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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75352895
log Bayes Factor = 11.4763
Chromosome 2   position 126,970,097  (GRCh37) Explore rs75352895 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
I63 Cerebral infarction
0.999 0.001 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.997 0.003 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.994 0.006 0.000
D69 Purpura and other haemorrhagic conditions
0.992 0.008 0.000
I69 Sequelae of cerebrovascular disease
0.990 0.010 0.000
Chapter XX External causes of morbidity and mortality
0.981 0.019 0.000
Chapter X Diseases of the respiratory system
0.979 0.021 0.000
K70-K77 Diseases of liver
0.977 0.023 0.000
D69.6 Thrombocytopenia, unspecified
0.976 0.024 0.000
I63.9 Cerebral infarction, unspecified
0.973 0.027 0.000
Chapter XI Diseases of the digestive system
0.972 0.028 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.972 0.028 0.000
K70 Alcoholic liver disease
0.971 0.029 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.966 0.034 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.966 0.034 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.964 0.036 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.964 0.036 0.000
S00-S09 Injuries to the head
0.962 0.038 0.000
J09-J18 Influenza and pneumonia
0.961 0.039 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.946 0.054 0.000
S01 Open wound of head
0.942 0.058 0.000
H55-H59 Other disorders of eye and adnexa
0.923 0.077 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.923 0.077 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.923 0.077 0.000
K74 Fibrosis and cirrhosis of liver
0.920 0.080 0.000
S01.1 Open wound of eyelid and periocular area
0.919 0.081 0.000
K76 Other diseases of liver
0.919 0.081 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.919 0.081 0.000
K70.9 Alcoholic liver disease, unspecified
0.919 0.081 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.918 0.082 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.918 0.082 0.000
J18 Pneumonia, organism unspecified
0.909 0.091 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.907 0.093 0.000
Chapter II Neoplasms
0.900 0.100 0.000
H20 Iridocyclitis
0.893 0.107 0.000
S60-S69 Injuries to the wrist and hand
0.891 0.109 0.000
Y43 Primarily systemic agents
0.891 0.109 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.888 0.112 0.000
H30-H36 Disorders of choroid and retina
0.887 0.113 0.000
S32 Fracture of lumbar spine and pelvis
0.885 0.115 0.000
I71 Aortic aneurysm and dissection
0.885 0.115 0.000
I67 Other cerebrovascular diseases
0.882 0.118 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.878 0.122 0.000
Chapter VI Diseases of the nervous system
0.873 0.127 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.871 0.129 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.866 0.134 0.000
S62 Fracture at wrist and hand level
0.866 0.134 0.000
K70.1 Alcoholic hepatitis
0.865 0.135 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.863 0.137 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.862 0.138 0.000
J40-J47 Chronic lower respiratory diseases
0.855 0.145 0.000
I69.3 Sequelae of cerebral infarction
0.854 0.146 0.000
K83 Other diseases of biliary tract
0.854 0.146 0.000
K76.8 Other specified diseases of liver
0.852 0.148 0.000
K75 Other inflammatory liver diseases
0.850 0.150 0.000
Q50-Q56 Congenital malformations of genital organs
0.849 0.151 0.000
K70.3 Alcoholic cirrhosis of liver
0.848 0.152 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.846 0.154 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.844 0.156 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.839 0.161 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.835 0.165 0.000
H59.8 Other postprocedural disorders of eye and adnexa
0.834 0.166 0.000
X60-X84 Intentional self-harm
0.829 0.171 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.829 0.171 0.000
K70.4 Alcoholic hepatic failure
0.828 0.172 0.000
H20.9 Iridocyclitis, unspecified
0.828 0.172 0.000
T92 Sequelae of injuries of upper limb
0.826 0.174 0.000
S10-S19 Injuries to the neck
0.825 0.175 0.000
J20-J22 Other acute lower respiratory infections
0.824 0.176 0.000
H21 Other disorders of iris and ciliary body
0.824 0.176 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.824 0.176 0.000
J18.0 Bronchopneumonia, unspecified
0.823 0.177 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.823 0.177 0.000
Y43.3 Other antineoplastic drugs
0.818 0.182 0.000
H35 Other retinal disorders
0.817 0.183 0.000
Chapter I Certain infectious and parasitic diseases
0.816 0.184 0.000
K83.0 Cholangitis
0.815 0.185 0.000
S01.9 Open wound of head, part unspecified
0.815 0.185 0.000
K74.3 Primary biliary cirrhosis
0.814 0.186 0.000
M70-M79 Other soft tissue disorders
0.814 0.186 0.000
H53-H54 Visual disturbances and blindness
0.814 0.186 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.813 0.187 0.000
K86 Other diseases of pancreas
0.812 0.188 0.000
Y57 Other and unspecified drugs and medicaments
0.812 0.188 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.810 0.189 0.000
W20-W49 Exposure to inanimate mechanical forces
0.807 0.193 0.000
G81 Hemiplegia
0.807 0.193 0.000
S62.6 Fracture of other finger
0.807 0.193 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.802 0.198 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.801 0.199 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.798 0.202 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.795 0.205 0.000
C15-C26 Malignant neoplasms of digestive organs
0.793 0.207 0.000
T79-T79 Certain early complications of trauma
0.793 0.207 0.000
D37.4 Colon
0.792 0.208 0.000
D75 Other diseases of blood and blood-forming organs
0.792 0.208 0.000
Y44 Agents primarily affecting blood constituents
0.791 0.209 0.000
H52 Disorders of refraction and accommodation
0.790 0.210 0.000
I80 Phlebitis and thrombophlebitis
0.790 0.210 0.000
I85 Oesophageal varices
0.789 0.211 0.000
G81.9 Hemiplegia, unspecified
0.787 0.213 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.786 0.214 0.000
S32.4 Fracture of acetabulum
0.785 0.215 0.000
Chapter XXII Codes for special purposes
0.784 0.216 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.783 0.217 0.000
J95-J99 Other diseases of the respiratory system
0.782 0.218 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.781 0.219 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.777 0.222 0.000
I78 Diseases of capillaries
0.777 0.223 0.000
S05 Injury of eye and orbit
0.776 0.224 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.776 0.224 0.000
I67.9 Cerebrovascular disease, unspecified
0.774 0.226 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.773 0.227 0.000
S80-S89 Injuries to the knee and lower leg
0.773 0.227 0.000
B35-B49 Mycoses
0.773 0.227 0.000
H25-H28 Disorders of lens
0.773 0.227 0.000
J18.1 Lobar pneumonia, unspecified
0.771 0.229 0.000
D69.0 Allergic purpura
0.770 0.230 0.000
K65-K67 Diseases of peritoneum
0.770 0.230 0.000
S70-S79 Injuries to the hip and thigh
0.769 0.231 0.000
J14 Pneumonia due to Haemophilus influenzae
0.769 0.231 0.000
K74.6 Other and unspecified cirrhosis of liver
0.768 0.232 0.000
S01.0 Open wound of scalp
0.761 0.239 0.000
K74.5 Biliary cirrhosis, unspecified
0.760 0.240 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.758 0.242 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.758 0.242 0.000
K75.8 Other specified inflammatory liver diseases
0.758 0.242 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.757 0.243 0.000
I61 Intracerebral haemorrhage
0.757 0.243 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.756 0.244 0.000
D50-D53 Nutritional anaemias
0.755 0.245 0.000
M75 Shoulder lesions
0.755 0.245 0.000
Q80-Q89 Other congenital malformations
0.751 0.248 0.000
K76.9 Liver disease, unspecified
0.751 0.249 0.000
D37.7 Other digestive organs
0.751 0.249 0.000
J11 Influenza, virus not identified
0.750 0.250 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.750 0.250 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.750 0.250 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.749 0.251 0.000
G30-G32 Other degenerative diseases of the nervous system
0.749 0.251 0.000
S62.60 Fracture of other finger (closed)
0.749 0.251 0.000
H34 Retinal vascular occlusions
0.748 0.252 0.000
I63.8 Other cerebral infarction
0.748 0.252 0.000
V40-V49 Car occupant injured in transport accident
0.748 0.252 0.000
K83.1 Obstruction of bile duct
0.743 0.257 0.000
S32.0 Fracture of lumbar vertebra
0.742 0.257 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.742 0.258 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.740 0.260 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.739 0.261 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.738 0.262 0.000
J60-J70 Lung diseases due to external agents
0.738 0.262 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.737 0.263 0.000
J45 Asthma
0.737 0.263 0.000
S62.3 Fracture of other metacarpal bone
0.737 0.263 0.000
X20-X29 Contact with venomous animals and plants
0.736 0.264 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.736 0.264 0.000
D70 Agranulocytosis
0.736 0.264 0.000
S32.5 Fracture of pubis
0.735 0.265 0.000
K86.9 Disease of pancreas, unspecified
0.735 0.265 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.734 0.266 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.734 0.266 0.000
D72 Other disorders of white blood cells
0.733 0.267 0.000
J22 Unspecified acute lower respiratory infection
0.733 0.267 0.000
W50-W64 Exposure to animate mechanical forces
0.732 0.268 0.000
K83.8 Other specified diseases of biliary tract
0.731 0.269 0.000
K90-K93 Other diseases of the digestive system
0.731 0.269 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.729 0.271 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.728 0.272 0.000
I85.9 Oesophageal varices without bleeding
0.728 0.272 0.000
T93 Sequelae of injuries of lower limb
0.728 0.272 0.000
I62 Other nontraumatic intracranial haemorrhage
0.727 0.273 0.000
K76.7 Hepatorenal syndrome
0.727 0.273 0.000
S01.7 Multiple open wounds of head
0.725 0.275 0.000
H20.1 Chronic iridocyclitis
0.724 0.276 0.000
K76.6 Portal hypertension
0.723 0.277 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.723 0.277 0.000
J44 Other chronic obstructive pulmonary disease
0.723 0.277 0.000
B37 Candidiasis
0.723 0.277 0.000
H52.1 Myopia
0.722 0.278 0.000
J46 Status asthmaticus
0.722 0.278 0.000
Chapter VIII Diseases of the ear and mastoid process
0.721 0.279 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.718 0.281 0.000
Y52 Agents primarily affecting the cardiovascular system
0.718 0.282 0.000
M75.5 Bursitis of shoulder
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.717 0.283 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
C16 Malignant neoplasm of stomach
0.716 0.284 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.716 0.284 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.716 0.284 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.716 0.284 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.716 0.284 0.000
D55-D59 Haemolytic anaemias
0.716 0.284 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.715 0.285 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.715 0.285 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.715 0.285 0.000
H27 Other disorders of lens
0.714 0.286 0.000
J45.0 Predominantly allergic asthma
0.713 0.287 0.000
T91 Sequelae of injuries of neck and trunk
0.713 0.287 0.000
S32.40 Fracture of acetabulum (closed)
0.713 0.287 0.000
S00 Superficial injury of head
0.713 0.287 0.000
D67 Hereditary factor IX deficiency
0.713 0.287 0.000
D66 Hereditary factor VIII deficiency
0.713 0.287 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.713 0.287 0.000
V20-V29 Motorcycle rider injured in transport accident
0.712 0.288 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.712 0.288 0.000
D69.9 Haemorrhagic condition, unspecified
0.712 0.288 0.000
D69.8 Other specified haemorrhagic conditions
0.712 0.288 0.000
D69.5 Secondary thrombocytopenia
0.712 0.288 0.000
D69.4 Other primary thrombocytopenia
0.712 0.288 0.000
D69.2 Other nonthrombocytopenic purpura
0.712 0.288 0.000
D69.1 Qualitative platelet defects
0.712 0.288 0.000
X50-X57 Overexertion, travel and privation
0.711 0.288 0.000
S90-S99 Injuries to the ankle and foot
0.711 0.289 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.710 0.289 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.710 0.290 0.000
I26 Pulmonary embolism
0.710 0.290 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.710 0.290 0.000
H21.8 Other specified disorders of iris and ciliary body
0.709 0.291 0.000
S09 Other and unspecified injuries of head
0.709 0.291 0.000
Y43.1 Antineoplastic antimetabolites
0.709 0.291 0.000
M75.3 Calcific tendinitis of shoulder
0.709 0.291 0.000
S40-S49 Injuries to the shoulder and upper arm
0.709 0.291 0.000
S01.8 Open wound of other parts of head
0.709 0.291 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.708 0.292 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.707 0.293 0.000
I67.2 Cerebral atherosclerosis
0.706 0.294 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.704 0.296 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.704 0.296 0.000
Q60-Q64 Congenital malformations of the urinary system
0.704 0.296 0.000
S62.5 Fracture of thumb
0.703 0.297 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.703 0.297 0.000
Y35-Y36 Legal intervention and operations of war
0.703 0.297 0.000
Y10-Y34 Event of undetermined intent
0.703 0.297 0.000
Y00-Y09 Assault
0.703 0.297 0.000
X85-X99 Assault
0.703 0.297 0.000
X30-X39 Exposure to forces of nature
0.703 0.297 0.000
X10-X19 Contact with heat and hot substances
0.703 0.297 0.000
X00-X09 Exposure to smoke, fire and flames
0.703 0.297 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.703 0.297 0.000
W75-W84 Other accidental threats to breathing
0.703 0.297 0.000
W65-W74 Accidental drowning and submersion
0.703 0.297 0.000
V98-V99 Other and unspecified transport accidents
0.703 0.297 0.000
V95-V97 Air and space transport accidents
0.703 0.297 0.000
V90-V94 Water transport accidents
0.703 0.297 0.000
V70-V79 Bus occupant injured in transport accident
0.703 0.297 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.703 0.297 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.703 0.297 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.703 0.297 0.000
V01-V09 Pedestrian injured in transport accident
0.703 0.297 0.000
I74 Arterial embolism and thrombosis
0.702 0.298 0.000
J18.9 Pneumonia, unspecified
0.702 0.298 0.000
K77 Liver disorders in diseases classified elsewhere
0.701 0.299 0.000
K73 Chronic hepatitis, not elsewhere classified
0.701 0.299 0.000
K71 Toxic liver disease
0.701 0.299 0.000
H49 Paralytic strabismus
0.700 0.300 0.000
D00-D09 In situ neoplasms
0.698 0.302 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.698 0.302 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.697 0.303 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.696 0.304 0.000
K70.0 Alcoholic fatty liver
0.696 0.304 0.000
T23 Burn and corrosion of wrist and hand
0.696 0.304 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.695 0.305 0.000
H35.8 Other specified retinal disorders
0.694 0.306 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.693 0.307 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.693 0.307 0.000
Q35-Q37 Cleft lip and cleft palate
0.693 0.307 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.693 0.307 0.000
H05 Disorders of orbit
0.692 0.308 0.000
M80-M85 Disorders of bone density and structure
0.691 0.309 0.000
Y59 Other and unspecified vaccines and biological substances
0.691 0.309 0.000
Y58 Bacterial vaccines
0.691 0.309 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.691 0.309 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.691 0.309 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.691 0.309 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.691 0.309 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.691 0.309 0.000
Y48 Anaesthetics and therapeutic gases
0.691 0.309 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.691 0.309 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.691 0.309 0.000
M86-M90 Other osteopathies
0.690 0.310 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.690 0.310 0.000
S08 Traumatic amputation of part of head
0.690 0.310 0.000
S07 Crushing injury of head
0.690 0.310 0.000
S04 Injury of cranial nerves
0.690 0.310 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.690 0.310 0.000
Q65 Congenital deformities of hip
0.689 0.311 0.000
J17 Pneumonia in diseases classified elsewhere
0.689 0.311 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.689 0.311 0.000
J12 Viral pneumonia, not elsewhere classified
0.689 0.311 0.000
J09 Influenza due to certain identified influenza virus
0.689 0.311 0.000
D46 Myelodysplastic syndromes
0.688 0.312 0.000
C64-C68 Malignant neoplasms of urinary tract
0.688 0.312 0.000
H55 Nystagmus and other irregular eye movements
0.688 0.312 0.000
S69 Other and unspecified injuries of wrist and hand
0.688 0.312 0.000
D80-D89 Certain disorders involving the immune mechanism
0.686 0.314 0.000
B95-B98 Bacterial, viral and other infectious agents
0.685 0.315 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.684 0.316 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.684 0.316 0.000
J10 Influenza due to identified influenza virus
0.683 0.317 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.681 0.319 0.000
Y85 Sequelae of transport accidents
0.681 0.319 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.680 0.319 0.000
D37.6 Liver, gallbladder and bile ducts
0.680 0.320 0.000
D73 Diseases of spleen
0.680 0.320 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.679 0.320 0.000
J81 Pulmonary oedema
0.679 0.321 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.678 0.321 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.678 0.321 0.000
H17 Corneal scars and opacities
0.678 0.321 0.000
H15 Disorders of sclera
0.678 0.321 0.000
S62.4 Multiple fractures of metacarpal bones
0.678 0.322 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.678 0.322 0.000
Y86 Sequelae of other accidents
0.677 0.323 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.677 0.323 0.000
S20-S29 Injuries to the thorax
0.676 0.323 0.000
K86.8 Other specified diseases of pancreas
0.676 0.324 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.676 0.324 0.000
H20.0 Acute and subacute iridocyclitis
0.675 0.325 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.674 0.326 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.674 0.326 0.000
M79.1 Myalgia
0.674 0.326 0.000
G90-G99 Other disorders of the nervous system
0.674 0.326 0.000
Y57.8 Other drugs and medicaments
0.673 0.327 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.672 0.328 0.000
H35.2 Other proliferative retinopathy
0.672 0.328 0.000
H35.0 Background retinopathy and retinal vascular changes
0.672 0.328 0.000
H10-H13 Disorders of conjunctiva
0.671 0.329 0.000
H53 Visual disturbances
0.671 0.329 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.671 0.329 0.000
T42.4 Benzodiazepines
0.670 0.330 0.000
H65-H75 Diseases of middle ear and mastoid
0.670 0.330 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.669 0.331 0.000
Q51 Congenital malformations of uterus and cervix
0.669 0.331 0.000
D37.2 Small intestine
0.669 0.331 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.668 0.332 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.668 0.332 0.000
I67.8 Other specified cerebrovascular diseases
0.667 0.333 0.000
Y44.2 Anticoagulants
0.667 0.333 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.667 0.333 0.000
K75.9 Inflammatory liver disease, unspecified
0.666 0.333 0.000
I70 Atherosclerosis
0.666 0.334 0.000
V80-V89 Other land transport accidents
0.665 0.334 0.000
Y45.5 4-Aminophenol derivatives
0.665 0.335 0.000
H01 Other inflammation of eyelid
0.664 0.336 0.000
G83 Other paralytic syndromes
0.664 0.336 0.000
D75.2 Essential thrombocytosis
0.664 0.336 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.662 0.338 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.662 0.338 0.000
S37 Injury of urinary and pelvic organs
0.662 0.338 0.000
S36 Injury of intra-abdominal organs
0.662 0.338 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.662 0.338 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.662 0.338 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.662 0.338 0.000
S31 Open wound of abdomen, lower back and pelvis
0.662 0.338 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.661 0.338 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.661 0.339 0.000
K74.4 Secondary biliary cirrhosis
0.660 0.340 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.660 0.340 0.000
K74.1 Hepatic sclerosis
0.660 0.340 0.000
K76.5 Hepatic veno-occlusive disease
0.659 0.341 0.000
K76.4 Peliosis hepatis
0.659 0.341 0.000
K76.3 Infarction of liver
0.659 0.341 0.000
K76.2 Central haemorrhagic necrosis of liver
0.659 0.341 0.000
K76.1 Chronic passive congestion of liver
0.659 0.341 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.658 0.342 0.000
D74 Methaemoglobinaemia
0.658 0.342 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.658 0.342 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.658 0.342 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.658 0.342 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.658 0.342 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.658 0.342 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.658 0.342 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.658 0.342 0.000
T36 Poisoning by systemic antibiotics
0.658 0.342 0.000
Y40 Systemic antibiotics
0.658 0.342 0.000
M79.0 Rheumatism, unspecified
0.658 0.342 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.656 0.343 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.656 0.344 0.000
Q00-Q07 Congenital malformations of the nervous system
0.656 0.344 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.655 0.345 0.000
I81 Portal vein thrombosis
0.655 0.345 0.000
Q53 Undescended testicle
0.655 0.345 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.655 0.345 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.654 0.346 0.000
S01.2 Open wound of nose
0.654 0.346 0.000
C16.0 Cardia
0.653 0.347 0.000
M40-M43 Deforming dorsopathies
0.653 0.347 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.653 0.347 0.000
H27.0 Aphakia
0.653 0.347 0.000
S32.1 Fracture of sacrum
0.652 0.348 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.652 0.348 0.000
J18.8 Other pneumonia, organism unspecified
0.652 0.348 0.000
J18.2 Hypostatic pneumonia, unspecified
0.652 0.348 0.000
Y45.8 Other analgesics and antipyretics
0.651 0.349 0.000
T95 Sequelae of burns, corrosions and frostbite
0.651 0.349 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.651 0.349 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.651 0.349 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.648 0.352 0.000
D51 Vitamin B12 deficiency anaemia
0.648 0.352 0.000
S50-S59 Injuries to the elbow and forearm
0.647 0.353 0.000
K86.3 Pseudocyst of pancreas
0.647 0.353 0.000
T98 Sequelae of other and unspecified effects of external causes
0.647 0.353 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.647 0.353 0.000
R50-R69 General symptoms and signs
0.647 0.353 0.000
M79.7 Fibromyalgia
0.646 0.354 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.646 0.354 0.000
H21.5 Other adhesions and disruptions of iris and ciliary body
0.646 0.354 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.645 0.355 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.645 0.355 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.645 0.355 0.000
S62.30 Fracture of other metacarpal bone (closed)
0.644 0.356 0.000
S06 Intracranial injury
0.644 0.356 0.000
J40 Bronchitis, not specified as acute or chronic
0.644 0.356 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.642 0.358 0.000
H20.8 Other iridocyclitis
0.641 0.359 0.000
H20.2 Lens-induced iridocyclitis
0.641 0.359 0.000
D60-D64 Aplastic and other anaemias
0.640 0.360 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.640 0.360 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.640 0.360 0.000
S62.61 Fracture of other finger (open)
0.639 0.361 0.000
I78.1 Naevus, nonneoplastic
0.639 0.361 0.000
S65 Injury of blood vessels at wrist and hand level
0.639 0.361 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.639 0.361 0.000
K74.0 Hepatic fibrosis
0.639 0.361 0.000
H35.5 Hereditary retinal dystrophy
0.639 0.361 0.000
Y43.9 Primarily systemic agent, unspecified
0.638 0.361 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.638 0.361 0.000
Y43.6 Enzymes, not elsewhere classified
0.638 0.361 0.000
Y43.5 Acidifying and alkalising agents
0.638 0.361 0.000
Y43.4 Immunosuppressive agents
0.638 0.361 0.000
Y43.2 Antineoplastic natural products
0.638 0.361 0.000
Y43.0 Antiallergic and antiemetic drugs
0.638 0.361 0.000
H18 Other disorders of cornea
0.638 0.361 0.000
Q18 Other congenital malformations of face and neck
0.638 0.362 0.000
J98 Other respiratory disorders
0.638 0.362 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.638 0.362 0.000
M60-M63 Disorders of muscles
0.637 0.363 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.637 0.363 0.000
H53.1 Subjective visual disturbances
0.637 0.363 0.000
C20 Malignant neoplasm of rectum
0.637 0.363 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.636 0.363 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.636 0.363 0.000
W22 Striking against or struck by other objects
0.636 0.364 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.636 0.364 0.000
H31 Other disorders of choroid
0.636 0.364 0.000
H30 Chorioretinal inflammation
0.636 0.364 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.634 0.365 0.000
S32.3 Fracture of ilium
0.634 0.365 0.000
S32.2 Fracture of coccyx
0.634 0.365 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.634 0.366 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.634 0.366 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.634 0.366 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.634 0.366 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.634 0.366 0.000
I71.0 Dissection of aorta [any part]
0.634 0.366 0.000
S05.8 Other injuries of eye and orbit
0.634 0.366 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.634 0.366 0.000
C01 Malignant neoplasm of base of tongue
0.633 0.367 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.633 0.367 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.632 0.368 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.632 0.368 0.000
I67.5 Moyamoya disease
0.632 0.368 0.000
I67.4 Hypertensive encephalopathy
0.632 0.368 0.000
I67.3 Progressive vascular leukoencephalopathy
0.632 0.368 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.632 0.368 0.000
Y89 Sequelae of other external causes
0.632 0.368 0.000
I73 Other peripheral vascular diseases
0.632 0.368 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.632 0.368 0.000
M91-M94 Chondropathies
0.631 0.369 0.000
Y57.9 Drug or medicament, unspecified
0.631 0.369 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.631 0.369 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.630 0.370 0.000
H51 Other disorders of binocular movement
0.630 0.370 0.000
D39.1 Ovary
0.630 0.370 0.000
D72.1 Eosinophilia
0.629 0.371 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.629 0.371 0.000
B37.8 Candidiasis of other sites
0.629 0.371 0.000
M65-M68 Disorders of synovium and tendon
0.628 0.372 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.628 0.372 0.000
B49 Unspecified mycosis
0.627 0.373 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.627 0.373 0.000
H57 Other disorders of eye and adnexa
0.627 0.373 0.000
S32.50 Fracture of pubis (closed)
0.627 0.373 0.000
H35.6 Retinal haemorrhage
0.626 0.374 0.000
M45-M49 Spondylopathies
0.626 0.374 0.000
I72 Other aneurysm
0.626 0.374 0.000
W44 Foreign body entering into or through eye or natural orifice
0.626 0.374 0.000
D75.1 Secondary polycythaemia
0.625 0.375 0.000
Y45.2 Propionic acid derivatives
0.625 0.375 0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified
0.625 0.375 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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