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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs73725220
log Bayes Factor = 7.2576
Chromosome 6   position 16,700,060  (GRCh37) Explore rs73725220 on Ensembl!
Variant rs73725220 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
0.998 0.002 0.000
M20-M25 Other joint disorders
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
H25-H28 Disorders of lens
0.993 0.007 0.000
H26 Other cataract
0.989 0.011 0.000
H26.9 Cataract, unspecified
0.985 0.015 0.000
M06 Other rheumatoid arthritis
0.985 0.015 0.000
Chapter VI Diseases of the nervous system
0.984 0.016 0.000
M20 Acquired deformities of fingers and toes
0.983 0.017 0.000
Chapter II Neoplasms
0.974 0.026 0.000
M06.9 Rheumatoid arthritis, unspecified
0.973 0.027 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.967 0.033 0.000
Chapter V Mental and behavioural disorders
0.964 0.036 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.959 0.041 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.955 0.045 0.000
M50-M54 Other dorsopathies
0.954 0.046 0.000
G90-G99 Other disorders of the nervous system
0.951 0.049 0.000
Chapter VIII Diseases of the ear and mastoid process
0.947 0.053 0.000
M13 Other arthritis
0.944 0.056 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.944 0.056 0.000
L60-L75 Disorders of skin appendages
0.940 0.060 0.000
M20.5 Other deformities of toe(s) (acquired)
0.926 0.074 0.000
M20.1 Hallux valgus (acquired)
0.922 0.078 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.922 0.078 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.912 0.088 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.907 0.093 0.000
M13.9 Arthritis, unspecified
0.906 0.094 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.888 0.112 0.000
L60 Nail disorders
0.887 0.113 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.885 0.115 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.884 0.116 0.000
D70 Agranulocytosis
0.882 0.118 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.882 0.118 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.877 0.123 0.000
C50-C50 Malignant neoplasm of breast
0.874 0.126 0.000
M54 Dorsalgia
0.872 0.128 0.000
F41 Other anxiety disorders
0.870 0.130 0.000
M50 Cervical disk disorders
0.866 0.134 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.860 0.140 0.000
H55-H59 Other disorders of eye and adnexa
0.854 0.146 0.000
M40-M43 Deforming dorsopathies
0.853 0.147 0.000
L60.0 Ingrowing nail
0.850 0.150 0.000
M70-M79 Other soft tissue disorders
0.838 0.162 0.000
F41.9 Anxiety disorder, unspecified
0.835 0.165 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.834 0.166 0.000
C78.7 Secondary malignant neoplasm of liver
0.830 0.170 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.828 0.172 0.000
M05 Seropositive rheumatoid arthritis
0.827 0.173 0.000
M35 Other systemic involvement of connective tissue
0.822 0.178 0.000
M25 Other joint disorders, not elsewhere classified
0.818 0.182 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.815 0.185 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.814 0.186 0.000
D69 Purpura and other haemorrhagic conditions
0.812 0.188 0.000
M50.1 Cervical disk disorder with radiculopathy
0.807 0.193 0.000
M22 Disorders of patella
0.807 0.193 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.803 0.197 0.000
C50 Malignant neoplasm of breast
0.803 0.197 0.000
C79 Secondary malignant neoplasm of other sites
0.802 0.198 0.000
G91 Hydrocephalus
0.801 0.199 0.000
Chapter I Certain infectious and parasitic diseases
0.800 0.200 0.000
H90-H95 Other disorders of ear
0.799 0.201 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.798 0.202 0.000
Chapter IX Diseases of the circulatory system
0.797 0.203 0.000
L72.0 Epidermal cyst
0.797 0.203 0.000
G93 Other disorders of brain
0.797 0.203 0.000
M91-M94 Chondropathies
0.795 0.205 0.000
H60-H62 Diseases of external ear
0.792 0.208 0.000
M23 Internal derangement of knee
0.792 0.208 0.000
M34 Systemic sclerosis
0.783 0.217 0.000
G95 Other diseases of spinal cord
0.781 0.219 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.778 0.222 0.000
H80-H83 Diseases of inner ear
0.775 0.225 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.772 0.228 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.771 0.229 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.770 0.230 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.767 0.233 0.000
M06.0 Seronegative rheumatoid arthritis
0.767 0.233 0.000
H26.4 After-cataract
0.765 0.235 0.000
M31 Other necrotising vasculopathies
0.764 0.236 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.764 0.236 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.763 0.236 0.000
H65-H75 Diseases of middle ear and mastoid
0.762 0.238 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.762 0.238 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.761 0.239 0.000
M24 Other specific joint derangements
0.761 0.239 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.760 0.240 0.000
M54.9 Dorsalgia, unspecified
0.755 0.245 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.754 0.246 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.754 0.246 0.000
M20.4 Other hammer toe(s) (acquired)
0.749 0.251 0.000
H25 Senile cataract
0.749 0.251 0.000
M10 Gout
0.747 0.253 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.745 0.255 0.000
H43-H45 Disorders of vitreous body and globe
0.745 0.255 0.000
C50.9 Breast, unspecified
0.744 0.256 0.000
D69.6 Thrombocytopenia, unspecified
0.743 0.257 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.742 0.258 0.000
M80-M85 Disorders of bone density and structure
0.738 0.262 0.000
M11 Other crystal arthropathies
0.736 0.264 0.000
H10-H13 Disorders of conjunctiva
0.735 0.265 0.000
M86-M90 Other osteopathies
0.734 0.266 0.000
C80 Malignant neoplasm without specification of site
0.730 0.270 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.730 0.270 0.000
H55 Nystagmus and other irregular eye movements
0.729 0.271 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.722 0.278 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.721 0.279 0.000
C78.0 Secondary malignant neoplasm of lung
0.721 0.279 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
G30-G32 Other degenerative diseases of the nervous system
0.717 0.283 0.000
M14 Arthropathies in other diseases classified elsewhere
0.716 0.284 0.000
M12 Other specific arthropathies
0.716 0.284 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.716 0.284 0.000
M08 Juvenile arthritis
0.716 0.284 0.000
M07 Psoriatic and enteropathic arthropathies
0.716 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.715 0.284 0.000
M33 Dermatopolymyositis
0.715 0.284 0.000
M32 Systemic lupus erythematosus
0.715 0.284 0.000
M30 Polyarteritis nodosa and related conditions
0.715 0.284 0.000
M21 Other acquired deformities of limbs
0.715 0.284 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.715 0.284 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.715 0.284 0.000
C64-C68 Malignant neoplasms of urinary tract
0.715 0.285 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.714 0.286 0.000
D00-D09 In situ neoplasms
0.713 0.287 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.712 0.288 0.000
H27 Other disorders of lens
0.712 0.288 0.000
M65-M68 Disorders of synovium and tendon
0.709 0.291 0.000
H26.3 Drug-induced cataract
0.709 0.291 0.000
H26.2 Complicated cataract
0.709 0.291 0.000
H26.1 Traumatic cataract
0.709 0.291 0.000
H26.0 Infantile, juvenile and presenile cataract
0.709 0.291 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.709 0.291 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.707 0.293 0.000
M06.8 Other specified rheumatoid arthritis
0.706 0.294 0.000
M06.4 Inflammatory polyarthropathy
0.706 0.294 0.000
M06.3 Rheumatoid nodule
0.706 0.294 0.000
M06.2 Rheumatoid bursitis
0.706 0.294 0.000
M06.1 Adult-onset Still's disease
0.706 0.294 0.000
M20.2 Hallux rigidus
0.706 0.294 0.000
G70-G73 Diseases of myoneural junction and muscle
0.706 0.294 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.706 0.294 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.706 0.294 0.000
D80-D89 Certain disorders involving the immune mechanism
0.705 0.295 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.705 0.295 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.705 0.295 0.000
M20.3 Other deformity of hallux (acquired)
0.705 0.295 0.000
M20.0 Deformity of finger(s)
0.705 0.295 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.704 0.295 0.000
H53-H54 Visual disturbances and blindness
0.703 0.297 0.000
H26.8 Other specified cataract
0.702 0.298 0.000
M54.2 Cervicalgia
0.699 0.301 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.698 0.301 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.698 0.301 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.698 0.301 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.698 0.301 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.697 0.302 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.697 0.302 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.697 0.302 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.697 0.302 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.697 0.302 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.697 0.302 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.697 0.302 0.000
I83 Varicose veins of lower extremities
0.696 0.304 0.000
M43 Other deforming dorsopathies
0.695 0.305 0.000
H04 Disorders of lachrymal system
0.695 0.305 0.000
D75 Other diseases of blood and blood-forming organs
0.695 0.305 0.000
G91.9 Hydrocephalus, unspecified
0.694 0.306 0.000
D55-D59 Haemolytic anaemias
0.693 0.307 0.000
M79.0 Rheumatism, unspecified
0.692 0.308 0.000
F99-F99 Unspecified mental disorder
0.691 0.309 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.691 0.309 0.000
F80-F89 Disorders of psychological development
0.691 0.309 0.000
F70-F79 Mental retardation
0.691 0.309 0.000
F60-F69 Disorders of adult personality and behaviour
0.691 0.309 0.000
G57 Mononeuropathies of lower limb
0.691 0.309 0.000
M41 Scoliosis
0.691 0.309 0.000
H40-H42 Glaucoma
0.690 0.310 0.000
M54.3 Sciatica
0.689 0.311 0.000
I27 Other pulmonary heart diseases
0.688 0.312 0.000
C44 Other malignant neoplasms of skin
0.687 0.313 0.000
S00-S09 Injuries to the head
0.687 0.313 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.686 0.313 0.000
L10-L14 Bullous disorders
0.684 0.315 0.000
M53 Other dorsopathies, not elsewhere classified
0.684 0.316 0.000
F10.1 Harmful use
0.682 0.318 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.682 0.318 0.000
G96 Other disorders of central nervous system
0.682 0.318 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.682 0.318 0.000
G90 Disorders of autonomic nervous system
0.682 0.318 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.682 0.318 0.000
G92 Toxic encephalopathy
0.682 0.318 0.000
D60-D64 Aplastic and other anaemias
0.682 0.318 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.681 0.319 0.000
D73 Diseases of spleen
0.681 0.319 0.000
L50-L54 Urticaria and erythema
0.681 0.319 0.000
G40-G47 Episodic and paroxysmal disorders
0.680 0.320 0.000
M13.8 Other specified arthritis
0.677 0.323 0.000
M13.1 Monoarthritis, not elsewhere classified
0.677 0.323 0.000
M13.0 Polyarthritis, unspecified
0.677 0.323 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.677 0.323 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.677 0.323 0.000
H61 Other disorders of external ear
0.677 0.323 0.000
H91 Other hearing loss
0.677 0.323 0.000
C15-C26 Malignant neoplasms of digestive organs
0.674 0.326 0.000
L75 Apocrine sweat disorders
0.674 0.326 0.000
L74 Eccrine sweat disorders
0.674 0.326 0.000
L73 Other follicular disorders
0.674 0.326 0.000
L71 Rosacea
0.674 0.326 0.000
L70 Acne
0.674 0.326 0.000
L68 Hypertrichosis
0.674 0.326 0.000
L67 Hair colour and hair shaft abnormalities
0.674 0.326 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.674 0.326 0.000
L65 Other nonscarring hair loss
0.674 0.326 0.000
L64 Androgenic alopecia
0.674 0.326 0.000
L63 Alopecia areata
0.674 0.326 0.000
L62 Nail disorders in diseases classified elsewhere
0.674 0.326 0.000
G20-G26 Extrapyramidal and movement disorders
0.673 0.327 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.672 0.328 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.671 0.329 0.000
I80 Phlebitis and thrombophlebitis
0.671 0.329 0.000
Chapter XX External causes of morbidity and mortality
0.667 0.333 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.667 0.333 0.000
M35.3 Polymyalgia rheumatica
0.666 0.334 0.000
H50 Other strabismus
0.665 0.335 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.662 0.338 0.000
B95-B98 Bacterial, viral and other infectious agents
0.662 0.338 0.000
M50.0 Cervical disk disorder with myelopathy
0.661 0.339 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.661 0.339 0.000
D74 Methaemoglobinaemia
0.661 0.339 0.000
D72 Other disorders of white blood cells
0.661 0.339 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.661 0.339 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.661 0.339 0.000
F10.3 Withdrawal state
0.661 0.339 0.000
G95.2 Cord compression, unspecified
0.659 0.341 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.659 0.341 0.000
M72 Fibroblastic disorders
0.658 0.342 0.000
C43 Malignant melanoma of skin
0.655 0.345 0.000
G58 Other mononeuropathies
0.654 0.346 0.000
G54 Nerve root and plexus disorders
0.654 0.346 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.654 0.346 0.000
G52 Disorders of other cranial nerves
0.654 0.346 0.000
G50 Disorders of trigeminal nerve
0.654 0.346 0.000
H57 Other disorders of eye and adnexa
0.654 0.346 0.000
I26 Pulmonary embolism
0.654 0.346 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.653 0.347 0.000
M22.8 Other disorders of patella
0.651 0.349 0.000
F48 Other neurotic disorders
0.650 0.350 0.000
F45 Somatoform disorders
0.650 0.350 0.000
F44 Dissociative [conversion] disorders
0.650 0.350 0.000
F43 Reaction to severe stress, and adjustment disorders
0.650 0.350 0.000
F42 Obsessive-compulsive disorder
0.650 0.350 0.000
C44.7 Skin of lower limb, including hip
0.650 0.350 0.000
M13.98 Arthritis, unspecified (Other)
0.649 0.350 0.000
M13.93 Arthritis, unspecified (Forearm)
0.649 0.350 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.649 0.350 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.649 0.351 0.000
M94 Other disorders of cartilage
0.648 0.352 0.000
H30-H36 Disorders of choroid and retina
0.646 0.354 0.000
M54.4 Lumbago with sciatica
0.646 0.354 0.000
C77.3 Axillary and upper limb lymph nodes
0.645 0.355 0.000
B25-B34 Other viral diseases
0.641 0.359 0.000
M54.1 Radiculopathy
0.641 0.359 0.000
M79.6 Pain in limb
0.641 0.359 0.000
M23.4 Loose body in knee
0.641 0.359 0.000
L20-L30 Dermatitis and eczema
0.640 0.360 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.639 0.361 0.000
G93.0 Cerebral cysts
0.639 0.361 0.000
G93.3 Postviral fatigue syndrome
0.638 0.362 0.000
C50.8 Overlapping lesion of breast
0.637 0.363 0.000
L60.9 Nail disorder, unspecified
0.636 0.364 0.000
L60.8 Other nail disorders
0.636 0.364 0.000
L60.5 Yellow nail syndrome
0.636 0.364 0.000
L60.4 Beau's lines
0.636 0.364 0.000
L60.3 Nail dystrophy
0.636 0.364 0.000
L60.2 Onychogryphosis
0.636 0.364 0.000
L60.1 Onycholysis
0.636 0.364 0.000
M35.0 Sicca syndrome [Sjogren]
0.635 0.365 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.635 0.365 0.000
D46 Myelodysplastic syndromes
0.635 0.365 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.634 0.366 0.000
L72.2 Steatocystoma multiplex
0.634 0.366 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.634 0.366 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.634 0.366 0.000
M25.8 Other specified joint disorders
0.633 0.366 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.632 0.368 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.632 0.368 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.632 0.368 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.632 0.368 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.632 0.368 0.000
C50.3 Lower-inner quadrant of breast
0.632 0.368 0.000
M25.5 Pain in joint
0.631 0.369 0.000
M34.9 Systemic sclerosis, unspecified
0.629 0.371 0.000
D68 Other coagulation defects
0.629 0.371 0.000
D67 Hereditary factor IX deficiency
0.629 0.371 0.000
D66 Hereditary factor VIII deficiency
0.629 0.371 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.629 0.371 0.000
F40 Phobic anxiety disorders
0.628 0.372 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.627 0.373 0.000
L40-L45 Papulosquamous disorders
0.627 0.373 0.000
H01 Other inflammation of eyelid
0.625 0.375 0.000
M54.8 Other dorsalgia
0.625 0.375 0.000
M54.6 Pain in thoracic spine
0.625 0.375 0.000
M54.0 Panniculitis affecting regions of neck and back
0.625 0.375 0.000
H25.9 Senile cataract, unspecified
0.625 0.375 0.000
M51 Other intervertebral disk disorders
0.624 0.376 0.000
F41.8 Other specified anxiety disorders
0.623 0.376 0.000
F41.3 Other mixed anxiety disorders
0.623 0.376 0.000
F41.1 Generalised anxiety disorder
0.623 0.376 0.000
S01 Open wound of head
0.622 0.378 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.622 0.378 0.000
M25.7 Osteophyte
0.621 0.379 0.000
M50.9 Cervical disk disorder, unspecified
0.621 0.379 0.000
M50.8 Other cervical disk disorders
0.621 0.379 0.000
H83 Other diseases of inner ear
0.620 0.380 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.618 0.381 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.618 0.382 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.618 0.382 0.000
F10.0 Acute intoxication
0.617 0.383 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.617 0.383 0.000
C51-C58 Malignant neoplasms of female genital organs
0.617 0.383 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.617 0.383 0.000
F41.2 Mixed anxiety and depressive disorder
0.616 0.384 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.614 0.386 0.000
H90 Conductive and sensorineural hearing loss
0.614 0.386 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.612 0.388 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.612 0.388 0.000
M42 Spinal osteochondrosis
0.611 0.389 0.000
M40 Kyphosis and lordosis
0.611 0.389 0.000
C50.5 Lower-outer quadrant of breast
0.611 0.389 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.611 0.389 0.000
H74 Other disorders of middle ear and mastoid
0.610 0.390 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.606 0.394 0.000
M45-M49 Spondylopathies
0.606 0.394 0.000
M22.4 Chondromalacia patellae
0.606 0.394 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.604 0.395 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.604 0.396 0.000
F20 Schizophrenia
0.604 0.396 0.000
S40-S49 Injuries to the shoulder and upper arm
0.602 0.398 0.000
C50.1 Central portion of breast
0.602 0.398 0.000
M77 Other enthesopathies
0.601 0.399 0.000
M76 Enthesopathies of lower limb, excluding foot
0.601 0.399 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.601 0.399 0.000
M71 Other bursopathies
0.601 0.399 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.601 0.399 0.000
H81 Disorders of vestibular function
0.600 0.400 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.600 0.400 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.598 0.402 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.598 0.402 0.000
M31.6 Other giant cell arteritis
0.597 0.403 0.000
H25.1 Senile nuclear cataract
0.596 0.404 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.594 0.405 0.000
M05.8 Other seropositive rheumatoid arthritis
0.593 0.407 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.593 0.407 0.000
M05.2 Rheumatoid vasculitis
0.593 0.407 0.000
M05.1 Rheumatoid lung disease
0.593 0.407 0.000
M05.0 Felty's syndrome
0.593 0.407 0.000
M50.3 Other cervical disk degeneration
0.591 0.409 0.000
M54.5 Low back pain
0.591 0.409 0.000
M50.2 Other cervical disk displacement
0.591 0.409 0.000
M24.1 Other articular cartilage disorders
0.591 0.409 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.590 0.410 0.000
M35.8 Other specified systemic involvement of connective tissue
0.590 0.410 0.000
M35.7 Hypermobility syndrome
0.590 0.410 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.590 0.410 0.000
M35.5 Multifocal fibrosclerosis
0.590 0.410 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.590 0.410 0.000
M35.2 Behcet's disease
0.590 0.410 0.000
M35.1 Other overlap syndromes
0.590 0.410 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.589 0.410 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.589 0.411 0.000
H91.9 Hearing loss, unspecified
0.589 0.411 0.000
S80-S89 Injuries to the knee and lower leg
0.589 0.411 0.000
G83 Other paralytic syndromes
0.587 0.413 0.000
M25.9 Joint disorder, unspecified
0.587 0.413 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.587 0.413 0.000
M25.3 Other instability of joint
0.587 0.413 0.000
M25.2 Flail joint
0.587 0.413 0.000
M25.1 Fistula of joint
0.587 0.413 0.000
M25.0 Haemarthrosis
0.587 0.413 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.586 0.414 0.000
M25.4 Effusion of joint
0.585 0.415 0.000
B35-B49 Mycoses
0.585 0.415 0.000
C78.2 Secondary malignant neoplasm of pleura
0.585 0.415 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.585 0.415 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.585 0.415 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.585 0.415 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.585 0.415 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.585 0.415 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.585 0.415 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.585 0.415 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.584 0.416 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.584 0.416 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.584 0.416 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.584 0.416 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.584 0.416 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.584 0.416 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.584 0.416 0.000
F11 Mental and behavioural disorders due to use of opioids
0.584 0.416 0.000
M13.94 Arthritis, unspecified (Hand)
0.584 0.416 0.000
H73 Other disorders of tympanic membrane
0.583 0.417 0.000
M43.1 Spondylolisthesis
0.582 0.418 0.000
D69.9 Haemorrhagic condition, unspecified
0.582 0.418 0.000
D69.8 Other specified haemorrhagic conditions
0.582 0.418 0.000
D69.5 Secondary thrombocytopenia
0.582 0.418 0.000
D69.4 Other primary thrombocytopenia
0.582 0.418 0.000
D69.2 Other nonthrombocytopenic purpura
0.582 0.418 0.000
D69.1 Qualitative platelet defects
0.582 0.418 0.000
D69.0 Allergic purpura
0.582 0.418 0.000
C91 Lymphoid leukaemia
0.582 0.418 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.582 0.418 0.000
G51 Facial nerve disorders
0.581 0.419 0.000
S20-S29 Injuries to the thorax
0.581 0.419 0.000
I27.8 Other specified pulmonary heart diseases
0.580 0.420 0.000
M22.1 Recurrent subluxation of patella
0.578 0.421 0.000
M22.9 Disorder of patella, unspecified
0.578 0.421 0.000
M22.3 Other derangements of patella
0.578 0.421 0.000
M22.2 Patellofemoral disorders
0.578 0.421 0.000
M22.0 Recurrent dislocation of patella
0.578 0.421 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.578 0.422 0.000
I86 Varicose veins of other sites
0.576 0.424 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.576 0.424 0.000
H05 Disorders of orbit
0.576 0.424 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.576 0.424 0.000
C09 Malignant neoplasm of tonsil
0.576 0.424 0.000
F03 Unspecified dementia
0.576 0.424 0.000
C50.6 Axillary tail of breast
0.575 0.424 0.000
C50.0 Nipple and areola
0.575 0.424 0.000
D06 Carcinoma in situ of cervix uteri
0.575 0.425 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.575 0.425 0.000
M54.22 Cervicalgia (Cervical region)
0.575 0.425 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.575 0.425 0.000
C79.6 Secondary malignant neoplasm of ovary
0.575 0.425 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.575 0.425 0.000
C79.2 Secondary malignant neoplasm of skin
0.575 0.425 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.575 0.425 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.575 0.425 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.575 0.425 0.000
H60 Otitis externa
0.575 0.425 0.000
G91.8 Other hydrocephalus
0.574 0.425 0.000
G91.3 Posttraumatic hydrocephalus, unspecified
0.574 0.425 0.000
G91.2 Normal-pressure hydrocephalus
0.574 0.425 0.000
G91.1 Obstructive hydrocephalus
0.574 0.425 0.000
G91.0 Communicating hydrocephalus
0.574 0.425 0.000
M41.9 Scoliosis, unspecified
0.574 0.425 0.000
B99-B99 Other infectious diseases
0.574 0.426 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.574 0.426 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.574 0.426 0.000
B65-B83 Helminthiases
0.574 0.426 0.000
B50-B64 Protozoal diseases
0.574 0.426 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.574 0.426 0.000
B15-B19 Viral hepatitis
0.574 0.426 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.574 0.426 0.000
A80-A89 Viral infections of the central nervous system
0.574 0.426 0.000
A75-A79 Rickettsioses
0.574 0.426 0.000
A70-A74 Other diseases caused by chlamydiae
0.574 0.426 0.000
A65-A69 Other spirochaetal diseases
0.574 0.426 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.574 0.426 0.000
A20-A28 Certain zoonotic bacterial diseases
0.574 0.426 0.000
A15-A19 Tuberculosis
0.574 0.426 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.573 0.427 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.573 0.427 0.000
H92 Otalgia and effusion of ear
0.573 0.427 0.000
H66 Suppurative and unspecified otitis media
0.573 0.427 0.000
H51 Other disorders of binocular movement
0.572 0.428 0.000
H49 Paralytic strabismus
0.572 0.428 0.000
I00-I02 Acute rheumatic fever
0.571 0.428 0.000
I84 Haemorrhoids
0.571 0.429 0.000
G93.9 Disorder of brain, unspecified
0.571 0.429 0.000
G93.8 Other specified disorders of brain
0.571 0.429 0.000
G93.7 Reye's syndrome
0.571 0.429 0.000
G93.6 Cerebral oedema
0.571 0.429 0.000
G93.5 Compression of brain
0.571 0.429 0.000
G93.4 Encephalopathy, unspecified
0.571 0.429 0.000
G93.2 Benign intracranial hypertension
0.571 0.429 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.571 0.429 0.000
T79-T79 Certain early complications of trauma
0.570 0.430 0.000
C92 Myeloid leukaemia
0.570 0.430 0.000
M93 Other osteochondropathies
0.570 0.430 0.000
M92 Other juvenile osteochondrosis
0.570 0.430 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.570 0.430 0.000
H61.0 Perichondritis of external ear
0.569 0.431 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.567 0.432 0.000
M23.9 Internal derangement of knee, unspecified
0.567 0.432 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.567 0.432 0.000
M23.5 Chronic instability of knee
0.567 0.432 0.000
M23.1 Discoid meniscus (congenital)
0.567 0.432 0.000
M23.0 Cystic meniscus
0.567 0.432 0.000
M10.9 Gout, unspecified
0.567 0.433 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.565 0.435 0.000
G40 Epilepsy
0.563 0.437 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.563 0.437 0.000
H43 Disorders of vitreous body
0.563 0.437 0.000
A30-A49 Other bacterial diseases
0.562 0.438 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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