TreeWAS – Variant ID: rs68085422

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z88.0 Personal history of allergy to penicillin	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001	0.000
Chapter V Mental and behavioural disorders	0.999	0.001	0.000
M05-M14 Inflammatory polyarthropathies	0.998	0.002	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.995	0.005	0.000
F30-F39 Mood [affective] disorders	0.988	0.012	0.000
Chapter XX External causes of morbidity and mortality	0.987	0.013	0.000
M06 Other rheumatoid arthritis	0.981	0.019	0.000
M06.9 Rheumatoid arthritis, unspecified	0.969	0.031	0.000
F31 Bipolar affective disorder	0.965	0.035	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.964	0.036	0.000
Chapter II Neoplasms	0.957	0.043	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.950	0.050	0.000
M05 Seropositive rheumatoid arthritis	0.948	0.052	0.000
S80-S89 Injuries to the knee and lower leg	0.939	0.061	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.936	0.064	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.933	0.067	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.931	0.069	0.000
C44.3 Skin of other and unspecified parts of face	0.931	0.069	0.000
C44 Other malignant neoplasms of skin	0.924	0.076	0.000
Chapter I Certain infectious and parasitic diseases	0.923	0.077	0.000
F41 Other anxiety disorders	0.917	0.083	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.914	0.086	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.913	0.087	0.000
F33 Recurrent depressive disorder	0.912	0.088	0.000
Chapter VII Diseases of the eye and adnexa	0.906	0.094	0.000
F31.9 Bipolar affective disorder, unspecified	0.903	0.097	0.000
M13 Other arthritis	0.903	0.097	0.000
F41.2 Mixed anxiety and depressive disorder	0.903	0.097	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.888	0.112	0.000
M50-M54 Other dorsopathies	0.886	0.114	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.885	0.115	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.882	0.118	0.000
C60-C63 Malignant neoplasms of male genital organs	0.879	0.121	0.000
S82 Fracture of lower leg, including ankle	0.873	0.127	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.864	0.136	0.000
M50 Cervical disk disorders	0.855	0.145	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.846	0.154	0.000
T66-T78 Other and unspecified effects of external causes	0.842	0.158	0.000
M80-M85 Disorders of bone density and structure	0.841	0.159	0.000
X20-X29 Contact with venomous animals and plants	0.838	0.162	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.837	0.163	0.000
C61 Malignant neoplasm of prostate	0.836	0.164	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.836	0.164	0.000
Chapter XIV Diseases of the genitourinary system	0.835	0.165	0.000
M13.9 Arthritis, unspecified	0.835	0.165	0.000
W20-W49 Exposure to inanimate mechanical forces	0.827	0.173	0.000
F33.9 Recurrent depressive disorder, unspecified	0.826	0.174	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.825	0.175	0.000
W00-W19 Falls	0.822	0.178	0.000
N60-N64 Disorders of breast	0.820	0.180	0.000
H53-H54 Visual disturbances and blindness	0.817	0.183	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.816	0.184	0.000
A30-A49 Other bacterial diseases	0.814	0.186	0.000
T79-T79 Certain early complications of trauma	0.814	0.186	0.000
H10-H13 Disorders of conjunctiva	0.812	0.188	0.000
K90.0 Coeliac disease	0.000	0.191	0.809
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.808	0.192	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.806	0.194	0.000
B25-B34 Other viral diseases	0.806	0.194	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.805	0.195	0.000
F34 Persistent mood [affective] disorders	0.805	0.195	0.000
Chapter X Diseases of the respiratory system	0.799	0.201	0.000
M50.2 Other cervical disk displacement	0.798	0.202	0.000
F80-F89 Disorders of psychological development	0.797	0.203	0.000
M14 Arthropathies in other diseases classified elsewhere	0.790	0.210	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.789	0.211	0.000
M91-M94 Chondropathies	0.788	0.212	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.786	0.214	0.000
M07 Psoriatic and enteropathic arthropathies	0.786	0.214	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.785	0.215	0.000
M13.96 Arthritis, unspecified (Lower leg)	0.785	0.215	0.000
S82.2 Fracture of shaft of tibia	0.784	0.215	0.000
S70-S79 Injuries to the hip and thigh	0.783	0.217	0.000
S40-S49 Injuries to the shoulder and upper arm	0.782	0.218	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.780	0.220	0.000
B15-B19 Viral hepatitis	0.778	0.222	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.776	0.223	0.000
S82.6 Fracture of lateral malleolus	0.774	0.226	0.000
M70-M79 Other soft tissue disorders	0.773	0.227	0.000
H55-H59 Other disorders of eye and adnexa	0.773	0.227	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.773	0.227	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.770	0.230	0.000
M65-M68 Disorders of synovium and tendon	0.769	0.231	0.000
M00-M03 Infectious arthropathies	0.768	0.232	0.000
F03 Unspecified dementia	0.762	0.238	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.761	0.239	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.758	0.242	0.000
F60-F69 Disorders of adult personality and behaviour	0.756	0.244	0.000
Y52 Agents primarily affecting the cardiovascular system	0.756	0.244	0.000
C44.4 Skin of scalp and neck	0.755	0.245	0.000
A80-A89 Viral infections of the central nervous system	0.755	0.245	0.000
N20-N23 Urolithiasis	0.753	0.247	0.000
N64 Other disorders of breast	0.752	0.248	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.750	0.250	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.750	0.250	0.000
Y42.7 Androgens and anabolic congeners	0.750	0.250	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.749	0.251	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.740	0.260	0.000
Chapter XXII Codes for special purposes	0.738	0.262	0.000
S86 Injury of muscle and tendon at lower leg level	0.735	0.265	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.735	0.265	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.735	0.265	0.000
B99-B99 Other infectious diseases	0.734	0.266	0.000
Q60-Q64 Congenital malformations of the urinary system	0.734	0.266	0.000
T78 Adverse effects, not elsewhere classified	0.732	0.268	0.000
X23 Contact with hornets, wasps and bees	0.731	0.268	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.730	0.270	0.000
M85 Other disorders of bone density and structure	0.730	0.270	0.000
D45 Polycythaemia vera	0.729	0.271	0.000
A49 Bacterial infection of unspecified site	0.729	0.271	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.728	0.272	0.000
X60-X84 Intentional self-harm	0.727	0.272	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.725	0.275	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.725	0.275	0.000
M50.3 Other cervical disk degeneration	0.724	0.276	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.722	0.278	0.000
M13.98 Arthritis, unspecified (Other)	0.722	0.278	0.000
S82.20 Fracture of shaft of tibia (closed)	0.721	0.279	0.000
J09-J18 Influenza and pneumonia	0.720	0.280	0.000
H54 Blindness and low vision	0.719	0.281	0.000
D00-D09 In situ neoplasms	0.719	0.281	0.000
F40 Phobic anxiety disorders	0.718	0.282	0.000
M06.0 Seronegative rheumatoid arthritis	0.718	0.282	0.000
S80 Superficial injury of lower leg	0.717	0.283	0.000
F43 Reaction to severe stress, and adjustment disorders	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
M60-M63 Disorders of muscles	0.716	0.283	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.716	0.284	0.000
F70-F79 Mental retardation	0.716	0.284	0.000
M12 Other specific arthropathies	0.716	0.284	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.716	0.284	0.000
M08 Juvenile arthritis	0.716	0.284	0.000
T33-T35 Frostbite	0.714	0.286	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.714	0.286	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.714	0.286	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.714	0.286	0.000
T00-T07 Injuries involving multiple body regions	0.714	0.286	0.000
S10-S19 Injuries to the neck	0.714	0.286	0.000
H57 Other disorders of eye and adnexa	0.711	0.288	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.711	0.288	0.000
T63 Toxic effect of contact with venomous animals	0.711	0.289	0.000
C51-C58 Malignant neoplasms of female genital organs	0.711	0.289	0.000
Q50-Q56 Congenital malformations of genital organs	0.711	0.289	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.711	0.289	0.000
W22 Striking against or struck by other objects	0.711	0.289	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.710	0.290	0.000
B34 Viral infection of unspecified site	0.710	0.290	0.000
H11 Other disorders of conjunctiva	0.709	0.291	0.000
T40.2 Other opioids	0.709	0.291	0.000
F38 Other mood [affective] disorders	0.709	0.291	0.000
F30 Manic episode	0.709	0.291	0.000
F39 Unspecified mood [affective] disorder	0.709	0.291	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.707	0.293	0.000
Y35-Y36 Legal intervention and operations of war	0.707	0.293	0.000
Y10-Y34 Event of undetermined intent	0.707	0.293	0.000
Y00-Y09 Assault	0.707	0.293	0.000
X85-X99 Assault	0.707	0.293	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.707	0.293	0.000
X50-X57 Overexertion, travel and privation	0.707	0.293	0.000
X30-X39 Exposure to forces of nature	0.707	0.293	0.000
X10-X19 Contact with heat and hot substances	0.707	0.293	0.000
X00-X09 Exposure to smoke, fire and flames	0.707	0.293	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.707	0.293	0.000
W75-W84 Other accidental threats to breathing	0.707	0.293	0.000
W65-W74 Accidental drowning and submersion	0.707	0.293	0.000
W50-W64 Exposure to animate mechanical forces	0.707	0.293	0.000
V98-V99 Other and unspecified transport accidents	0.707	0.293	0.000
V95-V97 Air and space transport accidents	0.707	0.293	0.000
V90-V94 Water transport accidents	0.707	0.293	0.000
V80-V89 Other land transport accidents	0.707	0.293	0.000
V70-V79 Bus occupant injured in transport accident	0.707	0.293	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.707	0.293	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.707	0.293	0.000
V40-V49 Car occupant injured in transport accident	0.707	0.293	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.707	0.293	0.000
V01-V09 Pedestrian injured in transport accident	0.707	0.293	0.000
Y40 Systemic antibiotics	0.706	0.294	0.000
S00-S09 Injuries to the head	0.706	0.294	0.000
V20-V29 Motorcycle rider injured in transport accident	0.705	0.295	0.000
J95-J99 Other diseases of the respiratory system	0.704	0.296	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.704	0.296	0.000
M06.8 Other specified rheumatoid arthritis	0.704	0.296	0.000
M06.4 Inflammatory polyarthropathy	0.704	0.296	0.000
M06.3 Rheumatoid nodule	0.704	0.296	0.000
M06.2 Rheumatoid bursitis	0.704	0.296	0.000
M06.1 Adult-onset Still's disease	0.704	0.296	0.000
S82.60 Fracture of lateral malleolus (closed)	0.703	0.297	0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.701	0.299	0.000
N62 Hypertrophy of breast	0.700	0.300	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.700	0.300	0.000
F99-F99 Unspecified mental disorder	0.698	0.302	0.000
C73 Malignant neoplasm of thyroid gland	0.698	0.302	0.000
N60 Benign mammary dysplasia	0.697	0.303	0.000
M11 Other crystal arthropathies	0.696	0.304	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.695	0.305	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.695	0.305	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.695	0.305	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.695	0.305	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.695	0.305	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.695	0.305	0.000
F31.8 Other bipolar affective disorders	0.692	0.308	0.000
F31.7 Bipolar affective disorder, currently in remission	0.692	0.308	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.692	0.308	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.692	0.308	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.692	0.308	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.692	0.308	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.691	0.308	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.691	0.308	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.691	0.308	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.691	0.308	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.691	0.308	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.691	0.308	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.691	0.308	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.691	0.308	0.000
T36 Poisoning by systemic antibiotics	0.691	0.308	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.690	0.310	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.689	0.311	0.000
M10 Gout	0.688	0.312	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.688	0.312	0.000
S82.4 Fracture of fibula alone	0.688	0.312	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.686	0.314	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.686	0.314	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.686	0.314	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.686	0.314	0.000
T43.2 Other and unspecified antidepressants	0.685	0.315	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.685	0.315	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.683	0.317	0.000
M15-M19 Arthrosis	0.683	0.317	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.683	0.317	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.682	0.318	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.681	0.319	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.681	0.319	0.000
F48 Other neurotic disorders	0.681	0.319	0.000
F44 Dissociative [conversion] disorders	0.681	0.319	0.000
F42 Obsessive-compulsive disorder	0.681	0.319	0.000
M86-M90 Other osteopathies	0.681	0.319	0.000
T39.0 Salicylates	0.681	0.319	0.000
S50-S59 Injuries to the elbow and forearm	0.681	0.319	0.000
M05.8 Other seropositive rheumatoid arthritis	0.680	0.320	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.680	0.320	0.000
M05.2 Rheumatoid vasculitis	0.680	0.320	0.000
M05.1 Rheumatoid lung disease	0.680	0.320	0.000
M05.0 Felty's syndrome	0.680	0.320	0.000
S90-S99 Injuries to the ankle and foot	0.680	0.320	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.679	0.321	0.000
N64.1 Fat necrosis of breast	0.677	0.323	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.676	0.324	0.000
N61 Inflammatory disorders of breast	0.675	0.325	0.000
A49.0 Staphylococcal infection, unspecified	0.675	0.325	0.000
F06.7 Mild cognitive disorder	0.674	0.326	0.000
F34.1 Dysthymia	0.673	0.327	0.000
S88 Traumatic amputation of lower leg	0.673	0.327	0.000
S87 Crushing injury of lower leg	0.673	0.327	0.000
S85 Injury of blood vessels at lower leg level	0.673	0.327	0.000
S84 Injury of nerves at lower leg level	0.673	0.327	0.000
M75 Shoulder lesions	0.673	0.327	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.669	0.331	0.000
N10-N16 Renal tubulo-interstitial diseases	0.669	0.331	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.668	0.332	0.000
Y59 Other and unspecified vaccines and biological substances	0.668	0.332	0.000
Y58 Bacterial vaccines	0.668	0.332	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.668	0.332	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.668	0.332	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.668	0.332	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.668	0.332	0.000
Y48 Anaesthetics and therapeutic gases	0.668	0.332	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.668	0.332	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.668	0.332	0.000
H53 Visual disturbances	0.666	0.334	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.666	0.334	0.000
M20-M25 Other joint disorders	0.665	0.335	0.000
S42 Fracture of shoulder and upper arm	0.665	0.335	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.663	0.336	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.663	0.337	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.663	0.337	0.000
C44.8 Overlapping lesion of skin	0.663	0.337	0.000
S82.8 Fractures of other parts of lower leg	0.662	0.338	0.000
N20 Calculus of kidney and ureter	0.662	0.338	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.661	0.338	0.000
B65-B83 Helminthiases	0.661	0.338	0.000
B50-B64 Protozoal diseases	0.661	0.338	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.661	0.338	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.661	0.338	0.000
A75-A79 Rickettsioses	0.661	0.338	0.000
A70-A74 Other diseases caused by chlamydiae	0.661	0.338	0.000
A65-A69 Other spirochaetal diseases	0.661	0.338	0.000
A20-A28 Certain zoonotic bacterial diseases	0.661	0.338	0.000
A15-A19 Tuberculosis	0.661	0.338	0.000
C64-C68 Malignant neoplasms of urinary tract	0.661	0.339	0.000
H10 Conjunctivitis	0.661	0.339	0.000
S20-S29 Injuries to the thorax	0.661	0.339	0.000
N25-N29 Other disorders of kidney and ureter	0.660	0.340	0.000
Y57 Other and unspecified drugs and medicaments	0.660	0.340	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.659	0.341	0.000
M67 Other disorders of synovium and tendon	0.658	0.342	0.000
F41.8 Other specified anxiety disorders	0.657	0.342	0.000
F41.3 Other mixed anxiety disorders	0.657	0.342	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.655	0.345	0.000
Q80-Q89 Other congenital malformations	0.655	0.345	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.655	0.345	0.000
Q35-Q37 Cleft lip and cleft palate	0.655	0.345	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.655	0.345	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.655	0.345	0.000
Q00-Q07 Congenital malformations of the nervous system	0.655	0.345	0.000
S82.5 Fracture of medial malleolus	0.655	0.345	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.654	0.345	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.654	0.345	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.654	0.345	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.654	0.345	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.654	0.345	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.654	0.345	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.654	0.345	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.654	0.345	0.000
F33.8 Other recurrent depressive disorders	0.654	0.346	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.654	0.346	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.654	0.346	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.654	0.346	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.654	0.346	0.000
M84 Disorders of continuity of bone	0.654	0.346	0.000
H57.1 Ocular pain	0.654	0.346	0.000
S60-S69 Injuries to the wrist and hand	0.653	0.347	0.000
F81 Specific developmental disorders of scholastic skills	0.652	0.348	0.000
Y44 Agents primarily affecting blood constituents	0.652	0.348	0.000
M50.1 Cervical disk disorder with radiculopathy	0.651	0.349	0.000
Q21 Congenital malformations of cardiac septa	0.651	0.349	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.650	0.350	0.000
J11 Influenza, virus not identified	0.650	0.350	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.649	0.351	0.000
Y42.5 Other oestrogens and progestogens	0.649	0.351	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.648	0.352	0.000
M13.8 Other specified arthritis	0.647	0.353	0.000
M13.1 Monoarthritis, not elsewhere classified	0.647	0.353	0.000
M13.0 Polyarthritis, unspecified	0.647	0.353	0.000
B18 Chronic viral hepatitis	0.646	0.353	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.646	0.354	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.645	0.355	0.000
T78.4 Allergy, unspecified	0.643	0.357	0.000
N23 Unspecified renal colic	0.643	0.357	0.000
M50.0 Cervical disk disorder with myelopathy	0.642	0.358	0.000
F41.1 Generalised anxiety disorder	0.642	0.358	0.000
B34.9 Viral infection, unspecified	0.642	0.358	0.000
M14.6 Neuropathic arthropathy	0.640	0.360	0.000
W17 Other fall from one level to another	0.639	0.361	0.000
T39.1 4-Aminophenol derivatives	0.639	0.361	0.000
M53 Other dorsopathies, not elsewhere classified	0.639	0.361	0.000
H25-H28 Disorders of lens	0.638	0.362	0.000
M16 Coxarthrosis [arthrosis of hip]	0.638	0.362	0.000
F00 Dementia in Alzheimer's disease	0.638	0.362	0.000
J98 Other respiratory disorders	0.636	0.364	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.635	0.365	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.635	0.365	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.635	0.365	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.635	0.365	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.635	0.365	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.634	0.366	0.000
M94 Other disorders of cartilage	0.634	0.366	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.633	0.367	0.000
M07.3 Other psoriatic arthropathies	0.633	0.367	0.000
S70 Superficial injury of hip and thigh	0.633	0.367	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.633	0.367	0.000
A40 Streptococcal septicaemia	0.633	0.367	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.633	0.367	0.000
F02 Dementia in other diseases classified elsewhere	0.633	0.367	0.000
F09 Unspecified organic or symptomatic mental disorder	0.633	0.367	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.633	0.367	0.000
C63 Malignant neoplasm of other and unspecified male genital organs	0.631	0.369	0.000
C60 Malignant neoplasm of penis	0.631	0.369	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.630	0.370	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.629	0.371	0.000
D47.2 Monoclonal gammopathy	0.628	0.372	0.000
W22.9 Unspecified place	0.628	0.372	0.000
M24 Other specific joint derangements	0.627	0.372	0.000
Q23 Congenital malformations of aortic and mitral valves	0.627	0.373	0.000
S89 Other and unspecified injuries of lower leg	0.627	0.373	0.000
S82.9 Fracture of lower leg, part unspecified	0.626	0.374	0.000
S82.7 Multiple fractures of lower leg	0.626	0.374	0.000
H54.7 Unspecified visual loss	0.625	0.375	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.625	0.375	0.000
W25 Contact with sharp glass	0.624	0.375	0.000
Y85 Sequelae of transport accidents	0.624	0.376	0.000
T51 Toxic effect of alcohol	0.622	0.378	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.622	0.378	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.622	0.378	0.000
T63.4 Venom of other arthropods	0.621	0.379	0.000
C43 Malignant melanoma of skin	0.620	0.380	0.000
S79 Other and unspecified injuries of hip and thigh	0.619	0.381	0.000
M80 Osteoporosis with pathological fracture	0.619	0.381	0.000
F22 Persistent delusional disorders	0.619	0.381	0.000
W07 Fall involving chair	0.618	0.382	0.000
N64.5 Other signs and symptoms in breast	0.617	0.383	0.000
C50-C50 Malignant neoplasm of breast	0.617	0.383	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.616	0.384	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.616	0.384	0.000
W02.9 Unspecified place	0.614	0.386	0.000
M13.94 Arthritis, unspecified (Hand)	0.614	0.386	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.613	0.387	0.000
N63 Unspecified lump in breast	0.613	0.387	0.000
M50.9 Cervical disk disorder, unspecified	0.613	0.387	0.000
M50.8 Other cervical disk disorders	0.613	0.387	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.613	0.387	0.000
T45.0 Antiallergic and antiemetic drugs	0.611	0.389	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.610	0.390	0.000
J00-J06 Acute upper respiratory infections	0.610	0.390	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.609	0.391	0.000
M85.0 Fibrous dysplasia (monostotic)	0.609	0.391	0.000
A86 Unspecified viral encephalitis	0.608	0.391	0.000
X23.9 Unspecified place	0.608	0.392	0.000
T43.9 Psychotropic drug, unspecified	0.606	0.394	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.606	0.394	0.000
T43.6 Psychostimulants with abuse potential	0.606	0.394	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.606	0.394	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.606	0.394	0.000
B25 Cytomegaloviral disease	0.606	0.394	0.000
B17 Other acute viral hepatitis	0.605	0.395	0.000
N20.1 Calculus of ureter	0.605	0.395	0.000
T75 Effects of other external causes	0.604	0.396	0.000
T74 Maltreatment syndromes	0.604	0.396	0.000
T73 Effects of other deprivation	0.604	0.396	0.000
T70 Effects of air pressure and water pressure	0.604	0.396	0.000
T69 Other effects of reduced temperature	0.604	0.396	0.000
T67 Effects of heat and light	0.604	0.396	0.000
T71 Asphyxiation	0.604	0.396	0.000
T68 Hypothermia	0.604	0.396	0.000
T66 Unspecified effects of radiation	0.604	0.396	0.000
X23.0 Home	0.603	0.396	0.000
M83 Adult osteomalacia	0.603	0.397	0.000
M82 Osteoporosis in diseases classified elsewhere	0.603	0.397	0.000
M00 Pyogenic arthritis	0.603	0.397	0.000
N99-N99 Other disorders of the genitourinary system	0.602	0.398	0.000
X29 Contact with unspecified venomous animal or plant	0.601	0.399	0.000
X28 Contact with other specified venomous plants	0.601	0.399	0.000
X27 Contact with other specified venomous animals	0.601	0.399	0.000
X26 Contact with venomous marine animals and plants	0.601	0.399	0.000
X25 Contact with other specified venomous arthropods	0.601	0.399	0.000
X24 Contact with centipedes and venomous millipedes (tropical)	0.601	0.399	0.000
X22 Contact with scorpions	0.601	0.399	0.000
X21 Contact with venomous spiders	0.601	0.399	0.000
X20 Contact with venomous snakes and lizards	0.601	0.399	0.000
W10 Fall on and from stairs and steps	0.600	0.400	0.000
H43-H45 Disorders of vitreous body and globe	0.600	0.400	0.000
C01 Malignant neoplasm of base of tongue	0.600	0.400	0.000
T65 Toxic effect of other and unspecified substances	0.600	0.400	0.000
T62 Toxic effect of other noxious substances eaten as food	0.600	0.400	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.600	0.400	0.000
T60 Toxic effect of pesticides	0.600	0.400	0.000
T59 Toxic effect of other gases, fumes and vapours	0.600	0.400	0.000
T57 Toxic effect of other inorganic substances	0.600	0.400	0.000
T56 Toxic effect of metals	0.600	0.400	0.000
T54 Toxic effect of corrosive substances	0.600	0.400	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.600	0.400	0.000
T52 Toxic effect of organic solvents	0.600	0.400	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.600	0.400	0.000
T58 Toxic effect of carbon monoxide	0.600	0.400	0.000
T55 Toxic effect of soaps and detergents	0.600	0.400	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.600	0.400	0.000
Y42.9 Other and unspecified hormone antagonists	0.599	0.400	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.599	0.400	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.599	0.400	0.000
Y42.4 Oral contraceptives	0.599	0.400	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.599	0.400	0.000
Y42.2 Antithyroid drugs	0.599	0.400	0.000
Y42.1 Thyroid hormones and substitutes	0.599	0.400	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.599	0.400	0.000
B99 Other and unspecified infectious diseases	0.599	0.401	0.000
A00-A09 Intestinal infectious diseases	0.599	0.401	0.000
M13.93 Arthritis, unspecified (Forearm)	0.598	0.402	0.000
M13.92 Arthritis, unspecified (Upper arm)	0.598	0.402	0.000
C09 Malignant neoplasm of tonsil	0.597	0.403	0.000
D46 Myelodysplastic syndromes	0.596	0.404	0.000
M40-M43 Deforming dorsopathies	0.596	0.404	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.595	0.405	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.595	0.405	0.000
J10 Influenza due to identified influenza virus	0.595	0.405	0.000
Y49.2 Other and unspecified antidepressants	0.595	0.405	0.000
W49 Exposure to other and unspecified inanimate mechanical forces	0.593	0.407	0.000
W46 Contact with hypodermic needle	0.593	0.407	0.000
W45 Foreign body or object entering through skin	0.593	0.407	0.000
W43 Exposure to vibration	0.593	0.407	0.000
W42 Exposure to noise	0.593	0.407	0.000
W41 Exposure to high-pressure jet	0.593	0.407	0.000
W40 Explosion of other materials	0.593	0.407	0.000
W39 Discharge of firework	0.593	0.407	0.000
W38 Explosion and rupture of other specified pressurised devices	0.593	0.407	0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.593	0.407	0.000
W36 Explosion and rupture of gas cylinder	0.593	0.407	0.000
W35 Explosion and rupture of boiler	0.593	0.407	0.000
W34 Discharge from other and unspecified firearms	0.593	0.407	0.000
W33 Rifle, shotgun and larger firearm discharge	0.593	0.407	0.000
W32 Handgun discharge	0.593	0.407	0.000
W31 Contact with other and unspecified machinery	0.593	0.407	0.000
W30 Contact with agricultural machinery	0.593	0.407	0.000
W28 Contact with powered lawn mower	0.593	0.407	0.000
W27 Contact with nonpowered hand tool	0.593	0.407	0.000
W26 Contact with knife, sword or dagger	0.593	0.407	0.000
W24 Contact with lifting and transmission devices, not elsewhere classified	0.593	0.407	0.000
W23 Caught, crushed, jammed or pinched in or between objects	0.593	0.407	0.000
W21 Striking against or struck by sports equipment	0.593	0.407	0.000
W20 Struck by thrown, projected or falling object	0.593	0.407	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations