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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74835065
log Bayes Factor = 17.9198
Chromosome 4   position 34,894,970  (GRCh37) Explore rs74835065 on Ensembl!
Variant rs74835065 is part of Cluster X0020

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
A30-A49 Other bacterial diseases
0.998 0.002 0.000
Chapter X Diseases of the respiratory system
0.997 0.003 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.996 0.004 0.000
A41 Other septicaemia
0.994 0.006 0.000
C79 Secondary malignant neoplasm of other sites
0.992 0.008 0.000
C78.0 Secondary malignant neoplasm of lung
0.989 0.011 0.000
J09-J18 Influenza and pneumonia
0.989 0.011 0.000
Chapter XIV Diseases of the genitourinary system
0.988 0.012 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.987 0.013 0.000
N17-N19 Renal failure
0.985 0.015 0.000
A41.9 Septicaemia, unspecified
0.985 0.015 0.000
Chapter XXI Factors influencing health status and contact with health services
0.984 0.016 0.000
N17 Acute renal failure
0.981 0.019 0.000
B95-B98 Bacterial, viral and other infectious agents
0.979 0.021 0.000
N17.9 Acute renal failure, unspecified
0.978 0.022 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.978 0.022 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.976 0.024 0.000
Chapter VI Diseases of the nervous system
0.969 0.031 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.968 0.032 0.000
J18 Pneumonia, organism unspecified
0.967 0.033 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.964 0.036 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.952 0.048 0.000
D00-D09 In situ neoplasms
0.951 0.049 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.950 0.050 0.000
I71 Aortic aneurysm and dissection
0.947 0.053 0.000
J18.9 Pneumonia, unspecified
0.945 0.055 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.942 0.058 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.942 0.058 0.000
I44 Atrioventricular and left bundle-branch block
0.941 0.059 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.932 0.068 0.000
Chapter XX External causes of morbidity and mortality
0.928 0.072 0.000
I50 Heart failure
0.924 0.076 0.000
J90-J94 Other diseases of pleura
0.916 0.084 0.000
Z50 Care involving use of rehabilitation procedures
0.915 0.085 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.915 0.085 0.000
C78.7 Secondary malignant neoplasm of liver
0.912 0.088 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.911 0.089 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.908 0.092 0.000
I27 Other pulmonary heart diseases
0.906 0.094 0.000
I60-I69 Cerebrovascular diseases
0.902 0.098 0.000
J30-J39 Other diseases of upper respiratory tract
0.902 0.098 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.901 0.099 0.000
I95 Hypotension
0.900 0.100 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.899 0.101 0.000
D05 Carcinoma in situ of breast
0.899 0.101 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.896 0.104 0.000
A49 Bacterial infection of unspecified site
0.893 0.107 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.888 0.112 0.000
I42 Cardiomyopathy
0.884 0.116 0.000
I50.9 Heart failure, unspecified
0.877 0.123 0.000
N00-N08 Glomerular diseases
0.877 0.123 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.877 0.123 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.875 0.125 0.000
I49 Other cardiac arrhythmias
0.875 0.125 0.000
I63 Cerebral infarction
0.872 0.128 0.000
I44.0 Atrioventricular block, first degree
0.869 0.131 0.000
I26 Pulmonary embolism
0.868 0.132 0.000
J00-J06 Acute upper respiratory infections
0.861 0.139 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.860 0.140 0.000
N10-N16 Renal tubulo-interstitial diseases
0.859 0.141 0.000
Z40 Prophylactic surgery
0.856 0.144 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.856 0.144 0.000
Z49 Care involving dialysis
0.853 0.147 0.000
S40-S49 Injuries to the shoulder and upper arm
0.851 0.149 0.000
I34 Nonrheumatic mitral valve disorders
0.850 0.150 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.847 0.153 0.000
J18.1 Lobar pneumonia, unspecified
0.845 0.155 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.842 0.158 0.000
G30-G32 Other degenerative diseases of the nervous system
0.841 0.159 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.837 0.163 0.000
M65-M68 Disorders of synovium and tendon
0.837 0.163 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.837 0.163 0.000
I63.9 Cerebral infarction, unspecified
0.833 0.167 0.000
Z95.2 Presence of prosthetic heart valve
0.832 0.168 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.831 0.169 0.000
M80-M85 Disorders of bone density and structure
0.831 0.169 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.829 0.171 0.000
D05.1 Intraductal carcinoma in situ
0.827 0.172 0.000
M05-M14 Inflammatory polyarthropathies
0.826 0.174 0.000
J10 Influenza due to identified influenza virus
0.826 0.174 0.000
I95.1 Orthostatic hypotension
0.825 0.175 0.000
I20-I25 Ischaemic heart diseases
0.822 0.178 0.000
N18 Chronic renal failure
0.821 0.179 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.820 0.180 0.000
Z60 Problems related to social environment
0.820 0.180 0.000
C77.2 Intra-abdominal lymph nodes
0.820 0.180 0.000
G56 Mononeuropathies of upper limb
0.816 0.184 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.816 0.184 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.816 0.184 0.000
C77.0 Lymph nodes of head, face and neck
0.816 0.184 0.000
I31 Other diseases of pericardium
0.815 0.185 0.000
I05-I09 Chronic rheumatic heart diseases
0.815 0.185 0.000
Z93 Artificial opening status
0.814 0.186 0.000
A41.8 Other specified septicaemia
0.813 0.187 0.000
C15-C26 Malignant neoplasms of digestive organs
0.813 0.187 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.811 0.189 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.811 0.189 0.000
I78 Diseases of capillaries
0.811 0.189 0.000
M13 Other arthritis
0.808 0.192 0.000
J93 Pneumothorax
0.808 0.192 0.000
S80-S89 Injuries to the knee and lower leg
0.807 0.193 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.806 0.194 0.000
I44.1 Atrioventricular block, second degree
0.805 0.195 0.000
Z50.1 Other physical therapy
0.804 0.196 0.000
C79.2 Secondary malignant neoplasm of skin
0.804 0.196 0.000
Z51 Other medical care
0.803 0.197 0.000
I27.2 Other secondary pulmonary hypertension
0.802 0.198 0.000
Z95.0 Presence of cardiac pacemaker
0.802 0.198 0.000
A46 Erysipelas
0.800 0.200 0.000
B35-B49 Mycoses
0.799 0.201 0.000
J35 Chronic diseases of tonsils and adenoids
0.797 0.203 0.000
M13.9 Arthritis, unspecified
0.796 0.204 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.795 0.205 0.000
C80 Malignant neoplasm without specification of site
0.794 0.206 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.792 0.208 0.000
C01 Malignant neoplasm of base of tongue
0.791 0.209 0.000
J34 Other disorders of nose and nasal sinuses
0.784 0.216 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.784 0.216 0.000
D05.0 Lobular carcinoma in situ
0.782 0.218 0.000
I27.0 Primary pulmonary hypertension
0.782 0.218 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.781 0.219 0.000
A80-A89 Viral infections of the central nervous system
0.781 0.219 0.000
Z60.2 Living alone
0.780 0.220 0.000
I51 Complications and ill-defined descriptions of heart disease
0.779 0.221 0.000
Z92 Personal history of medical treatment
0.778 0.222 0.000
Z42 Follow-up care involving plastic surgery
0.778 0.222 0.000
M65 Synovitis and tenosynovitis
0.778 0.222 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.778 0.222 0.000
S50-S59 Injuries to the elbow and forearm
0.777 0.223 0.000
D04 Carcinoma in situ of skin
0.776 0.224 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.776 0.224 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.773 0.227 0.000
I72 Other aneurysm
0.772 0.228 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.772 0.228 0.000
G90-G99 Other disorders of the nervous system
0.771 0.229 0.000
Z45 Adjustment and management of implanted device
0.770 0.230 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.769 0.230 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.769 0.231 0.000
N03 Chronic nephritic syndrome
0.766 0.234 0.000
S90-S99 Injuries to the ankle and foot
0.765 0.235 0.000
J90 Pleural effusion, not elsewhere classified
0.764 0.236 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.763 0.237 0.000
G56.0 Carpal tunnel syndrome
0.762 0.238 0.000
D70 Agranulocytosis
0.761 0.239 0.000
D46 Myelodysplastic syndromes
0.760 0.240 0.000
Z52 Donors of organs and tissues
0.759 0.241 0.000
Z51.1 Chemotherapy session for neoplasm
0.759 0.241 0.000
A49.8 Other bacterial infections of unspecified site
0.759 0.241 0.000
G30 Alzheimer's disease
0.759 0.241 0.000
I73 Other peripheral vascular diseases
0.758 0.242 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.757 0.243 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.756 0.244 0.000
I70 Atherosclerosis
0.755 0.245 0.000
I36 Nonrheumatic tricuspid valve disorders
0.755 0.245 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.755 0.245 0.000
D03 Melanoma in situ
0.755 0.245 0.000
G50 Disorders of trigeminal nerve
0.754 0.246 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.753 0.247 0.000
C77.4 Inguinal and lower limb lymph nodes
0.749 0.251 0.000
D10-D36 Benign neoplasms
0.749 0.251 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.748 0.252 0.000
I49.5 Sick sinus syndrome
0.748 0.252 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.748 0.252 0.000
Chapter XXII Codes for special purposes
0.748 0.252 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.748 0.252 0.000
I33 Acute and subacute endocarditis
0.747 0.253 0.000
I45 Other conduction disorders
0.746 0.253 0.000
W20-W49 Exposure to inanimate mechanical forces
0.746 0.254 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.745 0.255 0.000
Z50.8 Care involving use of rehabilitation procedures
0.745 0.255 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.744 0.256 0.000
T79-T79 Certain early complications of trauma
0.743 0.257 0.000
Z49.1 Extracorporeal dialysis
0.740 0.260 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.739 0.261 0.000
C09 Malignant neoplasm of tonsil
0.738 0.262 0.000
I35 Nonrheumatic aortic valve disorders
0.737 0.263 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.737 0.263 0.000
T66-T78 Other and unspecified effects of external causes
0.736 0.264 0.000
Z46 Fitting and adjustment of other devices
0.736 0.264 0.000
I22 Subsequent myocardial infarction
0.736 0.264 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.735 0.265 0.000
G62 Other polyneuropathies
0.734 0.266 0.000
C50-C50 Malignant neoplasm of breast
0.734 0.266 0.000
J93.9 Pneumothorax, unspecified
0.733 0.267 0.000
I30 Acute pericarditis
0.733 0.267 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.732 0.268 0.000
M65.3 Trigger finger
0.732 0.268 0.000
I62 Other nontraumatic intracranial haemorrhage
0.731 0.269 0.000
G70-G73 Diseases of myoneural junction and muscle
0.730 0.270 0.000
I95.2 Hypotension due to drugs
0.730 0.270 0.000
D23 Other benign neoplasms of skin
0.730 0.270 0.000
J03 Acute tonsillitis
0.728 0.271 0.000
J30 Vasomotor and allergic rhinitis
0.727 0.273 0.000
C77.8 Lymph nodes of multiple regions
0.726 0.274 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.726 0.274 0.000
I49.1 Atrial premature depolarisation
0.726 0.274 0.000
A49.0 Staphylococcal infection, unspecified
0.725 0.275 0.000
Z50.5 Speech therapy
0.724 0.276 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.723 0.276 0.000
J39 Other diseases of upper respiratory tract
0.722 0.278 0.000
J36 Peritonsillar abscess
0.722 0.278 0.000
S20-S29 Injuries to the thorax
0.722 0.278 0.000
J91 Pleural effusion in conditions classified elsewhere
0.721 0.279 0.000
I25 Chronic ischaemic heart disease
0.719 0.281 0.000
T90 Sequelae of injuries of head
0.719 0.281 0.000
B25-B34 Other viral diseases
0.719 0.281 0.000
I42.6 Alcoholic cardiomyopathy
0.719 0.281 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.717 0.283 0.000
S00-S09 Injuries to the head
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
A48 Other bacterial diseases, not elsewhere classified
0.716 0.284 0.000
A44 Bartonellosis
0.716 0.284 0.000
A43 Nocardiosis
0.716 0.284 0.000
A42 Actinomycosis
0.716 0.284 0.000
A40 Streptococcal septicaemia
0.716 0.284 0.000
A39 Meningococcal infection
0.716 0.284 0.000
A37 Whooping cough
0.716 0.284 0.000
A36 Diphtheria
0.716 0.284 0.000
A32 Listeriosis
0.716 0.284 0.000
A31 Infection due to other mycobacteria
0.716 0.284 0.000
A30 Leprosy [Hansen's disease]
0.716 0.284 0.000
A38 Scarlet fever
0.716 0.284 0.000
A35 Other tetanus
0.716 0.284 0.000
A34 Obstetrical tetanus
0.716 0.284 0.000
A33 Tetanus neonatorum
0.716 0.284 0.000
I95.9 Hypotension, unspecified
0.715 0.285 0.000
Z95.4 Presence of other heart-valve replacement
0.715 0.285 0.000
N99-N99 Other disorders of the genitourinary system
0.715 0.285 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.714 0.286 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.714 0.286 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.714 0.286 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.714 0.286 0.000
J01 Acute sinusitis
0.714 0.286 0.000
Y84.2 Radiological procedure and radiotherapy
0.713 0.287 0.000
A41.4 Septicaemia due to anaerobes
0.713 0.287 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.713 0.287 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.713 0.287 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.713 0.287 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.713 0.287 0.000
C79.6 Secondary malignant neoplasm of ovary
0.711 0.288 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.711 0.288 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.711 0.288 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.711 0.288 0.000
I34.0 Mitral (valve) insufficiency
0.711 0.289 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.711 0.289 0.000
N19 Unspecified renal failure
0.710 0.290 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.710 0.290 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.709 0.291 0.000
C77.3 Axillary and upper limb lymph nodes
0.709 0.291 0.000
I42.9 Cardiomyopathy, unspecified
0.709 0.291 0.000
J17 Pneumonia in diseases classified elsewhere
0.709 0.291 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.709 0.291 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.709 0.291 0.000
J12 Viral pneumonia, not elsewhere classified
0.709 0.291 0.000
J11 Influenza, virus not identified
0.709 0.291 0.000
J14 Pneumonia due to Haemophilus influenzae
0.709 0.291 0.000
J09 Influenza due to certain identified influenza virus
0.709 0.291 0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.709 0.291 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.708 0.292 0.000
C78.2 Secondary malignant neoplasm of pleura
0.708 0.292 0.000
T33-T35 Frostbite
0.708 0.292 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.708 0.292 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.708 0.292 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.708 0.292 0.000
T00-T07 Injuries involving multiple body regions
0.708 0.292 0.000
S10-S19 Injuries to the neck
0.708 0.292 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.707 0.292 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.707 0.292 0.000
D45 Polycythaemia vera
0.707 0.293 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.707 0.293 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.706 0.294 0.000
T81 Complications of procedures, not elsewhere classified
0.706 0.294 0.000
G57 Mononeuropathies of lower limb
0.703 0.297 0.000
N17.8 Other acute renal failure
0.703 0.297 0.000
N17.2 Acute renal failure with medullary necrosis
0.703 0.297 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.703 0.297 0.000
N17.0 Acute renal failure with tubular necrosis
0.703 0.297 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.701 0.299 0.000
B15-B19 Viral hepatitis
0.701 0.299 0.000
Z54 Convalescence
0.700 0.300 0.000
Z44 Fitting and adjustment of external prosthetic device
0.700 0.300 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.699 0.301 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.698 0.301 0.000
M65.34 Trigger finger-Hand
0.699 0.301 0.000
S60-S69 Injuries to the wrist and hand
0.697 0.303 0.000
Z50.2 Alcohol rehabilitation
0.696 0.304 0.000
X60-X84 Intentional self-harm
0.696 0.304 0.000
N10 Acute tubulo-interstitial nephritis
0.696 0.304 0.000
I42.8 Other cardiomyopathies
0.695 0.305 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.695 0.305 0.000
I49.8 Other specified cardiac arrhythmias
0.695 0.305 0.000
Z94 Transplanted organ and tissue status
0.695 0.305 0.000
I50.0 Congestive heart failure
0.695 0.305 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.694 0.306 0.000
S70-S79 Injuries to the hip and thigh
0.694 0.306 0.000
I28 Other diseases of pulmonary vessels
0.694 0.306 0.000
J18.8 Other pneumonia, organism unspecified
0.693 0.306 0.000
J18.2 Hypostatic pneumonia, unspecified
0.693 0.306 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.693 0.306 0.000
M85 Other disorders of bone density and structure
0.693 0.307 0.000
Z95.3 Presence of xenogenic heart valve
0.693 0.307 0.000
I78.1 Naevus, nonneoplastic
0.691 0.309 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.691 0.309 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.691 0.309 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.691 0.309 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.691 0.309 0.000
T86 Failure and rejection of transplanted organs and tissues
0.689 0.311 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.689 0.311 0.000
L60-L75 Disorders of skin appendages
0.688 0.312 0.000
N18.0 End-stage renal disease
0.688 0.312 0.000
A00-A09 Intestinal infectious diseases
0.688 0.312 0.000
I61 Intracerebral haemorrhage
0.688 0.312 0.000
N03.9 Unspecified
0.687 0.313 0.000
Z41 Procedures for purposes other than remedying health state
0.686 0.313 0.000
N02 Recurrent and persistent haematuria
0.686 0.314 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.684 0.316 0.000
J35.0 Chronic tonsillitis
0.683 0.317 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.683 0.317 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.683 0.317 0.000
G58 Other mononeuropathies
0.683 0.317 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.683 0.317 0.000
I51.9 Heart disease, unspecified
0.683 0.317 0.000
I44.7 Left bundle-branch block, unspecified
0.682 0.318 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.682 0.318 0.000
I99 Other and unspecified disorders of circulatory system
0.682 0.318 0.000
N11 Chronic tubulo-interstitial nephritis
0.682 0.318 0.000
D09 Carcinoma in situ of other and unspecified sites
0.682 0.318 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.682 0.318 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.682 0.318 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.682 0.318 0.000
Chapter V Mental and behavioural disorders
0.682 0.318 0.000
S31 Open wound of abdomen, lower back and pelvis
0.682 0.318 0.000
I63.8 Other cerebral infarction
0.682 0.318 0.000
A49.9 Bacterial infection, unspecified
0.681 0.319 0.000
M86-M90 Other osteopathies
0.680 0.320 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.679 0.321 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.679 0.321 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.679 0.321 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.679 0.321 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.679 0.321 0.000
I71.0 Dissection of aorta [any part]
0.679 0.321 0.000
I27.9 Pulmonary heart disease, unspecified
0.678 0.321 0.000
Z93.3 Colostomy status
0.678 0.322 0.000
C25 Malignant neoplasm of pancreas
0.677 0.323 0.000
D50-D53 Nutritional anaemias
0.676 0.324 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.675 0.325 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.675 0.325 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.675 0.325 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.675 0.325 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.675 0.325 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.675 0.325 0.000
I44.6 Other and unspecified fascicular block
0.675 0.325 0.000
I44.5 Left posterior fascicular block
0.675 0.325 0.000
I44.4 Left anterior fascicular block
0.675 0.325 0.000
I44.3 Other and unspecified atrioventricular block
0.675 0.325 0.000
M84 Disorders of continuity of bone
0.675 0.325 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.674 0.326 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.674 0.326 0.000
M45-M49 Spondylopathies
0.673 0.327 0.000
N30-N39 Other diseases of urinary system
0.673 0.327 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.672 0.328 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.672 0.328 0.000
Z93.6 Other artificial openings of urinary tract status
0.671 0.329 0.000
M91-M94 Chondropathies
0.670 0.329 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.670 0.330 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.667 0.333 0.000
N18.8 Other chronic renal failure
0.667 0.333 0.000
D23.1 Skin of eyelid, including canthus
0.667 0.333 0.000
I34.1 Mitral (valve) prolapse
0.666 0.334 0.000
I49.3 Ventricular premature depolarisation
0.666 0.334 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.665 0.334 0.000
Y35-Y36 Legal intervention and operations of war
0.665 0.334 0.000
Y10-Y34 Event of undetermined intent
0.665 0.334 0.000
Y00-Y09 Assault
0.665 0.334 0.000
X85-X99 Assault
0.665 0.334 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.665 0.334 0.000
X50-X57 Overexertion, travel and privation
0.665 0.334 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.665 0.334 0.000
X30-X39 Exposure to forces of nature
0.665 0.334 0.000
X20-X29 Contact with venomous animals and plants
0.665 0.334 0.000
X10-X19 Contact with heat and hot substances
0.665 0.334 0.000
X00-X09 Exposure to smoke, fire and flames
0.665 0.334 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.665 0.334 0.000
W75-W84 Other accidental threats to breathing
0.665 0.334 0.000
W65-W74 Accidental drowning and submersion
0.665 0.334 0.000
W50-W64 Exposure to animate mechanical forces
0.665 0.334 0.000
V98-V99 Other and unspecified transport accidents
0.665 0.334 0.000
V95-V97 Air and space transport accidents
0.665 0.334 0.000
V90-V94 Water transport accidents
0.665 0.334 0.000
V80-V89 Other land transport accidents
0.665 0.334 0.000
V70-V79 Bus occupant injured in transport accident
0.665 0.334 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.665 0.334 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.665 0.334 0.000
V40-V49 Car occupant injured in transport accident
0.665 0.334 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.665 0.334 0.000
V01-V09 Pedestrian injured in transport accident
0.665 0.334 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.665 0.335 0.000
N04 Nephrotic syndrome
0.664 0.335 0.000
Z49.0 Preparatory care for dialysis
0.664 0.336 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.662 0.338 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.662 0.338 0.000
Z29 Need for other prophylactic measures
0.661 0.339 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.660 0.340 0.000
E10-E14 Diabetes mellitus
0.660 0.340 0.000
I60 Subarachnoid haemorrhage
0.660 0.340 0.000
I38 Endocarditis, valve unspecified
0.659 0.341 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.659 0.341 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.659 0.341 0.000
S50 Superficial injury of forearm
0.659 0.341 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.659 0.341 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.658 0.342 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.658 0.342 0.000
I05 Rheumatic mitral valve diseases
0.658 0.342 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.658 0.342 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.658 0.342 0.000
D41.4 Bladder
0.658 0.342 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.658 0.342 0.000
Z93.2 Ileostomy status
0.658 0.342 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.657 0.343 0.000
J35.8 Other chronic diseases of tonsils and adenoids
0.657 0.343 0.000
W00-W19 Falls
0.657 0.343 0.000
J94 Other pleural conditions
0.656 0.343 0.000
Z50.6 Orthoptic training
0.656 0.344 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.656 0.344 0.000
Z50.3 Drug rehabilitation
0.656 0.344 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.656 0.344 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.656 0.344 0.000
D24 Benign neoplasm of breast
0.654 0.346 0.000
M81 Osteoporosis without pathological fracture
0.653 0.347 0.000
I31.3 Pericardial effusion (noninflammatory)
0.653 0.347 0.000
G54 Nerve root and plexus disorders
0.653 0.347 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.653 0.347 0.000
G52 Disorders of other cranial nerves
0.653 0.347 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.652 0.348 0.000
D47.1 Chronic myeloproliferative disease
0.652 0.348 0.000
M60-M63 Disorders of muscles
0.651 0.349 0.000
M00-M03 Infectious arthropathies
0.651 0.349 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.651 0.349 0.000
J60-J70 Lung diseases due to external agents
0.650 0.349 0.000
Z93.1 Gastrostomy status
0.650 0.350 0.000
I27.8 Other specified pulmonary heart diseases
0.649 0.350 0.000
I27.1 Kyphoscoliotic heart disease
0.649 0.350 0.000
Y84.6 Urinary catheterisation
0.649 0.351 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.649 0.351 0.000
G30.9 Alzheimer's disease, unspecified
0.649 0.351 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.649 0.351 0.000
D23.7 Skin of lower limb, including hip
0.648 0.352 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.648 0.352 0.000
I07 Rheumatic tricuspid valve diseases
0.647 0.353 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.647 0.353 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.647 0.353 0.000
J37 Chronic laryngitis and laryngotracheitis
0.647 0.353 0.000
Z81 Family history of mental and behavioural disorders
0.647 0.353 0.000
I42.0 Dilated cardiomyopathy
0.646 0.354 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.646 0.354 0.000
C13 Malignant neoplasm of hypopharynx
0.646 0.354 0.000
C11 Malignant neoplasm of nasopharynx
0.646 0.354 0.000
C10 Malignant neoplasm of oropharynx
0.646 0.354 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.646 0.354 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.646 0.354 0.000
C05 Malignant neoplasm of palate
0.646 0.354 0.000
C04 Malignant neoplasm of floor of mouth
0.646 0.354 0.000
C03 Malignant neoplasm of gum
0.646 0.354 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.646 0.354 0.000
C00 Malignant neoplasm of lip
0.646 0.354 0.000
C12 Malignant neoplasm of pyriform sinus
0.646 0.354 0.000
C07 Malignant neoplasm of parotid gland
0.646 0.354 0.000
I95.8 Other hypotension
0.646 0.354 0.000
I95.0 Idiopathic hypotension
0.646 0.354 0.000
N18.5 Chronic kidney disease, stage 5
0.645 0.355 0.000
D05.7 Other carcinoma in situ of breast
0.645 0.355 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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