TreeWAS – Variant ID: rs6912584

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E83.1 Disorders of iron metabolism	0.000	0.001	0.999
E20-E35 Disorders of other endocrine glands	0.997	0.003	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.997	0.003	0.000
E16 Other disorders of pancreatic internal secretion	0.995	0.005	0.000
E16.2 Hypoglycaemia, unspecified	0.993	0.007	0.000
R31 Unspecified haematuria	0.000	0.008	0.992
E27 Other disorders of adrenal gland	0.992	0.008	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.988	0.012	0.000
E27.1 Primary adrenocortical insufficiency	0.986	0.014	0.000
C15-C26 Malignant neoplasms of digestive organs	0.986	0.014	0.000
Chapter II Neoplasms	0.984	0.016	0.000
C25 Malignant neoplasm of pancreas	0.983	0.017	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.983	0.017	0.000
C25.9 Pancreas, unspecified	0.978	0.022	0.000
# Top node	0.973	0.027	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.972	0.028	0.000
L40-L45 Papulosquamous disorders	0.972	0.028	0.000
L40 Psoriasis	0.971	0.029	0.000
L50-L54 Urticaria and erythema	0.968	0.032	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.967	0.033	0.000
D00-D09 In situ neoplasms	0.966	0.034	0.000
L53 Other erythematous conditions	0.962	0.038	0.000
L53.9 Erythematous condition, unspecified	0.951	0.049	0.000
D60-D64 Aplastic and other anaemias	0.949	0.051	0.000
L40.9 Psoriasis, unspecified	0.945	0.055	0.000
E13 Other specified diabetes mellitus	0.944	0.056	0.000
D80-D89 Certain disorders involving the immune mechanism	0.944	0.056	0.000
D64 Other anaemias	0.940	0.060	0.000
D64.9 Anaemia, unspecified	0.936	0.064	0.000
E10.3 With ophthalmic complications	0.933	0.067	0.000
C15 Malignant neoplasm of oesophagus	0.930	0.070	0.000
D86 Sarcoidosis	0.920	0.080	0.000
C04 Malignant neoplasm of floor of mouth	0.917	0.083	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.916	0.084	0.000
E10.1 With ketoacidosis	0.914	0.086	0.000
D03 Melanoma in situ	0.911	0.089	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.905	0.095	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.903	0.097	0.000
E14 Unspecified diabetes mellitus	0.902	0.098	0.000
E13.9 Without complications	0.900	0.100	0.000
D86.9 Sarcoidosis, unspecified	0.899	0.101	0.000
L40.5 Arthropathic psoriasis	0.896	0.104	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.893	0.107	0.000
C03 Malignant neoplasm of gum	0.892	0.108	0.000
D03.5 Melanoma in situ of trunk	0.889	0.111	0.000
S00-S09 Injuries to the head	0.886	0.114	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.881	0.119	0.000
S02 Fracture of skull and facial bones	0.879	0.121	0.000
D04 Carcinoma in situ of skin	0.873	0.127	0.000
L10-L14 Bullous disorders	0.870	0.130	0.000
S20-S29 Injuries to the thorax	0.867	0.133	0.000
L43 Lichen planus	0.862	0.138	0.000
L40.0 Psoriasis vulgaris	0.861	0.139	0.000
C13 Malignant neoplasm of hypopharynx	0.860	0.140	0.000
E14.3 With ophthalmic complications	0.858	0.142	0.000
E10.2 With renal complications	0.857	0.143	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.857	0.143	0.000
C15.9 Oesophagus, unspecified	0.856	0.144	0.000
D06 Carcinoma in situ of cervix uteri	0.855	0.145	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.854	0.146	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.853	0.147	0.000
S02.4 Fracture of malar and maxillary bones	0.845	0.155	0.000
C22.1 Intrahepatic bile duct carcinoma	0.842	0.158	0.000
S80-S89 Injuries to the knee and lower leg	0.837	0.163	0.000
C04.9 Floor of mouth, unspecified	0.836	0.164	0.000
D61 Other aplastic anaemias	0.834	0.166	0.000
E83 Disorders of mineral metabolism	0.001	0.167	0.832
C02.9 Tongue, unspecified	0.833	0.167	0.000
S20 Superficial injury of thorax	0.831	0.169	0.000
S40-S49 Injuries to the shoulder and upper arm	0.831	0.169	0.000
C16 Malignant neoplasm of stomach	0.827	0.173	0.000
C25.0 Head of pancreas	0.823	0.177	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.821	0.179	0.000
E10.4 With neurological complications	0.820	0.180	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.820	0.180	0.000
E83.3 Disorders of phosphorus metabolism	0.000	0.183	0.817
C49 Malignant neoplasm of other connective and soft tissue	0.817	0.183	0.000
E29 Testicular dysfunction	0.812	0.188	0.000
L40.3 Pustulosis palmaris et plantaris	0.811	0.189	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.811	0.189	0.000
S02.3 Fracture of orbital floor	0.811	0.189	0.000
L53.8 Other specified erythematous conditions	0.808	0.192	0.000
L52 Erythema nodosum	0.806	0.194	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.806	0.194	0.000
L43.9 Lichen planus, unspecified	0.805	0.195	0.000
S05 Injury of eye and orbit	0.804	0.196	0.000
S21 Open wound of thorax	0.803	0.197	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.803	0.197	0.000
C25.3 Pancreatic duct	0.799	0.201	0.000
L53.0 Toxic erythema	0.799	0.201	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.798	0.202	0.000
T66-T78 Other and unspecified effects of external causes	0.791	0.209	0.000
S80 Superficial injury of lower leg	0.790	0.210	0.000
S20.2 Contusion of thorax	0.790	0.210	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.788	0.212	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.781	0.219	0.000
C01 Malignant neoplasm of base of tongue	0.781	0.219	0.000
D86.8 Sarcoidosis of other and combined sites	0.780	0.220	0.000
E10.7 With multiple complications	0.776	0.224	0.000
C15.4 Middle third of oesophagus	0.774	0.226	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.773	0.227	0.000
E31 Polyglandular dysfunction	0.773	0.227	0.000
D06.9 Cervix, unspecified	0.772	0.228	0.000
E21.3 Hyperparathyroidism, unspecified	0.771	0.229	0.000
E05.8 Other thyrotoxicosis	0.770	0.230	0.000
E20 Hypoparathyroidism	0.769	0.231	0.000
E24 Cushing's syndrome	0.768	0.232	0.000
C04.0 Anterior floor of mouth	0.767	0.233	0.000
E34 Other endocrine disorders	0.767	0.233	0.000
C03.1 Lower gum	0.766	0.234	0.000
L40.4 Guttate psoriasis	0.765	0.234	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.765	0.235	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.763	0.237	0.000
C16.5 Lesser curvature of stomach, unspecified	0.763	0.237	0.000
E25 Adrenogenital disorders	0.762	0.238	0.000
S02.30 Fracture of orbital floor (closed)	0.762	0.238	0.000
E23 Hypofunction and other disorders of pituitary gland	0.762	0.238	0.000
C03.9 Gum, unspecified	0.761	0.239	0.000
E27.2 Addisonian crisis	0.760	0.240	0.000
S02.2 Fracture of nasal bones	0.760	0.240	0.000
E10.0 With coma	0.758	0.241	0.000
E10.5 With peripheral circulatory complications	0.758	0.241	0.000
D83 Common variable immunodeficiency	0.758	0.242	0.000
E03.1 Congenital hypothyroidism without goitre	0.754	0.246	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.746	0.254	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.746	0.254	0.000
C49.0 Connective and soft tissue of head, face and neck	0.745	0.255	0.000
L51 Erythema multiforme	0.739	0.261	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.739	0.261	0.000
C11 Malignant neoplasm of nasopharynx	0.737	0.263	0.000
L40.1 Generalised pustular psoriasis	0.736	0.264	0.000
C05 Malignant neoplasm of palate	0.735	0.265	0.000
C10 Malignant neoplasm of oropharynx	0.734	0.266	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.733	0.267	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.731	0.269	0.000
D09 Carcinoma in situ of other and unspecified sites	0.730	0.270	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.727	0.272	0.000
C13.9 Hypopharynx, unspecified	0.727	0.273	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.726	0.274	0.000
D61.9 Aplastic anaemia, unspecified	0.726	0.274	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.726	0.274	0.000
C25.4 Endocrine pancreas	0.726	0.274	0.000
C15.0 Cervical part of oesophagus	0.725	0.275	0.000
C12 Malignant neoplasm of pyriform sinus	0.725	0.275	0.000
D84 Other immunodeficiencies	0.723	0.277	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.723	0.277	0.000
Q00-Q07 Congenital malformations of the nervous system	0.723	0.277	0.000
E10.6 With other specified complications	0.723	0.277	0.000
E16.1 Other hypoglycaemia	0.722	0.277	0.000
C22.9 Liver, unspecified	0.721	0.279	0.000
C25.7 Other parts of pancreas	0.721	0.279	0.000
D04.2 Skin of ear and external auricular canal	0.720	0.279	0.000
L13 Other bullous disorders	0.718	0.282	0.000
S86 Injury of muscle and tendon at lower leg level	0.717	0.283	0.000
S02.5 Fracture of tooth	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
S05.1 Contusion of eyeball and orbital tissues	0.716	0.284	0.000
S80.8 Other superficial injuries of lower leg	0.716	0.284	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.715	0.285	0.000
E32 Diseases of thymus	0.715	0.285	0.000
E30 Disorders of puberty, not elsewhere classified	0.715	0.285	0.000
E15 Nondiabetic hypoglycaemic coma	0.715	0.285	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.713	0.287	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.713	0.287	0.000
E16.4 Abnormal secretion of gastrin	0.713	0.287	0.000
E16.3 Increased secretion of glucagon	0.713	0.287	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.713	0.287	0.000
C09 Malignant neoplasm of tonsil	0.712	0.288	0.000
C23 Malignant neoplasm of gallbladder	0.712	0.288	0.000
L11 Other acantholytic disorders	0.712	0.288	0.000
Q50-Q56 Congenital malformations of genital organs	0.712	0.288	0.000
C07 Malignant neoplasm of parotid gland	0.711	0.288	0.000
E27.5 Adrenomedullary hyperfunction	0.711	0.289	0.000
E27.0 Other adrenocortical overactivity	0.711	0.289	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.711	0.289	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.710	0.290	0.000
S21.1 Open wound of front wall of thorax	0.708	0.292	0.000
D04.6 Skin of upper limb, including shoulder	0.707	0.293	0.000
E40-E46 Malnutrition	0.706	0.294	0.000
C25.8 Overlapping lesion of pancreas	0.705	0.295	0.000
C25.1 Body of pancreas	0.705	0.295	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.705	0.295	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.702	0.298	0.000
C15.1 Thoracic part of oesophagus	0.700	0.300	0.000
E13.3 With ophthalmic complications	0.700	0.300	0.000
C13.0 Postcricoid region	0.699	0.300	0.000
D80 Immunodeficiency with predominantly antibody defects	0.699	0.300	0.000
C06.0 Cheek mucosa	0.699	0.301	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.697	0.303	0.000
L44 Other papulosquamous disorders	0.697	0.303	0.000
L41 Parapsoriasis	0.697	0.303	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.697	0.303	0.000
C49.3 Connective and soft tissue of thorax	0.697	0.303	0.000
D69 Purpura and other haemorrhagic conditions	0.696	0.304	0.000
D04.7 Skin of lower limb, including hip	0.696	0.304	0.000
L40.2 Acrodermatitis continua	0.696	0.304	0.000
S20.3 Other superficial injuries of front wall of thorax	0.695	0.305	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.694	0.306	0.000
L54 Erythema in diseases classified elsewhere	0.694	0.306	0.000
E27.9 Disorder of adrenal gland, unspecified	0.693	0.307	0.000
E14.4 With neurological complications	0.693	0.307	0.000
L42 Pityriasis rosea	0.693	0.307	0.000
S21.9 Open wound of thorax, part unspecified	0.691	0.309	0.000
T16 Foreign body in ear	0.691	0.309	0.000
C25.2 Tail of pancreas	0.691	0.309	0.000
E14.5 With peripheral circulatory complications	0.690	0.310	0.000
L53.3 Other chronic figurate erythema	0.690	0.310	0.000
L53.2 Erythema marginatum	0.690	0.310	0.000
L53.1 Erythema annulare centrifugum	0.690	0.310	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.687	0.313	0.000
S42 Fracture of shoulder and upper arm	0.687	0.313	0.000
S08 Traumatic amputation of part of head	0.686	0.314	0.000
L12 Pemphigoid	0.684	0.316	0.000
D04.5 Skin of trunk	0.684	0.316	0.000
T79-T79 Certain early complications of trauma	0.681	0.319	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.681	0.319	0.000
S82 Fracture of lower leg, including ankle	0.680	0.320	0.000
E29.1 Testicular hypofunction	0.678	0.322	0.000
E13.8 With unspecified complications	0.677	0.323	0.000
E13.7 With multiple complications	0.677	0.323	0.000
E13.6 With other specified complications	0.677	0.323	0.000
E13.5 With peripheral circulatory complications	0.677	0.323	0.000
E13.4 With neurological complications	0.677	0.323	0.000
E13.2 With renal complications	0.677	0.323	0.000
E13.1 With ketoacidosis	0.677	0.323	0.000
E13.0 With coma	0.677	0.323	0.000
D82 Immunodeficiency associated with other major defects	0.677	0.323	0.000
D81 Combined immunodeficiencies	0.677	0.323	0.000
E34.9 Endocrine disorder, unspecified	0.676	0.324	0.000
D61.0 Constitutional aplastic anaemia	0.676	0.324	0.000
D04.3 Skin of other and unspecified parts of face	0.675	0.325	0.000
E83.4 Disorders of magnesium metabolism	0.000	0.325	0.675
T15 Foreign body on external eye	0.674	0.325	0.000
D64.4 Congenital dyserythropoietic anaemia	0.674	0.326	0.000
D64.3 Other sideroblastic anaemias	0.674	0.326	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.674	0.326	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.674	0.326	0.000
D64.0 Hereditary sideroblastic anaemia	0.674	0.326	0.000
C00 Malignant neoplasm of lip	0.674	0.326	0.000
D03.8 Melanoma in situ of other sites	0.671	0.329	0.000
C15.8 Overlapping lesion of oesophagus	0.667	0.333	0.000
C15.2 Abdominal part of oesophagus	0.667	0.333	0.000
S80.0 Contusion of knee	0.664	0.336	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.663	0.337	0.000
S29 Other and unspecified injuries of thorax	0.662	0.338	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.661	0.339	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.660	0.340	0.000
C04.8 Overlapping lesion of floor of mouth	0.657	0.342	0.000
C04.1 Lateral floor of mouth	0.657	0.342	0.000
S02.20 Fracture of nasal bones (closed)	0.657	0.343	0.000
C16.8 Overlapping lesion of stomach	0.656	0.344	0.000
D03.9 Melanoma in situ, unspecified	0.653	0.346	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.653	0.346	0.000
D03.0 Melanoma in situ of lip	0.653	0.346	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.653	0.347	0.000
S82.4 Fracture of fibula alone	0.653	0.347	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.653	0.347	0.000
T18 Foreign body in alimentary tract	0.653	0.347	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.651	0.349	0.000
Q40 Other congenital malformations of upper alimentary tract	0.650	0.349	0.000
C22.7 Other specified carcinomas of liver	0.649	0.351	0.000
C22.4 Other sarcomas of liver	0.649	0.351	0.000
C22.3 Angiosarcoma of liver	0.649	0.351	0.000
C22.2 Hepatoblastoma	0.649	0.351	0.000
C24.0 Extrahepatic bile duct	0.648	0.352	0.000
T33-T35 Frostbite	0.647	0.353	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.647	0.353	0.000
E14.1 With ketoacidosis	0.647	0.353	0.000
E14.6 With other specified complications	0.647	0.353	0.000
E14.7 With multiple complications	0.646	0.353	0.000
E14.0 With coma	0.646	0.353	0.000
T68 Hypothermia	0.647	0.353	0.000
C49.9 Connective and soft tissue, unspecified	0.646	0.354	0.000
D86.3 Sarcoidosis of skin	0.645	0.355	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.645	0.355	0.000
Q44.5 Other congenital malformations of bile ducts	0.645	0.355	0.000
Q43 Other congenital malformations of intestine	0.644	0.356	0.000
C02.2 Ventral surface of tongue	0.644	0.356	0.000
S02.7 Multiple fractures involving skull and facial bones	0.644	0.356	0.000
S46.3 Injury of muscle and tendon of triceps	0.644	0.356	0.000
S02.8 Fractures of other skull and facial bones	0.641	0.359	0.000
C02.8 Overlapping lesion of tongue	0.640	0.360	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.640	0.360	0.000
C02.0 Dorsal surface of tongue	0.640	0.360	0.000
C03.0 Upper gum	0.639	0.360	0.000
D04.9 Skin, unspecified	0.639	0.361	0.000
S02.6 Fracture of mandible	0.638	0.362	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.637	0.363	0.000
C17 Malignant neoplasm of small intestine	0.636	0.364	0.000
S07 Crushing injury of head	0.635	0.365	0.000
S04 Injury of cranial nerves	0.635	0.365	0.000
T78 Adverse effects, not elsewhere classified	0.635	0.365	0.000
S20.4 Other superficial injuries of back wall of thorax	0.634	0.366	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.633	0.367	0.000
S82.40 Fracture of fibula alone (closed)	0.633	0.367	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.632	0.368	0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.631	0.368	0.000
C46 Kaposi's sarcoma	0.631	0.368	0.000
D03.4 Melanoma in situ of scalp and neck	0.631	0.369	0.000
E21.0 Primary hyperparathyroidism	0.631	0.369	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.631	0.369	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.631	0.369	0.000
E24.2 Drug-induced Cushing's syndrome	0.631	0.369	0.000
D86.1 Sarcoidosis of lymph nodes	0.630	0.370	0.000
S82.0 Fracture of patella	0.630	0.370	0.000
Q39 Congenital malformations of oesophagus	0.629	0.371	0.000
S02.0 Fracture of vault of skull	0.629	0.371	0.000
C15.3 Upper third of oesophagus	0.629	0.371	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.628	0.372	0.000
S24 Injury of nerves and spinal cord at thorax level	0.628	0.372	0.000
C15.5 Lower third of oesophagus	0.628	0.372	0.000
C02.4 Lingual tonsil	0.627	0.372	0.000
C02.1 Border of tongue	0.627	0.373	0.000
C45 Mesothelioma	0.627	0.373	0.000
D04.8 Skin of other sites	0.626	0.374	0.000
D04.0 Skin of lip	0.626	0.374	0.000
C91 Lymphoid leukaemia	0.625	0.375	0.000
D83.9 Common variable immunodeficiency, unspecified	0.625	0.375	0.000
S00 Superficial injury of head	0.625	0.375	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.624	0.376	0.000
L10 Pemphigus	0.624	0.376	0.000
L14 Bullous disorders in diseases classified elsewhere	0.624	0.376	0.000
D06.0 Endocervix	0.623	0.377	0.000
E07 Other disorders of thyroid	0.623	0.377	0.000
C32 Malignant neoplasm of larynx	0.623	0.377	0.000
D69.4 Other primary thrombocytopenia	0.623	0.377	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.621	0.379	0.000
S26 Injury of heart	0.621	0.379	0.000
S25 Injury of blood vessels of thorax	0.621	0.379	0.000
E06 Thyroiditis	0.620	0.380	0.000
L50 Urticaria	0.620	0.380	0.000
L43.3 Subacute (active) lichen planus	0.618	0.382	0.000
L43.2 Lichenoid drug reaction	0.618	0.382	0.000
L43.1 Bullous lichen planus	0.618	0.382	0.000
L43.0 Hypertrophic lichen planus	0.618	0.382	0.000
C13.8 Overlapping lesion of hypopharynx	0.617	0.383	0.000
C13.2 Posterior wall of hypopharynx	0.617	0.383	0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect	0.617	0.383	0.000
S80.9 Superficial injury of lower leg, unspecified	0.616	0.384	0.000
E23.2 Diabetes insipidus	0.615	0.385	0.000
C71 Malignant neoplasm of brain	0.615	0.385	0.000
E24.0 Pituitary-dependent Cushing's disease	0.614	0.386	0.000
D06.7 Other parts of cervix	0.613	0.387	0.000
D06.1 Exocervix	0.613	0.387	0.000
Q35-Q37 Cleft lip and cleft palate	0.612	0.387	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.612	0.387	0.000
E31.0 Autoimmune polyglandular failure	0.612	0.388	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.612	0.388	0.000
E21.4 Other specified disorders of parathyroid gland	0.612	0.388	0.000
E21.2 Other hyperparathyroidism	0.612	0.388	0.000
Q45 Other congenital malformations of digestive system	0.610	0.390	0.000
L13.0 Dermatitis herpetiformis	0.610	0.390	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.608	0.392	0.000
D55-D59 Haemolytic anaemias	0.608	0.392	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.608	0.392	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.607	0.393	0.000
C84.0 Mycosis fungoides	0.607	0.393	0.000
C06.2 Retromolar area	0.607	0.393	0.000
Q76 Congenital malformations of spine and bony thorax	0.607	0.393	0.000
T66 Unspecified effects of radiation	0.606	0.394	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.606	0.394	0.000
C24.9 Biliary tract, unspecified	0.606	0.394	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.605	0.395	0.000
E20.9 Hypoparathyroidism, unspecified	0.605	0.395	0.000
S06 Intracranial injury	0.604	0.396	0.000
C05.9 Palate, unspecified	0.604	0.396	0.000
L51.9 Erythema multiforme, unspecified	0.603	0.397	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.602	0.398	0.000
S02.50 Fracture of tooth (closed)	0.602	0.398	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.601	0.399	0.000
C84.5 Other and unspecified T-cell lymphomas	0.601	0.399	0.000
E28 Ovarian dysfunction	0.601	0.399	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.600	0.400	0.000
C71.1 Frontal lobe	0.600	0.400	0.000
S88 Traumatic amputation of lower leg	0.600	0.400	0.000
S87 Crushing injury of lower leg	0.600	0.400	0.000
S85 Injury of blood vessels at lower leg level	0.600	0.400	0.000
S84 Injury of nerves at lower leg level	0.600	0.400	0.000
E10.8 With unspecified complications	0.599	0.401	0.000
L11.0 Acquired keratosis follicularis	0.599	0.401	0.000
D86.0 Sarcoidosis of lung	0.599	0.401	0.000
E14.2 Withrenal complications	0.598	0.402	0.000
D61.8 Other specified aplastic anaemias	0.598	0.402	0.000
D61.3 Idiopathic aplastic anaemia	0.598	0.402	0.000
D61.2 Aplastic anaemia due to other external agents	0.598	0.402	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.001	0.402	0.597
E83.8 Other disorders of mineral metabolism	0.001	0.402	0.597
E83.2 Disorders of zinc metabolism	0.001	0.402	0.597
E83.0 Disorders of copper metabolism	0.001	0.402	0.597
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.597	0.403	0.000
S20.7 Multiple superficial injuries of thorax	0.596	0.404	0.000
S48 Traumatic amputation of shoulder and upper arm	0.596	0.404	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.596	0.404	0.000
S44 Injury of nerves at shoulder and upper arm level	0.596	0.404	0.000
S47 Crushing injury of shoulder and upper arm	0.596	0.404	0.000
E03.8 Other specified hypothyroidism	0.595	0.404	0.000
D73 Diseases of spleen	0.596	0.404	0.000
D04.1 Skin of eyelid, including canthus	0.594	0.406	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.594	0.406	0.000
Q44.6 Cystic disease of liver	0.594	0.406	0.000
C16.4 Pylorus	0.593	0.407	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.592	0.408	0.000
S10-S19 Injuries to the neck	0.592	0.408	0.000
C20 Malignant neoplasm of rectum	0.592	0.408	0.000
C16.9 Stomach, unspecified	0.592	0.408	0.000
C49.6 Connective and soft tissue of trunk, unspecified	0.590	0.409	0.000
S20.0 Contusion of breast	0.589	0.411	0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.588	0.412	0.000
C06.1 Vestibule of mouth	0.588	0.412	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.587	0.413	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.587	0.413	0.000
C49.8 Overlapping lesion of connective and soft tissue	0.586	0.414	0.000
C49.4 Connective and soft tissue of abdomen	0.586	0.414	0.000
C16.6 Greater curvature of stomach, unspecified	0.586	0.414	0.000
C95 Leukaemia of unspecified cell type	0.585	0.415	0.000
C16.0 Cardia	0.585	0.415	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.584	0.416	0.000
S82.00 Fracture of patella (closed)	0.583	0.417	0.000
S21.2 Open wound of back wall of thorax	0.583	0.417	0.000
C70 Malignant neoplasm of meninges	0.582	0.417	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.582	0.418	0.000
E29.9 Testicular dysfunction, unspecified	0.582	0.418	0.000
E29.8 Other testicular dysfunction	0.582	0.418	0.000
E29.0 Testicular hyperfunction	0.582	0.418	0.000
Q03 Congenital hydrocephalus	0.582	0.418	0.000
T71 Asphyxiation	0.581	0.419	0.000
S02.31 Fracture of orbital floor (open)	0.581	0.419	0.000
S02.21 Fracture of nasal bones (open)	0.581	0.419	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.581	0.419	0.000
E22 Hyperfunction of pituitary gland	0.580	0.420	0.000
T15.9 Foreign body on external eye, unspecified	0.580	0.420	0.000
C91.1 Chronic lymphocytic leukaemia	0.579	0.421	0.000
E23.7 Disorder of pituitary gland, unspecified	0.578	0.421	0.000
E50-E64 Other nutritional deficiencies	0.578	0.422	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.578	0.422	0.000
T78.3 Angioneurotic oedema	0.578	0.422	0.000
S05.7 Avulsion of eye	0.576	0.424	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.576	0.424	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.576	0.424	0.000
C06.9 Mouth, unspecified	0.576	0.424	0.000
S21.8 Open wound of other parts of thorax	0.576	0.424	0.000
S21.7 Multiple open wounds of thoracic wall	0.576	0.424	0.000
S21.0 Open wound of breast	0.576	0.424	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.575	0.424	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.575	0.424	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.575	0.424	0.000
C22.0 Liver cell carcinoma	0.575	0.425	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.574	0.426	0.000
C85.1 B-cell lymphoma, unspecified	0.573	0.427	0.000
T56 Toxic effect of metals	0.571	0.429	0.000
Q53 Undescended testicle	0.571	0.429	0.000
S20.1 Other and unspecified superficial injuries of breast	0.569	0.431	0.000
T75 Effects of other external causes	0.569	0.431	0.000
Q04 Other congenital malformations of brain	0.569	0.431	0.000
D69.9 Haemorrhagic condition, unspecified	0.569	0.431	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.568	0.432	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.567	0.432	0.000
T74 Maltreatment syndromes	0.567	0.433	0.000
T73 Effects of other deprivation	0.567	0.433	0.000
T69 Other effects of reduced temperature	0.567	0.433	0.000
T67 Effects of heat and light	0.567	0.433	0.000
C32.1 Supraglottis	0.566	0.434	0.000
C49.1 Connective and soft tissue of upper limb, including shoulder	0.565	0.435	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.565	0.435	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.565	0.435	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.565	0.435	0.000
S80.7 Multiple superficial injuries of lower leg	0.565	0.435	0.000
L40.8 Other psoriasis	0.564	0.436	0.000
E26 Hyperaldosteronism	0.564	0.436	0.000
D00.1 Oesophagus	0.562	0.438	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.562	0.438	0.000
D61.1 Drug-induced aplastic anaemia	0.561	0.438	0.000
C11.9 Nasopharynx, unspecified	0.560	0.440	0.000
D09.0 Bladder	0.560	0.440	0.000
T70 Effects of air pressure and water pressure	0.560	0.440	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.559	0.441	0.000
C86 Other specified types of T/NK-cell lymphoma	0.559	0.441	0.000
C93 Monocytic leukaemia	0.556	0.444	0.000
C10.9 Oropharynx, unspecified	0.556	0.444	0.000
T19 Foreign body in genito-urinary tract	0.556	0.444	0.000
C43 Malignant melanoma of skin	0.555	0.445	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations