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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75593565
log Bayes Factor = 13.6234
Chromosome 12   position 32,115,266  (GRCh37) Explore rs75593565 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.999 0.001 0.000
S00-S09 Injuries to the head
0.998 0.002 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
Chapter XXI Factors influencing health status and contact with health services
0.996 0.004 0.000
F30-F39 Mood [affective] disorders
0.996 0.004 0.000
Chapter II Neoplasms
0.994 0.006 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.993 0.007 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.992 0.008 0.000
C15-C26 Malignant neoplasms of digestive organs
0.989 0.011 0.000
F10.2 Dependence syndrome
0.988 0.012 0.000
S00 Superficial injury of head
0.987 0.013 0.000
F31 Bipolar affective disorder
0.984 0.016 0.000
Chapter IX Diseases of the circulatory system
0.984 0.016 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.982 0.018 0.000
I60-I69 Cerebrovascular diseases
0.981 0.019 0.000
C25 Malignant neoplasm of pancreas
0.971 0.029 0.000
F10.0 Acute intoxication
0.968 0.032 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.966 0.034 0.000
Z50 Care involving use of rehabilitation procedures
0.960 0.040 0.000
S00.8 Superficial injury of other parts of head
0.957 0.043 0.000
Y43 Primarily systemic agents
0.956 0.044 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.951 0.049 0.000
S80-S89 Injuries to the knee and lower leg
0.944 0.056 0.000
Chapter VI Diseases of the nervous system
0.942 0.058 0.000
I61 Intracerebral haemorrhage
0.937 0.063 0.000
Z36 Antenatal screening
0.933 0.067 0.000
I67 Other cerebrovascular diseases
0.929 0.071 0.000
G90-G99 Other disorders of the nervous system
0.929 0.071 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.927 0.073 0.000
O36 Maternal care for other known or suspected foetal problems
0.927 0.073 0.000
C25.0 Head of pancreas
0.926 0.074 0.000
Y43.3 Other antineoplastic drugs
0.920 0.080 0.000
Chapter I Certain infectious and parasitic diseases
0.919 0.081 0.000
O60-O75 Complications of labour and delivery
0.919 0.081 0.000
C18 Malignant neoplasm of colon
0.912 0.088 0.000
Z35 Supervision of high-risk pregnancy
0.911 0.089 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.905 0.095 0.000
Chapter XI Diseases of the digestive system
0.904 0.096 0.000
S81 Open wound of lower leg
0.900 0.100 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.896 0.104 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.896 0.104 0.000
C25.9 Pancreas, unspecified
0.896 0.104 0.000
I67.8 Other specified cerebrovascular diseases
0.894 0.106 0.000
S06 Intracranial injury
0.894 0.106 0.000
F32 Depressive episode
0.887 0.113 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.885 0.115 0.000
S02 Fracture of skull and facial bones
0.882 0.118 0.000
Chapter VIII Diseases of the ear and mastoid process
0.882 0.118 0.000
Y52 Agents primarily affecting the cardiovascular system
0.880 0.120 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.879 0.121 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.878 0.122 0.000
C18.7 Sigmoid colon
0.877 0.123 0.000
Z50.1 Other physical therapy
0.873 0.127 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.873 0.127 0.000
Z30 Contraceptive management
0.872 0.128 0.000
Z45 Adjustment and management of implanted device
0.871 0.129 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.868 0.132 0.000
D46 Myelodysplastic syndromes
0.860 0.140 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.859 0.141 0.000
F31.9 Bipolar affective disorder, unspecified
0.858 0.142 0.000
I62 Other nontraumatic intracranial haemorrhage
0.858 0.142 0.000
S70-S79 Injuries to the hip and thigh
0.857 0.143 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.852 0.148 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.852 0.148 0.000
O00-O08 Pregnancy with abortive outcome
0.852 0.148 0.000
K83 Other diseases of biliary tract
0.851 0.149 0.000
Z50.0 Cardiac rehabilitation
0.849 0.151 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.845 0.155 0.000
Z50.2 Alcohol rehabilitation
0.841 0.159 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.840 0.160 0.000
S81.0 Open wound of knee
0.838 0.162 0.000
O80-O84 Delivery
0.837 0.163 0.000
K86 Other diseases of pancreas
0.836 0.164 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.835 0.165 0.000
Chapter XXII Codes for special purposes
0.830 0.170 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.829 0.171 0.000
F10.4 Withdrawal state with delirium
0.827 0.173 0.000
O42 Premature rupture of membranes
0.826 0.174 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.826 0.174 0.000
A30-A49 Other bacterial diseases
0.825 0.175 0.000
S00.7 Multiple superficial injuries of head
0.824 0.176 0.000
S50-S59 Injuries to the elbow and forearm
0.824 0.176 0.000
I63 Cerebral infarction
0.822 0.178 0.000
Y44 Agents primarily affecting blood constituents
0.821 0.179 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.820 0.180 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.820 0.180 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.818 0.182 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.818 0.182 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.818 0.182 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.817 0.183 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.816 0.184 0.000
S09 Other and unspecified injuries of head
0.816 0.184 0.000
B35-B49 Mycoses
0.813 0.187 0.000
K90-K93 Other diseases of the digestive system
0.813 0.187 0.000
O36.8 Maternal care for other specified foetal problems
0.812 0.188 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.811 0.189 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.809 0.191 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.807 0.193 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.807 0.193 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.806 0.194 0.000
C23 Malignant neoplasm of gallbladder
0.806 0.194 0.000
H65-H75 Diseases of middle ear and mastoid
0.806 0.194 0.000
C21 Malignant neoplasm of anus and anal canal
0.805 0.195 0.000
Z30.2 Sterilisation
0.803 0.197 0.000
Y40 Systemic antibiotics
0.803 0.197 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.801 0.199 0.000
K83.1 Obstruction of bile duct
0.800 0.200 0.000
Z50.8 Care involving use of rehabilitation procedures
0.797 0.203 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.795 0.205 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.795 0.205 0.000
K81 Cholecystitis
0.794 0.206 0.000
O36.9 Maternal care for foetal problem, unspecified
0.794 0.206 0.000
Z36.9 Antenatal screening, unspecified
0.792 0.208 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.792 0.208 0.000
Z35.1 Supervision of pregnancy with history of abortive outcome
0.791 0.209 0.000
S00.1 Contusion of eyelid and periocular area
0.791 0.209 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.789 0.210 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.789 0.211 0.000
Z51 Other medical care
0.788 0.212 0.000
Z45.2 Adjustment and management of vascular access device
0.787 0.213 0.000
G93 Other disorders of brain
0.786 0.214 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.786 0.214 0.000
W00-W19 Falls
0.783 0.217 0.000
Z36.2 Other antenatal screening based on amniocentesis
0.783 0.217 0.000
S06.2 Diffuse brain injury
0.780 0.220 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.776 0.224 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.775 0.225 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.775 0.225 0.000
I30-I52 Other forms of heart disease
0.775 0.225 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.774 0.226 0.000
Z43 Attention to artificial openings
0.774 0.226 0.000
Z35.8 Supervision of other high-risk pregnancies
0.774 0.226 0.000
V80-V89 Other land transport accidents
0.773 0.227 0.000
S60-S69 Injuries to the wrist and hand
0.772 0.228 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.769 0.231 0.000
C17 Malignant neoplasm of small intestine
0.769 0.231 0.000
C16 Malignant neoplasm of stomach
0.769 0.231 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.769 0.231 0.000
O30 Multiple gestation
0.768 0.232 0.000
Z46 Fitting and adjustment of other devices
0.767 0.233 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.765 0.235 0.000
F30 Manic episode
0.764 0.236 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.763 0.237 0.000
S40-S49 Injuries to the shoulder and upper arm
0.763 0.237 0.000
F32.1 Moderate depressive episode
0.762 0.238 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.761 0.238 0.000
F33 Recurrent depressive disorder
0.761 0.239 0.000
Y43.4 Immunosuppressive agents
0.761 0.239 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.761 0.239 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.760 0.240 0.000
O85-O92 Complications predominantly related to the puerperium
0.760 0.240 0.000
H65 Nonsuppurative otitis media
0.759 0.240 0.000
S81.9 Open wound of lower leg, part unspecified
0.759 0.241 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.759 0.241 0.000
Z37 Outcome of delivery
0.759 0.241 0.000
S00.0 Superficial injury of scalp
0.758 0.242 0.000
O72 Postpartum haemorrhage
0.758 0.242 0.000
I60 Subarachnoid haemorrhage
0.756 0.244 0.000
A49 Bacterial infection of unspecified site
0.756 0.244 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.751 0.249 0.000
C09 Malignant neoplasm of tonsil
0.748 0.252 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.747 0.253 0.000
O44 Placenta praevia
0.746 0.253 0.000
Z51.5 Palliative care
0.745 0.255 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.744 0.256 0.000
S10-S19 Injuries to the neck
0.743 0.257 0.000
K81.9 Cholecystitis, unspecified
0.741 0.259 0.000
O47 False labour
0.740 0.260 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.740 0.260 0.000
H80-H83 Diseases of inner ear
0.739 0.260 0.000
K86.2 Cyst of pancreas
0.739 0.261 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.738 0.262 0.000
G95 Other diseases of spinal cord
0.734 0.266 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.734 0.266 0.000
D45 Polycythaemia vera
0.733 0.267 0.000
I05-I09 Chronic rheumatic heart diseases
0.732 0.267 0.000
T93 Sequelae of injuries of lower limb
0.732 0.268 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.732 0.268 0.000
C18.0 Caecum
0.732 0.268 0.000
S06.8 Other intracranial injuries
0.731 0.269 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.730 0.270 0.000
O04 Medical abortion
0.730 0.270 0.000
Z50.5 Speech therapy
0.729 0.271 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.728 0.272 0.000
K90 Intestinal malabsorption
0.727 0.273 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.727 0.273 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.727 0.273 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.727 0.273 0.000
K85 Acute pancreatitis
0.726 0.274 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.726 0.274 0.000
I45 Other conduction disorders
0.726 0.274 0.000
I26 Pulmonary embolism
0.726 0.274 0.000
S72 Fracture of femur
0.725 0.275 0.000
V10-V19 Pedal cyclist injured in transport accident
0.724 0.275 0.000
F32.9 Depressive episode, unspecified
0.724 0.276 0.000
S90-S99 Injuries to the ankle and foot
0.723 0.277 0.000
O41 Other disorders of amniotic fluid and membranes
0.723 0.277 0.000
D43.2 Brain, unspecified
0.723 0.277 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.722 0.278 0.000
B95-B98 Bacterial, viral and other infectious agents
0.721 0.279 0.000
C51-C58 Malignant neoplasms of female genital organs
0.721 0.279 0.000
K86.8 Other specified diseases of pancreas
0.720 0.280 0.000
B37 Candidiasis
0.720 0.280 0.000
S00.3 Superficial injury of nose
0.720 0.280 0.000
X60-X84 Intentional self-harm
0.719 0.280 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.719 0.281 0.000
K83.0 Cholangitis
0.717 0.283 0.000
Z51.3 Blood transfusion without reported diagnosis
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
F60-F69 Disorders of adult personality and behaviour
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
O02 Other abnormal products of conception
0.716 0.283 0.000
Z54 Convalescence
0.716 0.284 0.000
C01 Malignant neoplasm of base of tongue
0.716 0.284 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.716 0.284 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.716 0.284 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.716 0.284 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.716 0.284 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.716 0.284 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.716 0.284 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.716 0.284 0.000
F11 Mental and behavioural disorders due to use of opioids
0.716 0.284 0.000
O40 Polyhydramnios
0.716 0.284 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.715 0.284 0.000
S08 Traumatic amputation of part of head
0.715 0.285 0.000
S07 Crushing injury of head
0.715 0.285 0.000
S05 Injury of eye and orbit
0.715 0.285 0.000
S04 Injury of cranial nerves
0.715 0.285 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.715 0.285 0.000
F10.9 Unspecified mental and behavioural disorder
0.715 0.285 0.000
F10.8 Other mental and behavioural disorders
0.715 0.285 0.000
F10.7 Residual and late-onset psychotic disorder
0.715 0.285 0.000
F10.6 Amnesic syndrome
0.715 0.285 0.000
F10.5 Psychotic disorder
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
G30-G32 Other degenerative diseases of the nervous system
0.714 0.286 0.000
F38 Other mood [affective] disorders
0.714 0.286 0.000
F34 Persistent mood [affective] disorders
0.714 0.286 0.000
F39 Unspecified mood [affective] disorder
0.714 0.286 0.000
O16 Unspecified maternal hypertension
0.713 0.287 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.713 0.287 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.713 0.287 0.000
T90 Sequelae of injuries of head
0.712 0.288 0.000
Y59 Other and unspecified vaccines and biological substances
0.712 0.288 0.000
Y58 Bacterial vaccines
0.712 0.288 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.712 0.288 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.712 0.288 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.712 0.288 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.712 0.288 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.712 0.288 0.000
Y48 Anaesthetics and therapeutic gases
0.712 0.288 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.712 0.288 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.712 0.288 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.712 0.288 0.000
O45 Premature separation of placenta [abruptio placentae]
0.711 0.289 0.000
O43 Placental disorders
0.711 0.289 0.000
O33 Maternal care for known or suspected disproportion
0.711 0.289 0.000
O31 Complications specific to multiple gestation
0.711 0.289 0.000
O82 Single delivery by Caesarean section
0.711 0.289 0.000
C79 Secondary malignant neoplasm of other sites
0.710 0.290 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.710 0.290 0.000
G90 Disorders of autonomic nervous system
0.709 0.290 0.000
Z32 Pregnancy examination and test
0.709 0.291 0.000
Y57 Other and unspecified drugs and medicaments
0.709 0.291 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.709 0.291 0.000
Z35.5 Supervision of elderly primigravida
0.709 0.291 0.000
K82 Other diseases of gallbladder
0.708 0.292 0.000
G70-G73 Diseases of myoneural junction and muscle
0.708 0.292 0.000
S00.5 Superficial injury of lip and oral cavity
0.708 0.292 0.000
S00.4 Superficial injury of ear
0.708 0.292 0.000
S02.6 Fracture of mandible
0.708 0.292 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.707 0.293 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.706 0.293 0.000
C45 Mesothelioma
0.706 0.294 0.000
S20-S29 Injuries to the thorax
0.706 0.294 0.000
F31.8 Other bipolar affective disorders
0.706 0.294 0.000
F31.7 Bipolar affective disorder, currently in remission
0.706 0.294 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.706 0.294 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.706 0.294 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.706 0.294 0.000
F99-F99 Unspecified mental disorder
0.706 0.294 0.000
O48 Prolonged pregnancy
0.706 0.294 0.000
I67.1 Cerebral aneurysm, nonruptured
0.705 0.294 0.000
O34.1 Maternal care for tumour of corpus uteri
0.705 0.295 0.000
I00-I02 Acute rheumatic fever
0.705 0.295 0.000
F42 Obsessive-compulsive disorder
0.705 0.295 0.000
Z38 Liveborn infants according to place of birth
0.704 0.296 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.704 0.296 0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history
0.704 0.296 0.000
I67.9 Cerebrovascular disease, unspecified
0.704 0.296 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.703 0.296 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.703 0.296 0.000
Q50-Q56 Congenital malformations of genital organs
0.701 0.299 0.000
S00.9 Superficial injury of head, part unspecified
0.699 0.300 0.000
S52 Fracture of forearm
0.698 0.302 0.000
S06.20 Diffuse brain injury (without open intracranial wound)
0.698 0.302 0.000
Y44.2 Anticoagulants
0.698 0.302 0.000
I45.6 Preexcitation syndrome
0.697 0.303 0.000
S32 Fracture of lumbar spine and pelvis
0.697 0.303 0.000
S82 Fracture of lower leg, including ankle
0.696 0.304 0.000
F10.3 Withdrawal state
0.696 0.304 0.000
C25.8 Overlapping lesion of pancreas
0.696 0.304 0.000
C25.7 Other parts of pancreas
0.696 0.304 0.000
C25.4 Endocrine pancreas
0.696 0.304 0.000
C25.3 Pancreatic duct
0.696 0.304 0.000
C25.2 Tail of pancreas
0.696 0.304 0.000
C25.1 Body of pancreas
0.696 0.304 0.000
I74 Arterial embolism and thrombosis
0.696 0.304 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.696 0.304 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.696 0.304 0.000
F32.0 Mild depressive episode
0.695 0.304 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.695 0.305 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.695 0.305 0.000
Z31 Procreative management
0.694 0.306 0.000
F80-F89 Disorders of psychological development
0.693 0.306 0.000
S02.0 Fracture of vault of skull
0.693 0.307 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.693 0.307 0.000
S02.1 Fracture of base of skull
0.693 0.307 0.000
Y52.1 Calcium-channel blockers
0.693 0.307 0.000
I34 Nonrheumatic mitral valve disorders
0.693 0.307 0.000
Z44 Fitting and adjustment of external prosthetic device
0.692 0.307 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.692 0.308 0.000
A49.0 Staphylococcal infection, unspecified
0.691 0.309 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.690 0.310 0.000
A46 Erysipelas
0.689 0.311 0.000
Z50.6 Orthoptic training
0.688 0.312 0.000
Z50.3 Drug rehabilitation
0.688 0.312 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.688 0.312 0.000
Z45.8 Adjustment and management of other implanted devices
0.688 0.312 0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device
0.686 0.314 0.000
V20-V29 Motorcycle rider injured in transport accident
0.686 0.314 0.000
F43 Reaction to severe stress, and adjustment disorders
0.686 0.314 0.000
Z37.2 Twins, both liveborn
0.686 0.314 0.000
S09.9 Unspecified injury of head
0.686 0.314 0.000
Y43.9 Primarily systemic agent, unspecified
0.685 0.315 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.685 0.315 0.000
Y43.6 Enzymes, not elsewhere classified
0.685 0.315 0.000
Y43.5 Acidifying and alkalising agents
0.685 0.315 0.000
Y43.2 Antineoplastic natural products
0.685 0.315 0.000
Y43.1 Antineoplastic antimetabolites
0.685 0.315 0.000
Y43.0 Antiallergic and antiemetic drugs
0.685 0.315 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.685 0.315 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.684 0.316 0.000
C02.1 Border of tongue
0.682 0.318 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.682 0.318 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.682 0.318 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.682 0.318 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.682 0.318 0.000
H73 Other disorders of tympanic membrane
0.682 0.318 0.000
T79-T79 Certain early complications of trauma
0.680 0.320 0.000
S02.8 Fractures of other skull and facial bones
0.680 0.320 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.680 0.320 0.000
Z75 Problems related to medical facilities and other health care
0.680 0.320 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.680 0.320 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.679 0.321 0.000
S02.3 Fracture of orbital floor
0.677 0.323 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.677 0.323 0.000
S88 Traumatic amputation of lower leg
0.677 0.323 0.000
S87 Crushing injury of lower leg
0.677 0.323 0.000
S86 Injury of muscle and tendon at lower leg level
0.677 0.323 0.000
S85 Injury of blood vessels at lower leg level
0.677 0.323 0.000
S84 Injury of nerves at lower leg level
0.677 0.323 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.677 0.323 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.677 0.323 0.000
O61 Failed induction of labour
0.676 0.324 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.676 0.324 0.000
O46.9 Antepartum haemorrhage, unspecified
0.675 0.325 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.674 0.325 0.000
O73 Retained placenta and membranes, without haemorrhage
0.674 0.325 0.000
I63.8 Other cerebral infarction
0.674 0.326 0.000
C21.0 Anus, unspecified
0.674 0.326 0.000
Y85 Sequelae of transport accidents
0.674 0.326 0.000
S62 Fracture at wrist and hand level
0.674 0.326 0.000
B15-B19 Viral hepatitis
0.673 0.327 0.000
I61.8 Other intracerebral haemorrhage
0.672 0.328 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.672 0.328 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.672 0.328 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.672 0.328 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.672 0.328 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.672 0.328 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.672 0.328 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.672 0.328 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.671 0.329 0.000
I31 Other diseases of pericardium
0.669 0.331 0.000
Z36.5 Antenatal screening for isoimmunisation
0.669 0.331 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.669 0.331 0.000
Z36.1 Antenatal screening for raised alphafetoprotein level
0.669 0.331 0.000
S81.8 Open wound of other parts of lower leg
0.669 0.331 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.669 0.331 0.000
S70 Superficial injury of hip and thigh
0.668 0.332 0.000
O62 Abnormalities of forces of labour
0.667 0.333 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.666 0.334 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.666 0.334 0.000
I67.5 Moyamoya disease
0.666 0.334 0.000
I67.4 Hypertensive encephalopathy
0.666 0.334 0.000
I67.3 Progressive vascular leukoencephalopathy
0.666 0.334 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.666 0.334 0.000
O42.9 Premature rupture of membranes, unspecified
0.666 0.334 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.666 0.334 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.666 0.334 0.000
G92 Toxic encephalopathy
0.666 0.334 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.666 0.334 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.666 0.334 0.000
C13 Malignant neoplasm of hypopharynx
0.665 0.335 0.000
C11 Malignant neoplasm of nasopharynx
0.665 0.335 0.000
C10 Malignant neoplasm of oropharynx
0.665 0.335 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.665 0.335 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.665 0.335 0.000
C05 Malignant neoplasm of palate
0.665 0.335 0.000
C04 Malignant neoplasm of floor of mouth
0.665 0.335 0.000
C03 Malignant neoplasm of gum
0.665 0.335 0.000
C00 Malignant neoplasm of lip
0.665 0.335 0.000
C12 Malignant neoplasm of pyriform sinus
0.665 0.335 0.000
C07 Malignant neoplasm of parotid gland
0.665 0.335 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.665 0.335 0.000
O36.6 Maternal care for excessive foetal growth
0.665 0.335 0.000
O36.4 Maternal care for intra-uterine death
0.665 0.335 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.665 0.335 0.000
O36.2 Maternal care for hydrops foetalis
0.665 0.335 0.000
O36.1 Maternal care for other isoimmunisation
0.665 0.335 0.000
S80 Superficial injury of lower leg
0.664 0.336 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.664 0.336 0.000
D00-D09 In situ neoplasms
0.663 0.337 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.663 0.337 0.000
S72.1 Pertrochanteric fracture
0.663 0.337 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.663 0.337 0.000
Z29 Need for other prophylactic measures
0.660 0.340 0.000
F17.1 Harmful use
0.660 0.340 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.659 0.341 0.000
B99-B99 Other infectious diseases
0.659 0.341 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.659 0.341 0.000
B65-B83 Helminthiases
0.659 0.341 0.000
B50-B64 Protozoal diseases
0.659 0.341 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.659 0.341 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.659 0.341 0.000
A75-A79 Rickettsioses
0.659 0.341 0.000
A70-A74 Other diseases caused by chlamydiae
0.659 0.341 0.000
A65-A69 Other spirochaetal diseases
0.659 0.341 0.000
A20-A28 Certain zoonotic bacterial diseases
0.659 0.341 0.000
A15-A19 Tuberculosis
0.659 0.341 0.000
O74 Complications of anaesthesia during labour and delivery
0.659 0.341 0.000
O71 Other obstetric trauma
0.659 0.341 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.659 0.341 0.000
O60 Preterm delivery
0.659 0.341 0.000
F17.2 Dependence syndrome
0.659 0.341 0.000
C18.5 Splenic flexure
0.658 0.341 0.000
K81.1 Chronic cholecystitis
0.658 0.341 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.658 0.342 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.658 0.342 0.000
C15 Malignant neoplasm of oesophagus
0.658 0.342 0.000
K90.0 Coeliac disease
0.657 0.343 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.657 0.343 0.000
Y40.0 Penicillins
0.657 0.343 0.000
A80-A89 Viral infections of the central nervous system
0.657 0.343 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.657 0.343 0.000
Z33 Pregnant state, incidental
0.657 0.343 0.000
S89 Other and unspecified injuries of lower leg
0.656 0.344 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.656 0.344 0.000
C18.4 Transverse colon
0.655 0.345 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.655 0.345 0.000
O66 Other obstructed labour
0.655 0.345 0.000
G93.9 Disorder of brain, unspecified
0.655 0.345 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.654 0.345 0.000
C18.8 Overlapping lesion of colon
0.654 0.346 0.000
C18.6 Descending colon
0.654 0.346 0.000
C18.1 Appendix
0.654 0.346 0.000
Z35.9 Supervision of high-risk pregnancy, unspecified
0.653 0.347 0.000
Z35.7 Supervision of high-risk pregnancy due to social problems
0.653 0.347 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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