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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs785427
log Bayes Factor = 9.18741
Chromosome 15   position 30,182,766  (GRCh37) Explore rs785427 on Ensembl!
Variant rs785427 is part of Cluster X0018

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.997 0.003 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.992 0.008 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.992 0.008 0.000
E70-E90 Metabolic disorders
0.992 0.008 0.000
M20-M25 Other joint disorders
0.991 0.009 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.989 0.011 0.000
S50-S59 Injuries to the elbow and forearm
0.986 0.014 0.000
Chapter I Certain infectious and parasitic diseases
0.984 0.016 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.972 0.028 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.971 0.029 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.971 0.029 0.000
B95-B98 Bacterial, viral and other infectious agents
0.965 0.035 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.964 0.036 0.000
S20-S29 Injuries to the thorax
0.964 0.036 0.000
E87.6 Hypokalaemia
0.962 0.038 0.000
S00-S09 Injuries to the head
0.962 0.038 0.000
Y42.7 Androgens and anabolic congeners
0.961 0.039 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.955 0.045 0.000
M23 Internal derangement of knee
0.954 0.046 0.000
E20-E35 Disorders of other endocrine glands
0.950 0.050 0.000
S51 Open wound of forearm
0.949 0.051 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.944 0.056 0.000
M23.3 Other meniscus derangements
0.943 0.057 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.940 0.060 0.000
T43.2 Other and unspecified antidepressants
0.936 0.064 0.000
S00 Superficial injury of head
0.933 0.067 0.000
T39.1 4-Aminophenol derivatives
0.930 0.070 0.000
S27 Injury of other and unspecified intrathoracic organs
0.927 0.073 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.926 0.074 0.000
E87.0 Hyperosmolality and hypernatraemia
0.925 0.075 0.000
S00.8 Superficial injury of other parts of head
0.925 0.075 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.922 0.078 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.922 0.078 0.000
M22 Disorders of patella
0.921 0.079 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.919 0.081 0.000
E27 Other disorders of adrenal gland
0.916 0.084 0.000
E87.7 Fluid overload
0.914 0.086 0.000
Chapter VI Diseases of the nervous system
0.913 0.087 0.000
S60-S69 Injuries to the wrist and hand
0.913 0.087 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.913 0.087 0.000
Y52 Agents primarily affecting the cardiovascular system
0.913 0.087 0.000
M24 Other specific joint derangements
0.911 0.089 0.000
M70-M79 Other soft tissue disorders
0.910 0.090 0.000
M05-M14 Inflammatory polyarthropathies
0.908 0.092 0.000
S51.9 Open wound of forearm, part unspecified
0.906 0.094 0.000
T58 Toxic effect of carbon monoxide
0.894 0.106 0.000
E85 Amyloidosis
0.892 0.108 0.000
M22.2 Patellofemoral disorders
0.891 0.109 0.000
T79-T79 Certain early complications of trauma
0.889 0.111 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.886 0.114 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.883 0.117 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.873 0.127 0.000
G40-G47 Episodic and paroxysmal disorders
0.872 0.128 0.000
M05 Seropositive rheumatoid arthritis
0.865 0.135 0.000
T51 Toxic effect of alcohol
0.863 0.137 0.000
B15-B19 Viral hepatitis
0.862 0.138 0.000
M75 Shoulder lesions
0.858 0.142 0.000
S27.0 Traumatic pneumothorax
0.855 0.145 0.000
A00-A09 Intestinal infectious diseases
0.853 0.147 0.000
E50-E64 Other nutritional deficiencies
0.850 0.150 0.000
M65-M68 Disorders of synovium and tendon
0.849 0.151 0.000
S52 Fracture of forearm
0.841 0.159 0.000
Q50-Q56 Congenital malformations of genital organs
0.837 0.163 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.835 0.165 0.000
M75.5 Bursitis of shoulder
0.835 0.165 0.000
S05 Injury of eye and orbit
0.834 0.166 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.832 0.168 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.831 0.169 0.000
S32 Fracture of lumbar spine and pelvis
0.831 0.169 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.830 0.170 0.000
M24.0 Loose body in joint
0.828 0.172 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.827 0.173 0.000
S10-S19 Injuries to the neck
0.827 0.173 0.000
X20-X29 Contact with venomous animals and plants
0.826 0.174 0.000
M75.0 Adhesive capsulitis of shoulder
0.823 0.177 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.821 0.179 0.000
S90-S99 Injuries to the ankle and foot
0.817 0.183 0.000
Y43 Primarily systemic agents
0.816 0.184 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.816 0.184 0.000
S00.9 Superficial injury of head, part unspecified
0.813 0.187 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.812 0.188 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.809 0.191 0.000
S06 Intracranial injury
0.807 0.193 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.806 0.194 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.805 0.195 0.000
S60 Superficial injury of wrist and hand
0.805 0.195 0.000
S50 Superficial injury of forearm
0.804 0.196 0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)
0.804 0.196 0.000
E87.3 Alkalosis
0.804 0.196 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.802 0.198 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.801 0.199 0.000
M06 Other rheumatoid arthritis
0.796 0.204 0.000
Chapter XXII Codes for special purposes
0.796 0.204 0.000
Y57 Other and unspecified drugs and medicaments
0.794 0.206 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.792 0.208 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.792 0.208 0.000
G40 Epilepsy
0.791 0.209 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.789 0.211 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.788 0.212 0.000
S51.0 Open wound of elbow
0.788 0.212 0.000
Chapter VIII Diseases of the ear and mastoid process
0.787 0.213 0.000
M00-M03 Infectious arthropathies
0.786 0.214 0.000
E85.4 Organ-limited amyloidosis
0.784 0.216 0.000
G41 Status epilepticus
0.783 0.217 0.000
T66-T78 Other and unspecified effects of external causes
0.783 0.217 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.782 0.218 0.000
V40-V49 Car occupant injured in transport accident
0.782 0.218 0.000
T63 Toxic effect of contact with venomous animals
0.781 0.219 0.000
T91 Sequelae of injuries of neck and trunk
0.778 0.222 0.000
E28 Ovarian dysfunction
0.778 0.222 0.000
E73 Lactose intolerance
0.777 0.223 0.000
M21 Other acquired deformities of limbs
0.776 0.224 0.000
E53 Deficiency of other B group vitamins
0.773 0.227 0.000
S27.2 Traumatic heamopneumothorax
0.772 0.228 0.000
G44 Other headache syndromes
0.772 0.228 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.770 0.230 0.000
M24.02 Loose body in joint (Upper arm)
0.769 0.231 0.000
W20-W49 Exposure to inanimate mechanical forces
0.769 0.231 0.000
E65-E68 Obesity and other hyperalimentation
0.768 0.232 0.000
E22 Hyperfunction of pituitary gland
0.767 0.233 0.000
S64 Injury of nerves at wrist and hand level
0.766 0.234 0.000
T90 Sequelae of injuries of head
0.766 0.234 0.000
E27.2 Addisonian crisis
0.765 0.235 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.765 0.235 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.764 0.236 0.000
S70-S79 Injuries to the hip and thigh
0.764 0.236 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.761 0.239 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.760 0.240 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.760 0.240 0.000
G90-G99 Other disorders of the nervous system
0.759 0.241 0.000
X50-X57 Overexertion, travel and privation
0.756 0.244 0.000
M24.5 Contracture of joint
0.755 0.245 0.000
M33 Dermatopolymyositis
0.755 0.245 0.000
E27.1 Primary adrenocortical insufficiency
0.753 0.247 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.752 0.248 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.750 0.250 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.748 0.252 0.000
M24.2 Disorder of ligament
0.747 0.253 0.000
W50-W64 Exposure to animate mechanical forces
0.747 0.253 0.000
M23.5 Chronic instability of knee
0.744 0.256 0.000
X60-X84 Intentional self-harm
0.743 0.257 0.000
S40-S49 Injuries to the shoulder and upper arm
0.742 0.258 0.000
M23.4 Loose body in knee
0.741 0.258 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.741 0.259 0.000
A04 Other bacterial intestinal infections
0.741 0.259 0.000
M60-M63 Disorders of muscles
0.740 0.260 0.000
Q51 Congenital malformations of uterus and cervix
0.740 0.260 0.000
M34 Systemic sclerosis
0.739 0.261 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.738 0.262 0.000
S32.5 Fracture of pubis
0.737 0.263 0.000
S59 Other and unspecified injuries of forearm
0.736 0.264 0.000
V80-V89 Other land transport accidents
0.735 0.265 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.735 0.265 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.734 0.265 0.000
T51.0 Ethanol
0.733 0.267 0.000
M77 Other enthesopathies
0.732 0.268 0.000
G40.9 Epilepsy, unspecified
0.732 0.268 0.000
M71 Other bursopathies
0.731 0.269 0.000
S56 Injury of muscle and tendon at forearm level
0.731 0.269 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.730 0.270 0.000
G12 Spinal muscular atrophy and related syndromes
0.730 0.270 0.000
B65-B83 Helminthiases
0.728 0.272 0.000
B50-B64 Protozoal diseases
0.727 0.273 0.000
S27.1 Traumatic haemothorax
0.726 0.274 0.000
E85.9 Amyloidosis, unspecified
0.725 0.275 0.000
M06.9 Rheumatoid arthritis, unspecified
0.725 0.275 0.000
A80-A89 Viral infections of the central nervous system
0.725 0.275 0.000
Y43.3 Other antineoplastic drugs
0.725 0.275 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.724 0.276 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.721 0.279 0.000
M76 Enthesopathies of lower limb, excluding foot
0.720 0.280 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.720 0.280 0.000
G41.9 Status epilepticus, unspecified
0.720 0.280 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.719 0.281 0.000
S02 Fracture of skull and facial bones
0.719 0.281 0.000
E53.8 Deficiency of other specified B group vitamins
0.718 0.282 0.000
T51.9 Alcohol, unspecified
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.716 0.284 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.715 0.285 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.285 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.715 0.285 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.715 0.285 0.000
T36 Poisoning by systemic antibiotics
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.285 0.000
Y10-Y34 Event of undetermined intent
0.714 0.285 0.000
Y00-Y09 Assault
0.714 0.285 0.000
X85-X99 Assault
0.714 0.285 0.000
X30-X39 Exposure to forces of nature
0.714 0.285 0.000
X10-X19 Contact with heat and hot substances
0.714 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.285 0.000
W75-W84 Other accidental threats to breathing
0.714 0.285 0.000
W65-W74 Accidental drowning and submersion
0.714 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.285 0.000
V95-V97 Air and space transport accidents
0.714 0.285 0.000
V90-V94 Water transport accidents
0.714 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.285 0.000
T98 Sequelae of other and unspecified effects of external causes
0.714 0.286 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.713 0.287 0.000
S27.3 Other injuries of lung
0.712 0.287 0.000
S32.4 Fracture of acetabulum
0.712 0.288 0.000
E87.4 Mixed disorder of acid-base balance
0.711 0.288 0.000
Y59 Other and unspecified vaccines and biological substances
0.711 0.288 0.000
Y58 Bacterial vaccines
0.711 0.288 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.711 0.288 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.288 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.711 0.288 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.711 0.288 0.000
Y48 Anaesthetics and therapeutic gases
0.711 0.288 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.711 0.288 0.000
E84 Cystic fibrosis
0.711 0.289 0.000
E79 Disorders of purine and pyrimidine metabolism
0.711 0.289 0.000
E77 Disorders of glycoprotein metabolism
0.711 0.289 0.000
E76 Disorders of glycosaminoglycan metabolism
0.711 0.289 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.711 0.289 0.000
E72 Other disorders of amino-acid metabolism
0.711 0.289 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.711 0.289 0.000
E70 Disorders of aromatic amino-acid metabolism
0.711 0.289 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.711 0.289 0.000
Y44 Agents primarily affecting blood constituents
0.711 0.289 0.000
B18 Chronic viral hepatitis
0.711 0.289 0.000
S22.5 Flail chest
0.711 0.289 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.710 0.290 0.000
M32 Systemic lupus erythematosus
0.710 0.290 0.000
M30 Polyarteritis nodosa and related conditions
0.710 0.290 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.709 0.291 0.000
T39.4 Antirheumatics, not elsewhere classified
0.709 0.291 0.000
T39.2 Pyrazolone derivatives
0.709 0.291 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.709 0.291 0.000
T13 Other injuries of lower limb, level unspecified
0.709 0.291 0.000
G44.2 Tension-type headache
0.708 0.292 0.000
E74 Other disorders of carbohydrate metabolism
0.708 0.292 0.000
M86-M90 Other osteopathies
0.708 0.292 0.000
M67 Other disorders of synovium and tendon
0.707 0.293 0.000
S58 Traumatic amputation of forearm
0.707 0.293 0.000
S57 Crushing injury of forearm
0.707 0.293 0.000
S55 Injury of blood vessels at forearm level
0.707 0.293 0.000
S54 Injury of nerves at forearm level
0.707 0.293 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.707 0.293 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.706 0.294 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.706 0.294 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.706 0.294 0.000
A75-A79 Rickettsioses
0.706 0.294 0.000
A70-A74 Other diseases caused by chlamydiae
0.706 0.294 0.000
A65-A69 Other spirochaetal diseases
0.706 0.294 0.000
A20-A28 Certain zoonotic bacterial diseases
0.706 0.294 0.000
A15-A19 Tuberculosis
0.706 0.294 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.706 0.294 0.000
B15 Acute hepatitis A
0.705 0.295 0.000
S52.6 Fracture of lower end of both ulna and radius
0.703 0.297 0.000
X23 Contact with hornets, wasps and bees
0.703 0.297 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.701 0.299 0.000
S20 Superficial injury of thorax
0.701 0.299 0.000
T79.5 Traumatic anuria
0.700 0.300 0.000
S60.8 Other superficial injuries of wrist and hand
0.698 0.302 0.000
Q54 Hypospadias
0.698 0.302 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.698 0.302 0.000
T92 Sequelae of injuries of upper limb
0.697 0.303 0.000
Y42.9 Other and unspecified hormone antagonists
0.697 0.303 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.697 0.303 0.000
Y42.4 Oral contraceptives
0.697 0.303 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.697 0.303 0.000
Y42.2 Antithyroid drugs
0.697 0.303 0.000
Y42.1 Thyroid hormones and substitutes
0.697 0.303 0.000
T43.9 Psychotropic drug, unspecified
0.696 0.304 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.696 0.304 0.000
T43.6 Psychostimulants with abuse potential
0.696 0.304 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.696 0.304 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.696 0.304 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.696 0.304 0.000
T65 Toxic effect of other and unspecified substances
0.696 0.304 0.000
T62 Toxic effect of other noxious substances eaten as food
0.696 0.304 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.696 0.304 0.000
T60 Toxic effect of pesticides
0.696 0.304 0.000
T57 Toxic effect of other inorganic substances
0.696 0.304 0.000
T56 Toxic effect of metals
0.696 0.304 0.000
T54 Toxic effect of corrosive substances
0.696 0.304 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.696 0.304 0.000
T52 Toxic effect of organic solvents
0.696 0.304 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.696 0.304 0.000
T55 Toxic effect of soaps and detergents
0.696 0.304 0.000
Q80-Q89 Other congenital malformations
0.695 0.305 0.000
Y40 Systemic antibiotics
0.695 0.305 0.000
Y52.1 Calcium-channel blockers
0.694 0.305 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.694 0.306 0.000
Y42.5 Other oestrogens and progestogens
0.693 0.307 0.000
M91-M94 Chondropathies
0.692 0.308 0.000
T59 Toxic effect of other gases, fumes and vapours
0.692 0.308 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.691 0.309 0.000
S26 Injury of heart
0.691 0.309 0.000
S25 Injury of blood vessels of thorax
0.691 0.309 0.000
S24 Injury of nerves and spinal cord at thorax level
0.691 0.309 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.691 0.309 0.000
S21 Open wound of thorax
0.691 0.309 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.690 0.310 0.000
S08 Traumatic amputation of part of head
0.690 0.310 0.000
S07 Crushing injury of head
0.690 0.310 0.000
S04 Injury of cranial nerves
0.690 0.310 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.690 0.310 0.000
T79.7 Traumatic subcutaneous emphysema
0.689 0.311 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.688 0.312 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.688 0.312 0.000
E26 Hyperaldosteronism
0.686 0.314 0.000
B16 Acute hepatitis B
0.686 0.314 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.685 0.315 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.685 0.315 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.685 0.315 0.000
M65 Synovitis and tenosynovitis
0.685 0.315 0.000
M23.9 Internal derangement of knee, unspecified
0.684 0.316 0.000
M23.1 Discoid meniscus (congenital)
0.684 0.316 0.000
M23.0 Cystic meniscus
0.684 0.316 0.000
S64.4 Injury of digital nerve of other finger
0.684 0.316 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.684 0.316 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.684 0.316 0.000
S05.1 Contusion of eyeball and orbital tissues
0.683 0.317 0.000
S36 Injury of intra-abdominal organs
0.683 0.317 0.000
E40-E46 Malnutrition
0.682 0.318 0.000
S50.0 Contusion of elbow
0.682 0.318 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.682 0.318 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.681 0.319 0.000
E34 Other endocrine disorders
0.681 0.319 0.000
E32 Diseases of thymus
0.681 0.319 0.000
E31 Polyglandular dysfunction
0.681 0.319 0.000
E30 Disorders of puberty, not elsewhere classified
0.681 0.319 0.000
E25 Adrenogenital disorders
0.681 0.319 0.000
E20 Hypoparathyroidism
0.681 0.319 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.680 0.320 0.000
S51.7 Multiple open wounds of forearm
0.680 0.320 0.000
S05.8 Other injuries of eye and orbit
0.680 0.320 0.000
H65-H75 Diseases of middle ear and mastoid
0.679 0.321 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.679 0.321 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.678 0.321 0.000
X47 Accidental poisoning by and exposure to other gases and vapours
0.678 0.322 0.000
M20 Acquired deformities of fingers and toes
0.677 0.323 0.000
M40-M43 Deforming dorsopathies
0.677 0.323 0.000
S00.7 Multiple superficial injuries of head
0.677 0.323 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.676 0.324 0.000
S52.4 Fracture of shafts of both ulna and radius
0.676 0.324 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.676 0.324 0.000
M23.37 Other meniscus derangements-Capsular lig
0.676 0.324 0.000
A30-A49 Other bacterial diseases
0.676 0.324 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.675 0.325 0.000
G96 Other disorders of central nervous system
0.674 0.326 0.000
S51.8 Open wound of other parts of forearm
0.673 0.327 0.000
S60.2 Contusion of other parts of wrist and hand
0.672 0.328 0.000
B99-B99 Other infectious diseases
0.671 0.329 0.000
S65 Injury of blood vessels at wrist and hand level
0.671 0.329 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.671 0.329 0.000
G12.2 Motor neuron disease
0.671 0.329 0.000
T93 Sequelae of injuries of lower limb
0.671 0.329 0.000
M80-M85 Disorders of bone density and structure
0.670 0.330 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.670 0.330 0.000
S32.50 Fracture of pubis (closed)
0.670 0.330 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.670 0.330 0.000
E65 Localised adiposity
0.669 0.331 0.000
S00.5 Superficial injury of lip and oral cavity
0.669 0.331 0.000
S00.4 Superficial injury of ear
0.669 0.331 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.665 0.335 0.000
S27.9 Injury of unspecified intrathoracic organ
0.665 0.335 0.000
S27.8 Injury of other specified intrathoracic organs
0.665 0.335 0.000
S27.7 Multiple injuries of intrathoracic organs
0.665 0.335 0.000
S27.6 Injury of pleura
0.665 0.335 0.000
S27.5 Injury of thoracic trachea
0.665 0.335 0.000
S27.4 Injury of bronchus
0.665 0.335 0.000
M77.1 Lateral epicondylitis
0.665 0.335 0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents
0.664 0.336 0.000
B25-B34 Other viral diseases
0.661 0.339 0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)
0.661 0.339 0.000
T95 Sequelae of burns, corrosions and frostbite
0.661 0.339 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.661 0.339 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.661 0.339 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.661 0.339 0.000
S30.0 Contusion of lower back and pelvis
0.661 0.339 0.000
M22.1 Recurrent subluxation of patella
0.660 0.339 0.000
M22.9 Disorder of patella, unspecified
0.660 0.339 0.000
M22.0 Recurrent dislocation of patella
0.660 0.339 0.000
S92 Fracture of foot, except ankle
0.660 0.340 0.000
S06.9 Intracranial injury, unspecified
0.660 0.340 0.000
S22.3 Fracture of rib
0.660 0.340 0.000
M31 Other necrotising vasculopathies
0.659 0.340 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.659 0.341 0.000
S37 Injury of urinary and pelvic organs
0.659 0.341 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.659 0.341 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.659 0.341 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.659 0.341 0.000
S31 Open wound of abdomen, lower back and pelvis
0.659 0.341 0.000
X45 Accidental poisoning by and exposure to alcohol
0.659 0.341 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.659 0.341 0.000
Q51.3 Bicornate uterus
0.658 0.342 0.000
S22.4 Multiple fractures of ribs
0.658 0.342 0.000
E27.8 Other specified disorders of adrenal gland
0.657 0.343 0.000
E27.9 Disorder of adrenal gland, unspecified
0.657 0.343 0.000
E27.5 Adrenomedullary hyperfunction
0.657 0.343 0.000
E27.0 Other adrenocortical overactivity
0.657 0.343 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.655 0.345 0.000
S52.2 Fracture of shaft of ulna
0.655 0.345 0.000
M22.8 Other disorders of patella
0.655 0.345 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.655 0.345 0.000
Q35-Q37 Cleft lip and cleft palate
0.655 0.345 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.655 0.345 0.000
E87.2 Acidosis
0.655 0.345 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.654 0.346 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.654 0.346 0.000
Y52.7 Peripheral vasodilators
0.654 0.346 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.654 0.346 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.654 0.346 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.654 0.346 0.000
M24.9 Joint derangement, unspecified
0.653 0.347 0.000
M24.7 Protrusio acetabuli
0.653 0.347 0.000
M24.6 Ankylosis of joint
0.653 0.347 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.653 0.347 0.000
E24 Cushing's syndrome
0.653 0.347 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.653 0.347 0.000
Y57.9 Drug or medicament, unspecified
0.652 0.348 0.000
X49.9 Unspecified place
0.652 0.348 0.000
S70 Superficial injury of hip and thigh
0.651 0.349 0.000
Q00-Q07 Congenital malformations of the nervous system
0.651 0.349 0.000
T90.8 Sequelae of other specified injuries of head
0.651 0.349 0.000
M12 Other specific arthropathies
0.651 0.349 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.651 0.349 0.000
M08 Juvenile arthritis
0.651 0.349 0.000
E86 Volume depletion
0.651 0.349 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.650 0.350 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.648 0.352 0.000
M22.3 Other derangements of patella
0.647 0.353 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.646 0.354 0.000
T63.4 Venom of other arthropods
0.645 0.355 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.645 0.355 0.000
Q60-Q64 Congenital malformations of the urinary system
0.645 0.355 0.000
Chapter X Diseases of the respiratory system
0.645 0.355 0.000
S10 Superficial injury of neck
0.644 0.356 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.644 0.356 0.000
M24.57 Contracture of joint (Ankle and foot)
0.644 0.356 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.644 0.356 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.642 0.357 0.000
E55 Vitamin D deficiency
0.642 0.358 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.641 0.358 0.000
S52.3 Fracture of shaft of radius
0.641 0.359 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.640 0.360 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.640 0.360 0.000
E85.8 Other amyloidosis
0.640 0.360 0.000
E85.3 Secondary systemic amyloidosis
0.640 0.360 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.640 0.360 0.000
E85.1 Neuropathic heredofamilial amyloidosis
0.640 0.360 0.000
E85.0 Nonneuropathic heredofamilial amyloidosis
0.640 0.360 0.000
V10-V19 Pedal cyclist injured in transport accident
0.639 0.361 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.639 0.361 0.000
Q43 Other congenital malformations of intestine
0.639 0.361 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.638 0.362 0.000
E23 Hypofunction and other disorders of pituitary gland
0.638 0.362 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.635 0.365 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.635 0.365 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.635 0.365 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.635 0.365 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.635 0.365 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.635 0.365 0.000
M00 Pyogenic arthritis
0.635 0.365 0.000
M14 Arthropathies in other diseases classified elsewhere
0.634 0.366 0.000
X48 Accidental poisoning by and exposure to pesticides
0.633 0.367 0.000
X46 Accidental poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.633 0.367 0.000
X44 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.633 0.367 0.000
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system
0.633 0.367 0.000
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.633 0.367 0.000
X40 Accidental poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.633 0.367 0.000
T90.4 Sequelae of injury of eye and orbit
0.632 0.368 0.000
M75.9 Shoulder lesion, unspecified
0.632 0.368 0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.629 0.371 0.000
S32.40 Fracture of acetabulum (closed)
0.628 0.372 0.000
S32.1 Fracture of sacrum
0.628 0.372 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.628 0.372 0.000
M06.4 Inflammatory polyarthropathy
0.626 0.374 0.000
S52.1 Fracture of upper end of radius
0.626 0.374 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.625 0.375 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.625 0.375 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.625 0.375 0.000
S22.50 Flail chest (closed)
0.624 0.376 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.623 0.377 0.000
E73.9 Lactose intolerance, unspecified
0.622 0.378 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.622 0.378 0.000
G47 Sleep disorders
0.622 0.378 0.000
M35 Other systemic involvement of connective tissue
0.622 0.378 0.000
T13.0 Superficial injury of lower limb, level unspecified
0.621 0.379 0.000
V20-V29 Motorcycle rider injured in transport accident
0.621 0.379 0.000
M05.8 Other seropositive rheumatoid arthritis
0.620 0.380 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.620 0.380 0.000
M05.2 Rheumatoid vasculitis
0.620 0.380 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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