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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72727381
log Bayes Factor = 15.1333
Chromosome 15   position 38,823,527  (GRCh37) Explore rs72727381 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.999 0.001 0.000
Chapter VIII Diseases of the ear and mastoid process
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.994 0.006 0.000
E00-E07 Disorders of thyroid gland
0.993 0.007 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.992 0.008 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.991 0.009 0.000
E03 Other hypothyroidism
0.990 0.010 0.000
E03.9 Hypothyroidism, unspecified
0.988 0.012 0.000
Chapter II Neoplasms
0.987 0.013 0.000
Chapter I Certain infectious and parasitic diseases
0.983 0.017 0.000
Z50 Care involving use of rehabilitation procedures
0.981 0.019 0.000
Chapter IX Diseases of the circulatory system
0.980 0.020 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.979 0.021 0.000
E10-E14 Diabetes mellitus
0.973 0.027 0.000
H65-H75 Diseases of middle ear and mastoid
0.973 0.027 0.000
Z47 Other orthopaedic follow-up care
0.973 0.027 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.973 0.027 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.971 0.029 0.000
H90-H95 Other disorders of ear
0.969 0.031 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.969 0.031 0.000
E11 Non-insulin-dependent diabetes mellitus
0.965 0.035 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.961 0.039 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.960 0.040 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.957 0.043 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.952 0.048 0.000
Chapter XX External causes of morbidity and mortality
0.951 0.049 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.950 0.050 0.000
M05-M14 Inflammatory polyarthropathies
0.950 0.050 0.000
I20-I25 Ischaemic heart diseases
0.949 0.051 0.000
M65-M68 Disorders of synovium and tendon
0.946 0.054 0.000
M50-M54 Other dorsopathies
0.945 0.055 0.000
G90-G99 Other disorders of the nervous system
0.941 0.059 0.000
C15-C26 Malignant neoplasms of digestive organs
0.940 0.060 0.000
E11.9 Without complications
0.937 0.063 0.000
I25 Chronic ischaemic heart disease
0.937 0.063 0.000
Z53.8 Procedure not carried out for other reasons
0.934 0.066 0.000
M06 Other rheumatoid arthritis
0.924 0.076 0.000
M54 Dorsalgia
0.924 0.076 0.000
Z48 Other surgical follow-up care
0.923 0.077 0.000
M65 Synovitis and tenosynovitis
0.920 0.080 0.000
Z50.1 Other physical therapy
0.919 0.081 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.918 0.082 0.000
H92 Otalgia and effusion of ear
0.915 0.085 0.000
M54.5 Low back pain
0.914 0.086 0.000
C18 Malignant neoplasm of colon
0.908 0.092 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.906 0.094 0.000
B35-B49 Mycoses
0.906 0.094 0.000
O48 Prolonged pregnancy
0.905 0.095 0.000
M06.9 Rheumatoid arthritis, unspecified
0.905 0.095 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.905 0.095 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.904 0.096 0.000
A30-A49 Other bacterial diseases
0.901 0.099 0.000
M54.59 Low back pain (Site unspecified)
0.900 0.100 0.000
I25.1 Atherosclerotic heart disease
0.899 0.101 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.895 0.105 0.000
Z13 Special screening examination for other diseases and disorders
0.890 0.110 0.000
Z53.9 Procedure not carried out, unspecified reason
0.886 0.114 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.886 0.114 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.885 0.115 0.000
G93 Other disorders of brain
0.883 0.117 0.000
E20-E35 Disorders of other endocrine glands
0.882 0.118 0.000
T93 Sequelae of injuries of lower limb
0.882 0.118 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.881 0.119 0.000
H60-H62 Diseases of external ear
0.881 0.119 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.875 0.125 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.875 0.125 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.872 0.128 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.869 0.131 0.000
M80-M85 Disorders of bone density and structure
0.868 0.132 0.000
H90 Conductive and sensorineural hearing loss
0.864 0.136 0.000
Chapter XXII Codes for special purposes
0.863 0.137 0.000
G40-G47 Episodic and paroxysmal disorders
0.862 0.138 0.000
H72 Perforation of tympanic membrane
0.862 0.138 0.000
I05-I09 Chronic rheumatic heart diseases
0.858 0.142 0.000
T92 Sequelae of injuries of upper limb
0.855 0.145 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.852 0.148 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.852 0.148 0.000
O36 Maternal care for other known or suspected foetal problems
0.851 0.149 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.850 0.150 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.849 0.150 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.847 0.153 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.846 0.154 0.000
R03.1 Nonspecific low blood-pressure reading
0.844 0.156 0.000
E11.3 With ophthalmic complications
0.843 0.157 0.000
C18.0 Caecum
0.843 0.157 0.000
H65 Nonsuppurative otitis media
0.840 0.160 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.839 0.161 0.000
G20-G26 Extrapyramidal and movement disorders
0.838 0.162 0.000
C20 Malignant neoplasm of rectum
0.834 0.166 0.000
R04 Haemorrhage from respiratory passages
0.832 0.168 0.000
Z00.0 General medical examination
0.831 0.169 0.000
D00-D09 In situ neoplasms
0.831 0.169 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.828 0.172 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.826 0.174 0.000
T90 Sequelae of injuries of head
0.825 0.175 0.000
C64-C68 Malignant neoplasms of urinary tract
0.823 0.177 0.000
B95-B98 Bacterial, viral and other infectious agents
0.821 0.179 0.000
T86 Failure and rejection of transplanted organs and tissues
0.820 0.180 0.000
H92.1 Otorrhoea
0.820 0.180 0.000
O41 Other disorders of amniotic fluid and membranes
0.820 0.180 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.817 0.182 0.000
E11.4 With neurological complications
0.816 0.184 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.815 0.185 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.814 0.186 0.000
I20 Angina pectoris
0.813 0.187 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.813 0.187 0.000
Z48.0 Attention to surgical dressings and sutures
0.812 0.188 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.811 0.189 0.000
H92.0 Otalgia
0.809 0.191 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.809 0.191 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.809 0.191 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.808 0.192 0.000
R04.0 Epistaxis
0.808 0.192 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.807 0.193 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.806 0.194 0.000
C92 Myeloid leukaemia
0.802 0.198 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.798 0.202 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.796 0.204 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.794 0.206 0.000
C51-C58 Malignant neoplasms of female genital organs
0.794 0.206 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.792 0.208 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.792 0.208 0.000
G70-G73 Diseases of myoneural junction and muscle
0.792 0.208 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.792 0.208 0.000
A41 Other septicaemia
0.790 0.210 0.000
B37 Candidiasis
0.789 0.211 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.787 0.213 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.783 0.217 0.000
Chapter XIV Diseases of the genitourinary system
0.780 0.220 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.780 0.220 0.000
H71 Cholesteatoma of middle ear
0.777 0.223 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.777 0.223 0.000
Z48.9 Surgical follow-up care, unspecified
0.775 0.225 0.000
C18.2 Ascending colon
0.775 0.225 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.773 0.227 0.000
C21 Malignant neoplasm of anus and anal canal
0.772 0.228 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.772 0.228 0.000
D10-D36 Benign neoplasms
0.772 0.228 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.771 0.229 0.000
C91 Lymphoid leukaemia
0.771 0.229 0.000
Chapter XI Diseases of the digestive system
0.769 0.231 0.000
E50-E64 Other nutritional deficiencies
0.769 0.231 0.000
H66 Suppurative and unspecified otitis media
0.768 0.231 0.000
Z50.5 Speech therapy
0.768 0.232 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.767 0.233 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.766 0.234 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.766 0.234 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.766 0.234 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.766 0.234 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.765 0.235 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.764 0.236 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.763 0.236 0.000
H74 Other disorders of middle ear and mastoid
0.763 0.237 0.000
N17-N19 Renal failure
0.763 0.237 0.000
E11.1 With ketoacidosis
0.763 0.237 0.000
G93.6 Cerebral oedema
0.761 0.239 0.000
Z40 Prophylactic surgery
0.759 0.241 0.000
Z45 Adjustment and management of implanted device
0.758 0.242 0.000
M80 Osteoporosis with pathological fracture
0.757 0.243 0.000
N19 Unspecified renal failure
0.756 0.244 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.755 0.245 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.755 0.245 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.754 0.246 0.000
Z49 Care involving dialysis
0.753 0.246 0.000
D12.3 Transverse colon
0.753 0.247 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.752 0.248 0.000
G93.8 Other specified disorders of brain
0.751 0.248 0.000
Z47.8 Other specified orthopaedic follow-up care
0.751 0.249 0.000
M40-M43 Deforming dorsopathies
0.751 0.249 0.000
H60 Otitis externa
0.750 0.250 0.000
C81 Hodgkin's disease
0.750 0.250 0.000
O43 Placental disorders
0.750 0.250 0.000
Z12 Special screening examination for neoplasms
0.749 0.251 0.000
Z50.0 Cardiac rehabilitation
0.748 0.252 0.000
E65-E68 Obesity and other hyperalimentation
0.747 0.253 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.746 0.254 0.000
S20-S29 Injuries to the thorax
0.746 0.254 0.000
E13 Other specified diabetes mellitus
0.746 0.254 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.744 0.256 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.742 0.257 0.000
G30-G32 Other degenerative diseases of the nervous system
0.742 0.258 0.000
G91 Hydrocephalus
0.741 0.259 0.000
I20.9 Angina pectoris, unspecified
0.741 0.259 0.000
T91 Sequelae of injuries of neck and trunk
0.740 0.260 0.000
H69 Other disorders of Eustachian tube
0.739 0.261 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.739 0.261 0.000
T98 Sequelae of other and unspecified effects of external causes
0.738 0.262 0.000
G47 Sleep disorders
0.737 0.263 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.737 0.263 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.736 0.264 0.000
E27 Other disorders of adrenal gland
0.735 0.264 0.000
M00-M03 Infectious arthropathies
0.735 0.264 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.735 0.265 0.000
Z13.1 Special screening examination for diabetes mellitus
0.734 0.266 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.734 0.266 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.733 0.267 0.000
C18.3 Hepatic flexure
0.732 0.268 0.000
B44 Aspergillosis
0.731 0.269 0.000
O47 False labour
0.730 0.269 0.000
V20-V29 Motorcycle rider injured in transport accident
0.730 0.270 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.730 0.270 0.000
Z00.5 Examination of potential donor of organ and tissue
0.730 0.270 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.730 0.270 0.000
B35 Dermatophytosis
0.729 0.270 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.729 0.271 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.727 0.272 0.000
E07 Other disorders of thyroid
0.727 0.273 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.726 0.274 0.000
W20-W49 Exposure to inanimate mechanical forces
0.725 0.275 0.000
O60-O75 Complications of labour and delivery
0.725 0.275 0.000
O32.1 Maternal care for breech presentation
0.725 0.275 0.000
S10-S19 Injuries to the neck
0.724 0.276 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.723 0.277 0.000
H61 Other disorders of external ear
0.721 0.279 0.000
Z54 Convalescence
0.720 0.280 0.000
D03 Melanoma in situ
0.720 0.280 0.000
O36.6 Maternal care for excessive foetal growth
0.719 0.281 0.000
N10-N16 Renal tubulo-interstitial diseases
0.719 0.281 0.000
A40 Streptococcal septicaemia
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.716 0.284 0.000
Z44 Fitting and adjustment of external prosthetic device
0.716 0.284 0.000
B37.0 Candidal stomatitis
0.716 0.284 0.000
I30-I52 Other forms of heart disease
0.716 0.284 0.000
M91-M94 Chondropathies
0.715 0.285 0.000
C92.0 Acute myeloid leukaemia
0.715 0.285 0.000
K70-K77 Diseases of liver
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
H73 Other disorders of tympanic membrane
0.713 0.287 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.713 0.287 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.713 0.287 0.000
T79-T79 Certain early complications of trauma
0.712 0.288 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.712 0.288 0.000
E00 Congenital iodine-deficiency syndrome
0.712 0.288 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.712 0.288 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.712 0.288 0.000
C50-C50 Malignant neoplasm of breast
0.712 0.288 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.711 0.289 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.711 0.289 0.000
M60-M63 Disorders of muscles
0.711 0.289 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.711 0.289 0.000
A49 Bacterial infection of unspecified site
0.711 0.289 0.000
T33-T35 Frostbite
0.711 0.289 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.711 0.289 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.711 0.289 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.711 0.289 0.000
T00-T07 Injuries involving multiple body regions
0.711 0.289 0.000
I07 Rheumatic tricuspid valve diseases
0.711 0.289 0.000
M54.2 Cervicalgia
0.710 0.290 0.000
M54.50 Low back pain (Multiple sites in spine)
0.710 0.290 0.000
I74 Arterial embolism and thrombosis
0.710 0.290 0.000
E03.8 Other specified hypothyroidism
0.710 0.290 0.000
E03.5 Myxoedema coma
0.710 0.290 0.000
E03.4 Atrophy of thyroid (acquired)
0.710 0.290 0.000
E03.3 Postinfectious hypothyroidism
0.710 0.290 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.710 0.290 0.000
E03.1 Congenital hypothyroidism without goitre
0.710 0.290 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.710 0.290 0.000
R22.0 Localised swelling, mass and lump, head
0.710 0.290 0.000
S00-S09 Injuries to the head
0.709 0.291 0.000
U88 Agent resistant to multiple antibiotics
0.709 0.291 0.000
K12 Stomatitis and related lesions
0.708 0.292 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.708 0.292 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.708 0.292 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.708 0.292 0.000
K08 Other disorders of teeth and supporting structures
0.707 0.293 0.000
M13 Other arthritis
0.707 0.293 0.000
M84 Disorders of continuity of bone
0.707 0.293 0.000
E29 Testicular dysfunction
0.706 0.294 0.000
G03 Meningitis due to other and unspecified causes
0.706 0.294 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.706 0.294 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.705 0.295 0.000
B99-B99 Other infectious diseases
0.705 0.295 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.705 0.295 0.000
B65-B83 Helminthiases
0.705 0.295 0.000
B50-B64 Protozoal diseases
0.705 0.295 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.705 0.295 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.705 0.295 0.000
A75-A79 Rickettsioses
0.705 0.295 0.000
A70-A74 Other diseases caused by chlamydiae
0.705 0.295 0.000
A65-A69 Other spirochaetal diseases
0.705 0.295 0.000
A20-A28 Certain zoonotic bacterial diseases
0.705 0.295 0.000
A15-A19 Tuberculosis
0.705 0.295 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.704 0.296 0.000
B15-B19 Viral hepatitis
0.703 0.297 0.000
Z50.6 Orthoptic training
0.703 0.297 0.000
Z50.3 Drug rehabilitation
0.703 0.297 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.703 0.297 0.000
I00-I02 Acute rheumatic fever
0.702 0.298 0.000
T87 Complications peculiar to reattachment and amputation
0.702 0.298 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.701 0.299 0.000
G61 Inflammatory polyneuropathy
0.701 0.299 0.000
H90.0 Conductive hearing loss, bilateral
0.701 0.299 0.000
I10-I15 Hypertensive diseases
0.700 0.300 0.000
H91 Other hearing loss
0.700 0.300 0.000
T90.9 Sequelae of unspecified injury of head
0.700 0.300 0.000
T93.2 Sequelae of other fractures of lower limb
0.699 0.301 0.000
M86-M90 Other osteopathies
0.699 0.301 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.698 0.302 0.000
E12 Malnutrition-related diabetes mellitus
0.698 0.302 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.698 0.302 0.000
H70 Mastoiditis and related conditions
0.698 0.302 0.000
H68 Eustachian salpingitis and obstruction
0.698 0.302 0.000
H67 Otitis media in diseases classified elsewhere
0.698 0.302 0.000
Z47.9 Orthopaedic follow-up care, unspecified
0.698 0.302 0.000
C67 Malignant neoplasm of bladder
0.698 0.302 0.000
Z10 Routine general health check-up of defined subpopulation
0.697 0.303 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.697 0.303 0.000
H93 Other disorders of ear, not elsewhere classified
0.697 0.303 0.000
Chapter VII Diseases of the eye and adnexa
0.697 0.303 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.696 0.303 0.000
T95 Sequelae of burns, corrosions and frostbite
0.696 0.304 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.696 0.304 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.696 0.304 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.696 0.304 0.000
W00-W19 Falls
0.696 0.304 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.696 0.304 0.000
Z48.8 Other specified surgical follow-up care
0.695 0.304 0.000
O00-O08 Pregnancy with abortive outcome
0.695 0.305 0.000
C18.7 Sigmoid colon
0.695 0.305 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.695 0.305 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.695 0.305 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.695 0.305 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.695 0.305 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.695 0.305 0.000
O85-O92 Complications predominantly related to the puerperium
0.694 0.305 0.000
K04 Diseases of pulp and periapical tissues
0.694 0.306 0.000
M07 Psoriatic and enteropathic arthropathies
0.694 0.306 0.000
G25 Other extrapyramidal and movement disorders
0.694 0.306 0.000
B25-B34 Other viral diseases
0.693 0.307 0.000
E11.8 With unspecified complications
0.692 0.308 0.000
E11.7 With multiple complications
0.692 0.308 0.000
E11.6 With other specified complications
0.692 0.308 0.000
E11.0 With coma
0.692 0.308 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.692 0.308 0.000
I99 Other and unspecified disorders of circulatory system
0.692 0.308 0.000
S90-S99 Injuries to the ankle and foot
0.692 0.308 0.000
G41 Status epilepticus
0.691 0.309 0.000
Z43 Attention to artificial openings
0.691 0.309 0.000
R07 Pain in throat and chest
0.691 0.309 0.000
K09 Cysts of oral region, not elsewhere classified
0.691 0.309 0.000
I08 Multiple valve diseases
0.691 0.309 0.000
S50-S59 Injuries to the elbow and forearm
0.690 0.310 0.000
E11.5 With peripheral circulatory complications
0.690 0.310 0.000
G96 Other disorders of central nervous system
0.690 0.310 0.000
O45 Premature separation of placenta [abruptio placentae]
0.689 0.311 0.000
O44 Placenta praevia
0.689 0.311 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.689 0.311 0.000
O33 Maternal care for known or suspected disproportion
0.689 0.311 0.000
O31 Complications specific to multiple gestation
0.689 0.311 0.000
O40 Polyhydramnios
0.689 0.311 0.000
C91.1 Chronic lymphocytic leukaemia
0.689 0.311 0.000
S70-S79 Injuries to the hip and thigh
0.689 0.311 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.689 0.311 0.000
O36.5 Maternal care for poor foetal growth
0.688 0.312 0.000
Z29 Need for other prophylactic measures
0.688 0.312 0.000
C18.5 Splenic flexure
0.688 0.312 0.000
D12.0 Caecum
0.687 0.313 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.687 0.313 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.686 0.314 0.000
N13 Obstructive and reflux uropathy
0.686 0.314 0.000
Z41 Procedures for purposes other than remedying health state
0.685 0.315 0.000
R06 Abnormalities of breathing
0.685 0.315 0.000
A80-A89 Viral infections of the central nervous system
0.685 0.315 0.000
O41.8 Other specified disorders of amniotic fluid and membranes
0.684 0.316 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.684 0.316 0.000
M54.1 Radiculopathy
0.684 0.316 0.000
E40-E46 Malnutrition
0.683 0.317 0.000
T92.0 Sequelae of open wound of upper limb
0.683 0.317 0.000
M54.56 Low back pain (Lumbar region)
0.683 0.317 0.000
I78 Diseases of capillaries
0.683 0.317 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.683 0.317 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.683 0.317 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.683 0.317 0.000
Y35-Y36 Legal intervention and operations of war
0.682 0.318 0.000
Y10-Y34 Event of undetermined intent
0.682 0.318 0.000
Y00-Y09 Assault
0.682 0.318 0.000
X85-X99 Assault
0.682 0.318 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.682 0.318 0.000
X50-X57 Overexertion, travel and privation
0.682 0.318 0.000
X30-X39 Exposure to forces of nature
0.682 0.318 0.000
X20-X29 Contact with venomous animals and plants
0.682 0.318 0.000
X10-X19 Contact with heat and hot substances
0.682 0.318 0.000
X00-X09 Exposure to smoke, fire and flames
0.682 0.318 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.682 0.318 0.000
W75-W84 Other accidental threats to breathing
0.682 0.318 0.000
W65-W74 Accidental drowning and submersion
0.682 0.318 0.000
W50-W64 Exposure to animate mechanical forces
0.682 0.318 0.000
V98-V99 Other and unspecified transport accidents
0.682 0.318 0.000
V95-V97 Air and space transport accidents
0.682 0.318 0.000
V90-V94 Water transport accidents
0.682 0.318 0.000
V80-V89 Other land transport accidents
0.682 0.318 0.000
V70-V79 Bus occupant injured in transport accident
0.682 0.318 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.682 0.318 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.682 0.318 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.682 0.318 0.000
V01-V09 Pedestrian injured in transport accident
0.682 0.318 0.000
G43 Migraine
0.682 0.318 0.000
E26 Hyperaldosteronism
0.681 0.318 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.681 0.319 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.681 0.319 0.000
M14 Arthropathies in other diseases classified elsewhere
0.681 0.319 0.000
M12 Other specific arthropathies
0.681 0.319 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.681 0.319 0.000
M08 Juvenile arthritis
0.681 0.319 0.000
I23 Certain current complications following acute myocardial infarction
0.681 0.319 0.000
G93.3 Postviral fatigue syndrome
0.681 0.319 0.000
I20.8 Other forms of angina pectoris
0.680 0.320 0.000
B00 Herpesviral [herpes simplex] infections
0.680 0.320 0.000
Z45.2 Adjustment and management of vascular access device
0.680 0.320 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.678 0.322 0.000
M66 Spontaneous rupture of synovium and tendon
0.678 0.322 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.678 0.322 0.000
M53 Other dorsopathies, not elsewhere classified
0.677 0.322 0.000
I25.5 Ischaemic cardiomyopathy
0.676 0.324 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.675 0.325 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.675 0.325 0.000
G90 Disorders of autonomic nervous system
0.675 0.325 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.675 0.325 0.000
G92 Toxic encephalopathy
0.675 0.325 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.674 0.326 0.000
C17 Malignant neoplasm of small intestine
0.674 0.326 0.000
C23 Malignant neoplasm of gallbladder
0.674 0.326 0.000
M06.0 Seronegative rheumatoid arthritis
0.673 0.327 0.000
M10 Gout
0.673 0.327 0.000
Z50.8 Care involving use of rehabilitation procedures
0.673 0.327 0.000
I25.6 Silent myocardial ischaemia
0.672 0.328 0.000
I25.4 Coronary artery aneurysm
0.672 0.328 0.000
I25.3 Aneurysm of heart
0.672 0.328 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.672 0.328 0.000
E65 Localised adiposity
0.671 0.329 0.000
H90.5 Sensorineural hearing loss, unspecified
0.670 0.330 0.000
H65.4 Other chronic nonsuppurative otitis media
0.670 0.330 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.670 0.330 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.669 0.331 0.000
Y86 Sequelae of other accidents
0.668 0.331 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.668 0.332 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.667 0.333 0.000
M51 Other intervertebral disk disorders
0.666 0.334 0.000
R22.1 Localised swelling, mass and lump, neck
0.666 0.334 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.666 0.334 0.000
E23 Hypofunction and other disorders of pituitary gland
0.665 0.335 0.000
D06 Carcinoma in situ of cervix uteri
0.665 0.335 0.000
G95 Other diseases of spinal cord
0.664 0.336 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.664 0.336 0.000
K12.1 Other forms of stomatitis
0.663 0.337 0.000
M06.8 Other specified rheumatoid arthritis
0.663 0.337 0.000
M06.4 Inflammatory polyarthropathy
0.663 0.337 0.000
M06.3 Rheumatoid nodule
0.663 0.337 0.000
M06.2 Rheumatoid bursitis
0.663 0.337 0.000
M06.1 Adult-onset Still's disease
0.663 0.337 0.000
M54.8 Other dorsalgia
0.662 0.338 0.000
M54.0 Panniculitis affecting regions of neck and back
0.662 0.338 0.000
Z50.2 Alcohol rehabilitation
0.662 0.338 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.662 0.338 0.000
L03 Cellulitis
0.661 0.339 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.660 0.340 0.000
R02 Gangrene, not elsewhere classified
0.660 0.340 0.000
I22 Subsequent myocardial infarction
0.660 0.340 0.000
M65.8 Other synovitis and tenosynovitis
0.660 0.340 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.660 0.340 0.000
M65.2 Calcific tendinitis
0.660 0.340 0.000
M65.1 Other infective (teno)synovitis
0.660 0.340 0.000
M65.0 Abscess of tendon sheath
0.660 0.340 0.000
M45-M49 Spondylopathies
0.660 0.340 0.000
M11 Other crystal arthropathies
0.659 0.341 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.659 0.341 0.000
T92.1 Sequelae of fracture of arm
0.659 0.341 0.000
T82.1 Mechanical complication of cardiac electronic device
0.658 0.342 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.658 0.342 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.658 0.342 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.658 0.342 0.000
T82.3 Mechanical complication of other vascular grafts
0.658 0.342 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.658 0.342 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.658 0.342 0.000
T31 Burns classified according to extent of body surface involved
0.657 0.343 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.657 0.343 0.000
E11.2 With renal complications
0.657 0.343 0.000
O36.8 Maternal care for other specified foetal problems
0.657 0.343 0.000
H92.2 Otorrhagia
0.656 0.344 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.656 0.344 0.000
M54.55 Low back pain (Thoracolumbar region)
0.656 0.344 0.000
M54.54 Low back pain-Thoracic
0.656 0.344 0.000
M54.53 Low back pain-Cervicothoracic
0.656 0.344 0.000
M54.52 Low back pain-Cervical
0.656 0.344 0.000
M54.51 Low back pain-Occipit-atl-axl
0.656 0.344 0.000
M85 Other disorders of bone density and structure
0.655 0.345 0.000
G44 Other headache syndromes
0.655 0.345 0.000
K04.7 Periapical abscess without sinus
0.655 0.345 0.000
H65.3 Chronic mucoid otitis media
0.654 0.346 0.000
T86.0 Bone-marrow transplant rejection
0.654 0.346 0.000
C18.9 Colon, unspecified
0.654 0.346 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.654 0.346 0.000
L85 Other epidermal thickening
0.654 0.346 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.652 0.348 0.000
M54.6 Pain in thoracic spine
0.652 0.348 0.000
C18.8 Overlapping lesion of colon
0.651 0.349 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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