	0.630	0.370
R06.7 Sneezing	0.629	0.371
R06.6 Hiccough	0.629	0.371
R06.4 Hyperventilation	0.629	0.371
R06.3 Periodic breathing	0.629	0.371
R06.1 Stridor	0.629	0.371
M79.0 Rheumatism, unspecified	0.628	0.371
M15 Polyarthrosis	0.628	0.371
N61 Inflammatory disorders of breast	0.628	0.372
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.628	0.372
T81 Complications of procedures, not elsewhere classified	0.628	0.372
R00.0 Tachycardia, unspecified	0.628	0.372
G93 Other disorders of brain	0.627	0.373
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.627	0.373
S50-S59 Injuries to the elbow and forearm	0.627	0.373
E88 Other metabolic disorders	0.627	0.373
E85 Amyloidosis	0.627	0.373
E84 Cystic fibrosis	0.627	0.373
E79 Disorders of purine and pyrimidine metabolism	0.627	0.373
E77 Disorders of glycoprotein metabolism	0.627	0.373
E76 Disorders of glycosaminoglycan metabolism	0.627	0.373
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.627	0.373
E74 Other disorders of carbohydrate metabolism	0.627	0.373
E73 Lactose intolerance	0.627	0.373
E72 Other disorders of amino-acid metabolism	0.627	0.373
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.627	0.373
E70 Disorders of aromatic amino-acid metabolism	0.627	0.373
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.627	0.373
M35 Other systemic involvement of connective tissue	0.626	0.374
N00-N08 Glomerular diseases	0.623	0.377
M17.1 Other primary gonarthrosis	0.623	0.377
Chapter V Mental and behavioural disorders	0.623	0.377
C15-C26 Malignant neoplasms of digestive organs	0.621	0.379
M50-M54 Other dorsopathies	0.621	0.379
Chapter XXI Factors influencing health status and contact with health services	0.620	0.380
M79.67 Pain in limb (Ankle and foot)	0.616	0.383
S09 Other and unspecified injuries of head	0.614	0.386
N85 Other noninflammatory disorders of uterus, except cervix	0.614	0.386
E78.9 Disorder of lipoprotein metabolism, unspecified	0.613	0.386
E78.8 Other disorders of lipoprotein metabolism	0.613	0.386
E78.6 Lipoprotein deficiency	0.613	0.386
E78.4 Other hyperlipidaemia	0.613	0.386
E78.3 Hyperchylomicronaemia	0.613	0.386
E78.2 Mixed hyperlipidaemia	0.613	0.386
E78.1 Pure hyperglyceridaemia	0.613	0.386
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.613	0.387
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.613	0.387
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.613	0.387
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.613	0.387
T46 Poisoning by agents primarily affecting the cardiovascular system	0.613	0.387
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.613	0.387
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.613	0.387
T41 Poisoning by anaesthetics and therapeutic gases	0.613	0.387
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.613	0.387
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.613	0.387
T36 Poisoning by systemic antibiotics	0.613	0.387
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.612	0.388
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.611	0.389
I72 Other aneurysm	0.611	0.389
N36 Other disorders of urethra	0.610	0.390
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.608	0.392
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.608	0.392
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.608	0.392
C40-C41 Malignant neoplasms of bone and articular cartilage	0.608	0.392
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.608	0.392
S27 Injury of other and unspecified intrathoracic organs	0.608	0.392
R06.0 Dyspnoea	0.606	0.394
Q50-Q56 Congenital malformations of genital organs	0.604	0.395
M16 Coxarthrosis [arthrosis of hip]	0.603	0.397
I47 Paroxysmal tachycardia	0.602	0.398
I95 Hypotension	0.601	0.399
M45-M49 Spondylopathies	0.600	0.400
N25-N29 Other disorders of kidney and ureter	0.600	0.400
E00-E07 Disorders of thyroid gland	0.599	0.400
N35.9 Urethral stricture, unspecified	0.599	0.401
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.597	0.403
M79.89 Other specified soft tissue disorders (Site unspecified)	0.596	0.404
M79.88 Other specified soft tissue disorders (Other)	0.596	0.404
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.596	0.404
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.596	0.404
M79.84 Other specified soft tissue disorders (Hand)	0.596	0.404
M79.83 Other specified soft tissue disorders (Forearm)	0.596	0.404
M79.82 Other specified soft tissue disorders (Upper arm)	0.596	0.404
M79.81 Other specified soft tissue disorders (Shoulder region)	0.596	0.404
M79.80 Other specified soft tissue disorders (Multiple sites)	0.596	0.404
R61.9 Hyperhidrosis, unspecified	0.592	0.408
Y45.1 Salicylates	0.592	0.408
T42.4 Benzodiazepines	0.592	0.408
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.591	0.408
M66 Spontaneous rupture of synovium and tendon	0.591	0.408
I77 Other disorders of arteries and arterioles	0.590	0.409
N37 Urethral disorders in diseases classified elsewhere	0.590	0.410
N34 Urethritis and urethral syndrome	0.590	0.410
N33 Bladder disorders in diseases classified elsewhere	0.590	0.410
E89.0 Postprocedural hypothyroidism	0.589	0.411
E53 Deficiency of other B group vitamins	0.589	0.411
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.588	0.412
Y59 Other and unspecified vaccines and biological substances	0.587	0.413
Y58 Bacterial vaccines	0.587	0.413
Y57 Other and unspecified drugs and medicaments	0.587	0.413
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.587	0.413
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.587	0.413
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.587	0.413
Y53 Agents primarily affecting the gastro-intestinal system	0.587	0.413
Y52 Agents primarily affecting the cardiovascular system	0.587	0.413
Y50 Central nervous system stimulants, not elsewhere classified	0.587	0.413
Y49 Psychotropic drugs, not elsewhere classified	0.587	0.413
Y48 Anaesthetics and therapeutic gases	0.587	0.413
Y47 Sedatives, hypnotics and antianxiety drugs	0.587	0.413
Y46 Antiepileptics and anti-Parkinsonism drugs	0.587	0.413
Y44 Agents primarily affecting blood constituents	0.587	0.413
Y41 Other systemic anti-infectives and antiparasitics	0.587	0.413
Y40 Systemic antibiotics	0.587	0.413
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.586	0.414
G55.3 Nerve root and plexus compressions in other dorsopathies	0.586	0.414
G55.2 Nerve root and plexus compressions in spondylosis	0.586	0.414
G55.0 Nerve root and plexus compressions in neoplastic disease	0.586	0.414
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.586	0.414
M75.4 Impingement syndrome of shoulder	0.585	0.415
S29 Other and unspecified injuries of thorax	0.584	0.415
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.584	0.415
S26 Injury of heart	0.584	0.415
S25 Injury of blood vessels of thorax	0.584	0.415
S24 Injury of nerves and spinal cord at thorax level	0.584	0.415
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.584	0.415
S21 Open wound of thorax	0.584	0.415
S20 Superficial injury of thorax	0.584	0.415
T84.0 Mechanical complication of internal joint prosthesis	0.583	0.417
M24 Other specific joint derangements	0.581	0.419
R60.0 Localised oedema	0.580	0.420
C34.1 Upper lobe, bronchus or lung	0.580	0.420
I21 Acute myocardial infarction	0.580	0.420
Q20-Q28 Congenital malformations of the circulatory system	0.580	0.420
E65-E68 Obesity and other hyperalimentation	0.580	0.420
S00 Superficial injury of head	0.579	0.421
S82 Fracture of lower leg, including ankle	0.578	0.422
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.577	0.422
C67 Malignant neoplasm of bladder	0.577	0.423
C34.9 Bronchus or lung, unspecified	0.577	0.423
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.577	0.423
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.577	0.423
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.577	0.423
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.577	0.423
T84.3 Mechanical complication of other bone devices, implants and grafts	0.577	0.423
T84.2 Mechanical complication of internal fixation device of other bones	0.577	0.423
R01 Cardiac murmurs and other cardiac sounds	0.576	0.424
R68.8 Other specified general symptoms and signs	0.575	0.425
G50.0 Trigeminal neuralgia	0.573	0.426
N39.9 Disorder of urinary system, unspecified	0.573	0.427
N39.2 Orthostatic proteinuria, unspecified	0.573	0.427
N39.1 Persistent proteinuria, unspecified	0.573	0.427
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.572	0.428
R41.3 Other amnesia	0.572	0.428
R41.2 Retrograde amnesia	0.572	0.428
R41.1 Anterograde amnesia	0.572	0.428
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.571	0.428
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.571	0.429
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.570	0.430
R73 Elevated blood glucose level	0.570	0.430
I24.9 Acute ischaemic heart disease, unspecified	0.569	0.431
I71 Aortic aneurysm and dissection	0.568	0.431
R52.9 Pain, unspecified	0.568	0.432
R52.2 Other chronic pain	0.568	0.432
R52.0 Acute pain	0.568	0.432
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.568	0.432
M34 Systemic sclerosis	0.568	0.432
M33 Dermatopolymyositis	0.568	0.432
M32 Systemic lupus erythematosus	0.568	0.432
M31 Other necrotising vasculopathies	0.568	0.432
M30 Polyarteritis nodosa and related conditions	0.568	0.432
M22 Disorders of patella	0.568	0.432
M21 Other acquired deformities of limbs	0.568	0.432
Y43 Primarily systemic agents	0.567	0.433
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.567	0.433
N60 Benign mammary dysplasia	0.567	0.433
R63.8 Other symptoms and signs concerning food and fluid intake	0.566	0.434
R63.6 Insufficient intake of food and water due to self neglect	0.566	0.434
R63.5 Abnormal weight gain	0.566	0.434
R63.3 Feeding difficulties and mismanagement	0.566	0.434
R63.2 Polyphagia	0.566	0.434
R63.1 Polydipsia	0.566	0.434
Chapter XV Pregnancy, childbirth and the puerperium	0.566	0.434
S30 Superficial injury of abdomen, lower back and pelvis	0.566	0.434
R80 Isolated proteinuria	0.566	0.434
I24.8 Other forms of acute ischaemic heart disease	0.565	0.434
M89 Other disorders of bone	0.565	0.435
I74.5 Embolism and thrombosis of iliac artery	0.565	0.435
I78.1 Naevus, nonneoplastic	0.564	0.436
S01 Open wound of head	0.562	0.437
M13 Other arthritis	0.561	0.439
R57.9 Shock, unspecified	0.559	0.441
R57.8 Other shock	0.559	0.441
R57.1 Hypovolaemic shock	0.559	0.441
R57.0 Cardiogenic shock	0.559	0.441
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.559	0.441
Q80-Q89 Other congenital malformations	0.559	0.441
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.559	0.441
Q60-Q64 Congenital malformations of the urinary system	0.559	0.441
Q38-Q45 Other congenital malformations of the digestive system	0.559	0.441
Q35-Q37 Cleft lip and cleft palate	0.559	0.441
Q30-Q34 Congenital malformations of the respiratory system	0.559	0.441
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.559	0.441
Q00-Q07 Congenital malformations of the nervous system	0.559	0.441
S02 Fracture of skull and facial bones	0.558	0.442
S79 Other and unspecified injuries of hip and thigh	0.558	0.442
S78 Traumatic amputation of hip and thigh	0.558	0.442
S77 Crushing injury of hip and thigh	0.558	0.442
S76 Injury of muscle and tendon at hip and thigh level	0.558	0.442
S75 Injury of blood vessels at hip and thigh level	0.558	0.442
S74 Injury of nerves at hip and thigh level	0.558	0.442
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.558	0.442
S71 Open wound of hip and thigh	0.558	0.442
S70 Superficial injury of hip and thigh	0.558	0.442
S08 Traumatic amputation of part of head	0.558	0.442

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations