TreeWAS – Variant ID: rs74968339

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
I20-I25 Ischaemic heart diseases	0.999	0.001
E11 Non-insulin-dependent diabetes mellitus	0.996	0.004
Chapter II Neoplasms	0.996	0.004
I60-I69 Cerebrovascular diseases	0.994	0.006
E10 Insulin-dependent diabetes mellitus	0.988	0.012
I20 Angina pectoris	0.986	0.014
Chapter XX External causes of morbidity and mortality	0.984	0.016
C15-C26 Malignant neoplasms of digestive organs	0.983	0.017
S60-S69 Injuries to the wrist and hand	0.977	0.023
Chapter XI Diseases of the digestive system	0.977	0.023
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.976	0.024
I20.0 Unstable angina	0.976	0.024
Chapter I Certain infectious and parasitic diseases	0.976	0.024
K70-K77 Diseases of liver	0.974	0.026
E10.9 Without complications	0.967	0.033
K70 Alcoholic liver disease	0.960	0.040
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.958	0.042
B95-B98 Bacterial, viral and other infectious agents	0.957	0.043
C25 Malignant neoplasm of pancreas	0.957	0.043
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.956	0.044
I25 Chronic ischaemic heart disease	0.955	0.045
Chapter XV Pregnancy, childbirth and the puerperium	0.950	0.050
S20-S29 Injuries to the thorax	0.948	0.052
E11.4 With neurological complications	0.944	0.056
I80 Phlebitis and thrombophlebitis	0.941	0.059
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.936	0.064
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.936	0.064
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.929	0.071
Chapter XXI Factors influencing health status and contact with health services	0.929	0.071
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.927	0.073
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.924	0.076
I70-I79 Diseases of arteries, arterioles and capillaries	0.923	0.077
S61 Open wound of wrist and hand	0.912	0.088
K70.9 Alcoholic liver disease, unspecified	0.912	0.088
E11.9 Without complications	0.909	0.091
Chapter X Diseases of the respiratory system	0.908	0.092
C18 Malignant neoplasm of colon	0.906	0.094
E20-E35 Disorders of other endocrine glands	0.905	0.095
Z70-Z76 Persons encountering health services in other circumstances	0.905	0.095
K50-K52 Noninfective enteritis and colitis	0.904	0.096
C25.0 Head of pancreas	0.898	0.102
J09-J18 Influenza and pneumonia	0.897	0.103
I63 Cerebral infarction	0.897	0.103
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.891	0.109
I26 Pulmonary embolism	0.889	0.111
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.886	0.114
I69 Sequelae of cerebrovascular disease	0.886	0.114
J18 Pneumonia, organism unspecified	0.884	0.116
K86 Other diseases of pancreas	0.882	0.118
Z72 Problems related to lifestyle	0.881	0.119
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.879	0.121
W20-W49 Exposure to inanimate mechanical forces	0.874	0.126
I21 Acute myocardial infarction	0.874	0.126
C25.9 Pancreas, unspecified	0.872	0.128
I60 Subarachnoid haemorrhage	0.871	0.129
S20 Superficial injury of thorax	0.870	0.130
S80-S89 Injuries to the knee and lower leg	0.868	0.132
E11.3 With ophthalmic complications	0.863	0.137
Z72.1 Alcohol use	0.863	0.137
I64 Stroke, not specified as haemorrhage or infarction	0.862	0.138
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.858	0.142
Z00-Z13 Persons encountering health services for examination and investigation	0.858	0.142
Chapter VIII Diseases of the ear and mastoid process	0.856	0.144
I25.2 Old myocardial infarction	0.856	0.144
S90-S99 Injuries to the ankle and foot	0.854	0.146
J18.1 Lobar pneumonia, unspecified	0.854	0.146
S50-S59 Injuries to the elbow and forearm	0.854	0.146
K76 Other diseases of liver	0.853	0.147
I71 Aortic aneurysm and dissection	0.853	0.147
T15-T19 Effects of foreign body entering through natural orifice	0.852	0.148
K74 Fibrosis and cirrhosis of liver	0.848	0.152
K51 Ulcerative colitis	0.847	0.153
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.844	0.156
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.842	0.158
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.841	0.159
C15 Malignant neoplasm of oesophagus	0.839	0.161
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.834	0.166
Chapter VI Diseases of the nervous system	0.832	0.168
K70.3 Alcoholic cirrhosis of liver	0.830	0.170
I24 Other acute ischaemic heart diseases	0.830	0.170
I10-I15 Hypertensive diseases	0.829	0.171
E70-E90 Metabolic disorders	0.828	0.172
I27 Other pulmonary heart diseases	0.826	0.174
I20.1 Angina pectoris with documented spasm	0.826	0.174
I25.9 Chronic ischaemic heart disease, unspecified	0.826	0.174
B35-B49 Mycoses	0.826	0.174
S40-S49 Injuries to the shoulder and upper arm	0.824	0.176
O30 Multiple gestation	0.824	0.176
E10.1 With ketoacidosis	0.823	0.177
C43-C44 Melanoma and other malignant neoplasms of skin	0.823	0.177
C77.5 Intrapelvic lymph nodes	0.823	0.177
E11.2 With renal complications	0.820	0.180
I21.0 Acute transmural myocardial infarction of anterior wall	0.820	0.180
E50-E64 Other nutritional deficiencies	0.819	0.181
J18.9 Pneumonia, unspecified	0.819	0.181
K83 Other diseases of biliary tract	0.818	0.182
C77.2 Intra-abdominal lymph nodes	0.810	0.190
C64-C68 Malignant neoplasms of urinary tract	0.810	0.190
I82 Other venous embolism and thrombosis	0.810	0.190
S61.0 Open wound of finger(s) without damage to nail	0.808	0.192
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.808	0.192
S22 Fracture of rib(s), sternum and thoracic spine	0.807	0.193
I61 Intracerebral haemorrhage	0.806	0.194
C18.9 Colon, unspecified	0.805	0.195
I62 Other nontraumatic intracranial haemorrhage	0.804	0.196
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.804	0.196
E10.3 With ophthalmic complications	0.803	0.197
S20.8 Superficial injuries of other and unspecified parts of thorax	0.799	0.201
C78.4 Secondary malignant neoplasm of small intestine	0.799	0.201
S66 Injury of muscle and tendon at wrist and hand level	0.797	0.203
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.797	0.203
E11.6 With other specified complications	0.795	0.205
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.795	0.205
K85 Acute pancreatitis	0.795	0.205
Y44 Agents primarily affecting blood constituents	0.794	0.206
K70.1 Alcoholic hepatitis	0.790	0.210
I77 Other disorders of arteries and arterioles	0.790	0.210
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.789	0.211
E11.5 With peripheral circulatory complications	0.788	0.212
V20-V29 Motorcycle rider injured in transport accident	0.788	0.212
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.788	0.212
Z03 Medical observation and evaluation for suspected diseases and conditions	0.787	0.213
I63.9 Cerebral infarction, unspecified	0.787	0.213
K82 Other diseases of gallbladder	0.786	0.214
S62 Fracture at wrist and hand level	0.784	0.216
K76.6 Portal hypertension	0.783	0.217
O42 Premature rupture of membranes	0.782	0.218
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.782	0.218
I88 Nonspecific lymphadenitis	0.780	0.220
C77.9 Lymph node, unspecified	0.779	0.221
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.779	0.221
K86.1 Other chronic pancreatitis	0.778	0.222
C26 Malignant neoplasm of other and ill-defined digestive organs	0.777	0.223
I95-I99 Other and unspecified disorders of the circulatory system	0.774	0.226
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.774	0.226
I25.8 Other forms of chronic ischaemic heart disease	0.773	0.227
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.772	0.228
K74.6 Other and unspecified cirrhosis of liver	0.771	0.229
K70.4 Alcoholic hepatic failure	0.770	0.230
S70-S79 Injuries to the hip and thigh	0.769	0.231
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.769	0.231
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.765	0.235
B15-B19 Viral hepatitis	0.765	0.235
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.764	0.235
E13 Other specified diabetes mellitus	0.764	0.236
E87 Other disorders of fluid, electrolyte and acid-base balance	0.764	0.236
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.764	0.236
I24.9 Acute ischaemic heart disease, unspecified	0.763	0.237
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.762	0.237
C51-C58 Malignant neoplasms of female genital organs	0.762	0.238
X40-X49 Accidental poisoning by and exposure to noxious substances	0.762	0.238
S68 Traumatic amputation of wrist and hand	0.761	0.239
O35 Maternal care for known or suspected foetal abnormality and damage	0.760	0.240
O85-O92 Complications predominantly related to the puerperium	0.760	0.240
Z03.4 Observation for suspected myocardial infarction	0.760	0.240
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.759	0.241
I22 Subsequent myocardial infarction	0.758	0.242
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.758	0.242
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.757	0.243
S61.1 Open wound of finger(s) with damage to nail	0.756	0.244
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.755	0.245
O32 Maternal care for known or suspected malpresentation of foetus	0.753	0.247
I25.3 Aneurysm of heart	0.753	0.247
A80-A89 Viral infections of the central nervous system	0.752	0.248
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.752	0.248
T79-T79 Certain early complications of trauma	0.752	0.248
H90-H95 Other disorders of ear	0.751	0.249
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.751	0.249
O30.0 Twin pregnancy	0.750	0.250
C78.0 Secondary malignant neoplasm of lung	0.750	0.250
K83.1 Obstruction of bile duct	0.749	0.251
Z73 Problems related to life-management difficulty	0.746	0.254
K72 Hepatic failure, not elsewhere classified	0.745	0.255
Y57 Other and unspecified drugs and medicaments	0.744	0.256
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.743	0.257
S64 Injury of nerves at wrist and hand level	0.741	0.259
T18 Foreign body in alimentary tract	0.740	0.260
I70 Atherosclerosis	0.739	0.261
C21 Malignant neoplasm of anus and anal canal	0.739	0.261
C44 Other malignant neoplasms of skin	0.738	0.262
W44 Foreign body entering into or through eye or natural orifice	0.738	0.262
B20-B24 Human immunodeficiency virus [HIV] disease	0.737	0.263
S10-S19 Injuries to the neck	0.736	0.264
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.736	0.264
Chapter XXII Codes for special purposes	0.734	0.266
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.733	0.267
H60-H62 Diseases of external ear	0.733	0.267
E27 Other disorders of adrenal gland	0.732	0.268
K86.0 Alcohol-induced chronic pancreatitis	0.732	0.268
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.732	0.268
Y84.8 Other medical procedures	0.732	0.268
C18.4 Transverse colon	0.731	0.269
E23 Hypofunction and other disorders of pituitary gland	0.731	0.269
K75 Other inflammatory liver diseases	0.729	0.270
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.729	0.271
S90 Superficial injury of ankle and foot	0.729	0.271
I27.0 Primary pulmonary hypertension	0.729	0.271
C78.2 Secondary malignant neoplasm of pleura	0.728	0.272
I87 Other disorders of veins	0.727	0.272
K51.8 Other ulcerative colitis	0.726	0.274
C77.4 Inguinal and lower limb lymph nodes	0.726	0.274
I69.3 Sequelae of cerebral infarction	0.719	0.281
I85 Oesophageal varices	0.719	0.281
B37 Candidiasis	0.718	0.282
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
E12 Malnutrition-related diabetes mellitus	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
S61.8 Open wound of other parts of wrist and hand	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.716	0.283
C15.9 Oesophagus, unspecified	0.716	0.284
S60 Superficial injury of wrist and hand	0.716	0.284
Y52 Agents primarily affecting the cardiovascular system	0.716	0.284
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.715	0.285
O36 Maternal care for other known or suspected foetal problems	0.714	0.285
E24 Cushing's syndrome	0.714	0.286
E11.8 With unspecified complications	0.714	0.286
E11.7 With multiple complications	0.714	0.286
E11.1 With ketoacidosis	0.714	0.286
E11.0 With coma	0.714	0.286
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.714	0.286
Y60-Y69 Misadventures to patients during surgical and medical care	0.714	0.286
J15 Bacterial pneumonia, not elsewhere classified	0.714	0.286
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.714	0.286
C40-C41 Malignant neoplasms of bone and articular cartilage	0.714	0.286
Z72.2 Drug use	0.713	0.287
I68 Cerebrovascular disorders in diseases classified elsewhere	0.713	0.287
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.713	0.287
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.712	0.288
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.712	0.288
Y84.2 Radiological procedure and radiotherapy	0.712	0.288
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.711	0.288
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.711	0.289
K51.0 Ulcerative (chronic) enterocolitis	0.711	0.289
S51 Open wound of forearm	0.711	0.289
C18.5 Splenic flexure	0.709	0.291
I71.0 Dissection of aorta [any part]	0.709	0.291
I67 Other cerebrovascular diseases	0.709	0.291
E10.8 With unspecified complications	0.708	0.291
E10.7 With multiple complications	0.708	0.291
E10.6 With other specified complications	0.708	0.291
E10.5 With peripheral circulatory complications	0.708	0.291
E10.2 With renal complications	0.708	0.291
E10.0 With coma	0.708	0.291
O41 Other disorders of amniotic fluid and membranes	0.708	0.292
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.706	0.293
C16 Malignant neoplasm of stomach	0.706	0.293
C77.8 Lymph nodes of multiple regions	0.706	0.294
J14 Pneumonia due to Haemophilus influenzae	0.706	0.294
K86.3 Pseudocyst of pancreas	0.706	0.294
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.705	0.295
Y35-Y36 Legal intervention and operations of war	0.705	0.295
Y10-Y34 Event of undetermined intent	0.705	0.295
Y00-Y09 Assault	0.705	0.295
X85-X99 Assault	0.705	0.295
X58-X59 Accidental exposure to other and unspecified factors	0.705	0.295
X50-X57 Overexertion, travel and privation	0.705	0.295
X30-X39 Exposure to forces of nature	0.705	0.295
X20-X29 Contact with venomous animals and plants	0.705	0.295
X10-X19 Contact with heat and hot substances	0.705	0.295
X00-X09 Exposure to smoke, fire and flames	0.705	0.295
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.705	0.295
W75-W84 Other accidental threats to breathing	0.705	0.295
W65-W74 Accidental drowning and submersion	0.705	0.295
W50-W64 Exposure to animate mechanical forces	0.705	0.295
V98-V99 Other and unspecified transport accidents	0.705	0.295
V95-V97 Air and space transport accidents	0.705	0.295
V90-V94 Water transport accidents	0.705	0.295
V80-V89 Other land transport accidents	0.705	0.295
V70-V79 Bus occupant injured in transport accident	0.705	0.295
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.705	0.295
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.705	0.295
V40-V49 Car occupant injured in transport accident	0.705	0.295
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.705	0.295
V01-V09 Pedestrian injured in transport accident	0.705	0.295
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.705	0.295
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.705	0.295
C17 Malignant neoplasm of small intestine	0.705	0.295
C23 Malignant neoplasm of gallbladder	0.705	0.295
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.705	0.295
S61.7 Multiple open wounds of wrist and hand	0.705	0.295
E40-E46 Malnutrition	0.704	0.295
B97 Viral agents as the cause of diseases classified to other chapters	0.704	0.296
S27 Injury of other and unspecified intrathoracic organs	0.704	0.296
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.704	0.296
C67 Malignant neoplasm of bladder	0.704	0.296
T86 Failure and rejection of transplanted organs and tissues	0.704	0.296
I82.8 Embolism and thrombosis of other specified veins	0.704	0.296
E87.1 Hypo-osmolality and hyponatraemia	0.703	0.297
A30-A49 Other bacterial diseases	0.703	0.297
E10.4 With neurological complications	0.703	0.297
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.702	0.298
O60-O75 Complications of labour and delivery	0.701	0.299
S67 Crushing injury of wrist and hand	0.701	0.299
S65 Injury of blood vessels at wrist and hand level	0.701	0.299
C76 Malignant neoplasm of other and ill-defined sites	0.700	0.300
B99-B99 Other infectious diseases	0.700	0.300
B90-B94 Sequelae of infectious and parasitic diseases	0.700	0.300
B85-B89 Pediculosis, acariasis and other infestations	0.700	0.300
B65-B83 Helminthiases	0.700	0.300
B50-B64 Protozoal diseases	0.700	0.300
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.700	0.300
A75-A79 Rickettsioses	0.700	0.300
A70-A74 Other diseases caused by chlamydiae	0.700	0.300
A65-A69 Other spirochaetal diseases	0.700	0.300
A20-A28 Certain zoonotic bacterial diseases	0.700	0.300
A15-A19 Tuberculosis	0.700	0.300
I71.3 Abdominal aortic aneurysm, ruptured	0.700	0.300
A50-A64 Infections with a predominantly sexual mode of transmission	0.699	0.300
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.699	0.301
K77 Liver disorders in diseases classified elsewhere	0.698	0.301
K73 Chronic hepatitis, not elsewhere classified	0.698	0.301
K71 Toxic liver disease	0.698	0.301
J30-J39 Other diseases of upper respiratory tract	0.698	0.302
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.696	0.304
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.696	0.304
I69.1 Sequelae of intracerebral haemorrhage	0.695	0.305
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.695	0.305
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.693	0.307
Y44.2 Anticoagulants	0.692	0.308
C18.2 Ascending colon	0.692	0.308
C44.1 Skin of eyelid, including canthus	0.692	0.308
W25 Contact with sharp glass	0.690	0.310
Y43 Primarily systemic agents	0.689	0.311
K70.2 Alcoholic fibrosis and sclerosis of liver	0.688	0.312
K70.0 Alcoholic fatty liver	0.688	0.312
Z76 Persons encountering health services in other circumstances	0.688	0.312
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.688	0.312
C77.1 Intrathoracic lymph nodes	0.688	0.312
Y40 Systemic antibiotics	0.687	0.312
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.687	0.313
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.687	0.313
I81 Portal vein thrombosis	0.686	0.314
C25.8 Overlapping lesion of pancreas	0.686	0.314
C25.7 Other parts of pancreas	0.686	0.314
C25.4 Endocrine pancreas	0.686	0.314
C25.3 Pancreatic duct	0.686	0.314
C25.2 Tail of pancreas	0.686	0.314
C25.1 Body of pancreas	0.686	0.314
I28 Other diseases of pulmonary vessels	0.685	0.315
K51.2 Ulcerative (chronic) proctitis	0.685	0.315
K51.4 Pseudopolyposis of colon	0.685	0.315
O34 Maternal care for known or suspected abnormality of pelvic organs	0.685	0.315
I25.6 Silent myocardial ischaemia	0.685	0.315
I25.4 Coronary artery aneurysm	0.685	0.315
I25.0 Atherosclerotic cardiovascular disease, so described	0.685	0.315
Y42.5 Other oestrogens and progestogens	0.685	0.315
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.684	0.316
K82.8 Other specified diseases of gallbladder	0.683	0.317
W49 Exposure to other and unspecified inanimate mechanical forces	0.683	0.317
Z12 Special screening examination for neoplasms	0.683	0.317
E29 Testicular dysfunction	0.683	0.317
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.683	0.317
S81 Open wound of lower leg	0.682	0.318
S69 Other and unspecified injuries of wrist and hand	0.681	0.318
G30-G32 Other degenerative diseases of the nervous system	0.681	0.319
O00-O08 Pregnancy with abortive outcome	0.680	0.320
S29 Other and unspecified injuries of thorax	0.679	0.320
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.679	0.320
S26 Injury of heart	0.679	0.320
S25 Injury of blood vessels of thorax	0.679	0.320
S24 Injury of nerves and spinal cord at thorax level	0.679	0.320
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.679	0.320
S21 Open wound of thorax	0.679	0.320
D00-D09 In situ neoplasms	0.679	0.321
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.679	0.321
K76.9 Liver disease, unspecified	0.679	0.321
S52 Fracture of forearm	0.678	0.322
E55 Vitamin D deficiency	0.677	0.322
O47 False labour	0.677	0.323
I86 Varicose veins of other sites	0.677	0.323
O48 Prolonged pregnancy	0.677	0.323
I77.6 Arteritis, unspecified	0.677	0.323
E86 Volume depletion	0.675	0.325
S20.2 Contusion of thorax	0.675	0.325
I80.8 Phlebitis and thrombophlebitis of other sites	0.675	0.325
Z29 Need for other prophylactic measures	0.675	0.325
I21.2 Acute transmural myocardial infarction of other sites	0.674	0.326
S30 Superficial injury of abdomen, lower back and pelvis	0.674	0.326
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.673	0.327
Y84.0 Cardiac catheterisation	0.673	0.327
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.673	0.327
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.673	0.327
E14 Unspecified diabetes mellitus	0.672	0.328
H91 Other hearing loss	0.672	0.328
T66-T78 Other and unspecified effects of external causes	0.671	0.328
I98 Other disorders of circulatory system in diseases classified elsewhere	0.672	0.328
Y59 Other and unspecified vaccines and biological substances	0.671	0.329
Y58 Bacterial vaccines	0.671	0.329
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.671	0.329
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.671	0.329
Y53 Agents primarily affecting the gastro-intestinal system	0.671	0.329
Y50 Central nervous system stimulants, not elsewhere classified	0.671	0.329
Y49 Psychotropic drugs, not elsewhere classified	0.671	0.329
Y48 Anaesthetics and therapeutic gases	0.671	0.329
Y47 Sedatives, hypnotics and antianxiety drugs	0.671	0.329
Y46 Antiepileptics and anti-Parkinsonism drugs	0.671	0.329
Y41 Other systemic anti-infectives and antiparasitics	0.671	0.329
I61.9 Intracerebral haemorrhage, unspecified	0.671	0.329
J11 Influenza, virus not identified	0.671	0.329
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.671	0.329
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.669	0.331
K86.9 Disease of pancreas, unspecified	0.669	0.331
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.668	0.332
I25.1 Atherosclerotic heart disease	0.668	0.332
I15 Secondary hypertension	0.667	0.333
S22.3 Fracture of rib	0.666	0.333
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.666	0.334
C78.1 Secondary malignant neoplasm of mediastinum	0.666	0.334
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.666	0.334
K50 Crohn's disease [regional enteritis]	0.666	0.334
G62 Other polyneuropathies	0.665	0.335
G60 Hereditary and idiopathic neuropathy	0.665	0.335
O45 Premature separation of placenta [abruptio placentae]	0.665	0.335
O44 Placenta praevia	0.665	0.335
O43 Placental disorders	0.665	0.335
O33 Maternal care for known or suspected disproportion	0.665	0.335
O31 Complications specific to multiple gestation	0.665	0.335
O40 Polyhydramnios	0.665	0.335
J60-J70 Lung diseases due to external agents	0.665	0.335
Z02 Examination and encounter for administrative purposes	0.664	0.336
C18.6 Descending colon	0.664	0.336
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.662	0.337
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.662	0.338
I72 Other aneurysm	0.662	0.338
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.662	0.338
T80 Complications following infusion, transfusion and therapeutic injection	0.662	0.338
I69.0 Sequelae of subarachnoid haemorrhage	0.660	0.340
I20.8 Other forms of angina pectoris	0.659	0.340
O80-O84 Delivery	0.659	0.340
T18.1 Foreign body in oesophagus	0.659	0.341
X60-X84 Intentional self-harm	0.659	0.341
Z03.5 Observation for other suspected cardiovascular diseases	0.659	0.341
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.658	0.342
E87.7 Fluid overload	0.658	0.342
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.655	0.344
G00-G09 Inflammatory diseases of the central nervous system	0.655	0.344
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.655	0.345
E87.2 Acidosis	0.655	0.345
C50-C50 Malignant neoplasm of breast	0.654	0.346
S40 Superficial injury of shoulder and upper arm	0.654	0.346
S92 Fracture of foot, except ankle	0.653	0.347
H61 Other disorders of external ear	0.653	0.347
I88.9 Nonspecific lymphadenitis, unspecified	0.652	0.348
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.652	0.348
W29 Contact with other powered hand tools and household machinery	0.652	0.348
K52 Other non-infective gastro-enteritis and colitis	0.651	0.349
T87 Complications peculiar to reattachment and amputation	0.651	0.349
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.650	0.350
C18.8 Overlapping lesion of colon	0.650	0.350
C18.3 Hepatic flexure	0.650	0.350
C18.1 Appendix	0.650	0.350
E35 Disorders of endocrine glands in diseases classified elsewhere	0.649	0.351
E34 Other endocrine disorders	0.649	0.351
E32 Diseases of thymus	0.649	0.351
E31 Polyglandular dysfunction	0.649	0.351
E30 Disorders of puberty, not elsewhere classified	0.649	0.351
E26 Hyperaldosteronism	0.649	0.351
E25 Adrenogenital disorders	0.649	0.351
E20 Hypoparathyroidism	0.649	0.351
Z70 Counselling related to sexual attitude, behaviour and orientation	0.649	0.351
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.649	0.351
G90-G99 Other disorders of the nervous system	0.649	0.351
E22 Hyperfunction of pituitary gland	0.649	0.351
I05-I09 Chronic rheumatic heart diseases	0.649	0.351
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.648	0.351
J10 Influenza due to identified influenza virus	0.647	0.353
V10-V19 Pedal cyclist injured in transport accident	0.647	0.353
Z74 Problems related to care-provider dependency	0.646	0.354
Z09.2 Follow-up examination after chemotherapy for other conditions	0.646	0.354
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.644	0.355
K85.9 Acute pancreatitis, unspecified	0.644	0.356
S80 Superficial injury of lower leg	0.644	0.356
J17 Pneumonia in diseases classified elsewhere	0.643	0.357
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.643	0.357
J12 Viral pneumonia, not elsewhere classified	0.643	0.357
J09 Influenza due to certain identified influenza virus	0.643	0.357
K85.1 Biliary acute pancreatitis	0.643	0.357
E28 Ovarian dysfunction	0.643	0.357
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.643	0.357
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.643	0.357
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.643	0.357
S82 Fracture of lower leg, including ankle	0.643	0.357
S46 Injury of muscle and tendon at shoulder and upper arm level	0.642	0.358
C44.5 Skin of trunk	0.642	0.358
I12 Hypertensive renal disease	0.642	0.358
Y54.4 Loop [high-ceiling] diuretics	0.641	0.359
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.641	0.359
K86.2 Cyst of pancreas	0.640	0.360
W44.0 Home	0.640	0.360
C01 Malignant neoplasm of base of tongue	0.640	0.360

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations