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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77700287
log Bayes Factor = 19.9573
Chromosome 4   position 174,978,888  (GRCh37) Explore rs77700287 on Ensembl!
Variant rs77700287 is part of Cluster X0177

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.996 0.004 0.000
Chapter XIV Diseases of the genitourinary system
0.995 0.005 0.000
Chapter I Certain infectious and parasitic diseases
0.995 0.005 0.000
S00-S09 Injuries to the head
0.995 0.005 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.993 0.007 0.000
I25 Chronic ischaemic heart disease
0.992 0.008 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.990 0.010 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.988 0.012 0.000
I60-I69 Cerebrovascular diseases
0.985 0.015 0.000
I25.1 Atherosclerotic heart disease
0.985 0.015 0.000
Chapter XX External causes of morbidity and mortality
0.983 0.017 0.000
R15 Faecal incontinence
0.982 0.018 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.980 0.020 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.980 0.020 0.000
M70-M79 Other soft tissue disorders
0.979 0.021 0.000
S00 Superficial injury of head
0.975 0.025 0.000
B95-B98 Bacterial, viral and other infectious agents
0.970 0.030 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.969 0.031 0.000
S60-S69 Injuries to the wrist and hand
0.967 0.033 0.000
E70-E90 Metabolic disorders
0.965 0.035 0.000
N30-N39 Other diseases of urinary system
0.962 0.038 0.000
N17-N19 Renal failure
0.960 0.040 0.000
O60-O75 Complications of labour and delivery
0.957 0.043 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.955 0.045 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.944 0.056 0.000
E86 Volume depletion
0.942 0.058 0.000
A30-A49 Other bacterial diseases
0.939 0.061 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.930 0.070 0.000
S01 Open wound of head
0.924 0.076 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.923 0.077 0.000
L82 Seborrhoeic keratosis
0.922 0.078 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.919 0.081 0.000
M20-M25 Other joint disorders
0.918 0.082 0.000
M50-M54 Other dorsopathies
0.917 0.083 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.917 0.083 0.000
E20-E35 Disorders of other endocrine glands
0.916 0.084 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.915 0.085 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.915 0.085 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.914 0.086 0.000
I24 Other acute ischaemic heart diseases
0.914 0.086 0.000
Chapter VI Diseases of the nervous system
0.910 0.090 0.000
N18 Chronic renal failure
0.903 0.097 0.000
E10-E14 Diabetes mellitus
0.901 0.099 0.000
I67 Other cerebrovascular diseases
0.897 0.103 0.000
A41 Other septicaemia
0.895 0.105 0.000
Chapter XI Diseases of the digestive system
0.894 0.106 0.000
R42 Dizziness and giddiness
0.893 0.107 0.000
R19.4 Change in bowel habit
0.891 0.109 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.890 0.110 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.887 0.113 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.887 0.113 0.000
M75 Shoulder lesions
0.885 0.115 0.000
S00.8 Superficial injury of other parts of head
0.884 0.116 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.883 0.117 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.882 0.118 0.000
N20-N23 Urolithiasis
0.874 0.126 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.874 0.126 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.870 0.130 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.870 0.130 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.869 0.131 0.000
T39.0 Salicylates
0.869 0.131 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.868 0.132 0.000
I65.2 Occlusion and stenosis of carotid artery
0.864 0.136 0.000
A00-A09 Intestinal infectious diseases
0.864 0.136 0.000
M79.6 Pain in limb
0.862 0.138 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.862 0.138 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.860 0.140 0.000
M05-M14 Inflammatory polyarthropathies
0.860 0.140 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.855 0.145 0.000
I20 Angina pectoris
0.855 0.145 0.000
M25 Other joint disorders, not elsewhere classified
0.854 0.146 0.000
R12 Heartburn
0.854 0.146 0.000
S20-S29 Injuries to the thorax
0.854 0.146 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.853 0.147 0.000
R16.1 Splenomegaly, not elsewhere classified
0.852 0.148 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.846 0.153 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.845 0.155 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.842 0.158 0.000
I30-I52 Other forms of heart disease
0.837 0.163 0.000
K55-K64 Other diseases of intestines
0.836 0.164 0.000
K62 Other diseases of anus and rectum
0.833 0.167 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.832 0.168 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.831 0.169 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.830 0.170 0.000
K62.1 Rectal polyp
0.830 0.170 0.000
R20 Disturbances of skin sensation
0.829 0.171 0.000
L89 Decubitus ulcer
0.828 0.172 0.000
L60-L75 Disorders of skin appendages
0.826 0.174 0.000
N19 Unspecified renal failure
0.823 0.177 0.000
M54 Dorsalgia
0.822 0.178 0.000
S61 Open wound of wrist and hand
0.821 0.179 0.000
S00.0 Superficial injury of scalp
0.819 0.181 0.000
M79.8 Other specified soft tissue disorders
0.818 0.182 0.000
E11 Non-insulin-dependent diabetes mellitus
0.818 0.182 0.000
Chapter V Mental and behavioural disorders
0.816 0.184 0.000
W20-W49 Exposure to inanimate mechanical forces
0.815 0.185 0.000
N39 Other disorders of urinary system
0.815 0.185 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.813 0.187 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.810 0.190 0.000
R14 Flatulence and related conditions
0.809 0.191 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.808 0.192 0.000
S00.1 Contusion of eyelid and periocular area
0.806 0.194 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.804 0.196 0.000
O72 Postpartum haemorrhage
0.804 0.196 0.000
I24.8 Other forms of acute ischaemic heart disease
0.802 0.198 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.801 0.199 0.000
S00.9 Superficial injury of head, part unspecified
0.801 0.199 0.000
M22 Disorders of patella
0.801 0.199 0.000
N30 Cystitis
0.800 0.200 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.800 0.200 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.798 0.202 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.794 0.206 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.791 0.209 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.790 0.210 0.000
M13 Other arthritis
0.788 0.212 0.000
S40-S49 Injuries to the shoulder and upper arm
0.785 0.215 0.000
I67.9 Cerebrovascular disease, unspecified
0.785 0.215 0.000
N10-N16 Renal tubulo-interstitial diseases
0.782 0.218 0.000
I61 Intracerebral haemorrhage
0.782 0.218 0.000
S02 Fracture of skull and facial bones
0.781 0.219 0.000
S00.3 Superficial injury of nose
0.781 0.219 0.000
X60-X84 Intentional self-harm
0.780 0.220 0.000
M50 Cervical disk disorders
0.780 0.220 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.779 0.221 0.000
I50 Heart failure
0.778 0.222 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.778 0.222 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.777 0.223 0.000
M79.7 Fibromyalgia
0.777 0.223 0.000
M75.2 Bicipital tendinitis
0.776 0.224 0.000
K90-K93 Other diseases of the digestive system
0.776 0.224 0.000
S69 Other and unspecified injuries of wrist and hand
0.775 0.225 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.775 0.225 0.000
S62 Fracture at wrist and hand level
0.775 0.225 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.774 0.226 0.000
N18.5 Chronic kidney disease, stage 5
0.773 0.227 0.000
E50-E64 Other nutritional deficiencies
0.773 0.227 0.000
S90-S99 Injuries to the ankle and foot
0.773 0.227 0.000
I25.5 Ischaemic cardiomyopathy
0.773 0.227 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.773 0.227 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.772 0.228 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.771 0.229 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.771 0.229 0.000
N00-N08 Glomerular diseases
0.771 0.229 0.000
K70-K77 Diseases of liver
0.771 0.229 0.000
O66 Other obstructed labour
0.769 0.231 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.768 0.232 0.000
L50-L54 Urticaria and erythema
0.768 0.232 0.000
M80-M85 Disorders of bone density and structure
0.767 0.233 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.766 0.234 0.000
K35-K38 Diseases of appendix
0.766 0.234 0.000
M65-M68 Disorders of synovium and tendon
0.766 0.234 0.000
N60-N64 Disorders of breast
0.766 0.234 0.000
N20 Calculus of kidney and ureter
0.765 0.235 0.000
R21 Rash and other nonspecific skin eruption
0.764 0.236 0.000
A41.9 Septicaemia, unspecified
0.762 0.238 0.000
R73 Elevated blood glucose level
0.762 0.238 0.000
W00-W19 Falls
0.762 0.238 0.000
A41.8 Other specified septicaemia
0.762 0.238 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.761 0.239 0.000
M54.9 Dorsalgia, unspecified
0.761 0.239 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.758 0.242 0.000
I42 Cardiomyopathy
0.757 0.243 0.000
S70-S79 Injuries to the hip and thigh
0.757 0.243 0.000
M00-M03 Infectious arthropathies
0.756 0.244 0.000
R13 Dysphagia
0.755 0.245 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.755 0.245 0.000
S50-S59 Injuries to the elbow and forearm
0.755 0.245 0.000
S09 Other and unspecified injuries of head
0.755 0.245 0.000
G56 Mononeuropathies of upper limb
0.754 0.246 0.000
N99-N99 Other disorders of the genitourinary system
0.753 0.247 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.752 0.248 0.000
R20.2 Paraesthesia of skin
0.752 0.248 0.000
N18.4 Chronic kidney disease, stage 4
0.751 0.249 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.748 0.252 0.000
M75.1 Rotator cuff syndrome
0.748 0.252 0.000
R45 Symptoms and signs involving emotional state
0.747 0.253 0.000
N34 Urethritis and urethral syndrome
0.747 0.253 0.000
I10-I15 Hypertensive diseases
0.746 0.253 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.746 0.254 0.000
E27 Other disorders of adrenal gland
0.746 0.254 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.745 0.255 0.000
I22 Subsequent myocardial infarction
0.744 0.255 0.000
N35 Urethral stricture
0.743 0.257 0.000
M75.0 Adhesive capsulitis of shoulder
0.743 0.257 0.000
I50.0 Congestive heart failure
0.743 0.257 0.000
E87.7 Fluid overload
0.742 0.258 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.742 0.258 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.742 0.258 0.000
Chapter VII Diseases of the eye and adnexa
0.742 0.258 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.741 0.259 0.000
I71 Aortic aneurysm and dissection
0.741 0.259 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.740 0.260 0.000
T43.2 Other and unspecified antidepressants
0.740 0.260 0.000
S01.5 Open wound of lip and oral cavity
0.739 0.260 0.000
S01.2 Open wound of nose
0.739 0.261 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.739 0.261 0.000
E21.0 Primary hyperparathyroidism
0.738 0.262 0.000
S01.9 Open wound of head, part unspecified
0.737 0.263 0.000
M13.9 Arthritis, unspecified
0.737 0.263 0.000
Chapter XXII Codes for special purposes
0.735 0.265 0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen
0.735 0.265 0.000
M79.60 Pain in limb (Multiple sites)
0.735 0.265 0.000
K57 Diverticular disease of intestine
0.735 0.265 0.000
R47-R49 Symptoms and signs involving speech and voice
0.735 0.265 0.000
Y52 Agents primarily affecting the cardiovascular system
0.734 0.266 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.734 0.266 0.000
I21 Acute myocardial infarction
0.733 0.266 0.000
E11.3 With ophthalmic complications
0.733 0.267 0.000
L40-L45 Papulosquamous disorders
0.732 0.268 0.000
M23 Internal derangement of knee
0.730 0.270 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.730 0.270 0.000
K83 Other diseases of biliary tract
0.729 0.270 0.000
K92 Other diseases of digestive system
0.729 0.271 0.000
K62.9 Disease of anus and rectum, unspecified
0.728 0.272 0.000
S01.8 Open wound of other parts of head
0.728 0.272 0.000
Y85 Sequelae of transport accidents
0.727 0.273 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.726 0.274 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.725 0.274 0.000
I49 Other cardiac arrhythmias
0.725 0.275 0.000
L81 Other disorders of pigmentation
0.725 0.275 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.724 0.276 0.000
L84 Corns and callosities
0.723 0.276 0.000
I69 Sequelae of cerebrovascular disease
0.723 0.277 0.000
G90-G99 Other disorders of the nervous system
0.723 0.277 0.000
M79.64 Pain in limb (Hand)
0.722 0.278 0.000
N17 Acute renal failure
0.722 0.278 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.721 0.279 0.000
R44.0 Auditory hallucinations
0.721 0.279 0.000
T66-T78 Other and unspecified effects of external causes
0.721 0.279 0.000
A08 Viral and other specified intestinal infections
0.720 0.280 0.000
S01.3 Open wound of ear
0.720 0.280 0.000
I62 Other nontraumatic intracranial haemorrhage
0.720 0.280 0.000
S01.1 Open wound of eyelid and periocular area
0.719 0.281 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.719 0.281 0.000
G56.2 Lesion of ulnar nerve
0.719 0.281 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.718 0.282 0.000
N32 Other disorders of bladder
0.717 0.282 0.000
L85 Other epidermal thickening
0.717 0.283 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
K62.8 Other specified diseases of anus and rectum
0.717 0.283 0.000
M77 Other enthesopathies
0.716 0.284 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
M91-M94 Chondropathies
0.715 0.285 0.000
M60-M63 Disorders of muscles
0.715 0.285 0.000
L90 Atrophic disorders of skin
0.715 0.285 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.714 0.286 0.000
B99-B99 Other infectious diseases
0.714 0.286 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.714 0.286 0.000
B65-B83 Helminthiases
0.714 0.286 0.000
B50-B64 Protozoal diseases
0.714 0.286 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.714 0.286 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.714 0.286 0.000
A80-A89 Viral infections of the central nervous system
0.714 0.286 0.000
A75-A79 Rickettsioses
0.714 0.286 0.000
A70-A74 Other diseases caused by chlamydiae
0.714 0.286 0.000
A65-A69 Other spirochaetal diseases
0.714 0.286 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.714 0.286 0.000
A20-A28 Certain zoonotic bacterial diseases
0.714 0.286 0.000
A15-A19 Tuberculosis
0.714 0.286 0.000
S08 Traumatic amputation of part of head
0.713 0.286 0.000
S07 Crushing injury of head
0.713 0.286 0.000
S05 Injury of eye and orbit
0.713 0.286 0.000
S04 Injury of cranial nerves
0.713 0.286 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.713 0.286 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.713 0.286 0.000
B15-B19 Viral hepatitis
0.713 0.287 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.713 0.287 0.000
R00 Abnormalities of heart beat
0.713 0.287 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.712 0.288 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.712 0.288 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.712 0.288 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.712 0.288 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.712 0.288 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.712 0.288 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.712 0.288 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.712 0.288 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.712 0.288 0.000
T36 Poisoning by systemic antibiotics
0.712 0.288 0.000
M54.3 Sciatica
0.712 0.288 0.000
I67.2 Cerebral atherosclerosis
0.711 0.289 0.000
I25.6 Silent myocardial ischaemia
0.711 0.289 0.000
I25.4 Coronary artery aneurysm
0.711 0.289 0.000
I25.3 Aneurysm of heart
0.711 0.289 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.711 0.289 0.000
N18.0 End-stage renal disease
0.710 0.290 0.000
L10-L14 Bullous disorders
0.710 0.290 0.000
E40-E46 Malnutrition
0.709 0.291 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.708 0.291 0.000
B25-B34 Other viral diseases
0.708 0.292 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.708 0.292 0.000
V10-V19 Pedal cyclist injured in transport accident
0.708 0.292 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.708 0.292 0.000
R44.1 Visual hallucinations
0.707 0.293 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.707 0.293 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.706 0.294 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.706 0.294 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.706 0.294 0.000
Y86 Sequelae of other accidents
0.706 0.294 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.706 0.294 0.000
I20.8 Other forms of angina pectoris
0.706 0.294 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.705 0.295 0.000
Y35-Y36 Legal intervention and operations of war
0.705 0.295 0.000
Y10-Y34 Event of undetermined intent
0.705 0.295 0.000
Y00-Y09 Assault
0.705 0.295 0.000
X85-X99 Assault
0.705 0.295 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.705 0.295 0.000
X50-X57 Overexertion, travel and privation
0.705 0.295 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.705 0.295 0.000
X30-X39 Exposure to forces of nature
0.705 0.295 0.000
X20-X29 Contact with venomous animals and plants
0.705 0.295 0.000
X10-X19 Contact with heat and hot substances
0.705 0.295 0.000
X00-X09 Exposure to smoke, fire and flames
0.705 0.295 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.705 0.295 0.000
W75-W84 Other accidental threats to breathing
0.705 0.295 0.000
W65-W74 Accidental drowning and submersion
0.705 0.295 0.000
W50-W64 Exposure to animate mechanical forces
0.705 0.295 0.000
V98-V99 Other and unspecified transport accidents
0.705 0.295 0.000
V95-V97 Air and space transport accidents
0.705 0.295 0.000
V90-V94 Water transport accidents
0.705 0.295 0.000
V80-V89 Other land transport accidents
0.705 0.295 0.000
V70-V79 Bus occupant injured in transport accident
0.705 0.295 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.705 0.295 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.705 0.295 0.000
V40-V49 Car occupant injured in transport accident
0.705 0.295 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.705 0.295 0.000
V20-V29 Motorcycle rider injured in transport accident
0.705 0.295 0.000
V01-V09 Pedestrian injured in transport accident
0.705 0.295 0.000
I67.8 Other specified cerebrovascular diseases
0.705 0.295 0.000
R16.0 Hepatomegaly, not elsewhere classified
0.705 0.295 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.703 0.297 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.703 0.297 0.000
L94 Other localised connective tissue disorders
0.703 0.297 0.000
L93 Lupus erythematosus
0.703 0.297 0.000
L87 Transepidermal elimination disorders
0.703 0.297 0.000
L88 Pyoderma gangrenosum
0.703 0.297 0.000
L86 Keratoderma in diseases classified elsewhere
0.703 0.297 0.000
L83 Acanthosis nigricans
0.703 0.297 0.000
L80 Vitiligo
0.703 0.297 0.000
O85-O92 Complications predominantly related to the puerperium
0.703 0.297 0.000
M76 Enthesopathies of lower limb, excluding foot
0.702 0.298 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.702 0.298 0.000
M71 Other bursopathies
0.702 0.298 0.000
R94 Abnormal results of function studies
0.702 0.298 0.000
I60 Subarachnoid haemorrhage
0.701 0.299 0.000
R79 Other abnormal findings of blood chemistry
0.701 0.299 0.000
E11.2 With renal complications
0.701 0.299 0.000
L60 Nail disorders
0.701 0.299 0.000
E88 Other metabolic disorders
0.700 0.300 0.000
N18.9 Chronic renal failure, unspecified
0.700 0.300 0.000
A49 Bacterial infection of unspecified site
0.700 0.300 0.000
S00.7 Multiple superficial injuries of head
0.699 0.301 0.000
S00.5 Superficial injury of lip and oral cavity
0.699 0.301 0.000
S00.4 Superficial injury of ear
0.699 0.301 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.699 0.301 0.000
M25.4 Effusion of joint
0.698 0.302 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.697 0.303 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.696 0.304 0.000
N39.4 Other specified urinary incontinence
0.695 0.305 0.000
E87.3 Alkalosis
0.695 0.305 0.000
R46 Symptoms and signs involving appearance and behaviour
0.694 0.305 0.000
R43 Disturbances of smell and taste
0.694 0.305 0.000
O48 Prolonged pregnancy
0.694 0.306 0.000
S67 Crushing injury of wrist and hand
0.694 0.306 0.000
S65 Injury of blood vessels at wrist and hand level
0.694 0.306 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.694 0.306 0.000
S60 Superficial injury of wrist and hand
0.694 0.306 0.000
L91 Hypertrophic disorders of skin
0.694 0.306 0.000
M34 Systemic sclerosis
0.693 0.307 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.693 0.307 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.692 0.308 0.000
Q60-Q64 Congenital malformations of the urinary system
0.692 0.308 0.000
E85 Amyloidosis
0.692 0.308 0.000
E84 Cystic fibrosis
0.692 0.308 0.000
E79 Disorders of purine and pyrimidine metabolism
0.692 0.308 0.000
E77 Disorders of glycoprotein metabolism
0.692 0.308 0.000
E76 Disorders of glycosaminoglycan metabolism
0.692 0.308 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.692 0.308 0.000
E74 Other disorders of carbohydrate metabolism
0.692 0.308 0.000
E73 Lactose intolerance
0.692 0.308 0.000
E72 Other disorders of amino-acid metabolism
0.692 0.308 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.692 0.308 0.000
E70 Disorders of aromatic amino-acid metabolism
0.692 0.308 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.692 0.308 0.000
E29 Testicular dysfunction
0.692 0.308 0.000
M22.4 Chondromalacia patellae
0.691 0.309 0.000
S64 Injury of nerves at wrist and hand level
0.690 0.310 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.690 0.310 0.000
N37 Urethral disorders in diseases classified elsewhere
0.690 0.310 0.000
N33 Bladder disorders in diseases classified elsewhere
0.690 0.310 0.000
I20.1 Angina pectoris with documented spasm
0.690 0.310 0.000
R07 Pain in throat and chest
0.690 0.310 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.690 0.310 0.000
M86-M90 Other osteopathies
0.689 0.311 0.000
M53 Other dorsopathies, not elsewhere classified
0.689 0.311 0.000
S06 Intracranial injury
0.689 0.311 0.000
N39.3 Stress incontinence
0.688 0.312 0.000
E13 Other specified diabetes mellitus
0.688 0.312 0.000
I73 Other peripheral vascular diseases
0.688 0.312 0.000
O74 Complications of anaesthesia during labour and delivery
0.686 0.313 0.000
O73 Retained placenta and membranes, without haemorrhage
0.686 0.313 0.000
O71 Other obstetric trauma
0.686 0.313 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.686 0.313 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.686 0.313 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.686 0.313 0.000
O62 Abnormalities of forces of labour
0.686 0.313 0.000
O61 Failed induction of labour
0.686 0.313 0.000
O60 Preterm delivery
0.686 0.313 0.000
Y40 Systemic antibiotics
0.686 0.314 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.685 0.315 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.685 0.315 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.685 0.315 0.000
T39.4 Antirheumatics, not elsewhere classified
0.685 0.315 0.000
T39.2 Pyrazolone derivatives
0.685 0.315 0.000
M21 Other acquired deformities of limbs
0.684 0.316 0.000
S68 Traumatic amputation of wrist and hand
0.683 0.316 0.000
I63 Cerebral infarction
0.683 0.317 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.683 0.317 0.000
M79.67 Pain in limb (Ankle and foot)
0.682 0.318 0.000
E10 Insulin-dependent diabetes mellitus
0.682 0.318 0.000
T39.1 4-Aminophenol derivatives
0.682 0.318 0.000
M40-M43 Deforming dorsopathies
0.682 0.318 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.681 0.319 0.000
M11 Other crystal arthropathies
0.680 0.320 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.680 0.320 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.679 0.321 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.679 0.321 0.000
N18.3 Chronic kidney disease, stage 3
0.678 0.322 0.000
R50-R69 General symptoms and signs
0.678 0.322 0.000
L89.1 Stage II decubitus ulcer
0.677 0.323 0.000
Q80-Q89 Other congenital malformations
0.677 0.323 0.000
M79.9 Soft tissue disorder, unspecified
0.677 0.323 0.000
M79.5 Residual foreign body in soft tissue
0.677 0.323 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.677 0.323 0.000
M79.3 Panniculitis, unspecified
0.677 0.323 0.000
M79.2 Neuralgia and neuritis, unspecified
0.677 0.323 0.000
M79.1 Myalgia
0.677 0.323 0.000
G82 Paraplegia and tetraplegia
0.676 0.324 0.000
G81 Hemiplegia
0.675 0.325 0.000
M25.5 Pain in joint
0.674 0.325 0.000
E22 Hyperfunction of pituitary gland
0.674 0.326 0.000
W20 Struck by thrown, projected or falling object
0.674 0.326 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.674 0.326 0.000
O63 Long labour
0.674 0.326 0.000
A48 Other bacterial diseases, not elsewhere classified
0.673 0.326 0.000
A44 Bartonellosis
0.673 0.326 0.000
A43 Nocardiosis
0.673 0.326 0.000
A42 Actinomycosis
0.673 0.326 0.000
A40 Streptococcal septicaemia
0.673 0.326 0.000
A39 Meningococcal infection
0.673 0.326 0.000
A37 Whooping cough
0.673 0.326 0.000
A36 Diphtheria
0.673 0.326 0.000
A32 Listeriosis
0.673 0.326 0.000
A31 Infection due to other mycobacteria
0.673 0.326 0.000
A30 Leprosy [Hansen's disease]
0.673 0.326 0.000
A46 Erysipelas
0.673 0.326 0.000
A38 Scarlet fever
0.673 0.326 0.000
A35 Other tetanus
0.673 0.326 0.000
A34 Obstetrical tetanus
0.673 0.326 0.000
A33 Tetanus neonatorum
0.673 0.326 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.673 0.327 0.000
N23 Unspecified renal colic
0.671 0.329 0.000
L03 Cellulitis
0.669 0.331 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.668 0.332 0.000
E87.0 Hyperosmolality and hypernatraemia
0.668 0.332 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.667 0.333 0.000
T43.9 Psychotropic drug, unspecified
0.667 0.333 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.667 0.333 0.000
T43.6 Psychostimulants with abuse potential
0.667 0.333 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.667 0.333 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.667 0.333 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.667 0.333 0.000
N36 Other disorders of urethra
0.667 0.333 0.000
E28 Ovarian dysfunction
0.667 0.333 0.000
M79.0 Rheumatism, unspecified
0.666 0.334 0.000
K83.1 Obstruction of bile duct
0.666 0.334 0.000
I74 Arterial embolism and thrombosis
0.666 0.334 0.000
I42.0 Dilated cardiomyopathy
0.665 0.335 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.665 0.335 0.000
K92.1 Melaena
0.665 0.335 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.665 0.335 0.000
K35 Acute appendicitis
0.664 0.335 0.000
M24 Other specific joint derangements
0.664 0.336 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.663 0.337 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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