TreeWAS – Variant ID: rs77885874

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter II Neoplasms	1.000	0.000
# Top node	0.999	0.001
C15-C26 Malignant neoplasms of digestive organs	0.997	0.003
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.993	0.007
Chapter VI Diseases of the nervous system	0.987	0.013
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.977	0.023
G40-G47 Episodic and paroxysmal disorders	0.972	0.028
C18 Malignant neoplasm of colon	0.969	0.031
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.965	0.035
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.952	0.048
C15 Malignant neoplasm of oesophagus	0.948	0.052
Chapter VII Diseases of the eye and adnexa	0.935	0.065
G40 Epilepsy	0.926	0.074
G43 Migraine	0.924	0.076
C78.0 Secondary malignant neoplasm of lung	0.917	0.083
Chapter XX External causes of morbidity and mortality	0.912	0.088
Chapter X Diseases of the respiratory system	0.908	0.092
Chapter XV Pregnancy, childbirth and the puerperium	0.896	0.104
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.887	0.113
D10-D36 Benign neoplasms	0.885	0.115
G40.9 Epilepsy, unspecified	0.883	0.117
G43.9 Migraine, unspecified	0.878	0.122
J09-J18 Influenza and pneumonia	0.871	0.129
C18.9 Colon, unspecified	0.866	0.134
G35-G37 Demyelinating diseases of the central nervous system	0.865	0.135
C18.2 Ascending colon	0.863	0.137
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.858	0.142
T36-T50 Poisoning by drugs, medicaments and biological substances	0.858	0.142
C15.9 Oesophagus, unspecified	0.857	0.143
C16 Malignant neoplasm of stomach	0.856	0.144
T15-T19 Effects of foreign body entering through natural orifice	0.854	0.146
C77.3 Axillary and upper limb lymph nodes	0.849	0.151
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.845	0.155
C15.5 Lower third of oesophagus	0.843	0.157
C18.0 Caecum	0.843	0.157
Chapter VIII Diseases of the ear and mastoid process	0.838	0.162
J18 Pneumonia, organism unspecified	0.833	0.167
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.831	0.169
D37-D48 Neoplasms of uncertain or unknown behaviour	0.819	0.181
D18 Haemangioma and lymphangioma, any site	0.815	0.185
C19 Malignant neoplasm of rectosigmoid junction	0.814	0.186
C78.2 Secondary malignant neoplasm of pleura	0.800	0.200
H01 Other inflammation of eyelid	0.793	0.207
C18.3 Hepatic flexure	0.788	0.212
J18.9 Pneumonia, unspecified	0.782	0.218
C43-C44 Melanoma and other malignant neoplasms of skin	0.781	0.219
C78.7 Secondary malignant neoplasm of liver	0.780	0.220
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.779	0.221
C77.8 Lymph nodes of multiple regions	0.778	0.222
C77.9 Lymph node, unspecified	0.778	0.222
G35 Multiple sclerosis	0.777	0.223
H55-H59 Other disorders of eye and adnexa	0.777	0.223
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.775	0.225
S60-S69 Injuries to the wrist and hand	0.773	0.226
T93 Sequelae of injuries of lower limb	0.773	0.227
C25 Malignant neoplasm of pancreas	0.770	0.230
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.768	0.232
H02 Other disorders of eyelid	0.766	0.233
J80-J84 Other respiratory diseases principally affecting the interstitium	0.766	0.234
S80-S89 Injuries to the knee and lower leg	0.765	0.235
D18.0 Haemangioma, any site	0.765	0.235
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.764	0.236
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.757	0.243
G45 Transient cerebral ischaemic attacks and related syndromes	0.756	0.244
S20-S29 Injuries to the thorax	0.756	0.244
J60-J70 Lung diseases due to external agents	0.752	0.248
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.749	0.251
G90-G99 Other disorders of the nervous system	0.748	0.252
S00-S09 Injuries to the head	0.746	0.254
H04 Disorders of lachrymal system	0.745	0.255
C77.2 Intra-abdominal lymph nodes	0.745	0.255
T18 Foreign body in alimentary tract	0.743	0.257
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.739	0.261
H46-H48 Disorders of optic nerve and visual pathways	0.735	0.265
Chapter XXII Codes for special purposes	0.734	0.265
S90-S99 Injuries to the ankle and foot	0.733	0.267
H10-H13 Disorders of conjunctiva	0.729	0.271
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.728	0.272
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.727	0.273
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.727	0.273
H01.0 Blepharitis	0.727	0.273
D00-D09 In situ neoplasms	0.725	0.275
C77.0 Lymph nodes of head, face and neck	0.724	0.276
G43.1 Migraine with aura [classical migraine]	0.724	0.276
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.723	0.276
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.722	0.278
O80-O84 Delivery	0.721	0.279
S40-S49 Injuries to the shoulder and upper arm	0.720	0.280
C50-C50 Malignant neoplasm of breast	0.718	0.282
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.717	0.283
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.716	0.284
C26 Malignant neoplasm of other and ill-defined digestive organs	0.715	0.285
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.715	0.285
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.715	0.285
C21 Malignant neoplasm of anus and anal canal	0.715	0.285
C17 Malignant neoplasm of small intestine	0.715	0.285
C23 Malignant neoplasm of gallbladder	0.715	0.285
C76 Malignant neoplasm of other and ill-defined sites	0.712	0.288
X60-X84 Intentional self-harm	0.712	0.288
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.712	0.288
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.711	0.289
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.710	0.290
H53-H54 Visual disturbances and blindness	0.710	0.290
C16.9 Stomach, unspecified	0.709	0.291
C51-C58 Malignant neoplasms of female genital organs	0.708	0.291
C18.4 Transverse colon	0.708	0.292
G70-G73 Diseases of myoneural junction and muscle	0.707	0.292
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.707	0.292
G00-G09 Inflammatory diseases of the central nervous system	0.707	0.292
H60-H62 Diseases of external ear	0.707	0.293
D70-D77 Other diseases of blood and blood-forming organs	0.707	0.293
J18.1 Lobar pneumonia, unspecified	0.704	0.296
D24 Benign neoplasm of breast	0.703	0.297
T79-T79 Certain early complications of trauma	0.700	0.300
T66-T78 Other and unspecified effects of external causes	0.700	0.300
T33-T35 Frostbite	0.700	0.300
T26-T28 Burns and corrosions confined to eye and internal organs	0.700	0.300
T20-T25 Burns and corrosions of external body surface, specified by site	0.700	0.300
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.700	0.300
T00-T07 Injuries involving multiple body regions	0.700	0.300
S10-S19 Injuries to the neck	0.700	0.300
Chapter IV Endocrine, nutritional and metabolic diseases	0.700	0.300
G30-G32 Other degenerative diseases of the nervous system	0.699	0.301
C79 Secondary malignant neoplasm of other sites	0.698	0.302
G46 Vascular syndromes of brain in cerebrovascular diseases	0.697	0.303
G41 Status epilepticus	0.697	0.303
C80 Malignant neoplasm without specification of site	0.697	0.303
O85-O92 Complications predominantly related to the puerperium	0.697	0.303
J13 Pneumonia due to Streptococcus pneumoniae	0.696	0.304
G80-G83 Cerebral palsy and other paralytic syndromes	0.696	0.304
C18.8 Overlapping lesion of colon	0.695	0.305
C18.6 Descending colon	0.695	0.305
C18.5 Splenic flexure	0.695	0.305
C18.1 Appendix	0.695	0.305
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.692	0.308
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.692	0.308
C78.4 Secondary malignant neoplasm of small intestine	0.692	0.308
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.692	0.308
C78.1 Secondary malignant neoplasm of mediastinum	0.692	0.308
G44 Other headache syndromes	0.692	0.308
C16.0 Cardia	0.690	0.309
M86-M90 Other osteopathies	0.690	0.310
Y43 Primarily systemic agents	0.690	0.310
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.690	0.310
J84 Other interstitial pulmonary diseases	0.684	0.316
C77.5 Intrapelvic lymph nodes	0.683	0.317
C77.4 Inguinal and lower limb lymph nodes	0.683	0.317
D36 Benign neoplasm of other and unspecified sites	0.681	0.319
C15.8 Overlapping lesion of oesophagus	0.680	0.320
C15.4 Middle third of oesophagus	0.680	0.320
C15.3 Upper third of oesophagus	0.680	0.320
C15.2 Abdominal part of oesophagus	0.680	0.320
C15.1 Thoracic part of oesophagus	0.680	0.320
C15.0 Cervical part of oesophagus	0.680	0.320
D27 Benign neoplasm of ovary	0.680	0.320
G20-G26 Extrapyramidal and movement disorders	0.679	0.320
D14 Benign neoplasm of middle ear and respiratory system	0.678	0.322
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.677	0.322
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.677	0.323
M05-M14 Inflammatory polyarthropathies	0.677	0.323
O00-O08 Pregnancy with abortive outcome	0.672	0.328
D11 Benign neoplasm of major salivary glands	0.671	0.329
M80-M85 Disorders of bone density and structure	0.671	0.329
C77.1 Intrathoracic lymph nodes	0.668	0.332
S50-S59 Injuries to the elbow and forearm	0.668	0.332
W20-W49 Exposure to inanimate mechanical forces	0.667	0.333
O60-O75 Complications of labour and delivery	0.666	0.334
H02.8 Other specified disorders of eyelid	0.665	0.335
G40.8 Other epilepsy	0.664	0.336
G40.7 Petit mal, unspecified, without grand mal seizures	0.664	0.336
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.664	0.336
G40.5 Special epileptic syndromes	0.664	0.336
G40.4 Other generalised epilepsy and epileptic syndromes	0.664	0.336
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.664	0.336
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.664	0.336
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.664	0.336
T18.1 Foreign body in oesophagus	0.663	0.337
G43.8 Other migraine	0.662	0.337
G43.3 Complicated migraine	0.662	0.337
G43.2 Status migrainosus	0.662	0.337
G43.0 Migraine without aura [common migraine]	0.662	0.337
T17 Foreign body in respiratory tract	0.662	0.338
C20 Malignant neoplasm of rectum	0.661	0.339
O94-O99 Other obstetric conditions, not elsewhere classified	0.661	0.339
W00-W19 Falls	0.660	0.340
D60-D64 Aplastic and other anaemias	0.659	0.341
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.658	0.342
S70-S79 Injuries to the hip and thigh	0.656	0.344
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.654	0.346
Y35-Y36 Legal intervention and operations of war	0.654	0.346
Y10-Y34 Event of undetermined intent	0.654	0.346
Y00-Y09 Assault	0.654	0.346
X85-X99 Assault	0.654	0.346
X58-X59 Accidental exposure to other and unspecified factors	0.654	0.346
X50-X57 Overexertion, travel and privation	0.654	0.346
X40-X49 Accidental poisoning by and exposure to noxious substances	0.654	0.346
X30-X39 Exposure to forces of nature	0.654	0.346
X20-X29 Contact with venomous animals and plants	0.654	0.346
X10-X19 Contact with heat and hot substances	0.654	0.346
X00-X09 Exposure to smoke, fire and flames	0.654	0.346
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.654	0.346
W75-W84 Other accidental threats to breathing	0.654	0.346
W65-W74 Accidental drowning and submersion	0.654	0.346
W50-W64 Exposure to animate mechanical forces	0.654	0.346
V98-V99 Other and unspecified transport accidents	0.654	0.346
V95-V97 Air and space transport accidents	0.654	0.346
V90-V94 Water transport accidents	0.654	0.346
V80-V89 Other land transport accidents	0.654	0.346
V70-V79 Bus occupant injured in transport accident	0.654	0.346
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.654	0.346
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.654	0.346
V40-V49 Car occupant injured in transport accident	0.654	0.346
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.654	0.346
V20-V29 Motorcycle rider injured in transport accident	0.654	0.346
V01-V09 Pedestrian injured in transport accident	0.654	0.346
D35 Benign neoplasm of other and unspecified endocrine glands	0.654	0.346
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.654	0.346
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.652	0.347
V10-V19 Pedal cyclist injured in transport accident	0.652	0.348
H43-H45 Disorders of vitreous body and globe	0.651	0.349
H65-H75 Diseases of middle ear and mastoid	0.650	0.350
D12.4 Descending colon	0.649	0.351
H04.2 Epiphora	0.648	0.352
M45-M49 Spondylopathies	0.648	0.352
T93.2 Sequelae of other fractures of lower limb	0.645	0.355
Y86 Sequelae of other accidents	0.642	0.358
H57 Other disorders of eye and adnexa	0.640	0.360
J69 Pneumonitis due to solids and liquids	0.640	0.360
J95-J99 Other diseases of the respiratory system	0.639	0.361
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.638	0.362
H40-H42 Glaucoma	0.636	0.364
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.636	0.364
H05 Disorders of orbit	0.636	0.364
H03 Disorders of eyelid in diseases classified elsewhere	0.636	0.364
D12.6 Colon, unspecified	0.636	0.364
H02.6 Xanthelasma of eyelid	0.635	0.364
D32 Benign neoplasm of meninges	0.635	0.365
D31 Benign neoplasm of eye and adnexa	0.635	0.365
D30 Benign neoplasm of urinary organs	0.635	0.365
D29 Benign neoplasm of male genital organs	0.635	0.365
D28 Benign neoplasm of other and unspecified female genital organs	0.635	0.365
D26 Other benign neoplasms of uterus	0.635	0.365
D21 Other benign neoplasms of connective and other soft tissue	0.635	0.365
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.635	0.365
D19 Benign neoplasm of mesothelial tissue	0.635	0.365
D16 Benign neoplasm of bone and articular cartilage	0.635	0.365
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.635	0.365
D10 Benign neoplasm of mouth and pharynx	0.635	0.365
D34 Benign neoplasm of thyroid gland	0.635	0.365
M40-M43 Deforming dorsopathies	0.634	0.366
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.634	0.366
D80-D89 Certain disorders involving the immune mechanism	0.633	0.366
M15-M19 Arthrosis	0.633	0.367
H80-H83 Diseases of inner ear	0.631	0.369
D33 Benign neoplasm of brain and other parts of central nervous system	0.630	0.370
D46 Myelodysplastic syndromes	0.630	0.370
Y43.3 Other antineoplastic drugs	0.629	0.371
Y60-Y69 Misadventures to patients during surgical and medical care	0.629	0.371
J30-J39 Other diseases of upper respiratory tract	0.628	0.372
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.628	0.372
S66 Injury of muscle and tendon at wrist and hand level	0.627	0.373
D12.3 Transverse colon	0.627	0.373
T93.8 Sequelae of other specified injuries of lower limb	0.626	0.373
H02.3 Blepharochalasis	0.626	0.374
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.626	0.374
H54 Blindness and low vision	0.624	0.376
J17 Pneumonia in diseases classified elsewhere	0.624	0.376
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.624	0.376
J15 Bacterial pneumonia, not elsewhere classified	0.624	0.376
J12 Viral pneumonia, not elsewhere classified	0.624	0.376
J11 Influenza, virus not identified	0.624	0.376
J10 Influenza due to identified influenza virus	0.624	0.376
J14 Pneumonia due to Haemophilus influenzae	0.624	0.376
J09 Influenza due to certain identified influenza virus	0.624	0.376
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.623	0.377
D17 Benign lipomatous neoplasm	0.621	0.379
C25.0 Head of pancreas	0.621	0.379
G37 Other demyelinating diseases of central nervous system	0.620	0.380
G36 Other acute disseminated demyelination	0.620	0.380
M20-M25 Other joint disorders	0.618	0.382
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.616	0.384
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.615	0.385
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.615	0.385
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.615	0.385
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.615	0.385
T46 Poisoning by agents primarily affecting the cardiovascular system	0.615	0.385
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.615	0.385
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.615	0.385
T41 Poisoning by anaesthetics and therapeutic gases	0.615	0.385
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.615	0.385
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.615	0.385
T36 Poisoning by systemic antibiotics	0.615	0.385
T98 Sequelae of other and unspecified effects of external causes	0.615	0.385
T95 Sequelae of burns, corrosions and frostbite	0.615	0.385
T94 Sequelae of injuries involving multiple and unspecified body regions	0.615	0.385
T92 Sequelae of injuries of upper limb	0.615	0.385
T91 Sequelae of injuries of neck and trunk	0.615	0.385
T90 Sequelae of injuries of head	0.615	0.385
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.615	0.385
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.615	0.385
S30 Superficial injury of abdomen, lower back and pelvis	0.615	0.385
S81 Open wound of lower leg	0.615	0.385
J90-J94 Other diseases of pleura	0.614	0.386
C16.8 Overlapping lesion of stomach	0.614	0.386
C16.6 Greater curvature of stomach, unspecified	0.614	0.386
C16.5 Lesser curvature of stomach, unspecified	0.614	0.386
C16.4 Pylorus	0.614	0.386
C16.3 Pyloric antrum	0.614	0.386
C16.2 Body of stomach	0.614	0.386
C16.1 Fundus of stomach	0.614	0.386
J00-J06 Acute upper respiratory infections	0.614	0.386
T19 Foreign body in genito-urinary tract	0.612	0.388
T15 Foreign body on external eye	0.612	0.388
T16 Foreign body in ear	0.612	0.388
D45 Polycythaemia vera	0.611	0.389
O20-O29 Other maternal disorders predominantly related to pregnancy	0.610	0.390
G61 Inflammatory polyneuropathy	0.609	0.391
S80 Superficial injury of lower leg	0.609	0.391
O16 Unspecified maternal hypertension	0.608	0.392
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.607	0.393
D70 Agranulocytosis	0.607	0.393
M91-M94 Chondropathies	0.606	0.394
M60-M63 Disorders of muscles	0.606	0.394
M00-M03 Infectious arthropathies	0.606	0.394
G45.9 Transient cerebral ischaemic attack, unspecified	0.601	0.399
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.600	0.400
O80 Single spontaneous delivery	0.599	0.401
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.597	0.403
C44 Other malignant neoplasms of skin	0.597	0.403
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.597	0.403
J18.8 Other pneumonia, organism unspecified	0.597	0.403
J18.2 Hypostatic pneumonia, unspecified	0.597	0.403
J18.0 Bronchopneumonia, unspecified	0.597	0.403
M65-M68 Disorders of synovium and tendon	0.596	0.403
D55-D59 Haemolytic anaemias	0.596	0.404
S05 Injury of eye and orbit	0.595	0.404
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.595	0.405
C43 Malignant melanoma of skin	0.593	0.407
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.592	0.408
H46 Optic neuritis	0.592	0.408
J84.9 Interstitial pulmonary disease, unspecified	0.590	0.410
S32 Fracture of lumbar spine and pelvis	0.590	0.410
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.587	0.413
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.587	0.413
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.587	0.413
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.587	0.413
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.587	0.413
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.587	0.413
H60 Otitis externa	0.587	0.413
Y95 Nosocomial condition	0.586	0.414
M07 Psoriatic and enteropathic arthropathies	0.585	0.415
D18.1 Lymphangioma, any site	0.584	0.416
S68 Traumatic amputation of wrist and hand	0.584	0.416
S09 Other and unspecified injuries of head	0.583	0.417
S20 Superficial injury of thorax	0.582	0.417
H11 Other disorders of conjunctiva	0.581	0.418
H04.1 Other disorders of lachrymal gland	0.580	0.420
M89 Other disorders of bone	0.580	0.420
E00-E07 Disorders of thyroid gland	0.578	0.421
E70-E90 Metabolic disorders	0.578	0.422
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.578	0.422
C64-C68 Malignant neoplasms of urinary tract	0.576	0.424
H16 Keratitis	0.575	0.425
H02.4 Ptosis of eyelid	0.573	0.427
Chapter I Certain infectious and parasitic diseases	0.570	0.430
H01.9 Inflammation of eyelid, unspecified	0.569	0.431
H01.8 Other specified inflammation of eyelid	0.569	0.431
H01.1 Non-infectious dermatoses of eyelid	0.569	0.431
H02.5 Other disorders affecting eyelid function	0.569	0.431
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.568	0.431
J84.1 Other interstitial pulmonary diseases with fibrosis	0.563	0.437
H54.0 Blindness, both eyes	0.563	0.437
G91 Hydrocephalus	0.561	0.439
M16 Coxarthrosis [arthrosis of hip]	0.561	0.439
D22 Melanocytic naevi	0.561	0.439
J69.0 Pneumonitis due to food and vomit	0.559	0.441
S91 Open wound of ankle and foot	0.559	0.441
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.559	0.441
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.559	0.441
S37 Injury of urinary and pelvic organs	0.559	0.441
S36 Injury of intra-abdominal organs	0.559	0.441
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.559	0.441
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.559	0.441
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.559	0.441
S31 Open wound of abdomen, lower back and pelvis	0.559	0.441
S42 Fracture of shoulder and upper arm	0.558	0.441
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.558	0.442
S64 Injury of nerves at wrist and hand level	0.558	0.442
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.557	0.443
H55 Nystagmus and other irregular eye movements	0.557	0.443
Q60-Q64 Congenital malformations of the urinary system	0.556	0.443
Y59 Other and unspecified vaccines and biological substances	0.556	0.444
Y58 Bacterial vaccines	0.556	0.444
Y57 Other and unspecified drugs and medicaments	0.556	0.444
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.556	0.444
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.556	0.444
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.556	0.444
Y53 Agents primarily affecting the gastro-intestinal system	0.556	0.444
Y52 Agents primarily affecting the cardiovascular system	0.556	0.444
Y51 Drugs primarily affecting the autonomic nervous system	0.556	0.444
Y50 Central nervous system stimulants, not elsewhere classified	0.556	0.444
Y49 Psychotropic drugs, not elsewhere classified	0.556	0.444
Y48 Anaesthetics and therapeutic gases	0.556	0.444
Y47 Sedatives, hypnotics and antianxiety drugs	0.556	0.444
Y46 Antiepileptics and anti-Parkinsonism drugs	0.556	0.444
Y44 Agents primarily affecting blood constituents	0.556	0.444
Y41 Other systemic anti-infectives and antiparasitics	0.556	0.444
Y40 Systemic antibiotics	0.556	0.444
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.555	0.445
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.555	0.445
S69 Other and unspecified injuries of wrist and hand	0.555	0.445
S67 Crushing injury of wrist and hand	0.555	0.445
S65 Injury of blood vessels at wrist and hand level	0.555	0.445
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.555	0.445
S60 Superficial injury of wrist and hand	0.555	0.445
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.554	0.445
T93.9 Sequelae of unspecified injury of lower limb	0.554	0.446
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.554	0.446
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.554	0.446
T93.4 Sequelae of injury of nerve of lower limb	0.554	0.446
T93.1 Sequelae of fracture of femur	0.554	0.446
T93.0 Sequelae of open wound of lower limb	0.554	0.446
O90 Complications of the puerperium, not elsewhere classified	0.553	0.446
D07 Carcinoma in situ of other and unspecified genital organs	0.553	0.447
C60-C63 Malignant neoplasms of male genital organs	0.552	0.447
C25.8 Overlapping lesion of pancreas	0.552	0.448
C25.7 Other parts of pancreas	0.552	0.448
C25.4 Endocrine pancreas	0.552	0.448
C25.3 Pancreatic duct	0.552	0.448
C25.2 Tail of pancreas	0.552	0.448
C25.1 Body of pancreas	0.552	0.448
S22 Fracture of rib(s), sternum and thoracic spine	0.552	0.448
H61 Other disorders of external ear	0.552	0.448
O15 Eclampsia	0.551	0.449
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.551	0.449
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.551	0.449
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.551	0.449
H02.7 Other degenerative disorders of eyelid and periocular area	0.550	0.450
H02.2 Lagophthalmos	0.550	0.450
J82 Pulmonary eosinophilia, not elsewhere classified	0.549	0.450
J80 Adult respiratory distress syndrome	0.549	0.450
S27 Injury of other and unspecified intrathoracic organs	0.549	0.450
C92 Myeloid leukaemia	0.549	0.451
D50-D53 Nutritional anaemias	0.549	0.451
S89 Other and unspecified injuries of lower leg	0.549	0.451
S88 Traumatic amputation of lower leg	0.549	0.451
S87 Crushing injury of lower leg	0.549	0.451
S86 Injury of muscle and tendon at lower leg level	0.549	0.451
S85 Injury of blood vessels at lower leg level	0.549	0.451
S84 Injury of nerves at lower leg level	0.549	0.451
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.548	0.452
C95 Leukaemia of unspecified cell type	0.548	0.452
C94 Other leukaemias of specified cell type	0.548	0.452
C93 Monocytic leukaemia	0.548	0.452
C88 Malignant immunoproliferative diseases	0.548	0.452
C86 Other specified types of T/NK-cell lymphoma	0.548	0.452
C84 Peripheral and cutaneous T-cell lymphomas	0.548	0.452
C81 Hodgkin's disease	0.548	0.452
H18 Other disorders of cornea	0.548	0.452
M47 Spondylosis	0.548	0.452
G99 Other disorders of nervous system in diseases classified elsewhere	0.547	0.452
J20-J22 Other acute lower respiratory infections	0.546	0.453
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.545	0.455
D06 Carcinoma in situ of cervix uteri	0.544	0.456
H20 Iridocyclitis	0.543	0.457
C90 Multiple myeloma and malignant plasma cell neoplasms	0.543	0.457
S62 Fracture at wrist and hand level	0.543	0.457
G63 Polyneuropathy in diseases classified elsewhere	0.543	0.457
G60 Hereditary and idiopathic neuropathy	0.543	0.457
G64 Other disorders of peripheral nervous system	0.543	0.457
G93 Other disorders of brain	0.542	0.458
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.542	0.458
G45.4 Transient global amnesia	0.542	0.458
G45.3 Amaurosis fugax	0.542	0.458
G45.2 Multiple and bilateral precerebral artery syndromes	0.542	0.458
G45.1 Carotid artery syndrome (hemispheric)	0.542	0.458
G45.0 Vertebro-basilar artery syndrome	0.542	0.458
S06 Intracranial injury	0.542	0.458
S29 Other and unspecified injuries of thorax	0.542	0.458
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.542	0.458
S26 Injury of heart	0.542	0.458
S25 Injury of blood vessels of thorax	0.542	0.458
S24 Injury of nerves and spinal cord at thorax level	0.542	0.458
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.542	0.458
S21 Open wound of thorax	0.542	0.458
C44.3 Skin of other and unspecified parts of face	0.542	0.458
H57.9 Disorder of eye and adnexa, unspecified	0.542	0.458
H00 Hordeolum and chalazion	0.539	0.461
W07 Fall involving chair	0.539	0.461
J70 Respiratory conditions due to other external agents	0.539	0.461
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.539	0.461
J67 Hypersensitivity pneumonitis due to organic dust	0.539	0.461
J66 Airway disease due to specific organic dust	0.539	0.461
J63 Pneumoconiosis due to other inorganic dusts	0.539	0.461
J62 Pneumoconiosis due to dust containing silica	0.539	0.461
J65 Pneumoconiosis associated with tuberculosis	0.539	0.461

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations