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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75583295
log Bayes Factor = 19.5736
Chromosome 8   position 63,596,650  (GRCh37) Explore rs75583295 on Ensembl!
Variant rs75583295 is part of Cluster X0071

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
N17-N19 Renal failure
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.997 0.003 0.000
N40-N51 Diseases of male genital organs
0.995 0.005 0.000
Chapter X Diseases of the respiratory system
0.995 0.005 0.000
M23 Internal derangement of knee
0.995 0.005 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.994 0.006 0.000
Chapter XXI Factors influencing health status and contact with health services
0.993 0.007 0.000
N18 Chronic renal failure
0.993 0.007 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.992 0.008 0.000
H25-H28 Disorders of lens
0.990 0.010 0.000
M15-M19 Arthrosis
0.989 0.011 0.000
E10-E14 Diabetes mellitus
0.989 0.011 0.000
Chapter XX External causes of morbidity and mortality
0.988 0.012 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.987 0.013 0.000
R50-R69 General symptoms and signs
0.987 0.013 0.000
H25 Senile cataract
0.986 0.014 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.985 0.015 0.000
R63 Symptoms and signs concerning food and fluid intake
0.984 0.016 0.000
M05-M14 Inflammatory polyarthropathies
0.982 0.018 0.000
N48 Other disorders of penis
0.981 0.019 0.000
M45-M49 Spondylopathies
0.978 0.022 0.000
M19 Other arthrosis
0.977 0.023 0.000
R63.4 Abnormal weight loss
0.977 0.023 0.000
M50-M54 Other dorsopathies
0.976 0.024 0.000
J09-J18 Influenza and pneumonia
0.974 0.026 0.000
N18.9 Chronic renal failure, unspecified
0.973 0.027 0.000
N19 Unspecified renal failure
0.971 0.029 0.000
J95-J99 Other diseases of the respiratory system
0.970 0.030 0.000
E10 Insulin-dependent diabetes mellitus
0.963 0.037 0.000
G90-G99 Other disorders of the nervous system
0.961 0.039 0.000
E11 Non-insulin-dependent diabetes mellitus
0.957 0.043 0.000
M06 Other rheumatoid arthritis
0.956 0.044 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.955 0.045 0.000
J18 Pneumonia, organism unspecified
0.955 0.045 0.000
M19.9 Arthrosis, unspecified
0.950 0.050 0.000
J18.9 Pneumonia, unspecified
0.948 0.052 0.000
H25.1 Senile nuclear cataract
0.947 0.053 0.000
Z51 Other medical care
0.946 0.054 0.000
N50 Other disorders of male genital organs
0.944 0.056 0.000
Z50 Care involving use of rehabilitation procedures
0.943 0.057 0.000
J98 Other respiratory disorders
0.933 0.067 0.000
M17 Gonarthrosis [arthrosis of knee]
0.928 0.072 0.000
M06.9 Rheumatoid arthritis, unspecified
0.928 0.072 0.000
M51 Other intervertebral disk disorders
0.925 0.075 0.000
H25.0 Senile incipient cataract
0.925 0.075 0.000
M47 Spondylosis
0.921 0.079 0.000
M21 Other acquired deformities of limbs
0.921 0.079 0.000
R59 Enlarged lymph nodes
0.919 0.081 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.919 0.081 0.000
Z43 Attention to artificial openings
0.912 0.088 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.908 0.092 0.000
M48 Other spondylopathies
0.899 0.101 0.000
N00-N08 Glomerular diseases
0.899 0.101 0.000
R69 Unknown and unspecified causes of morbidity
0.895 0.105 0.000
Chapter V Mental and behavioural disorders
0.895 0.105 0.000
N48.6 Balanitis xerotica obliterans
0.895 0.105 0.000
H25.8 Other senile cataract
0.895 0.105 0.000
N48.0 Leukoplakia of penis
0.890 0.110 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.889 0.111 0.000
M19.0 Primary arthrosis of other joints
0.889 0.111 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.888 0.112 0.000
M54 Dorsalgia
0.887 0.113 0.000
J98.4 Other disorders of lung
0.886 0.114 0.000
E10.3 With ophthalmic complications
0.885 0.115 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.884 0.116 0.000
Z51.5 Palliative care
0.882 0.118 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.881 0.119 0.000
M25 Other joint disorders, not elsewhere classified
0.881 0.119 0.000
Z43.2 Attention to ileostomy
0.877 0.123 0.000
M17.9 Gonarthrosis, unspecified
0.875 0.125 0.000
R63.0 Anorexia
0.875 0.125 0.000
Z51.0 Radiotherapy session
0.874 0.126 0.000
N30-N39 Other diseases of urinary system
0.872 0.128 0.000
M19.94 Arthrosis, unspecified (Hand)
0.870 0.130 0.000
R59.0 Localised enlarged lymph nodes
0.870 0.130 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.869 0.131 0.000
Chapter VIII Diseases of the ear and mastoid process
0.868 0.132 0.000
R51 Headache
0.868 0.132 0.000
M47.9 Spondylosis, unspecified
0.865 0.135 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.863 0.137 0.000
Z54 Convalescence
0.861 0.139 0.000
H55-H59 Other disorders of eye and adnexa
0.860 0.140 0.000
N18.5 Chronic kidney disease, stage 5
0.855 0.145 0.000
M24 Other specific joint derangements
0.855 0.145 0.000
E10.9 Without complications
0.855 0.145 0.000
G95 Other diseases of spinal cord
0.852 0.148 0.000
H27 Other disorders of lens
0.852 0.148 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.852 0.148 0.000
Z45 Adjustment and management of implanted device
0.850 0.150 0.000
M51.8 Other specified intervertebral disk disorders
0.850 0.150 0.000
M80-M85 Disorders of bone density and structure
0.849 0.151 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.848 0.152 0.000
H40-H42 Glaucoma
0.845 0.155 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.845 0.155 0.000
N18.4 Chronic kidney disease, stage 4
0.844 0.156 0.000
E11.4 With neurological complications
0.844 0.156 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.841 0.159 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.839 0.161 0.000
R63.1 Polydipsia
0.836 0.164 0.000
J40-J47 Chronic lower respiratory diseases
0.835 0.165 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.835 0.165 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.835 0.165 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.834 0.166 0.000
H53-H54 Visual disturbances and blindness
0.833 0.167 0.000
M48.0 Spinal stenosis
0.832 0.168 0.000
M05 Seropositive rheumatoid arthritis
0.832 0.168 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.828 0.172 0.000
N50.1 Vascular disorders of male genital organs
0.825 0.175 0.000
M21.3 Wrist or foot drop (acquired)
0.825 0.175 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.825 0.175 0.000
N50.8 Other specified disorders of male genital organs
0.825 0.175 0.000
V10-V19 Pedal cyclist injured in transport accident
0.824 0.176 0.000
W00-W19 Falls
0.824 0.176 0.000
Z50.5 Speech therapy
0.818 0.182 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.813 0.186 0.000
N30 Cystitis
0.813 0.187 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.812 0.188 0.000
G35 Multiple sclerosis
0.810 0.190 0.000
R30-R39 Symptoms and signs involving the urinary system
0.810 0.190 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.808 0.192 0.000
Z48 Other surgical follow-up care
0.807 0.192 0.000
S00-S09 Injuries to the head
0.807 0.193 0.000
N35 Urethral stricture
0.806 0.194 0.000
N42 Other disorders of prostate
0.801 0.199 0.000
F30-F39 Mood [affective] disorders
0.799 0.201 0.000
N48.1 Balanoposthitis
0.799 0.201 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.799 0.201 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.798 0.201 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.797 0.203 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.797 0.203 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.796 0.204 0.000
N18.3 Chronic kidney disease, stage 3
0.795 0.205 0.000
N48.2 Other inflammatory disorders of penis
0.795 0.205 0.000
M86-M90 Other osteopathies
0.794 0.206 0.000
R21 Rash and other nonspecific skin eruption
0.794 0.206 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.793 0.207 0.000
M23.3 Other meniscus derangements
0.792 0.208 0.000
M22 Disorders of patella
0.792 0.208 0.000
H30-H36 Disorders of choroid and retina
0.791 0.209 0.000
Z50.0 Cardiac rehabilitation
0.789 0.211 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.789 0.211 0.000
Z36 Antenatal screening
0.788 0.212 0.000
G40-G47 Episodic and paroxysmal disorders
0.788 0.212 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.788 0.212 0.000
E11.3 With ophthalmic complications
0.787 0.213 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.785 0.215 0.000
E20-E35 Disorders of other endocrine glands
0.785 0.215 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.784 0.216 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.784 0.216 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.784 0.216 0.000
M23.5 Chronic instability of knee
0.783 0.217 0.000
E10.2 With renal complications
0.782 0.218 0.000
Chapter XXII Codes for special purposes
0.781 0.219 0.000
V80-V89 Other land transport accidents
0.779 0.221 0.000
N30.2 Other chronic cystitis
0.779 0.221 0.000
E70-E90 Metabolic disorders
0.779 0.221 0.000
M06.0 Seronegative rheumatoid arthritis
0.778 0.222 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.777 0.223 0.000
N48.8 Other specified disorders of penis
0.775 0.225 0.000
J60-J70 Lung diseases due to external agents
0.774 0.226 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.772 0.228 0.000
G90 Disorders of autonomic nervous system
0.772 0.228 0.000
H52 Disorders of refraction and accommodation
0.771 0.228 0.000
R35 Polyuria
0.771 0.229 0.000
Z54.0 Convalescence following surgery
0.771 0.229 0.000
E11.1 With ketoacidosis
0.770 0.230 0.000
R23 Other skin changes
0.768 0.232 0.000
S20-S29 Injuries to the thorax
0.767 0.233 0.000
M21.0 Valgus deformity, not elsewhere classified
0.767 0.233 0.000
M10 Gout
0.766 0.234 0.000
E11.2 With renal complications
0.764 0.236 0.000
Y00-Y09 Assault
0.764 0.236 0.000
G96 Other disorders of central nervous system
0.763 0.237 0.000
H43-H45 Disorders of vitreous body and globe
0.762 0.238 0.000
G70-G73 Diseases of myoneural junction and muscle
0.762 0.238 0.000
G30-G32 Other degenerative diseases of the nervous system
0.762 0.238 0.000
E10.4 With neurological complications
0.761 0.238 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.761 0.239 0.000
M54.9 Dorsalgia, unspecified
0.761 0.239 0.000
E11.5 With peripheral circulatory complications
0.760 0.240 0.000
R32 Unspecified urinary incontinence
0.760 0.240 0.000
N35.9 Urethral stricture, unspecified
0.759 0.241 0.000
M34 Systemic sclerosis
0.759 0.241 0.000
N50.0 Atrophy of testis
0.758 0.241 0.000
S70-S79 Injuries to the hip and thigh
0.757 0.243 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.757 0.243 0.000
M25.7 Osteophyte
0.756 0.244 0.000
M23.8 Other internal derangements of knee
0.756 0.244 0.000
Z50.1 Other physical therapy
0.756 0.244 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.756 0.244 0.000
E14 Unspecified diabetes mellitus
0.754 0.246 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.754 0.246 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.754 0.246 0.000
N43 Hydrocele and spermatocele
0.752 0.248 0.000
M46 Other inflammatory spondylopathies
0.750 0.250 0.000
V40-V49 Car occupant injured in transport accident
0.749 0.250 0.000
Z50.8 Care involving use of rehabilitation procedures
0.748 0.252 0.000
Z52 Donors of organs and tissues
0.748 0.252 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.747 0.253 0.000
S00 Superficial injury of head
0.745 0.255 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.745 0.255 0.000
M31 Other necrotising vasculopathies
0.744 0.255 0.000
M47.2 Other spondylosis with radiculopathy
0.744 0.256 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.743 0.256 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.743 0.257 0.000
R22.2 Localised swelling, mass and lump, trunk
0.742 0.258 0.000
M91-M94 Chondropathies
0.742 0.258 0.000
H27.1 Dislocation of lens
0.742 0.258 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.742 0.258 0.000
J40 Bronchitis, not specified as acute or chronic
0.741 0.259 0.000
E11.6 With other specified complications
0.739 0.261 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.739 0.261 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.738 0.262 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.737 0.262 0.000
F80-F89 Disorders of psychological development
0.736 0.264 0.000
H40 Glaucoma
0.736 0.264 0.000
Z48.8 Other specified surgical follow-up care
0.736 0.264 0.000
G91 Hydrocephalus
0.735 0.265 0.000
H90-H95 Other disorders of ear
0.735 0.265 0.000
R57 Shock, not elsewhere classified
0.735 0.265 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.734 0.266 0.000
G95.8 Other specified diseases of spinal cord
0.733 0.266 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.732 0.268 0.000
Z51.3 Blood transfusion without reported diagnosis
0.732 0.268 0.000
J42 Unspecified chronic bronchitis
0.730 0.269 0.000
Z73 Problems related to life-management difficulty
0.730 0.270 0.000
H53 Visual disturbances
0.730 0.270 0.000
Z57 Occupational exposure to risk-factors
0.728 0.272 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.727 0.272 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.727 0.273 0.000
M07 Psoriatic and enteropathic arthropathies
0.727 0.273 0.000
J98.9 Respiratory disorder, unspecified
0.727 0.273 0.000
M51.2 Other specified intervertebral disk displacement
0.726 0.273 0.000
G93 Other disorders of brain
0.726 0.274 0.000
Y86 Sequelae of other accidents
0.725 0.275 0.000
S80-S89 Injuries to the knee and lower leg
0.725 0.275 0.000
X60-X84 Intentional self-harm
0.725 0.275 0.000
M35 Other systemic involvement of connective tissue
0.724 0.275 0.000
G54 Nerve root and plexus disorders
0.724 0.276 0.000
M54.3 Sciatica
0.724 0.276 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.724 0.276 0.000
S10-S19 Injuries to the neck
0.723 0.277 0.000
R54 Senility
0.722 0.278 0.000
N18.0 End-stage renal disease
0.722 0.278 0.000
J98.8 Other specified respiratory disorders
0.722 0.278 0.000
Z36.8 Other antenatal screening
0.721 0.279 0.000
M11 Other crystal arthropathies
0.721 0.279 0.000
M19.09 Primary arthrosis of other joints (Site unspecified)
0.721 0.279 0.000
S90-S99 Injuries to the ankle and foot
0.720 0.279 0.000
H80-H83 Diseases of inner ear
0.720 0.280 0.000
J95.8 Other postprocedural respiratory disorders
0.719 0.281 0.000
H52.1 Myopia
0.719 0.281 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.719 0.281 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.718 0.282 0.000
M23.4 Loose body in knee
0.718 0.282 0.000
M17.0 Primary gonarthrosis, bilateral
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.715 0.285 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.715 0.285 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.714 0.286 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.714 0.286 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.714 0.286 0.000
N46 Male infertility
0.714 0.286 0.000
N44 Torsion of testis
0.714 0.286 0.000
M23.9 Internal derangement of knee, unspecified
0.713 0.287 0.000
M23.1 Discoid meniscus (congenital)
0.713 0.287 0.000
M23.0 Cystic meniscus
0.713 0.287 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.713 0.287 0.000
M40-M43 Deforming dorsopathies
0.713 0.287 0.000
N18.8 Other chronic renal failure
0.712 0.288 0.000
N18.1 Chronic kidney disease, stage 1
0.712 0.288 0.000
E40-E46 Malnutrition
0.711 0.289 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.711 0.289 0.000
F31 Bipolar affective disorder
0.711 0.289 0.000
R47-R49 Symptoms and signs involving speech and voice
0.710 0.290 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.710 0.290 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.710 0.290 0.000
M15 Polyarthrosis
0.709 0.291 0.000
H36 Retinal disorders in diseases classified elsewhere
0.709 0.291 0.000
N25-N29 Other disorders of kidney and ureter
0.709 0.291 0.000
E12 Malnutrition-related diabetes mellitus
0.709 0.291 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.709 0.291 0.000
Y35-Y36 Legal intervention and operations of war
0.709 0.291 0.000
Y10-Y34 Event of undetermined intent
0.709 0.291 0.000
X85-X99 Assault
0.709 0.291 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.709 0.291 0.000
X50-X57 Overexertion, travel and privation
0.709 0.291 0.000
X30-X39 Exposure to forces of nature
0.709 0.291 0.000
X20-X29 Contact with venomous animals and plants
0.709 0.291 0.000
X10-X19 Contact with heat and hot substances
0.709 0.291 0.000
X00-X09 Exposure to smoke, fire and flames
0.709 0.291 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.709 0.291 0.000
W75-W84 Other accidental threats to breathing
0.709 0.291 0.000
W65-W74 Accidental drowning and submersion
0.709 0.291 0.000
W50-W64 Exposure to animate mechanical forces
0.709 0.291 0.000
V98-V99 Other and unspecified transport accidents
0.709 0.291 0.000
V95-V97 Air and space transport accidents
0.709 0.291 0.000
V90-V94 Water transport accidents
0.709 0.291 0.000
V70-V79 Bus occupant injured in transport accident
0.709 0.291 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.709 0.291 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.709 0.291 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.709 0.291 0.000
V01-V09 Pedestrian injured in transport accident
0.709 0.291 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.709 0.291 0.000
N02 Recurrent and persistent haematuria
0.708 0.292 0.000
Z44 Fitting and adjustment of external prosthetic device
0.708 0.292 0.000
G47 Sleep disorders
0.708 0.292 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.707 0.293 0.000
R62 Lack of expected normal physiological development
0.707 0.293 0.000
R64 Cachexia
0.707 0.293 0.000
R58 Haemorrhage, not elsewhere classified
0.707 0.293 0.000
N45 Orchitis and epididymitis
0.707 0.293 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.707 0.293 0.000
H25.2 Senile cataract, morgagnian type
0.707 0.293 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.707 0.293 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.706 0.294 0.000
M51.9 Intervertebral disk disorder, unspecified
0.706 0.294 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.706 0.294 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.705 0.295 0.000
R63.5 Abnormal weight gain
0.705 0.295 0.000
R63.3 Feeding difficulties and mismanagement
0.705 0.295 0.000
R63.2 Polyphagia
0.705 0.295 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.705 0.295 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.704 0.296 0.000
M14 Arthropathies in other diseases classified elsewhere
0.704 0.296 0.000
M12 Other specific arthropathies
0.704 0.296 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.704 0.296 0.000
M08 Juvenile arthritis
0.704 0.296 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.704 0.296 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.703 0.296 0.000
N48.9 Disorder of penis, unspecified
0.703 0.297 0.000
N48.5 Ulcer of penis
0.703 0.297 0.000
N48.3 Priapism
0.703 0.297 0.000
R61 Hyperhidrosis
0.702 0.298 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.702 0.298 0.000
M49 Spondylopathies in diseases classified elsewhere
0.701 0.299 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.701 0.299 0.000
M19.8 Other specified arthrosis
0.701 0.299 0.000
M19.2 Other secondary arthrosis
0.701 0.299 0.000
M19.1 Posttraumatic arthrosis of other joints
0.701 0.299 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.700 0.300 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.699 0.301 0.000
V20-V29 Motorcycle rider injured in transport accident
0.699 0.301 0.000
M53 Other dorsopathies, not elsewhere classified
0.699 0.301 0.000
J15.2 Pneumonia due to staphylococcus
0.699 0.301 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.698 0.302 0.000
Q50-Q56 Congenital malformations of genital organs
0.698 0.302 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.698 0.302 0.000
J17 Pneumonia in diseases classified elsewhere
0.698 0.302 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.698 0.302 0.000
J12 Viral pneumonia, not elsewhere classified
0.698 0.302 0.000
J11 Influenza, virus not identified
0.698 0.302 0.000
J10 Influenza due to identified influenza virus
0.698 0.302 0.000
J14 Pneumonia due to Haemophilus influenzae
0.698 0.302 0.000
J09 Influenza due to certain identified influenza virus
0.698 0.302 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.698 0.302 0.000
F33 Recurrent depressive disorder
0.698 0.302 0.000
R22.0 Localised swelling, mass and lump, head
0.697 0.303 0.000
R59.9 Enlarged lymph nodes, unspecified
0.697 0.303 0.000
H25.9 Senile cataract, unspecified
0.696 0.304 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.696 0.304 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.696 0.304 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.696 0.304 0.000
J96 Respiratory failure, not elsewhere classified
0.696 0.304 0.000
G61 Inflammatory polyneuropathy
0.695 0.305 0.000
Q80-Q89 Other congenital malformations
0.695 0.305 0.000
H40.9 Glaucoma, unspecified
0.695 0.305 0.000
G63.2 Diabetic polyneuropathy
0.694 0.305 0.000
E13 Other specified diabetes mellitus
0.693 0.306 0.000
Z51.2 Other chemotherapy
0.693 0.307 0.000
G95.1 Vascular myelopathies
0.693 0.307 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.692 0.308 0.000
E10.8 With unspecified complications
0.691 0.309 0.000
E10.7 With multiple complications
0.691 0.309 0.000
E10.6 With other specified complications
0.691 0.309 0.000
E10.5 With peripheral circulatory complications
0.691 0.309 0.000
E10.0 With coma
0.691 0.309 0.000
M82 Osteoporosis in diseases classified elsewhere
0.691 0.309 0.000
N34 Urethritis and urethral syndrome
0.690 0.310 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.690 0.310 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.690 0.310 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.689 0.311 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.689 0.311 0.000
G92 Toxic encephalopathy
0.689 0.311 0.000
M50 Cervical disk disorders
0.688 0.312 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.687 0.313 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.686 0.314 0.000
G51 Facial nerve disorders
0.686 0.314 0.000
E11.8 With unspecified complications
0.686 0.314 0.000
E11.7 With multiple complications
0.686 0.314 0.000
E11.0 With coma
0.686 0.314 0.000
M06.8 Other specified rheumatoid arthritis
0.685 0.314 0.000
M06.4 Inflammatory polyarthropathy
0.685 0.314 0.000
M06.3 Rheumatoid nodule
0.685 0.314 0.000
M06.2 Rheumatoid bursitis
0.685 0.314 0.000
M06.1 Adult-onset Still's disease
0.685 0.314 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.685 0.315 0.000
Chapter I Certain infectious and parasitic diseases
0.685 0.315 0.000
M25.3 Other instability of joint
0.685 0.315 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.685 0.315 0.000
J18.8 Other pneumonia, organism unspecified
0.684 0.316 0.000
J18.2 Hypostatic pneumonia, unspecified
0.684 0.316 0.000
T90 Sequelae of injuries of head
0.683 0.317 0.000
T79-T79 Certain early complications of trauma
0.683 0.317 0.000
R23.3 Spontaneous ecchymoses
0.683 0.317 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.683 0.317 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.682 0.318 0.000
M19.98 Arthrosis, unspecified (Other)
0.682 0.318 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.681 0.319 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.680 0.320 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.680 0.320 0.000
M48.02 Spinal stenosis (Cervical region)
0.679 0.320 0.000
M84 Disorders of continuity of bone
0.679 0.321 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.678 0.321 0.000
Z51.9 Medical care, unspecified
0.678 0.322 0.000
Z51.6 Desensitisation to allergens
0.678 0.322 0.000
Z49 Care involving dialysis
0.677 0.323 0.000
N50.9 Disorder of male genital organs, unspecified
0.677 0.323 0.000
Z50.6 Orthoptic training
0.676 0.324 0.000
Z50.3 Drug rehabilitation
0.676 0.324 0.000
Z50.2 Alcohol rehabilitation
0.676 0.324 0.000
N41 Inflammatory diseases of prostate
0.676 0.324 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.675 0.325 0.000
N05 Unspecified nephritic syndrome
0.675 0.325 0.000
Z74 Problems related to care-provider dependency
0.674 0.326 0.000
M54.1 Radiculopathy
0.674 0.326 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.674 0.326 0.000
S00.0 Superficial injury of scalp
0.673 0.327 0.000
M24.1 Other articular cartilage disorders
0.673 0.327 0.000
M22.4 Chondromalacia patellae
0.671 0.329 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.671 0.329 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.671 0.329 0.000
M54.5 Low back pain
0.671 0.329 0.000
J90-J94 Other diseases of pleura
0.670 0.330 0.000
M25.8 Other specified joint disorders
0.669 0.331 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.669 0.331 0.000
J98.6 Disorders of diaphragm
0.669 0.331 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.669 0.331 0.000
J98.3 Compensatory emphysema
0.669 0.331 0.000
J98.2 Interstitial emphysema
0.669 0.331 0.000
H57 Other disorders of eye and adnexa
0.668 0.332 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.668 0.332 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.668 0.332 0.000
N04 Nephrotic syndrome
0.667 0.333 0.000
R79 Other abnormal findings of blood chemistry
0.667 0.333 0.000
J43 Emphysema
0.667 0.333 0.000
N76 Other inflammation of vagina and vulva
0.667 0.333 0.000
G60 Hereditary and idiopathic neuropathy
0.666 0.334 0.000
M17.5 Other secondary gonarthrosis
0.666 0.334 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.666 0.334 0.000
M17.3 Other posttraumatic gonarthrosis
0.666 0.334 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.666 0.334 0.000
J98.1 Pulmonary collapse
0.665 0.335 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.665 0.335 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.665 0.335 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.665 0.335 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.665 0.335 0.000
N48.4 Impotence of organic origin
0.664 0.336 0.000
M51.3 Other specified intervertebral disk degeneration
0.663 0.336 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.663 0.336 0.000
M51.4 Schmorl's nodes
0.663 0.336 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.663 0.337 0.000
Z36.9 Antenatal screening, unspecified
0.663 0.337 0.000
N36 Other disorders of urethra
0.663 0.337 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.663 0.337 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.662 0.338 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.662 0.338 0.000
N99-N99 Other disorders of the genitourinary system
0.661 0.338 0.000
N42.9 Disorder of prostate, unspecified
0.661 0.339 0.000
G58 Other mononeuropathies
0.661 0.339 0.000
M17.1 Other primary gonarthrosis
0.661 0.339 0.000
M47.1 Other spondylosis with myelopathy
0.661 0.339 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.661 0.339 0.000
M21.9 Acquired deformity of limb, unspecified
0.660 0.340 0.000
M21.8 Other specified acquired deformities of limbs
0.660 0.340 0.000
M21.7 Unequal limb length (acquired)
0.660 0.340 0.000
M21.6 Other acquired deformities of ankle and foot
0.660 0.340 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.660 0.340 0.000
M21.4 Flat foot [pes planus] (acquired)
0.660 0.340 0.000
M21.2 Flexion deformity
0.660 0.340 0.000
M21.1 Varus deformity, not elsewhere classified
0.660 0.340 0.000
N30.1 Interstitial cystitis (chronic)
0.660 0.340 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.657 0.343 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.657 0.343 0.000
W20-W49 Exposure to inanimate mechanical forces
0.657 0.343 0.000
R56 Convulsions, not elsewhere classified
0.657 0.343 0.000
H10-H13 Disorders of conjunctiva
0.656 0.344 0.000
N49.2 Inflammatory disorders of scrotum
0.654 0.346 0.000
Z43.9 Attention to unspecified artificial opening
0.654 0.346 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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