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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73388874
log Bayes Factor = 13.8676
Chromosome 11   position 4,697,262  (GRCh37) Explore rs73388874 on Ensembl!
Variant rs73388874 is part of Cluster X0170

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.998 0.002 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.998 0.002 0.000
O60-O75 Complications of labour and delivery
0.996 0.004 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.995 0.005 0.000
Chapter VIII Diseases of the ear and mastoid process
0.994 0.006 0.000
I25 Chronic ischaemic heart disease
0.993 0.007 0.000
J09-J18 Influenza and pneumonia
0.991 0.009 0.000
Chapter XI Diseases of the digestive system
0.989 0.011 0.000
I25.2 Old myocardial infarction
0.988 0.012 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.985 0.015 0.000
J40-J47 Chronic lower respiratory diseases
0.983 0.017 0.000
J18 Pneumonia, organism unspecified
0.982 0.018 0.000
H65-H75 Diseases of middle ear and mastoid
0.982 0.018 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.979 0.021 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.976 0.024 0.000
K70-K77 Diseases of liver
0.972 0.028 0.000
J18.9 Pneumonia, unspecified
0.968 0.032 0.000
M50-M54 Other dorsopathies
0.967 0.033 0.000
O63 Long labour
0.950 0.050 0.000
M54 Dorsalgia
0.948 0.052 0.000
K81 Cholecystitis
0.944 0.056 0.000
Chapter VI Diseases of the nervous system
0.939 0.061 0.000
I24 Other acute ischaemic heart diseases
0.939 0.061 0.000
K76 Other diseases of liver
0.938 0.062 0.000
O70 Perineal laceration during delivery
0.933 0.067 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.927 0.073 0.000
J47 Bronchiectasis
0.921 0.079 0.000
I31 Other diseases of pericardium
0.921 0.079 0.000
H71 Cholesteatoma of middle ear
0.919 0.081 0.000
I42 Cardiomyopathy
0.917 0.083 0.000
K80 Cholelithiasis
0.915 0.085 0.000
Chapter XIV Diseases of the genitourinary system
0.908 0.092 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.896 0.104 0.000
O63.1 Prolonged second stage (of labour)
0.894 0.106 0.000
I35 Nonrheumatic aortic valve disorders
0.892 0.108 0.000
K55-K64 Other diseases of intestines
0.892 0.108 0.000
I50 Heart failure
0.888 0.112 0.000
K81.9 Cholecystitis, unspecified
0.885 0.115 0.000
K60 Fissure and fistula of anal and rectal regions
0.884 0.116 0.000
K76.9 Liver disease, unspecified
0.883 0.117 0.000
O70.0 First degree perineal laceration during delivery
0.881 0.119 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.880 0.120 0.000
Chapter I Certain infectious and parasitic diseases
0.879 0.121 0.000
M50 Cervical disk disorders
0.878 0.122 0.000
M54.9 Dorsalgia, unspecified
0.878 0.122 0.000
I05-I09 Chronic rheumatic heart diseases
0.877 0.123 0.000
D50-D53 Nutritional anaemias
0.876 0.124 0.000
K86 Other diseases of pancreas
0.872 0.128 0.000
S60-S69 Injuries to the wrist and hand
0.869 0.131 0.000
I47 Paroxysmal tachycardia
0.866 0.134 0.000
N20-N23 Urolithiasis
0.866 0.134 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.865 0.135 0.000
J18.1 Lobar pneumonia, unspecified
0.863 0.137 0.000
H73 Other disorders of tympanic membrane
0.859 0.141 0.000
M54.2 Cervicalgia
0.855 0.145 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.852 0.148 0.000
I24.8 Other forms of acute ischaemic heart disease
0.850 0.150 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.845 0.155 0.000
J40 Bronchitis, not specified as acute or chronic
0.845 0.155 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.845 0.155 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.841 0.159 0.000
K76.8 Other specified diseases of liver
0.839 0.161 0.000
J43 Emphysema
0.839 0.161 0.000
K60.2 Anal fissure, unspecified
0.839 0.161 0.000
O62 Abnormalities of forces of labour
0.838 0.162 0.000
H90-H95 Other disorders of ear
0.837 0.163 0.000
S40-S49 Injuries to the shoulder and upper arm
0.836 0.164 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.834 0.166 0.000
K81.0 Acute cholecystitis
0.834 0.166 0.000
I44 Atrioventricular and left bundle-branch block
0.834 0.166 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.833 0.167 0.000
I31.3 Pericardial effusion (noninflammatory)
0.831 0.169 0.000
K60.3 Anal fistula
0.831 0.169 0.000
N20 Calculus of kidney and ureter
0.831 0.169 0.000
D60-D64 Aplastic and other anaemias
0.830 0.170 0.000
Chapter II Neoplasms
0.828 0.172 0.000
I50.0 Congestive heart failure
0.825 0.175 0.000
K74 Fibrosis and cirrhosis of liver
0.821 0.179 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.820 0.180 0.000
J42 Unspecified chronic bronchitis
0.820 0.180 0.000
G20-G26 Extrapyramidal and movement disorders
0.818 0.182 0.000
O00-O08 Pregnancy with abortive outcome
0.816 0.184 0.000
M54.4 Lumbago with sciatica
0.813 0.187 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.810 0.190 0.000
H65 Nonsuppurative otitis media
0.810 0.190 0.000
H66 Suppurative and unspecified otitis media
0.809 0.191 0.000
Chapter XX External causes of morbidity and mortality
0.807 0.193 0.000
K82 Other diseases of gallbladder
0.806 0.194 0.000
I08 Multiple valve diseases
0.805 0.195 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.805 0.195 0.000
I34 Nonrheumatic mitral valve disorders
0.805 0.195 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.800 0.200 0.000
K85 Acute pancreatitis
0.799 0.200 0.000
I35.1 Aortic (valve) insufficiency
0.799 0.201 0.000
G90-G99 Other disorders of the nervous system
0.797 0.203 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.795 0.205 0.000
D55-D59 Haemolytic anaemias
0.795 0.205 0.000
O73 Retained placenta and membranes, without haemorrhage
0.794 0.206 0.000
H80-H83 Diseases of inner ear
0.794 0.206 0.000
M65-M68 Disorders of synovium and tendon
0.793 0.207 0.000
M20-M25 Other joint disorders
0.792 0.208 0.000
N25-N29 Other disorders of kidney and ureter
0.791 0.209 0.000
O63.0 Prolonged first stage (of labour)
0.791 0.209 0.000
I45 Other conduction disorders
0.790 0.210 0.000
J11 Influenza, virus not identified
0.790 0.210 0.000
M54.22 Cervicalgia (Cervical region)
0.789 0.211 0.000
I21 Acute myocardial infarction
0.787 0.213 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.785 0.215 0.000
H74 Other disorders of middle ear and mastoid
0.785 0.215 0.000
I42.2 Other hypertrophic cardiomyopathy
0.784 0.216 0.000
K61 Abscess of anal and rectal regions
0.783 0.217 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.782 0.218 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.778 0.222 0.000
N60-N64 Disorders of breast
0.777 0.223 0.000
I71 Aortic aneurysm and dissection
0.776 0.224 0.000
S70-S79 Injuries to the hip and thigh
0.776 0.224 0.000
K70 Alcoholic liver disease
0.773 0.227 0.000
M50.0 Cervical disk disorder with myelopathy
0.773 0.227 0.000
M70-M79 Other soft tissue disorders
0.773 0.227 0.000
H73.8 Other specified disorders of tympanic membrane
0.770 0.230 0.000
J44 Other chronic obstructive pulmonary disease
0.770 0.230 0.000
J60-J70 Lung diseases due to external agents
0.768 0.232 0.000
N20.1 Calculus of ureter
0.768 0.232 0.000
I25.5 Ischaemic cardiomyopathy
0.767 0.233 0.000
J95-J99 Other diseases of the respiratory system
0.764 0.236 0.000
O72 Postpartum haemorrhage
0.764 0.236 0.000
T39.1 4-Aminophenol derivatives
0.763 0.237 0.000
D50 Iron deficiency anaemia
0.763 0.237 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.760 0.240 0.000
I31.9 Disease of pericardium, unspecified
0.759 0.241 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.758 0.242 0.000
H60-H62 Diseases of external ear
0.758 0.242 0.000
S10-S19 Injuries to the neck
0.757 0.243 0.000
B35-B49 Mycoses
0.757 0.243 0.000
D80-D89 Certain disorders involving the immune mechanism
0.756 0.244 0.000
I95 Hypotension
0.756 0.244 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.752 0.248 0.000
T79-T79 Certain early complications of trauma
0.752 0.248 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.750 0.250 0.000
Chapter XXII Codes for special purposes
0.750 0.250 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.749 0.251 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.749 0.251 0.000
J00-J06 Acute upper respiratory infections
0.749 0.251 0.000
B95-B98 Bacterial, viral and other infectious agents
0.749 0.251 0.000
J46 Status asthmaticus
0.747 0.253 0.000
I47.2 Ventricular tachycardia
0.745 0.255 0.000
I20 Angina pectoris
0.743 0.257 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.743 0.257 0.000
O66 Other obstructed labour
0.742 0.258 0.000
I42.9 Cardiomyopathy, unspecified
0.742 0.258 0.000
S90-S99 Injuries to the ankle and foot
0.741 0.259 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.739 0.261 0.000
S20-S29 Injuries to the thorax
0.739 0.261 0.000
I33 Acute and subacute endocarditis
0.738 0.262 0.000
J43.9 Emphysema, unspecified
0.736 0.264 0.000
G30-G32 Other degenerative diseases of the nervous system
0.736 0.264 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.735 0.265 0.000
I30 Acute pericarditis
0.734 0.266 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.734 0.266 0.000
S80-S89 Injuries to the knee and lower leg
0.733 0.267 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.733 0.267 0.000
G20 Parkinson's disease
0.732 0.268 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.732 0.268 0.000
C51-C58 Malignant neoplasms of female genital organs
0.727 0.273 0.000
T92 Sequelae of injuries of upper limb
0.727 0.273 0.000
S42 Fracture of shoulder and upper arm
0.727 0.273 0.000
O62.2 Other uterine inertia
0.725 0.275 0.000
K86.8 Other specified diseases of pancreas
0.725 0.275 0.000
M91-M94 Chondropathies
0.724 0.275 0.000
I22 Subsequent myocardial infarction
0.724 0.276 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.723 0.277 0.000
M53 Other dorsopathies, not elsewhere classified
0.722 0.278 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.722 0.278 0.000
C91 Lymphoid leukaemia
0.720 0.280 0.000
K72 Hepatic failure, not elsewhere classified
0.720 0.280 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.717 0.283 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.717 0.283 0.000
D70 Agranulocytosis
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I36 Nonrheumatic tricuspid valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
O85-O92 Complications predominantly related to the puerperium
0.715 0.285 0.000
G58 Other mononeuropathies
0.714 0.286 0.000
I49 Other cardiac arrhythmias
0.714 0.286 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.714 0.286 0.000
O74 Complications of anaesthesia during labour and delivery
0.714 0.286 0.000
O71 Other obstetric trauma
0.714 0.286 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.714 0.286 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.714 0.286 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.714 0.286 0.000
O61 Failed induction of labour
0.714 0.286 0.000
O60 Preterm delivery
0.714 0.286 0.000
H90 Conductive and sensorineural hearing loss
0.713 0.287 0.000
T33-T35 Frostbite
0.713 0.287 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.287 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.713 0.287 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.287 0.000
O70.2 Third degree perineal laceration during delivery
0.713 0.287 0.000
K60.1 Chronic anal fissure
0.713 0.287 0.000
I42.0 Dilated cardiomyopathy
0.712 0.288 0.000
I25.6 Silent myocardial ischaemia
0.712 0.288 0.000
I25.4 Coronary artery aneurysm
0.712 0.288 0.000
I25.3 Aneurysm of heart
0.712 0.288 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.712 0.288 0.000
G70-G73 Diseases of myoneural junction and muscle
0.712 0.288 0.000
M40-M43 Deforming dorsopathies
0.711 0.289 0.000
J17 Pneumonia in diseases classified elsewhere
0.710 0.289 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.710 0.289 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.710 0.289 0.000
J12 Viral pneumonia, not elsewhere classified
0.710 0.289 0.000
J10 Influenza due to identified influenza virus
0.710 0.289 0.000
J14 Pneumonia due to Haemophilus influenzae
0.710 0.289 0.000
J09 Influenza due to certain identified influenza virus
0.710 0.289 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.710 0.290 0.000
M50.1 Cervical disk disorder with radiculopathy
0.710 0.290 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.709 0.291 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.708 0.292 0.000
J18.0 Bronchopneumonia, unspecified
0.708 0.292 0.000
M54.5 Low back pain
0.706 0.294 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.706 0.294 0.000
I44.3 Other and unspecified atrioventricular block
0.706 0.294 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.706 0.294 0.000
J41 Simple and mucopurulent chronic bronchitis
0.705 0.295 0.000
J18.8 Other pneumonia, organism unspecified
0.704 0.296 0.000
J18.2 Hypostatic pneumonia, unspecified
0.704 0.296 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.704 0.296 0.000
H70 Mastoiditis and related conditions
0.704 0.296 0.000
H69 Other disorders of Eustachian tube
0.704 0.296 0.000
H68 Eustachian salpingitis and obstruction
0.704 0.296 0.000
H67 Otitis media in diseases classified elsewhere
0.704 0.296 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.704 0.296 0.000
I51 Complications and ill-defined descriptions of heart disease
0.703 0.296 0.000
T66-T78 Other and unspecified effects of external causes
0.703 0.297 0.000
M60-M63 Disorders of muscles
0.702 0.298 0.000
M00-M03 Infectious arthropathies
0.702 0.298 0.000
K61.0 Anal abscess
0.702 0.298 0.000
S62 Fracture at wrist and hand level
0.700 0.300 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.700 0.300 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.699 0.301 0.000
I08.0 Disorders of both mitral and aortic valves
0.697 0.303 0.000
K77 Liver disorders in diseases classified elsewhere
0.697 0.303 0.000
K75 Other inflammatory liver diseases
0.697 0.303 0.000
K73 Chronic hepatitis, not elsewhere classified
0.697 0.303 0.000
K71 Toxic liver disease
0.697 0.303 0.000
X60-X84 Intentional self-harm
0.695 0.305 0.000
K74.6 Other and unspecified cirrhosis of liver
0.695 0.305 0.000
K55 Vascular disorders of intestine
0.695 0.305 0.000
I44.7 Left bundle-branch block, unspecified
0.694 0.306 0.000
M65 Synovitis and tenosynovitis
0.694 0.306 0.000
D51 Vitamin B12 deficiency anaemia
0.693 0.306 0.000
S32 Fracture of lumbar spine and pelvis
0.693 0.307 0.000
M80-M85 Disorders of bone density and structure
0.691 0.309 0.000
K86.2 Cyst of pancreas
0.688 0.312 0.000
J90-J94 Other diseases of pleura
0.688 0.312 0.000
N73 Other female pelvic inflammatory diseases
0.687 0.313 0.000
G56 Mononeuropathies of upper limb
0.686 0.314 0.000
N21 Calculus of lower urinary tract
0.686 0.314 0.000
H92 Otalgia and effusion of ear
0.685 0.315 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.685 0.315 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.685 0.315 0.000
K62 Other diseases of anus and rectum
0.683 0.317 0.000
K82.8 Other specified diseases of gallbladder
0.682 0.318 0.000
O63.9 Long labour, unspecified
0.681 0.319 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.681 0.319 0.000
K76.6 Portal hypertension
0.681 0.319 0.000
K85.9 Acute pancreatitis, unspecified
0.681 0.319 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.680 0.319 0.000
D75 Other diseases of blood and blood-forming organs
0.680 0.320 0.000
M54.8 Other dorsalgia
0.680 0.320 0.000
M54.6 Pain in thoracic spine
0.680 0.320 0.000
M54.0 Panniculitis affecting regions of neck and back
0.680 0.320 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.679 0.321 0.000
M50.3 Other cervical disk degeneration
0.679 0.321 0.000
M86-M90 Other osteopathies
0.678 0.322 0.000
K81.8 Other cholecystitis
0.677 0.323 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.677 0.323 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.676 0.324 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.676 0.324 0.000
H66.3 Other chronic suppurative otitis media
0.675 0.325 0.000
I34.0 Mitral (valve) insufficiency
0.675 0.325 0.000
K86.9 Disease of pancreas, unspecified
0.675 0.325 0.000
O02 Other abnormal products of conception
0.675 0.325 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.674 0.326 0.000
I47.1 Supraventricular tachycardia
0.674 0.326 0.000
M24 Other specific joint derangements
0.674 0.326 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.674 0.326 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.674 0.326 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.673 0.327 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.673 0.327 0.000
I24.1 Dressler's syndrome
0.673 0.327 0.000
K76.7 Hepatorenal syndrome
0.673 0.327 0.000
K76.5 Hepatic veno-occlusive disease
0.673 0.327 0.000
K76.4 Peliosis hepatis
0.673 0.327 0.000
K76.3 Infarction of liver
0.673 0.327 0.000
K76.2 Central haemorrhagic necrosis of liver
0.673 0.327 0.000
K76.1 Chronic passive congestion of liver
0.673 0.327 0.000
S00-S09 Injuries to the head
0.673 0.327 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.671 0.329 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.671 0.329 0.000
N10-N16 Renal tubulo-interstitial diseases
0.671 0.329 0.000
N20.0 Calculus of kidney
0.670 0.330 0.000
O75.8 Other specified complications of labour and delivery
0.669 0.330 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.669 0.331 0.000
K80.4 Calculus of bile duct with cholecystitis
0.669 0.331 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.669 0.331 0.000
N99-N99 Other disorders of the genitourinary system
0.669 0.331 0.000
O70.9 Perineal laceration during delivery, unspecified
0.669 0.331 0.000
O70.3 Fourth degree perineal laceration during delivery
0.669 0.331 0.000
S64 Injury of nerves at wrist and hand level
0.669 0.331 0.000
H72 Perforation of tympanic membrane
0.668 0.332 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.666 0.334 0.000
C91.1 Chronic lymphocytic leukaemia
0.666 0.334 0.000
D59 Acquired haemolytic anaemia
0.665 0.335 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.665 0.335 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.664 0.335 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.664 0.335 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.664 0.335 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.664 0.335 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.664 0.335 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.664 0.335 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.664 0.335 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.664 0.335 0.000
T36 Poisoning by systemic antibiotics
0.664 0.335 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.663 0.337 0.000
A00-A09 Intestinal infectious diseases
0.663 0.337 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.662 0.338 0.000
D52 Folate deficiency anaemia
0.662 0.338 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.662 0.338 0.000
L40-L45 Papulosquamous disorders
0.662 0.338 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.661 0.338 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.661 0.339 0.000
S60 Superficial injury of wrist and hand
0.661 0.339 0.000
D62 Acute posthaemorrhagic anaemia
0.661 0.339 0.000
C56 Malignant neoplasm of ovary
0.661 0.339 0.000
T90 Sequelae of injuries of head
0.661 0.339 0.000
I31.8 Other specified diseases of pericardium
0.660 0.340 0.000
I31.2 Haemopericardium, not elsewhere classified
0.660 0.340 0.000
I31.1 Chronic constrictive pericarditis
0.660 0.340 0.000
I31.0 Chronic adhesive pericarditis
0.660 0.340 0.000
K58 Irritable bowel syndrome
0.660 0.340 0.000
S42.2 Fracture of upper end of humerus
0.660 0.340 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.659 0.341 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.659 0.341 0.000
I42.8 Other cardiomyopathies
0.657 0.343 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.657 0.343 0.000
I42.6 Alcoholic cardiomyopathy
0.657 0.343 0.000
I42.5 Other restrictive cardiomyopathy
0.657 0.343 0.000
I42.4 Endocardial fibroelastosis
0.657 0.343 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.657 0.343 0.000
N20.2 Calculus of kidney with calculus of ureter
0.656 0.344 0.000
M54.3 Sciatica
0.656 0.344 0.000
K80.3 Calculus of bile duct with cholangitis
0.656 0.344 0.000
K80.8 Other cholelithiasis
0.656 0.344 0.000
O70.1 Second degree perineal laceration during delivery
0.655 0.345 0.000
M22 Disorders of patella
0.652 0.348 0.000
I21.9 Acute myocardial infarction, unspecified
0.652 0.348 0.000
I20.0 Unstable angina
0.652 0.348 0.000
N63 Unspecified lump in breast
0.651 0.349 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.650 0.350 0.000
H81 Disorders of vestibular function
0.650 0.350 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.649 0.351 0.000
O73.0 Retained placenta, without haemorrhage
0.649 0.351 0.000
O36 Maternal care for other known or suspected foetal problems
0.649 0.351 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.648 0.352 0.000
G93 Other disorders of brain
0.648 0.352 0.000
C92 Myeloid leukaemia
0.648 0.352 0.000
H65.4 Other chronic nonsuppurative otitis media
0.647 0.352 0.000
N20.9 Urinary calculus, unspecified
0.646 0.354 0.000
K86.1 Other chronic pancreatitis
0.646 0.354 0.000
J11.1 Influenza with other respiratory manifestations, virus not identified
0.645 0.355 0.000
D61 Other aplastic anaemias
0.644 0.356 0.000
I51.8 Other ill-defined heart diseases
0.643 0.356 0.000
H74.4 Polyp of middle ear
0.643 0.357 0.000
N00-N08 Glomerular diseases
0.643 0.357 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.643 0.357 0.000
B37 Candidiasis
0.643 0.357 0.000
N28.1 Cyst of kidney, acquired
0.641 0.359 0.000
K62.9 Disease of anus and rectum, unspecified
0.640 0.360 0.000
D50.8 Other iron deficiency anaemias
0.640 0.360 0.000
I35.9 Aortic valve disorder, unspecified
0.640 0.360 0.000
I35.8 Other aortic valve disorders
0.640 0.360 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.639 0.360 0.000
G91 Hydrocephalus
0.639 0.361 0.000
I50.9 Heart failure, unspecified
0.639 0.361 0.000
M54.1 Radiculopathy
0.638 0.361 0.000
K62.0 Anal polyp
0.638 0.362 0.000
K50-K52 Noninfective enteritis and colitis
0.638 0.362 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.638 0.362 0.000
S69 Other and unspecified injuries of wrist and hand
0.637 0.363 0.000
I46 Cardiac arrest
0.637 0.363 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.635 0.364 0.000
I95.9 Hypotension, unspecified
0.635 0.365 0.000
O80-O84 Delivery
0.635 0.365 0.000
O72.0 Third-stage haemorrhage
0.635 0.365 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.635 0.365 0.000
O42 Premature rupture of membranes
0.634 0.366 0.000
K81.1 Chronic cholecystitis
0.634 0.366 0.000
K60.5 Anorectal fistula
0.633 0.366 0.000
K60.4 Rectal fistula
0.633 0.366 0.000
K60.0 Acute anal fissure
0.633 0.366 0.000
Y43 Primarily systemic agents
0.633 0.367 0.000
C88 Malignant immunoproliferative diseases
0.632 0.368 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.632 0.368 0.000
M45-M49 Spondylopathies
0.631 0.369 0.000
I99 Other and unspecified disorders of circulatory system
0.631 0.369 0.000
D63.0 Anaemia in neoplastic disease
0.631 0.369 0.000
B99-B99 Other infectious diseases
0.630 0.370 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.630 0.370 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.630 0.370 0.000
B65-B83 Helminthiases
0.630 0.370 0.000
B50-B64 Protozoal diseases
0.630 0.370 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.630 0.370 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.630 0.370 0.000
A80-A89 Viral infections of the central nervous system
0.630 0.370 0.000
A75-A79 Rickettsioses
0.630 0.370 0.000
A70-A74 Other diseases caused by chlamydiae
0.630 0.370 0.000
A65-A69 Other spirochaetal diseases
0.630 0.370 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.630 0.370 0.000
A20-A28 Certain zoonotic bacterial diseases
0.630 0.370 0.000
A15-A19 Tuberculosis
0.630 0.370 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.630 0.370 0.000
G57 Mononeuropathies of lower limb
0.630 0.370 0.000
M50.9 Cervical disk disorder, unspecified
0.629 0.370 0.000
M50.8 Other cervical disk disorders
0.629 0.370 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.629 0.371 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.629 0.371 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.629 0.371 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.629 0.371 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.629 0.371 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.629 0.371 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.629 0.371 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.629 0.371 0.000
K82.9 Disease of gallbladder, unspecified
0.629 0.371 0.000
I09 Other rheumatic heart diseases
0.628 0.371 0.000
I06 Rheumatic aortic valve diseases
0.628 0.371 0.000
I05 Rheumatic mitral valve diseases
0.628 0.371 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.628 0.372 0.000
D00-D09 In situ neoplasms
0.628 0.372 0.000
D53 Other nutritional anaemias
0.628 0.372 0.000
J03 Acute tonsillitis
0.627 0.372 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.627 0.373 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.627 0.373 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.627 0.373 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.626 0.373 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.626 0.373 0.000
D45 Polycythaemia vera
0.626 0.373 0.000
S68 Traumatic amputation of wrist and hand
0.626 0.374 0.000
K86.3 Pseudocyst of pancreas
0.625 0.374 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.625 0.374 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.625 0.375 0.000
H80 Otosclerosis
0.624 0.376 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.624 0.376 0.000
S67 Crushing injury of wrist and hand
0.623 0.377 0.000
S65 Injury of blood vessels at wrist and hand level
0.623 0.377 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.621 0.379 0.000
I47.0 Reentry ventricular arrhythmia
0.621 0.379 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.621 0.379 0.000
K74.3 Primary biliary cirrhosis
0.621 0.379 0.000
G50 Disorders of trigeminal nerve
0.621 0.379 0.000
O03 Spontaneous abortion
0.620 0.379 0.000
G54 Nerve root and plexus disorders
0.620 0.380 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.620 0.380 0.000
G52 Disorders of other cranial nerves
0.620 0.380 0.000
S72 Fracture of femur
0.619 0.381 0.000
N62 Hypertrophy of breast
0.618 0.382 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.618 0.382 0.000
K70.0 Alcoholic fatty liver
0.617 0.383 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.617 0.383 0.000
M54.59 Low back pain (Site unspecified)
0.617 0.383 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.616 0.384 0.000
D37.4 Colon
0.616 0.384 0.000
H73.9 Disorder of tympanic membrane, unspecified
0.616 0.384 0.000
H73.1 Chronic myringitis
0.616 0.384 0.000
H73.0 Acute myringitis
0.616 0.384 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.615 0.385 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.615 0.385 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.614 0.385 0.000
I45.1 Other and unspecified right bundle-branch block
0.614 0.386 0.000
N73.6 Female pelvic peritoneal adhesions
0.614 0.386 0.000
M54.29 Cervicalgia-Site unspe
0.613 0.387 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.613 0.387 0.000
M54.27 Cervicalgia-Lumbosacral
0.613 0.387 0.000
M54.26 Cervicalgia-Lumbar
0.613 0.387 0.000
M54.25 Cervicalgia-Thoracolumbar
0.613 0.387 0.000
M54.24 Cervicalgia-Thoracic
0.613 0.387 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.613 0.387 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.613 0.387 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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