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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75063504
log Bayes Factor = 15.8981
Chromosome 4   position 61,731,645  (GRCh37) Explore rs75063504 on Ensembl!
Variant rs75063504 is part of Cluster X0045

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
Chapter X Diseases of the respiratory system
0.998 0.002 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.994 0.006 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.984 0.016 0.000
Chapter II Neoplasms
0.983 0.017 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.982 0.018 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.982 0.018 0.000
J30-J39 Other diseases of upper respiratory tract
0.981 0.019 0.000
Chapter V Mental and behavioural disorders
0.980 0.020 0.000
Chapter IX Diseases of the circulatory system
0.977 0.023 0.000
Chapter XI Diseases of the digestive system
0.973 0.027 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.973 0.027 0.000
Chapter VI Diseases of the nervous system
0.971 0.029 0.000
I30-I52 Other forms of heart disease
0.965 0.035 0.000
J40-J47 Chronic lower respiratory diseases
0.961 0.039 0.000
K70-K77 Diseases of liver
0.957 0.043 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.955 0.045 0.000
O60-O75 Complications of labour and delivery
0.953 0.047 0.000
K50-K52 Noninfective enteritis and colitis
0.949 0.051 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.947 0.053 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.944 0.056 0.000
J33 Nasal polyp
0.942 0.058 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.941 0.059 0.000
S00-S09 Injuries to the head
0.941 0.059 0.000
J44 Other chronic obstructive pulmonary disease
0.940 0.060 0.000
K76 Other diseases of liver
0.936 0.064 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.931 0.069 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.930 0.070 0.000
W00-W19 Falls
0.929 0.071 0.000
M50-M54 Other dorsopathies
0.928 0.072 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.927 0.073 0.000
R10 Abdominal and pelvic pain
0.926 0.074 0.000
K51 Ulcerative colitis
0.925 0.075 0.000
O70 Perineal laceration during delivery
0.924 0.076 0.000
G90-G99 Other disorders of the nervous system
0.924 0.076 0.000
C34 Malignant neoplasm of bronchus and lung
0.921 0.079 0.000
I44 Atrioventricular and left bundle-branch block
0.920 0.080 0.000
M20-M25 Other joint disorders
0.919 0.081 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.916 0.084 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.913 0.087 0.000
R11 Nausea and vomiting
0.910 0.090 0.000
O70.0 First degree perineal laceration during delivery
0.908 0.092 0.000
K51.9 Ulcerative colitis, unspecified
0.905 0.095 0.000
M15-M19 Arthrosis
0.904 0.095 0.000
M23 Internal derangement of knee
0.904 0.096 0.000
S01 Open wound of head
0.904 0.096 0.000
Chapter VII Diseases of the eye and adnexa
0.902 0.098 0.000
S60-S69 Injuries to the wrist and hand
0.899 0.101 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.894 0.106 0.000
J09-J18 Influenza and pneumonia
0.891 0.109 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.890 0.110 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.888 0.112 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.884 0.116 0.000
M17 Gonarthrosis [arthrosis of knee]
0.883 0.117 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.882 0.118 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.881 0.119 0.000
M05-M14 Inflammatory polyarthropathies
0.880 0.120 0.000
R10.1 Pain localised to upper abdomen
0.878 0.122 0.000
I44.7 Left bundle-branch block, unspecified
0.878 0.122 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.875 0.125 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.873 0.127 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.869 0.131 0.000
I35 Nonrheumatic aortic valve disorders
0.868 0.132 0.000
J33.0 Polyp of nasal cavity
0.867 0.133 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.864 0.136 0.000
J33.9 Nasal polyp, unspecified
0.864 0.136 0.000
G20-G26 Extrapyramidal and movement disorders
0.863 0.137 0.000
C64-C68 Malignant neoplasms of urinary tract
0.862 0.138 0.000
C51-C58 Malignant neoplasms of female genital organs
0.859 0.141 0.000
Y83.6 Removal of other organ (partial) (total)
0.856 0.144 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.856 0.144 0.000
C34.9 Bronchus or lung, unspecified
0.853 0.147 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.846 0.154 0.000
W19 Unspecified fall
0.845 0.155 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.844 0.156 0.000
M50 Cervical disk disorders
0.844 0.156 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.844 0.156 0.000
K50 Crohn's disease [regional enteritis]
0.841 0.159 0.000
I31 Other diseases of pericardium
0.841 0.159 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.839 0.161 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.837 0.163 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.836 0.164 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.833 0.167 0.000
M54 Dorsalgia
0.833 0.167 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.832 0.168 0.000
M80-M85 Disorders of bone density and structure
0.829 0.171 0.000
M17.1 Other primary gonarthrosis
0.829 0.171 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.827 0.172 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.827 0.173 0.000
F20 Schizophrenia
0.825 0.175 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.821 0.179 0.000
Chapter VIII Diseases of the ear and mastoid process
0.821 0.179 0.000
F17.1 Harmful use
0.821 0.179 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.817 0.183 0.000
S50-S59 Injuries to the elbow and forearm
0.816 0.184 0.000
T66-T78 Other and unspecified effects of external causes
0.816 0.184 0.000
Chapter I Certain infectious and parasitic diseases
0.816 0.184 0.000
J18 Pneumonia, organism unspecified
0.815 0.185 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.809 0.191 0.000
R15 Faecal incontinence
0.806 0.194 0.000
E70-E90 Metabolic disorders
0.806 0.194 0.000
H53-H54 Visual disturbances and blindness
0.803 0.197 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.802 0.198 0.000
W20-W49 Exposure to inanimate mechanical forces
0.801 0.198 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.799 0.201 0.000
C34.1 Upper lobe, bronchus or lung
0.797 0.203 0.000
M40-M43 Deforming dorsopathies
0.797 0.203 0.000
I44.0 Atrioventricular block, first degree
0.794 0.206 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.794 0.206 0.000
I35.0 Aortic (valve) stenosis
0.793 0.207 0.000
J00-J06 Acute upper respiratory infections
0.790 0.210 0.000
J35 Chronic diseases of tonsils and adenoids
0.790 0.210 0.000
Y83.8 Other surgical procedures
0.789 0.211 0.000
S01.0 Open wound of scalp
0.789 0.211 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.789 0.211 0.000
G30-G32 Other degenerative diseases of the nervous system
0.789 0.211 0.000
O36 Maternal care for other known or suspected foetal problems
0.784 0.216 0.000
K72 Hepatic failure, not elsewhere classified
0.784 0.216 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.783 0.217 0.000
I60-I69 Cerebrovascular diseases
0.781 0.219 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.781 0.219 0.000
J32 Chronic sinusitis
0.778 0.222 0.000
Y83.4 Other reconstructive surgery
0.777 0.223 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.772 0.228 0.000
C34.3 Lower lobe, bronchus or lung
0.772 0.228 0.000
Y83.0 Surgical operation with transplant of whole organ
0.771 0.229 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.771 0.229 0.000
S06 Intracranial injury
0.769 0.231 0.000
M54.9 Dorsalgia, unspecified
0.767 0.233 0.000
R94 Abnormal results of function studies
0.767 0.233 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.766 0.234 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.765 0.235 0.000
S20-S29 Injuries to the thorax
0.764 0.236 0.000
I31.3 Pericardial effusion (noninflammatory)
0.764 0.236 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.764 0.236 0.000
S61 Open wound of wrist and hand
0.764 0.236 0.000
M10 Gout
0.763 0.237 0.000
S01.8 Open wound of other parts of head
0.762 0.238 0.000
O47 False labour
0.761 0.239 0.000
J34 Other disorders of nose and nasal sinuses
0.761 0.239 0.000
J36 Peritonsillar abscess
0.758 0.242 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.758 0.242 0.000
G20 Parkinson's disease
0.757 0.243 0.000
C79 Secondary malignant neoplasm of other sites
0.756 0.244 0.000
J42 Unspecified chronic bronchitis
0.755 0.244 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.754 0.246 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.754 0.246 0.000
O63 Long labour
0.753 0.247 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.751 0.249 0.000
J60-J70 Lung diseases due to external agents
0.749 0.251 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.749 0.251 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.748 0.252 0.000
K50.9 Crohn's disease, unspecified
0.748 0.252 0.000
F10.0 Acute intoxication
0.748 0.252 0.000
E20-E35 Disorders of other endocrine glands
0.748 0.252 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.747 0.253 0.000
F20.9 Schizophrenia, unspecified
0.746 0.253 0.000
I30 Acute pericarditis
0.746 0.254 0.000
K75 Other inflammatory liver diseases
0.745 0.255 0.000
Y83.3 Surgical operation with formation of external stoma
0.744 0.256 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.744 0.256 0.000
M86-M90 Other osteopathies
0.743 0.257 0.000
K76.8 Other specified diseases of liver
0.743 0.257 0.000
D00-D09 In situ neoplasms
0.741 0.259 0.000
J18.1 Lobar pneumonia, unspecified
0.741 0.259 0.000
W08 Fall involving other furniture
0.740 0.260 0.000
M45-M49 Spondylopathies
0.739 0.261 0.000
X60-X84 Intentional self-harm
0.737 0.263 0.000
M50.0 Cervical disk disorder with myelopathy
0.736 0.264 0.000
G91 Hydrocephalus
0.736 0.264 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.735 0.265 0.000
V20-V29 Motorcycle rider injured in transport accident
0.734 0.266 0.000
K35-K38 Diseases of appendix
0.734 0.266 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.733 0.267 0.000
D60-D64 Aplastic and other anaemias
0.733 0.267 0.000
R04 Haemorrhage from respiratory passages
0.733 0.267 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.732 0.268 0.000
M17.0 Primary gonarthrosis, bilateral
0.732 0.268 0.000
I46 Cardiac arrest
0.732 0.268 0.000
R18 Ascites
0.732 0.268 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.731 0.269 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.730 0.269 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.730 0.270 0.000
I47 Paroxysmal tachycardia
0.730 0.270 0.000
S64 Injury of nerves at wrist and hand level
0.730 0.270 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.729 0.271 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.729 0.271 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.725 0.275 0.000
S01.3 Open wound of ear
0.724 0.276 0.000
G95 Other diseases of spinal cord
0.724 0.276 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.723 0.276 0.000
M65-M68 Disorders of synovium and tendon
0.723 0.277 0.000
J47 Bronchiectasis
0.722 0.278 0.000
M50.2 Other cervical disk displacement
0.722 0.278 0.000
H04 Disorders of lachrymal system
0.721 0.279 0.000
R19.5 Other fecal abnormalities
0.721 0.279 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.721 0.279 0.000
E50-E64 Other nutritional deficiencies
0.720 0.280 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.720 0.280 0.000
H53 Visual disturbances
0.720 0.280 0.000
E10-E14 Diabetes mellitus
0.719 0.281 0.000
O62 Abnormalities of forces of labour
0.719 0.281 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.719 0.281 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.719 0.281 0.000
C54 Malignant neoplasm of corpus uteri
0.718 0.282 0.000
J30 Vasomotor and allergic rhinitis
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S90-S99 Injuries to the ankle and foot
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
O70.2 Third degree perineal laceration during delivery
0.717 0.283 0.000
J39 Other diseases of upper respiratory tract
0.716 0.283 0.000
Chapter XIV Diseases of the genitourinary system
0.716 0.284 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.716 0.284 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
Y00-Y09 Assault
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.716 0.284 0.000
X50-X57 Overexertion, travel and privation
0.716 0.284 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X20-X29 Contact with venomous animals and plants
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
W50-W64 Exposure to animate mechanical forces
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V80-V89 Other land transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V40-V49 Car occupant injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V10-V19 Pedal cyclist injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.715 0.285 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.715 0.285 0.000
M91-M94 Chondropathies
0.715 0.285 0.000
M60-M63 Disorders of muscles
0.715 0.285 0.000
M00-M03 Infectious arthropathies
0.715 0.285 0.000
T42.4 Benzodiazepines
0.715 0.285 0.000
Chapter XXII Codes for special purposes
0.715 0.285 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.715 0.285 0.000
W06 Fall involving bed
0.714 0.286 0.000
S01.1 Open wound of eyelid and periocular area
0.714 0.286 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.714 0.286 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.714 0.286 0.000
M17.3 Other posttraumatic gonarthrosis
0.713 0.287 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.713 0.287 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.713 0.287 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.712 0.288 0.000
W19.2 School, other institution and public administrative area
0.712 0.288 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.712 0.288 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.712 0.288 0.000
W19.9 Unspecified place
0.711 0.289 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.711 0.289 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.711 0.289 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.711 0.289 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.710 0.290 0.000
M80 Osteoporosis with pathological fracture
0.710 0.290 0.000
R14 Flatulence and related conditions
0.708 0.291 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.708 0.292 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.707 0.293 0.000
I49 Other cardiac arrhythmias
0.707 0.293 0.000
M17.9 Gonarthrosis, unspecified
0.707 0.293 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.706 0.294 0.000
C56 Malignant neoplasm of ovary
0.706 0.294 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.705 0.295 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.705 0.295 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.705 0.295 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.705 0.295 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.705 0.295 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.705 0.295 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.705 0.295 0.000
O85-O92 Complications predominantly related to the puerperium
0.704 0.296 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.704 0.296 0.000
R19.4 Change in bowel habit
0.704 0.296 0.000
S70-S79 Injuries to the hip and thigh
0.703 0.296 0.000
I20-I25 Ischaemic heart diseases
0.703 0.297 0.000
J37 Chronic laryngitis and laryngotracheitis
0.703 0.297 0.000
R10.3 Pain localised to other parts of lower abdomen
0.703 0.297 0.000
J43 Emphysema
0.703 0.297 0.000
F99-F99 Unspecified mental disorder
0.702 0.297 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.702 0.297 0.000
F80-F89 Disorders of psychological development
0.702 0.297 0.000
F70-F79 Mental retardation
0.702 0.297 0.000
F60-F69 Disorders of adult personality and behaviour
0.702 0.297 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.702 0.297 0.000
S01.9 Open wound of head, part unspecified
0.702 0.298 0.000
N17-N19 Renal failure
0.700 0.300 0.000
I00-I02 Acute rheumatic fever
0.700 0.300 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.700 0.300 0.000
F10.3 Withdrawal state
0.698 0.302 0.000
Y83.9 Surgical procedure, unspecified
0.698 0.302 0.000
Y83.5 Amputation of limb(s)
0.698 0.302 0.000
I38 Endocarditis, valve unspecified
0.697 0.303 0.000
M13 Other arthritis
0.697 0.303 0.000
R47-R49 Symptoms and signs involving speech and voice
0.696 0.303 0.000
J40 Bronchitis, not specified as acute or chronic
0.696 0.304 0.000
G70-G73 Diseases of myoneural junction and muscle
0.696 0.304 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.696 0.304 0.000
O00-O08 Pregnancy with abortive outcome
0.695 0.305 0.000
O80-O84 Delivery
0.694 0.306 0.000
H80-H83 Diseases of inner ear
0.694 0.306 0.000
C80 Malignant neoplasm without specification of site
0.694 0.306 0.000
I52 Other heart disorders in diseases classified elsewhere
0.692 0.308 0.000
I48 Atrial fibrillation and flutter
0.692 0.308 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.692 0.308 0.000
I41 Myocarditis in diseases classified elsewhere
0.692 0.308 0.000
I40 Acute myocarditis
0.692 0.308 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.692 0.308 0.000
I37 Pulmonary valve disorders
0.692 0.308 0.000
I36 Nonrheumatic tricuspid valve disorders
0.692 0.308 0.000
I33 Acute and subacute endocarditis
0.692 0.308 0.000
I32 Pericarditis in diseases classified elsewhere
0.692 0.308 0.000
S69 Other and unspecified injuries of wrist and hand
0.692 0.308 0.000
D45 Polycythaemia vera
0.691 0.309 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.690 0.310 0.000
K76.9 Liver disease, unspecified
0.690 0.310 0.000
J41 Simple and mucopurulent chronic bronchitis
0.689 0.311 0.000
J46 Status asthmaticus
0.689 0.311 0.000
F20.0 Paranoid schizophrenia
0.689 0.311 0.000
I34 Nonrheumatic mitral valve disorders
0.688 0.311 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.688 0.312 0.000
R10.4 Other and unspecified abdominal pain
0.688 0.312 0.000
S40-S49 Injuries to the shoulder and upper arm
0.688 0.312 0.000
R73 Elevated blood glucose level
0.687 0.313 0.000
K51.8 Other ulcerative colitis
0.687 0.313 0.000
S02 Fracture of skull and facial bones
0.686 0.314 0.000
I44.1 Atrioventricular block, second degree
0.686 0.314 0.000
K77 Liver disorders in diseases classified elsewhere
0.686 0.314 0.000
K73 Chronic hepatitis, not elsewhere classified
0.686 0.314 0.000
K71 Toxic liver disease
0.686 0.314 0.000
A30-A49 Other bacterial diseases
0.685 0.315 0.000
S68 Traumatic amputation of wrist and hand
0.685 0.315 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.685 0.315 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.685 0.315 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.685 0.315 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.685 0.315 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.685 0.315 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.685 0.315 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.685 0.315 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.685 0.315 0.000
T36 Poisoning by systemic antibiotics
0.685 0.315 0.000
S52 Fracture of forearm
0.685 0.315 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.684 0.316 0.000
T78 Adverse effects, not elsewhere classified
0.684 0.316 0.000
G25 Other extrapyramidal and movement disorders
0.684 0.316 0.000
O74 Complications of anaesthesia during labour and delivery
0.683 0.316 0.000
O73 Retained placenta and membranes, without haemorrhage
0.683 0.316 0.000
O71 Other obstetric trauma
0.683 0.316 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.683 0.316 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.683 0.316 0.000
O66 Other obstructed labour
0.683 0.316 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.683 0.316 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.683 0.316 0.000
O61 Failed induction of labour
0.683 0.316 0.000
O60 Preterm delivery
0.683 0.316 0.000
H04.2 Epiphora
0.682 0.318 0.000
D46 Myelodysplastic syndromes
0.681 0.318 0.000
M25 Other joint disorders, not elsewhere classified
0.681 0.319 0.000
M10.9 Gout, unspecified
0.680 0.320 0.000
B35-B49 Mycoses
0.679 0.321 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.679 0.321 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.679 0.321 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.679 0.321 0.000
C32 Malignant neoplasm of larynx
0.679 0.321 0.000
C31 Malignant neoplasm of accessory sinuses
0.679 0.321 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.679 0.321 0.000
C37 Malignant neoplasm of thymus
0.679 0.321 0.000
C33 Malignant neoplasm of trachea
0.679 0.321 0.000
D69 Purpura and other haemorrhagic conditions
0.678 0.322 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.678 0.322 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.677 0.323 0.000
T87 Complications peculiar to reattachment and amputation
0.676 0.323 0.000
T86 Failure and rejection of transplanted organs and tissues
0.676 0.323 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.676 0.323 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.676 0.324 0.000
J33.1 Polypoid sinus degeneration
0.676 0.324 0.000
M24 Other specific joint derangements
0.675 0.324 0.000
R04.0 Epistaxis
0.675 0.325 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.675 0.325 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.675 0.325 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.675 0.325 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.675 0.325 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.675 0.325 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.675 0.325 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.675 0.325 0.000
F11 Mental and behavioural disorders due to use of opioids
0.675 0.325 0.000
S80-S89 Injuries to the knee and lower leg
0.675 0.325 0.000
S08 Traumatic amputation of part of head
0.674 0.326 0.000
S07 Crushing injury of head
0.674 0.326 0.000
S05 Injury of eye and orbit
0.674 0.326 0.000
S04 Injury of cranial nerves
0.674 0.326 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.674 0.326 0.000
K51.2 Ulcerative (chronic) proctitis
0.673 0.327 0.000
Chapter XXI Factors influencing health status and contact with health services
0.672 0.328 0.000
K76.7 Hepatorenal syndrome
0.671 0.329 0.000
K76.5 Hepatic veno-occlusive disease
0.671 0.329 0.000
K76.4 Peliosis hepatis
0.671 0.329 0.000
K76.3 Infarction of liver
0.671 0.329 0.000
K76.2 Central haemorrhagic necrosis of liver
0.671 0.329 0.000
K76.1 Chronic passive congestion of liver
0.671 0.329 0.000
K74 Fibrosis and cirrhosis of liver
0.670 0.330 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.670 0.330 0.000
J95-J99 Other diseases of the respiratory system
0.670 0.330 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.670 0.330 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.669 0.331 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.668 0.332 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.668 0.332 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.667 0.332 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.667 0.332 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.667 0.332 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.667 0.333 0.000
M23.3 Other meniscus derangements
0.666 0.334 0.000
W18 Other fall on same level
0.666 0.334 0.000
W17 Other fall from one level to another
0.666 0.334 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.666 0.334 0.000
W15 Fall from cliff
0.666 0.334 0.000
W14 Fall from tree
0.666 0.334 0.000
W13 Fall from, out of or through building or structure
0.666 0.334 0.000
W12 Fall on and from scaffolding
0.666 0.334 0.000
W11 Fall on and from ladder
0.666 0.334 0.000
W10 Fall on and from stairs and steps
0.666 0.334 0.000
W09 Fall involving playground equipment
0.666 0.334 0.000
W07 Fall involving chair
0.666 0.334 0.000
W05 Fall involving wheelchair
0.666 0.334 0.000
W04 Fall while being carried or supported by other persons
0.666 0.334 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.666 0.334 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.666 0.334 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.666 0.334 0.000
W00 Fall on same level involving ice and snow
0.666 0.334 0.000
M53 Other dorsopathies, not elsewhere classified
0.665 0.335 0.000
R19.6 Halitosis
0.665 0.335 0.000
R19.3 Abdominal rigidity
0.665 0.335 0.000
R19.2 Visible peristalsis
0.665 0.335 0.000
R19.1 Abnormal bowel sounds
0.665 0.335 0.000
T90 Sequelae of injuries of head
0.665 0.335 0.000
R10.0 Acute abdomen
0.664 0.336 0.000
T93 Sequelae of injuries of lower limb
0.663 0.337 0.000
K51.5 Mucosal proctocolitis
0.663 0.337 0.000
K51.4 Pseudopolyposis of colon
0.663 0.337 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.663 0.337 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.663 0.337 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.663 0.337 0.000
O70.9 Perineal laceration during delivery, unspecified
0.663 0.337 0.000
O70.3 Fourth degree perineal laceration during delivery
0.663 0.337 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.662 0.338 0.000
G96 Other disorders of central nervous system
0.662 0.338 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.662 0.338 0.000
G90 Disorders of autonomic nervous system
0.662 0.338 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.662 0.338 0.000
G92 Toxic encephalopathy
0.662 0.338 0.000
O72 Postpartum haemorrhage
0.662 0.338 0.000
K70 Alcoholic liver disease
0.661 0.339 0.000
K76.6 Portal hypertension
0.661 0.339 0.000
C34.8 Overlapping lesion of bronchus and lung
0.660 0.339 0.000
C34.2 Middle lobe, bronchus or lung
0.660 0.339 0.000
C34.0 Main bronchus
0.660 0.339 0.000
I44.6 Other and unspecified fascicular block
0.660 0.340 0.000
I44.5 Left posterior fascicular block
0.660 0.340 0.000
I44.4 Left anterior fascicular block
0.660 0.340 0.000
I44.3 Other and unspecified atrioventricular block
0.660 0.340 0.000
I69 Sequelae of cerebrovascular disease
0.660 0.340 0.000
K72.9 Hepatic failure, unspecified
0.660 0.340 0.000
S61.0 Open wound of finger(s) without damage to nail
0.659 0.341 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.659 0.341 0.000
M34 Systemic sclerosis
0.659 0.341 0.000
M33 Dermatopolymyositis
0.659 0.341 0.000
M32 Systemic lupus erythematosus
0.659 0.341 0.000
M30 Polyarteritis nodosa and related conditions
0.659 0.341 0.000
M22 Disorders of patella
0.659 0.341 0.000
M21 Other acquired deformities of limbs
0.659 0.341 0.000
R29.6 Tendency to fall, not elsewhere classified
0.659 0.341 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.658 0.342 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.658 0.342 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.658 0.342 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.658 0.342 0.000
M54.2 Cervicalgia
0.658 0.342 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.658 0.342 0.000
W29 Contact with other powered hand tools and household machinery
0.657 0.343 0.000
R06 Abnormalities of breathing
0.656 0.344 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.656 0.344 0.000
E00-E07 Disorders of thyroid gland
0.655 0.345 0.000
R25 Abnormal involuntary movements
0.655 0.345 0.000
E40-E46 Malnutrition
0.655 0.345 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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