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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74677747
log Bayes Factor = 15.6294
Chromosome 10   position 130,448,931  (GRCh37) Explore rs74677747 on Ensembl!
Variant rs74677747 is part of Cluster X0039

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
J40-J47 Chronic lower respiratory diseases
0.997 0.003 0.000
J44 Other chronic obstructive pulmonary disease
0.997 0.003 0.000
N18 Chronic renal failure
0.997 0.003 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.995 0.005 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.988 0.012 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.984 0.016 0.000
C15-C26 Malignant neoplasms of digestive organs
0.983 0.017 0.000
N18.3 Chronic kidney disease, stage 3
0.982 0.018 0.000
M70-M79 Other soft tissue disorders
0.978 0.022 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.977 0.023 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.975 0.025 0.000
M50-M54 Other dorsopathies
0.973 0.027 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.972 0.028 0.000
Chapter XX External causes of morbidity and mortality
0.968 0.032 0.000
M54 Dorsalgia
0.967 0.033 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.966 0.034 0.000
M75 Shoulder lesions
0.966 0.034 0.000
E70-E90 Metabolic disorders
0.963 0.037 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.960 0.040 0.000
N10-N16 Renal tubulo-interstitial diseases
0.955 0.045 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.949 0.051 0.000
N17 Acute renal failure
0.941 0.059 0.000
M75.0 Adhesive capsulitis of shoulder
0.939 0.061 0.000
C25 Malignant neoplasm of pancreas
0.939 0.061 0.000
I30-I52 Other forms of heart disease
0.936 0.064 0.000
S40-S49 Injuries to the shoulder and upper arm
0.936 0.064 0.000
M54.5 Low back pain
0.933 0.067 0.000
N30-N39 Other diseases of urinary system
0.925 0.075 0.000
I50 Heart failure
0.920 0.080 0.000
D60-D64 Aplastic and other anaemias
0.918 0.082 0.000
N18.9 Chronic renal failure, unspecified
0.915 0.085 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.909 0.091 0.000
C60-C63 Malignant neoplasms of male genital organs
0.904 0.096 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.903 0.097 0.000
N17.9 Acute renal failure, unspecified
0.899 0.101 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.897 0.103 0.000
Chapter VIII Diseases of the ear and mastoid process
0.896 0.104 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.894 0.106 0.000
N20-N23 Urolithiasis
0.890 0.110 0.000
I05-I09 Chronic rheumatic heart diseases
0.890 0.110 0.000
I74 Arterial embolism and thrombosis
0.889 0.111 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.888 0.112 0.000
C25.9 Pancreas, unspecified
0.887 0.113 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.882 0.118 0.000
J43 Emphysema
0.880 0.120 0.000
I50.9 Heart failure, unspecified
0.877 0.123 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.876 0.124 0.000
C78.7 Secondary malignant neoplasm of liver
0.875 0.125 0.000
N19 Unspecified renal failure
0.875 0.125 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.875 0.125 0.000
C18 Malignant neoplasm of colon
0.874 0.126 0.000
D80-D89 Certain disorders involving the immune mechanism
0.871 0.129 0.000
M54.56 Low back pain (Lumbar region)
0.870 0.130 0.000
I60-I69 Cerebrovascular diseases
0.870 0.130 0.000
E87.6 Hypokalaemia
0.867 0.133 0.000
M75.1 Rotator cuff syndrome
0.863 0.137 0.000
M86-M90 Other osteopathies
0.857 0.143 0.000
S42 Fracture of shoulder and upper arm
0.855 0.145 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.854 0.146 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.852 0.148 0.000
S50-S59 Injuries to the elbow and forearm
0.851 0.149 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.849 0.151 0.000
C50-C50 Malignant neoplasm of breast
0.847 0.153 0.000
M54.3 Sciatica
0.845 0.154 0.000
C79 Secondary malignant neoplasm of other sites
0.842 0.158 0.000
M54.1 Radiculopathy
0.841 0.159 0.000
N00-N08 Glomerular diseases
0.841 0.159 0.000
C61 Malignant neoplasm of prostate
0.841 0.159 0.000
I71 Aortic aneurysm and dissection
0.838 0.162 0.000
M40-M43 Deforming dorsopathies
0.837 0.162 0.000
M20-M25 Other joint disorders
0.834 0.166 0.000
M54.57 Low back pain (Lumbosacral region)
0.833 0.167 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.832 0.168 0.000
N18.0 End-stage renal disease
0.831 0.169 0.000
N13 Obstructive and reflux uropathy
0.828 0.172 0.000
S00-S09 Injuries to the head
0.827 0.173 0.000
N18.2 Chronic kidney disease, stage 2
0.825 0.175 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.824 0.176 0.000
M45-M49 Spondylopathies
0.821 0.179 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.820 0.180 0.000
E87.3 Alkalosis
0.820 0.180 0.000
I72 Other aneurysm
0.819 0.181 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.819 0.181 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.816 0.184 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.816 0.184 0.000
M65-M68 Disorders of synovium and tendon
0.814 0.186 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.812 0.188 0.000
I50.0 Congestive heart failure
0.812 0.188 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.810 0.190 0.000
Y95 Nosocomial condition
0.808 0.192 0.000
C16 Malignant neoplasm of stomach
0.803 0.197 0.000
D86 Sarcoidosis
0.800 0.200 0.000
N72 Inflammatory disease of cervix uteri
0.800 0.200 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.799 0.201 0.000
C78.0 Secondary malignant neoplasm of lung
0.798 0.202 0.000
M54.2 Cervicalgia
0.798 0.202 0.000
J43.9 Emphysema, unspecified
0.796 0.204 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.795 0.205 0.000
M75.5 Bursitis of shoulder
0.795 0.205 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.792 0.208 0.000
M71 Other bursopathies
0.791 0.209 0.000
Chapter XXII Codes for special purposes
0.791 0.209 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.791 0.209 0.000
N36 Other disorders of urethra
0.788 0.212 0.000
C78.2 Secondary malignant neoplasm of pleura
0.788 0.212 0.000
N99-N99 Other disorders of the genitourinary system
0.788 0.212 0.000
J95-J99 Other diseases of the respiratory system
0.786 0.214 0.000
E83 Disorders of mineral metabolism
0.786 0.214 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.784 0.216 0.000
D63.0 Anaemia in neoplastic disease
0.782 0.218 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.781 0.219 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.779 0.221 0.000
J90-J94 Other diseases of pleura
0.779 0.221 0.000
Chapter XI Diseases of the digestive system
0.779 0.221 0.000
H65-H75 Diseases of middle ear and mastoid
0.779 0.221 0.000
C77.3 Axillary and upper limb lymph nodes
0.778 0.222 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.778 0.222 0.000
I08 Multiple valve diseases
0.778 0.222 0.000
C25.0 Head of pancreas
0.777 0.223 0.000
J00-J06 Acute upper respiratory infections
0.775 0.225 0.000
M75.3 Calcific tendinitis of shoulder
0.775 0.225 0.000
J60-J70 Lung diseases due to external agents
0.775 0.225 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.774 0.226 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.774 0.226 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.773 0.227 0.000
I77 Other disorders of arteries and arterioles
0.771 0.229 0.000
Chapter I Certain infectious and parasitic diseases
0.771 0.229 0.000
E86 Volume depletion
0.770 0.230 0.000
N40-N51 Diseases of male genital organs
0.770 0.230 0.000
N20 Calculus of kidney and ureter
0.768 0.232 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.766 0.234 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.764 0.235 0.000
C21 Malignant neoplasm of anus and anal canal
0.764 0.236 0.000
S00 Superficial injury of head
0.762 0.238 0.000
D62 Acute posthaemorrhagic anaemia
0.762 0.238 0.000
I42 Cardiomyopathy
0.761 0.239 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.761 0.239 0.000
E10-E14 Diabetes mellitus
0.760 0.240 0.000
N21 Calculus of lower urinary tract
0.760 0.240 0.000
C15 Malignant neoplasm of oesophagus
0.760 0.240 0.000
M54.39 Sciatica (Site unspecified)
0.758 0.242 0.000
Y84.2 Radiological procedure and radiotherapy
0.757 0.243 0.000
I44 Atrioventricular and left bundle-branch block
0.756 0.244 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.754 0.246 0.000
C18.0 Caecum
0.753 0.247 0.000
I50.1 Left ventricular failure
0.753 0.247 0.000
I67 Other cerebrovascular diseases
0.753 0.247 0.000
I26 Pulmonary embolism
0.752 0.248 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.751 0.249 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.750 0.250 0.000
S42.0 Fracture of clavicle
0.749 0.251 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.749 0.251 0.000
M91-M94 Chondropathies
0.747 0.253 0.000
M80-M85 Disorders of bone density and structure
0.745 0.255 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.745 0.255 0.000
I38 Endocarditis, valve unspecified
0.744 0.256 0.000
D86.0 Sarcoidosis of lung
0.743 0.257 0.000
I30 Acute pericarditis
0.742 0.258 0.000
D00-D09 In situ neoplasms
0.742 0.258 0.000
S52 Fracture of forearm
0.741 0.258 0.000
S70-S79 Injuries to the hip and thigh
0.740 0.260 0.000
C77.9 Lymph node, unspecified
0.739 0.260 0.000
C50 Malignant neoplasm of breast
0.738 0.262 0.000
D10-D36 Benign neoplasms
0.738 0.262 0.000
H90-H95 Other disorders of ear
0.736 0.264 0.000
S40 Superficial injury of shoulder and upper arm
0.735 0.265 0.000
S42.4 Fracture of lower end of humerus
0.733 0.267 0.000
C34 Malignant neoplasm of bronchus and lung
0.732 0.268 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.732 0.268 0.000
E50-E64 Other nutritional deficiencies
0.730 0.269 0.000
S32 Fracture of lumbar spine and pelvis
0.729 0.271 0.000
Chapter V Mental and behavioural disorders
0.728 0.272 0.000
I78 Diseases of capillaries
0.727 0.273 0.000
S10-S19 Injuries to the neck
0.726 0.274 0.000
M54.6 Pain in thoracic spine
0.724 0.276 0.000
C18.9 Colon, unspecified
0.724 0.276 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.723 0.277 0.000
N18.4 Chronic kidney disease, stage 4
0.722 0.277 0.000
V10-V19 Pedal cyclist injured in transport accident
0.722 0.278 0.000
M47 Spondylosis
0.722 0.278 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.721 0.279 0.000
E78.0 Pure hypercholesterolaemia
0.721 0.279 0.000
E87.0 Hyperosmolality and hypernatraemia
0.720 0.280 0.000
N03 Chronic nephritic syndrome
0.719 0.281 0.000
J81 Pulmonary oedema
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
D61 Other aplastic anaemias
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.283 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.716 0.284 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.716 0.284 0.000
J41 Simple and mucopurulent chronic bronchitis
0.715 0.285 0.000
J42 Unspecified chronic bronchitis
0.715 0.285 0.000
N18.8 Other chronic renal failure
0.715 0.285 0.000
N18.1 Chronic kidney disease, stage 1
0.715 0.285 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.715 0.285 0.000
C77.1 Intrathoracic lymph nodes
0.714 0.286 0.000
I07 Rheumatic tricuspid valve diseases
0.714 0.286 0.000
C77.0 Lymph nodes of head, face and neck
0.714 0.286 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.713 0.287 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.713 0.287 0.000
N34 Urethritis and urethral syndrome
0.712 0.288 0.000
J80 Adult respiratory distress syndrome
0.712 0.288 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.712 0.288 0.000
I61 Intracerebral haemorrhage
0.711 0.288 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.711 0.289 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.710 0.290 0.000
T79-T79 Certain early complications of trauma
0.710 0.290 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.708 0.292 0.000
I72.4 Aneurysm of artery of lower extremity
0.707 0.293 0.000
J92 Pleural plaque
0.706 0.294 0.000
T33-T35 Frostbite
0.705 0.295 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.705 0.295 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.705 0.295 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.705 0.295 0.000
T00-T07 Injuries involving multiple body regions
0.705 0.295 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.705 0.295 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.705 0.295 0.000
C17 Malignant neoplasm of small intestine
0.705 0.295 0.000
C23 Malignant neoplasm of gallbladder
0.705 0.295 0.000
C64-C68 Malignant neoplasms of urinary tract
0.703 0.297 0.000
M31 Other necrotising vasculopathies
0.703 0.297 0.000
I60 Subarachnoid haemorrhage
0.702 0.298 0.000
M76 Enthesopathies of lower limb, excluding foot
0.701 0.299 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.701 0.299 0.000
N39 Other disorders of urinary system
0.701 0.299 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.700 0.299 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.700 0.299 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.699 0.301 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.699 0.301 0.000
V20-V29 Motorcycle rider injured in transport accident
0.698 0.302 0.000
N18.5 Chronic kidney disease, stage 5
0.698 0.302 0.000
N71 Inflammatory disease of uterus, except cervix
0.698 0.302 0.000
M53 Other dorsopathies, not elsewhere classified
0.697 0.303 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.697 0.303 0.000
M43 Other deforming dorsopathies
0.697 0.303 0.000
E40-E46 Malnutrition
0.697 0.303 0.000
M54.16 Radiculopathy (Lumbar region)
0.697 0.303 0.000
N10 Acute tubulo-interstitial nephritis
0.696 0.304 0.000
E87.2 Acidosis
0.695 0.305 0.000
I44.7 Left bundle-branch block, unspecified
0.695 0.305 0.000
C50.4 Upper-outer quadrant of breast
0.694 0.306 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.694 0.306 0.000
Y35-Y36 Legal intervention and operations of war
0.694 0.306 0.000
Y10-Y34 Event of undetermined intent
0.694 0.306 0.000
Y00-Y09 Assault
0.694 0.306 0.000
X85-X99 Assault
0.694 0.306 0.000
X60-X84 Intentional self-harm
0.694 0.306 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.694 0.306 0.000
X50-X57 Overexertion, travel and privation
0.694 0.306 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.694 0.306 0.000
X30-X39 Exposure to forces of nature
0.694 0.306 0.000
X20-X29 Contact with venomous animals and plants
0.694 0.306 0.000
X10-X19 Contact with heat and hot substances
0.694 0.306 0.000
X00-X09 Exposure to smoke, fire and flames
0.694 0.306 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.694 0.306 0.000
W75-W84 Other accidental threats to breathing
0.694 0.306 0.000
W65-W74 Accidental drowning and submersion
0.694 0.306 0.000
W50-W64 Exposure to animate mechanical forces
0.694 0.306 0.000
V98-V99 Other and unspecified transport accidents
0.694 0.306 0.000
V95-V97 Air and space transport accidents
0.694 0.306 0.000
V90-V94 Water transport accidents
0.694 0.306 0.000
V80-V89 Other land transport accidents
0.694 0.306 0.000
V70-V79 Bus occupant injured in transport accident
0.694 0.306 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.694 0.306 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.694 0.306 0.000
V40-V49 Car occupant injured in transport accident
0.694 0.306 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.694 0.306 0.000
V01-V09 Pedestrian injured in transport accident
0.694 0.306 0.000
M54.8 Other dorsalgia
0.693 0.307 0.000
M54.4 Lumbago with sciatica
0.693 0.307 0.000
M54.0 Panniculitis affecting regions of neck and back
0.693 0.307 0.000
M25 Other joint disorders, not elsewhere classified
0.693 0.307 0.000
M54.12 Radiculopathy (Cervical region)
0.693 0.307 0.000
M75.8 Other shoulder lesions
0.692 0.308 0.000
M75.9 Shoulder lesion, unspecified
0.692 0.308 0.000
M75.2 Bicipital tendinitis
0.692 0.308 0.000
I73 Other peripheral vascular diseases
0.691 0.309 0.000
E85 Amyloidosis
0.691 0.309 0.000
E84 Cystic fibrosis
0.691 0.309 0.000
E79 Disorders of purine and pyrimidine metabolism
0.691 0.309 0.000
E77 Disorders of glycoprotein metabolism
0.691 0.309 0.000
E76 Disorders of glycosaminoglycan metabolism
0.691 0.309 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.691 0.309 0.000
E74 Other disorders of carbohydrate metabolism
0.691 0.309 0.000
E73 Lactose intolerance
0.691 0.309 0.000
E72 Other disorders of amino-acid metabolism
0.691 0.309 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.691 0.309 0.000
E70 Disorders of aromatic amino-acid metabolism
0.691 0.309 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.691 0.309 0.000
N36.8 Other specified disorders of urethra
0.690 0.310 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.690 0.310 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.690 0.310 0.000
C09 Malignant neoplasm of tonsil
0.689 0.311 0.000
D55-D59 Haemolytic anaemias
0.689 0.311 0.000
N35 Urethral stricture
0.688 0.312 0.000
C18.4 Transverse colon
0.687 0.313 0.000
M89 Other disorders of bone
0.686 0.314 0.000
M47.8 Other spondylosis
0.686 0.314 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.684 0.315 0.000
N15 Other renal tubulo-interstitial diseases
0.684 0.315 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.684 0.315 0.000
N11 Chronic tubulo-interstitial nephritis
0.684 0.315 0.000
N32 Other disorders of bladder
0.683 0.317 0.000
C18.2 Ascending colon
0.683 0.317 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.683 0.317 0.000
I10-I15 Hypertensive diseases
0.682 0.318 0.000
I70 Atherosclerosis
0.682 0.318 0.000
N39.0 Urinary tract infection, site not specified
0.682 0.318 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.681 0.319 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.681 0.319 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.681 0.319 0.000
E87.4 Mixed disorder of acid-base balance
0.681 0.319 0.000
N20.0 Calculus of kidney
0.680 0.320 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.678 0.322 0.000
N41 Inflammatory diseases of prostate
0.678 0.322 0.000
N25-N29 Other disorders of kidney and ureter
0.677 0.323 0.000
M54.22 Cervicalgia (Cervical region)
0.677 0.323 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.677 0.323 0.000
N76 Other inflammation of vagina and vulva
0.676 0.324 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.675 0.324 0.000
N17.8 Other acute renal failure
0.675 0.325 0.000
N17.2 Acute renal failure with medullary necrosis
0.675 0.325 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.675 0.325 0.000
N17.0 Acute renal failure with tubular necrosis
0.675 0.325 0.000
M86 Osteomyelitis
0.674 0.326 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.674 0.326 0.000
I69 Sequelae of cerebrovascular disease
0.674 0.326 0.000
C25.8 Overlapping lesion of pancreas
0.673 0.327 0.000
C25.7 Other parts of pancreas
0.673 0.327 0.000
C25.4 Endocrine pancreas
0.673 0.327 0.000
C25.3 Pancreatic duct
0.673 0.327 0.000
C25.2 Tail of pancreas
0.673 0.327 0.000
C25.1 Body of pancreas
0.673 0.327 0.000
I62 Other nontraumatic intracranial haemorrhage
0.673 0.327 0.000
S42.00 Fracture of clavicle (closed)
0.673 0.327 0.000
C16.0 Cardia
0.672 0.328 0.000
H73 Other disorders of tympanic membrane
0.672 0.328 0.000
I52 Other heart disorders in diseases classified elsewhere
0.671 0.329 0.000
I48 Atrial fibrillation and flutter
0.671 0.329 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.671 0.329 0.000
I41 Myocarditis in diseases classified elsewhere
0.671 0.329 0.000
I40 Acute myocarditis
0.671 0.329 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.671 0.329 0.000
I37 Pulmonary valve disorders
0.671 0.329 0.000
I36 Nonrheumatic tricuspid valve disorders
0.671 0.329 0.000
I32 Pericarditis in diseases classified elsewhere
0.671 0.329 0.000
S48 Traumatic amputation of shoulder and upper arm
0.671 0.329 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.671 0.329 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.671 0.329 0.000
S44 Injury of nerves at shoulder and upper arm level
0.671 0.329 0.000
S41 Open wound of shoulder and upper arm
0.671 0.329 0.000
S47 Crushing injury of shoulder and upper arm
0.671 0.329 0.000
M77 Other enthesopathies
0.670 0.330 0.000
M54.55 Low back pain (Thoracolumbar region)
0.669 0.331 0.000
M54.54 Low back pain-Thoracic
0.669 0.331 0.000
M54.53 Low back pain-Cervicothoracic
0.669 0.331 0.000
M54.52 Low back pain-Cervical
0.669 0.331 0.000
M54.51 Low back pain-Occipit-atl-axl
0.669 0.331 0.000
M54.50 Low back pain (Multiple sites in spine)
0.669 0.331 0.000
M24 Other specific joint derangements
0.669 0.331 0.000
N21.0 Calculus in bladder
0.666 0.333 0.000
C80 Malignant neoplasm without specification of site
0.665 0.335 0.000
J84 Other interstitial pulmonary diseases
0.665 0.335 0.000
S90-S99 Injuries to the ankle and foot
0.664 0.336 0.000
K11 Diseases of salivary glands
0.664 0.336 0.000
I35 Nonrheumatic aortic valve disorders
0.664 0.336 0.000
S30.1 Contusion of abdominal wall
0.664 0.336 0.000
N37 Urethral disorders in diseases classified elsewhere
0.663 0.337 0.000
N33 Bladder disorders in diseases classified elsewhere
0.663 0.337 0.000
M65 Synovitis and tenosynovitis
0.663 0.337 0.000
M21 Other acquired deformities of limbs
0.663 0.337 0.000
T66-T78 Other and unspecified effects of external causes
0.662 0.338 0.000
I67.9 Cerebrovascular disease, unspecified
0.662 0.338 0.000
I51 Complications and ill-defined descriptions of heart disease
0.661 0.338 0.000
I71.0 Dissection of aorta [any part]
0.660 0.340 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.660 0.340 0.000
H80-H83 Diseases of inner ear
0.659 0.341 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.658 0.342 0.000
M87 Osteonecrosis
0.658 0.342 0.000
W20-W49 Exposure to inanimate mechanical forces
0.658 0.342 0.000
M54.9 Dorsalgia, unspecified
0.658 0.342 0.000
D64 Other anaemias
0.658 0.342 0.000
N70 Salpingitis and oophoritis
0.657 0.343 0.000
M71.3 Other bursal cyst
0.657 0.343 0.000
S42.1 Fracture of scapula
0.656 0.344 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.656 0.344 0.000
E14 Unspecified diabetes mellitus
0.656 0.344 0.000
E83.4 Disorders of magnesium metabolism
0.655 0.345 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.655 0.345 0.000
Y52 Agents primarily affecting the cardiovascular system
0.654 0.346 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.654 0.346 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.654 0.346 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.654 0.346 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.654 0.346 0.000
I74.5 Embolism and thrombosis of iliac artery
0.652 0.348 0.000
C77.8 Lymph nodes of multiple regions
0.651 0.349 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.651 0.349 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.651 0.349 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.650 0.350 0.000
M72 Fibroblastic disorders
0.650 0.350 0.000
N42 Other disorders of prostate
0.649 0.350 0.000
I20-I25 Ischaemic heart diseases
0.649 0.351 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.649 0.351 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.649 0.351 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.648 0.351 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.648 0.352 0.000
C60 Malignant neoplasm of penis
0.648 0.352 0.000
C77.5 Intrapelvic lymph nodes
0.648 0.352 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.648 0.352 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.648 0.352 0.000
S37 Injury of urinary and pelvic organs
0.648 0.352 0.000
S36 Injury of intra-abdominal organs
0.648 0.352 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.648 0.352 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.648 0.352 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.648 0.352 0.000
S31 Open wound of abdomen, lower back and pelvis
0.648 0.352 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.648 0.352 0.000
W00-W19 Falls
0.648 0.352 0.000
E20-E35 Disorders of other endocrine glands
0.646 0.353 0.000
S42.40 Fracture of lower end of humerus (closed)
0.646 0.354 0.000
E88 Other metabolic disorders
0.646 0.354 0.000
S51 Open wound of forearm
0.644 0.356 0.000
I33 Acute and subacute endocarditis
0.644 0.356 0.000
M47.86 Other spondylosis (Lumbar region)
0.644 0.356 0.000
S00.8 Superficial injury of other parts of head
0.644 0.356 0.000
D24 Benign neoplasm of breast
0.644 0.356 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.643 0.357 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.643 0.357 0.000
I42.8 Other cardiomyopathies
0.642 0.358 0.000
M41 Scoliosis
0.642 0.358 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.641 0.359 0.000
S20-S29 Injuries to the thorax
0.640 0.360 0.000
E83.5 Disorders of calcium metabolism
0.640 0.360 0.000
S05 Injury of eye and orbit
0.640 0.360 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.638 0.362 0.000
Y57 Other and unspecified drugs and medicaments
0.638 0.362 0.000
I09 Other rheumatic heart diseases
0.638 0.362 0.000
I06 Rheumatic aortic valve diseases
0.638 0.362 0.000
I05 Rheumatic mitral valve diseases
0.638 0.362 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.637 0.363 0.000
I74.8 Embolism and thrombosis of other arteries
0.637 0.363 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.637 0.363 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.637 0.363 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.637 0.363 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.637 0.363 0.000
C32 Malignant neoplasm of larynx
0.637 0.363 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.637 0.363 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.637 0.363 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.636 0.364 0.000
S00.0 Superficial injury of scalp
0.635 0.365 0.000
S43.0 Dislocation of shoulder joint
0.635 0.365 0.000
K55-K64 Other diseases of intestines
0.634 0.366 0.000
C77.4 Inguinal and lower limb lymph nodes
0.632 0.368 0.000
N03.9 Unspecified
0.632 0.368 0.000
N13.8 Other obstructive and reflux uropathy
0.632 0.368 0.000
D22 Melanocytic naevi
0.632 0.368 0.000
J43.8 Other emphysema
0.631 0.369 0.000
J43.2 Centrilobular emphysema
0.631 0.369 0.000
J43.1 Panlobular emphysema
0.631 0.369 0.000
J43.0 MacLeod's syndrome
0.631 0.369 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.631 0.369 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.630 0.370 0.000
J46 Status asthmaticus
0.629 0.370 0.000
C62 Malignant neoplasm of testis
0.629 0.371 0.000
J92.0 Pleural plaque with presence of asbestos
0.629 0.371 0.000
T86 Failure and rejection of transplanted organs and tissues
0.628 0.372 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.628 0.372 0.000
D17 Benign lipomatous neoplasm
0.628 0.372 0.000
E87.7 Fluid overload
0.627 0.373 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.627 0.373 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.627 0.373 0.000
Y98 Lifestyle-related condition
0.627 0.373 0.000
Y97 Environmental-pollution-related condition
0.627 0.373 0.000
Y96 Work-related condition
0.627 0.373 0.000
K90-K93 Other diseases of the digestive system
0.627 0.373 0.000
C18.8 Overlapping lesion of colon
0.626 0.373 0.000
C18.6 Descending colon
0.626 0.373 0.000
C18.5 Splenic flexure
0.626 0.373 0.000
C18.3 Hepatic flexure
0.626 0.373 0.000
C18.1 Appendix
0.626 0.373 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.626 0.374 0.000
I08.0 Disorders of both mitral and aortic valves
0.625 0.375 0.000
M88 Paget's disease of bone [osteitis deformans]
0.625 0.375 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.625 0.375 0.000
D84 Other immunodeficiencies
0.624 0.375 0.000
D83 Common variable immunodeficiency
0.624 0.375 0.000
D82 Immunodeficiency associated with other major defects
0.624 0.375 0.000
D81 Combined immunodeficiencies
0.624 0.375 0.000
D80 Immunodeficiency with predominantly antibody defects
0.624 0.375 0.000
S06 Intracranial injury
0.624 0.376 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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