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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6679342
log Bayes Factor = 13.0009
Chromosome 1   position 81,656,935  (GRCh37) Explore rs6679342 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
C15-C26 Malignant neoplasms of digestive organs
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
Chapter VII Diseases of the eye and adnexa
0.994 0.006 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.992 0.008 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.992 0.008 0.000
F30-F39 Mood [affective] disorders
0.991 0.009 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.990 0.010 0.000
H30-H36 Disorders of choroid and retina
0.985 0.015 0.000
H35 Other retinal disorders
0.980 0.020 0.000
C78.0 Secondary malignant neoplasm of lung
0.974 0.026 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.972 0.028 0.000
Chapter VI Diseases of the nervous system
0.969 0.031 0.000
D00-D09 In situ neoplasms
0.966 0.034 0.000
C79 Secondary malignant neoplasm of other sites
0.961 0.039 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.960 0.040 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.959 0.041 0.000
C64-C68 Malignant neoplasms of urinary tract
0.954 0.046 0.000
Chapter VIII Diseases of the ear and mastoid process
0.949 0.051 0.000
H35.3 Degeneration of macula and posterior pole
0.944 0.056 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.944 0.056 0.000
C77.1 Intrathoracic lymph nodes
0.943 0.057 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.941 0.059 0.000
C16 Malignant neoplasm of stomach
0.939 0.061 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.937 0.063 0.000
G90-G99 Other disorders of the nervous system
0.935 0.065 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.928 0.072 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.924 0.076 0.000
C78.2 Secondary malignant neoplasm of pleura
0.924 0.076 0.000
E20-E35 Disorders of other endocrine glands
0.923 0.077 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.922 0.078 0.000
F31 Bipolar affective disorder
0.918 0.082 0.000
F33 Recurrent depressive disorder
0.914 0.086 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.914 0.086 0.000
H65-H75 Diseases of middle ear and mastoid
0.912 0.088 0.000
H50 Other strabismus
0.912 0.088 0.000
C15 Malignant neoplasm of oesophagus
0.910 0.090 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.910 0.090 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.901 0.099 0.000
H50.1 Divergent concomitant strabismus
0.901 0.099 0.000
W20-W49 Exposure to inanimate mechanical forces
0.897 0.103 0.000
C78.7 Secondary malignant neoplasm of liver
0.897 0.103 0.000
C16.0 Cardia
0.895 0.105 0.000
H36 Retinal disorders in diseases classified elsewhere
0.893 0.107 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.892 0.108 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.888 0.112 0.000
F29 Unspecified nonorganic psychosis
0.887 0.113 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.885 0.115 0.000
S90-S99 Injuries to the ankle and foot
0.881 0.119 0.000
S40-S49 Injuries to the shoulder and upper arm
0.881 0.119 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.881 0.119 0.000
S20-S29 Injuries to the thorax
0.880 0.120 0.000
Y95 Nosocomial condition
0.879 0.121 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.876 0.124 0.000
H80-H83 Diseases of inner ear
0.874 0.126 0.000
F32 Depressive episode
0.873 0.127 0.000
S70-S79 Injuries to the hip and thigh
0.872 0.128 0.000
H71 Cholesteatoma of middle ear
0.870 0.130 0.000
F60-F69 Disorders of adult personality and behaviour
0.861 0.139 0.000
H35.0 Background retinopathy and retinal vascular changes
0.861 0.139 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.860 0.140 0.000
H40-H42 Glaucoma
0.858 0.142 0.000
C71 Malignant neoplasm of brain
0.855 0.145 0.000
T66-T78 Other and unspecified effects of external causes
0.855 0.145 0.000
W25 Contact with sharp glass
0.853 0.147 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.852 0.148 0.000
E10-E14 Diabetes mellitus
0.849 0.151 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.848 0.152 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.846 0.154 0.000
W00-W19 Falls
0.843 0.157 0.000
C67 Malignant neoplasm of bladder
0.843 0.157 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.839 0.161 0.000
Q80-Q89 Other congenital malformations
0.838 0.162 0.000
S50-S59 Injuries to the elbow and forearm
0.837 0.163 0.000
T42.4 Benzodiazepines
0.837 0.163 0.000
H35.8 Other specified retinal disorders
0.837 0.163 0.000
V40-V49 Car occupant injured in transport accident
0.837 0.163 0.000
S32 Fracture of lumbar spine and pelvis
0.834 0.166 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.830 0.169 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.830 0.170 0.000
E27 Other disorders of adrenal gland
0.830 0.170 0.000
E22 Hyperfunction of pituitary gland
0.829 0.171 0.000
D05 Carcinoma in situ of breast
0.829 0.171 0.000
H74 Other disorders of middle ear and mastoid
0.828 0.172 0.000
H36.0 Diabetic retinopathy
0.826 0.174 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.826 0.174 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.825 0.175 0.000
Q50-Q56 Congenital malformations of genital organs
0.823 0.177 0.000
S00-S09 Injuries to the head
0.823 0.177 0.000
W25.9 Unspecified place
0.822 0.178 0.000
F32.0 Mild depressive episode
0.818 0.182 0.000
F99-F99 Unspecified mental disorder
0.817 0.183 0.000
C34 Malignant neoplasm of bronchus and lung
0.816 0.184 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.809 0.190 0.000
G90 Disorders of autonomic nervous system
0.809 0.191 0.000
C23 Malignant neoplasm of gallbladder
0.807 0.193 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.806 0.194 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.805 0.195 0.000
F33.9 Recurrent depressive disorder, unspecified
0.803 0.197 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.803 0.197 0.000
C77.5 Intrapelvic lymph nodes
0.801 0.199 0.000
V10-V19 Pedal cyclist injured in transport accident
0.800 0.200 0.000
D03 Melanoma in situ
0.797 0.203 0.000
D09 Carcinoma in situ of other and unspecified sites
0.795 0.205 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.795 0.205 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.794 0.206 0.000
C15.5 Lower third of oesophagus
0.794 0.206 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.793 0.207 0.000
F30 Manic episode
0.791 0.209 0.000
D06 Carcinoma in situ of cervix uteri
0.791 0.209 0.000
H35.2 Other proliferative retinopathy
0.787 0.213 0.000
H35.4 Peripheral retinal degeneration
0.786 0.214 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.785 0.215 0.000
G93 Other disorders of brain
0.784 0.216 0.000
D05.1 Intraductal carcinoma in situ
0.784 0.216 0.000
S32.0 Fracture of lumbar vertebra
0.784 0.216 0.000
S22.3 Fracture of rib
0.781 0.219 0.000
G57 Mononeuropathies of lower limb
0.781 0.219 0.000
E65-E68 Obesity and other hyperalimentation
0.780 0.220 0.000
G91 Hydrocephalus
0.779 0.221 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.779 0.221 0.000
H83 Other diseases of inner ear
0.774 0.226 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.773 0.227 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.771 0.229 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.769 0.231 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.767 0.233 0.000
C15.9 Oesophagus, unspecified
0.767 0.233 0.000
C71.3 Parietal lobe
0.766 0.234 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.765 0.235 0.000
H35.6 Retinal haemorrhage
0.763 0.237 0.000
F60 Specific personality disorders
0.763 0.237 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.762 0.238 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.761 0.238 0.000
C34.9 Bronchus or lung, unspecified
0.761 0.239 0.000
H40 Glaucoma
0.761 0.239 0.000
C77.9 Lymph node, unspecified
0.761 0.239 0.000
F80-F89 Disorders of psychological development
0.760 0.240 0.000
F41 Other anxiety disorders
0.760 0.240 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.758 0.242 0.000
H53-H54 Visual disturbances and blindness
0.758 0.242 0.000
G51 Facial nerve disorders
0.757 0.243 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.756 0.244 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.756 0.244 0.000
C77.2 Intra-abdominal lymph nodes
0.755 0.245 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.751 0.249 0.000
H10-H13 Disorders of conjunctiva
0.750 0.250 0.000
C22.0 Liver cell carcinoma
0.749 0.251 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.749 0.251 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.748 0.252 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.748 0.252 0.000
T78 Adverse effects, not elsewhere classified
0.748 0.252 0.000
S22.30 Fracture of rib (closed)
0.746 0.254 0.000
S40 Superficial injury of shoulder and upper arm
0.746 0.254 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.745 0.255 0.000
F34 Persistent mood [affective] disorders
0.744 0.256 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.744 0.256 0.000
H31 Other disorders of choroid
0.743 0.257 0.000
C66 Malignant neoplasm of ureter
0.742 0.258 0.000
D45 Polycythaemia vera
0.741 0.259 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.740 0.260 0.000
C79.2 Secondary malignant neoplasm of skin
0.740 0.260 0.000
E14 Unspecified diabetes mellitus
0.740 0.260 0.000
H50.5 Heterophoria
0.737 0.263 0.000
F41.2 Mixed anxiety and depressive disorder
0.737 0.263 0.000
C80 Malignant neoplasm without specification of site
0.736 0.264 0.000
C83.3 Large cell (diffuse)
0.736 0.264 0.000
C91 Lymphoid leukaemia
0.735 0.265 0.000
C67.4 Posterior wall of bladder
0.735 0.265 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.734 0.266 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.734 0.266 0.000
H66 Suppurative and unspecified otitis media
0.733 0.267 0.000
G58 Other mononeuropathies
0.733 0.267 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.732 0.268 0.000
C17 Malignant neoplasm of small intestine
0.730 0.270 0.000
G70-G73 Diseases of myoneural junction and muscle
0.730 0.270 0.000
E70-E90 Metabolic disorders
0.730 0.270 0.000
S06 Intracranial injury
0.730 0.270 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.729 0.271 0.000
H49 Paralytic strabismus
0.728 0.272 0.000
S52 Fracture of forearm
0.727 0.273 0.000
S70 Superficial injury of hip and thigh
0.726 0.274 0.000
S42 Fracture of shoulder and upper arm
0.726 0.274 0.000
D04 Carcinoma in situ of skin
0.725 0.275 0.000
W50-W64 Exposure to animate mechanical forces
0.725 0.275 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.724 0.275 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.724 0.276 0.000
F20 Schizophrenia
0.723 0.276 0.000
H81 Disorders of vestibular function
0.722 0.278 0.000
Y58 Bacterial vaccines
0.720 0.280 0.000
S90 Superficial injury of ankle and foot
0.719 0.281 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.716 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
F22 Persistent delusional disorders
0.716 0.284 0.000
W07 Fall involving chair
0.716 0.284 0.000
C95 Leukaemia of unspecified cell type
0.716 0.284 0.000
Q21 Congenital malformations of cardiac septa
0.716 0.284 0.000
C71.9 Brain, unspecified
0.715 0.285 0.000
H40.1 Primary open-angle glaucoma
0.715 0.285 0.000
Y52 Agents primarily affecting the cardiovascular system
0.714 0.286 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.286 0.000
Y10-Y34 Event of undetermined intent
0.713 0.286 0.000
Y00-Y09 Assault
0.713 0.286 0.000
X85-X99 Assault
0.713 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.713 0.286 0.000
X30-X39 Exposure to forces of nature
0.713 0.286 0.000
X10-X19 Contact with heat and hot substances
0.713 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.713 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.713 0.286 0.000
W75-W84 Other accidental threats to breathing
0.713 0.286 0.000
W65-W74 Accidental drowning and submersion
0.713 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.713 0.286 0.000
V95-V97 Air and space transport accidents
0.713 0.286 0.000
V90-V94 Water transport accidents
0.713 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.713 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.713 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.713 0.286 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.712 0.288 0.000
Q60-Q64 Congenital malformations of the urinary system
0.712 0.288 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.711 0.289 0.000
H35.5 Hereditary retinal dystrophy
0.711 0.289 0.000
F38 Other mood [affective] disorders
0.711 0.289 0.000
F39 Unspecified mood [affective] disorder
0.711 0.289 0.000
E40-E46 Malnutrition
0.710 0.290 0.000
E27.1 Primary adrenocortical insufficiency
0.710 0.290 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.710 0.290 0.000
Q35-Q37 Cleft lip and cleft palate
0.710 0.290 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.710 0.290 0.000
Q18 Other congenital malformations of face and neck
0.709 0.291 0.000
V20-V29 Motorcycle rider injured in transport accident
0.709 0.291 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.708 0.292 0.000
Q76 Congenital malformations of spine and bony thorax
0.707 0.293 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.706 0.293 0.000
H30 Chorioretinal inflammation
0.706 0.293 0.000
E23 Hypofunction and other disorders of pituitary gland
0.706 0.294 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.706 0.294 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.705 0.295 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.704 0.296 0.000
Chapter X Diseases of the respiratory system
0.704 0.296 0.000
V80-V89 Other land transport accidents
0.704 0.296 0.000
H35.7 Separation of retinal layers
0.703 0.297 0.000
H35.1 Retinopathy of prematurity
0.703 0.297 0.000
H83.0 Labyrinthitis
0.702 0.298 0.000
X60-X84 Intentional self-harm
0.700 0.300 0.000
Q54 Hypospadias
0.700 0.300 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.700 0.300 0.000
D03.5 Melanoma in situ of trunk
0.700 0.300 0.000
S36 Injury of intra-abdominal organs
0.700 0.300 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.699 0.301 0.000
H73 Other disorders of tympanic membrane
0.699 0.301 0.000
Y44 Agents primarily affecting blood constituents
0.699 0.301 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.698 0.302 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.698 0.302 0.000
W06 Fall involving bed
0.697 0.303 0.000
Q00-Q07 Congenital malformations of the nervous system
0.697 0.303 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.697 0.303 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.697 0.303 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.697 0.303 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.697 0.303 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.697 0.303 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.697 0.303 0.000
T36 Poisoning by systemic antibiotics
0.697 0.303 0.000
H74.0 Tympanosclerosis
0.696 0.304 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.696 0.304 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.695 0.305 0.000
Q27 Other congenital malformations of peripheral vascular system
0.694 0.305 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.694 0.306 0.000
E10 Insulin-dependent diabetes mellitus
0.694 0.306 0.000
G37 Other demyelinating diseases of central nervous system
0.694 0.306 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.693 0.307 0.000
X50-X57 Overexertion, travel and privation
0.693 0.307 0.000
H55-H59 Other disorders of eye and adnexa
0.692 0.307 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.692 0.308 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.692 0.308 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.692 0.308 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.692 0.308 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.690 0.309 0.000
S05 Injury of eye and orbit
0.689 0.311 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.689 0.311 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.689 0.311 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.688 0.311 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.688 0.312 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.686 0.313 0.000
F99 Mental disorder, not otherwise specified
0.686 0.314 0.000
S99 Other and unspecified injuries of ankle and foot
0.684 0.316 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.684 0.316 0.000
C65 Malignant neoplasm of renal pelvis
0.684 0.316 0.000
Q24 Other congenital malformations of heart
0.684 0.316 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.683 0.317 0.000
X20-X29 Contact with venomous animals and plants
0.682 0.318 0.000
E29 Testicular dysfunction
0.682 0.318 0.000
Chapter IX Diseases of the circulatory system
0.682 0.318 0.000
S72 Fracture of femur
0.681 0.319 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.680 0.320 0.000
E27.8 Other specified disorders of adrenal gland
0.679 0.320 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.679 0.321 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.678 0.321 0.000
C22.1 Intrahepatic bile duct carcinoma
0.678 0.322 0.000
H40.0 Glaucoma suspect
0.678 0.322 0.000
F25 Schizoaffective disorders
0.676 0.323 0.000
F23 Acute and transient psychotic disorders
0.676 0.323 0.000
F28 Other nonorganic psychotic disorders
0.676 0.323 0.000
F24 Induced delusional disorder
0.676 0.323 0.000
F21 Schizotypal disorder
0.676 0.323 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.676 0.324 0.000
S91 Open wound of ankle and foot
0.676 0.324 0.000
H74.4 Polyp of middle ear
0.676 0.324 0.000
C16.9 Stomach, unspecified
0.675 0.325 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.675 0.325 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.675 0.325 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.675 0.325 0.000
T42.3 Barbiturates
0.675 0.325 0.000
T42.2 Succinimides and oxazolidinediones
0.675 0.325 0.000
T42.1 Iminostilbenes
0.675 0.325 0.000
T42.0 Hydantoin derivatives
0.675 0.325 0.000
C79.6 Secondary malignant neoplasm of ovary
0.674 0.325 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.674 0.326 0.000
C67.9 Bladder, unspecified
0.674 0.326 0.000
F42 Obsessive-compulsive disorder
0.674 0.326 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.673 0.327 0.000
C16.8 Overlapping lesion of stomach
0.673 0.327 0.000
C16.6 Greater curvature of stomach, unspecified
0.673 0.327 0.000
C16.5 Lesser curvature of stomach, unspecified
0.673 0.327 0.000
C16.4 Pylorus
0.673 0.327 0.000
C16.3 Pyloric antrum
0.673 0.327 0.000
C16.2 Body of stomach
0.673 0.327 0.000
C16.1 Fundus of stomach
0.673 0.327 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.673 0.327 0.000
H69 Other disorders of Eustachian tube
0.673 0.327 0.000
Q85 Phakomatoses, not elsewhere classified
0.673 0.327 0.000
G54 Nerve root and plexus disorders
0.673 0.327 0.000
S79 Other and unspecified injuries of hip and thigh
0.672 0.328 0.000
D09.0 Bladder
0.672 0.328 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.672 0.328 0.000
H51 Other disorders of binocular movement
0.672 0.328 0.000
C34.3 Lower lobe, bronchus or lung
0.671 0.329 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.671 0.329 0.000
Y48 Anaesthetics and therapeutic gases
0.671 0.329 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.670 0.330 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.670 0.330 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.670 0.330 0.000
G92 Toxic encephalopathy
0.670 0.330 0.000
F60.9 Personality disorder, unspecified
0.670 0.330 0.000
G91.9 Hydrocephalus, unspecified
0.669 0.331 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.668 0.331 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.668 0.332 0.000
C71.1 Frontal lobe
0.667 0.333 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.665 0.334 0.000
Y98 Lifestyle-related condition
0.665 0.334 0.000
Y97 Environmental-pollution-related condition
0.665 0.334 0.000
Y96 Work-related condition
0.665 0.334 0.000
D06.9 Cervix, unspecified
0.666 0.334 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.664 0.335 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.664 0.336 0.000
G50 Disorders of trigeminal nerve
0.663 0.337 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.663 0.337 0.000
C94 Other leukaemias of specified cell type
0.663 0.337 0.000
C93 Monocytic leukaemia
0.663 0.337 0.000
C88 Malignant immunoproliferative diseases
0.663 0.337 0.000
C86 Other specified types of T/NK-cell lymphoma
0.663 0.337 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.663 0.337 0.000
H80 Otosclerosis
0.662 0.338 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.661 0.338 0.000
E34 Other endocrine disorders
0.661 0.338 0.000
E32 Diseases of thymus
0.661 0.338 0.000
E31 Polyglandular dysfunction
0.661 0.338 0.000
E30 Disorders of puberty, not elsewhere classified
0.661 0.338 0.000
E26 Hyperaldosteronism
0.661 0.338 0.000
E25 Adrenogenital disorders
0.661 0.338 0.000
E20 Hypoparathyroidism
0.661 0.338 0.000
H25-H28 Disorders of lens
0.662 0.338 0.000
Q28 Other congenital malformations of circulatory system
0.661 0.339 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.661 0.339 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.660 0.340 0.000
C22.9 Liver, unspecified
0.660 0.340 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.659 0.341 0.000
W20 Struck by thrown, projected or falling object
0.659 0.341 0.000
C77.8 Lymph nodes of multiple regions
0.658 0.342 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.658 0.342 0.000
S92 Fracture of foot, except ankle
0.658 0.342 0.000
F31.8 Other bipolar affective disorders
0.658 0.342 0.000
F31.7 Bipolar affective disorder, currently in remission
0.658 0.342 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.658 0.342 0.000
E11 Non-insulin-dependent diabetes mellitus
0.658 0.342 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.658 0.342 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.656 0.344 0.000
Q23 Congenital malformations of aortic and mitral valves
0.656 0.344 0.000
F33.8 Other recurrent depressive disorders
0.655 0.345 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.655 0.345 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.655 0.345 0.000
G52 Disorders of other cranial nerves
0.655 0.345 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.654 0.346 0.000
H70 Mastoiditis and related conditions
0.654 0.346 0.000
H68 Eustachian salpingitis and obstruction
0.654 0.346 0.000
H67 Otitis media in diseases classified elsewhere
0.654 0.346 0.000
H50.8 Other specified strabismus
0.654 0.346 0.000
H50.6 Mechanical strabismus
0.654 0.346 0.000
H50.4 Other and unspecified heterotropia
0.654 0.346 0.000
H50.3 Intermittent heterotropia
0.654 0.346 0.000
H50.2 Vertical strabismus
0.654 0.346 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.653 0.347 0.000
H54 Blindness and low vision
0.653 0.347 0.000
C90.2 Plasmacytoma, extramedullary
0.653 0.347 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.652 0.347 0.000
G93.0 Cerebral cysts
0.652 0.348 0.000
C15.8 Overlapping lesion of oesophagus
0.652 0.348 0.000
C15.4 Middle third of oesophagus
0.652 0.348 0.000
C15.3 Upper third of oesophagus
0.652 0.348 0.000
C15.2 Abdominal part of oesophagus
0.652 0.348 0.000
C15.1 Thoracic part of oesophagus
0.652 0.348 0.000
C15.0 Cervical part of oesophagus
0.652 0.348 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.652 0.348 0.000
C70 Malignant neoplasm of meninges
0.652 0.348 0.000
Q82 Other congenital malformations of skin
0.652 0.348 0.000
T79-T79 Certain early complications of trauma
0.652 0.348 0.000
G57.6 Lesion of plantar nerve
0.650 0.350 0.000
W13 Fall from, out of or through building or structure
0.650 0.350 0.000
S10-S19 Injuries to the neck
0.649 0.350 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.649 0.351 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.649 0.351 0.000
H46 Optic neuritis
0.649 0.351 0.000
E14.9 Without complications
0.649 0.351 0.000
S22.0 Fracture of thoracic vertebra
0.648 0.352 0.000
F30.0 Hypomania
0.648 0.352 0.000
S02 Fracture of skull and facial bones
0.647 0.353 0.000
G93.6 Cerebral oedema
0.647 0.353 0.000
D05.0 Lobular carcinoma in situ
0.647 0.353 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.646 0.354 0.000
S37 Injury of urinary and pelvic organs
0.646 0.354 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.646 0.354 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.646 0.354 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.646 0.354 0.000
S31 Open wound of abdomen, lower back and pelvis
0.646 0.354 0.000
C21 Malignant neoplasm of anus and anal canal
0.646 0.354 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.645 0.355 0.000
Q39 Congenital malformations of oesophagus
0.645 0.355 0.000
C77.4 Inguinal and lower limb lymph nodes
0.645 0.355 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.645 0.355 0.000
G58.9 Mononeuropathy, unspecified
0.644 0.355 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.644 0.356 0.000
C20 Malignant neoplasm of rectum
0.644 0.356 0.000
C07 Malignant neoplasm of parotid gland
0.644 0.356 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.644 0.356 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.643 0.357 0.000
W46 Contact with hypodermic needle
0.643 0.357 0.000
W45 Foreign body or object entering through skin
0.643 0.357 0.000
W43 Exposure to vibration
0.643 0.357 0.000
W42 Exposure to noise
0.643 0.357 0.000
W41 Exposure to high-pressure jet
0.643 0.357 0.000
W40 Explosion of other materials
0.643 0.357 0.000
W39 Discharge of firework
0.643 0.357 0.000
W38 Explosion and rupture of other specified pressurised devices
0.643 0.357 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.643 0.357 0.000
W36 Explosion and rupture of gas cylinder
0.643 0.357 0.000
W35 Explosion and rupture of boiler
0.643 0.357 0.000
W34 Discharge from other and unspecified firearms
0.643 0.357 0.000
W33 Rifle, shotgun and larger firearm discharge
0.643 0.357 0.000
W32 Handgun discharge
0.643 0.357 0.000
W31 Contact with other and unspecified machinery
0.643 0.357 0.000
W30 Contact with agricultural machinery
0.643 0.357 0.000
W28 Contact with powered lawn mower
0.643 0.357 0.000
W27 Contact with nonpowered hand tool
0.643 0.357 0.000
W26 Contact with knife, sword or dagger
0.643 0.357 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.643 0.357 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.643 0.357 0.000
W21 Striking against or struck by sports equipment
0.643 0.357 0.000
E27.9 Disorder of adrenal gland, unspecified
0.640 0.360 0.000
S80-S89 Injuries to the knee and lower leg
0.640 0.360 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.640 0.360 0.000
F41.1 Generalised anxiety disorder
0.640 0.360 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.640 0.360 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.640 0.360 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.640 0.360 0.000
C31 Malignant neoplasm of accessory sinuses
0.640 0.360 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.640 0.360 0.000
C37 Malignant neoplasm of thymus
0.640 0.360 0.000
C33 Malignant neoplasm of trachea
0.640 0.360 0.000
T45.0 Antiallergic and antiemetic drugs
0.639 0.361 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.638 0.362 0.000
Y59 Other and unspecified vaccines and biological substances
0.637 0.363 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.637 0.363 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.637 0.363 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.637 0.363 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.637 0.363 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.637 0.363 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.637 0.363 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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