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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76365676
log Bayes Factor = 12.2448
Chromosome 4   position 3,387,221  (GRCh37) Explore rs76365676 on Ensembl!
Variant rs76365676 is part of Cluster X0232

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
I50 Heart failure
0.998 0.002 0.000
I51 Complications and ill-defined descriptions of heart disease
0.998 0.002 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.998 0.002 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.995 0.005 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.994 0.006 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.992 0.008 0.000
I51.8 Other ill-defined heart diseases
0.989 0.011 0.000
S00-S09 Injuries to the head
0.988 0.012 0.000
F30-F39 Mood [affective] disorders
0.987 0.013 0.000
F32 Depressive episode
0.982 0.018 0.000
F32.9 Depressive episode, unspecified
0.979 0.021 0.000
I50.9 Heart failure, unspecified
0.978 0.022 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.977 0.023 0.000
R13 Dysphagia
0.970 0.030 0.000
I73 Other peripheral vascular diseases
0.958 0.042 0.000
Chapter XX External causes of morbidity and mortality
0.952 0.048 0.000
M50-M54 Other dorsopathies
0.946 0.054 0.000
S00 Superficial injury of head
0.942 0.058 0.000
I73.9 Peripheral vascular disease, unspecified
0.937 0.063 0.000
R11 Nausea and vomiting
0.937 0.063 0.000
I50.0 Congestive heart failure
0.936 0.064 0.000
M54 Dorsalgia
0.935 0.065 0.000
E10-E14 Diabetes mellitus
0.933 0.067 0.000
R14 Flatulence and related conditions
0.929 0.071 0.000
M20-M25 Other joint disorders
0.927 0.073 0.000
Chapter VI Diseases of the nervous system
0.925 0.075 0.000
I51.9 Heart disease, unspecified
0.922 0.078 0.000
M05-M14 Inflammatory polyarthropathies
0.919 0.081 0.000
R50-R69 General symptoms and signs
0.919 0.081 0.000
I74 Arterial embolism and thrombosis
0.917 0.082 0.000
I50.1 Left ventricular failure
0.916 0.084 0.000
Chapter VII Diseases of the eye and adnexa
0.916 0.084 0.000
M25 Other joint disorders, not elsewhere classified
0.914 0.086 0.000
E10 Insulin-dependent diabetes mellitus
0.911 0.089 0.000
M54.2 Cervicalgia
0.895 0.105 0.000
E20-E35 Disorders of other endocrine glands
0.890 0.110 0.000
M25.7 Osteophyte
0.889 0.111 0.000
S70-S79 Injuries to the hip and thigh
0.889 0.111 0.000
M06 Other rheumatoid arthritis
0.882 0.118 0.000
I42 Cardiomyopathy
0.879 0.121 0.000
E70-E90 Metabolic disorders
0.877 0.123 0.000
S06 Intracranial injury
0.872 0.128 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.872 0.128 0.000
S09 Other and unspecified injuries of head
0.871 0.129 0.000
I72 Other aneurysm
0.868 0.132 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.864 0.136 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.864 0.136 0.000
G90-G99 Other disorders of the nervous system
0.863 0.137 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.863 0.137 0.000
M25.77 Osteophyte (Ankle and foot)
0.860 0.140 0.000
S80-S89 Injuries to the knee and lower leg
0.855 0.145 0.000
I51.6 Cardiovascular disease, unspecified
0.854 0.146 0.000
M54.22 Cervicalgia (Cervical region)
0.853 0.147 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.852 0.148 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.848 0.152 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.844 0.156 0.000
I35 Nonrheumatic aortic valve disorders
0.843 0.157 0.000
E10.3 With ophthalmic complications
0.838 0.162 0.000
H04 Disorders of lachrymal system
0.835 0.165 0.000
R52 Pain, not elsewhere classified
0.832 0.168 0.000
M06.9 Rheumatoid arthritis, unspecified
0.832 0.168 0.000
W00-W19 Falls
0.832 0.168 0.000
H55-H59 Other disorders of eye and adnexa
0.829 0.170 0.000
M21 Other acquired deformities of limbs
0.829 0.171 0.000
M80-M85 Disorders of bone density and structure
0.829 0.171 0.000
S00.0 Superficial injury of scalp
0.827 0.173 0.000
R61 Hyperhidrosis
0.820 0.180 0.000
S05 Injury of eye and orbit
0.818 0.182 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.817 0.183 0.000
M54.5 Low back pain
0.815 0.185 0.000
I70 Atherosclerosis
0.814 0.186 0.000
E40-E46 Malnutrition
0.814 0.186 0.000
R59 Enlarged lymph nodes
0.812 0.188 0.000
M54.9 Dorsalgia, unspecified
0.811 0.189 0.000
Chapter VIII Diseases of the ear and mastoid process
0.810 0.190 0.000
G93 Other disorders of brain
0.809 0.190 0.000
M45-M49 Spondylopathies
0.809 0.191 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.809 0.191 0.000
I46 Cardiac arrest
0.807 0.193 0.000
F80-F89 Disorders of psychological development
0.807 0.193 0.000
E10.9 Without complications
0.807 0.193 0.000
S40-S49 Injuries to the shoulder and upper arm
0.805 0.195 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.804 0.196 0.000
S72 Fracture of femur
0.803 0.197 0.000
M25.4 Effusion of joint
0.801 0.199 0.000
M65-M68 Disorders of synovium and tendon
0.800 0.200 0.000
I83 Varicose veins of lower extremities
0.798 0.202 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.797 0.203 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.797 0.203 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.791 0.209 0.000
R54 Senility
0.790 0.210 0.000
S09.9 Unspecified injury of head
0.787 0.213 0.000
I77 Other disorders of arteries and arterioles
0.784 0.216 0.000
M54.56 Low back pain (Lumbar region)
0.783 0.217 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.783 0.217 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.781 0.219 0.000
I42.9 Cardiomyopathy, unspecified
0.780 0.220 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.777 0.223 0.000
D50-D53 Nutritional anaemias
0.775 0.224 0.000
F60-F69 Disorders of adult personality and behaviour
0.775 0.225 0.000
I71 Aortic aneurysm and dissection
0.773 0.227 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.769 0.231 0.000
M25.74 Osteophyte (Hand)
0.769 0.231 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.769 0.231 0.000
M70-M79 Other soft tissue disorders
0.769 0.231 0.000
Chapter I Certain infectious and parasitic diseases
0.768 0.232 0.000
H30-H36 Disorders of choroid and retina
0.768 0.232 0.000
I35.0 Aortic (valve) stenosis
0.768 0.232 0.000
X60-X84 Intentional self-harm
0.767 0.233 0.000
I05-I09 Chronic rheumatic heart diseases
0.767 0.233 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.767 0.233 0.000
T66-T78 Other and unspecified effects of external causes
0.762 0.238 0.000
S00.3 Superficial injury of nose
0.761 0.239 0.000
G57 Mononeuropathies of lower limb
0.759 0.241 0.000
D51 Vitamin B12 deficiency anaemia
0.759 0.241 0.000
I78 Diseases of capillaries
0.758 0.242 0.000
I30 Acute pericarditis
0.757 0.243 0.000
M54.1 Radiculopathy
0.757 0.243 0.000
N20-N23 Urolithiasis
0.756 0.244 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.756 0.244 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.756 0.244 0.000
S00.8 Superficial injury of other parts of head
0.755 0.245 0.000
V20-V29 Motorcycle rider injured in transport accident
0.755 0.245 0.000
E22 Hyperfunction of pituitary gland
0.754 0.246 0.000
R56 Convulsions, not elsewhere classified
0.754 0.246 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.754 0.246 0.000
Chapter XIV Diseases of the genitourinary system
0.753 0.247 0.000
R59.0 Localised enlarged lymph nodes
0.752 0.248 0.000
E00-E07 Disorders of thyroid gland
0.751 0.249 0.000
G51 Facial nerve disorders
0.750 0.249 0.000
R61.9 Hyperhidrosis, unspecified
0.749 0.251 0.000
F99-F99 Unspecified mental disorder
0.749 0.251 0.000
M06.0 Seronegative rheumatoid arthritis
0.749 0.251 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.747 0.252 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.747 0.253 0.000
S20-S29 Injuries to the thorax
0.746 0.253 0.000
E86 Volume depletion
0.745 0.255 0.000
M21.0 Valgus deformity, not elsewhere classified
0.744 0.256 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.744 0.256 0.000
I95 Hypotension
0.744 0.256 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.743 0.257 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.743 0.257 0.000
N20 Calculus of kidney and ureter
0.742 0.258 0.000
R52.1 Chronic intractable pain
0.741 0.259 0.000
S72.0 Fracture of neck of femur
0.740 0.260 0.000
E87.6 Hypokalaemia
0.740 0.260 0.000
I81 Portal vein thrombosis
0.740 0.260 0.000
H53-H54 Visual disturbances and blindness
0.739 0.261 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.738 0.262 0.000
F41 Other anxiety disorders
0.738 0.262 0.000
M25.8 Other specified joint disorders
0.736 0.264 0.000
E10.4 With neurological complications
0.736 0.264 0.000
F32.1 Moderate depressive episode
0.736 0.264 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.735 0.265 0.000
G93.9 Disorder of brain, unspecified
0.735 0.265 0.000
F33 Recurrent depressive disorder
0.735 0.265 0.000
S00.9 Superficial injury of head, part unspecified
0.734 0.266 0.000
S80 Superficial injury of lower leg
0.733 0.267 0.000
S00.1 Contusion of eyelid and periocular area
0.733 0.267 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.733 0.267 0.000
N20.1 Calculus of ureter
0.729 0.271 0.000
G54 Nerve root and plexus disorders
0.729 0.271 0.000
M47 Spondylosis
0.729 0.271 0.000
R20 Disturbances of skin sensation
0.729 0.271 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.727 0.272 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.726 0.274 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.725 0.275 0.000
M24 Other specific joint derangements
0.725 0.275 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.724 0.276 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.723 0.277 0.000
W19 Unspecified fall
0.721 0.279 0.000
G30-G32 Other degenerative diseases of the nervous system
0.721 0.279 0.000
M54.29 Cervicalgia-Site unspe
0.720 0.280 0.000
M11 Other crystal arthropathies
0.719 0.281 0.000
R27 Other lack of coordination
0.718 0.282 0.000
I72.4 Aneurysm of artery of lower extremity
0.718 0.282 0.000
R26 Abnormalities of gait and mobility
0.718 0.282 0.000
M05 Seropositive rheumatoid arthritis
0.718 0.282 0.000
G70-G73 Diseases of myoneural junction and muscle
0.718 0.282 0.000
E27 Other disorders of adrenal gland
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
H04.2 Epiphora
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
H04.8 Other disorders of lachrymal system
0.716 0.284 0.000
I51.5 Myocardial degeneration
0.716 0.284 0.000
I51.4 Myocarditis, unspecified
0.716 0.284 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.716 0.284 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.716 0.284 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.716 0.284 0.000
I51.0 Cardiac septal defect, acquired
0.716 0.284 0.000
I72.0 Aneurysm of carotid artery
0.716 0.284 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
S06.3 Focal brain injury
0.715 0.285 0.000
E50-E64 Other nutritional deficiencies
0.714 0.286 0.000
S50-S59 Injuries to the elbow and forearm
0.714 0.286 0.000
M60-M63 Disorders of muscles
0.713 0.286 0.000
M00-M03 Infectious arthropathies
0.713 0.286 0.000
M54.6 Pain in thoracic spine
0.713 0.287 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.713 0.287 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.712 0.287 0.000
H57 Other disorders of eye and adnexa
0.713 0.287 0.000
R50 Fever of unknown origin
0.712 0.288 0.000
E10.1 With ketoacidosis
0.711 0.289 0.000
M84 Disorders of continuity of bone
0.711 0.289 0.000
S90-S99 Injuries to the ankle and foot
0.711 0.289 0.000
T79-T79 Certain early complications of trauma
0.711 0.289 0.000
N21 Calculus of lower urinary tract
0.711 0.289 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.709 0.291 0.000
G93.6 Cerebral oedema
0.708 0.292 0.000
S08 Traumatic amputation of part of head
0.708 0.292 0.000
S07 Crushing injury of head
0.708 0.292 0.000
S04 Injury of cranial nerves
0.708 0.292 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.708 0.292 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.708 0.292 0.000
F38 Other mood [affective] disorders
0.707 0.292 0.000
F34 Persistent mood [affective] disorders
0.707 0.292 0.000
F30 Manic episode
0.707 0.292 0.000
F39 Unspecified mood [affective] disorder
0.707 0.292 0.000
S02 Fracture of skull and facial bones
0.707 0.293 0.000
Chapter XXII Codes for special purposes
0.705 0.294 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.705 0.295 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.704 0.296 0.000
F32.8 Other depressive episodes
0.704 0.296 0.000
F32.0 Mild depressive episode
0.704 0.296 0.000
W20-W49 Exposure to inanimate mechanical forces
0.704 0.296 0.000
R06 Abnormalities of breathing
0.704 0.296 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.703 0.297 0.000
M91-M94 Chondropathies
0.703 0.297 0.000
E78.5 Hyperlipidaemia, unspecified
0.703 0.297 0.000
R45 Symptoms and signs involving emotional state
0.702 0.298 0.000
V80-V89 Other land transport accidents
0.701 0.299 0.000
M25.46 Effusion of joint (Lower leg)
0.701 0.299 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.700 0.300 0.000
I51.7 Cardiomegaly
0.699 0.301 0.000
S42 Fracture of shoulder and upper arm
0.699 0.301 0.000
R68 Other general symptoms and signs
0.696 0.304 0.000
S72.00 Fracture of neck of femur (closed)
0.696 0.304 0.000
E87.2 Acidosis
0.693 0.307 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.692 0.308 0.000
H36 Retinal disorders in diseases classified elsewhere
0.692 0.308 0.000
I42.0 Dilated cardiomyopathy
0.692 0.308 0.000
H55 Nystagmus and other irregular eye movements
0.690 0.310 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.688 0.312 0.000
Y44 Agents primarily affecting blood constituents
0.688 0.312 0.000
I73.8 Other specified peripheral vascular diseases
0.687 0.313 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.687 0.313 0.000
F41.9 Anxiety disorder, unspecified
0.687 0.313 0.000
E46 Unspecified protein-energy malnutrition
0.686 0.314 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.686 0.314 0.000
M67 Other disorders of synovium and tendon
0.684 0.316 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.683 0.317 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.683 0.317 0.000
Y35-Y36 Legal intervention and operations of war
0.683 0.317 0.000
Y10-Y34 Event of undetermined intent
0.683 0.317 0.000
Y00-Y09 Assault
0.683 0.317 0.000
X85-X99 Assault
0.683 0.317 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.683 0.317 0.000
X50-X57 Overexertion, travel and privation
0.683 0.317 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.683 0.317 0.000
X30-X39 Exposure to forces of nature
0.683 0.317 0.000
X20-X29 Contact with venomous animals and plants
0.683 0.317 0.000
X10-X19 Contact with heat and hot substances
0.683 0.317 0.000
X00-X09 Exposure to smoke, fire and flames
0.683 0.317 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.683 0.317 0.000
W75-W84 Other accidental threats to breathing
0.683 0.317 0.000
W65-W74 Accidental drowning and submersion
0.683 0.317 0.000
W50-W64 Exposure to animate mechanical forces
0.683 0.317 0.000
V98-V99 Other and unspecified transport accidents
0.683 0.317 0.000
V95-V97 Air and space transport accidents
0.683 0.317 0.000
V90-V94 Water transport accidents
0.683 0.317 0.000
V70-V79 Bus occupant injured in transport accident
0.683 0.317 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.683 0.317 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.683 0.317 0.000
V40-V49 Car occupant injured in transport accident
0.683 0.317 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.683 0.317 0.000
V01-V09 Pedestrian injured in transport accident
0.683 0.317 0.000
Y52 Agents primarily affecting the cardiovascular system
0.682 0.318 0.000
E34 Other endocrine disorders
0.681 0.319 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.679 0.321 0.000
E65-E68 Obesity and other hyperalimentation
0.679 0.321 0.000
A30-A49 Other bacterial diseases
0.679 0.321 0.000
N21.0 Calculus in bladder
0.678 0.322 0.000
G90 Disorders of autonomic nervous system
0.678 0.322 0.000
I33 Acute and subacute endocarditis
0.678 0.322 0.000
R60 Oedema, not elsewhere classified
0.677 0.323 0.000
S06.2 Diffuse brain injury
0.676 0.324 0.000
S06.4 Epidural haemorrhage
0.676 0.324 0.000
I85 Oesophageal varices
0.676 0.324 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.676 0.324 0.000
S00.7 Multiple superficial injuries of head
0.675 0.325 0.000
S00.5 Superficial injury of lip and oral cavity
0.675 0.325 0.000
S00.4 Superficial injury of ear
0.675 0.325 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.675 0.325 0.000
M53 Other dorsopathies, not elsewhere classified
0.675 0.325 0.000
M47.9 Spondylosis, unspecified
0.675 0.325 0.000
H80-H83 Diseases of inner ear
0.674 0.326 0.000
R06.0 Dyspnoea
0.674 0.326 0.000
I82 Other venous embolism and thrombosis
0.672 0.327 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.672 0.328 0.000
Y57 Other and unspecified drugs and medicaments
0.672 0.328 0.000
E13 Other specified diabetes mellitus
0.671 0.329 0.000
M54.8 Other dorsalgia
0.671 0.329 0.000
M54.0 Panniculitis affecting regions of neck and back
0.671 0.329 0.000
F81 Specific developmental disorders of scholastic skills
0.671 0.329 0.000
H34 Retinal vascular occlusions
0.670 0.330 0.000
G57.6 Lesion of plantar nerve
0.670 0.330 0.000
M79.0 Rheumatism, unspecified
0.669 0.331 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.669 0.331 0.000
G51.0 Bell's palsy
0.669 0.331 0.000
E12 Malnutrition-related diabetes mellitus
0.669 0.331 0.000
S06.5 Traumatic subdural haemorrhage
0.669 0.331 0.000
T86 Failure and rejection of transplanted organs and tissues
0.667 0.333 0.000
N23 Unspecified renal colic
0.667 0.333 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.666 0.333 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.666 0.334 0.000
I99 Other and unspecified disorders of circulatory system
0.665 0.335 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.664 0.335 0.000
M34 Systemic sclerosis
0.664 0.335 0.000
M33 Dermatopolymyositis
0.664 0.335 0.000
M32 Systemic lupus erythematosus
0.664 0.335 0.000
M30 Polyarteritis nodosa and related conditions
0.664 0.335 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.663 0.337 0.000
R12 Heartburn
0.663 0.337 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.662 0.338 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.662 0.338 0.000
I38 Endocarditis, valve unspecified
0.662 0.338 0.000
G50 Disorders of trigeminal nerve
0.662 0.338 0.000
E23 Hypofunction and other disorders of pituitary gland
0.661 0.339 0.000
I45 Other conduction disorders
0.660 0.340 0.000
M14 Arthropathies in other diseases classified elsewhere
0.659 0.341 0.000
M12 Other specific arthropathies
0.659 0.341 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.659 0.341 0.000
M08 Juvenile arthritis
0.659 0.341 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.659 0.341 0.000
R62 Lack of expected normal physiological development
0.659 0.341 0.000
R57 Shock, not elsewhere classified
0.659 0.341 0.000
R64 Cachexia
0.659 0.341 0.000
R58 Haemorrhage, not elsewhere classified
0.659 0.341 0.000
R21 Rash and other nonspecific skin eruption
0.658 0.342 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.658 0.342 0.000
I74.8 Embolism and thrombosis of other arteries
0.658 0.342 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.658 0.342 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.658 0.342 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.658 0.342 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.658 0.342 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.657 0.343 0.000
I95.1 Orthostatic hypotension
0.657 0.343 0.000
S70 Superficial injury of hip and thigh
0.655 0.344 0.000
R25 Abnormal involuntary movements
0.655 0.345 0.000
M25.9 Joint disorder, unspecified
0.655 0.345 0.000
M25.3 Other instability of joint
0.655 0.345 0.000
M25.2 Flail joint
0.655 0.345 0.000
M25.1 Fistula of joint
0.655 0.345 0.000
M25.0 Haemarthrosis
0.655 0.345 0.000
I44 Atrioventricular and left bundle-branch block
0.654 0.346 0.000
E10.8 With unspecified complications
0.653 0.346 0.000
E10.7 With multiple complications
0.653 0.346 0.000
E10.6 With other specified complications
0.653 0.346 0.000
E10.5 With peripheral circulatory complications
0.653 0.346 0.000
E10.2 With renal complications
0.653 0.346 0.000
E10.0 With coma
0.653 0.346 0.000
R52.2 Other chronic pain
0.653 0.347 0.000
R69 Unknown and unspecified causes of morbidity
0.653 0.347 0.000
W19.9 Unspecified place
0.653 0.347 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.652 0.348 0.000
S05.1 Contusion of eyeball and orbital tissues
0.652 0.348 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.652 0.348 0.000
H05 Disorders of orbit
0.652 0.348 0.000
M54.4 Lumbago with sciatica
0.651 0.348 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.650 0.350 0.000
S86 Injury of muscle and tendon at lower leg level
0.650 0.350 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.650 0.350 0.000
S89 Other and unspecified injuries of lower leg
0.649 0.351 0.000
S05.8 Other injuries of eye and orbit
0.648 0.352 0.000
E78.8 Other disorders of lipoprotein metabolism
0.648 0.352 0.000
I47 Paroxysmal tachycardia
0.647 0.353 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.647 0.353 0.000
M85 Other disorders of bone density and structure
0.647 0.353 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.646 0.354 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.646 0.354 0.000
R63 Symptoms and signs concerning food and fluid intake
0.645 0.355 0.000
M21.2 Flexion deformity
0.645 0.355 0.000
W17 Other fall from one level to another
0.645 0.355 0.000
E07 Other disorders of thyroid
0.645 0.355 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.644 0.356 0.000
M54.16 Radiculopathy (Lumbar region)
0.644 0.356 0.000
I46.0 Cardiac arrest with successful resuscitation
0.644 0.356 0.000
R47-R49 Symptoms and signs involving speech and voice
0.643 0.357 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.643 0.357 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.642 0.358 0.000
M54.27 Cervicalgia-Lumbosacral
0.642 0.358 0.000
M54.26 Cervicalgia-Lumbar
0.642 0.358 0.000
M54.25 Cervicalgia-Thoracolumbar
0.642 0.358 0.000
M54.24 Cervicalgia-Thoracic
0.642 0.358 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.642 0.358 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.642 0.358 0.000
M54.20 Cervicalgia-Mult site
0.642 0.358 0.000
T31 Burns classified according to extent of body surface involved
0.641 0.359 0.000
H10-H13 Disorders of conjunctiva
0.641 0.359 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.640 0.359 0.000
M35 Other systemic involvement of connective tissue
0.640 0.360 0.000
S79 Other and unspecified injuries of hip and thigh
0.639 0.361 0.000
H36.0 Diabetic retinopathy
0.638 0.362 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.638 0.362 0.000
R52.0 Acute pain
0.638 0.362 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.638 0.362 0.000
E32 Diseases of thymus
0.638 0.362 0.000
E31 Polyglandular dysfunction
0.638 0.362 0.000
E30 Disorders of puberty, not elsewhere classified
0.638 0.362 0.000
E26 Hyperaldosteronism
0.638 0.362 0.000
E25 Adrenogenital disorders
0.638 0.362 0.000
E24 Cushing's syndrome
0.638 0.362 0.000
E20 Hypoparathyroidism
0.638 0.362 0.000
M25.79 Osteophyte (Site unspecified)
0.638 0.362 0.000
M25.73 Osteophyte (Forearm)
0.638 0.362 0.000
M25.72 Osteophyte (Upper arm)
0.638 0.362 0.000
M25.71 Osteophyte (Shoulder region)
0.638 0.362 0.000
M25.70 Osteophyte (Multiple sites)
0.638 0.362 0.000
S78 Traumatic amputation of hip and thigh
0.637 0.363 0.000
S77 Crushing injury of hip and thigh
0.637 0.363 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.637 0.363 0.000
S75 Injury of blood vessels at hip and thigh level
0.637 0.363 0.000
S74 Injury of nerves at hip and thigh level
0.637 0.363 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.637 0.363 0.000
S71 Open wound of hip and thigh
0.637 0.363 0.000
M10 Gout
0.637 0.363 0.000
E28 Ovarian dysfunction
0.636 0.364 0.000
R56.8 Other and unspecified convulsions
0.636 0.364 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.635 0.365 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.635 0.365 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.634 0.366 0.000
E29 Testicular dysfunction
0.634 0.366 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.632 0.368 0.000
M06.8 Other specified rheumatoid arthritis
0.632 0.368 0.000
M06.4 Inflammatory polyarthropathy
0.632 0.368 0.000
M06.3 Rheumatoid nodule
0.632 0.368 0.000
M06.2 Rheumatoid bursitis
0.632 0.368 0.000
M06.1 Adult-onset Still's disease
0.632 0.368 0.000
S06.0 Concussion
0.632 0.368 0.000
G54.0 Brachial plexus disorders
0.632 0.368 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.632 0.368 0.000
H53 Visual disturbances
0.631 0.369 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.631 0.369 0.000
H60-H62 Diseases of external ear
0.631 0.369 0.000
M80 Osteoporosis with pathological fracture
0.631 0.369 0.000
G91 Hydrocephalus
0.631 0.369 0.000
M47.2 Other spondylosis with radiculopathy
0.631 0.369 0.000
I42.8 Other cardiomyopathies
0.630 0.370 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.630 0.370 0.000
I42.6 Alcoholic cardiomyopathy
0.630 0.370 0.000
I42.5 Other restrictive cardiomyopathy
0.630 0.370 0.000
I42.4 Endocardial fibroelastosis
0.630 0.370 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.630 0.370 0.000
I87 Other disorders of veins
0.630 0.370 0.000
E85 Amyloidosis
0.629 0.371 0.000
E84 Cystic fibrosis
0.629 0.371 0.000
E79 Disorders of purine and pyrimidine metabolism
0.629 0.371 0.000
E77 Disorders of glycoprotein metabolism
0.629 0.371 0.000
E76 Disorders of glycosaminoglycan metabolism
0.629 0.371 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.629 0.371 0.000
E74 Other disorders of carbohydrate metabolism
0.629 0.371 0.000
E73 Lactose intolerance
0.629 0.371 0.000
E72 Other disorders of amino-acid metabolism
0.629 0.371 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.629 0.371 0.000
E70 Disorders of aromatic amino-acid metabolism
0.629 0.371 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.629 0.371 0.000
R27.0 Ataxia, unspecified
0.629 0.371 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.628 0.372 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.628 0.372 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.628 0.372 0.000
W18 Other fall on same level
0.627 0.372 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.627 0.373 0.000
S06.9 Intracranial injury, unspecified
0.625 0.375 0.000
S06.8 Other intracranial injuries
0.625 0.375 0.000
S06.7 Intracranial injury with prolonged coma
0.625 0.375 0.000
S06.1 Traumatic cerebral oedema
0.625 0.375 0.000
G96 Other disorders of central nervous system
0.625 0.375 0.000
V10-V19 Pedal cyclist injured in transport accident
0.625 0.375 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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