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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73338448
log Bayes Factor = 13.7418
Chromosome 10   position 99,882,156  (GRCh37) Explore rs73338448 on Ensembl!
Variant rs73338448 is part of Cluster X0134

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.998 0.002 0.000
I20-I25 Ischaemic heart diseases
0.998 0.002 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.995 0.005 0.000
J40-J47 Chronic lower respiratory diseases
0.993 0.007 0.000
J90-J94 Other diseases of pleura
0.991 0.009 0.000
I10-I15 Hypertensive diseases
0.990 0.010 0.000
K55-K64 Other diseases of intestines
0.989 0.011 0.000
J44 Other chronic obstructive pulmonary disease
0.989 0.011 0.000
I25 Chronic ischaemic heart disease
0.989 0.011 0.000
C64-C68 Malignant neoplasms of urinary tract
0.987 0.013 0.000
I21 Acute myocardial infarction
0.985 0.015 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.984 0.016 0.000
Chapter XX External causes of morbidity and mortality
0.983 0.017 0.000
Chapter VI Diseases of the nervous system
0.981 0.019 0.000
I10 Essential (primary) hypertension
0.979 0.021 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.977 0.023 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.976 0.024 0.000
J95-J99 Other diseases of the respiratory system
0.968 0.032 0.000
Chapter I Certain infectious and parasitic diseases
0.965 0.035 0.000
K86 Other diseases of pancreas
0.965 0.035 0.000
C51-C58 Malignant neoplasms of female genital organs
0.961 0.039 0.000
K56.6 Other and unspecified intestinal obstruction
0.958 0.042 0.000
C67 Malignant neoplasm of bladder
0.953 0.047 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.953 0.047 0.000
J92 Pleural plaque
0.951 0.049 0.000
I25.1 Atherosclerotic heart disease
0.950 0.050 0.000
C15-C26 Malignant neoplasms of digestive organs
0.944 0.056 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.943 0.057 0.000
Chapter VIII Diseases of the ear and mastoid process
0.942 0.058 0.000
J98 Other respiratory disorders
0.936 0.064 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.936 0.064 0.000
A30-A49 Other bacterial diseases
0.935 0.065 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.935 0.065 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.933 0.067 0.000
J30-J39 Other diseases of upper respiratory tract
0.931 0.069 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.931 0.069 0.000
J92.0 Pleural plaque with presence of asbestos
0.930 0.070 0.000
J93 Pneumothorax
0.924 0.076 0.000
K70-K77 Diseases of liver
0.917 0.083 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.912 0.088 0.000
K57 Diverticular disease of intestine
0.912 0.088 0.000
K63 Other diseases of intestine
0.911 0.089 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.907 0.093 0.000
J34 Other disorders of nose and nasal sinuses
0.906 0.094 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.906 0.094 0.000
E70-E90 Metabolic disorders
0.903 0.097 0.000
I21.4 Acute subendocardial myocardial infarction
0.901 0.099 0.000
S90-S99 Injuries to the ankle and foot
0.899 0.101 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.899 0.101 0.000
S40-S49 Injuries to the shoulder and upper arm
0.896 0.104 0.000
C56 Malignant neoplasm of ovary
0.893 0.107 0.000
K63.8 Other specified diseases of intestine
0.889 0.111 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.886 0.114 0.000
A41 Other septicaemia
0.886 0.114 0.000
I25.2 Old myocardial infarction
0.885 0.115 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.885 0.115 0.000
G81 Hemiplegia
0.884 0.116 0.000
K60 Fissure and fistula of anal and rectal regions
0.882 0.118 0.000
J98.1 Pulmonary collapse
0.879 0.121 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.878 0.122 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.878 0.122 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.878 0.122 0.000
L20-L30 Dermatitis and eczema
0.877 0.123 0.000
K56.2 Volvulus
0.872 0.128 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.870 0.130 0.000
A00-A09 Intestinal infectious diseases
0.868 0.132 0.000
K76 Other diseases of liver
0.866 0.134 0.000
K85 Acute pancreatitis
0.865 0.135 0.000
K81 Cholecystitis
0.863 0.137 0.000
K83 Other diseases of biliary tract
0.861 0.139 0.000
E20-E35 Disorders of other endocrine glands
0.858 0.142 0.000
K82 Other diseases of gallbladder
0.849 0.151 0.000
J93.9 Pneumothorax, unspecified
0.848 0.152 0.000
Chapter V Mental and behavioural disorders
0.848 0.152 0.000
G81.9 Hemiplegia, unspecified
0.847 0.153 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.847 0.153 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.844 0.156 0.000
S20-S29 Injuries to the thorax
0.843 0.157 0.000
K50-K52 Noninfective enteritis and colitis
0.843 0.157 0.000
S00-S09 Injuries to the head
0.841 0.159 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.841 0.159 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.840 0.160 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.836 0.164 0.000
Y86 Sequelae of other accidents
0.835 0.165 0.000
I12 Hypertensive renal disease
0.834 0.166 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.834 0.166 0.000
G61 Inflammatory polyneuropathy
0.832 0.168 0.000
C67.6 Ureteric orifice
0.828 0.172 0.000
H65-H75 Diseases of middle ear and mastoid
0.826 0.174 0.000
S42 Fracture of shoulder and upper arm
0.825 0.174 0.000
C53 Malignant neoplasm of cervix uteri
0.824 0.176 0.000
J46 Status asthmaticus
0.824 0.176 0.000
K86.1 Other chronic pancreatitis
0.822 0.178 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.822 0.178 0.000
C67.9 Bladder, unspecified
0.819 0.181 0.000
A49 Bacterial infection of unspecified site
0.818 0.182 0.000
J43 Emphysema
0.818 0.182 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.816 0.184 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.816 0.184 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.816 0.184 0.000
Y43 Primarily systemic agents
0.815 0.185 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.812 0.188 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.812 0.188 0.000
K86.2 Cyst of pancreas
0.811 0.189 0.000
G30-G32 Other degenerative diseases of the nervous system
0.811 0.189 0.000
L30 Other dermatitis
0.811 0.189 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.806 0.194 0.000
K60.3 Anal fistula
0.806 0.194 0.000
A41.9 Septicaemia, unspecified
0.805 0.195 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.804 0.196 0.000
J34.2 Deviated nasal septum
0.804 0.196 0.000
C67.4 Posterior wall of bladder
0.802 0.198 0.000
J60-J70 Lung diseases due to external agents
0.801 0.199 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.800 0.200 0.000
Y45.0 Opioids and related analgesics
0.799 0.201 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.798 0.202 0.000
Chapter XXII Codes for special purposes
0.795 0.204 0.000
J98.4 Other disorders of lung
0.792 0.207 0.000
C71 Malignant neoplasm of brain
0.791 0.209 0.000
S70-S79 Injuries to the hip and thigh
0.790 0.210 0.000
W20-W49 Exposure to inanimate mechanical forces
0.788 0.212 0.000
A04 Other bacterial intestinal infections
0.788 0.212 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.787 0.213 0.000
J39 Other diseases of upper respiratory tract
0.785 0.215 0.000
G61.0 Guillain-Barre syndrome
0.784 0.216 0.000
K83.1 Obstruction of bile duct
0.784 0.216 0.000
H90-H95 Other disorders of ear
0.784 0.216 0.000
C25 Malignant neoplasm of pancreas
0.783 0.217 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.782 0.218 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.779 0.221 0.000
J42 Unspecified chronic bronchitis
0.779 0.221 0.000
S90 Superficial injury of ankle and foot
0.779 0.221 0.000
C15 Malignant neoplasm of oesophagus
0.778 0.222 0.000
G82 Paraplegia and tetraplegia
0.776 0.224 0.000
E87.6 Hypokalaemia
0.775 0.225 0.000
J90 Pleural effusion, not elsewhere classified
0.775 0.225 0.000
H80-H83 Diseases of inner ear
0.774 0.226 0.000
D69 Purpura and other haemorrhagic conditions
0.774 0.226 0.000
J91 Pleural effusion in conditions classified elsewhere
0.773 0.227 0.000
C67.2 Lateral wall of bladder
0.770 0.230 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.770 0.230 0.000
C80 Malignant neoplasm without specification of site
0.767 0.233 0.000
C18 Malignant neoplasm of colon
0.765 0.235 0.000
K86.3 Pseudocyst of pancreas
0.765 0.235 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.765 0.235 0.000
S01 Open wound of head
0.764 0.235 0.000
K81.0 Acute cholecystitis
0.764 0.236 0.000
L30.9 Dermatitis, unspecified
0.764 0.236 0.000
E65-E68 Obesity and other hyperalimentation
0.764 0.236 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.762 0.238 0.000
L40-L45 Papulosquamous disorders
0.761 0.239 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.760 0.240 0.000
J93.1 Other spontaneous pneumothorax
0.759 0.241 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.757 0.243 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.757 0.243 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.756 0.243 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.754 0.246 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.751 0.249 0.000
K82.4 Cholesterolosis of gallbladder
0.751 0.249 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.750 0.250 0.000
E83 Disorders of mineral metabolism
0.749 0.251 0.000
Y85 Sequelae of transport accidents
0.748 0.252 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.747 0.253 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.746 0.254 0.000
C51 Malignant neoplasm of vulva
0.745 0.255 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.745 0.255 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.745 0.255 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.744 0.256 0.000
L50-L54 Urticaria and erythema
0.743 0.257 0.000
J40 Bronchitis, not specified as acute or chronic
0.743 0.257 0.000
C43 Malignant melanoma of skin
0.742 0.258 0.000
H73 Other disorders of tympanic membrane
0.742 0.258 0.000
C79 Secondary malignant neoplasm of other sites
0.739 0.261 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.739 0.261 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.738 0.262 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.737 0.263 0.000
G70-G73 Diseases of myoneural junction and muscle
0.737 0.263 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.735 0.265 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.734 0.266 0.000
S42.2 Fracture of upper end of humerus
0.734 0.266 0.000
K63.1 Perforation of intestine (nontraumatic)
0.732 0.268 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.732 0.268 0.000
J98.9 Respiratory disorder, unspecified
0.730 0.270 0.000
X60-X84 Intentional self-harm
0.729 0.270 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.729 0.271 0.000
K85.9 Acute pancreatitis, unspecified
0.729 0.271 0.000
K76.9 Liver disease, unspecified
0.729 0.271 0.000
K74 Fibrosis and cirrhosis of liver
0.729 0.271 0.000
F10.1 Harmful use
0.728 0.272 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.728 0.272 0.000
S92 Fracture of foot, except ankle
0.728 0.272 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.727 0.273 0.000
C53.9 Cervix uteri, unspecified
0.726 0.274 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.724 0.276 0.000
Y52 Agents primarily affecting the cardiovascular system
0.724 0.276 0.000
T79-T79 Certain early complications of trauma
0.723 0.277 0.000
L27 Dermatitis due to substances taken internally
0.721 0.278 0.000
G60 Hereditary and idiopathic neuropathy
0.721 0.279 0.000
G37 Other demyelinating diseases of central nervous system
0.721 0.279 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.720 0.280 0.000
Chapter VII Diseases of the eye and adnexa
0.719 0.281 0.000
K61 Abscess of anal and rectal regions
0.718 0.282 0.000
D69.6 Thrombocytopenia, unspecified
0.718 0.282 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.283 0.000
Y43.4 Immunosuppressive agents
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.715 0.285 0.000
C77.9 Lymph node, unspecified
0.715 0.285 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.714 0.286 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.714 0.286 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.713 0.286 0.000
J41 Simple and mucopurulent chronic bronchitis
0.712 0.288 0.000
E40-E46 Malnutrition
0.712 0.288 0.000
Y57 Other and unspecified drugs and medicaments
0.712 0.288 0.000
I15 Secondary hypertension
0.710 0.290 0.000
I13 Hypertensive heart and renal disease
0.710 0.290 0.000
I11 Hypertensive heart disease
0.710 0.290 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.709 0.291 0.000
I25.6 Silent myocardial ischaemia
0.709 0.291 0.000
I25.4 Coronary artery aneurysm
0.709 0.291 0.000
I25.3 Aneurysm of heart
0.709 0.291 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.709 0.291 0.000
I27 Other pulmonary heart diseases
0.709 0.291 0.000
S91 Open wound of ankle and foot
0.708 0.291 0.000
E73 Lactose intolerance
0.708 0.292 0.000
J34.3 Hypertrophy of nasal turbinates
0.708 0.292 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.707 0.293 0.000
C66 Malignant neoplasm of ureter
0.707 0.293 0.000
C65 Malignant neoplasm of renal pelvis
0.707 0.293 0.000
E22 Hyperfunction of pituitary gland
0.707 0.293 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.706 0.294 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.706 0.294 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.706 0.294 0.000
T33-T35 Frostbite
0.705 0.294 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.705 0.294 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.705 0.294 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.705 0.294 0.000
T00-T07 Injuries involving multiple body regions
0.705 0.294 0.000
S10-S19 Injuries to the neck
0.705 0.294 0.000
I05-I09 Chronic rheumatic heart diseases
0.705 0.295 0.000
Y35-Y36 Legal intervention and operations of war
0.705 0.295 0.000
Y10-Y34 Event of undetermined intent
0.705 0.295 0.000
Y00-Y09 Assault
0.705 0.295 0.000
X85-X99 Assault
0.705 0.295 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.705 0.295 0.000
X50-X57 Overexertion, travel and privation
0.705 0.295 0.000
X30-X39 Exposure to forces of nature
0.705 0.295 0.000
X20-X29 Contact with venomous animals and plants
0.705 0.295 0.000
X10-X19 Contact with heat and hot substances
0.705 0.295 0.000
X00-X09 Exposure to smoke, fire and flames
0.705 0.295 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.705 0.295 0.000
W75-W84 Other accidental threats to breathing
0.705 0.295 0.000
W65-W74 Accidental drowning and submersion
0.705 0.295 0.000
W50-W64 Exposure to animate mechanical forces
0.705 0.295 0.000
V98-V99 Other and unspecified transport accidents
0.705 0.295 0.000
V95-V97 Air and space transport accidents
0.705 0.295 0.000
V90-V94 Water transport accidents
0.705 0.295 0.000
V80-V89 Other land transport accidents
0.705 0.295 0.000
V70-V79 Bus occupant injured in transport accident
0.705 0.295 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.705 0.295 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.705 0.295 0.000
V40-V49 Car occupant injured in transport accident
0.705 0.295 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.705 0.295 0.000
V20-V29 Motorcycle rider injured in transport accident
0.705 0.295 0.000
V01-V09 Pedestrian injured in transport accident
0.705 0.295 0.000
C77.1 Intrathoracic lymph nodes
0.704 0.295 0.000
D80-D89 Certain disorders involving the immune mechanism
0.704 0.296 0.000
J37 Chronic laryngitis and laryngotracheitis
0.704 0.296 0.000
K56.3 Gallstone ileus
0.700 0.299 0.000
K56.1 Intussusception
0.700 0.299 0.000
K56.0 Paralytic ileus
0.700 0.299 0.000
A49.0 Staphylococcal infection, unspecified
0.701 0.299 0.000
K86.9 Disease of pancreas, unspecified
0.700 0.300 0.000
C71.2 Temporal lobe
0.699 0.301 0.000
A04.8 Other specified bacterial intestinal infections
0.699 0.301 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.698 0.302 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.698 0.302 0.000
S40 Superficial injury of shoulder and upper arm
0.696 0.304 0.000
W00-W19 Falls
0.696 0.304 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.696 0.304 0.000
K85.1 Biliary acute pancreatitis
0.696 0.304 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.695 0.305 0.000
J94 Other pleural conditions
0.695 0.305 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.695 0.305 0.000
Y40 Systemic antibiotics
0.694 0.306 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.694 0.306 0.000
J96 Respiratory failure, not elsewhere classified
0.694 0.306 0.000
J43.9 Emphysema, unspecified
0.693 0.307 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.693 0.307 0.000
B99-B99 Other infectious diseases
0.692 0.308 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.692 0.308 0.000
B65-B83 Helminthiases
0.692 0.308 0.000
B50-B64 Protozoal diseases
0.692 0.308 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.692 0.308 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.692 0.308 0.000
A80-A89 Viral infections of the central nervous system
0.692 0.308 0.000
A75-A79 Rickettsioses
0.692 0.308 0.000
A70-A74 Other diseases caused by chlamydiae
0.692 0.308 0.000
A65-A69 Other spirochaetal diseases
0.692 0.308 0.000
A20-A28 Certain zoonotic bacterial diseases
0.692 0.308 0.000
A15-A19 Tuberculosis
0.692 0.308 0.000
I25.5 Ischaemic cardiomyopathy
0.692 0.308 0.000
L28 Lichen simplex chronicus and prurigo
0.691 0.308 0.000
B35-B49 Mycoses
0.691 0.309 0.000
B15-B19 Viral hepatitis
0.691 0.309 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.690 0.310 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.690 0.310 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.689 0.311 0.000
C58 Malignant neoplasm of placenta
0.689 0.311 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.689 0.311 0.000
C52 Malignant neoplasm of vagina
0.689 0.311 0.000
S42.1 Fracture of scapula
0.689 0.311 0.000
H74 Other disorders of middle ear and mastoid
0.689 0.311 0.000
C54 Malignant neoplasm of corpus uteri
0.689 0.311 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.687 0.313 0.000
H92 Otalgia and effusion of ear
0.685 0.315 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.684 0.316 0.000
C67.8 Overlapping lesion of bladder
0.683 0.316 0.000
C67.7 Urachus
0.683 0.316 0.000
C67.5 Bladder neck
0.683 0.316 0.000
C67.3 Anterior wall of bladder
0.683 0.316 0.000
C67.1 Dome of bladder
0.683 0.316 0.000
C67.0 Trigone of bladder
0.683 0.316 0.000
Y59 Other and unspecified vaccines and biological substances
0.683 0.317 0.000
Y58 Bacterial vaccines
0.683 0.317 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.683 0.317 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.683 0.317 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.683 0.317 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.683 0.317 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.683 0.317 0.000
Y48 Anaesthetics and therapeutic gases
0.683 0.317 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.683 0.317 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.683 0.317 0.000
Y44 Agents primarily affecting blood constituents
0.683 0.317 0.000
C18.9 Colon, unspecified
0.683 0.317 0.000
K81.1 Chronic cholecystitis
0.682 0.318 0.000
F10.0 Acute intoxication
0.682 0.318 0.000
K52 Other non-infective gastro-enteritis and colitis
0.682 0.318 0.000
H73.8 Other specified disorders of tympanic membrane
0.682 0.318 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.682 0.318 0.000
H60-H62 Diseases of external ear
0.681 0.319 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.681 0.319 0.000
K63.3 Ulcer of intestine
0.679 0.320 0.000
A41.8 Other specified septicaemia
0.678 0.322 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.678 0.322 0.000
E78.0 Pure hypercholesterolaemia
0.678 0.322 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.677 0.323 0.000
C21 Malignant neoplasm of anus and anal canal
0.677 0.323 0.000
C17 Malignant neoplasm of small intestine
0.677 0.323 0.000
C23 Malignant neoplasm of gallbladder
0.677 0.323 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.676 0.323 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.676 0.324 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.676 0.324 0.000
L57.0 Actinic keratosis
0.675 0.325 0.000
K51 Ulcerative colitis
0.675 0.325 0.000
S01.8 Open wound of other parts of head
0.675 0.325 0.000
J39.2 Other diseases of pharynx
0.675 0.325 0.000
H81 Disorders of vestibular function
0.674 0.326 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.673 0.327 0.000
A08 Viral and other specified intestinal infections
0.673 0.327 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.673 0.327 0.000
I12.9 Hypertensive renal disease without renal failure
0.672 0.328 0.000
J98.8 Other specified respiratory disorders
0.672 0.328 0.000
J98.6 Disorders of diaphragm
0.671 0.329 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.671 0.329 0.000
J98.3 Compensatory emphysema
0.671 0.329 0.000
J98.2 Interstitial emphysema
0.671 0.329 0.000
D45 Polycythaemia vera
0.671 0.329 0.000
I12.0 Hypertensive renal disease with renal failure
0.671 0.329 0.000
S02 Fracture of skull and facial bones
0.671 0.329 0.000
A48 Other bacterial diseases, not elsewhere classified
0.670 0.329 0.000
A44 Bartonellosis
0.670 0.329 0.000
A43 Nocardiosis
0.670 0.329 0.000
A42 Actinomycosis
0.670 0.329 0.000
A40 Streptococcal septicaemia
0.670 0.329 0.000
A39 Meningococcal infection
0.670 0.329 0.000
A37 Whooping cough
0.670 0.329 0.000
A36 Diphtheria
0.670 0.329 0.000
A32 Listeriosis
0.670 0.329 0.000
A31 Infection due to other mycobacteria
0.670 0.329 0.000
A30 Leprosy [Hansen's disease]
0.670 0.329 0.000
A46 Erysipelas
0.670 0.329 0.000
A38 Scarlet fever
0.670 0.329 0.000
A35 Other tetanus
0.670 0.329 0.000
A34 Obstetrical tetanus
0.670 0.329 0.000
A33 Tetanus neonatorum
0.670 0.329 0.000
G80 Infantile cerebral palsy
0.670 0.330 0.000
E88 Other metabolic disorders
0.669 0.331 0.000
S42.20 Fracture of upper end of humerus (closed)
0.669 0.331 0.000
S05 Injury of eye and orbit
0.668 0.332 0.000
J30 Vasomotor and allergic rhinitis
0.668 0.332 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.667 0.333 0.000
L10-L14 Bullous disorders
0.667 0.333 0.000
J35 Chronic diseases of tonsils and adenoids
0.666 0.334 0.000
E34 Other endocrine disorders
0.666 0.334 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.665 0.335 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.663 0.336 0.000
E87.3 Alkalosis
0.663 0.337 0.000
J93.8 Other pneumothorax
0.663 0.337 0.000
J93.0 Spontaneous tension pneumothorax
0.663 0.337 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.662 0.338 0.000
K86.8 Other specified diseases of pancreas
0.661 0.339 0.000
G20-G26 Extrapyramidal and movement disorders
0.658 0.342 0.000
K77 Liver disorders in diseases classified elsewhere
0.658 0.342 0.000
K73 Chronic hepatitis, not elsewhere classified
0.658 0.342 0.000
K71 Toxic liver disease
0.658 0.342 0.000
S20 Superficial injury of thorax
0.656 0.344 0.000
D00-D09 In situ neoplasms
0.655 0.345 0.000
A49.8 Other bacterial infections of unspecified site
0.654 0.346 0.000
Y89 Sequelae of other external causes
0.654 0.346 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.654 0.346 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.654 0.346 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.654 0.346 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.654 0.346 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.654 0.346 0.000
K63.4 Enteroptosis
0.653 0.347 0.000
K63.0 Abscess of intestine
0.653 0.347 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.653 0.347 0.000
T40.6 Other and unspecified narcotics
0.652 0.348 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.650 0.350 0.000
L43 Lichen planus
0.649 0.350 0.000
G40-G47 Episodic and paroxysmal disorders
0.649 0.351 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.649 0.351 0.000
K60.2 Anal fissure, unspecified
0.649 0.351 0.000
C15.4 Middle third of oesophagus
0.648 0.352 0.000
E21.0 Primary hyperparathyroidism
0.648 0.352 0.000
E85 Amyloidosis
0.648 0.352 0.000
E84 Cystic fibrosis
0.648 0.352 0.000
E79 Disorders of purine and pyrimidine metabolism
0.648 0.352 0.000
E77 Disorders of glycoprotein metabolism
0.648 0.352 0.000
E76 Disorders of glycosaminoglycan metabolism
0.648 0.352 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.648 0.352 0.000
E74 Other disorders of carbohydrate metabolism
0.648 0.352 0.000
E72 Other disorders of amino-acid metabolism
0.648 0.352 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.648 0.352 0.000
E70 Disorders of aromatic amino-acid metabolism
0.648 0.352 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.648 0.352 0.000
G83 Other paralytic syndromes
0.646 0.354 0.000
C77.3 Axillary and upper limb lymph nodes
0.646 0.354 0.000
Y88 Sequelae of surgical and medical care as external cause
0.645 0.354 0.000
K63.9 Disease of intestine, unspecified
0.645 0.355 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.645 0.355 0.000
S99 Other and unspecified injuries of ankle and foot
0.645 0.355 0.000
S98 Traumatic amputation of ankle and foot
0.645 0.355 0.000
S97 Crushing injury of ankle and foot
0.645 0.355 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.645 0.355 0.000
S95 Injury of blood vessels at ankle and foot level
0.645 0.355 0.000
S94 Injury of nerves at ankle and foot level
0.645 0.355 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.645 0.355 0.000
G64 Other disorders of peripheral nervous system
0.644 0.355 0.000
W22 Striking against or struck by other objects
0.644 0.356 0.000
J36 Peritonsillar abscess
0.644 0.356 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.644 0.356 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.643 0.357 0.000
K72 Hepatic failure, not elsewhere classified
0.643 0.357 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.642 0.358 0.000
S48 Traumatic amputation of shoulder and upper arm
0.642 0.358 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.642 0.358 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.642 0.358 0.000
S44 Injury of nerves at shoulder and upper arm level
0.642 0.358 0.000
S41 Open wound of shoulder and upper arm
0.642 0.358 0.000
S47 Crushing injury of shoulder and upper arm
0.642 0.358 0.000
F10.2 Dependence syndrome
0.642 0.358 0.000
F03 Unspecified dementia
0.642 0.358 0.000
K76.6 Portal hypertension
0.642 0.358 0.000
K56.4 Other impaction of intestine
0.641 0.358 0.000
E66 Obesity
0.641 0.359 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.641 0.359 0.000
S42.4 Fracture of lower end of humerus
0.640 0.360 0.000
C71.9 Brain, unspecified
0.639 0.361 0.000
H04 Disorders of lachrymal system
0.639 0.361 0.000
C25.2 Tail of pancreas
0.639 0.361 0.000
D75 Other diseases of blood and blood-forming organs
0.638 0.362 0.000
T40.2 Other opioids
0.638 0.362 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.637 0.363 0.000
C80.9 Malignant neoplasm, unspecified
0.636 0.364 0.000
I22 Subsequent myocardial infarction
0.635 0.365 0.000
D55-D59 Haemolytic anaemias
0.635 0.365 0.000
S01.1 Open wound of eyelid and periocular area
0.635 0.365 0.000
F60-F69 Disorders of adult personality and behaviour
0.635 0.365 0.000
A41.4 Septicaemia due to anaerobes
0.635 0.365 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.635 0.365 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.635 0.365 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.635 0.365 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.635 0.365 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.635 0.365 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.635 0.365 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.635 0.365 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.635 0.365 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.635 0.365 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.635 0.365 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.635 0.365 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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