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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78253958
log Bayes Factor = 14.8213
Chromosome 2   position 51,204,750  (GRCh37) Explore rs78253958 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z95 Presence of cardiac and vascular implants and grafts
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
I25 Chronic ischaemic heart disease
0.995 0.005 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.994 0.006 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.990 0.010 0.000
I30-I52 Other forms of heart disease
0.984 0.016 0.000
Z92 Personal history of medical treatment
0.980 0.020 0.000
Z95.1 Presence of aortocoronary bypass graft
0.975 0.025 0.000
I20 Angina pectoris
0.974 0.026 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.973 0.027 0.000
C15-C26 Malignant neoplasms of digestive organs
0.971 0.029 0.000
Chapter V Mental and behavioural disorders
0.971 0.029 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.970 0.030 0.000
Chapter XX External causes of morbidity and mortality
0.970 0.030 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.969 0.031 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.966 0.034 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.964 0.036 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.961 0.039 0.000
Z86 Personal history of certain other diseases
0.957 0.043 0.000
E70-E90 Metabolic disorders
0.957 0.043 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.956 0.044 0.000
I45 Other conduction disorders
0.953 0.047 0.000
C18 Malignant neoplasm of colon
0.953 0.047 0.000
C79 Secondary malignant neoplasm of other sites
0.949 0.051 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.948 0.052 0.000
Z95.0 Presence of cardiac pacemaker
0.940 0.060 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.937 0.063 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.934 0.066 0.000
I45.1 Other and unspecified right bundle-branch block
0.932 0.068 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.931 0.069 0.000
I25.2 Old myocardial infarction
0.925 0.075 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.921 0.079 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.920 0.080 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.917 0.083 0.000
I25.1 Atherosclerotic heart disease
0.917 0.083 0.000
I44 Atrioventricular and left bundle-branch block
0.915 0.085 0.000
I20.0 Unstable angina
0.911 0.089 0.000
Chapter VIII Diseases of the ear and mastoid process
0.911 0.089 0.000
Z94 Transplanted organ and tissue status
0.910 0.090 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.910 0.090 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.907 0.093 0.000
E78.0 Pure hypercholesterolaemia
0.905 0.095 0.000
C18.9 Colon, unspecified
0.901 0.099 0.000
Z80 Family history of malignant neoplasm
0.901 0.099 0.000
M20-M25 Other joint disorders
0.900 0.100 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.899 0.101 0.000
Z48 Other surgical follow-up care
0.898 0.102 0.000
Z45 Adjustment and management of implanted device
0.898 0.102 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.895 0.105 0.000
I60-I69 Cerebrovascular diseases
0.895 0.105 0.000
M70-M79 Other soft tissue disorders
0.894 0.106 0.000
F10.0 Acute intoxication
0.894 0.106 0.000
I77 Other disorders of arteries and arterioles
0.893 0.107 0.000
Z86.7 Personal history of diseases of the circulatory system
0.892 0.108 0.000
E00-E07 Disorders of thyroid gland
0.889 0.111 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.886 0.114 0.000
I42 Cardiomyopathy
0.883 0.117 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.881 0.119 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.878 0.122 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.876 0.124 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.876 0.124 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.872 0.128 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.867 0.132 0.000
T39.1 4-Aminophenol derivatives
0.863 0.137 0.000
Z82.3 Family history of stroke
0.858 0.142 0.000
I73 Other peripheral vascular diseases
0.858 0.142 0.000
I05-I09 Chronic rheumatic heart diseases
0.858 0.142 0.000
S40-S49 Injuries to the shoulder and upper arm
0.856 0.144 0.000
Z46 Fitting and adjustment of other devices
0.854 0.146 0.000
H60-H62 Diseases of external ear
0.853 0.147 0.000
I22 Subsequent myocardial infarction
0.850 0.150 0.000
I77.1 Stricture of artery
0.841 0.159 0.000
M23 Internal derangement of knee
0.837 0.163 0.000
C18.7 Sigmoid colon
0.831 0.169 0.000
I20.9 Angina pectoris, unspecified
0.830 0.170 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.830 0.170 0.000
Z92.8 Personal history of other medical treatment
0.825 0.175 0.000
I44.7 Left bundle-branch block, unspecified
0.824 0.176 0.000
I20.8 Other forms of angina pectoris
0.824 0.176 0.000
C34 Malignant neoplasm of bronchus and lung
0.820 0.180 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.815 0.185 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.815 0.185 0.000
Z94.8 Other transplanted organ and tissue status
0.815 0.185 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.814 0.186 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.813 0.187 0.000
I24 Other acute ischaemic heart diseases
0.813 0.187 0.000
I71 Aortic aneurysm and dissection
0.812 0.188 0.000
S80-S89 Injuries to the knee and lower leg
0.809 0.191 0.000
Z48.8 Other specified surgical follow-up care
0.809 0.191 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.808 0.192 0.000
C64-C68 Malignant neoplasms of urinary tract
0.807 0.192 0.000
M72 Fibroblastic disorders
0.807 0.193 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.806 0.194 0.000
I67 Other cerebrovascular diseases
0.805 0.195 0.000
M80-M85 Disorders of bone density and structure
0.805 0.195 0.000
Chapter VII Diseases of the eye and adnexa
0.805 0.195 0.000
I49 Other cardiac arrhythmias
0.802 0.198 0.000
Z50 Care involving use of rehabilitation procedures
0.802 0.198 0.000
C77.3 Axillary and upper limb lymph nodes
0.802 0.198 0.000
Z95.3 Presence of xenogenic heart valve
0.801 0.199 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.800 0.200 0.000
Y83.4 Other reconstructive surgery
0.798 0.202 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.797 0.203 0.000
Z45.1 Adjustment and management of infusion pump
0.797 0.203 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.796 0.204 0.000
E86 Volume depletion
0.796 0.204 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.795 0.205 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.794 0.206 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.791 0.209 0.000
H61 Other disorders of external ear
0.791 0.209 0.000
E78.5 Hyperlipidaemia, unspecified
0.791 0.209 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.788 0.212 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.786 0.214 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.786 0.214 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.786 0.214 0.000
C80 Malignant neoplasm without specification of site
0.783 0.217 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.783 0.217 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.782 0.218 0.000
Z46.6 Fitting and adjustment of urinary device
0.781 0.219 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.780 0.219 0.000
I73.9 Peripheral vascular disease, unspecified
0.780 0.220 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.778 0.222 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.777 0.223 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.775 0.225 0.000
C77.2 Intra-abdominal lymph nodes
0.769 0.230 0.000
Z95.2 Presence of prosthetic heart valve
0.769 0.231 0.000
C18.0 Caecum
0.767 0.233 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.767 0.233 0.000
Z54 Convalescence
0.767 0.233 0.000
F99-F99 Unspecified mental disorder
0.766 0.234 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.766 0.234 0.000
C34.1 Upper lobe, bronchus or lung
0.764 0.236 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.763 0.237 0.000
Z45.2 Adjustment and management of vascular access device
0.762 0.238 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.762 0.238 0.000
Z80.3 Family history of malignant neoplasm of breast
0.760 0.240 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.760 0.240 0.000
I44.0 Atrioventricular block, first degree
0.758 0.242 0.000
Z49 Care involving dialysis
0.758 0.242 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.757 0.243 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.756 0.244 0.000
X50-X57 Overexertion, travel and privation
0.755 0.245 0.000
I42.0 Dilated cardiomyopathy
0.754 0.246 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.752 0.248 0.000
H30-H36 Disorders of choroid and retina
0.752 0.248 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.751 0.249 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.750 0.250 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.750 0.250 0.000
F10.2 Dependence syndrome
0.749 0.251 0.000
Z95.4 Presence of other heart-valve replacement
0.748 0.252 0.000
E04 Other non-toxic goitre
0.748 0.252 0.000
S70-S79 Injuries to the hip and thigh
0.748 0.252 0.000
W20-W49 Exposure to inanimate mechanical forces
0.747 0.253 0.000
I08 Multiple valve diseases
0.747 0.253 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.746 0.254 0.000
I25.5 Ischaemic cardiomyopathy
0.746 0.254 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.746 0.254 0.000
I67.8 Other specified cerebrovascular diseases
0.745 0.255 0.000
H80-H83 Diseases of inner ear
0.744 0.256 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.744 0.256 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.743 0.257 0.000
C18.4 Transverse colon
0.743 0.257 0.000
S90-S99 Injuries to the ankle and foot
0.743 0.257 0.000
M25 Other joint disorders, not elsewhere classified
0.742 0.258 0.000
M45-M49 Spondylopathies
0.742 0.258 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.739 0.261 0.000
F30-F39 Mood [affective] disorders
0.737 0.263 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.737 0.263 0.000
Z94.0 Kidney transplant status
0.736 0.264 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.735 0.265 0.000
C51-C58 Malignant neoplasms of female genital organs
0.733 0.267 0.000
F80-F89 Disorders of psychological development
0.733 0.267 0.000
M86-M90 Other osteopathies
0.733 0.267 0.000
Y83.3 Surgical operation with formation of external stoma
0.731 0.268 0.000
Z48.9 Surgical follow-up care, unspecified
0.730 0.270 0.000
D00-D09 In situ neoplasms
0.730 0.270 0.000
I70 Atherosclerosis
0.726 0.274 0.000
S42 Fracture of shoulder and upper arm
0.725 0.275 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.725 0.275 0.000
H33 Retinal detachments and breaks
0.724 0.276 0.000
Chapter XXII Codes for special purposes
0.722 0.278 0.000
I31 Other diseases of pericardium
0.722 0.278 0.000
E05.9 Thyrotoxicosis, unspecified
0.721 0.279 0.000
D45 Polycythaemia vera
0.721 0.279 0.000
T82.1 Mechanical complication of cardiac electronic device
0.721 0.279 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.721 0.279 0.000
I44.2 Atrioventricular block, complete
0.720 0.280 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.720 0.280 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.720 0.280 0.000
C60-C63 Malignant neoplasms of male genital organs
0.720 0.280 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.719 0.281 0.000
Z48.0 Attention to surgical dressings and sutures
0.718 0.282 0.000
Z89 Acquired absence of limb
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
M50-M54 Other dorsopathies
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
S10-S19 Injuries to the neck
0.715 0.285 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.715 0.285 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.714 0.286 0.000
T79-T79 Certain early complications of trauma
0.713 0.286 0.000
I25.6 Silent myocardial ischaemia
0.713 0.286 0.000
I25.4 Coronary artery aneurysm
0.713 0.286 0.000
I25.3 Aneurysm of heart
0.713 0.286 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.713 0.286 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.713 0.287 0.000
Z92.3 Personal history of irradiation
0.713 0.287 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.713 0.287 0.000
E88 Other metabolic disorders
0.712 0.288 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.711 0.289 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.709 0.291 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.708 0.292 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.707 0.293 0.000
M65-M68 Disorders of synovium and tendon
0.706 0.294 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.706 0.294 0.000
M21 Other acquired deformities of limbs
0.706 0.294 0.000
I52 Other heart disorders in diseases classified elsewhere
0.705 0.295 0.000
I48 Atrial fibrillation and flutter
0.705 0.295 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.705 0.295 0.000
I41 Myocarditis in diseases classified elsewhere
0.705 0.295 0.000
I40 Acute myocarditis
0.705 0.295 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.705 0.295 0.000
I37 Pulmonary valve disorders
0.705 0.295 0.000
I36 Nonrheumatic tricuspid valve disorders
0.705 0.295 0.000
I33 Acute and subacute endocarditis
0.705 0.295 0.000
I32 Pericarditis in diseases classified elsewhere
0.705 0.295 0.000
I30 Acute pericarditis
0.705 0.295 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.705 0.295 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.704 0.296 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.704 0.296 0.000
Z92.9 Personal history of medical treatment, unspecified
0.703 0.297 0.000
Z92.5 Personal history of rehabilitation measures
0.703 0.297 0.000
Z92.0 Personal history of contraception
0.703 0.297 0.000
T81 Complications of procedures, not elsewhere classified
0.702 0.298 0.000
I42.9 Cardiomyopathy, unspecified
0.701 0.299 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.701 0.299 0.000
Z45.8 Adjustment and management of other implanted devices
0.699 0.301 0.000
C79.2 Secondary malignant neoplasm of skin
0.699 0.301 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.699 0.301 0.000
I20.1 Angina pectoris with documented spasm
0.699 0.301 0.000
X60-X84 Intentional self-harm
0.698 0.302 0.000
E40-E46 Malnutrition
0.698 0.302 0.000
D41.4 Bladder
0.697 0.302 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.696 0.303 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.696 0.303 0.000
C21 Malignant neoplasm of anus and anal canal
0.696 0.303 0.000
C17 Malignant neoplasm of small intestine
0.696 0.303 0.000
C23 Malignant neoplasm of gallbladder
0.696 0.303 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.696 0.304 0.000
F70-F79 Mental retardation
0.696 0.304 0.000
F60-F69 Disorders of adult personality and behaviour
0.696 0.304 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.696 0.304 0.000
C25 Malignant neoplasm of pancreas
0.696 0.304 0.000
T87 Complications peculiar to reattachment and amputation
0.696 0.304 0.000
T86 Failure and rejection of transplanted organs and tissues
0.696 0.304 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.696 0.304 0.000
C16 Malignant neoplasm of stomach
0.695 0.305 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.695 0.305 0.000
Y35-Y36 Legal intervention and operations of war
0.695 0.305 0.000
Y10-Y34 Event of undetermined intent
0.695 0.305 0.000
Y00-Y09 Assault
0.695 0.305 0.000
X85-X99 Assault
0.695 0.305 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.695 0.305 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.695 0.305 0.000
X30-X39 Exposure to forces of nature
0.695 0.305 0.000
X20-X29 Contact with venomous animals and plants
0.695 0.305 0.000
X10-X19 Contact with heat and hot substances
0.695 0.305 0.000
X00-X09 Exposure to smoke, fire and flames
0.695 0.305 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.695 0.305 0.000
W75-W84 Other accidental threats to breathing
0.695 0.305 0.000
W65-W74 Accidental drowning and submersion
0.695 0.305 0.000
W50-W64 Exposure to animate mechanical forces
0.695 0.305 0.000
V98-V99 Other and unspecified transport accidents
0.695 0.305 0.000
V95-V97 Air and space transport accidents
0.695 0.305 0.000
V90-V94 Water transport accidents
0.695 0.305 0.000
V80-V89 Other land transport accidents
0.695 0.305 0.000
V70-V79 Bus occupant injured in transport accident
0.695 0.305 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.695 0.305 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.695 0.305 0.000
V40-V49 Car occupant injured in transport accident
0.695 0.305 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.695 0.305 0.000
V01-V09 Pedestrian injured in transport accident
0.695 0.305 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.695 0.305 0.000
I72 Other aneurysm
0.695 0.305 0.000
V20-V29 Motorcycle rider injured in transport accident
0.694 0.306 0.000
M91-M94 Chondropathies
0.692 0.308 0.000
M60-M63 Disorders of muscles
0.692 0.308 0.000
M00-M03 Infectious arthropathies
0.692 0.308 0.000
I35 Nonrheumatic aortic valve disorders
0.692 0.308 0.000
H60 Otitis externa
0.692 0.308 0.000
I62 Other nontraumatic intracranial haemorrhage
0.692 0.308 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.691 0.309 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.691 0.309 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.691 0.309 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.691 0.309 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.691 0.309 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.691 0.309 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.691 0.309 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.691 0.309 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.691 0.309 0.000
T36 Poisoning by systemic antibiotics
0.691 0.309 0.000
H61.0 Perichondritis of external ear
0.691 0.309 0.000
I42.2 Other hypertrophic cardiomyopathy
0.690 0.309 0.000
Y83.9 Surgical procedure, unspecified
0.690 0.310 0.000
M81 Osteoporosis without pathological fracture
0.690 0.310 0.000
Y83.8 Other surgical procedures
0.689 0.311 0.000
I47 Paroxysmal tachycardia
0.689 0.311 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.689 0.311 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.689 0.311 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.689 0.311 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.689 0.311 0.000
Z82.2 Family history of deafness and hearing loss
0.689 0.311 0.000
Z82.1 Family history of blindness and visual loss
0.689 0.311 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.689 0.311 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.688 0.312 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.687 0.313 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.686 0.314 0.000
E85 Amyloidosis
0.686 0.314 0.000
E84 Cystic fibrosis
0.686 0.314 0.000
E79 Disorders of purine and pyrimidine metabolism
0.686 0.314 0.000
E77 Disorders of glycoprotein metabolism
0.686 0.314 0.000
E76 Disorders of glycosaminoglycan metabolism
0.686 0.314 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.686 0.314 0.000
E74 Other disorders of carbohydrate metabolism
0.686 0.314 0.000
E73 Lactose intolerance
0.686 0.314 0.000
E72 Other disorders of amino-acid metabolism
0.686 0.314 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.686 0.314 0.000
E70 Disorders of aromatic amino-acid metabolism
0.686 0.314 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.686 0.314 0.000
M31 Other necrotising vasculopathies
0.686 0.314 0.000
Z52 Donors of organs and tissues
0.686 0.314 0.000
Z44 Fitting and adjustment of external prosthetic device
0.686 0.314 0.000
H33.2 Serous retinal detachment
0.685 0.315 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.685 0.315 0.000
S20-S29 Injuries to the thorax
0.684 0.316 0.000
I45.9 Conduction disorder, unspecified
0.683 0.317 0.000
I45.8 Other specified conduction disorders
0.683 0.317 0.000
I45.6 Preexcitation syndrome
0.683 0.317 0.000
I45.5 Other specified heart block
0.683 0.317 0.000
I45.4 Nonspecific intraventricular block
0.683 0.317 0.000
I45.3 Trifascicular block
0.683 0.317 0.000
I45.2 Bifascicular block
0.683 0.317 0.000
I45.0 Right fascicular block
0.683 0.317 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.683 0.317 0.000
C18.8 Overlapping lesion of colon
0.683 0.317 0.000
C18.6 Descending colon
0.683 0.317 0.000
C18.5 Splenic flexure
0.683 0.317 0.000
C18.3 Hepatic flexure
0.683 0.317 0.000
C18.1 Appendix
0.683 0.317 0.000
T66-T78 Other and unspecified effects of external causes
0.683 0.317 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.682 0.318 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.681 0.319 0.000
C79.6 Secondary malignant neoplasm of ovary
0.680 0.320 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.680 0.320 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.680 0.320 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.680 0.320 0.000
Z40 Prophylactic surgery
0.680 0.320 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.679 0.321 0.000
C77.9 Lymph node, unspecified
0.677 0.323 0.000
C77.4 Inguinal and lower limb lymph nodes
0.676 0.324 0.000
C77.5 Intrapelvic lymph nodes
0.675 0.325 0.000
M24 Other specific joint derangements
0.675 0.325 0.000
C77.0 Lymph nodes of head, face and neck
0.674 0.326 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.674 0.326 0.000
I49.4 Other and unspecified premature depolarisation
0.673 0.327 0.000
S50-S59 Injuries to the elbow and forearm
0.673 0.327 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.673 0.327 0.000
C78.7 Secondary malignant neoplasm of liver
0.672 0.328 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.672 0.328 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.672 0.328 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.672 0.328 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.672 0.328 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.672 0.328 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.672 0.328 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.672 0.328 0.000
F11 Mental and behavioural disorders due to use of opioids
0.672 0.328 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.671 0.329 0.000
V10-V19 Pedal cyclist injured in transport accident
0.671 0.329 0.000
Z93 Artificial opening status
0.670 0.330 0.000
Z88.0 Personal history of allergy to penicillin
0.670 0.330 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.670 0.330 0.000
E78.8 Other disorders of lipoprotein metabolism
0.670 0.330 0.000
E78.6 Lipoprotein deficiency
0.670 0.330 0.000
E78.4 Other hyperlipidaemia
0.670 0.330 0.000
E78.3 Hyperchylomicronaemia
0.670 0.330 0.000
E78.2 Mixed hyperlipidaemia
0.670 0.330 0.000
E78.1 Pure hyperglyceridaemia
0.670 0.330 0.000
M22 Disorders of patella
0.669 0.331 0.000
Z29 Need for other prophylactic measures
0.669 0.331 0.000
Y95 Nosocomial condition
0.669 0.331 0.000
C34.2 Middle lobe, bronchus or lung
0.668 0.332 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.668 0.332 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.668 0.332 0.000
D46 Myelodysplastic syndromes
0.668 0.332 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.668 0.332 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.668 0.332 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.668 0.332 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.668 0.332 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.668 0.332 0.000
E50-E64 Other nutritional deficiencies
0.666 0.333 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.665 0.335 0.000
F29 Unspecified nonorganic psychosis
0.665 0.335 0.000
C18.2 Ascending colon
0.665 0.335 0.000
Z50.2 Alcohol rehabilitation
0.665 0.335 0.000
H65-H75 Diseases of middle ear and mastoid
0.664 0.335 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.664 0.336 0.000
I74 Arterial embolism and thrombosis
0.663 0.337 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.663 0.337 0.000
Z43 Attention to artificial openings
0.662 0.338 0.000
C78.2 Secondary malignant neoplasm of pleura
0.662 0.338 0.000
Chapter I Certain infectious and parasitic diseases
0.660 0.340 0.000
C77.8 Lymph nodes of multiple regions
0.660 0.340 0.000
C77.1 Intrathoracic lymph nodes
0.659 0.341 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.658 0.341 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.658 0.342 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.658 0.342 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.657 0.343 0.000
Z97 Presence of other devices
0.657 0.343 0.000
I44.6 Other and unspecified fascicular block
0.656 0.344 0.000
I44.5 Left posterior fascicular block
0.656 0.344 0.000
I44.4 Left anterior fascicular block
0.656 0.344 0.000
I44.3 Other and unspecified atrioventricular block
0.656 0.344 0.000
C67 Malignant neoplasm of bladder
0.656 0.344 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.653 0.347 0.000
Z94.9 Transplanted organ and tissue status, unspecified
0.653 0.347 0.000
Z94.7 Corneal transplant status
0.653 0.347 0.000
Z94.6 Bone transplant status
0.653 0.347 0.000
Z94.5 Skin transplant status
0.653 0.347 0.000
Z94.4 Liver transplant status
0.653 0.347 0.000
Z94.3 Heart and lungs transplant status
0.653 0.347 0.000
Z94.2 Lung transplant status
0.653 0.347 0.000
Z94.1 Heart transplant status
0.653 0.347 0.000
F10.9 Unspecified mental and behavioural disorder
0.652 0.348 0.000
F10.8 Other mental and behavioural disorders
0.652 0.348 0.000
F10.7 Residual and late-onset psychotic disorder
0.652 0.348 0.000
F10.6 Amnesic syndrome
0.652 0.348 0.000
F10.5 Psychotic disorder
0.652 0.348 0.000
F10.4 Withdrawal state with delirium
0.652 0.348 0.000
C50-C50 Malignant neoplasm of breast
0.652 0.348 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.651 0.349 0.000
M40-M43 Deforming dorsopathies
0.650 0.349 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.650 0.350 0.000
H61.2 Impacted cerumen
0.649 0.351 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.649 0.351 0.000
I61 Intracerebral haemorrhage
0.649 0.351 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.648 0.352 0.000
Z57 Occupational exposure to risk-factors
0.648 0.352 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.648 0.352 0.000
M79.6 Pain in limb
0.647 0.353 0.000
H33.0 Retinal detachment with retinal break
0.647 0.353 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.647 0.353 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.646 0.354 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.646 0.354 0.000
Z80.6 Family history of leukaemia
0.646 0.354 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.646 0.354 0.000
Z98 Other postsurgical states
0.646 0.354 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.645 0.355 0.000
M34 Systemic sclerosis
0.645 0.355 0.000
M33 Dermatopolymyositis
0.645 0.355 0.000
M32 Systemic lupus erythematosus
0.645 0.355 0.000
M30 Polyarteritis nodosa and related conditions
0.645 0.355 0.000
E03 Other hypothyroidism
0.645 0.355 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.645 0.355 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.645 0.355 0.000
T39.4 Antirheumatics, not elsewhere classified
0.645 0.355 0.000
T39.2 Pyrazolone derivatives
0.645 0.355 0.000
F20 Schizophrenia
0.644 0.355 0.000
D50-D53 Nutritional anaemias
0.644 0.355 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.644 0.356 0.000
Z45.3 Adjustment and management of implanted hearing device
0.644 0.356 0.000
Z91.5 Personal history of self-harm
0.642 0.358 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.642 0.358 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.642 0.358 0.000
C32 Malignant neoplasm of larynx
0.642 0.358 0.000
C31 Malignant neoplasm of accessory sinuses
0.642 0.358 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.642 0.358 0.000
C37 Malignant neoplasm of thymus
0.642 0.358 0.000
C33 Malignant neoplasm of trachea
0.642 0.358 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.642 0.358 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.642 0.358 0.000
M77 Other enthesopathies
0.641 0.359 0.000
M76 Enthesopathies of lower limb, excluding foot
0.641 0.359 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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