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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73184024
log Bayes Factor = 7.44053
Chromosome 3   position 121,830,755  (GRCh37) Explore rs73184024 on Ensembl!
Variant rs73184024 is part of Cluster X0162

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
S00-S09 Injuries to the head
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.991 0.009 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.991 0.009 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.990 0.010 0.000
M70-M79 Other soft tissue disorders
0.986 0.014 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.984 0.016 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.981 0.019 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.980 0.020 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.979 0.021 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.978 0.022 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.975 0.025 0.000
M79.6 Pain in limb
0.975 0.025 0.000
M50-M54 Other dorsopathies
0.972 0.028 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.971 0.029 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.970 0.030 0.000
R41.0 Disorientation, unspecified
0.968 0.032 0.000
E20-E35 Disorders of other endocrine glands
0.965 0.035 0.000
D80-D89 Certain disorders involving the immune mechanism
0.964 0.036 0.000
Chapter X Diseases of the respiratory system
0.963 0.037 0.000
T39.1 4-Aminophenol derivatives
0.953 0.047 0.000
S00 Superficial injury of head
0.940 0.060 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.939 0.061 0.000
D68 Other coagulation defects
0.937 0.063 0.000
E22 Hyperfunction of pituitary gland
0.936 0.064 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.933 0.067 0.000
M50 Cervical disk disorders
0.930 0.070 0.000
E65-E68 Obesity and other hyperalimentation
0.928 0.072 0.000
S02 Fracture of skull and facial bones
0.927 0.073 0.000
M40-M43 Deforming dorsopathies
0.926 0.074 0.000
D86 Sarcoidosis
0.921 0.079 0.000
M54 Dorsalgia
0.917 0.083 0.000
S06 Intracranial injury
0.917 0.083 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.913 0.087 0.000
S09 Other and unspecified injuries of head
0.911 0.089 0.000
Chapter VI Diseases of the nervous system
0.898 0.102 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.896 0.104 0.000
E66 Obesity
0.892 0.108 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.890 0.110 0.000
M79.67 Pain in limb (Ankle and foot)
0.890 0.110 0.000
Chapter VIII Diseases of the ear and mastoid process
0.888 0.112 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.884 0.116 0.000
E66.8 Other obesity
0.877 0.123 0.000
E10-E14 Diabetes mellitus
0.871 0.129 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.868 0.132 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.865 0.135 0.000
R47-R49 Symptoms and signs involving speech and voice
0.864 0.136 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.861 0.139 0.000
J90-J94 Other diseases of pleura
0.861 0.139 0.000
M71 Other bursopathies
0.859 0.141 0.000
M41 Scoliosis
0.856 0.144 0.000
M79.66 Pain in limb (Lower leg)
0.855 0.145 0.000
S50-S59 Injuries to the elbow and forearm
0.852 0.148 0.000
S10-S19 Injuries to the neck
0.851 0.149 0.000
J90 Pleural effusion, not elsewhere classified
0.848 0.152 0.000
D68.9 Coagulation defect, unspecified
0.847 0.153 0.000
S00.8 Superficial injury of other parts of head
0.847 0.153 0.000
M60-M63 Disorders of muscles
0.846 0.154 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.844 0.156 0.000
S05 Injury of eye and orbit
0.844 0.156 0.000
H80-H83 Diseases of inner ear
0.841 0.159 0.000
S90-S99 Injuries to the ankle and foot
0.835 0.165 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.833 0.167 0.000
D86.9 Sarcoidosis, unspecified
0.833 0.167 0.000
D86.0 Sarcoidosis of lung
0.832 0.168 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.830 0.170 0.000
D69 Purpura and other haemorrhagic conditions
0.822 0.178 0.000
T39.0 Salicylates
0.822 0.178 0.000
M54.1 Radiculopathy
0.820 0.180 0.000
S80-S89 Injuries to the knee and lower leg
0.820 0.180 0.000
M50.3 Other cervical disk degeneration
0.818 0.182 0.000
S09.9 Unspecified injury of head
0.818 0.182 0.000
Chapter XXII Codes for special purposes
0.818 0.182 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.817 0.182 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.817 0.183 0.000
M79.1 Myalgia
0.813 0.187 0.000
G90-G99 Other disorders of the nervous system
0.811 0.189 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.809 0.191 0.000
D68.8 Other specified coagulation defects
0.809 0.191 0.000
M41.9 Scoliosis, unspecified
0.806 0.194 0.000
H81 Disorders of vestibular function
0.805 0.195 0.000
E22.0 Acromegaly and pituitary gigantism
0.802 0.198 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.802 0.198 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.801 0.199 0.000
Y44 Agents primarily affecting blood constituents
0.801 0.199 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.800 0.200 0.000
M50.1 Cervical disk disorder with radiculopathy
0.798 0.202 0.000
E11 Non-insulin-dependent diabetes mellitus
0.798 0.202 0.000
Y00-Y09 Assault
0.796 0.203 0.000
R40 Somnolence, stupor and coma
0.796 0.204 0.000
T79-T79 Certain early complications of trauma
0.796 0.204 0.000
J00-J06 Acute upper respiratory infections
0.794 0.206 0.000
M79.0 Rheumatism, unspecified
0.794 0.206 0.000
R94 Abnormal results of function studies
0.791 0.209 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.790 0.210 0.000
M50.2 Other cervical disk displacement
0.788 0.212 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.785 0.215 0.000
T66-T78 Other and unspecified effects of external causes
0.785 0.215 0.000
R46 Symptoms and signs involving appearance and behaviour
0.783 0.217 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.783 0.217 0.000
Y45.1 Salicylates
0.782 0.218 0.000
M54.5 Low back pain
0.782 0.218 0.000
T14 Injury of unspecified body region
0.781 0.219 0.000
M79.64 Pain in limb (Hand)
0.779 0.221 0.000
E24 Cushing's syndrome
0.777 0.223 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.777 0.223 0.000
Y40 Systemic antibiotics
0.775 0.225 0.000
J60-J70 Lung diseases due to external agents
0.774 0.226 0.000
Y57 Other and unspecified drugs and medicaments
0.773 0.227 0.000
S06.0 Concussion
0.773 0.227 0.000
S83.2 Tear of meniscus, current
0.773 0.227 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.770 0.230 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.770 0.230 0.000
S52 Fracture of forearm
0.769 0.231 0.000
W50-W64 Exposure to animate mechanical forces
0.767 0.233 0.000
V40-V49 Car occupant injured in transport accident
0.766 0.234 0.000
W20-W49 Exposure to inanimate mechanical forces
0.766 0.234 0.000
R41.2 Retrograde amnesia
0.766 0.234 0.000
S02.2 Fracture of nasal bones
0.763 0.237 0.000
S60-S69 Injuries to the wrist and hand
0.760 0.240 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.759 0.241 0.000
E27 Other disorders of adrenal gland
0.759 0.241 0.000
Y45.2 Propionic acid derivatives
0.758 0.242 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.757 0.242 0.000
M54.2 Cervicalgia
0.757 0.243 0.000
D68.2 Hereditary deficiency of other clotting factors
0.756 0.244 0.000
Q50-Q56 Congenital malformations of genital organs
0.755 0.245 0.000
M54.12 Radiculopathy (Cervical region)
0.754 0.246 0.000
M71.2 Synovial cyst of popliteal space [Baker]
0.754 0.246 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.754 0.246 0.000
E23 Hypofunction and other disorders of pituitary gland
0.753 0.247 0.000
G62 Other polyneuropathies
0.751 0.249 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.750 0.250 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.749 0.251 0.000
J40-J47 Chronic lower respiratory diseases
0.749 0.251 0.000
G60 Hereditary and idiopathic neuropathy
0.748 0.252 0.000
R21 Rash and other nonspecific skin eruption
0.748 0.252 0.000
H81.0 Meniere's disease
0.748 0.252 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.747 0.253 0.000
E11.4 With neurological complications
0.746 0.254 0.000
D55-D59 Haemolytic anaemias
0.746 0.254 0.000
D66 Hereditary factor VIII deficiency
0.745 0.255 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.745 0.255 0.000
M79.63 Pain in limb (Forearm)
0.745 0.255 0.000
S20-S29 Injuries to the thorax
0.744 0.256 0.000
S00.7 Multiple superficial injuries of head
0.744 0.256 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.743 0.257 0.000
S02.8 Fractures of other skull and facial bones
0.743 0.257 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.742 0.258 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.742 0.258 0.000
X20-X29 Contact with venomous animals and plants
0.741 0.258 0.000
S00.0 Superficial injury of scalp
0.741 0.258 0.000
R94.5 Abnormal results of liver function studies
0.741 0.259 0.000
S02.1 Fracture of base of skull
0.741 0.259 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.741 0.259 0.000
S00.3 Superficial injury of nose
0.741 0.259 0.000
R80 Isolated proteinuria
0.740 0.260 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.740 0.260 0.000
S09.8 Other specified injuries of head
0.740 0.260 0.000
E29 Testicular dysfunction
0.739 0.260 0.000
H60-H62 Diseases of external ear
0.738 0.261 0.000
V10-V19 Pedal cyclist injured in transport accident
0.738 0.262 0.000
D80 Immunodeficiency with predominantly antibody defects
0.737 0.263 0.000
M62 Other disorders of muscle
0.737 0.263 0.000
T36 Poisoning by systemic antibiotics
0.737 0.263 0.000
D69.5 Secondary thrombocytopenia
0.736 0.264 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.736 0.264 0.000
M43 Other deforming dorsopathies
0.736 0.264 0.000
M86-M90 Other osteopathies
0.735 0.265 0.000
E50-E64 Other nutritional deficiencies
0.734 0.266 0.000
G63.2 Diabetic polyneuropathy
0.734 0.266 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.733 0.267 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.733 0.267 0.000
V20-V29 Motorcycle rider injured in transport accident
0.731 0.269 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.731 0.269 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.731 0.269 0.000
G93 Other disorders of brain
0.730 0.270 0.000
S02.3 Fracture of orbital floor
0.730 0.270 0.000
E13 Other specified diabetes mellitus
0.730 0.270 0.000
X50-X57 Overexertion, travel and privation
0.730 0.270 0.000
T92 Sequelae of injuries of upper limb
0.729 0.271 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.729 0.271 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.728 0.272 0.000
S00.1 Contusion of eyelid and periocular area
0.727 0.273 0.000
M76 Enthesopathies of lower limb, excluding foot
0.727 0.273 0.000
D68.6 Other Thrombophilia
0.725 0.275 0.000
R49 Voice disturbances
0.723 0.277 0.000
M00-M03 Infectious arthropathies
0.722 0.278 0.000
M54.9 Dorsalgia, unspecified
0.720 0.280 0.000
E26 Hyperaldosteronism
0.720 0.280 0.000
J86 Pyothorax
0.719 0.281 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.718 0.282 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.716 0.284 0.000
S08 Traumatic amputation of part of head
0.715 0.285 0.000
S07 Crushing injury of head
0.715 0.285 0.000
S04 Injury of cranial nerves
0.715 0.285 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.715 0.285 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.713 0.286 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.712 0.288 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.711 0.289 0.000
R40.2 Coma, unspecified
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.290 0.000
Y10-Y34 Event of undetermined intent
0.710 0.290 0.000
X85-X99 Assault
0.710 0.290 0.000
X30-X39 Exposure to forces of nature
0.710 0.290 0.000
X10-X19 Contact with heat and hot substances
0.710 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.290 0.000
W75-W84 Other accidental threats to breathing
0.710 0.290 0.000
W65-W74 Accidental drowning and submersion
0.710 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
V95-V97 Air and space transport accidents
0.710 0.290 0.000
V90-V94 Water transport accidents
0.710 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.290 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.710 0.290 0.000
M79.19 Myalgia (Site unspecified)
0.709 0.291 0.000
S06.4 Epidural haemorrhage
0.708 0.292 0.000
Y48 Anaesthetics and therapeutic gases
0.708 0.292 0.000
R47 Speech disturbances, not elsewhere classified
0.708 0.292 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.707 0.293 0.000
T13 Other injuries of lower limb, level unspecified
0.707 0.293 0.000
M79.5 Residual foreign body in soft tissue
0.706 0.294 0.000
H80 Otosclerosis
0.705 0.295 0.000
S52.6 Fracture of lower end of both ulna and radius
0.704 0.296 0.000
Chapter I Certain infectious and parasitic diseases
0.704 0.296 0.000
R43 Disturbances of smell and taste
0.703 0.297 0.000
S06.9 Intracranial injury, unspecified
0.703 0.297 0.000
M79.9 Soft tissue disorder, unspecified
0.702 0.297 0.000
M79.3 Panniculitis, unspecified
0.702 0.297 0.000
Y59 Other and unspecified vaccines and biological substances
0.702 0.298 0.000
Y58 Bacterial vaccines
0.702 0.298 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.702 0.298 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.702 0.298 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.702 0.298 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.702 0.298 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.702 0.298 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.702 0.298 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.702 0.298 0.000
J06.9 Acute upper respiratory infection, unspecified
0.702 0.298 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.702 0.298 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.701 0.299 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.701 0.299 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.701 0.299 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.701 0.299 0.000
S10 Superficial injury of neck
0.700 0.300 0.000
S92 Fracture of foot, except ankle
0.700 0.300 0.000
M79.60 Pain in limb (Multiple sites)
0.700 0.300 0.000
R41.1 Anterograde amnesia
0.699 0.301 0.000
M79.68 Pain in limb (Other)
0.699 0.301 0.000
M79.61 Pain in limb (Shoulder region)
0.699 0.301 0.000
M45-M49 Spondylopathies
0.698 0.302 0.000
S91 Open wound of ankle and foot
0.698 0.302 0.000
Y43 Primarily systemic agents
0.697 0.302 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.697 0.303 0.000
J45 Asthma
0.697 0.303 0.000
E34 Other endocrine disorders
0.697 0.303 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.696 0.303 0.000
R76 Other abnormal immunological findings in serum
0.697 0.303 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.696 0.304 0.000
T39.4 Antirheumatics, not elsewhere classified
0.696 0.304 0.000
T39.2 Pyrazolone derivatives
0.696 0.304 0.000
D67 Hereditary factor IX deficiency
0.696 0.304 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.696 0.304 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.695 0.304 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.695 0.305 0.000
M79.2 Neuralgia and neuritis, unspecified
0.693 0.307 0.000
E66.0 Obesity due to excess calories
0.693 0.307 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.693 0.307 0.000
X60-X84 Intentional self-harm
0.692 0.308 0.000
M53 Other dorsopathies, not elsewhere classified
0.692 0.308 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.692 0.308 0.000
E32 Diseases of thymus
0.692 0.308 0.000
E31 Polyglandular dysfunction
0.692 0.308 0.000
E30 Disorders of puberty, not elsewhere classified
0.692 0.308 0.000
E25 Adrenogenital disorders
0.692 0.308 0.000
E20 Hypoparathyroidism
0.692 0.308 0.000
D84 Other immunodeficiencies
0.691 0.309 0.000
D83 Common variable immunodeficiency
0.691 0.309 0.000
D82 Immunodeficiency associated with other major defects
0.691 0.309 0.000
D81 Combined immunodeficiencies
0.691 0.309 0.000
J30-J39 Other diseases of upper respiratory tract
0.690 0.310 0.000
R23 Other skin changes
0.690 0.310 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.688 0.312 0.000
H81.2 Vestibular neuronitis
0.688 0.312 0.000
T91 Sequelae of injuries of neck and trunk
0.688 0.312 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.687 0.313 0.000
Q00-Q07 Congenital malformations of the nervous system
0.686 0.314 0.000
Y84.8 Other medical procedures
0.685 0.315 0.000
R25 Abnormal involuntary movements
0.684 0.316 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.684 0.316 0.000
E28 Ovarian dysfunction
0.683 0.317 0.000
S02.5 Fracture of tooth
0.682 0.318 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.682 0.318 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.682 0.318 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.682 0.318 0.000
M54.4 Lumbago with sciatica
0.682 0.318 0.000
J40 Bronchitis, not specified as acute or chronic
0.681 0.319 0.000
E11.3 With ophthalmic complications
0.681 0.319 0.000
J85 Abscess of lung and mediastinum
0.680 0.320 0.000
W00-W19 Falls
0.680 0.320 0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg
0.679 0.321 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.678 0.322 0.000
S52.1 Fracture of upper end of radius
0.678 0.322 0.000
R15 Faecal incontinence
0.677 0.323 0.000
J20-J22 Other acute lower respiratory infections
0.676 0.324 0.000
S00.5 Superficial injury of lip and oral cavity
0.674 0.326 0.000
S00.4 Superficial injury of ear
0.674 0.326 0.000
D68.4 Acquired coagulation factor deficiency
0.672 0.328 0.000
D68.1 Hereditary factor XI deficiency
0.672 0.328 0.000
G90 Disorders of autonomic nervous system
0.672 0.328 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.671 0.329 0.000
E22.8 Other hyperfunction of pituitary gland
0.671 0.329 0.000
E22.1 Hyperprolactinaemia
0.671 0.329 0.000
S02.4 Fracture of malar and maxillary bones
0.671 0.329 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.671 0.329 0.000
J34 Other disorders of nose and nasal sinuses
0.670 0.330 0.000
S06.00 Concussion (without open intracranial wound)
0.670 0.330 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.670 0.330 0.000
R94.4 Abnormal results of kidney function studies
0.669 0.331 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.669 0.331 0.000
Y45.8 Other analgesics and antipyretics
0.669 0.331 0.000
Y45.5 4-Aminophenol derivatives
0.669 0.331 0.000
Y45.4 Antirheumatics
0.669 0.331 0.000
M50.0 Cervical disk disorder with myelopathy
0.669 0.331 0.000
S19 Other and unspecified injuries of neck
0.668 0.332 0.000
T14.1 Open wound of unspecified body region
0.668 0.332 0.000
Y40.0 Penicillins
0.668 0.332 0.000
S02.0 Fracture of vault of skull
0.667 0.332 0.000
M79.69 Pain in limb (Site unspecified)
0.667 0.332 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.667 0.333 0.000
M50.9 Cervical disk disorder, unspecified
0.667 0.333 0.000
M50.8 Other cervical disk disorders
0.667 0.333 0.000
Q60-Q64 Congenital malformations of the urinary system
0.666 0.334 0.000
E67 Other hyperalimentation
0.665 0.335 0.000
E68 Sequelae of hyperalimentation
0.665 0.335 0.000
M54.55 Low back pain (Thoracolumbar region)
0.665 0.335 0.000
S02.7 Multiple fractures involving skull and facial bones
0.664 0.335 0.000
M42 Spinal osteochondrosis
0.664 0.336 0.000
M40 Kyphosis and lordosis
0.664 0.336 0.000
S06.2 Diffuse brain injury
0.663 0.336 0.000
T78 Adverse effects, not elsewhere classified
0.663 0.337 0.000
S06.3 Focal brain injury
0.663 0.337 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.663 0.337 0.000
D68.0 Von Willebrand's disease
0.662 0.337 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.662 0.338 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.661 0.339 0.000
D86.3 Sarcoidosis of skin
0.661 0.339 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.661 0.339 0.000
D86.1 Sarcoidosis of lymph nodes
0.661 0.339 0.000
S06.5 Traumatic subdural haemorrhage
0.660 0.340 0.000
E11.5 With peripheral circulatory complications
0.660 0.340 0.000
D86.8 Sarcoidosis of other and combined sites
0.659 0.340 0.000
Q80-Q89 Other congenital malformations
0.659 0.340 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.659 0.341 0.000
M54.8 Other dorsalgia
0.657 0.343 0.000
M54.0 Panniculitis affecting regions of neck and back
0.657 0.343 0.000
Y04 Assault by bodily force
0.657 0.343 0.000
S06.8 Other intracranial injuries
0.657 0.343 0.000
S06.7 Intracranial injury with prolonged coma
0.657 0.343 0.000
S06.1 Traumatic cerebral oedema
0.657 0.343 0.000
W22 Striking against or struck by other objects
0.657 0.343 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.657 0.343 0.000
M91-M94 Chondropathies
0.657 0.343 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.655 0.345 0.000
Q35-Q37 Cleft lip and cleft palate
0.655 0.345 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.655 0.345 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.655 0.345 0.000
S02.6 Fracture of mandible
0.655 0.345 0.000
J69 Pneumonitis due to solids and liquids
0.655 0.345 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.655 0.345 0.000
S09.7 Multiple injuries of head
0.653 0.347 0.000
S09.2 Traumatic rupture of ear drum
0.653 0.347 0.000
S09.1 Injury of muscle and tendon of head
0.653 0.347 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.653 0.347 0.000
J04 Acute laryngitis and tracheitis
0.652 0.348 0.000
J45.0 Predominantly allergic asthma
0.652 0.348 0.000
G62.8 Other specified polyneuropathies
0.651 0.349 0.000
S52.60 Fracture of lower end of both ulna and radius (closed)
0.650 0.350 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.649 0.351 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.649 0.351 0.000
M72 Fibroblastic disorders
0.649 0.351 0.000
Y42.5 Other oestrogens and progestogens
0.649 0.351 0.000
M71.3 Other bursal cyst
0.648 0.352 0.000
S02.20 Fracture of nasal bones (closed)
0.646 0.354 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.646 0.354 0.000
Y44.5 Thrombolytic drugs
0.646 0.354 0.000
G91 Hydrocephalus
0.645 0.355 0.000
S64 Injury of nerves at wrist and hand level
0.644 0.356 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.643 0.356 0.000
Y52 Agents primarily affecting the cardiovascular system
0.643 0.357 0.000
E24.9 Cushing's syndrome, unspecified
0.643 0.357 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.642 0.358 0.000
R44.1 Visual hallucinations
0.641 0.359 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.641 0.359 0.000
R46.8 Other symptoms and signs involving appearance and behaviour
0.641 0.359 0.000
R27 Other lack of coordination
0.640 0.360 0.000
V80-V89 Other land transport accidents
0.640 0.360 0.000
R18 Ascites
0.640 0.360 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.639 0.361 0.000
E66.1 Drug-induced obesity
0.639 0.361 0.000
E40-E46 Malnutrition
0.638 0.361 0.000
T11 Other injuries of upper limb, level unspecified
0.638 0.362 0.000
T09 Other injuries of spine and trunk, level unspecified
0.638 0.362 0.000
T12.X1 Fracture of lower limb, level unspecified (open)
0.638 0.362 0.000
T12.X0 Fracture of lower limb, level unspecified (closed)
0.638 0.362 0.000
T12 Fracture of lower limb, level unspecified
0.638 0.362 0.000
T10.X1 Fracture of upper limb, level unspecified (open)
0.638 0.362 0.000
T10.X0 Fracture of upper limb, level unspecified (closed)
0.638 0.362 0.000
T10 Fracture of upper limb, level unspecified
0.638 0.362 0.000
T08.X1 Fracture of spine, level unspecified (open)
0.638 0.362 0.000
T08.X0 Fracture of spine, level unspecified (closed)
0.638 0.362 0.000
T08 Fracture of spine, level unspecified
0.638 0.362 0.000
M54.29 Cervicalgia-Site unspe
0.638 0.362 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.637 0.362 0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen
0.636 0.364 0.000
M54.19 Radiculopathy (Site unspecified)
0.634 0.366 0.000
A30-A49 Other bacterial diseases
0.634 0.366 0.000
E65 Localised adiposity
0.633 0.367 0.000
R76.8 Other specified abnormal immunological findings in serum
0.633 0.367 0.000
M79.62 Pain in limb (Upper arm)
0.633 0.367 0.000
S27 Injury of other and unspecified intrathoracic organs
0.633 0.367 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.633 0.367 0.000
J34.2 Deviated nasal septum
0.632 0.368 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.631 0.369 0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.631 0.369 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.630 0.369 0.000
G60.0 Hereditary motor and sensory neuropathy
0.630 0.370 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.630 0.370 0.000
J86.9 Pyothorax without fistula
0.630 0.370 0.000
S62 Fracture at wrist and hand level
0.629 0.371 0.000
E13.9 Without complications
0.629 0.371 0.000
J84 Other interstitial pulmonary diseases
0.629 0.371 0.000
T14.0 Superficial injury of unspecified body region
0.628 0.372 0.000
M62.8 Other specified disorders of muscle
0.627 0.373 0.000
E12 Malnutrition-related diabetes mellitus
0.625 0.375 0.000
R74 Abnormal serum enzyme levels
0.625 0.375 0.000
M77 Other enthesopathies
0.624 0.376 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.623 0.377 0.000
G64 Other disorders of peripheral nervous system
0.623 0.377 0.000
Y57.6 Other diagnostic agents
0.622 0.378 0.000
M05-M14 Inflammatory polyarthropathies
0.622 0.378 0.000
H60 Otitis externa
0.622 0.378 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.621 0.379 0.000
J94 Other pleural conditions
0.620 0.380 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.619 0.380 0.000
E23.2 Diabetes insipidus
0.618 0.382 0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.618 0.382 0.000
S67 Crushing injury of wrist and hand
0.617 0.382 0.000
R73 Elevated blood glucose level
0.617 0.383 0.000
B15-B19 Viral hepatitis
0.617 0.383 0.000
G70-G73 Diseases of myoneural junction and muscle
0.616 0.384 0.000
E11.6 With other specified complications
0.616 0.384 0.000
M71.9 Bursopathy, unspecified
0.616 0.384 0.000
M71.8 Other specified bursopathies
0.616 0.384 0.000
M71.5 Other bursitis, not elsewhere classified
0.616 0.384 0.000
M71.4 Calcium deposit in bursa
0.616 0.384 0.000
M71.1 Other infective bursitis
0.616 0.384 0.000
M71.0 Abscess of bursa
0.616 0.384 0.000
R49.0 Dysphonia
0.616 0.384 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.615 0.385 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.614 0.386 0.000
Y84.2 Radiological procedure and radiotherapy
0.614 0.386 0.000
M41.8 Other forms of scoliosis
0.614 0.386 0.000
M41.5 Other secondary scoliosis
0.614 0.386 0.000
M41.4 Neuromuscular scoliosis
0.614 0.386 0.000
M41.3 Thoracogenic scoliosis
0.614 0.386 0.000
M41.2 Other idiopathic scoliosis
0.614 0.386 0.000
M41.1 Juvenile idiopathic scoliosis
0.614 0.386 0.000
M41.0 Infantile idiopathic scoliosis
0.614 0.386 0.000
S05.1 Contusion of eyeball and orbital tissues
0.614 0.386 0.000
H90-H95 Other disorders of ear
0.614 0.386 0.000
Y44.2 Anticoagulants
0.613 0.387 0.000
J09-J18 Influenza and pneumonia
0.613 0.387 0.000
S52.10 Fracture of upper end of radius (closed)
0.612 0.388 0.000
S02.80 Fractures of other skull and facial bones (closed)
0.611 0.389 0.000
E27.8 Other specified disorders of adrenal gland
0.611 0.389 0.000
S59 Other and unspecified injuries of forearm
0.610 0.389 0.000
S58 Traumatic amputation of forearm
0.610 0.389 0.000
S57 Crushing injury of forearm
0.610 0.389 0.000
S56 Injury of muscle and tendon at forearm level
0.610 0.389 0.000
S55 Injury of blood vessels at forearm level
0.610 0.389 0.000
S54 Injury of nerves at forearm level
0.610 0.389 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.610 0.389 0.000
S17 Crushing injury of neck
0.610 0.390 0.000
S15 Injury of blood vessels at neck level
0.610 0.390 0.000
S14 Injury of nerves and spinal cord at neck level
0.610 0.390 0.000
S11 Open wound of neck
0.610 0.390 0.000
S18 Traumatic amputation at neck level
0.610 0.390 0.000
S16 Injury of muscle and tendon at neck level
0.610 0.390 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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