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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74961451
log Bayes Factor = 12.6422
Chromosome 1   position 59,608,141  (GRCh37) Explore rs74961451 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.995 0.005 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.993 0.007 0.000
E70-E90 Metabolic disorders
0.988 0.012 0.000
Chapter XX External causes of morbidity and mortality
0.984 0.016 0.000
E00-E07 Disorders of thyroid gland
0.981 0.019 0.000
E10-E14 Diabetes mellitus
0.980 0.020 0.000
Chapter XIV Diseases of the genitourinary system
0.977 0.023 0.000
N17-N19 Renal failure
0.966 0.034 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.966 0.034 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.963 0.037 0.000
Chapter VI Diseases of the nervous system
0.962 0.038 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.961 0.039 0.000
Z13 Special screening examination for other diseases and disorders
0.960 0.040 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.954 0.046 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.952 0.048 0.000
E14 Unspecified diabetes mellitus
0.947 0.053 0.000
Chapter VIII Diseases of the ear and mastoid process
0.945 0.055 0.000
C64-C68 Malignant neoplasms of urinary tract
0.937 0.063 0.000
N18 Chronic renal failure
0.934 0.066 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.934 0.066 0.000
T81 Complications of procedures, not elsewhere classified
0.930 0.070 0.000
C15-C26 Malignant neoplasms of digestive organs
0.930 0.070 0.000
T66-T78 Other and unspecified effects of external causes
0.926 0.074 0.000
E14.9 Without complications
0.925 0.075 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.924 0.076 0.000
Z01.8 Other specified special examinations
0.922 0.078 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.920 0.080 0.000
S60-S69 Injuries to the wrist and hand
0.915 0.085 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.914 0.086 0.000
E87.5 Hyperkalaemia
0.910 0.090 0.000
M05-M14 Inflammatory polyarthropathies
0.905 0.095 0.000
M70-M79 Other soft tissue disorders
0.904 0.096 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.902 0.098 0.000
C51-C58 Malignant neoplasms of female genital organs
0.901 0.098 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.900 0.100 0.000
G20-G26 Extrapyramidal and movement disorders
0.898 0.102 0.000
Chapter X Diseases of the respiratory system
0.894 0.106 0.000
M91-M94 Chondropathies
0.893 0.107 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.891 0.109 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.887 0.113 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.887 0.113 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.885 0.115 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.883 0.117 0.000
E10 Insulin-dependent diabetes mellitus
0.882 0.118 0.000
E65-E68 Obesity and other hyperalimentation
0.879 0.121 0.000
N19 Unspecified renal failure
0.877 0.123 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.876 0.124 0.000
J00-J06 Acute upper respiratory infections
0.872 0.128 0.000
T78 Adverse effects, not elsewhere classified
0.871 0.129 0.000
C15 Malignant neoplasm of oesophagus
0.871 0.129 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.870 0.130 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.869 0.131 0.000
H60-H62 Diseases of external ear
0.868 0.132 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.868 0.132 0.000
D00-D09 In situ neoplasms
0.867 0.133 0.000
E05.9 Thyrotoxicosis, unspecified
0.861 0.139 0.000
M20-M25 Other joint disorders
0.861 0.139 0.000
W00-W19 Falls
0.859 0.141 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.859 0.141 0.000
J09-J18 Influenza and pneumonia
0.858 0.142 0.000
G30-G32 Other degenerative diseases of the nervous system
0.853 0.147 0.000
J03 Acute tonsillitis
0.852 0.148 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.850 0.150 0.000
G90-G99 Other disorders of the nervous system
0.849 0.151 0.000
E87.6 Hypokalaemia
0.847 0.153 0.000
N18.5 Chronic kidney disease, stage 5
0.846 0.153 0.000
L03 Cellulitis
0.846 0.154 0.000
Z13.1 Special screening examination for diabetes mellitus
0.844 0.156 0.000
N00-N08 Glomerular diseases
0.844 0.156 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.842 0.157 0.000
E04 Other non-toxic goitre
0.839 0.161 0.000
M45-M49 Spondylopathies
0.838 0.162 0.000
J03.9 Acute tonsillitis, unspecified
0.838 0.162 0.000
Z22 Carrier of infectious disease
0.837 0.163 0.000
Z60 Problems related to social environment
0.835 0.165 0.000
C54 Malignant neoplasm of corpus uteri
0.834 0.166 0.000
Z12 Special screening examination for neoplasms
0.831 0.169 0.000
M25 Other joint disorders, not elsewhere classified
0.830 0.170 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.830 0.170 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.829 0.171 0.000
N73 Other female pelvic inflammatory diseases
0.828 0.172 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.826 0.174 0.000
M10 Gout
0.825 0.174 0.000
J18 Pneumonia, organism unspecified
0.825 0.175 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.823 0.177 0.000
T92 Sequelae of injuries of upper limb
0.822 0.178 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.820 0.180 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.815 0.185 0.000
G20 Parkinson's disease
0.812 0.188 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.811 0.189 0.000
N80 Endometriosis
0.811 0.189 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.811 0.189 0.000
E83 Disorders of mineral metabolism
0.810 0.190 0.000
Y44 Agents primarily affecting blood constituents
0.810 0.190 0.000
M25.5 Pain in joint
0.809 0.191 0.000
N75 Diseases of Bartholin's gland
0.809 0.191 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.808 0.192 0.000
E50-E64 Other nutritional deficiencies
0.807 0.193 0.000
E03 Other hypothyroidism
0.803 0.197 0.000
S10-S19 Injuries to the neck
0.802 0.198 0.000
Y45.0 Opioids and related analgesics
0.802 0.198 0.000
E87.3 Alkalosis
0.801 0.199 0.000
C67 Malignant neoplasm of bladder
0.799 0.201 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.798 0.202 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.797 0.203 0.000
Y52 Agents primarily affecting the cardiovascular system
0.796 0.204 0.000
Z58 Problems related to physical environment
0.795 0.205 0.000
M75 Shoulder lesions
0.795 0.205 0.000
M94 Other disorders of cartilage
0.795 0.205 0.000
E06 Thyroiditis
0.795 0.205 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.795 0.205 0.000
N80.0 Endometriosis of uterus
0.793 0.207 0.000
Z01.9 Special examination, unspecified
0.792 0.207 0.000
E66 Obesity
0.792 0.208 0.000
E20-E35 Disorders of other endocrine glands
0.790 0.210 0.000
J18.1 Lobar pneumonia, unspecified
0.790 0.210 0.000
N87 Dysplasia of cervix uteri
0.787 0.213 0.000
Y57 Other and unspecified drugs and medicaments
0.787 0.213 0.000
C54.1 Endometrium
0.786 0.214 0.000
S62 Fracture at wrist and hand level
0.785 0.215 0.000
Chapter XXII Codes for special purposes
0.785 0.215 0.000
D06 Carcinoma in situ of cervix uteri
0.784 0.216 0.000
Z39 Postpartum care and examination
0.782 0.218 0.000
M75.4 Impingement syndrome of shoulder
0.781 0.219 0.000
H90-H95 Other disorders of ear
0.781 0.219 0.000
S50-S59 Injuries to the elbow and forearm
0.781 0.219 0.000
C65 Malignant neoplasm of renal pelvis
0.777 0.223 0.000
T78.4 Allergy, unspecified
0.776 0.224 0.000
G30 Alzheimer's disease
0.776 0.224 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.776 0.224 0.000
G70-G73 Diseases of myoneural junction and muscle
0.775 0.225 0.000
N18.9 Chronic renal failure, unspecified
0.773 0.227 0.000
C25 Malignant neoplasm of pancreas
0.770 0.229 0.000
Z00.6 Examination for normal comparison and control in clinical research programme
0.770 0.230 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.770 0.230 0.000
M10.9 Gout, unspecified
0.769 0.231 0.000
L03.1 Cellulitis of other parts of limb
0.769 0.231 0.000
E10.9 Without complications
0.767 0.233 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.764 0.236 0.000
Z29 Need for other prophylactic measures
0.764 0.236 0.000
Z22.3 Carrier of other specified bacterial diseases
0.764 0.236 0.000
Z60.2 Living alone
0.764 0.236 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.763 0.237 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.760 0.240 0.000
C15.5 Lower third of oesophagus
0.760 0.240 0.000
Z13.9 Special screening examination, unspecified
0.759 0.241 0.000
N17 Acute renal failure
0.759 0.241 0.000
C34 Malignant neoplasm of bronchus and lung
0.758 0.242 0.000
M86-M90 Other osteopathies
0.758 0.242 0.000
M31 Other necrotising vasculopathies
0.757 0.243 0.000
N18.0 End-stage renal disease
0.756 0.244 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.756 0.244 0.000
H60 Otitis externa
0.756 0.244 0.000
G25 Other extrapyramidal and movement disorders
0.755 0.245 0.000
Z13.5 Special screening examination for eye and ear disorders
0.755 0.245 0.000
T79-T79 Certain early complications of trauma
0.755 0.245 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.755 0.245 0.000
L03.8 Cellulitis of other sites
0.754 0.246 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.753 0.247 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.752 0.248 0.000
N97 Female infertility
0.752 0.248 0.000
W19 Unspecified fall
0.752 0.248 0.000
M06 Other rheumatoid arthritis
0.751 0.249 0.000
S61 Open wound of wrist and hand
0.751 0.249 0.000
M25.57 Pain in joint (Ankle and foot)
0.750 0.250 0.000
H65-H75 Diseases of middle ear and mastoid
0.748 0.252 0.000
H61 Other disorders of external ear
0.748 0.252 0.000
E40-E46 Malnutrition
0.747 0.253 0.000
S20-S29 Injuries to the thorax
0.747 0.253 0.000
L40-L45 Papulosquamous disorders
0.747 0.253 0.000
E04.9 Non-toxic goitre, unspecified
0.744 0.256 0.000
Z01.6 Radiological examination, not elsewhere classified
0.744 0.256 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.744 0.256 0.000
E10.3 With ophthalmic complications
0.743 0.257 0.000
M80-M85 Disorders of bone density and structure
0.742 0.258 0.000
Z39.0 Care and examination immediately after delivery
0.742 0.258 0.000
E88 Other metabolic disorders
0.742 0.258 0.000
M48 Other spondylopathies
0.742 0.258 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.741 0.259 0.000
V40-V49 Car occupant injured in transport accident
0.740 0.259 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.739 0.261 0.000
D60-D64 Aplastic and other anaemias
0.738 0.262 0.000
N18.3 Chronic kidney disease, stage 3
0.737 0.263 0.000
S64 Injury of nerves at wrist and hand level
0.737 0.263 0.000
L50-L54 Urticaria and erythema
0.735 0.265 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.735 0.265 0.000
M05 Seropositive rheumatoid arthritis
0.735 0.265 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.734 0.265 0.000
E13 Other specified diabetes mellitus
0.734 0.266 0.000
E89.0 Postprocedural hypothyroidism
0.734 0.266 0.000
S90-S99 Injuries to the ankle and foot
0.733 0.267 0.000
M40-M43 Deforming dorsopathies
0.732 0.268 0.000
M50-M54 Other dorsopathies
0.732 0.268 0.000
C23 Malignant neoplasm of gallbladder
0.732 0.268 0.000
D47.2 Monoclonal gammopathy
0.729 0.271 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.729 0.271 0.000
L03.0 Cellulitis of finger and toe
0.729 0.271 0.000
N81 Female genital prolapse
0.729 0.271 0.000
M00-M03 Infectious arthropathies
0.729 0.271 0.000
G93 Other disorders of brain
0.728 0.272 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.727 0.273 0.000
E87.0 Hyperosmolality and hypernatraemia
0.726 0.274 0.000
C15.4 Middle third of oesophagus
0.726 0.274 0.000
N05 Unspecified nephritic syndrome
0.725 0.275 0.000
D06.9 Cervix, unspecified
0.724 0.276 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.724 0.276 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.723 0.277 0.000
M25.54 Pain in joint (Hand)
0.723 0.277 0.000
T87 Complications peculiar to reattachment and amputation
0.723 0.277 0.000
C17 Malignant neoplasm of small intestine
0.722 0.277 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.722 0.278 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.722 0.278 0.000
N73.6 Female pelvic peritoneal adhesions
0.722 0.278 0.000
Z01.4 Gynaecological examination (general)(routine)
0.722 0.278 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.721 0.279 0.000
X60-X84 Intentional self-harm
0.721 0.279 0.000
G30.9 Alzheimer's disease, unspecified
0.721 0.279 0.000
N75.1 Abscess of Bartholin's gland
0.720 0.280 0.000
N18.4 Chronic kidney disease, stage 4
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z00.0 General medical examination
0.717 0.283 0.000
N04 Nephrotic syndrome
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
T78.3 Angioneurotic oedema
0.714 0.286 0.000
Z10 Routine general health check-up of defined subpopulation
0.713 0.286 0.000
E61 Deficiency of other nutrient elements
0.713 0.287 0.000
M60-M63 Disorders of muscles
0.712 0.288 0.000
C15.9 Oesophagus, unspecified
0.711 0.289 0.000
C21 Malignant neoplasm of anus and anal canal
0.710 0.290 0.000
E85 Amyloidosis
0.709 0.291 0.000
E84 Cystic fibrosis
0.709 0.291 0.000
E79 Disorders of purine and pyrimidine metabolism
0.709 0.291 0.000
E77 Disorders of glycoprotein metabolism
0.709 0.291 0.000
E76 Disorders of glycosaminoglycan metabolism
0.709 0.291 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.709 0.291 0.000
E74 Other disorders of carbohydrate metabolism
0.709 0.291 0.000
E73 Lactose intolerance
0.709 0.291 0.000
E72 Other disorders of amino-acid metabolism
0.709 0.291 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.709 0.291 0.000
E70 Disorders of aromatic amino-acid metabolism
0.709 0.291 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.709 0.291 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.709 0.291 0.000
M93 Other osteochondropathies
0.709 0.291 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.709 0.291 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.708 0.292 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.707 0.293 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.705 0.295 0.000
Y35-Y36 Legal intervention and operations of war
0.705 0.295 0.000
Y10-Y34 Event of undetermined intent
0.705 0.295 0.000
Y00-Y09 Assault
0.705 0.295 0.000
X85-X99 Assault
0.705 0.295 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.705 0.295 0.000
X50-X57 Overexertion, travel and privation
0.705 0.295 0.000
X30-X39 Exposure to forces of nature
0.705 0.295 0.000
X20-X29 Contact with venomous animals and plants
0.705 0.295 0.000
X10-X19 Contact with heat and hot substances
0.705 0.295 0.000
X00-X09 Exposure to smoke, fire and flames
0.705 0.295 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.705 0.295 0.000
W75-W84 Other accidental threats to breathing
0.705 0.295 0.000
W65-W74 Accidental drowning and submersion
0.705 0.295 0.000
W50-W64 Exposure to animate mechanical forces
0.705 0.295 0.000
V98-V99 Other and unspecified transport accidents
0.705 0.295 0.000
V95-V97 Air and space transport accidents
0.705 0.295 0.000
V90-V94 Water transport accidents
0.705 0.295 0.000
V80-V89 Other land transport accidents
0.705 0.295 0.000
V70-V79 Bus occupant injured in transport accident
0.705 0.295 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.705 0.295 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.705 0.295 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.705 0.295 0.000
V01-V09 Pedestrian injured in transport accident
0.705 0.295 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.705 0.295 0.000
E07 Other disorders of thyroid
0.705 0.295 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.703 0.296 0.000
E00 Congenital iodine-deficiency syndrome
0.703 0.296 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.703 0.296 0.000
N99-N99 Other disorders of the genitourinary system
0.703 0.297 0.000
E12 Malnutrition-related diabetes mellitus
0.702 0.298 0.000
M77 Other enthesopathies
0.702 0.298 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.702 0.298 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.700 0.300 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.700 0.300 0.000
Z33 Pregnant state, incidental
0.699 0.301 0.000
S60 Superficial injury of wrist and hand
0.699 0.301 0.000
M94.2 Chondromalacia
0.699 0.301 0.000
Y44.2 Anticoagulants
0.699 0.301 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.698 0.302 0.000
T91 Sequelae of injuries of neck and trunk
0.697 0.303 0.000
C43 Malignant melanoma of skin
0.697 0.303 0.000
E10.2 With renal complications
0.697 0.303 0.000
S40-S49 Injuries to the shoulder and upper arm
0.696 0.304 0.000
T18 Foreign body in alimentary tract
0.696 0.304 0.000
Z58.1 Exposure to air pollution
0.696 0.304 0.000
M10.99 Gout, unspecified (Site unspecified)
0.694 0.306 0.000
N82 Fistulae involving female genital tract
0.694 0.306 0.000
N73.9 Female pelvic inflammatory disease, unspecified
0.694 0.306 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.693 0.307 0.000
Y59 Other and unspecified vaccines and biological substances
0.693 0.307 0.000
Y58 Bacterial vaccines
0.693 0.307 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.693 0.307 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.693 0.307 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.693 0.307 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.693 0.307 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.693 0.307 0.000
Y48 Anaesthetics and therapeutic gases
0.693 0.307 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.693 0.307 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.693 0.307 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.693 0.307 0.000
T81.9 Unspecified complication of procedure
0.693 0.307 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.692 0.308 0.000
D55-D59 Haemolytic anaemias
0.692 0.308 0.000
E66.8 Other obesity
0.691 0.309 0.000
E83.4 Disorders of magnesium metabolism
0.691 0.309 0.000
Z63 Other problems related to primary support group, including family circumstances
0.691 0.309 0.000
M65-M68 Disorders of synovium and tendon
0.691 0.309 0.000
J02 Acute pharyngitis
0.691 0.309 0.000
Z01.7 Laboratory examination
0.690 0.309 0.000
Z01.3 Examination of blood pressure
0.690 0.309 0.000
Z01.2 Dental examination
0.690 0.309 0.000
Z01.1 Examination of ears and hearing
0.690 0.309 0.000
Z01.0 Examination of eyes and vision
0.690 0.309 0.000
N95 Menopausal and other perimenopausal disorders
0.691 0.309 0.000
S67 Crushing injury of wrist and hand
0.690 0.309 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.690 0.310 0.000
M24 Other specific joint derangements
0.690 0.310 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.689 0.311 0.000
E87.4 Mixed disorder of acid-base balance
0.689 0.311 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.689 0.311 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.688 0.312 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.688 0.312 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.688 0.312 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.688 0.312 0.000
Z13.2 Special screening examination for nutritional disorders
0.688 0.312 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.688 0.312 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.687 0.313 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.687 0.313 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.685 0.315 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.685 0.315 0.000
C78.0 Secondary malignant neoplasm of lung
0.684 0.316 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.684 0.316 0.000
T86 Failure and rejection of transplanted organs and tissues
0.683 0.317 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.682 0.317 0.000
V10-V19 Pedal cyclist injured in transport accident
0.682 0.318 0.000
J18.0 Bronchopneumonia, unspecified
0.682 0.318 0.000
M25.8 Other specified joint disorders
0.681 0.319 0.000
T68 Hypothermia
0.681 0.319 0.000
W20-W49 Exposure to inanimate mechanical forces
0.681 0.319 0.000
N72 Inflammatory disease of cervix uteri
0.680 0.320 0.000
W13 Fall from, out of or through building or structure
0.680 0.320 0.000
E14.8 With unspecified complications
0.679 0.321 0.000
E14.7 With multiple complications
0.679 0.321 0.000
E14.6 With other specified complications
0.679 0.321 0.000
E14.5 With peripheral circulatory complications
0.679 0.321 0.000
E14.4 With neurological complications
0.679 0.321 0.000
E14.2 Withrenal complications
0.679 0.321 0.000
E14.1 With ketoacidosis
0.679 0.321 0.000
E14.0 With coma
0.679 0.321 0.000
N87.1 Moderate cervical dysplasia
0.679 0.321 0.000
D46 Myelodysplastic syndromes
0.679 0.321 0.000
G90 Disorders of autonomic nervous system
0.679 0.321 0.000
E89.3 Postprocedural hypopituitarism
0.678 0.322 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.678 0.322 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.678 0.322 0.000
T98 Sequelae of other and unspecified effects of external causes
0.678 0.322 0.000
Y45.2 Propionic acid derivatives
0.677 0.323 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.676 0.324 0.000
Z57 Occupational exposure to risk-factors
0.676 0.324 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.676 0.324 0.000
D05 Carcinoma in situ of breast
0.675 0.325 0.000
E14.3 With ophthalmic complications
0.674 0.326 0.000
M45 Ankylosing spondylitis
0.674 0.326 0.000
C71 Malignant neoplasm of brain
0.674 0.326 0.000
M31.6 Other giant cell arteritis
0.672 0.328 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.671 0.328 0.000
C66 Malignant neoplasm of ureter
0.671 0.328 0.000
T82.1 Mechanical complication of cardiac electronic device
0.671 0.329 0.000
E89.2 Postprocedural hypoparathyroidism
0.670 0.330 0.000
N81.8 Other female genital prolapse
0.670 0.330 0.000
N18.8 Other chronic renal failure
0.670 0.330 0.000
N18.1 Chronic kidney disease, stage 1
0.670 0.330 0.000
C01 Malignant neoplasm of base of tongue
0.669 0.330 0.000
Z65 Problems related to other psychosocial circumstances
0.669 0.331 0.000
Z64 Problems related to certain psychosocial circumstances
0.669 0.331 0.000
Z62 Other problems related to upbringing
0.669 0.331 0.000
Z61 Problems related to negative life events in childhood
0.669 0.331 0.000
Z59 Problems related to housing and economic circumstances
0.669 0.331 0.000
Z56 Problems related to employment and unemployment
0.669 0.331 0.000
Z55 Problems related to education and literacy
0.669 0.331 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.669 0.331 0.000
N97.9 Female infertility, unspecified
0.669 0.331 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.669 0.331 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.669 0.331 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.667 0.333 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.667 0.333 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.667 0.333 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.667 0.333 0.000
H90 Conductive and sensorineural hearing loss
0.667 0.333 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.667 0.333 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.666 0.334 0.000
S62.7 Multiple fractures of fingers
0.665 0.335 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.664 0.336 0.000
T75 Effects of other external causes
0.664 0.336 0.000
T74 Maltreatment syndromes
0.664 0.336 0.000
T73 Effects of other deprivation
0.664 0.336 0.000
T70 Effects of air pressure and water pressure
0.664 0.336 0.000
T69 Other effects of reduced temperature
0.664 0.336 0.000
T67 Effects of heat and light
0.664 0.336 0.000
T71 Asphyxiation
0.664 0.336 0.000
T66 Unspecified effects of radiation
0.664 0.336 0.000
H60.1 Cellulitis of external ear
0.663 0.337 0.000
M71 Other bursopathies
0.663 0.337 0.000
Z28 Immunisation not carried out
0.662 0.337 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.662 0.337 0.000
Z26 Need for immunisation against other single infectious diseases
0.662 0.337 0.000
Z25 Need for immunisation against other single viral diseases
0.662 0.337 0.000
Z24 Need for immunisation against certain single viral diseases
0.662 0.337 0.000
Z23 Need for immunisation against single bacterial diseases
0.662 0.337 0.000
Z20 Contact with and exposure to communicable diseases
0.662 0.337 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.662 0.337 0.000
M11 Other crystal arthropathies
0.662 0.338 0.000
E04.2 Non-toxic multinodular goitre
0.662 0.338 0.000
D03 Melanoma in situ
0.662 0.338 0.000
E06.3 Autoimmune thyroiditis
0.661 0.339 0.000
C67.2 Lateral wall of bladder
0.660 0.340 0.000
Y40 Systemic antibiotics
0.660 0.340 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.660 0.340 0.000
E05.8 Other thyrotoxicosis
0.660 0.340 0.000
E05.5 Thyroid crisis or storm
0.660 0.340 0.000
E05.4 Thyrotoxicosis factitia
0.660 0.340 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.660 0.340 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.660 0.340 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.660 0.340 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.659 0.341 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.658 0.342 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.658 0.342 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.658 0.342 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.658 0.342 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.658 0.342 0.000
C07 Malignant neoplasm of parotid gland
0.657 0.342 0.000
S68 Traumatic amputation of wrist and hand
0.656 0.343 0.000
S65 Injury of blood vessels at wrist and hand level
0.656 0.344 0.000
O80-O84 Delivery
0.656 0.344 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.655 0.345 0.000
E66.9 Obesity, unspecified
0.655 0.345 0.000
T93 Sequelae of injuries of lower limb
0.654 0.345 0.000
G24 Dystonia
0.654 0.346 0.000
E86 Volume depletion
0.653 0.347 0.000
V20-V29 Motorcycle rider injured in transport accident
0.652 0.348 0.000
N18.2 Chronic kidney disease, stage 2
0.652 0.348 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.651 0.349 0.000
Z35 Supervision of high-risk pregnancy
0.650 0.350 0.000
E87.7 Fluid overload
0.649 0.351 0.000
M14 Arthropathies in other diseases classified elsewhere
0.649 0.351 0.000
M12 Other specific arthropathies
0.649 0.351 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.649 0.351 0.000
M08 Juvenile arthritis
0.649 0.351 0.000
C43.5 Malignant melanoma of trunk
0.648 0.352 0.000
J11 Influenza, virus not identified
0.648 0.352 0.000
M48.0 Spinal stenosis
0.648 0.352 0.000
M76 Enthesopathies of lower limb, excluding foot
0.648 0.352 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.648 0.352 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.648 0.352 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.648 0.352 0.000
T95 Sequelae of burns, corrosions and frostbite
0.647 0.353 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.647 0.353 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.647 0.353 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.647 0.353 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.646 0.354 0.000
C51 Malignant neoplasm of vulva
0.646 0.354 0.000
C58 Malignant neoplasm of placenta
0.646 0.354 0.000
C52 Malignant neoplasm of vagina
0.646 0.354 0.000
E03.9 Hypothyroidism, unspecified
0.646 0.354 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.645 0.355 0.000
Y45.8 Other analgesics and antipyretics
0.645 0.355 0.000
Y45.5 4-Aminophenol derivatives
0.645 0.355 0.000
Y45.4 Antirheumatics
0.645 0.355 0.000
Y45.1 Salicylates
0.645 0.355 0.000
E61.1 Iron deficiency
0.645 0.355 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.645 0.355 0.000
G23 Other degenerative diseases of basal ganglia
0.643 0.356 0.000
G21 Secondary Parkinsonism
0.643 0.356 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.643 0.356 0.000
G22 Parkinsonism in diseases classified elsewhere
0.643 0.356 0.000
M06.9 Rheumatoid arthritis, unspecified
0.644 0.356 0.000
H80-H83 Diseases of inner ear
0.643 0.357 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.642 0.358 0.000
H61.2 Impacted cerumen
0.642 0.358 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.641 0.358 0.000
S69 Other and unspecified injuries of wrist and hand
0.640 0.359 0.000
H91 Other hearing loss
0.640 0.360 0.000
M92 Other juvenile osteochondrosis
0.640 0.360 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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