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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76744071
log Bayes Factor = 5.63842
Chromosome 4   position 175,950,596  (GRCh37) Explore rs76744071 on Ensembl!
Variant rs76744071 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
K55-K64 Other diseases of intestines
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.994 0.006 0.000
K58 Irritable bowel syndrome
0.990 0.010 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.988 0.012 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.985 0.015 0.000
K57 Diverticular disease of intestine
0.974 0.026 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.963 0.037 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.959 0.041 0.000
Chapter XIV Diseases of the genitourinary system
0.945 0.055 0.000
M20-M25 Other joint disorders
0.938 0.062 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.936 0.064 0.000
Chapter V Mental and behavioural disorders
0.928 0.072 0.000
Y45.0 Opioids and related analgesics
0.926 0.074 0.000
S00-S09 Injuries to the head
0.926 0.074 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.924 0.076 0.000
M25 Other joint disorders, not elsewhere classified
0.923 0.077 0.000
K80 Cholelithiasis
0.920 0.080 0.000
M70-M79 Other soft tissue disorders
0.919 0.081 0.000
N20-N23 Urolithiasis
0.916 0.084 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.914 0.086 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.906 0.094 0.000
M45-M49 Spondylopathies
0.901 0.099 0.000
N20 Calculus of kidney and ureter
0.898 0.102 0.000
M40-M43 Deforming dorsopathies
0.894 0.105 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.892 0.108 0.000
S20-S29 Injuries to the thorax
0.889 0.111 0.000
M25.5 Pain in joint
0.885 0.115 0.000
K35-K38 Diseases of appendix
0.880 0.120 0.000
Chapter II Neoplasms
0.878 0.122 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.877 0.123 0.000
S01 Open wound of head
0.872 0.128 0.000
F30-F39 Mood [affective] disorders
0.871 0.129 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.867 0.133 0.000
M25.56 Pain in joint (Lower leg)
0.861 0.139 0.000
K60 Fissure and fistula of anal and rectal regions
0.857 0.143 0.000
K57.2 Diverticular disease of large intestine with perforation and abscess
0.851 0.149 0.000
M80-M85 Disorders of bone density and structure
0.848 0.152 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.843 0.157 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.838 0.162 0.000
N73 Other female pelvic inflammatory diseases
0.837 0.163 0.000
D00-D09 In situ neoplasms
0.835 0.165 0.000
M79.0 Rheumatism, unspecified
0.835 0.165 0.000
N75 Diseases of Bartholin's gland
0.832 0.168 0.000
S40-S49 Injuries to the shoulder and upper arm
0.832 0.168 0.000
N20.0 Calculus of kidney
0.831 0.169 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.826 0.174 0.000
T66-T78 Other and unspecified effects of external causes
0.824 0.176 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.821 0.179 0.000
Y95 Nosocomial condition
0.819 0.181 0.000
K82 Other diseases of gallbladder
0.819 0.181 0.000
M79.6 Pain in limb
0.816 0.184 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.815 0.185 0.000
K81 Cholecystitis
0.814 0.186 0.000
F32 Depressive episode
0.811 0.189 0.000
S01.8 Open wound of other parts of head
0.810 0.190 0.000
N17-N19 Renal failure
0.809 0.191 0.000
K50-K52 Noninfective enteritis and colitis
0.808 0.192 0.000
Chapter I Certain infectious and parasitic diseases
0.806 0.194 0.000
N20.1 Calculus of ureter
0.802 0.198 0.000
C79 Secondary malignant neoplasm of other sites
0.799 0.201 0.000
Y44 Agents primarily affecting blood constituents
0.798 0.202 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.798 0.202 0.000
M25.7 Osteophyte
0.797 0.203 0.000
Y43 Primarily systemic agents
0.791 0.209 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.791 0.209 0.000
N99-N99 Other disorders of the genitourinary system
0.790 0.210 0.000
M22 Disorders of patella
0.789 0.211 0.000
M43 Other deforming dorsopathies
0.788 0.212 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.788 0.212 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.787 0.213 0.000
N73.6 Female pelvic peritoneal adhesions
0.786 0.214 0.000
N75.0 Cyst of Bartholin's gland
0.784 0.216 0.000
Y40 Systemic antibiotics
0.779 0.221 0.000
M79.1 Myalgia
0.778 0.222 0.000
S80-S89 Injuries to the knee and lower leg
0.776 0.224 0.000
F32.9 Depressive episode, unspecified
0.775 0.225 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.774 0.226 0.000
K62 Other diseases of anus and rectum
0.773 0.227 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.773 0.227 0.000
M60-M63 Disorders of muscles
0.771 0.229 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.769 0.231 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.767 0.233 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.766 0.234 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.764 0.236 0.000
M46 Other inflammatory spondylopathies
0.761 0.239 0.000
K51 Ulcerative colitis
0.761 0.239 0.000
M91-M94 Chondropathies
0.760 0.240 0.000
D05 Carcinoma in situ of breast
0.758 0.242 0.000
D06 Carcinoma in situ of cervix uteri
0.756 0.244 0.000
S90-S99 Injuries to the ankle and foot
0.755 0.245 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.755 0.245 0.000
K35 Acute appendicitis
0.754 0.246 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.754 0.246 0.000
V80-V89 Other land transport accidents
0.751 0.249 0.000
M50-M54 Other dorsopathies
0.750 0.250 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.749 0.251 0.000
M86-M90 Other osteopathies
0.745 0.254 0.000
Chapter VIII Diseases of the ear and mastoid process
0.742 0.258 0.000
R07 Pain in throat and chest
0.741 0.259 0.000
R07.4 Chest pain, unspecified
0.741 0.259 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.741 0.259 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.740 0.260 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.738 0.262 0.000
S05 Injury of eye and orbit
0.737 0.263 0.000
T79-T79 Certain early complications of trauma
0.736 0.264 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.736 0.264 0.000
Y57 Other and unspecified drugs and medicaments
0.735 0.265 0.000
N19 Unspecified renal failure
0.735 0.265 0.000
K60.2 Anal fissure, unspecified
0.734 0.266 0.000
N70 Salpingitis and oophoritis
0.733 0.267 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.733 0.267 0.000
M31 Other necrotising vasculopathies
0.732 0.268 0.000
S02 Fracture of skull and facial bones
0.731 0.269 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.730 0.270 0.000
V20-V29 Motorcycle rider injured in transport accident
0.730 0.270 0.000
Y52 Agents primarily affecting the cardiovascular system
0.729 0.271 0.000
M47 Spondylosis
0.727 0.273 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.727 0.273 0.000
N72 Inflammatory disease of cervix uteri
0.727 0.273 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.726 0.274 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.726 0.274 0.000
M79.7 Fibromyalgia
0.725 0.275 0.000
K51.9 Ulcerative colitis, unspecified
0.725 0.275 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.724 0.276 0.000
R00 Abnormalities of heart beat
0.724 0.276 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.723 0.277 0.000
V10-V19 Pedal cyclist injured in transport accident
0.722 0.278 0.000
K38 Other diseases of appendix
0.722 0.278 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.722 0.278 0.000
M25.8 Other specified joint disorders
0.721 0.278 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.721 0.279 0.000
M79.64 Pain in limb (Hand)
0.720 0.280 0.000
M81 Osteoporosis without pathological fracture
0.720 0.280 0.000
K56.6 Other and unspecified intestinal obstruction
0.720 0.280 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.718 0.282 0.000
M41 Scoliosis
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M65-M68 Disorders of synovium and tendon
0.716 0.284 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
M45 Ankylosing spondylitis
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.715 0.284 0.000
N20.9 Urinary calculus, unspecified
0.714 0.286 0.000
K70-K77 Diseases of liver
0.713 0.287 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.713 0.287 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.712 0.287 0.000
Y35-Y36 Legal intervention and operations of war
0.712 0.287 0.000
Y10-Y34 Event of undetermined intent
0.712 0.287 0.000
Y00-Y09 Assault
0.712 0.287 0.000
X85-X99 Assault
0.712 0.287 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.712 0.287 0.000
X50-X57 Overexertion, travel and privation
0.712 0.287 0.000
X30-X39 Exposure to forces of nature
0.712 0.287 0.000
X20-X29 Contact with venomous animals and plants
0.712 0.287 0.000
X10-X19 Contact with heat and hot substances
0.712 0.287 0.000
X00-X09 Exposure to smoke, fire and flames
0.712 0.287 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.712 0.287 0.000
W75-W84 Other accidental threats to breathing
0.712 0.287 0.000
W65-W74 Accidental drowning and submersion
0.712 0.287 0.000
W50-W64 Exposure to animate mechanical forces
0.712 0.287 0.000
V98-V99 Other and unspecified transport accidents
0.712 0.287 0.000
V95-V97 Air and space transport accidents
0.712 0.287 0.000
V90-V94 Water transport accidents
0.712 0.287 0.000
V70-V79 Bus occupant injured in transport accident
0.712 0.287 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.712 0.287 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.712 0.287 0.000
V40-V49 Car occupant injured in transport accident
0.712 0.287 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.712 0.287 0.000
V01-V09 Pedestrian injured in transport accident
0.712 0.287 0.000
Chapter VI Diseases of the nervous system
0.712 0.288 0.000
M43.1 Spondylolisthesis
0.712 0.288 0.000
N20.2 Calculus of kidney with calculus of ureter
0.712 0.288 0.000
R00.1 Bradycardia, unspecified
0.712 0.288 0.000
K81.9 Cholecystitis, unspecified
0.709 0.291 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.709 0.291 0.000
Y59 Other and unspecified vaccines and biological substances
0.708 0.291 0.000
Y58 Bacterial vaccines
0.708 0.291 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.708 0.291 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.708 0.291 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.708 0.291 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.708 0.291 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.708 0.291 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.708 0.291 0.000
Y48 Anaesthetics and therapeutic gases
0.708 0.291 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.708 0.291 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.708 0.291 0.000
S01.5 Open wound of lip and oral cavity
0.707 0.293 0.000
S29 Other and unspecified injuries of thorax
0.706 0.294 0.000
X60-X84 Intentional self-harm
0.705 0.295 0.000
W20-W49 Exposure to inanimate mechanical forces
0.705 0.295 0.000
K29.7 Gastritis, unspecified
0.704 0.296 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.703 0.297 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.703 0.297 0.000
S01.2 Open wound of nose
0.701 0.299 0.000
K29 Gastritis and duodenitis
0.701 0.299 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.700 0.300 0.000
T78 Adverse effects, not elsewhere classified
0.699 0.301 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.699 0.301 0.000
D06.9 Cervix, unspecified
0.699 0.301 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.699 0.301 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.699 0.301 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.699 0.301 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.699 0.301 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.698 0.302 0.000
K80.8 Other cholelithiasis
0.698 0.302 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.698 0.302 0.000
M24 Other specific joint derangements
0.697 0.303 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.696 0.304 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.695 0.305 0.000
M25.52 Pain in joint (Upper arm)
0.694 0.306 0.000
M79.60 Pain in limb (Multiple sites)
0.693 0.307 0.000
N23 Unspecified renal colic
0.693 0.307 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.693 0.307 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.692 0.308 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.690 0.310 0.000
Y45.8 Other analgesics and antipyretics
0.690 0.310 0.000
Y45.5 4-Aminophenol derivatives
0.690 0.310 0.000
Y45.4 Antirheumatics
0.690 0.310 0.000
Y45.2 Propionic acid derivatives
0.690 0.310 0.000
Y45.1 Salicylates
0.690 0.310 0.000
K60.5 Anorectal fistula
0.690 0.310 0.000
B95-B98 Bacterial, viral and other infectious agents
0.688 0.312 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.688 0.312 0.000
K85 Acute pancreatitis
0.688 0.312 0.000
Chapter XXII Codes for special purposes
0.684 0.315 0.000
K80.4 Calculus of bile duct with cholecystitis
0.683 0.317 0.000
S50-S59 Injuries to the elbow and forearm
0.682 0.318 0.000
N25-N29 Other disorders of kidney and ureter
0.680 0.320 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.680 0.320 0.000
F31 Bipolar affective disorder
0.679 0.321 0.000
K60.0 Acute anal fissure
0.678 0.322 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.677 0.322 0.000
K62.6 Ulcer of anus and rectum
0.677 0.323 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.677 0.323 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.676 0.323 0.000
C64-C68 Malignant neoplasms of urinary tract
0.676 0.324 0.000
S01.4 Open wound of cheek and temporomandibular area
0.675 0.325 0.000
K82.9 Disease of gallbladder, unspecified
0.675 0.325 0.000
N76 Other inflammation of vagina and vulva
0.674 0.325 0.000
M25.59 Pain in joint (Site unspecified)
0.674 0.326 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.673 0.327 0.000
T98 Sequelae of other and unspecified effects of external causes
0.673 0.327 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.673 0.327 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.673 0.327 0.000
M34 Systemic sclerosis
0.673 0.327 0.000
M33 Dermatopolymyositis
0.673 0.327 0.000
M32 Systemic lupus erythematosus
0.673 0.327 0.000
M30 Polyarteritis nodosa and related conditions
0.673 0.327 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.673 0.327 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.672 0.328 0.000
S22.3 Fracture of rib
0.672 0.328 0.000
F80-F89 Disorders of psychological development
0.670 0.330 0.000
Y43.4 Immunosuppressive agents
0.667 0.333 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.667 0.333 0.000
F99-F99 Unspecified mental disorder
0.667 0.333 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.666 0.334 0.000
F70-F79 Mental retardation
0.666 0.334 0.000
F60-F69 Disorders of adult personality and behaviour
0.666 0.334 0.000
K35.0 Acute appendicitis with generalised peritonitis
0.665 0.335 0.000
S08 Traumatic amputation of part of head
0.664 0.336 0.000
S07 Crushing injury of head
0.664 0.336 0.000
S04 Injury of cranial nerves
0.664 0.336 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.664 0.336 0.000
M21 Other acquired deformities of limbs
0.664 0.336 0.000
C77.3 Axillary and upper limb lymph nodes
0.663 0.337 0.000
Y44.2 Anticoagulants
0.662 0.338 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.662 0.338 0.000
N71 Inflammatory disease of uterus, except cervix
0.662 0.338 0.000
M25.9 Joint disorder, unspecified
0.662 0.338 0.000
M25.3 Other instability of joint
0.662 0.338 0.000
M25.2 Flail joint
0.662 0.338 0.000
M25.1 Fistula of joint
0.662 0.338 0.000
M25.0 Haemarthrosis
0.662 0.338 0.000
S06 Intracranial injury
0.662 0.338 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.662 0.338 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.662 0.338 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.661 0.339 0.000
T40.2 Other opioids
0.660 0.340 0.000
K80.3 Calculus of bile duct with cholangitis
0.659 0.341 0.000
M85 Other disorders of bone density and structure
0.659 0.341 0.000
M76 Enthesopathies of lower limb, excluding foot
0.659 0.341 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.659 0.341 0.000
M71 Other bursopathies
0.659 0.341 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.658 0.341 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.658 0.342 0.000
M47.9 Spondylosis, unspecified
0.658 0.342 0.000
K81.1 Chronic cholecystitis
0.658 0.342 0.000
S81 Open wound of lower leg
0.657 0.343 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.657 0.343 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.657 0.343 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.656 0.344 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.656 0.344 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.656 0.344 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.656 0.344 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.656 0.344 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.656 0.344 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.656 0.344 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.656 0.344 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.656 0.344 0.000
T36 Poisoning by systemic antibiotics
0.656 0.344 0.000
F33 Recurrent depressive disorder
0.655 0.345 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.652 0.348 0.000
M22.4 Chondromalacia patellae
0.652 0.348 0.000
K58.0 Irritable bowel syndrome with diarrhoea
0.650 0.350 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.650 0.350 0.000
M79.9 Soft tissue disorder, unspecified
0.650 0.350 0.000
M79.5 Residual foreign body in soft tissue
0.650 0.350 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.650 0.350 0.000
M79.3 Panniculitis, unspecified
0.650 0.350 0.000
M79.2 Neuralgia and neuritis, unspecified
0.650 0.350 0.000
K40-K46 Hernia
0.649 0.351 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.648 0.352 0.000
D80-D89 Certain disorders involving the immune mechanism
0.648 0.352 0.000
K56.2 Volvulus
0.646 0.354 0.000
M49 Spondylopathies in diseases classified elsewhere
0.646 0.354 0.000
M48 Other spondylopathies
0.646 0.354 0.000
M79.10 Myalgia (Multiple sites)
0.645 0.355 0.000
K56.7 Ileus, unspecified
0.644 0.355 0.000
S22.0 Fracture of thoracic vertebra
0.644 0.356 0.000
S20 Superficial injury of thorax
0.643 0.357 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.643 0.357 0.000
M25.57 Pain in joint (Ankle and foot)
0.642 0.358 0.000
M25.51 Pain in joint (Shoulder region)
0.641 0.358 0.000
M42 Spinal osteochondrosis
0.641 0.359 0.000
M40 Kyphosis and lordosis
0.641 0.359 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.641 0.359 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.641 0.359 0.000
B50-B64 Protozoal diseases
0.640 0.360 0.000
F43 Reaction to severe stress, and adjustment disorders
0.640 0.360 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.639 0.360 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.639 0.360 0.000
Y98 Lifestyle-related condition
0.639 0.360 0.000
Y97 Environmental-pollution-related condition
0.639 0.360 0.000
Y96 Work-related condition
0.639 0.360 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.637 0.363 0.000
S26 Injury of heart
0.637 0.363 0.000
S25 Injury of blood vessels of thorax
0.637 0.363 0.000
S24 Injury of nerves and spinal cord at thorax level
0.637 0.363 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.637 0.363 0.000
S21 Open wound of thorax
0.637 0.363 0.000
S43.0 Dislocation of shoulder joint
0.637 0.363 0.000
M22.8 Other disorders of patella
0.637 0.363 0.000
M25.76 Osteophyte (Lower leg)
0.635 0.365 0.000
M25.58 Pain in joint (Other)
0.634 0.365 0.000
N17 Acute renal failure
0.634 0.366 0.000
S22.5 Flail chest
0.633 0.367 0.000
D05.1 Intraductal carcinoma in situ
0.633 0.367 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.632 0.367 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.632 0.368 0.000
C51-C58 Malignant neoplasms of female genital organs
0.631 0.369 0.000
K36 Other appendicitis
0.631 0.369 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.629 0.371 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.629 0.371 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.629 0.371 0.000
T87 Complications peculiar to reattachment and amputation
0.629 0.371 0.000
T86 Failure and rejection of transplanted organs and tissues
0.629 0.371 0.000
M81.9 Osteoporosis, unspecified
0.628 0.372 0.000
M79.62 Pain in limb (Upper arm)
0.627 0.373 0.000
M79.19 Myalgia (Site unspecified)
0.627 0.373 0.000
N00-N08 Glomerular diseases
0.626 0.373 0.000
K62.3 Rectal prolapse
0.626 0.374 0.000
T78.2 Anaphylactic shock, unspecified
0.626 0.374 0.000
S01.7 Multiple open wounds of head
0.625 0.375 0.000
S01.3 Open wound of ear
0.625 0.375 0.000
S70-S79 Injuries to the hip and thigh
0.625 0.375 0.000
H60-H62 Diseases of external ear
0.625 0.375 0.000
F38 Other mood [affective] disorders
0.625 0.375 0.000
F34 Persistent mood [affective] disorders
0.625 0.375 0.000
F30 Manic episode
0.625 0.375 0.000
F39 Unspecified mood [affective] disorder
0.625 0.375 0.000
K82.1 Hydrops of gallbladder
0.625 0.375 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.624 0.376 0.000
M50 Cervical disk disorders
0.624 0.376 0.000
K82.4 Cholesterolosis of gallbladder
0.624 0.376 0.000
M84 Disorders of continuity of bone
0.622 0.378 0.000
K56.4 Other impaction of intestine
0.621 0.379 0.000
K56.3 Gallstone ileus
0.621 0.379 0.000
K56.1 Intussusception
0.621 0.379 0.000
K56.0 Paralytic ileus
0.621 0.379 0.000
T82.3 Mechanical complication of other vascular grafts
0.621 0.379 0.000
K01 Embedded and impacted teeth
0.621 0.379 0.000
M79.8 Other specified soft tissue disorders
0.621 0.379 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.620 0.379 0.000
K29.3 Chronic superficial gastritis
0.620 0.380 0.000
K60.1 Chronic anal fissure
0.619 0.381 0.000
M77 Other enthesopathies
0.618 0.381 0.000
R07.0 Pain in throat
0.618 0.382 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.617 0.382 0.000
K35.9 Acute appendicitis, unspecified
0.618 0.382 0.000
D03 Melanoma in situ
0.617 0.383 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.616 0.384 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.616 0.384 0.000
Chapter VII Diseases of the eye and adnexa
0.615 0.385 0.000
K60.4 Rectal fistula
0.615 0.385 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.614 0.386 0.000
S01.9 Open wound of head, part unspecified
0.614 0.386 0.000
M25.4 Effusion of joint
0.614 0.386 0.000
S27 Injury of other and unspecified intrathoracic organs
0.613 0.387 0.000
T92 Sequelae of injuries of upper limb
0.613 0.387 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.612 0.388 0.000
K37 Unspecified appendicitis
0.611 0.389 0.000
Y40.0 Penicillins
0.610 0.390 0.000
W00-W19 Falls
0.609 0.390 0.000
C77.0 Lymph nodes of head, face and neck
0.609 0.391 0.000
K38.8 Other specified diseases of appendix
0.609 0.391 0.000
M62 Other disorders of muscle
0.609 0.391 0.000
M83 Adult osteomalacia
0.608 0.392 0.000
M82 Osteoporosis in diseases classified elsewhere
0.608 0.392 0.000
K62.8 Other specified diseases of anus and rectum
0.608 0.392 0.000
C50-C50 Malignant neoplasm of breast
0.607 0.393 0.000
R07.2 Precordial pain
0.605 0.395 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.604 0.396 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.604 0.396 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.604 0.396 0.000
K13 Other diseases of lip and oral mucosa
0.603 0.397 0.000
K12 Stomatitis and related lesions
0.603 0.397 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.603 0.397 0.000
G90-G99 Other disorders of the nervous system
0.603 0.397 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.602 0.398 0.000
K59 Other functional intestinal disorders
0.602 0.398 0.000
M99 Biomechanical lesions, not elsewhere classified
0.601 0.399 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.601 0.399 0.000
B35-B49 Mycoses
0.601 0.399 0.000
H80-H83 Diseases of inner ear
0.600 0.400 0.000
N73.8 Other specified female pelvic inflammatory diseases
0.600 0.400 0.000
N73.5 Female pelvic peritonitis, unspecified
0.600 0.400 0.000
N73.4 Female chronic pelvic peritonitis
0.600 0.400 0.000
N73.3 Female acute pelvic peritonitis
0.600 0.400 0.000
N73.2 Unspecified parametritis and pelvic cellulitis
0.600 0.400 0.000
N73.1 Chronic parametritis and pelvic cellulitis
0.600 0.400 0.000
N73.0 Acute parametritis and pelvic cellulitis
0.600 0.400 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.600 0.400 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.599 0.401 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.599 0.401 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.599 0.401 0.000
M79.08 Rheumatism, unspecified (Other)
0.599 0.401 0.000
M79.07 Rheumatism, unspecified (Ankle and foot)
0.599 0.401 0.000
M79.06 Rheumatism, unspecified (Lower leg)
0.599 0.401 0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.599 0.401 0.000
M79.04 Rheumatism, unspecified (Hand)
0.599 0.401 0.000
M79.03 Rheumatism, unspecified (Forearm)
0.599 0.401 0.000
M79.02 Rheumatism, unspecified (Upper arm)
0.599 0.401 0.000
M79.01 Rheumatism, unspecified (Shoulder region)
0.599 0.401 0.000
M79.67 Pain in limb (Ankle and foot)
0.598 0.402 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.598 0.402 0.000
N75.9 Disease of Bartholin's gland, unspecified
0.597 0.403 0.000
N75.8 Other diseases of Bartholin's gland
0.597 0.403 0.000
M25.54 Pain in joint (Hand)
0.597 0.403 0.000
N70.1 Chronic salpingitis and oophoritis
0.597 0.403 0.000
S48 Traumatic amputation of shoulder and upper arm
0.596 0.403 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.596 0.403 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.596 0.403 0.000
S44 Injury of nerves at shoulder and upper arm level
0.596 0.403 0.000
S41 Open wound of shoulder and upper arm
0.596 0.403 0.000
S40 Superficial injury of shoulder and upper arm
0.596 0.403 0.000
S47 Crushing injury of shoulder and upper arm
0.596 0.403 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.596 0.404 0.000
M79.79 Fibromyalgia (Site unspecified)
0.596 0.404 0.000
S02.3 Fracture of orbital floor
0.596 0.404 0.000
S60-S69 Injuries to the wrist and hand
0.592 0.408 0.000
M41.9 Scoliosis, unspecified
0.592 0.408 0.000
T75 Effects of other external causes
0.591 0.409 0.000
T74 Maltreatment syndromes
0.591 0.409 0.000
T73 Effects of other deprivation
0.591 0.409 0.000
T70 Effects of air pressure and water pressure
0.591 0.409 0.000
T69 Other effects of reduced temperature
0.591 0.409 0.000
T67 Effects of heat and light
0.591 0.409 0.000
T71 Asphyxiation
0.591 0.409 0.000
T68 Hypothermia
0.591 0.409 0.000
T66 Unspecified effects of radiation
0.591 0.409 0.000
D04 Carcinoma in situ of skin
0.591 0.409 0.000
Q50-Q56 Congenital malformations of genital organs
0.591 0.409 0.000
K82.8 Other specified diseases of gallbladder
0.589 0.411 0.000
M94 Other disorders of cartilage
0.589 0.411 0.000
S22.30 Fracture of rib (closed)
0.589 0.411 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.588 0.412 0.000
K51.4 Pseudopolyposis of colon
0.587 0.413 0.000
K82.3 Fistula of gallbladder
0.587 0.413 0.000
K82.2 Perforation of gallbladder
0.587 0.413 0.000
K82.0 Obstruction of gallbladder
0.587 0.413 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.587 0.413 0.000
S99 Other and unspecified injuries of ankle and foot
0.585 0.414 0.000
K61 Abscess of anal and rectal regions
0.585 0.414 0.000
K74 Fibrosis and cirrhosis of liver
0.585 0.415 0.000
M79.68 Pain in limb (Other)
0.585 0.415 0.000
M79.63 Pain in limb (Forearm)
0.585 0.415 0.000
M79.61 Pain in limb (Shoulder region)
0.585 0.415 0.000
T95 Sequelae of burns, corrosions and frostbite
0.584 0.415 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.584 0.415 0.000
T91 Sequelae of injuries of neck and trunk
0.584 0.415 0.000
T90 Sequelae of injuries of head
0.584 0.415 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.584 0.415 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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