TreeWAS – Variant ID: rs73976923

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
E11.9 Without complications	0.064	0.936
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.062	0.938
# Top node	0.062	0.938
E11 Non-insulin-dependent diabetes mellitus	0.060	0.940
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.059	0.941
M20-M25 Other joint disorders	0.058	0.942
E10-E14 Diabetes mellitus	0.057	0.943
Chapter IV Endocrine, nutritional and metabolic diseases	0.057	0.943
Chapter I Certain infectious and parasitic diseases	0.056	0.944
Chapter XV Pregnancy, childbirth and the puerperium	0.055	0.945
M15-M19 Arthrosis	0.055	0.945
M23 Internal derangement of knee	0.054	0.946
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.054	0.946
Chapter V Mental and behavioural disorders	0.054	0.946
M65-M68 Disorders of synovium and tendon	0.052	0.948
Chapter II Neoplasms	0.052	0.948
M17 Gonarthrosis [arthrosis of knee]	0.052	0.948
S60-S69 Injuries to the wrist and hand	0.051	0.949
Chapter XI Diseases of the digestive system	0.050	0.950
M23.2 Derangement of meniscus due to old tear or injury	0.050	0.950
O60-O75 Complications of labour and delivery	0.049	0.951
T85 Complications of other internal prosthetic devices, implants and grafts	0.048	0.952
Chapter XX External causes of morbidity and mortality	0.048	0.952
B25-B34 Other viral diseases	0.047	0.953
Chapter VI Diseases of the nervous system	0.047	0.953
M17.9 Gonarthrosis, unspecified	0.047	0.953
M70-M79 Other soft tissue disorders	0.047	0.953
S61 Open wound of wrist and hand	0.046	0.954
M45-M49 Spondylopathies	0.046	0.954
M25 Other joint disorders, not elsewhere classified	0.046	0.954
M23.3 Other meniscus derangements	0.046	0.954
Chapter VII Diseases of the eye and adnexa	0.045	0.955
F40-F48 Neurotic, stress-related and somatoform disorders	0.045	0.955
O70 Perineal laceration during delivery	0.045	0.955
A00-A09 Intestinal infectious diseases	0.045	0.955
M17.1 Other primary gonarthrosis	0.045	0.955
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.045	0.955
M91-M94 Chondropathies	0.045	0.955
M86-M90 Other osteopathies	0.045	0.955
M60-M63 Disorders of muscles	0.045	0.955
M40-M43 Deforming dorsopathies	0.045	0.955
M00-M03 Infectious arthropathies	0.045	0.955
Chapter XXII Codes for special purposes	0.044	0.956
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.044	0.956
Chapter XVI Certain conditions originating in the perinatal period	0.044	0.956
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.044	0.956
M05-M14 Inflammatory polyarthropathies	0.044	0.956
F30-F39 Mood [affective] disorders	0.044	0.956
E00-E07 Disorders of thyroid gland	0.044	0.956
B95-B98 Bacterial, viral and other infectious agents	0.044	0.956
M50-M54 Other dorsopathies	0.043	0.956
E11.8 With unspecified complications	0.043	0.957
E11.7 With multiple complications	0.043	0.957
E11.6 With other specified complications	0.043	0.957
E11.5 With peripheral circulatory complications	0.043	0.957
E11.4 With neurological complications	0.043	0.957
E11.3 With ophthalmic complications	0.043	0.957
E11.2 With renal complications	0.043	0.957
E11.1 With ketoacidosis	0.043	0.957
E11.0 With coma	0.043	0.957
Chapter VIII Diseases of the ear and mastoid process	0.043	0.957
T81 Complications of procedures, not elsewhere classified	0.043	0.957
M65 Synovitis and tenosynovitis	0.043	0.957
M80-M85 Disorders of bone density and structure	0.043	0.957
S61.0 Open wound of finger(s) without damage to nail	0.043	0.957
O70.1 Second degree perineal laceration during delivery	0.042	0.958
B35-B49 Mycoses	0.042	0.958
O80-O84 Delivery	0.042	0.958
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.042	0.958
T79-T79 Certain early complications of trauma	0.042	0.958
T66-T78 Other and unspecified effects of external causes	0.042	0.958
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.042	0.958
T36-T50 Poisoning by drugs, medicaments and biological substances	0.042	0.958
T33-T35 Frostbite	0.042	0.958
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.042	0.958
T26-T28 Burns and corrosions confined to eye and internal organs	0.042	0.958
T20-T25 Burns and corrosions of external body surface, specified by site	0.042	0.958
T15-T19 Effects of foreign body entering through natural orifice	0.042	0.958
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.042	0.958
T00-T07 Injuries involving multiple body regions	0.042	0.958
S90-S99 Injuries to the ankle and foot	0.042	0.958
S70-S79 Injuries to the hip and thigh	0.042	0.958
S40-S49 Injuries to the shoulder and upper arm	0.042	0.958
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.042	0.958
S20-S29 Injuries to the thorax	0.042	0.958
S10-S19 Injuries to the neck	0.042	0.958
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.042	0.958
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.042	0.958
M67 Other disorders of synovium and tendon	0.042	0.958
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.042	0.958
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.042	0.958
M35 Other systemic involvement of connective tissue	0.042	0.958
M34 Systemic sclerosis	0.042	0.958
M33 Dermatopolymyositis	0.042	0.958
M32 Systemic lupus erythematosus	0.042	0.958
M31 Other necrotising vasculopathies	0.042	0.958
M30 Polyarteritis nodosa and related conditions	0.042	0.958
M24 Other specific joint derangements	0.042	0.958
M22 Disorders of patella	0.042	0.958
M21 Other acquired deformities of limbs	0.042	0.958
S00-S09 Injuries to the head	0.041	0.958
E13 Other specified diabetes mellitus	0.041	0.959
E12 Malnutrition-related diabetes mellitus	0.041	0.959
S50-S59 Injuries to the elbow and forearm	0.041	0.959
E50-E64 Other nutritional deficiencies	0.041	0.959
E40-E46 Malnutrition	0.041	0.959
E20-E35 Disorders of other endocrine glands	0.041	0.959
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.041	0.959
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.041	0.959
S80-S89 Injuries to the knee and lower leg	0.041	0.959
C60-C63 Malignant neoplasms of male genital organs	0.041	0.959
B34 Viral infection of unspecified site	0.041	0.959
O20-O29 Other maternal disorders predominantly related to pregnancy	0.041	0.959
T85.4 Mechanical complication of breast prosthesis and implant	0.040	0.959
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.040	0.959
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.040	0.960
B99-B99 Other infectious diseases	0.040	0.960
B90-B94 Sequelae of infectious and parasitic diseases	0.040	0.960
B85-B89 Pediculosis, acariasis and other infestations	0.040	0.960
B65-B83 Helminthiases	0.040	0.960
B50-B64 Protozoal diseases	0.040	0.960
B20-B24 Human immunodeficiency virus [HIV] disease	0.040	0.960
B15-B19 Viral hepatitis	0.040	0.960
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.040	0.960
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.040	0.960
A80-A89 Viral infections of the central nervous system	0.040	0.960
A75-A79 Rickettsioses	0.040	0.960
A70-A74 Other diseases caused by chlamydiae	0.040	0.960
A65-A69 Other spirochaetal diseases	0.040	0.960
A50-A64 Infections with a predominantly sexual mode of transmission	0.040	0.960
A20-A28 Certain zoonotic bacterial diseases	0.040	0.960
A15-A19 Tuberculosis	0.040	0.960
A30-A49 Other bacterial diseases	0.040	0.960
D10-D36 Benign neoplasms	0.040	0.960
O94-O99 Other obstetric conditions, not elsewhere classified	0.040	0.960
O85-O92 Complications predominantly related to the puerperium	0.040	0.960
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.040	0.960
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.040	0.960
O00-O08 Pregnancy with abortive outcome	0.040	0.960
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.040	0.960
M18 Arthrosis of first carpometacarpal joint	0.039	0.961
M15 Polyarthrosis	0.039	0.961
Chapter X Diseases of the respiratory system	0.039	0.961
M23.9 Internal derangement of knee, unspecified	0.039	0.961
M23.8 Other internal derangements of knee	0.039	0.961
M23.6 Other spontaneous disruption of ligament(s) of knee	0.039	0.961
M23.5 Chronic instability of knee	0.039	0.961
M23.4 Loose body in knee	0.039	0.961
M23.1 Discoid meniscus (congenital)	0.039	0.961
M23.0 Cystic meniscus	0.039	0.961
E14 Unspecified diabetes mellitus	0.039	0.961
M20 Acquired deformities of fingers and toes	0.039	0.961
Chapter XII Diseases of the skin and subcutaneous tissue	0.039	0.961
K65-K67 Diseases of peritoneum	0.039	0.961
T88 Other complications of surgical and medical care, not elsewhere classified	0.039	0.961
T87 Complications peculiar to reattachment and amputation	0.039	0.961
T86 Failure and rejection of transplanted organs and tissues	0.039	0.961
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.039	0.961
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.039	0.961
T80 Complications following infusion, transfusion and therapeutic injection	0.039	0.961
F99-F99 Unspecified mental disorder	0.039	0.961
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.039	0.961
F80-F89 Disorders of psychological development	0.039	0.961
F70-F79 Mental retardation	0.039	0.961
F60-F69 Disorders of adult personality and behaviour	0.039	0.961
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.039	0.961
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.039	0.961
F00-F09 Organic, including symptomatic, mental disorders	0.039	0.961
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.039	0.961
K90-K93 Other diseases of the digestive system	0.038	0.962
T81.4 Infection following a procedure, not elsewhere classified	0.038	0.962
C79 Secondary malignant neoplasm of other sites	0.038	0.962
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.038	0.962
M66 Spontaneous rupture of synovium and tendon	0.038	0.962
D37-D48 Neoplasms of uncertain or unknown behaviour	0.038	0.962
D00-D09 In situ neoplasms	0.038	0.962
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.038	0.962
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.038	0.962
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.038	0.962
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.038	0.962
C51-C58 Malignant neoplasms of female genital organs	0.038	0.962
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.038	0.962
C40-C41 Malignant neoplasms of bone and articular cartilage	0.038	0.962
C15-C26 Malignant neoplasms of digestive organs	0.038	0.962
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.038	0.962
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.038	0.962
F40 Phobic anxiety disorders	0.037	0.962
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.037	0.962
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.037	0.963
M17.5 Other secondary gonarthrosis	0.037	0.963
M17.4 Other secondary gonarthrosis, bilateral	0.037	0.963
M17.3 Other posttraumatic gonarthrosis	0.037	0.963
M17.2 Posttraumatic gonarthrosis, bilateral	0.037	0.963
M17.0 Primary gonarthrosis, bilateral	0.037	0.963
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.037	0.963
S69 Other and unspecified injuries of wrist and hand	0.037	0.963
S68 Traumatic amputation of wrist and hand	0.037	0.963
S67 Crushing injury of wrist and hand	0.037	0.963
S66 Injury of muscle and tendon at wrist and hand level	0.037	0.963
S65 Injury of blood vessels at wrist and hand level	0.037	0.963
S64 Injury of nerves at wrist and hand level	0.037	0.963
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.037	0.963
S62 Fracture at wrist and hand level	0.037	0.963
S60 Superficial injury of wrist and hand	0.037	0.963
F32 Depressive episode	0.037	0.963
K20-K31 Diseases of oesophagus, stomach and duodenum	0.037	0.963
E10 Insulin-dependent diabetes mellitus	0.036	0.963
K35-K38 Diseases of appendix	0.036	0.963
C64-C68 Malignant neoplasms of urinary tract	0.036	0.963
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.036	0.963
B34.9 Viral infection, unspecified	0.036	0.964
M25.7 Osteophyte	0.036	0.964
M75 Shoulder lesions	0.036	0.964
K70-K77 Diseases of liver	0.036	0.964
M16 Coxarthrosis [arthrosis of hip]	0.036	0.964
W00-W19 Falls	0.036	0.964
C43-C44 Melanoma and other malignant neoplasms of skin	0.036	0.964
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.036	0.964
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.036	0.964
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.036	0.964
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.036	0.964
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.036	0.964
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.036	0.964
F41 Other anxiety disorders	0.036	0.964
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.036	0.964
O75 Other complications of labour and delivery, not elsewhere classified	0.035	0.964
O74 Complications of anaesthesia during labour and delivery	0.035	0.964
O73 Retained placenta and membranes, without haemorrhage	0.035	0.964
O72 Postpartum haemorrhage	0.035	0.964
O71 Other obstetric trauma	0.035	0.964
O69 Labour and delivery complicated by umbilical cord complications	0.035	0.964
O68 Labour and delivery complicated by foetal stress [distress]	0.035	0.964
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.035	0.964
O66 Other obstructed labour	0.035	0.964
O65 Obstructed labour due to maternal pelvic abnormality	0.035	0.964
O64 Obstructed labour due to malposition and malpresentation of foetus	0.035	0.964
O63 Long labour	0.035	0.964
O62 Abnormalities of forces of labour	0.035	0.964
O61 Failed induction of labour	0.035	0.964
O60 Preterm delivery	0.035	0.964
G40-G47 Episodic and paroxysmal disorders	0.035	0.965
M65.9 Synovitis and tenosynovitis, unspecified	0.035	0.965
K40-K46 Hernia	0.035	0.965
M19 Other arthrosis	0.035	0.965
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.035	0.965
K80 Cholelithiasis	0.035	0.965
H53-H54 Visual disturbances and blindness	0.035	0.965
E65-E68 Obesity and other hyperalimentation	0.034	0.965
M25.5 Pain in joint	0.035	0.965
M47 Spondylosis	0.035	0.965
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.035	0.965
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.035	0.965
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.035	0.965
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.035	0.965
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.035	0.965
T85.2 Mechanical complication of intraocular lens	0.035	0.965
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.035	0.965
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.035	0.965
G50-G59 Nerve, nerve root and plexus disorders	0.034	0.965
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.034	0.965
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.034	0.965
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.034	0.965
Y60-Y69 Misadventures to patients during surgical and medical care	0.034	0.965
Y35-Y36 Legal intervention and operations of war	0.034	0.965
Y10-Y34 Event of undetermined intent	0.034	0.965
Y00-Y09 Assault	0.034	0.965
X85-X99 Assault	0.034	0.965
X60-X84 Intentional self-harm	0.034	0.965
X58-X59 Accidental exposure to other and unspecified factors	0.034	0.965
X50-X57 Overexertion, travel and privation	0.034	0.965
X40-X49 Accidental poisoning by and exposure to noxious substances	0.034	0.965
X30-X39 Exposure to forces of nature	0.034	0.965
X20-X29 Contact with venomous animals and plants	0.034	0.965
X10-X19 Contact with heat and hot substances	0.034	0.965
X00-X09 Exposure to smoke, fire and flames	0.034	0.965
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.034	0.965
W75-W84 Other accidental threats to breathing	0.034	0.965
W65-W74 Accidental drowning and submersion	0.034	0.965
W50-W64 Exposure to animate mechanical forces	0.034	0.965
W20-W49 Exposure to inanimate mechanical forces	0.034	0.965
V98-V99 Other and unspecified transport accidents	0.034	0.965
V95-V97 Air and space transport accidents	0.034	0.965
V90-V94 Water transport accidents	0.034	0.965
V80-V89 Other land transport accidents	0.034	0.965
V70-V79 Bus occupant injured in transport accident	0.034	0.965
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.034	0.965
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.034	0.965
V40-V49 Car occupant injured in transport accident	0.034	0.965
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.034	0.965
V20-V29 Motorcycle rider injured in transport accident	0.034	0.965
V10-V19 Pedal cyclist injured in transport accident	0.034	0.965
V01-V09 Pedestrian injured in transport accident	0.034	0.965
E03 Other hypothyroidism	0.034	0.966
G80-G83 Cerebral palsy and other paralytic syndromes	0.034	0.966
K55-K64 Other diseases of intestines	0.034	0.966
M67.8 Other specified disorders of synovium and tendon	0.034	0.966
B33 Other viral diseases, not elsewhere classified	0.034	0.966
B30 Viral conjunctivitis	0.034	0.966
B27 Infectious mononucleosis	0.034	0.966
B26 Mumps	0.034	0.966
B25 Cytomegaloviral disease	0.034	0.966
G90-G99 Other disorders of the nervous system	0.034	0.966
G70-G73 Diseases of myoneural junction and muscle	0.034	0.966
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.034	0.966
G35-G37 Demyelinating diseases of the central nervous system	0.034	0.966
G30-G32 Other degenerative diseases of the nervous system	0.034	0.966
G20-G26 Extrapyramidal and movement disorders	0.034	0.966
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.034	0.966
G00-G09 Inflammatory diseases of the central nervous system	0.034	0.966
K22 Other diseases of oesophagus	0.034	0.966
T81.3 Disruption of operation wound, not elsewhere classified	0.034	0.966
M77 Other enthesopathies	0.033	0.966
M76 Enthesopathies of lower limb, excluding foot	0.033	0.966
M73 Soft tissue disorders in diseases classified elsewhere	0.033	0.966
M71 Other bursopathies	0.033	0.966
M70 Soft tissue disorders related to use, overuse and pressure	0.033	0.966
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.034	0.966
D23 Other benign neoplasms of skin	0.033	0.966
O70.0 First degree perineal laceration during delivery	0.033	0.967
S61.9 Open wound of wrist and hand, part unspecified	0.033	0.967
S61.8 Open wound of other parts of wrist and hand	0.033	0.967
S61.7 Multiple open wounds of wrist and hand	0.033	0.967
S61.1 Open wound of finger(s) with damage to nail	0.033	0.967
M49 Spondylopathies in diseases classified elsewhere	0.033	0.967
M48 Other spondylopathies	0.033	0.967
M46 Other inflammatory spondylopathies	0.033	0.967
M45 Ankylosing spondylitis	0.033	0.967
M79 Other soft tissue disorders, not elsewhere classified	0.033	0.967
C34 Malignant neoplasm of bronchus and lung	0.033	0.967
M25.9 Joint disorder, unspecified	0.033	0.967
M25.8 Other specified joint disorders	0.033	0.967
M25.6 Stiffness of joint, not elsewhere classified	0.033	0.967
M25.4 Effusion of joint	0.033	0.967
M25.3 Other instability of joint	0.033	0.967
M25.2 Flail joint	0.033	0.967
M25.1 Fistula of joint	0.033	0.967
M25.0 Haemarthrosis	0.033	0.967
O80 Single spontaneous delivery	0.033	0.967
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.033	0.967
Chapter XIV Diseases of the genitourinary system	0.033	0.967
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.033	0.967
M23.37 Other meniscus derangements-Capsular lig	0.033	0.967
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.033	0.967
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.033	0.967
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.033	0.967
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.033	0.967
M23.30 Other meniscus derangements (Multiple sites)	0.033	0.967
M72 Fibroblastic disorders	0.033	0.967
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.033	0.967
H55-H59 Other disorders of eye and adnexa	0.033	0.967
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.033	0.967
H46-H48 Disorders of optic nerve and visual pathways	0.033	0.967
H43-H45 Disorders of vitreous body and globe	0.033	0.967
H40-H42 Glaucoma	0.033	0.967
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.033	0.967
H10-H13 Disorders of conjunctiva	0.033	0.967
F48 Other neurotic disorders	0.033	0.967
F45 Somatoform disorders	0.033	0.967
F44 Dissociative [conversion] disorders	0.033	0.967
F43 Reaction to severe stress, and adjustment disorders	0.033	0.967
F42 Obsessive-compulsive disorder	0.033	0.967
O70.9 Perineal laceration during delivery, unspecified	0.033	0.967
O70.3 Fourth degree perineal laceration during delivery	0.033	0.967
O70.2 Third degree perineal laceration during delivery	0.033	0.967
B37 Candidiasis	0.033	0.967
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.032	0.967
M54 Dorsalgia	0.033	0.967
A08 Viral and other specified intestinal infections	0.032	0.967
A07 Other protozoal intestinal diseases	0.032	0.967
A06 Amoebiasis	0.032	0.967
A05 Other bacterial foodborne intoxications	0.032	0.967
A04 Other bacterial intestinal infections	0.032	0.967
A03 Shigellosis	0.032	0.967
A02 Other Salmonella infections	0.032	0.967
A01 Typhoid and paratyphoid fevers	0.032	0.967
A00 Cholera	0.032	0.967
C61 Malignant neoplasm of prostate	0.033	0.967
K50-K52 Noninfective enteritis and colitis	0.032	0.967
D17 Benign lipomatous neoplasm	0.032	0.968
M65.3 Trigger finger	0.032	0.968
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.032	0.968
M02 Reactive arthropathies	0.032	0.968
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.032	0.968
M00 Pyogenic arthritis	0.032	0.968
M43 Other deforming dorsopathies	0.032	0.968
M42 Spinal osteochondrosis	0.032	0.968
M41 Scoliosis	0.032	0.968
M40 Kyphosis and lordosis	0.032	0.968
M63 Disorders of muscle in diseases classified elsewhere	0.032	0.968
M62 Other disorders of muscle	0.032	0.968
M61 Calcification and ossification of muscle	0.032	0.968
M60 Myositis	0.032	0.968
M90 Osteopathies in diseases classified elsewhere	0.032	0.968
M89 Other disorders of bone	0.032	0.968
M88 Paget's disease of bone [osteitis deformans]	0.032	0.968
M87 Osteonecrosis	0.032	0.968
M86 Osteomyelitis	0.032	0.968
M94 Other disorders of cartilage	0.032	0.968
M93 Other osteochondropathies	0.032	0.968
M92 Other juvenile osteochondrosis	0.032	0.968
M91 Juvenile osteochondrosis of hip and pelvis	0.032	0.968
M99 Biomechanical lesions, not elsewhere classified	0.032	0.968
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.032	0.968
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.032	0.968
K83 Other diseases of biliary tract	0.032	0.968
P90-P96 Other disorders originating in the perinatal period	0.032	0.968
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.032	0.968
P75-P78 Digestive system disorders of fetus and newborn	0.032	0.968
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.032	0.968
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.032	0.968
P35-P39 Infections specific to the perinatal period	0.032	0.968
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.032	0.968
P10-P15 Birth trauma	0.032	0.968
P05-P08 Disorders related to length of gestation and fetal growth	0.032	0.968
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.032	0.968
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.032	0.968
Q80-Q89 Other congenital malformations	0.032	0.968
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.032	0.968
Q60-Q64 Congenital malformations of the urinary system	0.032	0.968
Q50-Q56 Congenital malformations of genital organs	0.032	0.968
Q38-Q45 Other congenital malformations of the digestive system	0.032	0.968
Q35-Q37 Cleft lip and cleft palate	0.032	0.968
Q30-Q34 Congenital malformations of the respiratory system	0.032	0.968
Q20-Q28 Congenital malformations of the circulatory system	0.032	0.968
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.032	0.968
Q00-Q07 Congenital malformations of the nervous system	0.032	0.968
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.032	0.968
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.032	0.968
F32.9 Depressive episode, unspecified	0.032	0.968
J30-J39 Other diseases of upper respiratory tract	0.032	0.968
A09.9 Gastroenteritis and colitis of unspecified origin	0.032	0.968
C80 Malignant neoplasm without specification of site	0.032	0.968
C76 Malignant neoplasm of other and ill-defined sites	0.032	0.968
C50-C50 Malignant neoplasm of breast	0.032	0.968
F40.2 Specific (isolated) phobias	0.032	0.968
M14 Arthropathies in other diseases classified elsewhere	0.032	0.968
M12 Other specific arthropathies	0.032	0.968
M11 Other crystal arthropathies	0.032	0.968
M10 Gout	0.032	0.968
M09 Juvenile arthritis in diseases classified elsewhere	0.032	0.968
M08 Juvenile arthritis	0.032	0.968
M07 Psoriatic and enteropathic arthropathies	0.032	0.968
M05 Seropositive rheumatoid arthritis	0.032	0.968
F38 Other mood [affective] disorders	0.032	0.968
F34 Persistent mood [affective] disorders	0.032	0.968
F33 Recurrent depressive disorder	0.032	0.968
F31 Bipolar affective disorder	0.032	0.968
F30 Manic episode	0.032	0.968
F39 Unspecified mood [affective] disorder	0.032	0.968
D27 Benign neoplasm of ovary	0.032	0.968
E07 Other disorders of thyroid	0.031	0.968
E06 Thyroiditis	0.031	0.968
E05 Thyrotoxicosis [hyperthyroidism]	0.031	0.968
E04 Other non-toxic goitre	0.031	0.968
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.031	0.968
E00 Congenital iodine-deficiency syndrome	0.031	0.968
E02 Subclinical iodine-deficiency hypothyroidism	0.031	0.968
M06 Other rheumatoid arthritis	0.031	0.968
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.031	0.968
B97 Viral agents as the cause of diseases classified to other chapters	0.031	0.968
M53 Other dorsopathies, not elsewhere classified	0.031	0.969
M50 Cervical disk disorders	0.031	0.969
M13 Other arthritis	0.031	0.969
H80-H83 Diseases of inner ear	0.031	0.969
H65-H75 Diseases of middle ear and mastoid	0.031	0.969
H60-H62 Diseases of external ear	0.031	0.969
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.031	0.969
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.031	0.969
H30-H36 Disorders of choroid and retina	0.031	0.969
T81.9 Unspecified complication of procedure	0.031	0.969
T81.8 Other complications of procedures, not elsewhere classified	0.031	0.969
T81.7 Vascular complications following a procedure, not elsewhere classified	0.031	0.969
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.031	0.969
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.031	0.969
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.031	0.969
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.031	0.969
M65.8 Other synovitis and tenosynovitis	0.031	0.969
M65.4 Radial styloid tenosynovitis [de Quervain]	0.031	0.969
M65.2 Calcific tendinitis	0.031	0.969
M65.1 Other infective (teno)synovitis	0.031	0.969
M65.0 Abscess of tendon sheath	0.031	0.969
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.031	0.969
M85 Other disorders of bone density and structure	0.031	0.969
M84 Disorders of continuity of bone	0.031	0.969
M83 Adult osteomalacia	0.031	0.969
M82 Osteoporosis in diseases classified elsewhere	0.031	0.969
M80 Osteoporosis with pathological fracture	0.031	0.969
G45 Transient cerebral ischaemic attacks and related syndromes	0.031	0.969
K66 Other disorders of peritoneum	0.031	0.969
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.031	0.969
B48 Other mycoses, not elsewhere classified	0.030	0.969
B47 Mycetoma	0.030	0.969
B46 Zygomycosis	0.030	0.969
B45 Cryptococcosis	0.030	0.969
B44 Aspergillosis	0.030	0.969
B43 Chromomycosis and phaeomycotic abscess	0.030	0.969
B42 Sporotrichosis	0.030	0.969
B41 Paracoccidioidomycosis	0.030	0.969
B40 Blastomycosis	0.030	0.969
B39 Histoplasmosis	0.030	0.969

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations