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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72939083
log Bayes Factor = 14.648
Chromosome 18   position 62,615,975  (GRCh37) Explore rs72939083 on Ensembl!
Variant rs72939083 is part of Cluster X0124

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.999 0.001 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.993 0.007 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.993 0.007 0.000
I25.1 Atherosclerotic heart disease
0.989 0.011 0.000
I20 Angina pectoris
0.985 0.015 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.984 0.016 0.000
I50 Heart failure
0.983 0.017 0.000
I25.2 Old myocardial infarction
0.982 0.018 0.000
I51 Complications and ill-defined descriptions of heart disease
0.978 0.022 0.000
Chapter II Neoplasms
0.967 0.033 0.000
Chapter X Diseases of the respiratory system
0.963 0.037 0.000
I73 Other peripheral vascular diseases
0.956 0.044 0.000
Chapter XXI Factors influencing health status and contact with health services
0.955 0.045 0.000
I51.7 Cardiomegaly
0.954 0.046 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.945 0.055 0.000
I50.1 Left ventricular failure
0.937 0.063 0.000
I21 Acute myocardial infarction
0.934 0.066 0.000
I42 Cardiomyopathy
0.932 0.068 0.000
Chapter XI Diseases of the digestive system
0.925 0.075 0.000
D10-D36 Benign neoplasms
0.924 0.076 0.000
Z85 Personal history of malignant neoplasm
0.923 0.077 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.919 0.081 0.000
J30-J39 Other diseases of upper respiratory tract
0.916 0.084 0.000
I20.9 Angina pectoris, unspecified
0.915 0.085 0.000
I73.9 Peripheral vascular disease, unspecified
0.914 0.086 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.913 0.087 0.000
I60-I69 Cerebrovascular diseases
0.910 0.090 0.000
I50.9 Heart failure, unspecified
0.909 0.091 0.000
I20.8 Other forms of angina pectoris
0.897 0.103 0.000
Chapter XX External causes of morbidity and mortality
0.892 0.108 0.000
I77 Other disorders of arteries and arterioles
0.890 0.110 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.889 0.111 0.000
Z95.1 Presence of aortocoronary bypass graft
0.879 0.121 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.879 0.121 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.878 0.122 0.000
Chapter V Mental and behavioural disorders
0.876 0.124 0.000
I46 Cardiac arrest
0.876 0.124 0.000
K90-K93 Other diseases of the digestive system
0.875 0.125 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.873 0.127 0.000
J34 Other disorders of nose and nasal sinuses
0.872 0.128 0.000
I74 Arterial embolism and thrombosis
0.867 0.133 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.865 0.135 0.000
K40-K46 Hernia
0.861 0.139 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.859 0.141 0.000
J90-J94 Other diseases of pleura
0.859 0.141 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.853 0.147 0.000
K70-K77 Diseases of liver
0.852 0.148 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.850 0.150 0.000
Chapter VII Diseases of the eye and adnexa
0.849 0.151 0.000
I20.0 Unstable angina
0.846 0.154 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.844 0.156 0.000
I31 Other diseases of pericardium
0.842 0.158 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.838 0.162 0.000
I42.0 Dilated cardiomyopathy
0.833 0.167 0.000
K92 Other diseases of digestive system
0.832 0.168 0.000
S50-S59 Injuries to the elbow and forearm
0.828 0.172 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.825 0.175 0.000
I67 Other cerebrovascular diseases
0.824 0.176 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.823 0.177 0.000
S80-S89 Injuries to the knee and lower leg
0.819 0.181 0.000
C77.3 Axillary and upper limb lymph nodes
0.818 0.182 0.000
Z93 Artificial opening status
0.817 0.183 0.000
I80 Phlebitis and thrombophlebitis
0.814 0.186 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.813 0.187 0.000
I51.8 Other ill-defined heart diseases
0.812 0.188 0.000
Chapter VI Diseases of the nervous system
0.811 0.189 0.000
J40-J47 Chronic lower respiratory diseases
0.811 0.189 0.000
Z86 Personal history of certain other diseases
0.810 0.190 0.000
J34.2 Deviated nasal septum
0.809 0.191 0.000
D23 Other benign neoplasms of skin
0.809 0.191 0.000
I49 Other cardiac arrhythmias
0.808 0.192 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.803 0.197 0.000
I21.4 Acute subendocardial myocardial infarction
0.802 0.198 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.802 0.198 0.000
I77.1 Stricture of artery
0.800 0.200 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.794 0.205 0.000
Z90.7 Acquired absence of genital organ(s)
0.792 0.208 0.000
Z86.7 Personal history of diseases of the circulatory system
0.792 0.208 0.000
K76 Other diseases of liver
0.792 0.208 0.000
I25.5 Ischaemic cardiomyopathy
0.788 0.212 0.000
I73.0 Raynaud's syndrome
0.788 0.212 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.786 0.214 0.000
D27 Benign neoplasm of ovary
0.786 0.214 0.000
Z89 Acquired absence of limb
0.785 0.215 0.000
J32 Chronic sinusitis
0.784 0.216 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.783 0.217 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.778 0.222 0.000
I24 Other acute ischaemic heart diseases
0.777 0.223 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.776 0.224 0.000
H30-H36 Disorders of choroid and retina
0.775 0.225 0.000
K40 Inguinal hernia
0.774 0.226 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.773 0.227 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.773 0.227 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.772 0.228 0.000
J43 Emphysema
0.772 0.228 0.000
J34.3 Hypertrophy of nasal turbinates
0.771 0.229 0.000
M05-M14 Inflammatory polyarthropathies
0.770 0.230 0.000
I45 Other conduction disorders
0.769 0.231 0.000
Z80 Family history of malignant neoplasm
0.766 0.234 0.000
D10 Benign neoplasm of mouth and pharynx
0.765 0.235 0.000
F30-F39 Mood [affective] disorders
0.764 0.236 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.763 0.237 0.000
M45-M49 Spondylopathies
0.762 0.238 0.000
I42.9 Cardiomyopathy, unspecified
0.762 0.238 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.759 0.241 0.000
G40-G47 Episodic and paroxysmal disorders
0.756 0.244 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.756 0.244 0.000
S70-S79 Injuries to the hip and thigh
0.754 0.246 0.000
I05-I09 Chronic rheumatic heart diseases
0.754 0.246 0.000
K43 Ventral hernia
0.753 0.247 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.753 0.247 0.000
D23.3 Skin of other and unspecified parts of face
0.753 0.247 0.000
Z85.6 Personal history of leukaemia
0.752 0.248 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.752 0.248 0.000
I70 Atherosclerosis
0.751 0.249 0.000
Chapter VIII Diseases of the ear and mastoid process
0.749 0.251 0.000
I62 Other nontraumatic intracranial haemorrhage
0.748 0.252 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.747 0.252 0.000
Chapter XXII Codes for special purposes
0.746 0.254 0.000
Z60 Problems related to social environment
0.745 0.255 0.000
D17 Benign lipomatous neoplasm
0.745 0.255 0.000
J43.9 Emphysema, unspecified
0.745 0.255 0.000
H35 Other retinal disorders
0.744 0.256 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.743 0.257 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.740 0.260 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.739 0.261 0.000
Z50 Care involving use of rehabilitation procedures
0.737 0.263 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.737 0.263 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.734 0.266 0.000
Z93.3 Colostomy status
0.734 0.266 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.733 0.267 0.000
I46.0 Cardiac arrest with successful resuscitation
0.730 0.270 0.000
J92 Pleural plaque
0.729 0.271 0.000
I38 Endocarditis, valve unspecified
0.729 0.271 0.000
H35.3 Degeneration of macula and posterior pole
0.728 0.272 0.000
X60-X84 Intentional self-harm
0.728 0.272 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.726 0.273 0.000
I46.9 Cardiac arrest, unspecified
0.726 0.274 0.000
I31.3 Pericardial effusion (noninflammatory)
0.725 0.275 0.000
I34 Nonrheumatic mitral valve disorders
0.725 0.275 0.000
K92.0 Haematemesis
0.723 0.277 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.722 0.278 0.000
S40-S49 Injuries to the shoulder and upper arm
0.718 0.281 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.718 0.281 0.000
I74.5 Embolism and thrombosis of iliac artery
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I33 Acute and subacute endocarditis
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
I47 Paroxysmal tachycardia
0.716 0.284 0.000
W20-W49 Exposure to inanimate mechanical forces
0.716 0.284 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.715 0.284 0.000
S52 Fracture of forearm
0.715 0.285 0.000
I71 Aortic aneurysm and dissection
0.715 0.285 0.000
K50-K52 Noninfective enteritis and colitis
0.714 0.286 0.000
S90-S99 Injuries to the ankle and foot
0.714 0.286 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.714 0.286 0.000
I35 Nonrheumatic aortic valve disorders
0.714 0.286 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.713 0.286 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.713 0.287 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.713 0.287 0.000
Z83 Family history of other specific disorders
0.712 0.288 0.000
C77.9 Lymph node, unspecified
0.712 0.288 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.712 0.288 0.000
I72 Other aneurysm
0.712 0.288 0.000
I67.9 Cerebrovascular disease, unspecified
0.711 0.288 0.000
K76.8 Other specified diseases of liver
0.710 0.290 0.000
T79-T79 Certain early complications of trauma
0.710 0.290 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.709 0.291 0.000
M48 Other spondylopathies
0.707 0.293 0.000
I20.1 Angina pectoris with documented spasm
0.706 0.294 0.000
I44 Atrioventricular and left bundle-branch block
0.706 0.294 0.000
T33-T35 Frostbite
0.706 0.294 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.706 0.294 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.706 0.294 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.706 0.294 0.000
T00-T07 Injuries involving multiple body regions
0.706 0.294 0.000
S10-S19 Injuries to the neck
0.706 0.294 0.000
F32 Depressive episode
0.704 0.296 0.000
I78 Diseases of capillaries
0.704 0.296 0.000
T66-T78 Other and unspecified effects of external causes
0.702 0.298 0.000
K92.9 Disease of digestive system, unspecified
0.702 0.298 0.000
Z90.5 Acquired absence of kidney
0.702 0.298 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.701 0.299 0.000
I51.6 Cardiovascular disease, unspecified
0.701 0.299 0.000
I51.5 Myocardial degeneration
0.701 0.299 0.000
I51.4 Myocarditis, unspecified
0.701 0.299 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.701 0.299 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.701 0.299 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.701 0.299 0.000
I51.0 Cardiac septal defect, acquired
0.701 0.299 0.000
J30 Vasomotor and allergic rhinitis
0.701 0.299 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.698 0.301 0.000
D12.5 Sigmoid colon
0.696 0.304 0.000
D12.0 Caecum
0.696 0.304 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.696 0.304 0.000
I50.0 Congestive heart failure
0.696 0.304 0.000
K76.9 Liver disease, unspecified
0.695 0.305 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.695 0.305 0.000
I49.8 Other specified cardiac arrhythmias
0.694 0.306 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.694 0.306 0.000
Z94 Transplanted organ and tissue status
0.694 0.306 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.693 0.306 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.693 0.306 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.693 0.306 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.693 0.307 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.691 0.309 0.000
M06 Other rheumatoid arthritis
0.690 0.310 0.000
G43 Migraine
0.690 0.310 0.000
C77.1 Intrathoracic lymph nodes
0.690 0.310 0.000
H43-H45 Disorders of vitreous body and globe
0.689 0.311 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.689 0.311 0.000
S83.2 Tear of meniscus, current
0.688 0.312 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.688 0.312 0.000
I82 Other venous embolism and thrombosis
0.686 0.314 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.686 0.314 0.000
I73.8 Other specified peripheral vascular diseases
0.686 0.314 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.686 0.314 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.683 0.317 0.000
J90 Pleural effusion, not elsewhere classified
0.682 0.318 0.000
F80-F89 Disorders of psychological development
0.682 0.318 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.682 0.318 0.000
K45 Other abdominal hernia
0.682 0.318 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.682 0.318 0.000
D12.2 Ascending colon
0.682 0.318 0.000
C80 Malignant neoplasm without specification of site
0.681 0.319 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.680 0.320 0.000
Z60.2 Living alone
0.678 0.322 0.000
Z84 Family history of other conditions
0.677 0.323 0.000
Z81 Family history of mental and behavioural disorders
0.677 0.323 0.000
J32.0 Chronic maxillary sinusitis
0.677 0.323 0.000
I51.9 Heart disease, unspecified
0.677 0.323 0.000
Chapter I Certain infectious and parasitic diseases
0.675 0.325 0.000
I69 Sequelae of cerebrovascular disease
0.674 0.326 0.000
Z40 Prophylactic surgery
0.674 0.326 0.000
T93 Sequelae of injuries of lower limb
0.673 0.327 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.671 0.329 0.000
J00-J06 Acute upper respiratory infections
0.671 0.329 0.000
Z92 Personal history of medical treatment
0.671 0.329 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.670 0.330 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.670 0.330 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.670 0.330 0.000
I22 Subsequent myocardial infarction
0.669 0.331 0.000
I42.8 Other cardiomyopathies
0.668 0.332 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.668 0.332 0.000
I42.6 Alcoholic cardiomyopathy
0.668 0.332 0.000
I42.5 Other restrictive cardiomyopathy
0.668 0.332 0.000
I42.4 Endocardial fibroelastosis
0.668 0.332 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.668 0.332 0.000
I42.2 Other hypertrophic cardiomyopathy
0.668 0.332 0.000
M48.0 Spinal stenosis
0.668 0.332 0.000
J93 Pneumothorax
0.667 0.333 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.667 0.333 0.000
D12.3 Transverse colon
0.667 0.333 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.667 0.333 0.000
I67.8 Other specified cerebrovascular diseases
0.667 0.333 0.000
S60-S69 Injuries to the wrist and hand
0.666 0.333 0.000
M50-M54 Other dorsopathies
0.665 0.335 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.662 0.338 0.000
D31 Benign neoplasm of eye and adnexa
0.662 0.338 0.000
D30 Benign neoplasm of urinary organs
0.662 0.338 0.000
D29 Benign neoplasm of male genital organs
0.662 0.338 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.662 0.338 0.000
D26 Other benign neoplasms of uterus
0.662 0.338 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.662 0.338 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.662 0.338 0.000
D19 Benign neoplasm of mesothelial tissue
0.662 0.338 0.000
D16 Benign neoplasm of bone and articular cartilage
0.662 0.338 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.662 0.338 0.000
C78.2 Secondary malignant neoplasm of pleura
0.662 0.338 0.000
F99-F99 Unspecified mental disorder
0.662 0.338 0.000
F32.9 Depressive episode, unspecified
0.662 0.338 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.661 0.338 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.661 0.338 0.000
J60-J70 Lung diseases due to external agents
0.661 0.339 0.000
Z95.0 Presence of cardiac pacemaker
0.661 0.339 0.000
D18 Haemangioma and lymphangioma, any site
0.660 0.340 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.660 0.340 0.000
D34 Benign neoplasm of thyroid gland
0.659 0.341 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.659 0.341 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.659 0.341 0.000
C64-C68 Malignant neoplasms of urinary tract
0.658 0.342 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.658 0.342 0.000
D36 Benign neoplasm of other and unspecified sites
0.658 0.342 0.000
Z90.3 Acquired absence of part of stomach
0.657 0.343 0.000
C73 Malignant neoplasm of thyroid gland
0.657 0.343 0.000
J37 Chronic laryngitis and laryngotracheitis
0.657 0.343 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.656 0.344 0.000
Z90.1 Acquired absence of breast(s)
0.655 0.345 0.000
Z95.3 Presence of xenogenic heart valve
0.654 0.346 0.000
J20-J22 Other acute lower respiratory infections
0.654 0.346 0.000
H40-H42 Glaucoma
0.653 0.347 0.000
Z52 Donors of organs and tissues
0.653 0.347 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.653 0.347 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.652 0.348 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.652 0.348 0.000
I86 Varicose veins of other sites
0.652 0.348 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.652 0.348 0.000
Z97 Presence of other devices
0.651 0.349 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.650 0.350 0.000
J35 Chronic diseases of tonsils and adenoids
0.650 0.350 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.647 0.353 0.000
J31.0 Chronic rhinitis
0.647 0.353 0.000
I87 Other disorders of veins
0.646 0.354 0.000
M91-M94 Chondropathies
0.646 0.354 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.646 0.354 0.000
I63 Cerebral infarction
0.645 0.355 0.000
M80-M85 Disorders of bone density and structure
0.645 0.355 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.644 0.356 0.000
V10-V19 Pedal cyclist injured in transport accident
0.644 0.356 0.000
K75 Other inflammatory liver diseases
0.643 0.357 0.000
G43.9 Migraine, unspecified
0.642 0.358 0.000
V20-V29 Motorcycle rider injured in transport accident
0.642 0.358 0.000
J47 Bronchiectasis
0.642 0.358 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.641 0.359 0.000
I65.2 Occlusion and stenosis of carotid artery
0.641 0.359 0.000
D46 Myelodysplastic syndromes
0.641 0.359 0.000
D37.4 Colon
0.641 0.359 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.640 0.360 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.639 0.361 0.000
Y35-Y36 Legal intervention and operations of war
0.639 0.361 0.000
Y10-Y34 Event of undetermined intent
0.639 0.361 0.000
Y00-Y09 Assault
0.639 0.361 0.000
X85-X99 Assault
0.639 0.361 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.639 0.361 0.000
X50-X57 Overexertion, travel and privation
0.639 0.361 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.639 0.361 0.000
X30-X39 Exposure to forces of nature
0.639 0.361 0.000
X20-X29 Contact with venomous animals and plants
0.639 0.361 0.000
X10-X19 Contact with heat and hot substances
0.639 0.361 0.000
X00-X09 Exposure to smoke, fire and flames
0.639 0.361 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.639 0.361 0.000
W75-W84 Other accidental threats to breathing
0.639 0.361 0.000
W65-W74 Accidental drowning and submersion
0.639 0.361 0.000
W50-W64 Exposure to animate mechanical forces
0.639 0.361 0.000
V98-V99 Other and unspecified transport accidents
0.639 0.361 0.000
V95-V97 Air and space transport accidents
0.639 0.361 0.000
V90-V94 Water transport accidents
0.639 0.361 0.000
V80-V89 Other land transport accidents
0.639 0.361 0.000
V70-V79 Bus occupant injured in transport accident
0.639 0.361 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.639 0.361 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.639 0.361 0.000
V40-V49 Car occupant injured in transport accident
0.639 0.361 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.639 0.361 0.000
V01-V09 Pedestrian injured in transport accident
0.639 0.361 0.000
I77.8 Other specified disorders of arteries and arterioles
0.638 0.362 0.000
I77.6 Arteritis, unspecified
0.638 0.362 0.000
I77.5 Necrosis of artery
0.638 0.362 0.000
I77.4 Coeliac artery compression syndrome
0.638 0.362 0.000
I77.3 Arterial fibromuscular dysplasia
0.638 0.362 0.000
I77.2 Rupture of artery
0.638 0.362 0.000
I77.0 Arteriovenous fistula, acquired
0.638 0.362 0.000
C77.0 Lymph nodes of head, face and neck
0.638 0.362 0.000
I67.1 Cerebral aneurysm, nonruptured
0.635 0.365 0.000
Z50.1 Other physical therapy
0.635 0.365 0.000
D32 Benign neoplasm of meninges
0.634 0.366 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.633 0.366 0.000
K91.4 Colostomy and enterostomy malfunction
0.633 0.367 0.000
K51 Ulcerative colitis
0.633 0.367 0.000
Q60-Q64 Congenital malformations of the urinary system
0.633 0.367 0.000
I47.2 Ventricular tachycardia
0.632 0.368 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.632 0.368 0.000
K55-K64 Other diseases of intestines
0.632 0.368 0.000
M48.06 Spinal stenosis (Lumbar region)
0.632 0.368 0.000
K42 Umbilical hernia
0.632 0.368 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.631 0.369 0.000
J46 Status asthmaticus
0.631 0.369 0.000
D23.5 Skin of trunk
0.630 0.369 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.630 0.370 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.630 0.370 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.630 0.370 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.630 0.370 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.630 0.370 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.630 0.370 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.630 0.370 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.630 0.370 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.630 0.370 0.000
T36 Poisoning by systemic antibiotics
0.630 0.370 0.000
S20-S29 Injuries to the thorax
0.630 0.370 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.630 0.370 0.000
Z80.3 Family history of malignant neoplasm of breast
0.629 0.371 0.000
D10.1 Tongue
0.629 0.371 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.628 0.372 0.000
F70-F79 Mental retardation
0.628 0.372 0.000
F60-F69 Disorders of adult personality and behaviour
0.628 0.372 0.000
I46.1 Sudden cardiac death, so described
0.628 0.372 0.000
Z89.6 Acquired absence of leg above knee
0.628 0.372 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.627 0.373 0.000
J95-J99 Other diseases of the respiratory system
0.627 0.373 0.000
K74 Fibrosis and cirrhosis of liver
0.626 0.374 0.000
T87 Complications peculiar to reattachment and amputation
0.626 0.374 0.000
T86 Failure and rejection of transplanted organs and tissues
0.626 0.374 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.626 0.374 0.000
D37.5 Rectum
0.626 0.374 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.626 0.374 0.000
C78.0 Secondary malignant neoplasm of lung
0.625 0.375 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.625 0.375 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.625 0.375 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.625 0.375 0.000
M05 Seropositive rheumatoid arthritis
0.624 0.376 0.000
Z89.5 Acquired absence of leg at or below knee
0.624 0.376 0.000
Z63 Other problems related to primary support group, including family circumstances
0.624 0.376 0.000
J33 Nasal polyp
0.623 0.377 0.000
H10-H13 Disorders of conjunctiva
0.623 0.377 0.000
Z93.6 Other artificial openings of urinary tract status
0.622 0.378 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.622 0.378 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.621 0.378 0.000
I74.8 Embolism and thrombosis of other arteries
0.621 0.378 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.621 0.378 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.621 0.378 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.621 0.378 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.621 0.378 0.000
T51 Toxic effect of alcohol
0.621 0.379 0.000
Z90.8 Acquired absence of other organs
0.620 0.380 0.000
Z90.0 Acquired absence of part of head and neck
0.620 0.380 0.000
Z50.2 Alcohol rehabilitation
0.620 0.380 0.000
W00-W19 Falls
0.619 0.381 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.618 0.382 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.618 0.382 0.000
Z95.2 Presence of prosthetic heart valve
0.618 0.382 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.618 0.382 0.000
C50-C50 Malignant neoplasm of breast
0.617 0.383 0.000
K46 Unspecified abdominal hernia
0.617 0.383 0.000
T39.1 4-Aminophenol derivatives
0.617 0.383 0.000
C77.8 Lymph nodes of multiple regions
0.616 0.384 0.000
C77.4 Inguinal and lower limb lymph nodes
0.616 0.384 0.000
J94 Other pleural conditions
0.616 0.384 0.000
J91 Pleural effusion in conditions classified elsewhere
0.616 0.384 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.616 0.384 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.615 0.384 0.000
S00-S09 Injuries to the head
0.615 0.385 0.000
D11 Benign neoplasm of major salivary glands
0.615 0.385 0.000
M06.9 Rheumatoid arthritis, unspecified
0.615 0.385 0.000
I85 Oesophageal varices
0.614 0.385 0.000
Z90.2 Acquired absence of lung [part of]
0.614 0.386 0.000
T92 Sequelae of injuries of upper limb
0.613 0.387 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.613 0.387 0.000
D12.8 Rectum
0.612 0.388 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.611 0.388 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.611 0.388 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.611 0.388 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.611 0.388 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.611 0.388 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.611 0.388 0.000
I31.9 Disease of pericardium, unspecified
0.611 0.389 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.611 0.389 0.000
K77 Liver disorders in diseases classified elsewhere
0.611 0.389 0.000
K73 Chronic hepatitis, not elsewhere classified
0.611 0.389 0.000
K72 Hepatic failure, not elsewhere classified
0.611 0.389 0.000
K71 Toxic liver disease
0.611 0.389 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.610 0.390 0.000
D00-D09 In situ neoplasms
0.610 0.390 0.000
I88 Nonspecific lymphadenitis
0.609 0.390 0.000
I81 Portal vein thrombosis
0.609 0.390 0.000
I49.5 Sick sinus syndrome
0.609 0.391 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.609 0.391 0.000
Y40 Systemic antibiotics
0.609 0.391 0.000
H55-H59 Other disorders of eye and adnexa
0.608 0.392 0.000
S52.5 Fracture of lower end of radius
0.607 0.392 0.000
J39 Other diseases of upper respiratory tract
0.607 0.393 0.000
Y43 Primarily systemic agents
0.607 0.393 0.000
K65-K67 Diseases of peritoneum
0.607 0.393 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.606 0.394 0.000
Z83.7 Family history of diseases of the digestive system
0.606 0.394 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.606 0.394 0.000
Z48 Other surgical follow-up care
0.605 0.395 0.000
Y85 Sequelae of transport accidents
0.605 0.395 0.000
M86-M90 Other osteopathies
0.605 0.395 0.000
M60-M63 Disorders of muscles
0.605 0.395 0.000
M00-M03 Infectious arthropathies
0.605 0.395 0.000
K41 Femoral hernia
0.605 0.395 0.000
I45.5 Other specified heart block
0.605 0.395 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.604 0.396 0.000
I31.8 Other specified diseases of pericardium
0.604 0.396 0.000
I31.2 Haemopericardium, not elsewhere classified
0.604 0.396 0.000
I31.1 Chronic constrictive pericarditis
0.604 0.396 0.000
I31.0 Chronic adhesive pericarditis
0.604 0.396 0.000
Z49 Care involving dialysis
0.604 0.396 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.604 0.396 0.000
Z65 Problems related to other psychosocial circumstances
0.601 0.399 0.000
Z64 Problems related to certain psychosocial circumstances
0.601 0.399 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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