TreeWAS – Variant ID: rs75033941

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter VI Diseases of the nervous system	0.999	0.001
Chapter XV Pregnancy, childbirth and the puerperium	0.999	0.001
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.996	0.004
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.996	0.004
Chapter XIV Diseases of the genitourinary system	0.995	0.005
Chapter IV Endocrine, nutritional and metabolic diseases	0.995	0.005
M05-M14 Inflammatory polyarthropathies	0.993	0.007
M06 Other rheumatoid arthritis	0.992	0.008
O60-O75 Complications of labour and delivery	0.992	0.008
M06.9 Rheumatoid arthritis, unspecified	0.991	0.009
E70-E90 Metabolic disorders	0.990	0.010
Chapter I Certain infectious and parasitic diseases	0.990	0.010
N17-N19 Renal failure	0.985	0.015
E87 Other disorders of fluid, electrolyte and acid-base balance	0.984	0.016
Chapter II Neoplasms	0.982	0.018
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.982	0.018
N17 Acute renal failure	0.981	0.019
A00-A09 Intestinal infectious diseases	0.980	0.020
N17.9 Acute renal failure, unspecified	0.979	0.021
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.978	0.022
G40-G47 Episodic and paroxysmal disorders	0.977	0.023
Chapter VIII Diseases of the ear and mastoid process	0.977	0.023
G20-G26 Extrapyramidal and movement disorders	0.972	0.028
E87.6 Hypokalaemia	0.964	0.036
D37-D48 Neoplasms of uncertain or unknown behaviour	0.961	0.039
S00-S09 Injuries to the head	0.957	0.043
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.955	0.045
O68 Labour and delivery complicated by foetal stress [distress]	0.953	0.047
H65-H75 Diseases of middle ear and mastoid	0.952	0.048
R50-R69 General symptoms and signs	0.948	0.052
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.947	0.053
S80-S89 Injuries to the knee and lower leg	0.946	0.054
G20 Parkinson's disease	0.937	0.063
M65-M68 Disorders of synovium and tendon	0.936	0.064
N80-N98 Noninflammatory disorders of female genital tract	0.932	0.068
Chapter XII Diseases of the skin and subcutaneous tissue	0.924	0.076
A09.9 Gastroenteritis and colitis of unspecified origin	0.923	0.077
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.921	0.079
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.918	0.082
R55 Syncope and collapse	0.911	0.089
Chapter XXI Factors influencing health status and contact with health services	0.911	0.089
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.910	0.090
A04 Other bacterial intestinal infections	0.909	0.091
O20-O29 Other maternal disorders predominantly related to pregnancy	0.906	0.094
R72 Abnormality of white blood cells, not elsewhere classified	0.900	0.100
D45 Polycythaemia vera	0.898	0.102
S82 Fracture of lower leg, including ankle	0.898	0.102
E83 Disorders of mineral metabolism	0.895	0.105
G47 Sleep disorders	0.895	0.105
G90-G99 Other disorders of the nervous system	0.894	0.106
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.893	0.107
Chapter X Diseases of the respiratory system	0.890	0.110
N10-N16 Renal tubulo-interstitial diseases	0.889	0.111
N00-N08 Glomerular diseases	0.885	0.115
O70 Perineal laceration during delivery	0.885	0.115
M65 Synovitis and tenosynovitis	0.884	0.116
C43-C44 Melanoma and other malignant neoplasms of skin	0.882	0.118
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.882	0.118
R63 Symptoms and signs concerning food and fluid intake	0.876	0.124
O94-O99 Other obstetric conditions, not elsewhere classified	0.875	0.125
S09 Other and unspecified injuries of head	0.875	0.125
H72 Perforation of tympanic membrane	0.874	0.126
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.874	0.126
Z40-Z54 Persons encountering health services for specific procedures and health care	0.873	0.127
E86 Volume depletion	0.868	0.132
S40-S49 Injuries to the shoulder and upper arm	0.865	0.135
C90 Multiple myeloma and malignant plasma cell neoplasms	0.863	0.137
S82.8 Fractures of other parts of lower leg	0.861	0.139
E50-E64 Other nutritional deficiencies	0.857	0.143
J90-J94 Other diseases of pleura	0.855	0.145
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.854	0.146
H66 Suppurative and unspecified otitis media	0.854	0.146
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.850	0.150
L80-L99 Other disorders of the skin and subcutaneous tissue	0.850	0.150
R79 Other abnormal findings of blood chemistry	0.848	0.152
Z50 Care involving use of rehabilitation procedures	0.848	0.152
R63.0 Anorexia	0.844	0.156
G47.3 Sleep apnoea	0.841	0.159
E20-E35 Disorders of other endocrine glands	0.836	0.164
S60-S69 Injuries to the wrist and hand	0.836	0.164
S00 Superficial injury of head	0.836	0.164
S82.80 Fractures of other parts of lower leg (closed)	0.835	0.165
N95 Menopausal and other perimenopausal disorders	0.834	0.166
N20-N23 Urolithiasis	0.831	0.169
Chapter IX Diseases of the circulatory system	0.830	0.170
G40 Epilepsy	0.827	0.173
G00-G09 Inflammatory diseases of the central nervous system	0.827	0.173
M80-M85 Disorders of bone density and structure	0.826	0.174
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.826	0.174
N84 Polyp of female genital tract	0.826	0.174
O26 Maternal care for other conditions predominantly related to pregnancy	0.825	0.175
N90 Other noninflammatory disorders of vulva and perineum	0.824	0.176
E87.2 Acidosis	0.823	0.177
G30-G32 Other degenerative diseases of the nervous system	0.823	0.177
A04.5 Campylobacter enteritis	0.822	0.178
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.822	0.178
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.817	0.183
R56 Convulsions, not elsewhere classified	0.816	0.184
T66-T78 Other and unspecified effects of external causes	0.816	0.184
S09.9 Unspecified injury of head	0.816	0.184
Z50.8 Care involving use of rehabilitation procedures	0.816	0.184
O64 Obstructed labour due to malposition and malpresentation of foetus	0.815	0.185
B65-B83 Helminthiases	0.814	0.186
Z48 Other surgical follow-up care	0.813	0.187
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.810	0.190
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.805	0.195
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.804	0.196
O70.1 Second degree perineal laceration during delivery	0.803	0.197
S06 Intracranial injury	0.803	0.197
H72.9 Perforation of tympanic membrane, unspecified	0.803	0.197
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.802	0.198
M65.9 Synovitis and tenosynovitis, unspecified	0.799	0.201
G45 Transient cerebral ischaemic attacks and related syndromes	0.799	0.201
N94.1 Dyspareunia	0.797	0.203
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.797	0.203
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.797	0.203
I70-I79 Diseases of arteries, arterioles and capillaries	0.796	0.204
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.796	0.204
L81 Other disorders of pigmentation	0.794	0.206
M91-M94 Chondropathies	0.793	0.207
E83.4 Disorders of magnesium metabolism	0.793	0.207
C50-C50 Malignant neoplasm of breast	0.792	0.207
R60 Oedema, not elsewhere classified	0.792	0.208
J90 Pleural effusion, not elsewhere classified	0.792	0.208
O75 Other complications of labour and delivery, not elsewhere classified	0.792	0.208
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.790	0.210
M06.0 Seronegative rheumatoid arthritis	0.789	0.211
C90.0 Multiple myeloma	0.789	0.211
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.787	0.213
Chapter XXII Codes for special purposes	0.786	0.214
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.785	0.215
G44 Other headache syndromes	0.785	0.215
H80-H83 Diseases of inner ear	0.783	0.217
N60-N64 Disorders of breast	0.783	0.217
H90-H95 Other disorders of ear	0.781	0.219
Z50.1 Other physical therapy	0.781	0.219
J00-J06 Acute upper respiratory infections	0.778	0.222
E87.0 Hyperosmolality and hypernatraemia	0.778	0.222
E87.3 Alkalosis	0.778	0.222
O66 Other obstructed labour	0.776	0.223
L20-L30 Dermatitis and eczema	0.776	0.224
R57 Shock, not elsewhere classified	0.775	0.225
O85-O92 Complications predominantly related to the puerperium	0.772	0.228
I30-I52 Other forms of heart disease	0.772	0.228
E83.3 Disorders of phosphorus metabolism	0.772	0.228
S50-S59 Injuries to the elbow and forearm	0.771	0.229
E87.5 Hyperkalaemia	0.771	0.229
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.770	0.229
N84.0 Polyp of corpus uteri	0.770	0.230
G25 Other extrapyramidal and movement disorders	0.770	0.230
Z33 Pregnant state, incidental	0.768	0.232
N89 Other noninflammatory disorders of vagina	0.767	0.233
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.767	0.233
G93 Other disorders of brain	0.767	0.233
G70-G73 Diseases of myoneural junction and muscle	0.766	0.233
S10-S19 Injuries to the neck	0.765	0.235
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.765	0.235
N94.6 Dysmenorrhoea, unspecified	0.765	0.235
C44 Other malignant neoplasms of skin	0.763	0.237
B95-B98 Bacterial, viral and other infectious agents	0.763	0.237
Z48.9 Surgical follow-up care, unspecified	0.763	0.237
O26.8 Other specified pregnancy-related conditions	0.762	0.238
M65.3 Trigger finger	0.762	0.238
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.760	0.240
Z34 Supervision of normal pregnancy	0.759	0.241
R73 Elevated blood glucose level	0.759	0.241
S80 Superficial injury of lower leg	0.758	0.242
G24 Dystonia	0.758	0.242
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.758	0.242
G43 Migraine	0.756	0.243
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.755	0.245
R53 Malaise and fatigue	0.755	0.245
O63 Long labour	0.754	0.245
Z35 Supervision of high-risk pregnancy	0.754	0.246
L81.4 Other melanin hyperpigmentation	0.754	0.246
M05 Seropositive rheumatoid arthritis	0.753	0.247
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.753	0.247
J91 Pleural effusion in conditions classified elsewhere	0.752	0.248
R59 Enlarged lymph nodes	0.748	0.252
A08 Viral and other specified intestinal infections	0.747	0.253
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.745	0.255
H73 Other disorders of tympanic membrane	0.745	0.255
Chapter V Mental and behavioural disorders	0.743	0.257
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.741	0.258
O69 Labour and delivery complicated by umbilical cord complications	0.741	0.259
R79.8 Other specified abnormal findings of blood chemistry	0.741	0.259
Z63 Other problems related to primary support group, including family circumstances	0.741	0.259
L60-L75 Disorders of skin appendages	0.741	0.259
S81 Open wound of lower leg	0.740	0.260
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.739	0.261
M15-M19 Arthrosis	0.738	0.262
N90.7 Vulvar cyst	0.738	0.262
N92 Excessive, frequent and irregular menstruation	0.737	0.263
G95 Other diseases of spinal cord	0.734	0.266
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.733	0.267
N03 Chronic nephritic syndrome	0.733	0.267
A50-A64 Infections with a predominantly sexual mode of transmission	0.733	0.267
H74 Other disorders of middle ear and mastoid	0.732	0.268
C43 Malignant melanoma of skin	0.732	0.268
H69 Other disorders of Eustachian tube	0.731	0.269
S82.6 Fracture of lateral malleolus	0.730	0.269
C81 Hodgkin's disease	0.730	0.270
S82.4 Fracture of fibula alone	0.729	0.271
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.729	0.271
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.729	0.271
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.727	0.273
Z51 Other medical care	0.727	0.273
C90.2 Plasmacytoma, extramedullary	0.727	0.273
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.726	0.274
T36-T50 Poisoning by drugs, medicaments and biological substances	0.726	0.274
O35 Maternal care for known or suspected foetal abnormality and damage	0.725	0.275
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.725	0.275
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.724	0.276
H66.9 Otitis media, unspecified	0.724	0.276
N90.5 Atrophy of vulva	0.724	0.276
H66.3 Other chronic suppurative otitis media	0.724	0.276
S66 Injury of muscle and tendon at wrist and hand level	0.722	0.278
R56.8 Other and unspecified convulsions	0.722	0.278
M11 Other crystal arthropathies	0.721	0.279
O46 Antepartum haemorrhage, not elsewhere classified	0.720	0.280
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.720	0.280
B90-B94 Sequelae of infectious and parasitic diseases	0.719	0.280
R41 Other symptoms and signs involving cognitive functions and awareness	0.719	0.281
M67 Other disorders of synovium and tendon	0.718	0.282
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.718	0.282
N88 Other noninflammatory disorders of cervix uteri	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
E23 Hypofunction and other disorders of pituitary gland	0.716	0.284
L91 Hypertrophic disorders of skin	0.715	0.285
T33-T35 Frostbite	0.714	0.285
T26-T28 Burns and corrosions confined to eye and internal organs	0.714	0.285
T20-T25 Burns and corrosions of external body surface, specified by site	0.714	0.285
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.714	0.285
T00-T07 Injuries involving multiple body regions	0.714	0.285
M60-M63 Disorders of muscles	0.714	0.286
M00-M03 Infectious arthropathies	0.714	0.286
A04.7 Enterocolitis due to Clostridium difficile	0.714	0.286
E40-E46 Malnutrition	0.713	0.287
T79-T79 Certain early complications of trauma	0.713	0.287
O73 Retained placenta and membranes, without haemorrhage	0.712	0.287
E55 Vitamin D deficiency	0.712	0.287
L29 Pruritus	0.712	0.288
M14 Arthropathies in other diseases classified elsewhere	0.712	0.288
M12 Other specific arthropathies	0.712	0.288
M09 Juvenile arthritis in diseases classified elsewhere	0.712	0.288
M08 Juvenile arthritis	0.712	0.288
N99-N99 Other disorders of the genitourinary system	0.712	0.288
A30-A49 Other bacterial diseases	0.711	0.289
M06.8 Other specified rheumatoid arthritis	0.711	0.289
M06.4 Inflammatory polyarthropathy	0.711	0.289
M06.3 Rheumatoid nodule	0.711	0.289
M06.2 Rheumatoid bursitis	0.711	0.289
M06.1 Adult-onset Still's disease	0.711	0.289
O74 Complications of anaesthesia during labour and delivery	0.711	0.289
O71 Other obstetric trauma	0.711	0.289
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.711	0.289
O65 Obstructed labour due to maternal pelvic abnormality	0.711	0.289
O61 Failed induction of labour	0.711	0.289
O60 Preterm delivery	0.711	0.289
E88 Other metabolic disorders	0.711	0.289
M06.98 Rheumatoid arthritis, unspecified (Other)	0.711	0.289
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.711	0.289
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.711	0.289
E85 Amyloidosis	0.710	0.290
E84 Cystic fibrosis	0.710	0.290
E79 Disorders of purine and pyrimidine metabolism	0.710	0.290
E77 Disorders of glycoprotein metabolism	0.710	0.290
E76 Disorders of glycosaminoglycan metabolism	0.710	0.290
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.710	0.290
E74 Other disorders of carbohydrate metabolism	0.710	0.290
E73 Lactose intolerance	0.710	0.290
E72 Other disorders of amino-acid metabolism	0.710	0.290
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.710	0.290
E70 Disorders of aromatic amino-acid metabolism	0.710	0.290
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.710	0.290
N18 Chronic renal failure	0.710	0.290
A04.8 Other specified bacterial intestinal infections	0.710	0.290
B99-B99 Other infectious diseases	0.709	0.290
B85-B89 Pediculosis, acariasis and other infestations	0.709	0.290
B50-B64 Protozoal diseases	0.709	0.290
B20-B24 Human immunodeficiency virus [HIV] disease	0.709	0.290
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.709	0.290
A80-A89 Viral infections of the central nervous system	0.709	0.290
A75-A79 Rickettsioses	0.709	0.290
A70-A74 Other diseases caused by chlamydiae	0.709	0.290
A65-A69 Other spirochaetal diseases	0.709	0.290
A20-A28 Certain zoonotic bacterial diseases	0.709	0.290
A15-A19 Tuberculosis	0.709	0.290
L50-L54 Urticaria and erythema	0.709	0.291
S90-S99 Injuries to the ankle and foot	0.708	0.292
E87.1 Hypo-osmolality and hyponatraemia	0.708	0.292
R27 Other lack of coordination	0.707	0.293
E87.7 Fluid overload	0.706	0.294
Z41 Procedures for purposes other than remedying health state	0.706	0.294
E87.4 Mixed disorder of acid-base balance	0.705	0.294
O62 Abnormalities of forces of labour	0.705	0.295
G35-G37 Demyelinating diseases of the central nervous system	0.705	0.295
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.704	0.296
C40-C41 Malignant neoplasms of bone and articular cartilage	0.704	0.296
R95-R99 Ill-defined and unknown causes of mortality	0.704	0.296
M86-M90 Other osteopathies	0.704	0.296
N17.8 Other acute renal failure	0.703	0.296
N17.2 Acute renal failure with medullary necrosis	0.703	0.296
N17.1 Acute renal failure with acute cortical necrosis	0.703	0.296
N17.0 Acute renal failure with tubular necrosis	0.703	0.296
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.703	0.297
S02 Fracture of skull and facial bones	0.703	0.297
A07 Other protozoal intestinal diseases	0.702	0.297
A06 Amoebiasis	0.702	0.297
A05 Other bacterial foodborne intoxications	0.702	0.297
A03 Shigellosis	0.702	0.297
A02 Other Salmonella infections	0.702	0.297
A01 Typhoid and paratyphoid fevers	0.702	0.297
A00 Cholera	0.702	0.297
I42 Cardiomyopathy	0.702	0.298
O23 Infections of genito-urinary tract in pregnancy	0.702	0.298
H65 Nonsuppurative otitis media	0.701	0.299
G46 Vascular syndromes of brain in cerebrovascular diseases	0.700	0.299
G41 Status epilepticus	0.700	0.299
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.700	0.300
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.699	0.301
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.698	0.302
N05 Unspecified nephritic syndrome	0.698	0.302
L89 Decubitus ulcer	0.698	0.302
G23 Other degenerative diseases of basal ganglia	0.697	0.303
G21 Secondary Parkinsonism	0.697	0.303
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.697	0.303
G22 Parkinsonism in diseases classified elsewhere	0.697	0.303
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.696	0.304
S70-S79 Injuries to the hip and thigh	0.695	0.304
C92 Myeloid leukaemia	0.695	0.305
R26 Abnormalities of gait and mobility	0.695	0.305
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.694	0.306
S42 Fracture of shoulder and upper arm	0.694	0.306
G45.9 Transient cerebral ischaemic attack, unspecified	0.694	0.306
M45-M49 Spondylopathies	0.692	0.308
R41.0 Disorientation, unspecified	0.692	0.308
Z54 Convalescence	0.691	0.309
I74 Arterial embolism and thrombosis	0.691	0.309
E53 Deficiency of other B group vitamins	0.691	0.309
N63 Unspecified lump in breast	0.691	0.309
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.691	0.309
J40-J47 Chronic lower respiratory diseases	0.690	0.310
N84.8 Polyp of other parts of female genital tract	0.690	0.310
N04 Nephrotic syndrome	0.690	0.310
J09-J18 Influenza and pneumonia	0.689	0.311
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.689	0.311
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.689	0.311
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.689	0.311
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.689	0.311
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.689	0.311
B80 Enterobiasis	0.688	0.312
O32 Maternal care for known or suspected malpresentation of foetus	0.688	0.312
B15-B19 Viral hepatitis	0.688	0.312
G99 Other disorders of nervous system in diseases classified elsewhere	0.688	0.312
N94.3 Premenstrual tension syndrome	0.688	0.312
S08 Traumatic amputation of part of head	0.686	0.313
S07 Crushing injury of head	0.686	0.313
S05 Injury of eye and orbit	0.686	0.313
S04 Injury of cranial nerves	0.686	0.313
S03 Dislocation, sprain and strain of joints and ligaments of head	0.686	0.313
S64 Injury of nerves at wrist and hand level	0.686	0.314
R78 Findings of drugs and other substances, not normally found in blood	0.685	0.315
R77 Other abnormalities of plasma proteins	0.685	0.315
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.685	0.315
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.685	0.315
R71 Abnormality of red blood cells	0.685	0.315
N95.8 Other specified menopausal and perimenopausal disorders	0.685	0.315
O24 Diabetes mellitus in pregnancy	0.685	0.315
D46 Myelodysplastic syndromes	0.684	0.316
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.683	0.316
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.682	0.317
H70 Mastoiditis and related conditions	0.682	0.317
H68 Eustachian salpingitis and obstruction	0.682	0.317
H67 Otitis media in diseases classified elsewhere	0.682	0.317
T68 Hypothermia	0.681	0.319
G04 Encephalitis, myelitis and encephalomyelitis	0.681	0.319
H72.0 Central perforation of tympanic membrane	0.680	0.320
B35-B49 Mycoses	0.680	0.320
O43 Placental disorders	0.680	0.320
G40.9 Epilepsy, unspecified	0.680	0.320
E83.1 Disorders of iron metabolism	0.680	0.320
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.679	0.320
R62 Lack of expected normal physiological development	0.679	0.320
R64 Cachexia	0.679	0.320
R58 Haemorrhage, not elsewhere classified	0.679	0.320
N95.0 Postmenopausal bleeding	0.679	0.321
S88 Traumatic amputation of lower leg	0.679	0.321
S87 Crushing injury of lower leg	0.679	0.321
S86 Injury of muscle and tendon at lower leg level	0.679	0.321
S85 Injury of blood vessels at lower leg level	0.679	0.321
S84 Injury of nerves at lower leg level	0.679	0.321
I73 Other peripheral vascular diseases	0.677	0.323
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.677	0.323
O75.8 Other specified complications of labour and delivery	0.674	0.326
M65.34 Trigger finger-Hand	0.674	0.326
S82.5 Fracture of medial malleolus	0.674	0.326
Z63.4 Disappearance and death of family member	0.674	0.326
O40 Polyhydramnios	0.674	0.326
O70.2 Third degree perineal laceration during delivery	0.674	0.326
R59.0 Localised enlarged lymph nodes	0.673	0.327
J94 Other pleural conditions	0.673	0.327
Z34.9 Supervision of normal pregnancy, unspecified	0.672	0.328
Z50.4 Psychotherapy, not elsewhere classified	0.672	0.328
S00.2 Other superficial injuries of eyelid and periocular area	0.672	0.328
N21 Calculus of lower urinary tract	0.671	0.329
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.671	0.329
M66 Spontaneous rupture of synovium and tendon	0.671	0.329
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.671	0.329
M16 Coxarthrosis [arthrosis of hip]	0.671	0.329
Z51.2 Other chemotherapy	0.671	0.329
S20-S29 Injuries to the thorax	0.670	0.329
L40-L45 Papulosquamous disorders	0.670	0.330
R76 Other abnormal immunological findings in serum	0.670	0.330
O47 False labour	0.670	0.330
G62 Other polyneuropathies	0.670	0.330
R52 Pain, not elsewhere classified	0.669	0.331
N98 Complications associated with artificial fertilisation	0.668	0.331
N91 Absent, scanty and rare menstruation	0.668	0.331
N82 Fistulae involving female genital tract	0.668	0.331
N96 Habitual aborter	0.668	0.331
N92.3 Ovulation bleeding	0.667	0.333
L95 Vasculitis limited to skin, not elsewhere classified	0.666	0.333
G93.8 Other specified disorders of brain	0.666	0.334
C91 Lymphoid leukaemia	0.666	0.334
Z32 Pregnancy examination and test	0.665	0.335
N89.8 Other specified noninflammatory disorders of vagina	0.665	0.335
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.665	0.335
N93 Other abnormal uterine and vaginal bleeding	0.665	0.335
C73 Malignant neoplasm of thyroid gland	0.664	0.336
E29 Testicular dysfunction	0.664	0.336
J00 Acute nasopharyngitis [common cold]	0.664	0.336
N20 Calculus of kidney and ureter	0.663	0.337
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.663	0.337
L10-L14 Bullous disorders	0.663	0.337
N83.2 Other and unspecified ovarian cysts	0.662	0.338
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.660	0.340
C95 Leukaemia of unspecified cell type	0.660	0.340
C94 Other leukaemias of specified cell type	0.660	0.340
C93 Monocytic leukaemia	0.660	0.340
C88 Malignant immunoproliferative diseases	0.660	0.340
C86 Other specified types of T/NK-cell lymphoma	0.660	0.340
C84 Peripheral and cutaneous T-cell lymphomas	0.660	0.340
I46 Cardiac arrest	0.660	0.340
D00-D09 In situ neoplasms	0.660	0.340
R60.9 Oedema, unspecified	0.660	0.340
M65.4 Radial styloid tenosynovitis [de Quervain]	0.659	0.341
C64-C68 Malignant neoplasms of urinary tract	0.657	0.343
H83 Other diseases of inner ear	0.657	0.343
R63.1 Polydipsia	0.657	0.343
C50 Malignant neoplasm of breast	0.657	0.343
E16 Other disorders of pancreatic internal secretion	0.655	0.345
O80-O84 Delivery	0.655	0.345
O64.1 Obstructed labour due to breech presentation	0.654	0.346
M18 Arthrosis of first carpometacarpal joint	0.654	0.346
R68 Other general symptoms and signs	0.653	0.347
R80 Isolated proteinuria	0.652	0.348
C44.7 Skin of lower limb, including hip	0.652	0.348
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.652	0.348
A04.9 Bacterial intestinal infection, unspecified	0.652	0.348
A04.6 Enteritis due to Yersinia enterocolitica	0.652	0.348
A04.4 Other intestinal Escherichia coli infections	0.652	0.348
A04.3 Enterohaemorrhagic Escherichia coli infection	0.652	0.348
A04.2 Enteroinvasive Escherichia coli infection	0.652	0.348
A04.1 Enterotoxigenic Escherichia coli infection	0.652	0.348
A04.0 Enteropathogenic Escherichia coli infection	0.652	0.348
R60.1 Generalised oedema	0.652	0.348
N08 Glomerular disorders in diseases classified elsewhere	0.651	0.348
R81 Glycosuria	0.651	0.349
R63.8 Other symptoms and signs concerning food and fluid intake	0.651	0.349
I35 Nonrheumatic aortic valve disorders	0.651	0.349
O29 Complications of anaesthesia during pregnancy	0.650	0.350
O28 Abnormal findings on antenatal screening of mother	0.650	0.350
O22 Venous complications in pregnancy	0.650	0.350
O21 Excessive vomiting in pregnancy	0.650	0.350
O25 Malnutrition in pregnancy	0.650	0.350
R74 Abnormal serum enzyme levels	0.649	0.351
D41.0 Kidney	0.649	0.351
Z51.4 Preparatory care for treatment, not elsewhere classified	0.649	0.351
M80 Osteoporosis with pathological fracture	0.649	0.351
B97 Viral agents as the cause of diseases classified to other chapters	0.649	0.351
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.647	0.353
G44.2 Tension-type headache	0.647	0.353
R79.0 Abnormal level of blood mineral	0.647	0.353
J92 Pleural plaque	0.646	0.354
N02 Recurrent and persistent haematuria	0.646	0.354
M40-M43 Deforming dorsopathies	0.646	0.354
S89 Other and unspecified injuries of lower leg	0.645	0.354
R79.9 Abnormal finding of blood chemistry, unspecified	0.645	0.355
S00.1 Contusion of eyelid and periocular area	0.644	0.355
B25-B34 Other viral diseases	0.644	0.356
N95.2 Postmenopausal atrophic vaginitis	0.644	0.356
L84 Corns and callosities	0.644	0.356
Z70-Z76 Persons encountering health services in other circumstances	0.644	0.356
S82.9 Fracture of lower leg, part unspecified	0.643	0.356
S82.7 Multiple fractures of lower leg	0.643	0.356
O63.1 Prolonged second stage (of labour)	0.644	0.356
N95.3 States associated with artificial menopause	0.643	0.357
D41.4 Bladder	0.643	0.357

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations