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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74635050
log Bayes Factor = 15.419
Chromosome 6   position 19,632,865  (GRCh37) Explore rs74635050 on Ensembl!
Variant rs74635050 is part of Cluster X0146

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
N30-N39 Other diseases of urinary system
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
F30-F39 Mood [affective] disorders
0.997 0.003 0.000
S00-S09 Injuries to the head
0.994 0.006 0.000
F32 Depressive episode
0.993 0.007 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.989 0.011 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.988 0.012 0.000
N30 Cystitis
0.988 0.012 0.000
F32.9 Depressive episode, unspecified
0.983 0.017 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.980 0.020 0.000
N39 Other disorders of urinary system
0.980 0.020 0.000
M50-M54 Other dorsopathies
0.979 0.021 0.000
R50-R69 General symptoms and signs
0.976 0.024 0.000
N60-N64 Disorders of breast
0.975 0.025 0.000
N32 Other disorders of bladder
0.968 0.032 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.967 0.033 0.000
G90-G99 Other disorders of the nervous system
0.963 0.037 0.000
Chapter VII Diseases of the eye and adnexa
0.963 0.037 0.000
N32.8 Other specified disorders of bladder
0.961 0.039 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.959 0.041 0.000
R51 Headache
0.959 0.041 0.000
M50 Cervical disk disorders
0.954 0.046 0.000
Chapter II Neoplasms
0.951 0.049 0.000
T39.1 4-Aminophenol derivatives
0.949 0.051 0.000
N30.2 Other chronic cystitis
0.948 0.052 0.000
S01 Open wound of head
0.935 0.065 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.934 0.066 0.000
Chapter IX Diseases of the circulatory system
0.933 0.067 0.000
M20-M25 Other joint disorders
0.932 0.068 0.000
S00 Superficial injury of head
0.928 0.072 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.928 0.072 0.000
N60 Benign mammary dysplasia
0.928 0.072 0.000
Chapter XX External causes of morbidity and mortality
0.926 0.074 0.000
Chapter VIII Diseases of the ear and mastoid process
0.926 0.074 0.000
I30-I52 Other forms of heart disease
0.926 0.074 0.000
N39.0 Urinary tract infection, site not specified
0.919 0.081 0.000
N40-N51 Diseases of male genital organs
0.916 0.084 0.000
S06 Intracranial injury
0.910 0.090 0.000
N63 Unspecified lump in breast
0.906 0.094 0.000
M54 Dorsalgia
0.904 0.096 0.000
M50.1 Cervical disk disorder with radiculopathy
0.900 0.100 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.897 0.103 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.890 0.110 0.000
N39.9 Disorder of urinary system, unspecified
0.888 0.112 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.888 0.112 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.887 0.113 0.000
I31 Other diseases of pericardium
0.885 0.115 0.000
F31 Bipolar affective disorder
0.884 0.116 0.000
R52 Pain, not elsewhere classified
0.881 0.119 0.000
I49 Other cardiac arrhythmias
0.878 0.122 0.000
R11 Nausea and vomiting
0.878 0.122 0.000
S60-S69 Injuries to the wrist and hand
0.877 0.123 0.000
Chapter I Certain infectious and parasitic diseases
0.876 0.124 0.000
T81 Complications of procedures, not elsewhere classified
0.875 0.125 0.000
R47-R49 Symptoms and signs involving speech and voice
0.873 0.127 0.000
R60 Oedema, not elsewhere classified
0.869 0.131 0.000
N30.8 Other cystitis
0.869 0.131 0.000
M25 Other joint disorders, not elsewhere classified
0.868 0.132 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.867 0.133 0.000
N41 Inflammatory diseases of prostate
0.867 0.133 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.867 0.133 0.000
F33 Recurrent depressive disorder
0.866 0.134 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.865 0.135 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.860 0.140 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.857 0.143 0.000
R21 Rash and other nonspecific skin eruption
0.855 0.145 0.000
D10-D36 Benign neoplasms
0.855 0.145 0.000
I31.3 Pericardial effusion (noninflammatory)
0.854 0.146 0.000
S01.0 Open wound of scalp
0.849 0.151 0.000
D00-D09 In situ neoplasms
0.848 0.152 0.000
I60-I69 Cerebrovascular diseases
0.843 0.157 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.841 0.158 0.000
R15 Faecal incontinence
0.841 0.159 0.000
G30-G32 Other degenerative diseases of the nervous system
0.838 0.162 0.000
R18 Ascites
0.836 0.164 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.834 0.166 0.000
N36 Other disorders of urethra
0.834 0.166 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.833 0.167 0.000
M54.3 Sciatica
0.830 0.170 0.000
S90-S99 Injuries to the ankle and foot
0.829 0.171 0.000
M50.0 Cervical disk disorder with myelopathy
0.828 0.172 0.000
N39.3 Stress incontinence
0.827 0.173 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.825 0.175 0.000
S01.9 Open wound of head, part unspecified
0.824 0.176 0.000
R17 Unspecified jaundice
0.822 0.178 0.000
G70-G73 Diseases of myoneural junction and muscle
0.821 0.178 0.000
S70-S79 Injuries to the hip and thigh
0.821 0.179 0.000
D22 Melanocytic naevi
0.820 0.180 0.000
M35 Other systemic involvement of connective tissue
0.819 0.181 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.819 0.181 0.000
N48 Other disorders of penis
0.818 0.182 0.000
N60.1 Diffuse cystic mastopathy
0.818 0.182 0.000
N30.9 Cystitis, unspecified
0.816 0.184 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.815 0.185 0.000
H90-H95 Other disorders of ear
0.813 0.187 0.000
I35 Nonrheumatic aortic valve disorders
0.813 0.187 0.000
D22.5 Melanocytic naevi of trunk
0.810 0.190 0.000
N41.1 Chronic prostatitis
0.810 0.190 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.810 0.190 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.810 0.190 0.000
S20-S29 Injuries to the thorax
0.809 0.191 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.807 0.193 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.805 0.195 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.803 0.197 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.803 0.197 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.803 0.197 0.000
W20-W49 Exposure to inanimate mechanical forces
0.802 0.198 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.801 0.199 0.000
N10-N16 Renal tubulo-interstitial diseases
0.800 0.200 0.000
H02 Other disorders of eyelid
0.794 0.206 0.000
R47 Speech disturbances, not elsewhere classified
0.793 0.207 0.000
M54.9 Dorsalgia, unspecified
0.793 0.207 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.791 0.209 0.000
G81 Hemiplegia
0.787 0.213 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.786 0.214 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.786 0.214 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.785 0.215 0.000
R53 Malaise and fatigue
0.783 0.217 0.000
H55-H59 Other disorders of eye and adnexa
0.783 0.217 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.782 0.218 0.000
H65-H75 Diseases of middle ear and mastoid
0.779 0.221 0.000
S00.8 Superficial injury of other parts of head
0.779 0.221 0.000
G93 Other disorders of brain
0.778 0.222 0.000
D05 Carcinoma in situ of breast
0.776 0.224 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.774 0.226 0.000
A30-A49 Other bacterial diseases
0.774 0.226 0.000
N35 Urethral stricture
0.774 0.226 0.000
R50 Fever of unknown origin
0.774 0.226 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.773 0.227 0.000
R60.0 Localised oedema
0.773 0.227 0.000
H30-H36 Disorders of choroid and retina
0.772 0.228 0.000
G90 Disorders of autonomic nervous system
0.771 0.229 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.771 0.229 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.770 0.230 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.770 0.230 0.000
S06.5 Traumatic subdural haemorrhage
0.770 0.230 0.000
M54.36 Sciatica (Lumbar region)
0.769 0.231 0.000
N00-N08 Glomerular diseases
0.767 0.233 0.000
G40-G47 Episodic and paroxysmal disorders
0.767 0.233 0.000
R52.1 Chronic intractable pain
0.767 0.233 0.000
M70-M79 Other soft tissue disorders
0.767 0.233 0.000
S00.1 Contusion of eyelid and periocular area
0.767 0.233 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.765 0.235 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.765 0.235 0.000
N60.8 Other benign mammary dysplasias
0.764 0.236 0.000
M21 Other acquired deformities of limbs
0.764 0.236 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.763 0.237 0.000
I49.0 Ventricular fibrillation and flutter
0.762 0.238 0.000
M25.5 Pain in joint
0.760 0.240 0.000
S61 Open wound of wrist and hand
0.760 0.240 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.760 0.240 0.000
T42.4 Benzodiazepines
0.760 0.240 0.000
M35.0 Sicca syndrome [Sjogren]
0.759 0.241 0.000
C51-C58 Malignant neoplasms of female genital organs
0.756 0.244 0.000
F31.9 Bipolar affective disorder, unspecified
0.756 0.244 0.000
G35 Multiple sclerosis
0.756 0.244 0.000
I51 Complications and ill-defined descriptions of heart disease
0.755 0.245 0.000
H10-H13 Disorders of conjunctiva
0.755 0.245 0.000
T88.4 Failed or difficult intubation
0.754 0.246 0.000
D32 Benign neoplasm of meninges
0.753 0.247 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.753 0.247 0.000
R61 Hyperhidrosis
0.752 0.248 0.000
R25 Abnormal involuntary movements
0.750 0.250 0.000
M91-M94 Chondropathies
0.749 0.251 0.000
M86-M90 Other osteopathies
0.749 0.251 0.000
I44 Atrioventricular and left bundle-branch block
0.745 0.255 0.000
M22 Disorders of patella
0.745 0.255 0.000
M50.3 Other cervical disk degeneration
0.745 0.255 0.000
B35-B49 Mycoses
0.745 0.255 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.745 0.255 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.744 0.256 0.000
N30.1 Interstitial cystitis (chronic)
0.744 0.256 0.000
M54.4 Lumbago with sciatica
0.744 0.256 0.000
H53-H54 Visual disturbances and blindness
0.744 0.256 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.744 0.256 0.000
R27 Other lack of coordination
0.743 0.257 0.000
S50-S59 Injuries to the elbow and forearm
0.742 0.258 0.000
S02 Fracture of skull and facial bones
0.742 0.258 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.740 0.260 0.000
R56 Convulsions, not elsewhere classified
0.738 0.261 0.000
T86 Failure and rejection of transplanted organs and tissues
0.738 0.262 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.737 0.263 0.000
I49.8 Other specified cardiac arrhythmias
0.736 0.264 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.736 0.264 0.000
I49.5 Sick sinus syndrome
0.735 0.265 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.735 0.265 0.000
S00.3 Superficial injury of nose
0.734 0.266 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.732 0.268 0.000
S00.9 Superficial injury of head, part unspecified
0.732 0.268 0.000
R54 Senility
0.732 0.268 0.000
R52.2 Other chronic pain
0.732 0.268 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.731 0.268 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.729 0.271 0.000
N60.4 Mammary duct ectasia
0.729 0.271 0.000
N39.4 Other specified urinary incontinence
0.728 0.272 0.000
I47 Paroxysmal tachycardia
0.728 0.272 0.000
M80-M85 Disorders of bone density and structure
0.725 0.275 0.000
D12.4 Descending colon
0.725 0.275 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.725 0.275 0.000
G91 Hydrocephalus
0.724 0.276 0.000
H60-H62 Diseases of external ear
0.724 0.276 0.000
X60-X84 Intentional self-harm
0.723 0.277 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.723 0.277 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.721 0.279 0.000
H92 Otalgia and effusion of ear
0.721 0.279 0.000
N60.3 Fibrosclerosis of breast
0.721 0.279 0.000
W00-W19 Falls
0.721 0.279 0.000
M25.4 Effusion of joint
0.719 0.281 0.000
M65-M68 Disorders of synovium and tendon
0.719 0.281 0.000
S01.5 Open wound of lip and oral cavity
0.718 0.282 0.000
N30.3 Trigonitis
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N37 Urethral disorders in diseases classified elsewhere
0.717 0.283 0.000
N34 Urethritis and urethral syndrome
0.717 0.283 0.000
N33 Bladder disorders in diseases classified elsewhere
0.717 0.283 0.000
I69 Sequelae of cerebrovascular disease
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
S06.8 Other intracranial injuries
0.716 0.284 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.716 0.284 0.000
S80-S89 Injuries to the knee and lower leg
0.716 0.284 0.000
F99-F99 Unspecified mental disorder
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F80-F89 Disorders of psychological development
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
F60-F69 Disorders of adult personality and behaviour
0.716 0.284 0.000
F38 Other mood [affective] disorders
0.715 0.285 0.000
F34 Persistent mood [affective] disorders
0.715 0.285 0.000
F30 Manic episode
0.715 0.285 0.000
F39 Unspecified mood [affective] disorder
0.715 0.285 0.000
M34 Systemic sclerosis
0.715 0.285 0.000
R12 Heartburn
0.715 0.285 0.000
G81.9 Hemiplegia, unspecified
0.715 0.285 0.000
H05 Disorders of orbit
0.714 0.286 0.000
M54.1 Radiculopathy
0.713 0.286 0.000
I46 Cardiac arrest
0.713 0.287 0.000
M50.2 Other cervical disk displacement
0.713 0.287 0.000
S08 Traumatic amputation of part of head
0.712 0.288 0.000
S07 Crushing injury of head
0.712 0.288 0.000
S05 Injury of eye and orbit
0.712 0.288 0.000
S04 Injury of cranial nerves
0.712 0.288 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.712 0.288 0.000
F32.8 Other depressive episodes
0.712 0.288 0.000
F32.1 Moderate depressive episode
0.712 0.288 0.000
F32.0 Mild depressive episode
0.712 0.288 0.000
Chapter XXII Codes for special purposes
0.712 0.288 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.711 0.289 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.710 0.290 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.709 0.291 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.709 0.291 0.000
M60-M63 Disorders of muscles
0.709 0.291 0.000
M00-M03 Infectious arthropathies
0.709 0.291 0.000
M24 Other specific joint derangements
0.709 0.291 0.000
T79-T79 Certain early complications of trauma
0.709 0.291 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.708 0.292 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.708 0.292 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.708 0.292 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.708 0.292 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.708 0.292 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.708 0.292 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.708 0.292 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.708 0.292 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.708 0.292 0.000
T36 Poisoning by systemic antibiotics
0.708 0.292 0.000
N30.4 Irradiation cystitis
0.708 0.292 0.000
N30.0 Acute cystitis
0.708 0.292 0.000
I05-I09 Chronic rheumatic heart diseases
0.708 0.292 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.707 0.293 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.706 0.294 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.704 0.296 0.000
I35.0 Aortic (valve) stenosis
0.703 0.297 0.000
T87 Complications peculiar to reattachment and amputation
0.703 0.297 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.703 0.297 0.000
N39.2 Orthostatic proteinuria, unspecified
0.702 0.298 0.000
N39.1 Persistent proteinuria, unspecified
0.702 0.298 0.000
M53 Other dorsopathies, not elsewhere classified
0.702 0.298 0.000
R68 Other general symptoms and signs
0.700 0.300 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.700 0.300 0.000
R62 Lack of expected normal physiological development
0.700 0.300 0.000
R57 Shock, not elsewhere classified
0.700 0.300 0.000
R64 Cachexia
0.700 0.300 0.000
R58 Haemorrhage, not elsewhere classified
0.700 0.300 0.000
H90 Conductive and sensorineural hearing loss
0.700 0.300 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.699 0.301 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.699 0.301 0.000
R50.0 Fever with chills
0.698 0.302 0.000
H25-H28 Disorders of lens
0.697 0.303 0.000
R23 Other skin changes
0.696 0.303 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.696 0.304 0.000
N48.1 Balanoposthitis
0.696 0.304 0.000
S99 Other and unspecified injuries of ankle and foot
0.696 0.304 0.000
N60.0 Solitary cyst of breast
0.696 0.304 0.000
D48.6 Breast
0.695 0.305 0.000
G70 Myasthenia gravis and other myoneural disorders
0.694 0.306 0.000
N32.4 Rupture of bladder, nontraumatic
0.694 0.306 0.000
N32.2 Vesical fistula, not elsewhere classified
0.694 0.306 0.000
N32.1 Vesicointestinal fistula
0.694 0.306 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.693 0.307 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.693 0.307 0.000
T39.4 Antirheumatics, not elsewhere classified
0.693 0.307 0.000
T39.2 Pyrazolone derivatives
0.693 0.307 0.000
T39.0 Salicylates
0.693 0.307 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.691 0.309 0.000
G96 Other disorders of central nervous system
0.691 0.309 0.000
G95 Other diseases of spinal cord
0.691 0.309 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.691 0.309 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.691 0.309 0.000
G92 Toxic encephalopathy
0.691 0.309 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.690 0.310 0.000
D10 Benign neoplasm of mouth and pharynx
0.690 0.310 0.000
T66-T78 Other and unspecified effects of external causes
0.690 0.310 0.000
S01.3 Open wound of ear
0.690 0.310 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.689 0.311 0.000
N99-N99 Other disorders of the genitourinary system
0.688 0.312 0.000
A41 Other septicaemia
0.688 0.312 0.000
G80 Infantile cerebral palsy
0.688 0.312 0.000
F33.9 Recurrent depressive disorder, unspecified
0.686 0.314 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.686 0.314 0.000
S00.0 Superficial injury of scalp
0.686 0.314 0.000
N45 Orchitis and epididymitis
0.686 0.314 0.000
H02.3 Blepharochalasis
0.685 0.314 0.000
D05.1 Intraductal carcinoma in situ
0.685 0.315 0.000
N61 Inflammatory disorders of breast
0.685 0.315 0.000
M50.9 Cervical disk disorder, unspecified
0.684 0.316 0.000
M50.8 Other cervical disk disorders
0.684 0.316 0.000
M51 Other intervertebral disk disorders
0.684 0.316 0.000
H02.6 Xanthelasma of eyelid
0.684 0.316 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.683 0.316 0.000
S01.2 Open wound of nose
0.682 0.318 0.000
I67 Other cerebrovascular diseases
0.682 0.318 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.682 0.318 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.682 0.318 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.682 0.318 0.000
N60.2 Fibroadenosis of breast
0.681 0.319 0.000
N64 Other disorders of breast
0.681 0.319 0.000
D32.0 Cerebral meninges
0.681 0.319 0.000
G20-G26 Extrapyramidal and movement disorders
0.680 0.320 0.000
H33 Retinal detachments and breaks
0.680 0.320 0.000
T93 Sequelae of injuries of lower limb
0.679 0.321 0.000
H72 Perforation of tympanic membrane
0.677 0.323 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.676 0.324 0.000
I49.9 Cardiac arrhythmia, unspecified
0.675 0.325 0.000
N13 Obstructive and reflux uropathy
0.675 0.325 0.000
D12.5 Sigmoid colon
0.675 0.325 0.000
N36.0 Urethral fistula
0.674 0.325 0.000
I44.7 Left bundle-branch block, unspecified
0.674 0.326 0.000
R60.9 Oedema, unspecified
0.674 0.326 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.673 0.327 0.000
H57 Other disorders of eye and adnexa
0.672 0.328 0.000
R16.0 Hepatomegaly, not elsewhere classified
0.671 0.328 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.671 0.329 0.000
N41.0 Acute prostatitis
0.671 0.329 0.000
S01.7 Multiple open wounds of head
0.670 0.329 0.000
S01.4 Open wound of cheek and temporomandibular area
0.670 0.329 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.670 0.330 0.000
D03 Melanoma in situ
0.670 0.330 0.000
I00-I02 Acute rheumatic fever
0.669 0.331 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.669 0.331 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.668 0.332 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.668 0.332 0.000
M33 Dermatopolymyositis
0.668 0.332 0.000
M32 Systemic lupus erythematosus
0.668 0.332 0.000
M30 Polyarteritis nodosa and related conditions
0.668 0.332 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.668 0.332 0.000
S27 Injury of other and unspecified intrathoracic organs
0.667 0.333 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.667 0.333 0.000
G93.8 Other specified disorders of brain
0.666 0.334 0.000
N75 Diseases of Bartholin's gland
0.666 0.334 0.000
M25.7 Osteophyte
0.666 0.334 0.000
S00.7 Multiple superficial injuries of head
0.665 0.334 0.000
S00.5 Superficial injury of lip and oral cavity
0.665 0.334 0.000
S00.4 Superficial injury of ear
0.665 0.334 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.665 0.334 0.000
R47.0 Dysphasia and aphasia
0.665 0.335 0.000
N60.9 Benign mammary dysplasia, unspecified
0.665 0.335 0.000
A00-A09 Intestinal infectious diseases
0.665 0.335 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.664 0.336 0.000
Y35-Y36 Legal intervention and operations of war
0.664 0.336 0.000
Y10-Y34 Event of undetermined intent
0.664 0.336 0.000
Y00-Y09 Assault
0.664 0.336 0.000
X85-X99 Assault
0.664 0.336 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.664 0.336 0.000
X50-X57 Overexertion, travel and privation
0.664 0.336 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.664 0.336 0.000
X30-X39 Exposure to forces of nature
0.664 0.336 0.000
X20-X29 Contact with venomous animals and plants
0.664 0.336 0.000
X10-X19 Contact with heat and hot substances
0.664 0.336 0.000
X00-X09 Exposure to smoke, fire and flames
0.664 0.336 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.664 0.336 0.000
W75-W84 Other accidental threats to breathing
0.664 0.336 0.000
W65-W74 Accidental drowning and submersion
0.664 0.336 0.000
W50-W64 Exposure to animate mechanical forces
0.664 0.336 0.000
V98-V99 Other and unspecified transport accidents
0.664 0.336 0.000
V95-V97 Air and space transport accidents
0.664 0.336 0.000
V90-V94 Water transport accidents
0.664 0.336 0.000
V80-V89 Other land transport accidents
0.664 0.336 0.000
V70-V79 Bus occupant injured in transport accident
0.664 0.336 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.664 0.336 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.664 0.336 0.000
V40-V49 Car occupant injured in transport accident
0.664 0.336 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.664 0.336 0.000
V20-V29 Motorcycle rider injured in transport accident
0.664 0.336 0.000
V01-V09 Pedestrian injured in transport accident
0.664 0.336 0.000
R94 Abnormal results of function studies
0.664 0.336 0.000
I52 Other heart disorders in diseases classified elsewhere
0.664 0.336 0.000
I48 Atrial fibrillation and flutter
0.664 0.336 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.664 0.336 0.000
I41 Myocarditis in diseases classified elsewhere
0.664 0.336 0.000
I40 Acute myocarditis
0.664 0.336 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.664 0.336 0.000
I37 Pulmonary valve disorders
0.664 0.336 0.000
I36 Nonrheumatic tricuspid valve disorders
0.664 0.336 0.000
I33 Acute and subacute endocarditis
0.664 0.336 0.000
I32 Pericarditis in diseases classified elsewhere
0.664 0.336 0.000
I30 Acute pericarditis
0.664 0.336 0.000
I38 Endocarditis, valve unspecified
0.663 0.337 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.663 0.337 0.000
G62 Other polyneuropathies
0.662 0.338 0.000
D48.1 Connective and other soft tissue
0.662 0.338 0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.661 0.339 0.000
I35.8 Other aortic valve disorders
0.660 0.340 0.000
R47.8 Other and unspecified speech disturbances
0.660 0.340 0.000
M40-M43 Deforming dorsopathies
0.659 0.341 0.000
I49.4 Other and unspecified premature depolarisation
0.659 0.341 0.000
I45 Other conduction disorders
0.659 0.341 0.000
N48.4 Impotence of organic origin
0.659 0.341 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.659 0.341 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.658 0.341 0.000
R20 Disturbances of skin sensation
0.658 0.342 0.000
N36.8 Other specified disorders of urethra
0.657 0.342 0.000
N50 Other disorders of male genital organs
0.657 0.343 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.657 0.343 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.657 0.343 0.000
N46 Male infertility
0.657 0.343 0.000
N44 Torsion of testis
0.657 0.343 0.000
M25.8 Other specified joint disorders
0.656 0.344 0.000
D12.0 Caecum
0.656 0.344 0.000
H92.0 Otalgia
0.656 0.344 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.655 0.345 0.000
W25 Contact with sharp glass
0.655 0.345 0.000
D26 Other benign neoplasms of uterus
0.655 0.345 0.000
S06.9 Intracranial injury, unspecified
0.653 0.347 0.000
S06.7 Intracranial injury with prolonged coma
0.653 0.347 0.000
S06.4 Epidural haemorrhage
0.653 0.347 0.000
S06.3 Focal brain injury
0.653 0.347 0.000
S06.2 Diffuse brain injury
0.653 0.347 0.000
S06.1 Traumatic cerebral oedema
0.653 0.347 0.000
S06.0 Concussion
0.653 0.347 0.000
C07 Malignant neoplasm of parotid gland
0.651 0.349 0.000
B37 Candidiasis
0.651 0.349 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.650 0.350 0.000
D12.8 Rectum
0.650 0.350 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.650 0.350 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.649 0.351 0.000
R16.1 Splenomegaly, not elsewhere classified
0.649 0.351 0.000
I51.8 Other ill-defined heart diseases
0.649 0.351 0.000
I31.9 Disease of pericardium, unspecified
0.648 0.352 0.000
D04 Carcinoma in situ of skin
0.648 0.352 0.000
M54.8 Other dorsalgia
0.648 0.352 0.000
M54.6 Pain in thoracic spine
0.648 0.352 0.000
M54.0 Panniculitis affecting regions of neck and back
0.648 0.352 0.000
C73 Malignant neoplasm of thyroid gland
0.647 0.353 0.000
S01.1 Open wound of eyelid and periocular area
0.647 0.353 0.000
F20 Schizophrenia
0.647 0.353 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.645 0.355 0.000
W22 Striking against or struck by other objects
0.644 0.356 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.643 0.357 0.000
G58 Other mononeuropathies
0.643 0.357 0.000
S60 Superficial injury of wrist and hand
0.643 0.357 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.643 0.357 0.000
D46 Myelodysplastic syndromes
0.643 0.357 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.643 0.357 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.643 0.357 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.643 0.357 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.643 0.357 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.643 0.357 0.000
H80-H83 Diseases of inner ear
0.643 0.357 0.000
S70 Superficial injury of hip and thigh
0.642 0.358 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.642 0.358 0.000
S72 Fracture of femur
0.639 0.361 0.000
N42 Other disorders of prostate
0.637 0.363 0.000
G40 Epilepsy
0.637 0.363 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.636 0.364 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.636 0.364 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.636 0.364 0.000
G83 Other paralytic syndromes
0.636 0.364 0.000
G82 Paraplegia and tetraplegia
0.636 0.364 0.000
S64 Injury of nerves at wrist and hand level
0.635 0.364 0.000
H18 Other disorders of cornea
0.635 0.365 0.000
I31.8 Other specified diseases of pericardium
0.634 0.366 0.000
I31.2 Haemopericardium, not elsewhere classified
0.634 0.366 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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