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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6534757
log Bayes Factor = 14.7722
Chromosome 4   position 130,956,329  (GRCh37) Explore rs6534757 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
1.000 0.000 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
M15-M19 Arthrosis
0.994 0.006 0.000
M50-M54 Other dorsopathies
0.994 0.006 0.000
M54 Dorsalgia
0.993 0.007 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.991 0.009 0.000
Chapter IX Diseases of the circulatory system
0.991 0.009 0.000
C15-C26 Malignant neoplasms of digestive organs
0.990 0.010 0.000
M54.5 Low back pain
0.989 0.011 0.000
M17 Gonarthrosis [arthrosis of knee]
0.986 0.014 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.984 0.016 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.983 0.017 0.000
M17.1 Other primary gonarthrosis
0.982 0.018 0.000
M79.8 Other specified soft tissue disorders
0.979 0.021 0.000
M79.6 Pain in limb
0.975 0.025 0.000
C64-C68 Malignant neoplasms of urinary tract
0.970 0.030 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.954 0.046 0.000
C67 Malignant neoplasm of bladder
0.953 0.047 0.000
M79.66 Pain in limb (Lower leg)
0.948 0.052 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.947 0.053 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.946 0.054 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.944 0.056 0.000
C79 Secondary malignant neoplasm of other sites
0.943 0.057 0.000
M75 Shoulder lesions
0.939 0.061 0.000
I71 Aortic aneurysm and dissection
0.938 0.062 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.935 0.065 0.000
M45-M49 Spondylopathies
0.935 0.065 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.932 0.068 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.931 0.069 0.000
O60-O75 Complications of labour and delivery
0.929 0.071 0.000
I60-I69 Cerebrovascular diseases
0.927 0.073 0.000
C18 Malignant neoplasm of colon
0.922 0.078 0.000
M54.57 Low back pain (Lumbosacral region)
0.920 0.080 0.000
Chapter X Diseases of the respiratory system
0.919 0.081 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.917 0.083 0.000
S70-S79 Injuries to the hip and thigh
0.912 0.088 0.000
Chapter XXI Factors influencing health status and contact with health services
0.909 0.091 0.000
M54.59 Low back pain (Site unspecified)
0.909 0.091 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.907 0.093 0.000
M54.56 Low back pain (Lumbar region)
0.900 0.100 0.000
M18 Arthrosis of first carpometacarpal joint
0.900 0.100 0.000
Chapter XX External causes of morbidity and mortality
0.897 0.103 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.894 0.106 0.000
S00-S09 Injuries to the head
0.893 0.107 0.000
Chapter I Certain infectious and parasitic diseases
0.892 0.108 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.891 0.109 0.000
J30-J39 Other diseases of upper respiratory tract
0.890 0.110 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.889 0.111 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.889 0.111 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.886 0.114 0.000
C15 Malignant neoplasm of oesophagus
0.884 0.116 0.000
L03 Cellulitis
0.883 0.117 0.000
I30-I52 Other forms of heart disease
0.878 0.122 0.000
C67.9 Bladder, unspecified
0.873 0.127 0.000
C20 Malignant neoplasm of rectum
0.873 0.127 0.000
Z92 Personal history of medical treatment
0.868 0.132 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.865 0.135 0.000
M75.4 Impingement syndrome of shoulder
0.865 0.135 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.864 0.136 0.000
I65.2 Occlusion and stenosis of carotid artery
0.862 0.138 0.000
Chapter VI Diseases of the nervous system
0.858 0.142 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.857 0.143 0.000
D70 Agranulocytosis
0.857 0.143 0.000
C77.0 Lymph nodes of head, face and neck
0.852 0.148 0.000
C67.2 Lateral wall of bladder
0.849 0.151 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.849 0.151 0.000
L03.1 Cellulitis of other parts of limb
0.847 0.153 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.843 0.157 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.843 0.157 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.840 0.160 0.000
I78 Diseases of capillaries
0.838 0.162 0.000
Z88.6 Personal history of allergy to analgesic agent
0.838 0.162 0.000
S72 Fracture of femur
0.836 0.164 0.000
I77 Other disorders of arteries and arterioles
0.835 0.165 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.835 0.165 0.000
M54.2 Cervicalgia
0.835 0.165 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.833 0.167 0.000
M79.7 Fibromyalgia
0.833 0.167 0.000
M54.4 Lumbago with sciatica
0.831 0.169 0.000
E00-E07 Disorders of thyroid gland
0.828 0.172 0.000
C79.6 Secondary malignant neoplasm of ovary
0.827 0.173 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.825 0.175 0.000
Chapter VIII Diseases of the ear and mastoid process
0.825 0.175 0.000
T93 Sequelae of injuries of lower limb
0.823 0.176 0.000
S09 Other and unspecified injuries of head
0.821 0.179 0.000
M54.50 Low back pain (Multiple sites in spine)
0.821 0.179 0.000
A00-A09 Intestinal infectious diseases
0.821 0.179 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.819 0.181 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.819 0.181 0.000
I74 Arterial embolism and thrombosis
0.819 0.181 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.816 0.184 0.000
J32 Chronic sinusitis
0.815 0.185 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.813 0.187 0.000
M48 Other spondylopathies
0.812 0.188 0.000
T92 Sequelae of injuries of upper limb
0.811 0.189 0.000
T66-T78 Other and unspecified effects of external causes
0.811 0.189 0.000
C66 Malignant neoplasm of ureter
0.810 0.190 0.000
M47 Spondylosis
0.809 0.191 0.000
B95-B98 Bacterial, viral and other infectious agents
0.809 0.191 0.000
S40-S49 Injuries to the shoulder and upper arm
0.808 0.192 0.000
T79-T79 Certain early complications of trauma
0.807 0.193 0.000
M79.2 Neuralgia and neuritis, unspecified
0.807 0.193 0.000
Z86 Personal history of certain other diseases
0.804 0.196 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.802 0.198 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.802 0.198 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.801 0.199 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.800 0.200 0.000
M77 Other enthesopathies
0.800 0.200 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.800 0.200 0.000
S10-S19 Injuries to the neck
0.799 0.201 0.000
M54.9 Dorsalgia, unspecified
0.798 0.202 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.797 0.203 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.796 0.204 0.000
C67.4 Posterior wall of bladder
0.796 0.204 0.000
A04 Other bacterial intestinal infections
0.793 0.207 0.000
S20-S29 Injuries to the thorax
0.792 0.208 0.000
M17.0 Primary gonarthrosis, bilateral
0.790 0.210 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.788 0.212 0.000
C15.9 Oesophagus, unspecified
0.788 0.212 0.000
C16 Malignant neoplasm of stomach
0.787 0.213 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.787 0.213 0.000
O63 Long labour
0.787 0.213 0.000
D50-D53 Nutritional anaemias
0.785 0.215 0.000
M16 Coxarthrosis [arthrosis of hip]
0.784 0.216 0.000
M79.69 Pain in limb (Site unspecified)
0.784 0.216 0.000
M75.1 Rotator cuff syndrome
0.784 0.216 0.000
S90-S99 Injuries to the ankle and foot
0.783 0.216 0.000
E20-E35 Disorders of other endocrine glands
0.781 0.219 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.780 0.220 0.000
C80 Malignant neoplasm without specification of site
0.778 0.222 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.777 0.222 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.776 0.224 0.000
J95-J99 Other diseases of the respiratory system
0.774 0.226 0.000
A04.8 Other specified bacterial intestinal infections
0.774 0.226 0.000
D60-D64 Aplastic and other anaemias
0.772 0.228 0.000
I72 Other aneurysm
0.772 0.228 0.000
C67.3 Anterior wall of bladder
0.771 0.229 0.000
M91-M94 Chondropathies
0.771 0.229 0.000
E65-E68 Obesity and other hyperalimentation
0.771 0.229 0.000
M65-M68 Disorders of synovium and tendon
0.770 0.230 0.000
S09.9 Unspecified injury of head
0.770 0.230 0.000
M86-M90 Other osteopathies
0.769 0.231 0.000
M60-M63 Disorders of muscles
0.767 0.233 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.765 0.235 0.000
J90-J94 Other diseases of pleura
0.764 0.236 0.000
Z86.7 Personal history of diseases of the circulatory system
0.763 0.237 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.761 0.239 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.761 0.239 0.000
M76 Enthesopathies of lower limb, excluding foot
0.760 0.240 0.000
E70-E90 Metabolic disorders
0.760 0.240 0.000
I31 Other diseases of pericardium
0.759 0.241 0.000
J30 Vasomotor and allergic rhinitis
0.759 0.241 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.758 0.241 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.758 0.242 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.758 0.242 0.000
I50 Heart failure
0.758 0.242 0.000
O70 Perineal laceration during delivery
0.757 0.243 0.000
Z85 Personal history of malignant neoplasm
0.757 0.243 0.000
M05-M14 Inflammatory polyarthropathies
0.757 0.243 0.000
C21 Malignant neoplasm of anus and anal canal
0.756 0.244 0.000
M75.0 Adhesive capsulitis of shoulder
0.756 0.244 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.755 0.245 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.754 0.246 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.753 0.247 0.000
J32.9 Chronic sinusitis, unspecified
0.752 0.248 0.000
C18.2 Ascending colon
0.752 0.248 0.000
D48.5 Skin
0.750 0.250 0.000
E50-E64 Other nutritional deficiencies
0.749 0.250 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.749 0.251 0.000
H60-H62 Diseases of external ear
0.748 0.252 0.000
M80-M85 Disorders of bone density and structure
0.748 0.252 0.000
O48 Prolonged pregnancy
0.748 0.252 0.000
S06 Intracranial injury
0.747 0.253 0.000
M79.62 Pain in limb (Upper arm)
0.746 0.253 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.746 0.254 0.000
M47.8 Other spondylosis
0.746 0.254 0.000
M54.6 Pain in thoracic spine
0.746 0.254 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.746 0.254 0.000
O66 Other obstructed labour
0.744 0.256 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.744 0.256 0.000
M17.3 Other posttraumatic gonarthrosis
0.743 0.257 0.000
Chapter XXII Codes for special purposes
0.743 0.257 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.743 0.257 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.740 0.260 0.000
O85-O92 Complications predominantly related to the puerperium
0.739 0.261 0.000
C77.5 Intrapelvic lymph nodes
0.739 0.261 0.000
E04 Other non-toxic goitre
0.736 0.264 0.000
C18.9 Colon, unspecified
0.736 0.264 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.736 0.264 0.000
S72.0 Fracture of neck of femur
0.736 0.264 0.000
O42 Premature rupture of membranes
0.735 0.264 0.000
C18.7 Sigmoid colon
0.735 0.265 0.000
I73 Other peripheral vascular diseases
0.735 0.265 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.735 0.265 0.000
I78.1 Naevus, nonneoplastic
0.735 0.265 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.734 0.266 0.000
Z94 Transplanted organ and tissue status
0.734 0.266 0.000
T98 Sequelae of other and unspecified effects of external causes
0.733 0.267 0.000
G90-G99 Other disorders of the nervous system
0.733 0.267 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.733 0.267 0.000
C77.9 Lymph node, unspecified
0.731 0.269 0.000
C34 Malignant neoplasm of bronchus and lung
0.730 0.270 0.000
S60-S69 Injuries to the wrist and hand
0.730 0.270 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.730 0.270 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.729 0.271 0.000
M54.1 Radiculopathy
0.728 0.272 0.000
C18.5 Splenic flexure
0.728 0.272 0.000
L03.8 Cellulitis of other sites
0.727 0.273 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.726 0.273 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.722 0.278 0.000
M54.22 Cervicalgia (Cervical region)
0.721 0.279 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.721 0.279 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.721 0.279 0.000
O41 Other disorders of amniotic fluid and membranes
0.720 0.280 0.000
M46 Other inflammatory spondylopathies
0.720 0.280 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.719 0.281 0.000
M75.9 Shoulder lesion, unspecified
0.719 0.281 0.000
O43 Placental disorders
0.718 0.282 0.000
T91 Sequelae of injuries of neck and trunk
0.718 0.282 0.000
D46 Myelodysplastic syndromes
0.718 0.282 0.000
Z98 Other postsurgical states
0.718 0.282 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.717 0.283 0.000
M71 Other bursopathies
0.717 0.283 0.000
M79.9 Soft tissue disorder, unspecified
0.716 0.284 0.000
M79.5 Residual foreign body in soft tissue
0.716 0.284 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.716 0.284 0.000
M79.3 Panniculitis, unspecified
0.716 0.284 0.000
M79.1 Myalgia
0.716 0.284 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.716 0.284 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
T92.1 Sequelae of fracture of arm
0.714 0.286 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.714 0.286 0.000
M79.79 Fibromyalgia (Site unspecified)
0.714 0.286 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.714 0.286 0.000
M40-M43 Deforming dorsopathies
0.713 0.287 0.000
M15 Polyarthrosis
0.713 0.287 0.000
M54.8 Other dorsalgia
0.712 0.288 0.000
M54.0 Panniculitis affecting regions of neck and back
0.712 0.288 0.000
T90 Sequelae of injuries of head
0.711 0.289 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.711 0.289 0.000
L03.9 Cellulitis, unspecified
0.711 0.289 0.000
O40 Polyhydramnios
0.711 0.289 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.710 0.290 0.000
I00-I02 Acute rheumatic fever
0.710 0.290 0.000
L50-L54 Urticaria and erythema
0.710 0.290 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.710 0.290 0.000
C17 Malignant neoplasm of small intestine
0.710 0.290 0.000
C23 Malignant neoplasm of gallbladder
0.710 0.290 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.710 0.290 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.710 0.290 0.000
L40-L45 Papulosquamous disorders
0.709 0.290 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.709 0.290 0.000
M54.55 Low back pain (Thoracolumbar region)
0.709 0.291 0.000
M54.54 Low back pain-Thoracic
0.709 0.291 0.000
M54.53 Low back pain-Cervicothoracic
0.709 0.291 0.000
M54.52 Low back pain-Cervical
0.709 0.291 0.000
M54.51 Low back pain-Occipit-atl-axl
0.709 0.291 0.000
I60 Subarachnoid haemorrhage
0.709 0.291 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.709 0.291 0.000
V10-V19 Pedal cyclist injured in transport accident
0.707 0.293 0.000
M17.5 Other secondary gonarthrosis
0.707 0.293 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.707 0.293 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.707 0.293 0.000
S30.1 Contusion of abdominal wall
0.707 0.293 0.000
C79.2 Secondary malignant neoplasm of skin
0.706 0.293 0.000
M53 Other dorsopathies, not elsewhere classified
0.706 0.294 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.705 0.295 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.704 0.296 0.000
H61 Other disorders of external ear
0.704 0.296 0.000
M79.0 Rheumatism, unspecified
0.704 0.296 0.000
E83 Disorders of mineral metabolism
0.703 0.297 0.000
I61 Intracerebral haemorrhage
0.703 0.297 0.000
M79.64 Pain in limb (Hand)
0.703 0.297 0.000
M79.88 Other specified soft tissue disorders (Other)
0.702 0.298 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.702 0.298 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.702 0.298 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.702 0.298 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.702 0.298 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.702 0.298 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.701 0.299 0.000
I36 Nonrheumatic tricuspid valve disorders
0.700 0.300 0.000
M79.68 Pain in limb (Other)
0.699 0.301 0.000
M79.63 Pain in limb (Forearm)
0.699 0.301 0.000
M79.61 Pain in limb (Shoulder region)
0.699 0.301 0.000
C15.4 Middle third of oesophagus
0.698 0.302 0.000
I63 Cerebral infarction
0.697 0.302 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.697 0.303 0.000
D75 Other diseases of blood and blood-forming organs
0.696 0.304 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.696 0.304 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.695 0.305 0.000
C65 Malignant neoplasm of renal pelvis
0.695 0.305 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.694 0.306 0.000
C18.0 Caecum
0.694 0.306 0.000
C18.4 Transverse colon
0.694 0.306 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.694 0.306 0.000
L03.0 Cellulitis of finger and toe
0.692 0.307 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.692 0.308 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.692 0.308 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.691 0.309 0.000
S70 Superficial injury of hip and thigh
0.690 0.310 0.000
I05-I09 Chronic rheumatic heart diseases
0.690 0.310 0.000
C78.7 Secondary malignant neoplasm of liver
0.689 0.311 0.000
J33 Nasal polyp
0.689 0.311 0.000
M79.60 Pain in limb (Multiple sites)
0.688 0.311 0.000
I31.3 Pericardial effusion (noninflammatory)
0.688 0.312 0.000
I44 Atrioventricular and left bundle-branch block
0.685 0.315 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.685 0.315 0.000
T93.2 Sequelae of other fractures of lower limb
0.684 0.316 0.000
I70 Atherosclerosis
0.684 0.316 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.684 0.316 0.000
C67.8 Overlapping lesion of bladder
0.683 0.317 0.000
C67.7 Urachus
0.683 0.317 0.000
C67.6 Ureteric orifice
0.683 0.317 0.000
C67.5 Bladder neck
0.683 0.317 0.000
C67.1 Dome of bladder
0.683 0.317 0.000
C67.0 Trigone of bladder
0.683 0.317 0.000
M16.1 Other primary coxarthrosis
0.683 0.317 0.000
Y86 Sequelae of other accidents
0.682 0.318 0.000
M79.67 Pain in limb (Ankle and foot)
0.681 0.319 0.000
L08 Other local infections of skin and subcutaneous tissue
0.681 0.319 0.000
C77.8 Lymph nodes of multiple regions
0.681 0.319 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.681 0.319 0.000
Z83 Family history of other specific disorders
0.680 0.320 0.000
X60-X84 Intentional self-harm
0.680 0.320 0.000
D55-D59 Haemolytic anaemias
0.679 0.321 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.679 0.321 0.000
I37 Pulmonary valve disorders
0.679 0.321 0.000
M54.3 Sciatica
0.678 0.322 0.000
T95 Sequelae of burns, corrosions and frostbite
0.678 0.322 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.678 0.322 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.678 0.322 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.678 0.322 0.000
I50.0 Congestive heart failure
0.678 0.322 0.000
M48.0 Spinal stenosis
0.678 0.322 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.678 0.322 0.000
M45 Ankylosing spondylitis
0.678 0.322 0.000
M05 Seropositive rheumatoid arthritis
0.677 0.323 0.000
T78 Adverse effects, not elsewhere classified
0.677 0.323 0.000
I33 Acute and subacute endocarditis
0.677 0.323 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.677 0.323 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.677 0.323 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.677 0.323 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.677 0.323 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.676 0.324 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.676 0.324 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.676 0.324 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.676 0.324 0.000
I77.6 Arteritis, unspecified
0.676 0.324 0.000
O80-O84 Delivery
0.675 0.324 0.000
S79 Other and unspecified injuries of hip and thigh
0.675 0.325 0.000
O47 False labour
0.674 0.326 0.000
Y85 Sequelae of transport accidents
0.673 0.326 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.673 0.327 0.000
M75.8 Other shoulder lesions
0.673 0.327 0.000
M75.2 Bicipital tendinitis
0.673 0.327 0.000
D61 Other aplastic anaemias
0.673 0.327 0.000
S42 Fracture of shoulder and upper arm
0.673 0.327 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.673 0.327 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.672 0.328 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.672 0.328 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.672 0.328 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.672 0.328 0.000
I71.0 Dissection of aorta [any part]
0.672 0.328 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.671 0.329 0.000
I38 Endocarditis, valve unspecified
0.671 0.329 0.000
O45 Premature separation of placenta [abruptio placentae]
0.671 0.329 0.000
O44 Placenta praevia
0.671 0.329 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.671 0.329 0.000
O33 Maternal care for known or suspected disproportion
0.671 0.329 0.000
O31 Complications specific to multiple gestation
0.671 0.329 0.000
M49 Spondylopathies in diseases classified elsewhere
0.670 0.329 0.000
G81 Hemiplegia
0.670 0.330 0.000
C16.0 Cardia
0.670 0.330 0.000
E06 Thyroiditis
0.670 0.330 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.670 0.330 0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)
0.669 0.331 0.000
I51 Complications and ill-defined descriptions of heart disease
0.669 0.331 0.000
J32.8 Other chronic sinusitis
0.669 0.331 0.000
L10-L14 Bullous disorders
0.667 0.333 0.000
J39 Other diseases of upper respiratory tract
0.667 0.333 0.000
C18.6 Descending colon
0.667 0.333 0.000
S80-S89 Injuries to the knee and lower leg
0.666 0.334 0.000
A80-A89 Viral infections of the central nervous system
0.666 0.334 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.666 0.334 0.000
O74 Complications of anaesthesia during labour and delivery
0.666 0.334 0.000
O73 Retained placenta and membranes, without haemorrhage
0.666 0.334 0.000
O71 Other obstetric trauma
0.666 0.334 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.666 0.334 0.000
O61 Failed induction of labour
0.666 0.334 0.000
O60 Preterm delivery
0.666 0.334 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.665 0.335 0.000
E40-E46 Malnutrition
0.665 0.335 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.664 0.335 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.664 0.335 0.000
S72.00 Fracture of neck of femur (closed)
0.664 0.336 0.000
L05 Pilonidal cyst
0.663 0.337 0.000
C18.8 Overlapping lesion of colon
0.661 0.339 0.000
C18.3 Hepatic flexure
0.661 0.339 0.000
C18.1 Appendix
0.661 0.339 0.000
G70-G73 Diseases of myoneural junction and muscle
0.661 0.339 0.000
S72.4 Fracture of lower end of femur
0.660 0.340 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.660 0.340 0.000
D38.1 Trachea, bronchus and lung
0.658 0.342 0.000
J38.7 Other diseases of larynx
0.658 0.342 0.000
L04 Acute lymphadenitis
0.658 0.342 0.000
L01 Impetigo
0.658 0.342 0.000
L00 Staphylococcal scalded skin syndrome
0.658 0.342 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.657 0.343 0.000
C91 Lymphoid leukaemia
0.656 0.344 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.656 0.344 0.000
E66 Obesity
0.656 0.344 0.000
W20-W49 Exposure to inanimate mechanical forces
0.655 0.345 0.000
S78 Traumatic amputation of hip and thigh
0.654 0.346 0.000
S77 Crushing injury of hip and thigh
0.654 0.346 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.654 0.346 0.000
S75 Injury of blood vessels at hip and thigh level
0.654 0.346 0.000
S74 Injury of nerves at hip and thigh level
0.654 0.346 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.654 0.346 0.000
S71 Open wound of hip and thigh
0.654 0.346 0.000
D51 Vitamin B12 deficiency anaemia
0.654 0.346 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.654 0.346 0.000
J30.1 Allergic rhinitis due to pollen
0.654 0.346 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.653 0.347 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.653 0.347 0.000
O63.0 Prolonged first stage (of labour)
0.652 0.348 0.000
I62 Other nontraumatic intracranial haemorrhage
0.652 0.348 0.000
J38.3 Other diseases of vocal cords
0.652 0.348 0.000
Z89 Acquired absence of limb
0.651 0.349 0.000
M72 Fibroblastic disorders
0.650 0.349 0.000
C77.4 Inguinal and lower limb lymph nodes
0.650 0.350 0.000
I34 Nonrheumatic mitral valve disorders
0.650 0.350 0.000
M16.7 Other secondary coxarthrosis
0.649 0.351 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.648 0.352 0.000
C92 Myeloid leukaemia
0.647 0.353 0.000
M47.86 Other spondylosis (Lumbar region)
0.647 0.353 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.646 0.354 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.646 0.354 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.645 0.355 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.645 0.355 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.645 0.355 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.645 0.355 0.000
M75.5 Bursitis of shoulder
0.645 0.355 0.000
D80-D89 Certain disorders involving the immune mechanism
0.644 0.356 0.000
J91 Pleural effusion in conditions classified elsewhere
0.644 0.356 0.000
I50.1 Left ventricular failure
0.644 0.356 0.000
G57 Mononeuropathies of lower limb
0.644 0.356 0.000
C77.1 Intrathoracic lymph nodes
0.644 0.356 0.000
I35 Nonrheumatic aortic valve disorders
0.644 0.356 0.000
C22.1 Intrahepatic bile duct carcinoma
0.643 0.357 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.643 0.357 0.000
Y35-Y36 Legal intervention and operations of war
0.643 0.357 0.000
Y10-Y34 Event of undetermined intent
0.643 0.357 0.000
Y00-Y09 Assault
0.643 0.357 0.000
X85-X99 Assault
0.643 0.357 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.643 0.357 0.000
X50-X57 Overexertion, travel and privation
0.643 0.357 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.643 0.357 0.000
X30-X39 Exposure to forces of nature
0.643 0.357 0.000
X20-X29 Contact with venomous animals and plants
0.643 0.357 0.000
X10-X19 Contact with heat and hot substances
0.643 0.357 0.000
X00-X09 Exposure to smoke, fire and flames
0.643 0.357 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.643 0.357 0.000
W75-W84 Other accidental threats to breathing
0.643 0.357 0.000
W65-W74 Accidental drowning and submersion
0.643 0.357 0.000
W50-W64 Exposure to animate mechanical forces
0.643 0.357 0.000
V98-V99 Other and unspecified transport accidents
0.643 0.357 0.000
V95-V97 Air and space transport accidents
0.643 0.357 0.000
V90-V94 Water transport accidents
0.643 0.357 0.000
V80-V89 Other land transport accidents
0.643 0.357 0.000
V70-V79 Bus occupant injured in transport accident
0.643 0.357 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.643 0.357 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.643 0.357 0.000
V40-V49 Car occupant injured in transport accident
0.643 0.357 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.643 0.357 0.000
V01-V09 Pedestrian injured in transport accident
0.643 0.357 0.000
J09-J18 Influenza and pneumonia
0.641 0.359 0.000
J38.4 Oedema of larynx
0.641 0.359 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.641 0.359 0.000
D74 Methaemoglobinaemia
0.641 0.359 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.641 0.359 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.641 0.359 0.000
S72.3 Fracture of shaft of femur
0.640 0.359 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.640 0.360 0.000
S08 Traumatic amputation of part of head
0.640 0.360 0.000
S07 Crushing injury of head
0.640 0.360 0.000
S05 Injury of eye and orbit
0.640 0.360 0.000
S04 Injury of cranial nerves
0.640 0.360 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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