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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78222176
log Bayes Factor = 16.052
Chromosome 14   position 100,115,473  (GRCh37) Explore rs78222176 on Ensembl!
Variant rs78222176 is part of Cluster X0249

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
0.998 0.002 0.000
I60-I69 Cerebrovascular diseases
0.996 0.004 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.996 0.004 0.000
Chapter IX Diseases of the circulatory system
0.995 0.005 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.995 0.005 0.000
Chapter VI Diseases of the nervous system
0.994 0.006 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.994 0.006 0.000
A30-A49 Other bacterial diseases
0.993 0.007 0.000
C15-C26 Malignant neoplasms of digestive organs
0.992 0.008 0.000
C77.2 Intra-abdominal lymph nodes
0.990 0.010 0.000
S00-S09 Injuries to the head
0.982 0.018 0.000
C78.7 Secondary malignant neoplasm of liver
0.982 0.018 0.000
I63 Cerebral infarction
0.981 0.019 0.000
A41 Other septicaemia
0.981 0.019 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.977 0.023 0.000
I69 Sequelae of cerebrovascular disease
0.975 0.025 0.000
A41.9 Septicaemia, unspecified
0.973 0.027 0.000
C79 Secondary malignant neoplasm of other sites
0.962 0.038 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.961 0.039 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.960 0.040 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.958 0.042 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.953 0.047 0.000
Chapter X Diseases of the respiratory system
0.948 0.052 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.948 0.052 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.941 0.059 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.939 0.061 0.000
G90-G99 Other disorders of the nervous system
0.938 0.062 0.000
C18 Malignant neoplasm of colon
0.933 0.067 0.000
S50-S59 Injuries to the elbow and forearm
0.931 0.069 0.000
S09 Other and unspecified injuries of head
0.930 0.070 0.000
D70 Agranulocytosis
0.929 0.071 0.000
Chapter XX External causes of morbidity and mortality
0.927 0.073 0.000
C78.0 Secondary malignant neoplasm of lung
0.925 0.075 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.917 0.083 0.000
I63.9 Cerebral infarction, unspecified
0.912 0.088 0.000
C20 Malignant neoplasm of rectum
0.902 0.098 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.900 0.100 0.000
M45-M49 Spondylopathies
0.897 0.103 0.000
B35-B49 Mycoses
0.896 0.104 0.000
S00 Superficial injury of head
0.892 0.108 0.000
S52 Fracture of forearm
0.887 0.113 0.000
A46 Erysipelas
0.886 0.114 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.886 0.114 0.000
T81 Complications of procedures, not elsewhere classified
0.883 0.117 0.000
Chapter V Mental and behavioural disorders
0.881 0.119 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.879 0.121 0.000
Chapter VIII Diseases of the ear and mastoid process
0.878 0.122 0.000
C77.5 Intrapelvic lymph nodes
0.877 0.123 0.000
J95-J99 Other diseases of the respiratory system
0.876 0.124 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.874 0.126 0.000
T86 Failure and rejection of transplanted organs and tissues
0.873 0.127 0.000
C80 Malignant neoplasm without specification of site
0.872 0.128 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.867 0.133 0.000
S09.9 Unspecified injury of head
0.865 0.135 0.000
Chapter XXII Codes for special purposes
0.865 0.135 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.862 0.138 0.000
G58 Other mononeuropathies
0.861 0.139 0.000
I67 Other cerebrovascular diseases
0.857 0.143 0.000
C64-C68 Malignant neoplasms of urinary tract
0.857 0.143 0.000
T92 Sequelae of injuries of upper limb
0.857 0.143 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.856 0.144 0.000
M47 Spondylosis
0.854 0.146 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.854 0.146 0.000
S60-S69 Injuries to the wrist and hand
0.853 0.147 0.000
C25 Malignant neoplasm of pancreas
0.853 0.147 0.000
T90 Sequelae of injuries of head
0.850 0.150 0.000
B99-B99 Other infectious diseases
0.850 0.150 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.848 0.152 0.000
J00-J06 Acute upper respiratory infections
0.846 0.154 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.844 0.156 0.000
C77.9 Lymph node, unspecified
0.844 0.156 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.841 0.159 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.837 0.163 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.836 0.164 0.000
Chapter VII Diseases of the eye and adnexa
0.835 0.165 0.000
I60 Subarachnoid haemorrhage
0.833 0.167 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.831 0.169 0.000
J98 Other respiratory disorders
0.831 0.169 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.830 0.170 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.829 0.171 0.000
G91 Hydrocephalus
0.828 0.172 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.828 0.172 0.000
G95 Other diseases of spinal cord
0.826 0.174 0.000
S90-S99 Injuries to the ankle and foot
0.824 0.176 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.820 0.180 0.000
C18.7 Sigmoid colon
0.819 0.181 0.000
M80-M85 Disorders of bone density and structure
0.818 0.182 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.812 0.188 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.812 0.188 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.812 0.188 0.000
B37 Candidiasis
0.811 0.189 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.811 0.189 0.000
C79.2 Secondary malignant neoplasm of skin
0.811 0.189 0.000
J20-J22 Other acute lower respiratory infections
0.809 0.191 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.808 0.192 0.000
M50-M54 Other dorsopathies
0.808 0.192 0.000
I63.8 Other cerebral infarction
0.804 0.196 0.000
S40-S49 Injuries to the shoulder and upper arm
0.802 0.198 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.800 0.200 0.000
S52.1 Fracture of upper end of radius
0.798 0.201 0.000
D72 Other disorders of white blood cells
0.797 0.203 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.796 0.204 0.000
S52.0 Fracture of upper end of ulna
0.796 0.204 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.796 0.204 0.000
J30-J39 Other diseases of upper respiratory tract
0.795 0.205 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.795 0.205 0.000
H65-H75 Diseases of middle ear and mastoid
0.795 0.205 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.794 0.206 0.000
M47.8 Other spondylosis
0.794 0.206 0.000
S02 Fracture of skull and facial bones
0.792 0.208 0.000
S68 Traumatic amputation of wrist and hand
0.791 0.209 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.791 0.209 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.789 0.211 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.788 0.212 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.787 0.213 0.000
C18.9 Colon, unspecified
0.786 0.214 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.785 0.215 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.784 0.216 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.781 0.219 0.000
F30-F39 Mood [affective] disorders
0.780 0.220 0.000
I69.3 Sequelae of cerebral infarction
0.780 0.220 0.000
S10-S19 Injuries to the neck
0.779 0.221 0.000
D75 Other diseases of blood and blood-forming organs
0.778 0.222 0.000
G56 Mononeuropathies of upper limb
0.777 0.223 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.777 0.223 0.000
H80-H83 Diseases of inner ear
0.777 0.223 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.776 0.224 0.000
S09.8 Other specified injuries of head
0.776 0.224 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.775 0.225 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.774 0.226 0.000
C77.1 Intrathoracic lymph nodes
0.773 0.227 0.000
T93 Sequelae of injuries of lower limb
0.772 0.228 0.000
G58.9 Mononeuropathy, unspecified
0.772 0.228 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.769 0.231 0.000
T86.0 Bone-marrow transplant rejection
0.766 0.234 0.000
C25.9 Pancreas, unspecified
0.764 0.236 0.000
A00-A09 Intestinal infectious diseases
0.763 0.237 0.000
Y95 Nosocomial condition
0.763 0.237 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.761 0.239 0.000
T87 Complications peculiar to reattachment and amputation
0.760 0.240 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.759 0.241 0.000
J98.4 Other disorders of lung
0.759 0.241 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.759 0.241 0.000
I62 Other nontraumatic intracranial haemorrhage
0.756 0.244 0.000
I95 Hypotension
0.751 0.249 0.000
G54 Nerve root and plexus disorders
0.750 0.250 0.000
C18.0 Caecum
0.750 0.250 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.750 0.250 0.000
G91.9 Hydrocephalus, unspecified
0.749 0.251 0.000
H43-H45 Disorders of vitreous body and globe
0.749 0.251 0.000
A49 Bacterial infection of unspecified site
0.749 0.251 0.000
C85.1 B-cell lymphoma, unspecified
0.748 0.252 0.000
T81.9 Unspecified complication of procedure
0.747 0.253 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.747 0.253 0.000
S20-S29 Injuries to the thorax
0.747 0.253 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.746 0.254 0.000
T92.1 Sequelae of fracture of arm
0.746 0.254 0.000
B99 Other and unspecified infectious diseases
0.745 0.255 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.744 0.255 0.000
C18.3 Hepatic flexure
0.744 0.256 0.000
C44 Other malignant neoplasms of skin
0.744 0.256 0.000
M40-M43 Deforming dorsopathies
0.743 0.257 0.000
S00.3 Superficial injury of nose
0.740 0.260 0.000
M47.86 Other spondylosis (Lumbar region)
0.740 0.260 0.000
M46 Other inflammatory spondylopathies
0.740 0.260 0.000
J98.1 Pulmonary collapse
0.739 0.261 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.739 0.261 0.000
Chapter XIV Diseases of the genitourinary system
0.738 0.262 0.000
G81 Hemiplegia
0.737 0.263 0.000
S00.1 Contusion of eyelid and periocular area
0.735 0.265 0.000
S52.10 Fracture of upper end of radius (closed)
0.735 0.265 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.735 0.265 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.734 0.266 0.000
M91-M94 Chondropathies
0.734 0.266 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.732 0.268 0.000
V10-V19 Pedal cyclist injured in transport accident
0.732 0.268 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.731 0.269 0.000
G51 Facial nerve disorders
0.730 0.270 0.000
B02 Zoster [herpes zoster]
0.728 0.272 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.728 0.272 0.000
F32 Depressive episode
0.726 0.274 0.000
M47.2 Other spondylosis with radiculopathy
0.725 0.275 0.000
C91 Lymphoid leukaemia
0.725 0.275 0.000
F03 Unspecified dementia
0.723 0.277 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.722 0.277 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.722 0.278 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.721 0.279 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.721 0.279 0.000
H81 Disorders of vestibular function
0.721 0.279 0.000
G90 Disorders of autonomic nervous system
0.720 0.280 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.717 0.283 0.000
G56.2 Lesion of ulnar nerve
0.717 0.283 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B65-B83 Helminthiases
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.716 0.284 0.000
C18.1 Appendix
0.715 0.285 0.000
A80-A89 Viral infections of the central nervous system
0.715 0.285 0.000
H74 Other disorders of middle ear and mastoid
0.715 0.285 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.714 0.286 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.714 0.286 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.714 0.286 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.714 0.286 0.000
I00-I02 Acute rheumatic fever
0.713 0.286 0.000
J36 Peritonsillar abscess
0.713 0.287 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.713 0.287 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.713 0.287 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.713 0.287 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.713 0.287 0.000
D48.5 Skin
0.712 0.288 0.000
A48 Other bacterial diseases, not elsewhere classified
0.712 0.288 0.000
A44 Bartonellosis
0.712 0.288 0.000
A43 Nocardiosis
0.712 0.288 0.000
A42 Actinomycosis
0.712 0.288 0.000
A40 Streptococcal septicaemia
0.712 0.288 0.000
A39 Meningococcal infection
0.712 0.288 0.000
A37 Whooping cough
0.712 0.288 0.000
A36 Diphtheria
0.712 0.288 0.000
A32 Listeriosis
0.712 0.288 0.000
A31 Infection due to other mycobacteria
0.712 0.288 0.000
A30 Leprosy [Hansen's disease]
0.712 0.288 0.000
A38 Scarlet fever
0.712 0.288 0.000
A35 Other tetanus
0.712 0.288 0.000
A34 Obstetrical tetanus
0.712 0.288 0.000
A33 Tetanus neonatorum
0.712 0.288 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.712 0.288 0.000
C21 Malignant neoplasm of anus and anal canal
0.712 0.288 0.000
C17 Malignant neoplasm of small intestine
0.712 0.288 0.000
C23 Malignant neoplasm of gallbladder
0.712 0.288 0.000
T90.4 Sequelae of injury of eye and orbit
0.711 0.289 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.710 0.290 0.000
I05-I09 Chronic rheumatic heart diseases
0.710 0.290 0.000
J22 Unspecified acute lower respiratory infection
0.710 0.290 0.000
J35 Chronic diseases of tonsils and adenoids
0.709 0.291 0.000
W00-W19 Falls
0.709 0.291 0.000
T79-T79 Certain early complications of trauma
0.708 0.292 0.000
S52.00 Fracture of upper end of ulna (closed)
0.708 0.292 0.000
S52.4 Fracture of shafts of both ulna and radius
0.707 0.293 0.000
B15-B19 Viral hepatitis
0.707 0.293 0.000
M54 Dorsalgia
0.706 0.294 0.000
C80.9 Malignant neoplasm, unspecified
0.706 0.294 0.000
M84 Disorders of continuity of bone
0.706 0.294 0.000
S00.0 Superficial injury of scalp
0.706 0.294 0.000
S70-S79 Injuries to the hip and thigh
0.705 0.295 0.000
J09-J18 Influenza and pneumonia
0.705 0.295 0.000
S08 Traumatic amputation of part of head
0.704 0.296 0.000
S07 Crushing injury of head
0.704 0.296 0.000
S05 Injury of eye and orbit
0.704 0.296 0.000
S04 Injury of cranial nerves
0.704 0.296 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.704 0.296 0.000
C92 Myeloid leukaemia
0.704 0.296 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.703 0.297 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.703 0.297 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.703 0.297 0.000
A41.8 Other specified septicaemia
0.703 0.297 0.000
A41.4 Septicaemia due to anaerobes
0.703 0.297 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.703 0.297 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.703 0.297 0.000
M00-M03 Infectious arthropathies
0.703 0.297 0.000
G57 Mononeuropathies of lower limb
0.703 0.297 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.703 0.297 0.000
I67.2 Cerebral atherosclerosis
0.701 0.299 0.000
G52 Disorders of other cranial nerves
0.700 0.299 0.000
S80-S89 Injuries to the knee and lower leg
0.700 0.300 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.699 0.301 0.000
S01 Open wound of head
0.699 0.301 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.699 0.301 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.699 0.301 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.699 0.301 0.000
G95.2 Cord compression, unspecified
0.699 0.301 0.000
T17 Foreign body in respiratory tract
0.698 0.302 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.698 0.302 0.000
Q50-Q56 Congenital malformations of genital organs
0.696 0.303 0.000
M86-M90 Other osteopathies
0.696 0.304 0.000
H10-H13 Disorders of conjunctiva
0.696 0.304 0.000
S50 Superficial injury of forearm
0.696 0.304 0.000
G70-G73 Diseases of myoneural junction and muscle
0.695 0.305 0.000
N20-N23 Urolithiasis
0.695 0.305 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.695 0.305 0.000
H55-H59 Other disorders of eye and adnexa
0.695 0.305 0.000
G80 Infantile cerebral palsy
0.694 0.306 0.000
G53.0 Postzoster neuralgia
0.694 0.306 0.000
C51-C58 Malignant neoplasms of female genital organs
0.693 0.307 0.000
C79.6 Secondary malignant neoplasm of ovary
0.689 0.310 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.689 0.310 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.689 0.311 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.689 0.311 0.000
T82.3 Mechanical complication of other vascular grafts
0.689 0.311 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.689 0.311 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.689 0.311 0.000
T98 Sequelae of other and unspecified effects of external causes
0.688 0.312 0.000
T95 Sequelae of burns, corrosions and frostbite
0.688 0.312 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.688 0.312 0.000
T91 Sequelae of injuries of neck and trunk
0.688 0.312 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.688 0.312 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.688 0.312 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.688 0.312 0.000
G50 Disorders of trigeminal nerve
0.687 0.313 0.000
B37.8 Candidiasis of other sites
0.687 0.313 0.000
D55-D59 Haemolytic anaemias
0.687 0.313 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.686 0.314 0.000
C50-C50 Malignant neoplasm of breast
0.685 0.315 0.000
V20-V29 Motorcycle rider injured in transport accident
0.684 0.316 0.000
S06 Intracranial injury
0.684 0.316 0.000
M60-M63 Disorders of muscles
0.683 0.317 0.000
I67.8 Other specified cerebrovascular diseases
0.682 0.317 0.000
S00.7 Multiple superficial injuries of head
0.680 0.320 0.000
A04 Other bacterial intestinal infections
0.680 0.320 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.679 0.321 0.000
D74 Methaemoglobinaemia
0.679 0.321 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.679 0.321 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.679 0.321 0.000
B35 Dermatophytosis
0.679 0.321 0.000
H43 Disorders of vitreous body
0.677 0.323 0.000
T82.1 Mechanical complication of cardiac electronic device
0.676 0.323 0.000
I61 Intracerebral haemorrhage
0.675 0.325 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.675 0.325 0.000
C44.5 Skin of trunk
0.675 0.325 0.000
C16 Malignant neoplasm of stomach
0.675 0.325 0.000
C18.5 Splenic flexure
0.675 0.325 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.674 0.326 0.000
H81.0 Meniere's disease
0.674 0.326 0.000
B37.0 Candidal stomatitis
0.674 0.326 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.673 0.327 0.000
C95 Leukaemia of unspecified cell type
0.673 0.327 0.000
C94 Other leukaemias of specified cell type
0.673 0.327 0.000
C93 Monocytic leukaemia
0.673 0.327 0.000
C88 Malignant immunoproliferative diseases
0.673 0.327 0.000
C86 Other specified types of T/NK-cell lymphoma
0.673 0.327 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.673 0.327 0.000
F32.9 Depressive episode, unspecified
0.673 0.327 0.000
C22.0 Liver cell carcinoma
0.673 0.327 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.673 0.327 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.673 0.327 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.673 0.327 0.000
G92 Toxic encephalopathy
0.673 0.327 0.000
S52.6 Fracture of lower end of both ulna and radius
0.673 0.327 0.000
D48.7 Other specified sites
0.672 0.328 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.671 0.329 0.000
J03 Acute tonsillitis
0.670 0.330 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.669 0.330 0.000
S90 Superficial injury of ankle and foot
0.669 0.331 0.000
C18.8 Overlapping lesion of colon
0.669 0.331 0.000
S67 Crushing injury of wrist and hand
0.669 0.331 0.000
M15-M19 Arthrosis
0.668 0.332 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.668 0.332 0.000
S59 Other and unspecified injuries of forearm
0.667 0.333 0.000
S58 Traumatic amputation of forearm
0.667 0.333 0.000
S57 Crushing injury of forearm
0.667 0.333 0.000
S56 Injury of muscle and tendon at forearm level
0.667 0.333 0.000
S55 Injury of blood vessels at forearm level
0.667 0.333 0.000
S54 Injury of nerves at forearm level
0.667 0.333 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.667 0.333 0.000
D60-D64 Aplastic and other anaemias
0.667 0.333 0.000
S09.7 Multiple injuries of head
0.666 0.333 0.000
S09.2 Traumatic rupture of ear drum
0.666 0.333 0.000
S09.1 Injury of muscle and tendon of head
0.666 0.333 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.666 0.333 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.666 0.333 0.000
C78.2 Secondary malignant neoplasm of pleura
0.666 0.334 0.000
C77.8 Lymph nodes of multiple regions
0.666 0.334 0.000
C83.0 Small cell (diffuse)
0.665 0.335 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.664 0.336 0.000
Y35-Y36 Legal intervention and operations of war
0.664 0.336 0.000
Y10-Y34 Event of undetermined intent
0.664 0.336 0.000
Y00-Y09 Assault
0.664 0.336 0.000
X85-X99 Assault
0.664 0.336 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.664 0.336 0.000
X50-X57 Overexertion, travel and privation
0.664 0.336 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.664 0.336 0.000
X30-X39 Exposure to forces of nature
0.664 0.336 0.000
X20-X29 Contact with venomous animals and plants
0.664 0.336 0.000
X10-X19 Contact with heat and hot substances
0.664 0.336 0.000
X00-X09 Exposure to smoke, fire and flames
0.664 0.336 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.664 0.336 0.000
W75-W84 Other accidental threats to breathing
0.664 0.336 0.000
W65-W74 Accidental drowning and submersion
0.664 0.336 0.000
W50-W64 Exposure to animate mechanical forces
0.664 0.336 0.000
V98-V99 Other and unspecified transport accidents
0.664 0.336 0.000
V95-V97 Air and space transport accidents
0.664 0.336 0.000
V90-V94 Water transport accidents
0.664 0.336 0.000
V80-V89 Other land transport accidents
0.664 0.336 0.000
V70-V79 Bus occupant injured in transport accident
0.664 0.336 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.664 0.336 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.664 0.336 0.000
V40-V49 Car occupant injured in transport accident
0.664 0.336 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.664 0.336 0.000
V01-V09 Pedestrian injured in transport accident
0.664 0.336 0.000
M50 Cervical disk disorders
0.664 0.336 0.000
N30-N39 Other diseases of urinary system
0.664 0.336 0.000
C22.9 Liver, unspecified
0.663 0.337 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.663 0.337 0.000
D72.1 Eosinophilia
0.663 0.337 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.662 0.337 0.000
C22.1 Intrahepatic bile duct carcinoma
0.662 0.338 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.662 0.338 0.000
D48.1 Connective and other soft tissue
0.662 0.338 0.000
C15 Malignant neoplasm of oesophagus
0.661 0.339 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.661 0.339 0.000
U80 Agent resistant to penicillin and related antibiotics
0.661 0.339 0.000
F60-F69 Disorders of adult personality and behaviour
0.661 0.339 0.000
N35 Urethral stricture
0.660 0.340 0.000
C44.3 Skin of other and unspecified parts of face
0.659 0.341 0.000
H20 Iridocyclitis
0.659 0.341 0.000
N35.9 Urethral stricture, unspecified
0.659 0.341 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.657 0.343 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.655 0.345 0.000
D73 Diseases of spleen
0.655 0.345 0.000
H66 Suppurative and unspecified otitis media
0.655 0.345 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.654 0.345 0.000
G20-G26 Extrapyramidal and movement disorders
0.654 0.346 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.654 0.346 0.000
D46 Myelodysplastic syndromes
0.653 0.347 0.000
I60.8 Other subarachnoid haemorrhage
0.652 0.348 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.651 0.349 0.000
G81.9 Hemiplegia, unspecified
0.651 0.349 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.651 0.349 0.000
Y43 Primarily systemic agents
0.650 0.350 0.000
J06.9 Acute upper respiratory infection, unspecified
0.649 0.351 0.000
C77.4 Inguinal and lower limb lymph nodes
0.648 0.351 0.000
H43.3 Other vitreous opacities
0.648 0.352 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.648 0.352 0.000
J00 Acute nasopharyngitis [common cold]
0.648 0.352 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.647 0.353 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.647 0.353 0.000
G95.9 Disease of spinal cord, unspecified
0.647 0.353 0.000
M54.1 Radiculopathy
0.646 0.354 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.645 0.355 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.645 0.355 0.000
G30-G32 Other degenerative diseases of the nervous system
0.645 0.355 0.000
H73 Other disorders of tympanic membrane
0.645 0.355 0.000
S02.8 Fractures of other skull and facial bones
0.645 0.355 0.000
S42 Fracture of shoulder and upper arm
0.644 0.356 0.000
M49 Spondylopathies in diseases classified elsewhere
0.643 0.356 0.000
B44 Aspergillosis
0.643 0.357 0.000
B48 Other mycoses, not elsewhere classified
0.643 0.357 0.000
B47 Mycetoma
0.643 0.357 0.000
B46 Zygomycosis
0.643 0.357 0.000
B45 Cryptococcosis
0.643 0.357 0.000
B43 Chromomycosis and phaeomycotic abscess
0.643 0.357 0.000
B42 Sporotrichosis
0.643 0.357 0.000
B41 Paracoccidioidomycosis
0.643 0.357 0.000
B40 Blastomycosis
0.643 0.357 0.000
B39 Histoplasmosis
0.643 0.357 0.000
B38 Coccidioidomycosis
0.643 0.357 0.000
B36 Other superficial mycoses
0.643 0.357 0.000
B49 Unspecified mycosis
0.643 0.357 0.000
C81 Hodgkin's disease
0.642 0.357 0.000
D75.1 Secondary polycythaemia
0.642 0.358 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.642 0.358 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.641 0.359 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.641 0.359 0.000
I65.2 Occlusion and stenosis of carotid artery
0.640 0.360 0.000
S00.5 Superficial injury of lip and oral cavity
0.639 0.361 0.000
S00.4 Superficial injury of ear
0.639 0.361 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.639 0.361 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.639 0.361 0.000
J37 Chronic laryngitis and laryngotracheitis
0.639 0.361 0.000
D45 Polycythaemia vera
0.639 0.361 0.000
B37.3 Candidiasis of vulva and vagina
0.638 0.362 0.000
J60-J70 Lung diseases due to external agents
0.638 0.362 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.637 0.363 0.000
C44.7 Skin of lower limb, including hip
0.637 0.363 0.000
S52.9 Fracture of forearm, part unspecified
0.636 0.364 0.000
S52.8 Fracture of other parts of forearm
0.636 0.364 0.000
S52.7 Multiple fractures of forearm
0.636 0.364 0.000
S52.3 Fracture of shaft of radius
0.636 0.364 0.000
S52.2 Fracture of shaft of ulna
0.636 0.364 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.636 0.364 0.000
C18.2 Ascending colon
0.635 0.364 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.635 0.365 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.635 0.365 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.635 0.365 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.635 0.365 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.635 0.365 0.000
D80-D89 Certain disorders involving the immune mechanism
0.635 0.365 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.635 0.365 0.000
G58.8 Other specified mononeuropathies
0.635 0.365 0.000
I67.1 Cerebral aneurysm, nonruptured
0.634 0.366 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.634 0.366 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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