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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78895459
log Bayes Factor = 11.7915
Chromosome 7   position 53,781,545  (GRCh37) Explore rs78895459 on Ensembl!
Variant rs78895459 is part of Cluster X0020

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.996 0.004 0.000
Chapter X Diseases of the respiratory system
0.995 0.005 0.000
M05-M14 Inflammatory polyarthropathies
0.994 0.006 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.992 0.008 0.000
E10-E14 Diabetes mellitus
0.988 0.012 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.983 0.017 0.000
J09-J18 Influenza and pneumonia
0.982 0.018 0.000
Chapter IX Diseases of the circulatory system
0.980 0.020 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.980 0.020 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.979 0.021 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.972 0.028 0.000
E10 Insulin-dependent diabetes mellitus
0.971 0.029 0.000
I73 Other peripheral vascular diseases
0.968 0.032 0.000
M50-M54 Other dorsopathies
0.964 0.036 0.000
E70-E90 Metabolic disorders
0.964 0.036 0.000
I73.9 Peripheral vascular disease, unspecified
0.962 0.038 0.000
Chapter XIV Diseases of the genitourinary system
0.957 0.043 0.000
I60-I69 Cerebrovascular diseases
0.953 0.047 0.000
M13 Other arthritis
0.951 0.049 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.945 0.055 0.000
Chapter VI Diseases of the nervous system
0.944 0.056 0.000
N20-N23 Urolithiasis
0.940 0.060 0.000
S00-S09 Injuries to the head
0.939 0.061 0.000
S40-S49 Injuries to the shoulder and upper arm
0.939 0.061 0.000
Chapter I Certain infectious and parasitic diseases
0.937 0.063 0.000
M54 Dorsalgia
0.933 0.067 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.933 0.067 0.000
M10 Gout
0.928 0.072 0.000
J40-J47 Chronic lower respiratory diseases
0.927 0.073 0.000
N20 Calculus of kidney and ureter
0.926 0.074 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.923 0.077 0.000
M06 Other rheumatoid arthritis
0.922 0.078 0.000
N10-N16 Renal tubulo-interstitial diseases
0.921 0.079 0.000
J18 Pneumonia, organism unspecified
0.920 0.080 0.000
J44 Other chronic obstructive pulmonary disease
0.919 0.081 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.914 0.086 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.913 0.087 0.000
N13 Obstructive and reflux uropathy
0.908 0.092 0.000
N20.0 Calculus of kidney
0.905 0.095 0.000
E10.9 Without complications
0.902 0.098 0.000
J18.1 Lobar pneumonia, unspecified
0.900 0.100 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.899 0.101 0.000
I60 Subarachnoid haemorrhage
0.899 0.101 0.000
M13.9 Arthritis, unspecified
0.898 0.102 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.897 0.103 0.000
N13.3 Other and unspecified hydronephrosis
0.896 0.104 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.889 0.111 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.888 0.112 0.000
I61 Intracerebral haemorrhage
0.888 0.112 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.886 0.114 0.000
I74 Arterial embolism and thrombosis
0.885 0.115 0.000
S80-S89 Injuries to the knee and lower leg
0.885 0.115 0.000
E83 Disorders of mineral metabolism
0.884 0.116 0.000
G90-G99 Other disorders of the nervous system
0.882 0.118 0.000
M10.9 Gout, unspecified
0.881 0.119 0.000
T81 Complications of procedures, not elsewhere classified
0.879 0.121 0.000
C77.0 Lymph nodes of head, face and neck
0.879 0.121 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.876 0.124 0.000
C77.3 Axillary and upper limb lymph nodes
0.875 0.125 0.000
I77 Other disorders of arteries and arterioles
0.874 0.126 0.000
O80-O84 Delivery
0.868 0.132 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.868 0.132 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.867 0.133 0.000
M06.9 Rheumatoid arthritis, unspecified
0.866 0.134 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.865 0.135 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.861 0.139 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.860 0.140 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.860 0.140 0.000
D00-D09 In situ neoplasms
0.859 0.141 0.000
E11 Non-insulin-dependent diabetes mellitus
0.856 0.144 0.000
J90-J94 Other diseases of pleura
0.856 0.144 0.000
C15-C26 Malignant neoplasms of digestive organs
0.856 0.144 0.000
M54.9 Dorsalgia, unspecified
0.854 0.146 0.000
E10.4 With neurological complications
0.853 0.147 0.000
M54.5 Low back pain
0.853 0.147 0.000
D50-D53 Nutritional anaemias
0.851 0.149 0.000
J00-J06 Acute upper respiratory infections
0.849 0.151 0.000
E10.3 With ophthalmic complications
0.848 0.152 0.000
Chapter VIII Diseases of the ear and mastoid process
0.847 0.153 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.845 0.155 0.000
C77.2 Intra-abdominal lymph nodes
0.844 0.156 0.000
M50 Cervical disk disorders
0.844 0.156 0.000
M05 Seropositive rheumatoid arthritis
0.835 0.165 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.835 0.165 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.830 0.170 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.830 0.170 0.000
E65-E68 Obesity and other hyperalimentation
0.829 0.171 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.828 0.172 0.000
Chapter XXII Codes for special purposes
0.827 0.173 0.000
S01 Open wound of head
0.826 0.174 0.000
M10.99 Gout, unspecified (Site unspecified)
0.825 0.175 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.823 0.177 0.000
E88 Other metabolic disorders
0.820 0.180 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.817 0.183 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.815 0.185 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.814 0.186 0.000
C79 Secondary malignant neoplasm of other sites
0.812 0.188 0.000
S82 Fracture of lower leg, including ankle
0.811 0.189 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.810 0.190 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.809 0.191 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.806 0.194 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.805 0.195 0.000
S70-S79 Injuries to the hip and thigh
0.804 0.196 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.802 0.198 0.000
C64-C68 Malignant neoplasms of urinary tract
0.801 0.199 0.000
D04 Carcinoma in situ of skin
0.800 0.200 0.000
N20.1 Calculus of ureter
0.799 0.201 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.796 0.204 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.796 0.204 0.000
M13.0 Polyarthritis, unspecified
0.795 0.205 0.000
E87.5 Hyperkalaemia
0.794 0.206 0.000
C44 Other malignant neoplasms of skin
0.791 0.209 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.790 0.210 0.000
B95-B98 Bacterial, viral and other infectious agents
0.790 0.210 0.000
Chapter XX External causes of morbidity and mortality
0.790 0.210 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.790 0.210 0.000
D73 Diseases of spleen
0.790 0.210 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.789 0.211 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.787 0.213 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.787 0.213 0.000
E87.2 Acidosis
0.786 0.214 0.000
T79-T79 Certain early complications of trauma
0.786 0.214 0.000
M54.57 Low back pain (Lumbosacral region)
0.786 0.214 0.000
G30-G32 Other degenerative diseases of the nervous system
0.784 0.216 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.783 0.217 0.000
I71 Aortic aneurysm and dissection
0.783 0.217 0.000
E10.5 With peripheral circulatory complications
0.781 0.219 0.000
E50-E64 Other nutritional deficiencies
0.778 0.222 0.000
E20-E35 Disorders of other endocrine glands
0.777 0.223 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.777 0.223 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.776 0.224 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.776 0.224 0.000
C77.9 Lymph node, unspecified
0.775 0.225 0.000
H60-H62 Diseases of external ear
0.775 0.225 0.000
J02 Acute pharyngitis
0.774 0.226 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.773 0.227 0.000
S42 Fracture of shoulder and upper arm
0.773 0.227 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.771 0.228 0.000
D50 Iron deficiency anaemia
0.770 0.230 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.770 0.230 0.000
S02 Fracture of skull and facial bones
0.769 0.231 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.768 0.232 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.767 0.233 0.000
I62 Other nontraumatic intracranial haemorrhage
0.766 0.234 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.765 0.235 0.000
C78.0 Secondary malignant neoplasm of lung
0.765 0.235 0.000
M91-M94 Chondropathies
0.764 0.236 0.000
M54.4 Lumbago with sciatica
0.763 0.237 0.000
O80 Single spontaneous delivery
0.762 0.238 0.000
J90 Pleural effusion, not elsewhere classified
0.761 0.239 0.000
C45 Mesothelioma
0.760 0.240 0.000
B02 Zoster [herpes zoster]
0.760 0.240 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.759 0.241 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.759 0.241 0.000
N99-N99 Other disorders of the genitourinary system
0.759 0.241 0.000
S50-S59 Injuries to the elbow and forearm
0.758 0.242 0.000
D72 Other disorders of white blood cells
0.758 0.242 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.758 0.242 0.000
J10 Influenza due to identified influenza virus
0.757 0.242 0.000
S80 Superficial injury of lower leg
0.757 0.243 0.000
M80-M85 Disorders of bone density and structure
0.756 0.244 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.756 0.244 0.000
O24 Diabetes mellitus in pregnancy
0.756 0.244 0.000
E11.6 With other specified complications
0.754 0.246 0.000
D45 Polycythaemia vera
0.752 0.248 0.000
N30-N39 Other diseases of urinary system
0.752 0.248 0.000
S05 Injury of eye and orbit
0.751 0.249 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.749 0.251 0.000
S06 Intracranial injury
0.748 0.252 0.000
C01 Malignant neoplasm of base of tongue
0.748 0.252 0.000
C77.8 Lymph nodes of multiple regions
0.748 0.252 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.747 0.253 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.746 0.254 0.000
S40 Superficial injury of shoulder and upper arm
0.745 0.254 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.745 0.255 0.000
G93 Other disorders of brain
0.743 0.257 0.000
M07 Psoriatic and enteropathic arthropathies
0.742 0.258 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.741 0.259 0.000
I77.1 Stricture of artery
0.741 0.259 0.000
E11.5 With peripheral circulatory complications
0.740 0.260 0.000
I74.5 Embolism and thrombosis of iliac artery
0.739 0.260 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.739 0.261 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.739 0.261 0.000
G70-G73 Diseases of myoneural junction and muscle
0.738 0.262 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.738 0.262 0.000
S09 Other and unspecified injuries of head
0.737 0.263 0.000
E13 Other specified diabetes mellitus
0.737 0.263 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.737 0.263 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.737 0.263 0.000
S01.1 Open wound of eyelid and periocular area
0.737 0.263 0.000
E65 Localised adiposity
0.736 0.264 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.736 0.264 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.735 0.264 0.000
B15-B19 Viral hepatitis
0.735 0.265 0.000
O26.9 Pregnancy-related condition, unspecified
0.735 0.265 0.000
N72 Inflammatory disease of cervix uteri
0.735 0.265 0.000
D73.0 Hyposplenism
0.734 0.266 0.000
C44.2 Skin of ear and external auricular canal
0.733 0.267 0.000
E83.4 Disorders of magnesium metabolism
0.733 0.267 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.732 0.268 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.732 0.268 0.000
I72 Other aneurysm
0.732 0.268 0.000
S10-S19 Injuries to the neck
0.731 0.269 0.000
M45-M49 Spondylopathies
0.730 0.270 0.000
B00 Herpesviral [herpes simplex] infections
0.730 0.270 0.000
D75 Other diseases of blood and blood-forming organs
0.729 0.271 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.729 0.271 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.729 0.271 0.000
N13.4 Hydroureter
0.728 0.272 0.000
N20.9 Urinary calculus, unspecified
0.727 0.272 0.000
N32 Other disorders of bladder
0.726 0.274 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.726 0.274 0.000
N70 Salpingitis and oophoritis
0.724 0.276 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.722 0.278 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.722 0.278 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.722 0.278 0.000
T87 Complications peculiar to reattachment and amputation
0.722 0.278 0.000
T88.4 Failed or difficult intubation
0.721 0.279 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.721 0.279 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.720 0.280 0.000
J02.9 Acute pharyngitis, unspecified
0.720 0.280 0.000
E83.1 Disorders of iron metabolism
0.719 0.280 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.719 0.281 0.000
B35-B49 Mycoses
0.718 0.282 0.000
O41 Other disorders of amniotic fluid and membranes
0.717 0.283 0.000
E87.6 Hypokalaemia
0.717 0.283 0.000
T66-T78 Other and unspecified effects of external causes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
E40-E46 Malnutrition
0.716 0.284 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.715 0.285 0.000
O42 Premature rupture of membranes
0.715 0.285 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.714 0.286 0.000
M60-M63 Disorders of muscles
0.714 0.286 0.000
M00-M03 Infectious arthropathies
0.714 0.286 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.713 0.287 0.000
M14 Arthropathies in other diseases classified elsewhere
0.713 0.287 0.000
M12 Other specific arthropathies
0.713 0.287 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.713 0.287 0.000
M08 Juvenile arthritis
0.713 0.287 0.000
E88.2 Lipomatosis, not elsewhere classified
0.712 0.288 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.711 0.289 0.000
S01.4 Open wound of cheek and temporomandibular area
0.711 0.289 0.000
I61.8 Other intracerebral haemorrhage
0.710 0.290 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.710 0.290 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.708 0.292 0.000
E12 Malnutrition-related diabetes mellitus
0.708 0.292 0.000
O36 Maternal care for other known or suspected foetal problems
0.708 0.292 0.000
E83.3 Disorders of phosphorus metabolism
0.707 0.293 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.707 0.293 0.000
H65-H75 Diseases of middle ear and mastoid
0.707 0.293 0.000
D50.8 Other iron deficiency anaemias
0.706 0.294 0.000
J84 Other interstitial pulmonary diseases
0.706 0.294 0.000
M50.0 Cervical disk disorder with myelopathy
0.706 0.294 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.705 0.295 0.000
H61 Other disorders of external ear
0.705 0.295 0.000
O85-O92 Complications predominantly related to the puerperium
0.704 0.295 0.000
M06.4 Inflammatory polyarthropathy
0.704 0.296 0.000
J17 Pneumonia in diseases classified elsewhere
0.704 0.296 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.704 0.296 0.000
J12 Viral pneumonia, not elsewhere classified
0.704 0.296 0.000
J14 Pneumonia due to Haemophilus influenzae
0.704 0.296 0.000
J09 Influenza due to certain identified influenza virus
0.704 0.296 0.000
G91 Hydrocephalus
0.704 0.296 0.000
I00-I02 Acute rheumatic fever
0.703 0.297 0.000
C91 Lymphoid leukaemia
0.703 0.297 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.702 0.298 0.000
I78 Diseases of capillaries
0.702 0.298 0.000
C60-C63 Malignant neoplasms of male genital organs
0.702 0.298 0.000
Y83.8 Other surgical procedures
0.701 0.299 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.700 0.300 0.000
C77.4 Inguinal and lower limb lymph nodes
0.700 0.300 0.000
C80 Malignant neoplasm without specification of site
0.699 0.301 0.000
N21 Calculus of lower urinary tract
0.699 0.301 0.000
C77.5 Intrapelvic lymph nodes
0.698 0.302 0.000
N23 Unspecified renal colic
0.698 0.302 0.000
N13.6 Pyonephrosis
0.698 0.302 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.698 0.302 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.698 0.302 0.000
G40-G47 Episodic and paroxysmal disorders
0.698 0.302 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.698 0.302 0.000
M54.59 Low back pain (Site unspecified)
0.697 0.303 0.000
E10.8 With unspecified complications
0.696 0.304 0.000
E10.7 With multiple complications
0.696 0.304 0.000
E10.6 With other specified complications
0.696 0.304 0.000
E10.2 With renal complications
0.696 0.304 0.000
E10.0 With coma
0.696 0.304 0.000
T81.9 Unspecified complication of procedure
0.696 0.304 0.000
N73 Other female pelvic inflammatory diseases
0.696 0.304 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.695 0.305 0.000
C18 Malignant neoplasm of colon
0.695 0.305 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.694 0.306 0.000
I73.8 Other specified peripheral vascular diseases
0.694 0.306 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.694 0.306 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.692 0.308 0.000
M53 Other dorsopathies, not elsewhere classified
0.691 0.308 0.000
E85 Amyloidosis
0.691 0.309 0.000
E84 Cystic fibrosis
0.691 0.309 0.000
E79 Disorders of purine and pyrimidine metabolism
0.691 0.309 0.000
E77 Disorders of glycoprotein metabolism
0.691 0.309 0.000
E76 Disorders of glycosaminoglycan metabolism
0.691 0.309 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.691 0.309 0.000
E74 Other disorders of carbohydrate metabolism
0.691 0.309 0.000
E73 Lactose intolerance
0.691 0.309 0.000
E72 Other disorders of amino-acid metabolism
0.691 0.309 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.691 0.309 0.000
E70 Disorders of aromatic amino-acid metabolism
0.691 0.309 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.691 0.309 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.691 0.309 0.000
S82.2 Fracture of shaft of tibia
0.691 0.309 0.000
D04.7 Skin of lower limb, including hip
0.691 0.309 0.000
T86 Failure and rejection of transplanted organs and tissues
0.690 0.310 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.690 0.310 0.000
D04.3 Skin of other and unspecified parts of face
0.688 0.312 0.000
C15 Malignant neoplasm of oesophagus
0.688 0.312 0.000
O80.9 Single spontaneous delivery, unspecified
0.688 0.312 0.000
S90-S99 Injuries to the ankle and foot
0.687 0.313 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.687 0.313 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.686 0.313 0.000
C44.6 Skin of upper limb, including shoulder
0.686 0.314 0.000
M50.2 Other cervical disk displacement
0.686 0.314 0.000
N71 Inflammatory disease of uterus, except cervix
0.686 0.314 0.000
I70 Atherosclerosis
0.685 0.314 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.685 0.315 0.000
J47 Bronchiectasis
0.684 0.316 0.000
M11 Other crystal arthropathies
0.684 0.316 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.683 0.317 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.683 0.317 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.683 0.317 0.000
M13.00 Polyarthritis, unspecified (Multiple sites)
0.683 0.317 0.000
O20 Haemorrhage in early pregnancy
0.683 0.317 0.000
M13.8 Other specified arthritis
0.682 0.318 0.000
M13.1 Monoarthritis, not elsewhere classified
0.682 0.318 0.000
J11 Influenza, virus not identified
0.681 0.319 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.681 0.319 0.000
E83.5 Disorders of calcium metabolism
0.681 0.319 0.000
B01 Varicella [chickenpox]
0.680 0.320 0.000
J46 Status asthmaticus
0.680 0.320 0.000
M10.96 Gout, unspecified (Lower leg)
0.680 0.320 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.680 0.320 0.000
D72.8 Other specified disorders of white blood cells
0.680 0.320 0.000
S43.0 Dislocation of shoulder joint
0.679 0.321 0.000
D55-D59 Haemolytic anaemias
0.678 0.322 0.000
I69 Sequelae of cerebrovascular disease
0.678 0.322 0.000
M86-M90 Other osteopathies
0.677 0.323 0.000
N11 Chronic tubulo-interstitial nephritis
0.677 0.323 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.676 0.324 0.000
S82.8 Fractures of other parts of lower leg
0.676 0.324 0.000
D37.5 Rectum
0.675 0.325 0.000
E14 Unspecified diabetes mellitus
0.675 0.325 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.674 0.326 0.000
S08 Traumatic amputation of part of head
0.673 0.327 0.000
S07 Crushing injury of head
0.673 0.327 0.000
S04 Injury of cranial nerves
0.673 0.327 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.673 0.327 0.000
C02.9 Tongue, unspecified
0.673 0.327 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.673 0.327 0.000
S48 Traumatic amputation of shoulder and upper arm
0.673 0.327 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.673 0.327 0.000
S44 Injury of nerves at shoulder and upper arm level
0.673 0.327 0.000
S41 Open wound of shoulder and upper arm
0.673 0.327 0.000
S47 Crushing injury of shoulder and upper arm
0.673 0.327 0.000
B99-B99 Other infectious diseases
0.672 0.328 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.672 0.328 0.000
B65-B83 Helminthiases
0.672 0.328 0.000
B50-B64 Protozoal diseases
0.672 0.328 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.672 0.328 0.000
A75-A79 Rickettsioses
0.672 0.328 0.000
A70-A74 Other diseases caused by chlamydiae
0.672 0.328 0.000
A65-A69 Other spirochaetal diseases
0.672 0.328 0.000
A20-A28 Certain zoonotic bacterial diseases
0.672 0.328 0.000
A15-A19 Tuberculosis
0.672 0.328 0.000
L20-L30 Dermatitis and eczema
0.671 0.329 0.000
J92 Pleural plaque
0.670 0.330 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.670 0.330 0.000
S42.1 Fracture of scapula
0.670 0.330 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.669 0.331 0.000
M54.8 Other dorsalgia
0.669 0.331 0.000
M54.0 Panniculitis affecting regions of neck and back
0.669 0.331 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.668 0.332 0.000
J18.0 Bronchopneumonia, unspecified
0.667 0.333 0.000
C44.5 Skin of trunk
0.667 0.333 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.665 0.334 0.000
M10.4 Other secondary gout
0.665 0.335 0.000
M10.3 Gout due to impairment of renal function
0.665 0.335 0.000
M10.2 Drug-induced gout
0.665 0.335 0.000
M10.1 Lead-induced gout
0.665 0.335 0.000
M10.0 Idiopathic gout
0.665 0.335 0.000
J41 Simple and mucopurulent chronic bronchitis
0.665 0.335 0.000
A80-A89 Viral infections of the central nervous system
0.664 0.336 0.000
M54.6 Pain in thoracic spine
0.662 0.338 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.662 0.338 0.000
E11.1 With ketoacidosis
0.662 0.338 0.000
M40-M43 Deforming dorsopathies
0.662 0.338 0.000
J60-J70 Lung diseases due to external agents
0.661 0.338 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.661 0.338 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.661 0.338 0.000
M06.8 Other specified rheumatoid arthritis
0.661 0.339 0.000
M06.3 Rheumatoid nodule
0.661 0.339 0.000
M06.2 Rheumatoid bursitis
0.661 0.339 0.000
M06.1 Adult-onset Still's disease
0.661 0.339 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.660 0.339 0.000
N15 Other renal tubulo-interstitial diseases
0.660 0.339 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.660 0.339 0.000
O81 Single delivery by forceps and vacuum extractor
0.660 0.340 0.000
J18.8 Other pneumonia, organism unspecified
0.660 0.340 0.000
J18.2 Hypostatic pneumonia, unspecified
0.660 0.340 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.657 0.343 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.657 0.343 0.000
B25-B34 Other viral diseases
0.657 0.343 0.000
M54.1 Radiculopathy
0.657 0.343 0.000
D06 Carcinoma in situ of cervix uteri
0.657 0.343 0.000
N32.0 Bladder-neck obstruction
0.656 0.344 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.655 0.345 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.655 0.345 0.000
O97 Death from sequelae of direct obstetric causes
0.655 0.345 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.655 0.345 0.000
O95 Obstetric death of unspecified cause
0.655 0.345 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.655 0.345 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.655 0.345 0.000
C09 Malignant neoplasm of tonsil
0.655 0.345 0.000
O29 Complications of anaesthesia during pregnancy
0.655 0.345 0.000
O28 Abnormal findings on antenatal screening of mother
0.655 0.345 0.000
O23 Infections of genito-urinary tract in pregnancy
0.655 0.345 0.000
O22 Venous complications in pregnancy
0.655 0.345 0.000
O21 Excessive vomiting in pregnancy
0.655 0.345 0.000
O25 Malnutrition in pregnancy
0.655 0.345 0.000
O16 Unspecified maternal hypertension
0.655 0.345 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.654 0.346 0.000
M54.2 Cervicalgia
0.654 0.346 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.653 0.346 0.000
C79.2 Secondary malignant neoplasm of skin
0.653 0.347 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.652 0.348 0.000
C45.0 Mesothelioma of pleura
0.651 0.349 0.000
O36.8 Maternal care for other specified foetal problems
0.651 0.349 0.000
J43 Emphysema
0.651 0.349 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.651 0.349 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.651 0.349 0.000
N32.9 Bladder disorder, unspecified
0.650 0.350 0.000
D51 Vitamin B12 deficiency anaemia
0.650 0.350 0.000
N75 Diseases of Bartholin's gland
0.650 0.350 0.000
C91.1 Chronic lymphocytic leukaemia
0.650 0.350 0.000
S82.5 Fracture of medial malleolus
0.650 0.350 0.000
O26.8 Other specified pregnancy-related conditions
0.650 0.350 0.000
D46 Myelodysplastic syndromes
0.648 0.352 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.648 0.352 0.000
D80-D89 Certain disorders involving the immune mechanism
0.648 0.352 0.000
T90 Sequelae of injuries of head
0.647 0.353 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.647 0.353 0.000
S72 Fracture of femur
0.647 0.353 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.646 0.354 0.000
O82 Single delivery by Caesarean section
0.646 0.354 0.000
G96 Other disorders of central nervous system
0.646 0.354 0.000
D75.1 Secondary polycythaemia
0.645 0.355 0.000
S80.8 Other superficial injuries of lower leg
0.645 0.355 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.645 0.355 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.645 0.355 0.000
I60.8 Other subarachnoid haemorrhage
0.644 0.356 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.644 0.356 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.644 0.356 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.644 0.356 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.644 0.356 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.644 0.356 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.644 0.356 0.000
M13.93 Arthritis, unspecified (Forearm)
0.644 0.356 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.644 0.356 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.643 0.357 0.000
C13 Malignant neoplasm of hypopharynx
0.643 0.357 0.000
C11 Malignant neoplasm of nasopharynx
0.643 0.357 0.000
C10 Malignant neoplasm of oropharynx
0.643 0.357 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.643 0.357 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.643 0.357 0.000
C05 Malignant neoplasm of palate
0.643 0.357 0.000
C04 Malignant neoplasm of floor of mouth
0.643 0.357 0.000
C03 Malignant neoplasm of gum
0.643 0.357 0.000
C00 Malignant neoplasm of lip
0.643 0.357 0.000
C12 Malignant neoplasm of pyriform sinus
0.643 0.357 0.000
C07 Malignant neoplasm of parotid gland
0.643 0.357 0.000
E87.0 Hyperosmolality and hypernatraemia
0.643 0.357 0.000
C66 Malignant neoplasm of ureter
0.643 0.357 0.000
M50.1 Cervical disk disorder with radiculopathy
0.642 0.358 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.642 0.358 0.000
D47.1 Chronic myeloproliferative disease
0.641 0.358 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.641 0.359 0.000
S89 Other and unspecified injuries of lower leg
0.641 0.359 0.000
J94 Other pleural conditions
0.640 0.360 0.000
J95-J99 Other diseases of the respiratory system
0.640 0.360 0.000
V20-V29 Motorcycle rider injured in transport accident
0.639 0.361 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.638 0.362 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.638 0.362 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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