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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7275460
log Bayes Factor = 9.35732
Chromosome 21   position 41,447,058  (GRCh37) Explore rs7275460 on Ensembl!
Variant rs7275460 is part of Cluster X0052

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.995 0.005 0.000
H53-H54 Visual disturbances and blindness
0.994 0.006 0.000
Chapter XX External causes of morbidity and mortality
0.994 0.006 0.000
E10-E14 Diabetes mellitus
0.994 0.006 0.000
W00-W19 Falls
0.993 0.007 0.000
W19 Unspecified fall
0.992 0.008 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.990 0.010 0.000
E65-E68 Obesity and other hyperalimentation
0.990 0.010 0.000
G90-G99 Other disorders of the nervous system
0.988 0.012 0.000
R94 Abnormal results of function studies
0.988 0.012 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.987 0.013 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.984 0.016 0.000
Chapter VIII Diseases of the ear and mastoid process
0.983 0.017 0.000
H53 Visual disturbances
0.981 0.019 0.000
E10 Insulin-dependent diabetes mellitus
0.980 0.020 0.000
E66 Obesity
0.978 0.022 0.000
R94.5 Abnormal results of liver function studies
0.978 0.022 0.000
H53.2 Diplopia
0.971 0.029 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.971 0.029 0.000
W19.2 School, other institution and public administrative area
0.964 0.036 0.000
E66.9 Obesity, unspecified
0.963 0.037 0.000
R94.3 Abnormal results of cardiovascular function studies
0.961 0.039 0.000
G95 Other diseases of spinal cord
0.961 0.039 0.000
O36 Maternal care for other known or suspected foetal problems
0.959 0.041 0.000
W19.9 Unspecified place
0.956 0.044 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.954 0.046 0.000
H65-H75 Diseases of middle ear and mastoid
0.944 0.056 0.000
R29.6 Tendency to fall, not elsewhere classified
0.944 0.056 0.000
E11 Non-insulin-dependent diabetes mellitus
0.940 0.060 0.000
G81 Hemiplegia
0.938 0.062 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.937 0.063 0.000
H54 Blindness and low vision
0.937 0.063 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.934 0.066 0.000
G30-G32 Other degenerative diseases of the nervous system
0.932 0.068 0.000
G95.8 Other specified diseases of spinal cord
0.930 0.070 0.000
S00-S09 Injuries to the head
0.925 0.075 0.000
Chapter XXI Factors influencing health status and contact with health services
0.919 0.081 0.000
H10-H13 Disorders of conjunctiva
0.915 0.085 0.000
G81.9 Hemiplegia, unspecified
0.915 0.085 0.000
S60-S69 Injuries to the wrist and hand
0.915 0.085 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.914 0.086 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.898 0.102 0.000
E10.1 With ketoacidosis
0.898 0.102 0.000
H53.8 Other visual disturbances
0.894 0.106 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.894 0.106 0.000
R25 Abnormal involuntary movements
0.893 0.107 0.000
E10.9 Without complications
0.889 0.111 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.887 0.113 0.000
G70-G73 Diseases of myoneural junction and muscle
0.884 0.116 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.883 0.117 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.882 0.117 0.000
O41 Other disorders of amniotic fluid and membranes
0.879 0.121 0.000
W19.4 Street and highway
0.879 0.121 0.000
H80-H83 Diseases of inner ear
0.877 0.123 0.000
H55-H59 Other disorders of eye and adnexa
0.869 0.131 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.868 0.132 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.866 0.134 0.000
H54.4 Blindness, one eye
0.865 0.135 0.000
R26 Abnormalities of gait and mobility
0.865 0.135 0.000
O36.8 Maternal care for other specified foetal problems
0.865 0.135 0.000
Z35 Supervision of high-risk pregnancy
0.863 0.137 0.000
S62 Fracture at wrist and hand level
0.862 0.138 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.861 0.139 0.000
H60-H62 Diseases of external ear
0.860 0.140 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.860 0.140 0.000
E65 Localised adiposity
0.859 0.141 0.000
T87 Complications peculiar to reattachment and amputation
0.856 0.144 0.000
O36.5 Maternal care for poor foetal growth
0.856 0.144 0.000
E11.4 With neurological complications
0.856 0.144 0.000
O45 Premature separation of placenta [abruptio placentae]
0.855 0.145 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.852 0.148 0.000
H72 Perforation of tympanic membrane
0.850 0.150 0.000
S05 Injury of eye and orbit
0.842 0.158 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.841 0.159 0.000
S64 Injury of nerves at wrist and hand level
0.841 0.159 0.000
Z31 Procreative management
0.837 0.163 0.000
G30 Alzheimer's disease
0.834 0.166 0.000
O48 Prolonged pregnancy
0.833 0.167 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.832 0.168 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.830 0.170 0.000
H11 Other disorders of conjunctiva
0.829 0.171 0.000
E66.8 Other obesity
0.824 0.176 0.000
G95.9 Disease of spinal cord, unspecified
0.820 0.180 0.000
S62.6 Fracture of other finger
0.818 0.182 0.000
H66 Suppurative and unspecified otitis media
0.817 0.183 0.000
W19.1 Residential institution
0.816 0.184 0.000
M86-M90 Other osteopathies
0.815 0.185 0.000
W20-W49 Exposure to inanimate mechanical forces
0.813 0.187 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.813 0.187 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.810 0.190 0.000
O85-O92 Complications predominantly related to the puerperium
0.810 0.190 0.000
O46.9 Antepartum haemorrhage, unspecified
0.810 0.190 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.809 0.191 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.808 0.192 0.000
T17 Foreign body in respiratory tract
0.805 0.195 0.000
Z35.5 Supervision of elderly primigravida
0.804 0.196 0.000
O20 Haemorrhage in early pregnancy
0.804 0.196 0.000
S10-S19 Injuries to the neck
0.804 0.196 0.000
H83 Other diseases of inner ear
0.803 0.197 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.802 0.198 0.000
E11.5 With peripheral circulatory complications
0.800 0.199 0.000
S06 Intracranial injury
0.800 0.200 0.000
Z39 Postpartum care and examination
0.797 0.203 0.000
W13 Fall from, out of or through building or structure
0.796 0.204 0.000
W08 Fall involving other furniture
0.796 0.204 0.000
H74 Other disorders of middle ear and mastoid
0.795 0.205 0.000
S90-S99 Injuries to the ankle and foot
0.793 0.207 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.793 0.207 0.000
Z57 Occupational exposure to risk-factors
0.792 0.208 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.790 0.210 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.790 0.210 0.000
M65-M68 Disorders of synovium and tendon
0.790 0.210 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.788 0.212 0.000
M05-M14 Inflammatory polyarthropathies
0.787 0.213 0.000
X60-X84 Intentional self-harm
0.785 0.215 0.000
R50-R69 General symptoms and signs
0.785 0.215 0.000
Y00-Y09 Assault
0.784 0.216 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.784 0.216 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.783 0.217 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.782 0.218 0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation
0.782 0.218 0.000
E10.0 With coma
0.781 0.219 0.000
H57 Other disorders of eye and adnexa
0.780 0.220 0.000
G82 Paraplegia and tetraplegia
0.779 0.220 0.000
S62.60 Fracture of other finger (closed)
0.779 0.221 0.000
W17 Other fall from one level to another
0.776 0.224 0.000
T00-T07 Injuries involving multiple body regions
0.775 0.225 0.000
O41.0 Oligohydramnios
0.774 0.226 0.000
R25.1 Tremor, unspecified
0.774 0.226 0.000
G83 Other paralytic syndromes
0.774 0.226 0.000
H54.7 Unspecified visual loss
0.774 0.226 0.000
V20-V29 Motorcycle rider injured in transport accident
0.773 0.227 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.771 0.229 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.770 0.230 0.000
R94.4 Abnormal results of kidney function studies
0.770 0.230 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.770 0.230 0.000
Z37 Outcome of delivery
0.769 0.231 0.000
T91 Sequelae of injuries of neck and trunk
0.767 0.233 0.000
O60-O75 Complications of labour and delivery
0.766 0.234 0.000
E10.6 With other specified complications
0.765 0.235 0.000
O44 Placenta praevia
0.764 0.236 0.000
T87.6 Other and unspecified complications of amputation stump
0.764 0.236 0.000
G90 Disorders of autonomic nervous system
0.764 0.236 0.000
H72.8 Other perforations of tympanic membrane
0.763 0.237 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.761 0.239 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.760 0.240 0.000
R94.6 Abnormal results of thyroid function studies
0.760 0.240 0.000
E11.6 With other specified complications
0.759 0.241 0.000
H72.0 Central perforation of tympanic membrane
0.759 0.241 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.756 0.244 0.000
O45.9 Premature separation of placenta, unspecified
0.754 0.246 0.000
E11.9 Without complications
0.752 0.248 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.751 0.249 0.000
H83.0 Labyrinthitis
0.750 0.250 0.000
Z35.0 Supervision of pregnancy with history of infertility
0.749 0.251 0.000
E10.8 With unspecified complications
0.748 0.252 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.747 0.253 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.747 0.253 0.000
E10.4 With neurological complications
0.747 0.253 0.000
O24 Diabetes mellitus in pregnancy
0.747 0.253 0.000
G30.9 Alzheimer's disease, unspecified
0.746 0.254 0.000
G20-G26 Extrapyramidal and movement disorders
0.746 0.254 0.000
S65 Injury of blood vessels at wrist and hand level
0.745 0.255 0.000
H54.0 Blindness, both eyes
0.743 0.257 0.000
M89 Other disorders of bone
0.742 0.258 0.000
M10 Gout
0.741 0.259 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.741 0.259 0.000
S64.1 Injury of median nerve at wrist and hand level
0.741 0.259 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.740 0.260 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.740 0.260 0.000
H61 Other disorders of external ear
0.739 0.261 0.000
H10 Conjunctivitis
0.738 0.262 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.738 0.262 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.737 0.263 0.000
S02 Fracture of skull and facial bones
0.736 0.264 0.000
H65 Nonsuppurative otitis media
0.735 0.265 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.735 0.265 0.000
T86 Failure and rejection of transplanted organs and tissues
0.735 0.265 0.000
W07 Fall involving chair
0.734 0.266 0.000
T79-T79 Certain early complications of trauma
0.733 0.267 0.000
H04 Disorders of lachrymal system
0.733 0.267 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.733 0.267 0.000
X20-X29 Contact with venomous animals and plants
0.733 0.267 0.000
M67 Other disorders of synovium and tendon
0.732 0.268 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.732 0.268 0.000
H18 Other disorders of cornea
0.730 0.270 0.000
R52 Pain, not elsewhere classified
0.730 0.270 0.000
W10 Fall on and from stairs and steps
0.730 0.270 0.000
E10.3 With ophthalmic complications
0.730 0.270 0.000
H49 Paralytic strabismus
0.730 0.270 0.000
M40-M43 Deforming dorsopathies
0.729 0.271 0.000
Z36 Antenatal screening
0.727 0.273 0.000
G71 Primary disorders of muscles
0.727 0.273 0.000
Z76 Persons encountering health services in other circumstances
0.727 0.273 0.000
H66.9 Otitis media, unspecified
0.724 0.276 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.724 0.276 0.000
G72 Other myopathies
0.724 0.276 0.000
H53.4 Visual field defects
0.723 0.277 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.722 0.278 0.000
R59 Enlarged lymph nodes
0.722 0.278 0.000
S31 Open wound of abdomen, lower back and pelvis
0.719 0.280 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.719 0.281 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.719 0.281 0.000
O80-O84 Delivery
0.718 0.282 0.000
O36.4 Maternal care for intra-uterine death
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R63 Symptoms and signs concerning food and fluid intake
0.716 0.284 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.716 0.284 0.000
Z37.0 Single live birth
0.715 0.285 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.715 0.285 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
G96 Other disorders of central nervous system
0.714 0.286 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.714 0.286 0.000
O33 Maternal care for known or suspected disproportion
0.714 0.286 0.000
O31 Complications specific to multiple gestation
0.714 0.286 0.000
O34.3 Maternal care for cervical incompetence
0.714 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.713 0.286 0.000
G95.0 Syringomyelia and syringobulbia
0.713 0.287 0.000
Y35-Y36 Legal intervention and operations of war
0.712 0.288 0.000
Y10-Y34 Event of undetermined intent
0.712 0.288 0.000
X85-X99 Assault
0.712 0.288 0.000
X30-X39 Exposure to forces of nature
0.712 0.288 0.000
X10-X19 Contact with heat and hot substances
0.712 0.288 0.000
X00-X09 Exposure to smoke, fire and flames
0.712 0.288 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.712 0.288 0.000
W75-W84 Other accidental threats to breathing
0.712 0.288 0.000
W65-W74 Accidental drowning and submersion
0.712 0.288 0.000
V98-V99 Other and unspecified transport accidents
0.712 0.288 0.000
V95-V97 Air and space transport accidents
0.712 0.288 0.000
V90-V94 Water transport accidents
0.712 0.288 0.000
V70-V79 Bus occupant injured in transport accident
0.712 0.288 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.712 0.288 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.712 0.288 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.712 0.288 0.000
V01-V09 Pedestrian injured in transport accident
0.712 0.288 0.000
E12 Malnutrition-related diabetes mellitus
0.712 0.288 0.000
T17.2 Foreign body in pharynx
0.712 0.288 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.712 0.288 0.000
W15 Fall from cliff
0.712 0.288 0.000
W14 Fall from tree
0.712 0.288 0.000
W12 Fall on and from scaffolding
0.712 0.288 0.000
W11 Fall on and from ladder
0.712 0.288 0.000
W09 Fall involving playground equipment
0.712 0.288 0.000
W05 Fall involving wheelchair
0.712 0.288 0.000
W04 Fall while being carried or supported by other persons
0.712 0.288 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.712 0.288 0.000
W00 Fall on same level involving ice and snow
0.712 0.288 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.711 0.288 0.000
W19.8 Other specified place
0.711 0.289 0.000
W19.5 Trade and service area
0.711 0.289 0.000
W19.0 Home
0.711 0.289 0.000
W19.7 Farm
0.711 0.289 0.000
W19.6 Industrial and construction area
0.711 0.289 0.000
S60 Superficial injury of wrist and hand
0.711 0.289 0.000
W50-W64 Exposure to animate mechanical forces
0.710 0.290 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.710 0.290 0.000
E13 Other specified diabetes mellitus
0.710 0.290 0.000
E67 Other hyperalimentation
0.709 0.290 0.000
E68 Sequelae of hyperalimentation
0.709 0.290 0.000
O34.1 Maternal care for tumour of corpus uteri
0.709 0.291 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.709 0.291 0.000
E10.5 With peripheral circulatory complications
0.709 0.291 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.709 0.291 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.709 0.291 0.000
G92 Toxic encephalopathy
0.709 0.291 0.000
S09 Other and unspecified injuries of head
0.709 0.291 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.708 0.292 0.000
R94.7 Abnormal results of other endocrine function studies
0.708 0.292 0.000
R94.2 Abnormal results of pulmonary function studies
0.708 0.292 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.708 0.292 0.000
R94.0 Abnormal results of function studies of central nervous system
0.708 0.292 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.708 0.292 0.000
S05.1 Contusion of eyeball and orbital tissues
0.706 0.294 0.000
H20 Iridocyclitis
0.706 0.294 0.000
X50-X57 Overexertion, travel and privation
0.705 0.295 0.000
H53.6 Night blindness
0.703 0.297 0.000
H53.5 Colour vision deficiencies
0.703 0.297 0.000
H53.3 Other disorders of binocular vision
0.703 0.297 0.000
V80-V89 Other land transport accidents
0.703 0.297 0.000
E10.7 With multiple complications
0.703 0.297 0.000
Z34 Supervision of normal pregnancy
0.703 0.297 0.000
E14 Unspecified diabetes mellitus
0.703 0.297 0.000
Z57.2 Occupational exposure to dust
0.702 0.298 0.000
T87.3 Neuroma of amputation stump
0.701 0.299 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.701 0.299 0.000
E66.1 Drug-induced obesity
0.701 0.299 0.000
E66.0 Obesity due to excess calories
0.701 0.299 0.000
S01 Open wound of head
0.701 0.299 0.000
R60 Oedema, not elsewhere classified
0.701 0.299 0.000
O21 Excessive vomiting in pregnancy
0.700 0.300 0.000
M10.9 Gout, unspecified
0.700 0.300 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.699 0.301 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.699 0.301 0.000
E10.2 With renal complications
0.698 0.302 0.000
H73 Other disorders of tympanic membrane
0.698 0.302 0.000
H57.1 Ocular pain
0.698 0.302 0.000
S11 Open wound of neck
0.696 0.304 0.000
R59.1 Generalised enlarged lymph nodes
0.696 0.304 0.000
W19.3 Sports and athletics area
0.693 0.307 0.000
S62.7 Multiple fractures of fingers
0.693 0.307 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.692 0.308 0.000
S69 Other and unspecified injuries of wrist and hand
0.691 0.309 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.691 0.309 0.000
E40-E46 Malnutrition
0.690 0.310 0.000
H04.1 Other disorders of lachrymal gland
0.690 0.310 0.000
G95.1 Vascular myelopathies
0.689 0.311 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.687 0.312 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.687 0.312 0.000
O36.2 Maternal care for hydrops foetalis
0.687 0.312 0.000
O36.1 Maternal care for other isoimmunisation
0.687 0.312 0.000
M45-M49 Spondylopathies
0.687 0.313 0.000
H70 Mastoiditis and related conditions
0.685 0.315 0.000
M91-M94 Chondropathies
0.685 0.315 0.000
M80-M85 Disorders of bone density and structure
0.685 0.315 0.000
M00-M03 Infectious arthropathies
0.685 0.315 0.000
T18 Foreign body in alimentary tract
0.684 0.316 0.000
S67 Crushing injury of wrist and hand
0.684 0.316 0.000
R29.4 Clicking hip
0.684 0.316 0.000
R29.3 Abnormal posture
0.684 0.316 0.000
R29.2 Abnormal reflex
0.684 0.316 0.000
R29.1 Meningismus
0.684 0.316 0.000
R29.0 Tetany
0.684 0.316 0.000
H60 Otitis externa
0.684 0.316 0.000
R27 Other lack of coordination
0.684 0.316 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.684 0.316 0.000
H81 Disorders of vestibular function
0.682 0.318 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.681 0.319 0.000
O41.8 Other specified disorders of amniotic fluid and membranes
0.680 0.320 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.680 0.320 0.000
R52.0 Acute pain
0.679 0.321 0.000
V40-V49 Car occupant injured in transport accident
0.679 0.321 0.000
Z39.0 Care and examination immediately after delivery
0.679 0.321 0.000
G70 Myasthenia gravis and other myoneural disorders
0.678 0.322 0.000
W18 Other fall on same level
0.678 0.322 0.000
S02.3 Fracture of orbital floor
0.678 0.322 0.000
R80 Isolated proteinuria
0.678 0.322 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.677 0.323 0.000
H68 Eustachian salpingitis and obstruction
0.677 0.323 0.000
H67 Otitis media in diseases classified elsewhere
0.677 0.323 0.000
H11.9 Disorder of conjunctiva, unspecified
0.676 0.324 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.676 0.324 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.676 0.324 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.675 0.325 0.000
O30 Multiple gestation
0.674 0.325 0.000
E11.8 With unspecified complications
0.674 0.326 0.000
E11.7 With multiple complications
0.674 0.326 0.000
O40 Polyhydramnios
0.673 0.327 0.000
M86 Osteomyelitis
0.673 0.327 0.000
H11.0 Pterygium
0.673 0.327 0.000
G81.1 Spastic hemiplegia
0.673 0.327 0.000
G81.0 Flaccid hemiplegia
0.673 0.327 0.000
S06.5 Traumatic subdural haemorrhage
0.673 0.327 0.000
O29 Complications of anaesthesia during pregnancy
0.672 0.328 0.000
O22 Venous complications in pregnancy
0.672 0.328 0.000
O25 Malnutrition in pregnancy
0.672 0.328 0.000
H54.6 Unqualified visual loss, one eye
0.672 0.328 0.000
H54.5 Low vision, one eye
0.672 0.328 0.000
H54.3 Unqualified visual loss, both eyes
0.672 0.328 0.000
H54.2 Low vision, both eyes
0.672 0.328 0.000
H54.1 Blindness, one eye, low vision, other eye
0.672 0.328 0.000
W44 Foreign body entering into or through eye or natural orifice
0.671 0.329 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.670 0.330 0.000
G93 Other disorders of brain
0.670 0.330 0.000
O28 Abnormal findings on antenatal screening of mother
0.669 0.331 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.668 0.332 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.668 0.332 0.000
R45 Symptoms and signs involving emotional state
0.668 0.332 0.000
M67.8 Other specified disorders of synovium and tendon
0.667 0.333 0.000
Z30 Contraceptive management
0.666 0.334 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.663 0.337 0.000
S08 Traumatic amputation of part of head
0.663 0.337 0.000
S07 Crushing injury of head
0.663 0.337 0.000
S04 Injury of cranial nerves
0.663 0.337 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.663 0.337 0.000
H11.3 Conjunctival haemorrhage
0.662 0.338 0.000
R25.3 Fasciculation
0.661 0.339 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.661 0.339 0.000
O90 Complications of the puerperium, not elsewhere classified
0.661 0.339 0.000
O47 False labour
0.660 0.340 0.000
Z57.5 Occupational exposure to toxic agents in other industries
0.660 0.340 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.658 0.342 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.658 0.342 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.657 0.343 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.657 0.343 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.656 0.344 0.000
E11.0 With coma
0.656 0.344 0.000
W13.9 Unspecified place
0.656 0.344 0.000
Z38 Liveborn infants according to place of birth
0.655 0.345 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.655 0.345 0.000
W08.0 Home
0.655 0.345 0.000
H16 Keratitis
0.654 0.346 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.654 0.346 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.652 0.347 0.000
O26.8 Other specified pregnancy-related conditions
0.652 0.348 0.000
G97.0 Cerebrospinal fluid leak from spinal puncture
0.652 0.348 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.652 0.348 0.000
Z64 Problems related to certain psychosocial circumstances
0.651 0.349 0.000
M60-M63 Disorders of muscles
0.651 0.349 0.000
T17.8 Foreign body in other and multiple parts of respiratory tract
0.650 0.350 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.649 0.351 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.649 0.351 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.649 0.351 0.000
S92 Fracture of foot, except ankle
0.649 0.351 0.000
Z76.9 Persons encountering health services in unspecified circumstances
0.648 0.351 0.000
H02 Other disorders of eyelid
0.648 0.352 0.000
G30.0 Alzheimer's disease with early onset
0.647 0.353 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.646 0.354 0.000
H49.2 Sixth [abducent] nerve palsy
0.646 0.354 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.645 0.354 0.000
M43 Other deforming dorsopathies
0.645 0.355 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.644 0.356 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.644 0.356 0.000
O34.6 Maternal care for abnormality of vagina
0.644 0.356 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.644 0.356 0.000
O34.4 Maternal care for other abnormalities of cervix
0.644 0.356 0.000
O34.0 Maternal care for congenital malformation of uterus
0.644 0.356 0.000
T91.1 Sequelae of fracture of spine
0.644 0.356 0.000
O23 Infections of genito-urinary tract in pregnancy
0.643 0.357 0.000
H74.0 Tympanosclerosis
0.643 0.357 0.000
Z57.3 Occupational exposure to other air contaminants
0.643 0.357 0.000
G31.8 Other specified degenerative diseases of nervous system
0.641 0.359 0.000
T19 Foreign body in genito-urinary tract
0.641 0.359 0.000
T15 Foreign body on external eye
0.641 0.359 0.000
T16 Foreign body in ear
0.641 0.359 0.000
R25.0 Abnormal head movements
0.640 0.359 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.640 0.360 0.000
E11.3 With ophthalmic complications
0.640 0.360 0.000
Z35.8 Supervision of other high-risk pregnancies
0.640 0.360 0.000
T92 Sequelae of injuries of upper limb
0.640 0.360 0.000
R57 Shock, not elsewhere classified
0.639 0.360 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.639 0.361 0.000
R46 Symptoms and signs involving appearance and behaviour
0.639 0.361 0.000
Z32 Pregnancy examination and test
0.638 0.361 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.639 0.361 0.000
E11.1 With ketoacidosis
0.638 0.362 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.638 0.362 0.000
T90 Sequelae of injuries of head
0.638 0.362 0.000
M05 Seropositive rheumatoid arthritis
0.638 0.362 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.637 0.363 0.000
S02.30 Fracture of orbital floor (closed)
0.637 0.363 0.000
G94.2 Hydrocephalus in other diseases classified elsewhere
0.636 0.363 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.636 0.364 0.000
O46.8 Other antepartum haemorrhage
0.636 0.364 0.000
O46.0 Antepartum haemorrhage with coagulation defect
0.636 0.364 0.000
R81 Glycosuria
0.636 0.364 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.635 0.364 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.635 0.365 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.635 0.365 0.000
R25.2 Cramp and spasm
0.634 0.366 0.000
Y04 Assault by bodily force
0.634 0.366 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.634 0.366 0.000
G83.4 Cauda equina syndrome
0.633 0.367 0.000
H40-H42 Glaucoma
0.632 0.368 0.000
S62.61 Fracture of other finger (open)
0.632 0.368 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.632 0.368 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.631 0.369 0.000
H61.2 Impacted cerumen
0.631 0.369 0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified
0.630 0.370 0.000
O41.1 Infection of amniotic sac and membranes
0.630 0.370 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.629 0.371 0.000
H53.0 Amblyopia ex anopsia
0.628 0.372 0.000
W29 Contact with other powered hand tools and household machinery
0.628 0.372 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.628 0.372 0.000
W25 Contact with sharp glass
0.628 0.372 0.000
G00 Bacterial meningitis, not elsewhere classified
0.627 0.373 0.000
T87.4 Infection of amputation stump
0.626 0.374 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.625 0.375 0.000
X78 Intentional self-harm by sharp object
0.625 0.375 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.624 0.376 0.000
H71 Cholesteatoma of middle ear
0.623 0.376 0.000
S65.0 Injury of ulnar artery at wrist and hand level
0.623 0.377 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.623 0.377 0.000
S62.3 Fracture of other metacarpal bone
0.623 0.377 0.000
Z74 Problems related to care-provider dependency
0.622 0.378 0.000
Z39.2 Routine postpartum follow-up
0.622 0.378 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.622 0.378 0.000
S37 Injury of urinary and pelvic organs
0.622 0.378 0.000
S36 Injury of intra-abdominal organs
0.622 0.378 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.622 0.378 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.622 0.378 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.622 0.378 0.000
G80 Infantile cerebral palsy
0.622 0.378 0.000
H02.0 Entropion and trichiasis of eyelid
0.622 0.378 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.621 0.379 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.621 0.379 0.000
H15 Disorders of sclera
0.621 0.379 0.000
H11.1 Conjunctival degenerations and deposits
0.621 0.379 0.000
W17.6 Industrial and construction area
0.621 0.379 0.000
S30.0 Contusion of lower back and pelvis
0.621 0.379 0.000
M89.9 Disorder of bone, unspecified
0.621 0.379 0.000
R26.1 Paralytic gait
0.620 0.380 0.000
Z56 Problems related to employment and unemployment
0.620 0.380 0.000
S11.9 Open wound of neck, part unspecified
0.619 0.381 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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