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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74156047
log Bayes Factor = 30.5215
Chromosome 1   position 210,892,311  (GRCh37) Explore rs74156047 on Ensembl!
Variant rs74156047 is part of Cluster X0152

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.998 0.002 0.000
R07 Pain in throat and chest
0.997 0.003 0.000
C34 Malignant neoplasm of bronchus and lung
0.997 0.003 0.000
R50-R69 General symptoms and signs
0.996 0.004 0.000
N17 Acute renal failure
0.996 0.004 0.000
M15-M19 Arthrosis
0.996 0.004 0.000
I30-I52 Other forms of heart disease
0.995 0.005 0.000
Chapter VI Diseases of the nervous system
0.995 0.005 0.000
N17.9 Acute renal failure, unspecified
0.994 0.006 0.000
R00 Abnormalities of heart beat
0.993 0.007 0.000
C34.9 Bronchus or lung, unspecified
0.991 0.009 0.000
R07.4 Chest pain, unspecified
0.991 0.009 0.000
M19 Other arthrosis
0.991 0.009 0.000
Chapter V Mental and behavioural disorders
0.990 0.010 0.000
M19.9 Arthrosis, unspecified
0.986 0.014 0.000
M75 Shoulder lesions
0.986 0.014 0.000
I60-I69 Cerebrovascular diseases
0.986 0.014 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.980 0.020 0.000
N18 Chronic renal failure
0.980 0.020 0.000
R06 Abnormalities of breathing
0.980 0.020 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.979 0.021 0.000
Chapter X Diseases of the respiratory system
0.979 0.021 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.975 0.025 0.000
S60-S69 Injuries to the wrist and hand
0.974 0.026 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.974 0.026 0.000
N30-N39 Other diseases of urinary system
0.973 0.027 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.966 0.034 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.966 0.034 0.000
G40-G47 Episodic and paroxysmal disorders
0.961 0.039 0.000
R55 Syncope and collapse
0.953 0.047 0.000
N39 Other disorders of urinary system
0.952 0.048 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.951 0.049 0.000
S00-S09 Injuries to the head
0.950 0.050 0.000
Chapter XX External causes of morbidity and mortality
0.948 0.052 0.000
R06.0 Dyspnoea
0.946 0.054 0.000
R00.0 Tachycardia, unspecified
0.943 0.057 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.942 0.058 0.000
E70-E90 Metabolic disorders
0.940 0.060 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.939 0.061 0.000
M75.4 Impingement syndrome of shoulder
0.938 0.062 0.000
R52 Pain, not elsewhere classified
0.938 0.062 0.000
M79.8 Other specified soft tissue disorders
0.935 0.065 0.000
Chapter I Certain infectious and parasitic diseases
0.934 0.066 0.000
R07.2 Precordial pain
0.932 0.068 0.000
R00.2 Palpitations
0.931 0.069 0.000
S09 Other and unspecified injuries of head
0.926 0.074 0.000
M05-M14 Inflammatory polyarthropathies
0.925 0.075 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.924 0.076 0.000
R56 Convulsions, not elsewhere classified
0.924 0.076 0.000
R42 Dizziness and giddiness
0.920 0.080 0.000
I44 Atrioventricular and left bundle-branch block
0.919 0.081 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.918 0.082 0.000
I51 Complications and ill-defined descriptions of heart disease
0.917 0.083 0.000
G47 Sleep disorders
0.915 0.085 0.000
M79.6 Pain in limb
0.915 0.085 0.000
F10.2 Dependence syndrome
0.912 0.088 0.000
M45-M49 Spondylopathies
0.909 0.091 0.000
S09.9 Unspecified injury of head
0.909 0.091 0.000
N18.9 Chronic renal failure, unspecified
0.907 0.093 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.906 0.094 0.000
N39.3 Stress incontinence
0.900 0.100 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.899 0.101 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.898 0.102 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.894 0.106 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.893 0.107 0.000
E83 Disorders of mineral metabolism
0.880 0.120 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.879 0.121 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.878 0.122 0.000
N81 Female genital prolapse
0.877 0.123 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.877 0.123 0.000
I35 Nonrheumatic aortic valve disorders
0.877 0.123 0.000
Chapter VII Diseases of the eye and adnexa
0.877 0.123 0.000
G90-G99 Other disorders of the nervous system
0.876 0.124 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.874 0.126 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.873 0.127 0.000
R56.8 Other and unspecified convulsions
0.873 0.127 0.000
M75.1 Rotator cuff syndrome
0.872 0.128 0.000
I60 Subarachnoid haemorrhage
0.870 0.130 0.000
Chapter XI Diseases of the digestive system
0.870 0.130 0.000
R60 Oedema, not elsewhere classified
0.869 0.131 0.000
C34.1 Upper lobe, bronchus or lung
0.867 0.133 0.000
I63 Cerebral infarction
0.866 0.134 0.000
B35-B49 Mycoses
0.865 0.135 0.000
N81.6 Rectocele
0.864 0.136 0.000
N18.4 Chronic kidney disease, stage 4
0.860 0.140 0.000
J20-J22 Other acute lower respiratory infections
0.859 0.141 0.000
R00.1 Bradycardia, unspecified
0.859 0.141 0.000
E86 Volume depletion
0.857 0.143 0.000
J09-J18 Influenza and pneumonia
0.857 0.143 0.000
I38 Endocarditis, valve unspecified
0.856 0.144 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.856 0.144 0.000
C64-C68 Malignant neoplasms of urinary tract
0.856 0.144 0.000
W00-W19 Falls
0.854 0.146 0.000
I49 Other cardiac arrhythmias
0.853 0.147 0.000
N20-N23 Urolithiasis
0.851 0.149 0.000
N39.0 Urinary tract infection, site not specified
0.851 0.149 0.000
C51-C58 Malignant neoplasms of female genital organs
0.851 0.149 0.000
E83.4 Disorders of magnesium metabolism
0.850 0.150 0.000
I44.7 Left bundle-branch block, unspecified
0.850 0.150 0.000
M47 Spondylosis
0.849 0.150 0.000
I42 Cardiomyopathy
0.849 0.151 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.848 0.152 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.844 0.156 0.000
S64 Injury of nerves at wrist and hand level
0.843 0.157 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.840 0.159 0.000
C34.0 Main bronchus
0.840 0.160 0.000
N00-N08 Glomerular diseases
0.840 0.160 0.000
F17.1 Harmful use
0.839 0.161 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.836 0.164 0.000
C34.3 Lower lobe, bronchus or lung
0.835 0.165 0.000
G47.3 Sleep apnoea
0.834 0.166 0.000
M77 Other enthesopathies
0.832 0.168 0.000
M16 Coxarthrosis [arthrosis of hip]
0.832 0.168 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.830 0.170 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.830 0.170 0.000
K40-K46 Hernia
0.830 0.170 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.828 0.172 0.000
N99-N99 Other disorders of the genitourinary system
0.828 0.172 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.828 0.172 0.000
S61 Open wound of wrist and hand
0.823 0.177 0.000
N18.3 Chronic kidney disease, stage 3
0.822 0.178 0.000
M50-M54 Other dorsopathies
0.822 0.178 0.000
R06.5 Mouth breathing
0.821 0.179 0.000
J95-J99 Other diseases of the respiratory system
0.820 0.180 0.000
G56 Mononeuropathies of upper limb
0.820 0.180 0.000
K35-K38 Diseases of appendix
0.819 0.181 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.819 0.181 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.817 0.183 0.000
M18 Arthrosis of first carpometacarpal joint
0.817 0.183 0.000
E20-E35 Disorders of other endocrine glands
0.816 0.184 0.000
S80-S89 Injuries to the knee and lower leg
0.814 0.186 0.000
N19 Unspecified renal failure
0.813 0.187 0.000
D68 Other coagulation defects
0.813 0.187 0.000
R59 Enlarged lymph nodes
0.812 0.187 0.000
G47.9 Sleep disorder, unspecified
0.810 0.190 0.000
A30-A49 Other bacterial diseases
0.809 0.191 0.000
M75.2 Bicipital tendinitis
0.808 0.192 0.000
C60-C63 Malignant neoplasms of male genital organs
0.807 0.193 0.000
T79-T79 Certain early complications of trauma
0.806 0.194 0.000
I69 Sequelae of cerebrovascular disease
0.806 0.194 0.000
M05 Seropositive rheumatoid arthritis
0.805 0.195 0.000
C85.1 B-cell lymphoma, unspecified
0.805 0.195 0.000
R60.0 Localised oedema
0.804 0.196 0.000
R52.1 Chronic intractable pain
0.804 0.196 0.000
J40-J47 Chronic lower respiratory diseases
0.803 0.197 0.000
I61 Intracerebral haemorrhage
0.802 0.198 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.802 0.198 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.801 0.199 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.800 0.200 0.000
I44.6 Other and unspecified fascicular block
0.798 0.202 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.798 0.202 0.000
M19.0 Primary arthrosis of other joints
0.797 0.203 0.000
K35 Acute appendicitis
0.796 0.204 0.000
N20 Calculus of kidney and ureter
0.796 0.204 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.796 0.204 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.795 0.205 0.000
M16.1 Other primary coxarthrosis
0.794 0.206 0.000
K43 Ventral hernia
0.792 0.208 0.000
R52.9 Pain, unspecified
0.791 0.209 0.000
M13 Other arthritis
0.791 0.209 0.000
H53-H54 Visual disturbances and blindness
0.789 0.211 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.787 0.213 0.000
J60-J70 Lung diseases due to external agents
0.786 0.214 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.785 0.215 0.000
R07.0 Pain in throat
0.785 0.215 0.000
N89 Other noninflammatory disorders of vagina
0.785 0.215 0.000
M72 Fibroblastic disorders
0.785 0.215 0.000
J90-J94 Other diseases of pleura
0.784 0.216 0.000
M40-M43 Deforming dorsopathies
0.784 0.216 0.000
J00-J06 Acute upper respiratory infections
0.784 0.216 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.783 0.217 0.000
J18 Pneumonia, organism unspecified
0.783 0.217 0.000
D60-D64 Aplastic and other anaemias
0.783 0.217 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.782 0.218 0.000
M75.9 Shoulder lesion, unspecified
0.782 0.218 0.000
G44 Other headache syndromes
0.781 0.219 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.780 0.220 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.780 0.220 0.000
A00-A09 Intestinal infectious diseases
0.778 0.222 0.000
B37 Candidiasis
0.777 0.223 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.777 0.223 0.000
F80-F89 Disorders of psychological development
0.777 0.223 0.000
I49.9 Cardiac arrhythmia, unspecified
0.776 0.224 0.000
R61 Hyperhidrosis
0.776 0.224 0.000
J22 Unspecified acute lower respiratory infection
0.773 0.227 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.773 0.227 0.000
G40 Epilepsy
0.773 0.227 0.000
E50-E64 Other nutritional deficiencies
0.771 0.229 0.000
R63 Symptoms and signs concerning food and fluid intake
0.771 0.229 0.000
I47 Paroxysmal tachycardia
0.771 0.229 0.000
S50-S59 Injuries to the elbow and forearm
0.771 0.229 0.000
I33 Acute and subacute endocarditis
0.768 0.232 0.000
I35.1 Aortic (valve) insufficiency
0.768 0.232 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.768 0.232 0.000
D00-D09 In situ neoplasms
0.768 0.232 0.000
S90-S99 Injuries to the ankle and foot
0.767 0.233 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.767 0.233 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.767 0.233 0.000
N92 Excessive, frequent and irregular menstruation
0.766 0.234 0.000
C15-C26 Malignant neoplasms of digestive organs
0.765 0.235 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.764 0.236 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.763 0.237 0.000
H55-H59 Other disorders of eye and adnexa
0.763 0.237 0.000
M79.66 Pain in limb (Lower leg)
0.762 0.237 0.000
I05-I09 Chronic rheumatic heart diseases
0.762 0.238 0.000
N18.2 Chronic kidney disease, stage 2
0.762 0.238 0.000
M80-M85 Disorders of bone density and structure
0.762 0.238 0.000
I30 Acute pericarditis
0.762 0.238 0.000
S62 Fracture at wrist and hand level
0.757 0.242 0.000
M75.3 Calcific tendinitis of shoulder
0.757 0.243 0.000
K35.9 Acute appendicitis, unspecified
0.756 0.244 0.000
R45 Symptoms and signs involving emotional state
0.754 0.246 0.000
R52.2 Other chronic pain
0.753 0.247 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.753 0.247 0.000
N81.3 Complete uterovaginal prolapse
0.753 0.247 0.000
F99-F99 Unspecified mental disorder
0.752 0.248 0.000
I51.4 Myocarditis, unspecified
0.750 0.250 0.000
H43-H45 Disorders of vitreous body and globe
0.750 0.250 0.000
I51.9 Heart disease, unspecified
0.748 0.252 0.000
D70 Agranulocytosis
0.747 0.253 0.000
M47.9 Spondylosis, unspecified
0.746 0.254 0.000
I42.0 Dilated cardiomyopathy
0.746 0.254 0.000
R57 Shock, not elsewhere classified
0.746 0.254 0.000
N39.9 Disorder of urinary system, unspecified
0.746 0.254 0.000
R06.4 Hyperventilation
0.746 0.254 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.744 0.256 0.000
N36 Other disorders of urethra
0.744 0.256 0.000
S68 Traumatic amputation of wrist and hand
0.743 0.257 0.000
C80 Malignant neoplasm without specification of site
0.743 0.257 0.000
R41.2 Retrograde amnesia
0.743 0.257 0.000
I65.2 Occlusion and stenosis of carotid artery
0.743 0.257 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.742 0.258 0.000
G30-G32 Other degenerative diseases of the nervous system
0.741 0.259 0.000
T66-T78 Other and unspecified effects of external causes
0.740 0.260 0.000
M75.5 Bursitis of shoulder
0.739 0.261 0.000
R59.1 Generalised enlarged lymph nodes
0.739 0.261 0.000
E10-E14 Diabetes mellitus
0.737 0.263 0.000
I31 Other diseases of pericardium
0.737 0.263 0.000
J42 Unspecified chronic bronchitis
0.737 0.263 0.000
I51.7 Cardiomegaly
0.736 0.263 0.000
R05 Cough
0.736 0.264 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.735 0.265 0.000
M06 Other rheumatoid arthritis
0.735 0.265 0.000
I67 Other cerebrovascular diseases
0.733 0.266 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.733 0.267 0.000
R07.1 Chest pain on breathing
0.732 0.268 0.000
R06.8 Other and unspecified abnormalities of breathing
0.732 0.268 0.000
I44.1 Atrioventricular block, second degree
0.732 0.268 0.000
G70-G73 Diseases of myoneural junction and muscle
0.731 0.269 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.730 0.270 0.000
A41 Other septicaemia
0.729 0.271 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.728 0.272 0.000
F10.0 Acute intoxication
0.727 0.273 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.727 0.273 0.000
K42 Umbilical hernia
0.727 0.273 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.727 0.273 0.000
I62 Other nontraumatic intracranial haemorrhage
0.726 0.273 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.726 0.274 0.000
M19.98 Arthrosis, unspecified (Other)
0.726 0.274 0.000
G56.2 Lesion of ulnar nerve
0.726 0.274 0.000
N95 Menopausal and other perimenopausal disorders
0.726 0.274 0.000
B35 Dermatophytosis
0.725 0.275 0.000
I51.8 Other ill-defined heart diseases
0.725 0.275 0.000
H53 Visual disturbances
0.725 0.275 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.724 0.276 0.000
X60-X84 Intentional self-harm
0.723 0.277 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.723 0.277 0.000
Y57 Other and unspecified drugs and medicaments
0.723 0.277 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.723 0.277 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.722 0.278 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.722 0.278 0.000
C67 Malignant neoplasm of bladder
0.721 0.279 0.000
S00 Superficial injury of head
0.721 0.279 0.000
W19 Unspecified fall
0.720 0.280 0.000
S67 Crushing injury of wrist and hand
0.720 0.280 0.000
R52.0 Acute pain
0.720 0.280 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.720 0.280 0.000
Y43 Primarily systemic agents
0.719 0.281 0.000
G56.0 Carpal tunnel syndrome
0.719 0.281 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.718 0.282 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.718 0.282 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
M76 Enthesopathies of lower limb, excluding foot
0.717 0.283 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.717 0.283 0.000
M71 Other bursopathies
0.717 0.283 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.716 0.284 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.716 0.284 0.000
C32 Malignant neoplasm of larynx
0.716 0.284 0.000
C31 Malignant neoplasm of accessory sinuses
0.716 0.284 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.716 0.284 0.000
C37 Malignant neoplasm of thymus
0.716 0.284 0.000
C33 Malignant neoplasm of trachea
0.716 0.284 0.000
C34.8 Overlapping lesion of bronchus and lung
0.715 0.285 0.000
C34.2 Middle lobe, bronchus or lung
0.715 0.285 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.715 0.285 0.000
R68 Other general symptoms and signs
0.714 0.286 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.714 0.286 0.000
R62 Lack of expected normal physiological development
0.714 0.286 0.000
R64 Cachexia
0.714 0.286 0.000
R58 Haemorrhage, not elsewhere classified
0.714 0.286 0.000
M54 Dorsalgia
0.714 0.286 0.000
N17.8 Other acute renal failure
0.714 0.286 0.000
N17.2 Acute renal failure with medullary necrosis
0.714 0.286 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.714 0.286 0.000
N17.0 Acute renal failure with tubular necrosis
0.714 0.286 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.714 0.286 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.714 0.286 0.000
M15 Polyarthrosis
0.714 0.286 0.000
I63.8 Other cerebral infarction
0.714 0.286 0.000
R41.0 Disorientation, unspecified
0.714 0.286 0.000
I52 Other heart disorders in diseases classified elsewhere
0.713 0.286 0.000
I48 Atrial fibrillation and flutter
0.713 0.286 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.713 0.286 0.000
I41 Myocarditis in diseases classified elsewhere
0.713 0.286 0.000
I40 Acute myocarditis
0.713 0.286 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.713 0.286 0.000
I37 Pulmonary valve disorders
0.713 0.286 0.000
I36 Nonrheumatic tricuspid valve disorders
0.713 0.286 0.000
I32 Pericarditis in diseases classified elsewhere
0.713 0.286 0.000
S64.4 Injury of digital nerve of other finger
0.713 0.287 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.713 0.287 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.713 0.287 0.000
C79 Secondary malignant neoplasm of other sites
0.713 0.287 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.712 0.288 0.000
W20-W49 Exposure to inanimate mechanical forces
0.712 0.288 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.711 0.289 0.000
M19.8 Other specified arthrosis
0.711 0.289 0.000
M19.2 Other secondary arthrosis
0.711 0.289 0.000
M19.1 Posttraumatic arthrosis of other joints
0.711 0.289 0.000
R06.2 Wheezing
0.710 0.290 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.710 0.290 0.000
F70-F79 Mental retardation
0.710 0.290 0.000
F60-F69 Disorders of adult personality and behaviour
0.710 0.290 0.000
S61.1 Open wound of finger(s) with damage to nail
0.710 0.290 0.000
Y40 Systemic antibiotics
0.708 0.292 0.000
E88 Other metabolic disorders
0.708 0.292 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.707 0.293 0.000
M75.8 Other shoulder lesions
0.707 0.293 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.707 0.293 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.707 0.293 0.000
M79.60 Pain in limb (Multiple sites)
0.707 0.293 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.706 0.294 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.705 0.295 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.704 0.296 0.000
R20 Disturbances of skin sensation
0.704 0.296 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.703 0.297 0.000
R46 Symptoms and signs involving appearance and behaviour
0.703 0.297 0.000
R43 Disturbances of smell and taste
0.703 0.297 0.000
C92 Myeloid leukaemia
0.703 0.297 0.000
N18.8 Other chronic renal failure
0.703 0.297 0.000
N18.5 Chronic kidney disease, stage 5
0.703 0.297 0.000
N18.1 Chronic kidney disease, stage 1
0.703 0.297 0.000
N18.0 End-stage renal disease
0.703 0.297 0.000
S70-S79 Injuries to the hip and thigh
0.702 0.297 0.000
R06.7 Sneezing
0.702 0.297 0.000
R06.6 Hiccough
0.702 0.297 0.000
R06.3 Periodic breathing
0.702 0.297 0.000
R06.1 Stridor
0.702 0.297 0.000
B37.0 Candidal stomatitis
0.702 0.298 0.000
M79.9 Soft tissue disorder, unspecified
0.702 0.298 0.000
M79.5 Residual foreign body in soft tissue
0.702 0.298 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.702 0.298 0.000
M79.3 Panniculitis, unspecified
0.702 0.298 0.000
M79.2 Neuralgia and neuritis, unspecified
0.702 0.298 0.000
M79.1 Myalgia
0.702 0.298 0.000
D80-D89 Certain disorders involving the immune mechanism
0.701 0.298 0.000
N86 Erosion and ectropion of cervix uteri
0.701 0.299 0.000
C53 Malignant neoplasm of cervix uteri
0.701 0.299 0.000
M47.8 Other spondylosis
0.701 0.299 0.000
N10-N16 Renal tubulo-interstitial diseases
0.701 0.299 0.000
M19.94 Arthrosis, unspecified (Hand)
0.701 0.299 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.701 0.299 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.699 0.301 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.699 0.301 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.699 0.301 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.699 0.301 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.699 0.301 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.699 0.301 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.699 0.301 0.000
F11 Mental and behavioural disorders due to use of opioids
0.699 0.301 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.699 0.301 0.000
S69 Other and unspecified injuries of wrist and hand
0.698 0.301 0.000
S65 Injury of blood vessels at wrist and hand level
0.698 0.301 0.000
S60 Superficial injury of wrist and hand
0.698 0.301 0.000
N37 Urethral disorders in diseases classified elsewhere
0.697 0.303 0.000
N34 Urethritis and urethral syndrome
0.697 0.303 0.000
N33 Bladder disorders in diseases classified elsewhere
0.697 0.303 0.000
M13.9 Arthritis, unspecified
0.696 0.304 0.000
J98 Other respiratory disorders
0.695 0.305 0.000
M48 Other spondylopathies
0.694 0.306 0.000
E40-E46 Malnutrition
0.693 0.307 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.693 0.307 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.693 0.307 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.693 0.307 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.693 0.307 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.693 0.307 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.693 0.307 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.693 0.307 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.693 0.307 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.693 0.307 0.000
T36 Poisoning by systemic antibiotics
0.693 0.307 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.692 0.308 0.000
N95.2 Postmenopausal atrophic vaginitis
0.690 0.310 0.000
Chapter XXII Codes for special purposes
0.690 0.310 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.689 0.311 0.000
G41 Status epilepticus
0.689 0.311 0.000
N39.4 Other specified urinary incontinence
0.688 0.312 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.687 0.313 0.000
E23 Hypofunction and other disorders of pituitary gland
0.687 0.313 0.000
N32 Other disorders of bladder
0.687 0.313 0.000
B15-B19 Viral hepatitis
0.687 0.313 0.000
M86-M90 Other osteopathies
0.686 0.314 0.000
T51 Toxic effect of alcohol
0.686 0.314 0.000
N20.0 Calculus of kidney
0.686 0.314 0.000
V20-V29 Motorcycle rider injured in transport accident
0.686 0.314 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.685 0.314 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.685 0.315 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.685 0.315 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.684 0.315 0.000
J18.1 Lobar pneumonia, unspecified
0.684 0.316 0.000
G91 Hydrocephalus
0.684 0.316 0.000
N30 Cystitis
0.684 0.316 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.684 0.316 0.000
N81.8 Other female genital prolapse
0.683 0.317 0.000
W13 Fall from, out of or through building or structure
0.683 0.317 0.000
N39.2 Orthostatic proteinuria, unspecified
0.682 0.317 0.000
N39.1 Persistent proteinuria, unspecified
0.682 0.317 0.000
T42.4 Benzodiazepines
0.682 0.318 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.682 0.318 0.000
D55-D59 Haemolytic anaemias
0.682 0.318 0.000
Y52 Agents primarily affecting the cardiovascular system
0.681 0.318 0.000
T40.2 Other opioids
0.681 0.319 0.000
S08 Traumatic amputation of part of head
0.681 0.319 0.000
S07 Crushing injury of head
0.681 0.319 0.000
S06 Intracranial injury
0.681 0.319 0.000
S05 Injury of eye and orbit
0.681 0.319 0.000
S04 Injury of cranial nerves
0.681 0.319 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.681 0.319 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.681 0.319 0.000
G83 Other paralytic syndromes
0.680 0.319 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.679 0.320 0.000
Y35-Y36 Legal intervention and operations of war
0.679 0.320 0.000
Y10-Y34 Event of undetermined intent
0.679 0.320 0.000
Y00-Y09 Assault
0.679 0.320 0.000
X85-X99 Assault
0.679 0.320 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.679 0.320 0.000
X50-X57 Overexertion, travel and privation
0.679 0.320 0.000
X30-X39 Exposure to forces of nature
0.679 0.320 0.000
X20-X29 Contact with venomous animals and plants
0.679 0.320 0.000
X10-X19 Contact with heat and hot substances
0.679 0.320 0.000
X00-X09 Exposure to smoke, fire and flames
0.679 0.320 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.679 0.320 0.000
W75-W84 Other accidental threats to breathing
0.679 0.320 0.000
W65-W74 Accidental drowning and submersion
0.679 0.320 0.000
W50-W64 Exposure to animate mechanical forces
0.679 0.320 0.000
V98-V99 Other and unspecified transport accidents
0.679 0.320 0.000
V95-V97 Air and space transport accidents
0.679 0.320 0.000
V90-V94 Water transport accidents
0.679 0.320 0.000
V80-V89 Other land transport accidents
0.679 0.320 0.000
V70-V79 Bus occupant injured in transport accident
0.679 0.320 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.679 0.320 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.679 0.320 0.000
V40-V49 Car occupant injured in transport accident
0.679 0.320 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.679 0.320 0.000
V01-V09 Pedestrian injured in transport accident
0.679 0.320 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.679 0.321 0.000
C56 Malignant neoplasm of ovary
0.679 0.321 0.000
G95 Other diseases of spinal cord
0.679 0.321 0.000
D68.2 Hereditary deficiency of other clotting factors
0.679 0.321 0.000
N39.8 Other specified disorders of urinary system
0.679 0.321 0.000
N60-N64 Disorders of breast
0.678 0.322 0.000
R40 Somnolence, stupor and coma
0.677 0.322 0.000
I46 Cardiac arrest
0.677 0.323 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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