TreeWAS – Variant ID: rs78288301

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter II Neoplasms	1.000	0.000
# Top node	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.999	0.001
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.998	0.002
M20-M25 Other joint disorders	0.998	0.002
Chapter XI Diseases of the digestive system	0.997	0.003
D50 Iron deficiency anaemia	0.997	0.003
D50-D53 Nutritional anaemias	0.997	0.003
D50.9 Iron deficiency anaemia, unspecified	0.996	0.004
C15-C26 Malignant neoplasms of digestive organs	0.996	0.004
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.995	0.005
M05-M14 Inflammatory polyarthropathies	0.995	0.005
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.990	0.010
C18 Malignant neoplasm of colon	0.988	0.012
M06 Other rheumatoid arthritis	0.987	0.013
Chapter I Certain infectious and parasitic diseases	0.984	0.016
M35 Other systemic involvement of connective tissue	0.982	0.018
Chapter V Mental and behavioural disorders	0.980	0.020
K70-K77 Diseases of liver	0.979	0.021
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.977	0.023
M06.9 Rheumatoid arthritis, unspecified	0.977	0.023
S00-S09 Injuries to the head	0.976	0.024
C78.0 Secondary malignant neoplasm of lung	0.972	0.028
K70 Alcoholic liver disease	0.969	0.031
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.962	0.038
D37-D48 Neoplasms of uncertain or unknown behaviour	0.962	0.038
K70.9 Alcoholic liver disease, unspecified	0.952	0.048
K04 Diseases of pulp and periapical tissues	0.948	0.052
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.946	0.054
M35.3 Polymyalgia rheumatica	0.945	0.055
F40-F48 Neurotic, stress-related and somatoform disorders	0.942	0.058
B95-B98 Bacterial, viral and other infectious agents	0.941	0.059
C18.7 Sigmoid colon	0.938	0.062
M70-M79 Other soft tissue disorders	0.937	0.063
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.934	0.066
Chapter XX External causes of morbidity and mortality	0.930	0.070
K11 Diseases of salivary glands	0.930	0.070
C78.7 Secondary malignant neoplasm of liver	0.929	0.071
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.928	0.072
C34 Malignant neoplasm of bronchus and lung	0.918	0.082
C25 Malignant neoplasm of pancreas	0.916	0.084
K08 Other disorders of teeth and supporting structures	0.913	0.087
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.911	0.089
M23 Internal derangement of knee	0.911	0.089
K82 Other diseases of gallbladder	0.907	0.093
K86 Other diseases of pancreas	0.906	0.094
M79 Other soft tissue disorders, not elsewhere classified	0.901	0.099
M35.0 Sicca syndrome [Sjogren]	0.901	0.099
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.899	0.101
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.898	0.102
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.898	0.102
S02 Fracture of skull and facial bones	0.897	0.103
F10 Mental and behavioural disorders due to use of alcohol	0.894	0.106
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.893	0.107
K72 Hepatic failure, not elsewhere classified	0.884	0.116
M13 Other arthritis	0.884	0.116
S00 Superficial injury of head	0.883	0.117
M25 Other joint disorders, not elsewhere classified	0.882	0.118
T66-T78 Other and unspecified effects of external causes	0.875	0.125
K04.5 Chronic apical periodontitis	0.872	0.128
K04.6 Periapical abscess with sinus	0.872	0.128
Chapter VIII Diseases of the ear and mastoid process	0.871	0.129
M23.2 Derangement of meniscus due to old tear or injury	0.868	0.132
K01 Embedded and impacted teeth	0.868	0.132
Chapter X Diseases of the respiratory system	0.866	0.134
S60-S69 Injuries to the wrist and hand	0.866	0.134
C77.2 Intra-abdominal lymph nodes	0.864	0.136
C18.2 Ascending colon	0.864	0.136
F41 Other anxiety disorders	0.862	0.138
C34.9 Bronchus or lung, unspecified	0.860	0.140
M79.8 Other specified soft tissue disorders	0.858	0.142
S80-S89 Injuries to the knee and lower leg	0.852	0.148
K11.5 Sialolithiasis	0.850	0.150
C80 Malignant neoplasm without specification of site	0.849	0.151
M06.0 Seronegative rheumatoid arthritis	0.840	0.160
C77.9 Lymph node, unspecified	0.840	0.160
K12 Stomatitis and related lesions	0.838	0.162
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.837	0.163
C78.4 Secondary malignant neoplasm of small intestine	0.832	0.168
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.832	0.168
M24 Other specific joint derangements	0.831	0.169
S01 Open wound of head	0.830	0.170
C18.9 Colon, unspecified	0.830	0.170
M91-M94 Chondropathies	0.829	0.170
M79.86 Other specified soft tissue disorders (Lower leg)	0.825	0.175
C18.0 Caecum	0.824	0.176
D80-D89 Certain disorders involving the immune mechanism	0.823	0.177
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.820	0.180
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.820	0.180
C77.8 Lymph nodes of multiple regions	0.819	0.181
K80 Cholelithiasis	0.818	0.182
C21 Malignant neoplasm of anus and anal canal	0.817	0.182
B15-B19 Viral hepatitis	0.817	0.183
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.817	0.183
K72.9 Hepatic failure, unspecified	0.816	0.184
C34.3 Lower lobe, bronchus or lung	0.816	0.184
T51 Toxic effect of alcohol	0.815	0.185
F41.2 Mixed anxiety and depressive disorder	0.814	0.186
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.812	0.188
K86.1 Other chronic pancreatitis	0.810	0.190
F45 Somatoform disorders	0.809	0.190
F43 Reaction to severe stress, and adjustment disorders	0.808	0.192
M60-M63 Disorders of muscles	0.806	0.194
C18.3 Hepatic flexure	0.805	0.195
K04.8 Radicular cyst	0.805	0.195
M20 Acquired deformities of fingers and toes	0.804	0.196
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.803	0.197
A00-A09 Intestinal infectious diseases	0.802	0.198
D00-D09 In situ neoplasms	0.799	0.201
J80-J84 Other respiratory diseases principally affecting the interstitium	0.798	0.202
A30-A49 Other bacterial diseases	0.797	0.203
S00.2 Other superficial injuries of eyelid and periocular area	0.797	0.203
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.797	0.203
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.796	0.204
D46 Myelodysplastic syndromes	0.796	0.204
C32 Malignant neoplasm of larynx	0.793	0.207
M13.9 Arthritis, unspecified	0.791	0.209
F10.3 Withdrawal state	0.789	0.211
K70.4 Alcoholic hepatic failure	0.789	0.211
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.788	0.212
D45 Polycythaemia vera	0.787	0.213
T78 Adverse effects, not elsewhere classified	0.786	0.214
T15-T19 Effects of foreign body entering through natural orifice	0.786	0.214
K82.4 Cholesterolosis of gallbladder	0.785	0.215
K08.3 Retained dental root	0.785	0.215
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.782	0.218
C16 Malignant neoplasm of stomach	0.781	0.219
K11.6 Mucocele of salivary gland	0.781	0.219
F10.2 Dependence syndrome	0.779	0.221
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.779	0.221
S06 Intracranial injury	0.778	0.222
M25.8 Other specified joint disorders	0.777	0.223
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.777	0.223
M05 Seropositive rheumatoid arthritis	0.776	0.224
C25.2 Tail of pancreas	0.775	0.225
K82.8 Other specified diseases of gallbladder	0.775	0.225
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.774	0.226
D50.8 Other iron deficiency anaemias	0.771	0.229
S50-S59 Injuries to the elbow and forearm	0.771	0.229
W00-W19 Falls	0.770	0.230
C77.1 Intrathoracic lymph nodes	0.768	0.232
K01.1 Impacted teeth	0.767	0.233
S00.9 Superficial injury of head, part unspecified	0.767	0.233
F99-F99 Unspecified mental disorder	0.766	0.234
M79.0 Rheumatism, unspecified	0.765	0.235
C15 Malignant neoplasm of oesophagus	0.765	0.235
S10-S19 Injuries to the neck	0.765	0.235
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.764	0.236
A50-A64 Infections with a predominantly sexual mode of transmission	0.763	0.237
Q60-Q64 Congenital malformations of the urinary system	0.758	0.242
J40-J47 Chronic lower respiratory diseases	0.756	0.244
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.756	0.244
C25.0 Head of pancreas	0.756	0.244
D10-D36 Benign neoplasms	0.755	0.245
M86-M90 Other osteopathies	0.755	0.245
T51.0 Ethanol	0.755	0.245
K70.1 Alcoholic hepatitis	0.754	0.246
C18.4 Transverse colon	0.754	0.246
W20-W49 Exposure to inanimate mechanical forces	0.753	0.247
C64-C68 Malignant neoplasms of urinary tract	0.751	0.249
K08.9 Disorder of teeth and supporting structures, unspecified	0.749	0.251
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.749	0.251
M21 Other acquired deformities of limbs	0.747	0.252
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.747	0.253
C25.9 Pancreas, unspecified	0.747	0.253
S02.2 Fracture of nasal bones	0.746	0.254
S90-S99 Injuries to the ankle and foot	0.746	0.254
S02.8 Fractures of other skull and facial bones	0.745	0.255
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.744	0.256
D12.3 Transverse colon	0.744	0.256
S64 Injury of nerves at wrist and hand level	0.743	0.257
Y95 Nosocomial condition	0.742	0.258
J84 Other interstitial pulmonary diseases	0.739	0.261
M80-M85 Disorders of bone density and structure	0.738	0.262
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.738	0.262
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.738	0.262
K86.9 Disease of pancreas, unspecified	0.737	0.263
K09 Cysts of oral region, not elsewhere classified	0.737	0.263
C26 Malignant neoplasm of other and ill-defined digestive organs	0.737	0.263
K70.3 Alcoholic cirrhosis of liver	0.736	0.264
C80.9 Malignant neoplasm, unspecified	0.736	0.264
M70 Soft tissue disorders related to use, overuse and pressure	0.736	0.264
S05 Injury of eye and orbit	0.735	0.265
K10 Other diseases of jaws	0.735	0.265
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.734	0.266
Y60-Y69 Misadventures to patients during surgical and medical care	0.733	0.266
K00 Disorders of tooth development and eruption	0.732	0.268
S02.5 Fracture of tooth	0.731	0.269
S20-S29 Injuries to the thorax	0.731	0.269
K12.3 Oral mucositis (ulcerative)	0.729	0.271
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.728	0.272
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.724	0.276
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.724	0.276
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.722	0.278
J47 Bronchiectasis	0.722	0.278
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.722	0.278
F17 Mental and behavioural disorders due to use of tobacco	0.721	0.279
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.719	0.281
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.719	0.281
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.719	0.281
J00-J06 Acute upper respiratory infections	0.719	0.281
M77 Other enthesopathies	0.719	0.281
M79.7 Fibromyalgia	0.718	0.282
K81 Cholecystitis	0.718	0.282
T36-T50 Poisoning by drugs, medicaments and biological substances	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
S70-S79 Injuries to the hip and thigh	0.716	0.284
T33-T35 Frostbite	0.716	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.284
T00-T07 Injuries involving multiple body regions	0.716	0.284
C76 Malignant neoplasm of other and ill-defined sites	0.716	0.284
D55-D59 Haemolytic anaemias	0.715	0.285
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.715	0.285
M34 Systemic sclerosis	0.715	0.285
M33 Dermatopolymyositis	0.715	0.285
M32 Systemic lupus erythematosus	0.715	0.285
M30 Polyarteritis nodosa and related conditions	0.715	0.285
K02 Dental caries	0.715	0.285
D50.1 Sideropenic dysphagia	0.715	0.285
D53 Other nutritional anaemias	0.715	0.285
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.714	0.286
F45.8 Other somatoform disorders	0.714	0.286
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.714	0.286
C17 Malignant neoplasm of small intestine	0.714	0.286
C23 Malignant neoplasm of gallbladder	0.714	0.286
K03 Other diseases of hard tissues of teeth	0.714	0.286
M14 Arthropathies in other diseases classified elsewhere	0.713	0.287
M12 Other specific arthropathies	0.713	0.287
M09 Juvenile arthritis in diseases classified elsewhere	0.713	0.287
M08 Juvenile arthritis	0.713	0.287
F10.9 Unspecified mental and behavioural disorder	0.713	0.287
S00.7 Multiple superficial injuries of head	0.711	0.289
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.709	0.290
C78.1 Secondary malignant neoplasm of mediastinum	0.709	0.290
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.709	0.291
C18.8 Overlapping lesion of colon	0.708	0.291
C18.1 Appendix	0.708	0.291
W50-W64 Exposure to animate mechanical forces	0.708	0.292
M06.8 Other specified rheumatoid arthritis	0.708	0.292
M06.4 Inflammatory polyarthropathy	0.708	0.292
M06.3 Rheumatoid nodule	0.708	0.292
M06.2 Rheumatoid bursitis	0.708	0.292
M06.1 Adult-onset Still's disease	0.708	0.292
D52 Folate deficiency anaemia	0.707	0.293
K80.4 Calculus of bile duct with cholecystitis	0.706	0.294
B99-B99 Other infectious diseases	0.705	0.295
B90-B94 Sequelae of infectious and parasitic diseases	0.705	0.295
B85-B89 Pediculosis, acariasis and other infestations	0.705	0.295
B65-B83 Helminthiases	0.705	0.295
B50-B64 Protozoal diseases	0.705	0.295
B20-B24 Human immunodeficiency virus [HIV] disease	0.705	0.295
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.705	0.295
A75-A79 Rickettsioses	0.705	0.295
A70-A74 Other diseases caused by chlamydiae	0.705	0.295
A65-A69 Other spirochaetal diseases	0.705	0.295
A20-A28 Certain zoonotic bacterial diseases	0.705	0.295
A15-A19 Tuberculosis	0.705	0.295
Q38-Q45 Other congenital malformations of the digestive system	0.705	0.295
K80.1 Calculus of gallbladder with other cholecystitis	0.705	0.295
M20.1 Hallux valgus (acquired)	0.704	0.296
M35.9 Systemic involvement of connective tissue, unspecified	0.704	0.296
M35.8 Other specified systemic involvement of connective tissue	0.704	0.296
M35.7 Hypermobility syndrome	0.704	0.296
M35.6 Relapsing panniculitis [Weber-Christian]	0.704	0.296
M35.5 Multifocal fibrosclerosis	0.704	0.296
M35.4 Diffuse (eosinophilic) fasciitis	0.704	0.296
M35.2 Behcet's disease	0.704	0.296
M35.1 Other overlap syndromes	0.704	0.296
M72 Fibroblastic disorders	0.704	0.296
F60-F69 Disorders of adult personality and behaviour	0.703	0.297
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.702	0.298
F70-F79 Mental retardation	0.702	0.298
K77 Liver disorders in diseases classified elsewhere	0.702	0.298
K73 Chronic hepatitis, not elsewhere classified	0.702	0.298
K71 Toxic liver disease	0.702	0.298
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.701	0.299
S60 Superficial injury of wrist and hand	0.701	0.299
M06.98 Rheumatoid arthritis, unspecified (Other)	0.700	0.300
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.700	0.300
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.700	0.300
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.700	0.300
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.700	0.300
M13.96 Arthritis, unspecified (Lower leg)	0.700	0.300
K14 Diseases of tongue	0.700	0.300
S08 Traumatic amputation of part of head	0.700	0.300
S07 Crushing injury of head	0.700	0.300
S04 Injury of cranial nerves	0.700	0.300
S03 Dislocation, sprain and strain of joints and ligaments of head	0.700	0.300
D68 Other coagulation defects	0.698	0.302
M79.84 Other specified soft tissue disorders (Hand)	0.697	0.303
K82.9 Disease of gallbladder, unspecified	0.697	0.303
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.696	0.304
K08.8 Other specified disorders of teeth and supporting structures	0.696	0.304
K05 Gingivitis and periodontal diseases	0.696	0.304
K70.2 Alcoholic fibrosis and sclerosis of liver	0.695	0.305
K70.0 Alcoholic fatty liver	0.695	0.305
T78.3 Angioneurotic oedema	0.694	0.306
M65-M68 Disorders of synovium and tendon	0.693	0.307
M13.94 Arthritis, unspecified (Hand)	0.693	0.307
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.693	0.307
F10.0 Acute intoxication	0.692	0.308
S02.1 Fracture of base of skull	0.691	0.309
F42 Obsessive-compulsive disorder	0.691	0.309
S01.1 Open wound of eyelid and periocular area	0.691	0.309
K11.9 Disease of salivary gland, unspecified	0.691	0.309
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.690	0.310
V40-V49 Car occupant injured in transport accident	0.690	0.310
M13.99 Arthritis, unspecified (Site unspecified)	0.690	0.310
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.690	0.310
C38 Malignant neoplasm of heart, mediastinum and pleura	0.690	0.310
C31 Malignant neoplasm of accessory sinuses	0.690	0.310
C30 Malignant neoplasm of nasal cavity and middle ear	0.690	0.310
C37 Malignant neoplasm of thymus	0.690	0.310
C33 Malignant neoplasm of trachea	0.690	0.310
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.689	0.310
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.689	0.310
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.689	0.310
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.689	0.310
K74 Fibrosis and cirrhosis of liver	0.689	0.311
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.689	0.311
T79-T79 Certain early complications of trauma	0.688	0.312
H65-H75 Diseases of middle ear and mastoid	0.687	0.312
K86.0 Alcohol-induced chronic pancreatitis	0.687	0.313
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.687	0.313
K83 Other diseases of biliary tract	0.687	0.313
A80-A89 Viral infections of the central nervous system	0.687	0.313
S02.3 Fracture of orbital floor	0.686	0.313
F80-F89 Disorders of psychological development	0.686	0.314
H90-H95 Other disorders of ear	0.686	0.314
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.686	0.314
S51 Open wound of forearm	0.686	0.314
H80-H83 Diseases of inner ear	0.685	0.315
C78.2 Secondary malignant neoplasm of pleura	0.684	0.316
Q80-Q89 Other congenital malformations	0.684	0.316
C79 Secondary malignant neoplasm of other sites	0.683	0.317
F43.0 Acute stress reaction	0.682	0.318
B15 Acute hepatitis A	0.681	0.319
T59 Toxic effect of other gases, fumes and vapours	0.680	0.320
K04.4 Acute apical periodontitis of pulpal origin	0.680	0.320
K04.3 Abnormal hard tissue formation in pulp	0.680	0.320
K04.2 Pulp degeneration	0.680	0.320
K04.1 Necrosis of pulp	0.680	0.320
K04.0 Pulpitis	0.680	0.320
M07 Psoriatic and enteropathic arthropathies	0.680	0.320
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.680	0.320
Chapter XXII Codes for special purposes	0.679	0.321
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.679	0.321
S01.2 Open wound of nose	0.679	0.321
M79.5 Residual foreign body in soft tissue	0.678	0.322
D46.9 Myelodysplastic syndrome, unspecified	0.677	0.323
D89.2 Hypergammaglobulinaemia, unspecified	0.677	0.323
M25.5 Pain in joint	0.677	0.323
F48 Other neurotic disorders	0.676	0.324
F44 Dissociative [conversion] disorders	0.676	0.324
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.675	0.325
D12.2 Ascending colon	0.675	0.325
M76 Enthesopathies of lower limb, excluding foot	0.672	0.328
M73 Soft tissue disorders in diseases classified elsewhere	0.672	0.328
V10-V19 Pedal cyclist injured in transport accident	0.671	0.328
S00.0 Superficial injury of scalp	0.671	0.329
M23.4 Loose body in knee	0.671	0.329
M24.0 Loose body in joint	0.670	0.330
X40-X49 Accidental poisoning by and exposure to noxious substances	0.670	0.330
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.670	0.330
F18 Mental and behavioural disorders due to use of volatile solvents	0.670	0.330
F16 Mental and behavioural disorders due to use of hallucinogens	0.670	0.330
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.670	0.330
F14 Mental and behavioural disorders due to use of cocaine	0.670	0.330
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.670	0.330
F12 Mental and behavioural disorders due to use of cannabinoids	0.670	0.330
F11 Mental and behavioural disorders due to use of opioids	0.670	0.330
D04 Carcinoma in situ of skin	0.670	0.330
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.669	0.330
C18.5 Splenic flexure	0.669	0.331
M13.0 Polyarthritis, unspecified	0.669	0.331
K86.2 Cyst of pancreas	0.668	0.331
S40-S49 Injuries to the shoulder and upper arm	0.668	0.332
K86.8 Other specified diseases of pancreas	0.667	0.332
M25.3 Other instability of joint	0.667	0.332
D09 Carcinoma in situ of other and unspecified sites	0.667	0.333
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.667	0.333
Y35-Y36 Legal intervention and operations of war	0.667	0.333
Y10-Y34 Event of undetermined intent	0.667	0.333
Y00-Y09 Assault	0.667	0.333
X85-X99 Assault	0.667	0.333
X58-X59 Accidental exposure to other and unspecified factors	0.667	0.333
X50-X57 Overexertion, travel and privation	0.667	0.333
X30-X39 Exposure to forces of nature	0.667	0.333
X20-X29 Contact with venomous animals and plants	0.667	0.333
X10-X19 Contact with heat and hot substances	0.667	0.333
X00-X09 Exposure to smoke, fire and flames	0.667	0.333
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.667	0.333
W75-W84 Other accidental threats to breathing	0.667	0.333
W65-W74 Accidental drowning and submersion	0.667	0.333
V98-V99 Other and unspecified transport accidents	0.667	0.333
V95-V97 Air and space transport accidents	0.667	0.333
V90-V94 Water transport accidents	0.667	0.333
V80-V89 Other land transport accidents	0.667	0.333
V70-V79 Bus occupant injured in transport accident	0.667	0.333
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.667	0.333
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.667	0.333
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.667	0.333
V01-V09 Pedestrian injured in transport accident	0.667	0.333
K11.8 Other diseases of salivary glands	0.666	0.333
K11.7 Disturbances of salivary secretion	0.666	0.333
K11.4 Fistula of salivary gland	0.666	0.333
K11.3 Abscess of salivary gland	0.666	0.333
K11.1 Hypertrophy of salivary gland	0.666	0.333
K11.0 Atrophy of salivary gland	0.666	0.333
S80 Superficial injury of lower leg	0.665	0.335
C34.0 Main bronchus	0.665	0.335
Q50-Q56 Congenital malformations of genital organs	0.665	0.335
C77.5 Intrapelvic lymph nodes	0.665	0.335
K06 Other disorders of gingiva and edentulous alveolar ridge	0.663	0.337
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.663	0.337
C21.0 Anus, unspecified	0.662	0.338
M94 Other disorders of cartilage	0.661	0.339
C77.4 Inguinal and lower limb lymph nodes	0.661	0.339
M31 Other necrotising vasculopathies	0.660	0.340
F41.1 Generalised anxiety disorder	0.660	0.340
D48.0 Bone and articular cartilage	0.659	0.340
S01.4 Open wound of cheek and temporomandibular area	0.659	0.340
M10 Gout	0.659	0.341
B97 Viral agents as the cause of diseases classified to other chapters	0.659	0.341
M93 Other osteochondropathies	0.659	0.341
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.659	0.341
C18.6 Descending colon	0.658	0.342
C34.8 Overlapping lesion of bronchus and lung	0.658	0.342
C34.2 Middle lobe, bronchus or lung	0.658	0.342
K82.1 Hydrops of gallbladder	0.658	0.342
S01.9 Open wound of head, part unspecified	0.658	0.342
F10.4 Withdrawal state with delirium	0.657	0.343
C25.8 Overlapping lesion of pancreas	0.657	0.343
C25.7 Other parts of pancreas	0.657	0.343
C25.4 Endocrine pancreas	0.657	0.343
C25.3 Pancreatic duct	0.657	0.343
C25.1 Body of pancreas	0.657	0.343
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.657	0.343
M20.4 Other hammer toe(s) (acquired)	0.656	0.344
M11 Other crystal arthropathies	0.656	0.344
K08.2 Atrophy of edentulous alveolar ridge	0.654	0.345
K08.0 Exfoliation of teeth due to systemic causes	0.654	0.345
S89 Other and unspecified injuries of lower leg	0.654	0.345
K12.0 Recurrent oral aphthae	0.654	0.346
M23.9 Internal derangement of knee, unspecified	0.653	0.347
M23.6 Other spontaneous disruption of ligament(s) of knee	0.653	0.347
M23.5 Chronic instability of knee	0.653	0.347
M23.1 Discoid meniscus (congenital)	0.653	0.347
M23.0 Cystic meniscus	0.653	0.347
M25.6 Stiffness of joint, not elsewhere classified	0.653	0.347
M79.09 Rheumatism, unspecified (Site unspecified)	0.652	0.348
J90-J94 Other diseases of pleura	0.652	0.348
M60 Myositis	0.651	0.349
K82.3 Fistula of gallbladder	0.651	0.349
K82.2 Perforation of gallbladder	0.651	0.349
K82.0 Obstruction of gallbladder	0.651	0.349
F41.9 Anxiety disorder, unspecified	0.651	0.349
Y52 Agents primarily affecting the cardiovascular system	0.650	0.350
K07 Dentofacial anomalies [including malocclusion]	0.649	0.351
H60-H62 Diseases of external ear	0.648	0.352
D12.0 Caecum	0.648	0.352
K01.0 Embedded teeth	0.648	0.352
M24.8 Other specific joint derangements, not elsewhere classified	0.647	0.353
Y48 Anaesthetics and therapeutic gases	0.646	0.353
M79.9 Soft tissue disorder, unspecified	0.646	0.354
M79.4 Hypertrophy of (infrapatellar) fat pad	0.646	0.354
M79.3 Panniculitis, unspecified	0.646	0.354
M79.2 Neuralgia and neuritis, unspecified	0.646	0.354
M79.1 Myalgia	0.646	0.354
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.645	0.354
B07 Viral warts	0.645	0.355
C32.1 Supraglottis	0.644	0.355
T65 Toxic effect of other and unspecified substances	0.644	0.356
T63 Toxic effect of contact with venomous animals	0.644	0.356
T62 Toxic effect of other noxious substances eaten as food	0.644	0.356
T61 Toxic effect of noxious substances eaten as seafood	0.644	0.356
T60 Toxic effect of pesticides	0.644	0.356
T57 Toxic effect of other inorganic substances	0.644	0.356
T56 Toxic effect of metals	0.644	0.356
T54 Toxic effect of corrosive substances	0.644	0.356
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.644	0.356
T52 Toxic effect of organic solvents	0.644	0.356
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.644	0.356
T58 Toxic effect of carbon monoxide	0.644	0.356
T55 Toxic effect of soaps and detergents	0.644	0.356
Chapter IV Endocrine, nutritional and metabolic diseases	0.644	0.356
S02.9 Fracture of skull and facial bones, part unspecified	0.643	0.356
S02.7 Multiple fractures involving skull and facial bones	0.643	0.356
S02.0 Fracture of vault of skull	0.643	0.357
A08 Viral and other specified intestinal infections	0.643	0.357
V20-V29 Motorcycle rider injured in transport accident	0.642	0.358
D48.1 Connective and other soft tissue	0.642	0.358
F10.8 Other mental and behavioural disorders	0.641	0.359
F10.7 Residual and late-onset psychotic disorder	0.641	0.359

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations