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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76759221
log Bayes Factor = 2.08624
Chromosome 1   position 239,716,845  (GRCh37) Explore rs76759221 on Ensembl!
Variant rs76759221 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.991 0.009 0.000
Chapter X Diseases of the respiratory system
0.990 0.010 0.000
J40-J47 Chronic lower respiratory diseases
0.989 0.011 0.000
Chapter II Neoplasms
0.983 0.017 0.000
J44 Other chronic obstructive pulmonary disease
0.972 0.028 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.959 0.041 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.956 0.044 0.000
Chapter XI Diseases of the digestive system
0.954 0.046 0.000
Chapter XX External causes of morbidity and mortality
0.943 0.057 0.000
C15-C26 Malignant neoplasms of digestive organs
0.929 0.071 0.000
J47 Bronchiectasis
0.924 0.076 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.909 0.091 0.000
K90-K93 Other diseases of the digestive system
0.904 0.096 0.000
Chapter I Certain infectious and parasitic diseases
0.899 0.101 0.000
J45 Asthma
0.895 0.105 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.884 0.116 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.867 0.133 0.000
Chapter VI Diseases of the nervous system
0.867 0.133 0.000
J09-J18 Influenza and pneumonia
0.864 0.136 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.851 0.149 0.000
S20-S29 Injuries to the thorax
0.850 0.149 0.000
K50-K52 Noninfective enteritis and colitis
0.850 0.150 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.843 0.157 0.000
S60-S69 Injuries to the wrist and hand
0.842 0.158 0.000
J30-J39 Other diseases of upper respiratory tract
0.840 0.160 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.837 0.163 0.000
K92 Other diseases of digestive system
0.837 0.163 0.000
C15 Malignant neoplasm of oesophagus
0.828 0.172 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.823 0.177 0.000
S50-S59 Injuries to the elbow and forearm
0.823 0.177 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.821 0.179 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.818 0.182 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.815 0.185 0.000
K65-K67 Diseases of peritoneum
0.813 0.187 0.000
C79 Secondary malignant neoplasm of other sites
0.810 0.190 0.000
J45.9 Asthma, unspecified
0.808 0.192 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.804 0.196 0.000
C50-C50 Malignant neoplasm of breast
0.804 0.196 0.000
K70-K77 Diseases of liver
0.793 0.207 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.792 0.208 0.000
J42 Unspecified chronic bronchitis
0.781 0.219 0.000
J46 Status asthmaticus
0.779 0.221 0.000
A00-A09 Intestinal infectious diseases
0.778 0.222 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.776 0.224 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.775 0.225 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.774 0.226 0.000
J18 Pneumonia, organism unspecified
0.773 0.227 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.771 0.229 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.767 0.233 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.767 0.233 0.000
C16 Malignant neoplasm of stomach
0.766 0.234 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.764 0.236 0.000
S70-S79 Injuries to the hip and thigh
0.764 0.236 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.761 0.239 0.000
G56 Mononeuropathies of upper limb
0.756 0.244 0.000
C77.9 Lymph node, unspecified
0.752 0.248 0.000
J95-J99 Other diseases of the respiratory system
0.748 0.252 0.000
C64-C68 Malignant neoplasms of urinary tract
0.747 0.253 0.000
Chapter VIII Diseases of the ear and mastoid process
0.742 0.258 0.000
K50 Crohn's disease [regional enteritis]
0.742 0.258 0.000
C25 Malignant neoplasm of pancreas
0.735 0.265 0.000
Y86 Sequelae of other accidents
0.734 0.266 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.731 0.269 0.000
S52 Fracture of forearm
0.727 0.273 0.000
J90-J94 Other diseases of pleura
0.725 0.275 0.000
Chapter XXII Codes for special purposes
0.725 0.275 0.000
C18 Malignant neoplasm of colon
0.722 0.278 0.000
W20-W49 Exposure to inanimate mechanical forces
0.719 0.281 0.000
J60-J70 Lung diseases due to external agents
0.719 0.281 0.000
B95-B98 Bacterial, viral and other infectious agents
0.715 0.285 0.000
C77.3 Axillary and upper limb lymph nodes
0.715 0.285 0.000
C51-C58 Malignant neoplasms of female genital organs
0.714 0.286 0.000
K65 Peritonitis
0.713 0.287 0.000
J40 Bronchitis, not specified as acute or chronic
0.712 0.288 0.000
B35-B49 Mycoses
0.711 0.289 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.710 0.289 0.000
W00-W19 Falls
0.710 0.290 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.710 0.290 0.000
M80-M85 Disorders of bone density and structure
0.710 0.290 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.710 0.290 0.000
J41 Simple and mucopurulent chronic bronchitis
0.709 0.291 0.000
S00-S09 Injuries to the head
0.709 0.291 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.705 0.295 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.705 0.295 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.705 0.295 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.705 0.295 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.705 0.295 0.000
J18.1 Lobar pneumonia, unspecified
0.705 0.295 0.000
C80 Malignant neoplasm without specification of site
0.704 0.295 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.703 0.296 0.000
C15.9 Oesophagus, unspecified
0.702 0.297 0.000
C78.0 Secondary malignant neoplasm of lung
0.702 0.298 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.702 0.298 0.000
K35-K38 Diseases of appendix
0.701 0.299 0.000
D00-D09 In situ neoplasms
0.700 0.300 0.000
K90 Intestinal malabsorption
0.699 0.301 0.000
J45.0 Predominantly allergic asthma
0.699 0.301 0.000
X60-X84 Intentional self-harm
0.696 0.304 0.000
G56.0 Carpal tunnel syndrome
0.696 0.304 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.696 0.304 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.696 0.304 0.000
C15.5 Lower third of oesophagus
0.692 0.308 0.000
C78.2 Secondary malignant neoplasm of pleura
0.692 0.308 0.000
S90-S99 Injuries to the ankle and foot
0.691 0.309 0.000
K02 Dental caries
0.689 0.311 0.000
S62 Fracture at wrist and hand level
0.687 0.312 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.687 0.312 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.686 0.314 0.000
T79-T79 Certain early complications of trauma
0.686 0.314 0.000
T66-T78 Other and unspecified effects of external causes
0.686 0.314 0.000
T33-T35 Frostbite
0.686 0.314 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.686 0.314 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.686 0.314 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.686 0.314 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.686 0.314 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.686 0.314 0.000
T00-T07 Injuries involving multiple body regions
0.686 0.314 0.000
S10-S19 Injuries to the neck
0.686 0.314 0.000
K92.1 Melaena
0.684 0.316 0.000
J33 Nasal polyp
0.684 0.316 0.000
J35 Chronic diseases of tonsils and adenoids
0.683 0.317 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.679 0.321 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.676 0.324 0.000
Y35-Y36 Legal intervention and operations of war
0.676 0.324 0.000
Y10-Y34 Event of undetermined intent
0.676 0.324 0.000
Y00-Y09 Assault
0.676 0.324 0.000
X85-X99 Assault
0.676 0.324 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.676 0.324 0.000
X50-X57 Overexertion, travel and privation
0.676 0.324 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.676 0.324 0.000
X30-X39 Exposure to forces of nature
0.676 0.324 0.000
X20-X29 Contact with venomous animals and plants
0.676 0.324 0.000
X10-X19 Contact with heat and hot substances
0.676 0.324 0.000
X00-X09 Exposure to smoke, fire and flames
0.676 0.324 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.676 0.324 0.000
W75-W84 Other accidental threats to breathing
0.676 0.324 0.000
W65-W74 Accidental drowning and submersion
0.676 0.324 0.000
W50-W64 Exposure to animate mechanical forces
0.676 0.324 0.000
V98-V99 Other and unspecified transport accidents
0.676 0.324 0.000
V95-V97 Air and space transport accidents
0.676 0.324 0.000
V90-V94 Water transport accidents
0.676 0.324 0.000
V80-V89 Other land transport accidents
0.676 0.324 0.000
V70-V79 Bus occupant injured in transport accident
0.676 0.324 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.676 0.324 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.676 0.324 0.000
V40-V49 Car occupant injured in transport accident
0.676 0.324 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.676 0.324 0.000
V20-V29 Motorcycle rider injured in transport accident
0.676 0.324 0.000
V01-V09 Pedestrian injured in transport accident
0.676 0.324 0.000
C50 Malignant neoplasm of breast
0.676 0.324 0.000
G20-G26 Extrapyramidal and movement disorders
0.675 0.325 0.000
V10-V19 Pedal cyclist injured in transport accident
0.673 0.326 0.000
S80-S89 Injuries to the knee and lower leg
0.673 0.327 0.000
S22.4 Multiple fractures of ribs
0.673 0.327 0.000
K55-K64 Other diseases of intestines
0.672 0.328 0.000
S40-S49 Injuries to the shoulder and upper arm
0.672 0.328 0.000
G30-G32 Other degenerative diseases of the nervous system
0.670 0.330 0.000
K51 Ulcerative colitis
0.667 0.332 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.666 0.334 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.666 0.334 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.666 0.334 0.000
C21 Malignant neoplasm of anus and anal canal
0.666 0.334 0.000
C17 Malignant neoplasm of small intestine
0.666 0.334 0.000
C23 Malignant neoplasm of gallbladder
0.666 0.334 0.000
C20 Malignant neoplasm of rectum
0.666 0.334 0.000
G56.2 Lesion of ulnar nerve
0.665 0.335 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.663 0.337 0.000
D10-D36 Benign neoplasms
0.661 0.339 0.000
D70 Agranulocytosis
0.660 0.340 0.000
C78.7 Secondary malignant neoplasm of liver
0.660 0.340 0.000
D80-D89 Certain disorders involving the immune mechanism
0.658 0.342 0.000
K70 Alcoholic liver disease
0.657 0.343 0.000
S61 Open wound of wrist and hand
0.657 0.343 0.000
Q60-Q64 Congenital malformations of the urinary system
0.657 0.343 0.000
K11 Diseases of salivary glands
0.657 0.343 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.654 0.346 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.654 0.346 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.651 0.349 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.648 0.351 0.000
Y43 Primarily systemic agents
0.648 0.351 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.648 0.352 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.647 0.353 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.647 0.353 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.645 0.355 0.000
B99-B99 Other infectious diseases
0.644 0.356 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.644 0.356 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.644 0.356 0.000
B65-B83 Helminthiases
0.644 0.356 0.000
B50-B64 Protozoal diseases
0.644 0.356 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.644 0.356 0.000
B15-B19 Viral hepatitis
0.644 0.356 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.644 0.356 0.000
A80-A89 Viral infections of the central nervous system
0.644 0.356 0.000
A75-A79 Rickettsioses
0.644 0.356 0.000
A70-A74 Other diseases caused by chlamydiae
0.644 0.356 0.000
A65-A69 Other spirochaetal diseases
0.644 0.356 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.644 0.356 0.000
A20-A28 Certain zoonotic bacterial diseases
0.644 0.356 0.000
A15-A19 Tuberculosis
0.644 0.356 0.000
J45.8 Mixed asthma
0.642 0.358 0.000
J45.1 Nonallergic asthma
0.642 0.358 0.000
S64 Injury of nerves at wrist and hand level
0.642 0.358 0.000
B25-B34 Other viral diseases
0.641 0.359 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.641 0.359 0.000
K74 Fibrosis and cirrhosis of liver
0.638 0.362 0.000
S52.5 Fracture of lower end of radius
0.638 0.362 0.000
A08 Viral and other specified intestinal infections
0.637 0.363 0.000
Y95 Nosocomial condition
0.636 0.364 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.634 0.366 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.634 0.366 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.634 0.366 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.634 0.366 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.634 0.366 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.633 0.367 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.633 0.367 0.000
J18.0 Bronchopneumonia, unspecified
0.632 0.368 0.000
T93 Sequelae of injuries of lower limb
0.632 0.368 0.000
K52 Other non-infective gastro-enteritis and colitis
0.631 0.369 0.000
M20-M25 Other joint disorders
0.631 0.369 0.000
J39 Other diseases of upper respiratory tract
0.630 0.370 0.000
K65.0 Acute peritonitis
0.629 0.371 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.626 0.374 0.000
S72 Fracture of femur
0.626 0.374 0.000
G51 Facial nerve disorders
0.625 0.375 0.000
M81 Osteoporosis without pathological fracture
0.624 0.376 0.000
M05-M14 Inflammatory polyarthropathies
0.623 0.377 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.623 0.377 0.000
M70-M79 Other soft tissue disorders
0.622 0.378 0.000
S22.2 Fracture of sternum
0.622 0.378 0.000
D55-D59 Haemolytic anaemias
0.622 0.378 0.000
G70-G73 Diseases of myoneural junction and muscle
0.621 0.378 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.621 0.378 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.621 0.378 0.000
K13 Other diseases of lip and oral mucosa
0.621 0.379 0.000
J36 Peritonsillar abscess
0.621 0.379 0.000
D60-D64 Aplastic and other anaemias
0.621 0.379 0.000
J17 Pneumonia in diseases classified elsewhere
0.619 0.381 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.619 0.381 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.619 0.381 0.000
J12 Viral pneumonia, not elsewhere classified
0.619 0.381 0.000
J11 Influenza, virus not identified
0.619 0.381 0.000
J10 Influenza due to identified influenza virus
0.619 0.381 0.000
J14 Pneumonia due to Haemophilus influenzae
0.619 0.381 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.619 0.381 0.000
J09 Influenza due to certain identified influenza virus
0.619 0.381 0.000
A30-A49 Other bacterial diseases
0.619 0.381 0.000
A04 Other bacterial intestinal infections
0.617 0.383 0.000
D45 Polycythaemia vera
0.617 0.383 0.000
K50.1 Crohn's disease of large intestine
0.615 0.385 0.000
J43 Emphysema
0.614 0.386 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.613 0.386 0.000
C73 Malignant neoplasm of thyroid gland
0.612 0.388 0.000
S29 Other and unspecified injuries of thorax
0.610 0.390 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.610 0.390 0.000
S27 Injury of other and unspecified intrathoracic organs
0.610 0.390 0.000
S26 Injury of heart
0.610 0.390 0.000
S25 Injury of blood vessels of thorax
0.610 0.390 0.000
S24 Injury of nerves and spinal cord at thorax level
0.610 0.390 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.610 0.390 0.000
S21 Open wound of thorax
0.610 0.390 0.000
S20 Superficial injury of thorax
0.610 0.390 0.000
K50.9 Crohn's disease, unspecified
0.610 0.390 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.609 0.391 0.000
C16.0 Cardia
0.607 0.393 0.000
K12 Stomatitis and related lesions
0.607 0.393 0.000
S22.0 Fracture of thoracic vertebra
0.607 0.393 0.000
C16.9 Stomach, unspecified
0.605 0.395 0.000
S69 Other and unspecified injuries of wrist and hand
0.604 0.396 0.000
S68 Traumatic amputation of wrist and hand
0.604 0.396 0.000
S67 Crushing injury of wrist and hand
0.604 0.396 0.000
S65 Injury of blood vessels at wrist and hand level
0.604 0.396 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.604 0.396 0.000
S60 Superficial injury of wrist and hand
0.604 0.396 0.000
M86-M90 Other osteopathies
0.603 0.397 0.000
J37 Chronic laryngitis and laryngotracheitis
0.602 0.398 0.000
D50-D53 Nutritional anaemias
0.600 0.400 0.000
D73 Diseases of spleen
0.600 0.400 0.000
C77.8 Lymph nodes of multiple regions
0.600 0.400 0.000
C77.4 Inguinal and lower limb lymph nodes
0.600 0.400 0.000
K92.9 Disease of digestive system, unspecified
0.600 0.400 0.000
K92.8 Other specified diseases of digestive system
0.600 0.400 0.000
S22.40 Multiple fractures of ribs (closed)
0.600 0.400 0.000
K05 Gingivitis and periodontal diseases
0.599 0.401 0.000
Y40 Systemic antibiotics
0.599 0.401 0.000
K91.3 Postoperative intestinal obstruction
0.598 0.402 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.597 0.402 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.597 0.403 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.596 0.403 0.000
Chapter VII Diseases of the eye and adnexa
0.596 0.404 0.000
K02.9 Dental caries, unspecified
0.596 0.404 0.000
C25.9 Pancreas, unspecified
0.595 0.404 0.000
C15.8 Overlapping lesion of oesophagus
0.594 0.406 0.000
C15.4 Middle third of oesophagus
0.594 0.406 0.000
C15.3 Upper third of oesophagus
0.594 0.406 0.000
C15.2 Abdominal part of oesophagus
0.594 0.406 0.000
C15.1 Thoracic part of oesophagus
0.594 0.406 0.000
C15.0 Cervical part of oesophagus
0.594 0.406 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.593 0.407 0.000
H80-H83 Diseases of inner ear
0.592 0.408 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.591 0.409 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.591 0.409 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.590 0.409 0.000
Q80-Q89 Other congenital malformations
0.590 0.409 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.590 0.409 0.000
Q50-Q56 Congenital malformations of genital organs
0.590 0.409 0.000
Q35-Q37 Cleft lip and cleft palate
0.590 0.409 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.590 0.409 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.590 0.409 0.000
Q00-Q07 Congenital malformations of the nervous system
0.590 0.409 0.000
S59 Other and unspecified injuries of forearm
0.590 0.410 0.000
S58 Traumatic amputation of forearm
0.590 0.410 0.000
S57 Crushing injury of forearm
0.590 0.410 0.000
S56 Injury of muscle and tendon at forearm level
0.590 0.410 0.000
S55 Injury of blood vessels at forearm level
0.590 0.410 0.000
S54 Injury of nerves at forearm level
0.590 0.410 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.590 0.410 0.000
S51 Open wound of forearm
0.590 0.410 0.000
S50 Superficial injury of forearm
0.590 0.410 0.000
Y89 Sequelae of other external causes
0.589 0.411 0.000
Y88 Sequelae of surgical and medical care as external cause
0.589 0.411 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.589 0.411 0.000
Y85 Sequelae of transport accidents
0.589 0.411 0.000
C77.5 Intrapelvic lymph nodes
0.588 0.412 0.000
K10 Other diseases of jaws
0.587 0.413 0.000
K09 Cysts of oral region, not elsewhere classified
0.587 0.413 0.000
K07 Dentofacial anomalies [including malocclusion]
0.587 0.413 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.587 0.413 0.000
K03 Other diseases of hard tissues of teeth
0.587 0.413 0.000
K00 Disorders of tooth development and eruption
0.587 0.413 0.000
K04 Diseases of pulp and periapical tissues
0.585 0.414 0.000
B44 Aspergillosis
0.585 0.415 0.000
J38.3 Other diseases of vocal cords
0.584 0.415 0.000
Y59 Other and unspecified vaccines and biological substances
0.584 0.416 0.000
Y58 Bacterial vaccines
0.584 0.416 0.000
Y57 Other and unspecified drugs and medicaments
0.584 0.416 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.584 0.416 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.584 0.416 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.584 0.416 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.584 0.416 0.000
Y52 Agents primarily affecting the cardiovascular system
0.584 0.416 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.584 0.416 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.584 0.416 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.584 0.416 0.000
Y48 Anaesthetics and therapeutic gases
0.584 0.416 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.584 0.416 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.584 0.416 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.584 0.416 0.000
Y44 Agents primarily affecting blood constituents
0.584 0.416 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.584 0.416 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.583 0.417 0.000
K66 Other disorders of peritoneum
0.581 0.419 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.581 0.419 0.000
C79.6 Secondary malignant neoplasm of ovary
0.581 0.419 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.581 0.419 0.000
C79.2 Secondary malignant neoplasm of skin
0.581 0.419 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.581 0.419 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.581 0.419 0.000
Chapter XIV Diseases of the genitourinary system
0.577 0.423 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.577 0.423 0.000
M91-M94 Chondropathies
0.577 0.423 0.000
M60-M63 Disorders of muscles
0.577 0.423 0.000
M00-M03 Infectious arthropathies
0.577 0.423 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.575 0.425 0.000
S52.50 Fracture of lower end of radius (closed)
0.573 0.427 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.573 0.427 0.000
C18.2 Ascending colon
0.573 0.427 0.000
J00-J06 Acute upper respiratory infections
0.572 0.427 0.000
G90-G99 Other disorders of the nervous system
0.572 0.428 0.000
K14 Diseases of tongue
0.571 0.429 0.000
G40-G47 Episodic and paroxysmal disorders
0.571 0.429 0.000
K70.3 Alcoholic cirrhosis of liver
0.570 0.430 0.000
Y42.7 Androgens and anabolic congeners
0.570 0.430 0.000
M40-M43 Deforming dorsopathies
0.570 0.430 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.570 0.430 0.000
M20 Acquired deformities of fingers and toes
0.570 0.430 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.569 0.431 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.568 0.431 0.000
K77 Liver disorders in diseases classified elsewhere
0.568 0.432 0.000
K75 Other inflammatory liver diseases
0.568 0.432 0.000
K73 Chronic hepatitis, not elsewhere classified
0.568 0.432 0.000
K72 Hepatic failure, not elsewhere classified
0.568 0.432 0.000
K71 Toxic liver disease
0.568 0.432 0.000
J33.0 Polyp of nasal cavity
0.568 0.432 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.568 0.432 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.568 0.432 0.000
G58 Other mononeuropathies
0.568 0.432 0.000
G54 Nerve root and plexus disorders
0.568 0.432 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.568 0.432 0.000
G52 Disorders of other cranial nerves
0.568 0.432 0.000
G50 Disorders of trigeminal nerve
0.568 0.432 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.568 0.432 0.000
S62.6 Fracture of other finger
0.566 0.434 0.000
S00 Superficial injury of head
0.565 0.435 0.000
G57 Mononeuropathies of lower limb
0.564 0.435 0.000
C77.2 Intra-abdominal lymph nodes
0.563 0.437 0.000
M81.9 Osteoporosis, unspecified
0.563 0.437 0.000
C54 Malignant neoplasm of corpus uteri
0.563 0.437 0.000
J20-J22 Other acute lower respiratory infections
0.562 0.438 0.000
J90 Pleural effusion, not elsewhere classified
0.560 0.440 0.000
W25 Contact with sharp glass
0.559 0.441 0.000
S52.6 Fracture of lower end of both ulna and radius
0.559 0.441 0.000
A07 Other protozoal intestinal diseases
0.558 0.442 0.000
A06 Amoebiasis
0.558 0.442 0.000
A05 Other bacterial foodborne intoxications
0.558 0.442 0.000
A03 Shigellosis
0.558 0.442 0.000
A02 Other Salmonella infections
0.558 0.442 0.000
A01 Typhoid and paratyphoid fevers
0.558 0.442 0.000
A00 Cholera
0.558 0.442 0.000
C50.4 Upper-outer quadrant of breast
0.557 0.443 0.000
K60 Fissure and fistula of anal and rectal regions
0.557 0.443 0.000
M79.6 Pain in limb
0.556 0.444 0.000
S22.9 Fracture of bony thorax, part unspecified
0.555 0.444 0.000
S22.8 Fracture of other parts of bony thorax
0.555 0.444 0.000
S22.5 Flail chest
0.555 0.444 0.000
S22.3 Fracture of rib
0.555 0.444 0.000
S22.1 Multiple fractures of thoracic spine
0.555 0.444 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.555 0.445 0.000
J18.8 Other pneumonia, organism unspecified
0.554 0.446 0.000
J18.2 Hypostatic pneumonia, unspecified
0.554 0.446 0.000
K08 Other disorders of teeth and supporting structures
0.554 0.446 0.000
K92.0 Haematemesis
0.553 0.447 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.553 0.447 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.553 0.447 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.553 0.447 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.553 0.447 0.000
D46 Myelodysplastic syndromes
0.553 0.447 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.553 0.447 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.553 0.447 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.553 0.447 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.553 0.447 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.553 0.447 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.553 0.447 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.553 0.447 0.000
D22 Melanocytic naevi
0.553 0.447 0.000
K90.0 Coeliac disease
0.552 0.448 0.000
C77.1 Intrathoracic lymph nodes
0.551 0.448 0.000
T98 Sequelae of other and unspecified effects of external causes
0.550 0.450 0.000
T95 Sequelae of burns, corrosions and frostbite
0.550 0.450 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.550 0.450 0.000
T92 Sequelae of injuries of upper limb
0.550 0.450 0.000
T91 Sequelae of injuries of neck and trunk
0.550 0.450 0.000
T90 Sequelae of injuries of head
0.550 0.450 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.550 0.450 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.550 0.450 0.000
M80 Osteoporosis with pathological fracture
0.550 0.450 0.000
M13 Other arthritis
0.550 0.450 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.550 0.450 0.000
C74 Malignant neoplasm of adrenal gland
0.550 0.450 0.000
K55 Vascular disorders of intestine
0.550 0.450 0.000
C16.8 Overlapping lesion of stomach
0.549 0.451 0.000
C16.6 Greater curvature of stomach, unspecified
0.549 0.451 0.000
C16.5 Lesser curvature of stomach, unspecified
0.549 0.451 0.000
C16.4 Pylorus
0.549 0.451 0.000
C16.3 Pyloric antrum
0.549 0.451 0.000
C16.2 Body of stomach
0.549 0.451 0.000
C16.1 Fundus of stomach
0.549 0.451 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.548 0.452 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.548 0.452 0.000
Y98 Lifestyle-related condition
0.548 0.452 0.000
Y97 Environmental-pollution-related condition
0.548 0.452 0.000
Y96 Work-related condition
0.548 0.452 0.000
S79 Other and unspecified injuries of hip and thigh
0.548 0.452 0.000
S78 Traumatic amputation of hip and thigh
0.548 0.452 0.000
S77 Crushing injury of hip and thigh
0.548 0.452 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.548 0.452 0.000
S75 Injury of blood vessels at hip and thigh level
0.548 0.452 0.000
S74 Injury of nerves at hip and thigh level
0.548 0.452 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.548 0.452 0.000
S71 Open wound of hip and thigh
0.548 0.452 0.000
S70 Superficial injury of hip and thigh
0.548 0.452 0.000
H65-H75 Diseases of middle ear and mastoid
0.547 0.453 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.546 0.454 0.000
D75 Other diseases of blood and blood-forming organs
0.546 0.454 0.000
D74 Methaemoglobinaemia
0.546 0.454 0.000
D72 Other disorders of white blood cells
0.546 0.454 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.546 0.454 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.546 0.454 0.000
C53 Malignant neoplasm of cervix uteri
0.544 0.456 0.000
W19 Unspecified fall
0.544 0.456 0.000
M45-M49 Spondylopathies
0.543 0.457 0.000
K01 Embedded and impacted teeth
0.542 0.458 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.542 0.458 0.000
G56.8 Other mononeuropathies of upper limb
0.542 0.458 0.000
G56.4 Causalgia
0.542 0.458 0.000
G56.3 Lesion of radial nerve
0.542 0.458 0.000
G56.1 Other lesions of median nerve
0.542 0.458 0.000
M50-M54 Other dorsopathies
0.541 0.459 0.000
K35 Acute appendicitis
0.541 0.459 0.000
J35.1 Hypertrophy of tonsils
0.541 0.459 0.000
K11.8 Other diseases of salivary glands
0.540 0.459 0.000
C18.9 Colon, unspecified
0.540 0.460 0.000
J30 Vasomotor and allergic rhinitis
0.539 0.461 0.000
K50.0 Crohn's disease of small intestine
0.538 0.462 0.000
G20 Parkinson's disease
0.538 0.462 0.000
K65.9 Peritonitis, unspecified
0.538 0.462 0.000
S61.0 Open wound of finger(s) without damage to nail
0.538 0.462 0.000
Q61 Cystic kidney disease
0.538 0.462 0.000
J96 Respiratory failure, not elsewhere classified
0.536 0.463 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.536 0.463 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.536 0.464 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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