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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78897171
log Bayes Factor = 4.02131
Chromosome 20   position 60,443,251  (GRCh37) Explore rs78897171 on Ensembl!
Variant rs78897171 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
D10-D36 Benign neoplasms
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.996 0.004 0.000
Chapter IX Diseases of the circulatory system
0.992 0.008 0.000
I30-I52 Other forms of heart disease
0.989 0.011 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.987 0.013 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.965 0.035 0.000
E00-E07 Disorders of thyroid gland
0.964 0.036 0.000
I51 Complications and ill-defined descriptions of heart disease
0.953 0.047 0.000
D22 Melanocytic naevi
0.950 0.050 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.949 0.051 0.000
E10-E14 Diabetes mellitus
0.924 0.076 0.000
I49 Other cardiac arrhythmias
0.913 0.087 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.912 0.088 0.000
I47 Paroxysmal tachycardia
0.907 0.093 0.000
Chapter VIII Diseases of the ear and mastoid process
0.900 0.100 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.893 0.107 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.893 0.107 0.000
D12.8 Rectum
0.884 0.116 0.000
Chapter XIV Diseases of the genitourinary system
0.883 0.117 0.000
I51.7 Cardiomegaly
0.880 0.120 0.000
E20-E35 Disorders of other endocrine glands
0.877 0.123 0.000
Chapter XX External causes of morbidity and mortality
0.876 0.124 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.872 0.128 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.864 0.136 0.000
I45 Other conduction disorders
0.861 0.139 0.000
D12.0 Caecum
0.853 0.147 0.000
D23 Other benign neoplasms of skin
0.849 0.151 0.000
E70-E90 Metabolic disorders
0.848 0.152 0.000
E06 Thyroiditis
0.846 0.154 0.000
D12.7 Rectosigmoid junction
0.843 0.157 0.000
M70-M79 Other soft tissue disorders
0.843 0.157 0.000
D32 Benign neoplasm of meninges
0.840 0.160 0.000
D12.4 Descending colon
0.837 0.163 0.000
I51.8 Other ill-defined heart diseases
0.836 0.164 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.835 0.165 0.000
D22.5 Melanocytic naevi of trunk
0.831 0.169 0.000
L20-L30 Dermatitis and eczema
0.830 0.170 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.830 0.170 0.000
N40-N51 Diseases of male genital organs
0.826 0.174 0.000
L82 Seborrhoeic keratosis
0.825 0.175 0.000
D12.2 Ascending colon
0.820 0.180 0.000
C44 Other malignant neoplasms of skin
0.820 0.180 0.000
I47.1 Supraventricular tachycardia
0.813 0.187 0.000
I34 Nonrheumatic mitral valve disorders
0.810 0.190 0.000
E14 Unspecified diabetes mellitus
0.810 0.190 0.000
M20-M25 Other joint disorders
0.809 0.191 0.000
E10 Insulin-dependent diabetes mellitus
0.805 0.195 0.000
E05.9 Thyrotoxicosis, unspecified
0.804 0.196 0.000
E03 Other hypothyroidism
0.803 0.197 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.801 0.199 0.000
L50-L54 Urticaria and erythema
0.797 0.203 0.000
I49.9 Cardiac arrhythmia, unspecified
0.794 0.206 0.000
D36 Benign neoplasm of other and unspecified sites
0.791 0.209 0.000
I46 Cardiac arrest
0.784 0.216 0.000
I20-I25 Ischaemic heart diseases
0.779 0.221 0.000
M45-M49 Spondylopathies
0.776 0.224 0.000
N17-N19 Renal failure
0.776 0.224 0.000
D35.2 Pituitary gland
0.773 0.227 0.000
Chapter VI Diseases of the nervous system
0.770 0.230 0.000
H90-H95 Other disorders of ear
0.769 0.231 0.000
M15-M19 Arthrosis
0.768 0.232 0.000
C15-C26 Malignant neoplasms of digestive organs
0.768 0.232 0.000
D34 Benign neoplasm of thyroid gland
0.765 0.234 0.000
Chapter XXII Codes for special purposes
0.763 0.237 0.000
D22.4 Melanocytic naevi of scalp and neck
0.761 0.239 0.000
I49.0 Ventricular fibrillation and flutter
0.761 0.239 0.000
E06.3 Autoimmune thyroiditis
0.761 0.239 0.000
D10 Benign neoplasm of mouth and pharynx
0.761 0.239 0.000
M40-M43 Deforming dorsopathies
0.758 0.242 0.000
N41 Inflammatory diseases of prostate
0.753 0.247 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.751 0.248 0.000
C60-C63 Malignant neoplasms of male genital organs
0.751 0.249 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.751 0.249 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.749 0.251 0.000
I47.2 Ventricular tachycardia
0.748 0.252 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.748 0.252 0.000
H65-H75 Diseases of middle ear and mastoid
0.748 0.252 0.000
N60-N64 Disorders of breast
0.748 0.252 0.000
N00-N08 Glomerular diseases
0.748 0.252 0.000
M19 Other arthrosis
0.747 0.253 0.000
D12.3 Transverse colon
0.745 0.255 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.744 0.256 0.000
L90 Atrophic disorders of skin
0.742 0.257 0.000
D23.5 Skin of trunk
0.737 0.263 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.737 0.263 0.000
M19.9 Arthrosis, unspecified
0.732 0.268 0.000
D27 Benign neoplasm of ovary
0.731 0.269 0.000
I51.9 Heart disease, unspecified
0.731 0.269 0.000
M20 Acquired deformities of fingers and toes
0.728 0.272 0.000
E14.9 Without complications
0.728 0.272 0.000
D32.0 Cerebral meninges
0.727 0.273 0.000
E78.0 Pure hypercholesterolaemia
0.724 0.276 0.000
I05-I09 Chronic rheumatic heart diseases
0.723 0.277 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.722 0.278 0.000
E07 Other disorders of thyroid
0.720 0.280 0.000
I38 Endocarditis, valve unspecified
0.718 0.282 0.000
I45.6 Preexcitation syndrome
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.716 0.284 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.716 0.284 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.716 0.284 0.000
L29 Pruritus
0.716 0.284 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.716 0.284 0.000
D31 Benign neoplasm of eye and adnexa
0.716 0.284 0.000
D30 Benign neoplasm of urinary organs
0.716 0.284 0.000
D29 Benign neoplasm of male genital organs
0.716 0.284 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.716 0.284 0.000
D26 Other benign neoplasms of uterus
0.716 0.284 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.716 0.284 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.716 0.284 0.000
D19 Benign neoplasm of mesothelial tissue
0.716 0.284 0.000
D16 Benign neoplasm of bone and articular cartilage
0.716 0.284 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.716 0.284 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.716 0.284 0.000
D11 Benign neoplasm of major salivary glands
0.716 0.284 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.714 0.285 0.000
E40-E46 Malnutrition
0.714 0.286 0.000
E10.9 Without complications
0.713 0.287 0.000
I49.8 Other specified cardiac arrhythmias
0.712 0.287 0.000
M80-M85 Disorders of bone density and structure
0.712 0.288 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.712 0.288 0.000
I00-I02 Acute rheumatic fever
0.711 0.289 0.000
D12.6 Colon, unspecified
0.709 0.290 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.709 0.291 0.000
I52 Other heart disorders in diseases classified elsewhere
0.709 0.291 0.000
I48 Atrial fibrillation and flutter
0.709 0.291 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.709 0.291 0.000
I41 Myocarditis in diseases classified elsewhere
0.709 0.291 0.000
I40 Acute myocarditis
0.709 0.291 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.709 0.291 0.000
I37 Pulmonary valve disorders
0.709 0.291 0.000
I36 Nonrheumatic tricuspid valve disorders
0.709 0.291 0.000
I33 Acute and subacute endocarditis
0.709 0.291 0.000
I32 Pericarditis in diseases classified elsewhere
0.709 0.291 0.000
I30 Acute pericarditis
0.709 0.291 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.709 0.291 0.000
D12.9 Anus and anal canal
0.708 0.292 0.000
D12.1 Appendix
0.708 0.292 0.000
E83 Disorders of mineral metabolism
0.707 0.293 0.000
I45.1 Other and unspecified right bundle-branch block
0.706 0.294 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.703 0.297 0.000
D35.0 Adrenal gland
0.701 0.299 0.000
I49.4 Other and unspecified premature depolarisation
0.699 0.301 0.000
L81 Other disorders of pigmentation
0.695 0.305 0.000
D23.4 Skin of scalp and neck
0.695 0.305 0.000
E27 Other disorders of adrenal gland
0.695 0.305 0.000
L91 Hypertrophic disorders of skin
0.693 0.307 0.000
L10-L14 Bullous disorders
0.692 0.308 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.692 0.308 0.000
D23.7 Skin of lower limb, including hip
0.691 0.308 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.691 0.309 0.000
E00 Congenital iodine-deficiency syndrome
0.691 0.309 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.691 0.309 0.000
I71 Aortic aneurysm and dissection
0.688 0.312 0.000
E03.9 Hypothyroidism, unspecified
0.688 0.312 0.000
Chapter VII Diseases of the eye and adnexa
0.688 0.312 0.000
L84 Corns and callosities
0.686 0.313 0.000
D35.1 Parathyroid gland
0.686 0.314 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.683 0.317 0.000
I51.6 Cardiovascular disease, unspecified
0.683 0.317 0.000
I51.5 Myocardial degeneration
0.683 0.317 0.000
I51.4 Myocarditis, unspecified
0.683 0.317 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.683 0.317 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.683 0.317 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.683 0.317 0.000
I51.0 Cardiac septal defect, acquired
0.683 0.317 0.000
I35 Nonrheumatic aortic valve disorders
0.683 0.317 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.683 0.317 0.000
D22.9 Melanocytic naevi, unspecified
0.681 0.319 0.000
D22.2 Melanocytic naevi of ear and external auricular canal
0.681 0.319 0.000
D22.0 Melanocytic naevi of lip
0.681 0.319 0.000
D00-D09 In situ neoplasms
0.681 0.319 0.000
C44.6 Skin of upper limb, including shoulder
0.681 0.319 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.680 0.319 0.000
M91-M94 Chondropathies
0.680 0.319 0.000
M86-M90 Other osteopathies
0.680 0.319 0.000
M60-M63 Disorders of muscles
0.680 0.319 0.000
M00-M03 Infectious arthropathies
0.680 0.319 0.000
N43 Hydrocele and spermatocele
0.677 0.323 0.000
M75 Shoulder lesions
0.677 0.323 0.000
H80-H83 Diseases of inner ear
0.676 0.324 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.674 0.326 0.000
I34.0 Mitral (valve) insufficiency
0.673 0.327 0.000
I42 Cardiomyopathy
0.672 0.328 0.000
C64-C68 Malignant neoplasms of urinary tract
0.672 0.328 0.000
L89 Decubitus ulcer
0.671 0.329 0.000
D24 Benign neoplasm of breast
0.670 0.329 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.670 0.330 0.000
N42 Other disorders of prostate
0.669 0.330 0.000
L60-L75 Disorders of skin appendages
0.668 0.332 0.000
N48 Other disorders of penis
0.667 0.333 0.000
E04 Other non-toxic goitre
0.664 0.335 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.664 0.336 0.000
E11 Non-insulin-dependent diabetes mellitus
0.663 0.337 0.000
N17 Acute renal failure
0.663 0.337 0.000
L40-L45 Papulosquamous disorders
0.663 0.337 0.000
E13 Other specified diabetes mellitus
0.662 0.337 0.000
E12 Malnutrition-related diabetes mellitus
0.662 0.337 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.662 0.338 0.000
D46 Myelodysplastic syndromes
0.662 0.338 0.000
L85 Other epidermal thickening
0.661 0.339 0.000
I31 Other diseases of pericardium
0.661 0.339 0.000
E50-E64 Other nutritional deficiencies
0.661 0.339 0.000
C44.3 Skin of other and unspecified parts of face
0.660 0.340 0.000
D12.5 Sigmoid colon
0.660 0.340 0.000
M77 Other enthesopathies
0.660 0.340 0.000
E21.0 Primary hyperparathyroidism
0.657 0.343 0.000
V10-V19 Pedal cyclist injured in transport accident
0.657 0.343 0.000
Y44 Agents primarily affecting blood constituents
0.656 0.344 0.000
I77 Other disorders of arteries and arterioles
0.656 0.344 0.000
L53 Other erythematous conditions
0.656 0.344 0.000
Chapter I Certain infectious and parasitic diseases
0.655 0.345 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.655 0.345 0.000
I49.3 Ventricular premature depolarisation
0.655 0.345 0.000
I49.2 Junctional premature depolarisation
0.655 0.345 0.000
I49.1 Atrial premature depolarisation
0.655 0.345 0.000
C44.2 Skin of ear and external auricular canal
0.654 0.346 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.654 0.346 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.654 0.346 0.000
L94 Other localised connective tissue disorders
0.654 0.346 0.000
L93 Lupus erythematosus
0.654 0.346 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.654 0.346 0.000
L87 Transepidermal elimination disorders
0.654 0.346 0.000
L88 Pyoderma gangrenosum
0.654 0.346 0.000
L86 Keratoderma in diseases classified elsewhere
0.654 0.346 0.000
L83 Acanthosis nigricans
0.654 0.346 0.000
L80 Vitiligo
0.654 0.346 0.000
I24 Other acute ischaemic heart diseases
0.653 0.347 0.000
C51-C58 Malignant neoplasms of female genital organs
0.652 0.347 0.000
C44.5 Skin of trunk
0.653 0.347 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.650 0.349 0.000
I47.0 Reentry ventricular arrhythmia
0.650 0.349 0.000
N03 Chronic nephritic syndrome
0.650 0.350 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.649 0.351 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.646 0.354 0.000
D23.6 Skin of upper limb, including shoulder
0.646 0.354 0.000
E23 Hypofunction and other disorders of pituitary gland
0.646 0.354 0.000
W00-W19 Falls
0.645 0.355 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.644 0.356 0.000
N64 Other disorders of breast
0.644 0.356 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.643 0.357 0.000
C44.0 Skin of lip
0.643 0.357 0.000
D36.1 Peripheral nerves and autonomic nervous system
0.642 0.358 0.000
D35.9 Endocrine gland, unspecified
0.640 0.359 0.000
D35.8 Pluriglandular involvement
0.640 0.359 0.000
D35.7 Other specified endocrine glands
0.640 0.359 0.000
D35.6 Aortic body and other paraganglia
0.640 0.359 0.000
D35.5 Carotid body
0.640 0.359 0.000
D35.4 Pineal gland
0.640 0.359 0.000
D35.3 Craniopharyngeal duct
0.640 0.359 0.000
M22 Disorders of patella
0.640 0.360 0.000
I21 Acute myocardial infarction
0.637 0.363 0.000
M25 Other joint disorders, not elsewhere classified
0.637 0.363 0.000
I46.0 Cardiac arrest with successful resuscitation
0.637 0.363 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.633 0.367 0.000
H60-H62 Diseases of external ear
0.633 0.367 0.000
C43 Malignant melanoma of skin
0.633 0.367 0.000
E88 Other metabolic disorders
0.633 0.367 0.000
N19 Unspecified renal failure
0.632 0.368 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.632 0.368 0.000
I70 Atherosclerosis
0.631 0.368 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.631 0.369 0.000
Chapter V Mental and behavioural disorders
0.630 0.370 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.629 0.371 0.000
E34 Other endocrine disorders
0.629 0.371 0.000
E32 Diseases of thymus
0.629 0.371 0.000
E31 Polyglandular dysfunction
0.629 0.371 0.000
E30 Disorders of puberty, not elsewhere classified
0.629 0.371 0.000
E29 Testicular dysfunction
0.629 0.371 0.000
E28 Ovarian dysfunction
0.629 0.371 0.000
E26 Hyperaldosteronism
0.629 0.371 0.000
E25 Adrenogenital disorders
0.629 0.371 0.000
E24 Cushing's syndrome
0.629 0.371 0.000
E22 Hyperfunction of pituitary gland
0.629 0.371 0.000
E20 Hypoparathyroidism
0.629 0.371 0.000
M20.1 Hallux valgus (acquired)
0.629 0.371 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.628 0.372 0.000
Y35-Y36 Legal intervention and operations of war
0.628 0.372 0.000
Y10-Y34 Event of undetermined intent
0.628 0.372 0.000
Y00-Y09 Assault
0.628 0.372 0.000
X85-X99 Assault
0.628 0.372 0.000
X60-X84 Intentional self-harm
0.628 0.372 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.628 0.372 0.000
X50-X57 Overexertion, travel and privation
0.628 0.372 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.628 0.372 0.000
X30-X39 Exposure to forces of nature
0.628 0.372 0.000
X20-X29 Contact with venomous animals and plants
0.628 0.372 0.000
X10-X19 Contact with heat and hot substances
0.628 0.372 0.000
X00-X09 Exposure to smoke, fire and flames
0.628 0.372 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.628 0.372 0.000
W75-W84 Other accidental threats to breathing
0.628 0.372 0.000
W65-W74 Accidental drowning and submersion
0.628 0.372 0.000
W50-W64 Exposure to animate mechanical forces
0.628 0.372 0.000
W20-W49 Exposure to inanimate mechanical forces
0.628 0.372 0.000
V98-V99 Other and unspecified transport accidents
0.628 0.372 0.000
V95-V97 Air and space transport accidents
0.628 0.372 0.000
V90-V94 Water transport accidents
0.628 0.372 0.000
V80-V89 Other land transport accidents
0.628 0.372 0.000
V70-V79 Bus occupant injured in transport accident
0.628 0.372 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.628 0.372 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.628 0.372 0.000
V40-V49 Car occupant injured in transport accident
0.628 0.372 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.628 0.372 0.000
V20-V29 Motorcycle rider injured in transport accident
0.628 0.372 0.000
V01-V09 Pedestrian injured in transport accident
0.628 0.372 0.000
E05.8 Other thyrotoxicosis
0.625 0.375 0.000
E05.5 Thyroid crisis or storm
0.625 0.375 0.000
E05.4 Thyrotoxicosis factitia
0.625 0.375 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.625 0.375 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.625 0.375 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.625 0.375 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.625 0.375 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.623 0.377 0.000
C44.4 Skin of scalp and neck
0.622 0.378 0.000
E65-E68 Obesity and other hyperalimentation
0.621 0.379 0.000
N99-N99 Other disorders of the genitourinary system
0.620 0.380 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.619 0.380 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.619 0.380 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.619 0.380 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.619 0.380 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.619 0.380 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.619 0.380 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.619 0.380 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.619 0.380 0.000
D45 Polycythaemia vera
0.619 0.380 0.000
M45 Ankylosing spondylitis
0.619 0.381 0.000
D18 Haemangioma and lymphangioma, any site
0.619 0.381 0.000
L27 Dermatitis due to substances taken internally
0.619 0.381 0.000
H71 Cholesteatoma of middle ear
0.618 0.382 0.000
N25-N29 Other disorders of kidney and ureter
0.618 0.382 0.000
D17 Benign lipomatous neoplasm
0.618 0.382 0.000
H93 Other disorders of ear, not elsewhere classified
0.617 0.382 0.000
I45.9 Conduction disorder, unspecified
0.617 0.382 0.000
I45.8 Other specified conduction disorders
0.617 0.382 0.000
I45.5 Other specified heart block
0.617 0.382 0.000
I45.4 Nonspecific intraventricular block
0.617 0.382 0.000
I45.3 Trifascicular block
0.617 0.382 0.000
I45.2 Bifascicular block
0.617 0.382 0.000
I45.0 Right fascicular block
0.617 0.382 0.000
E83.5 Disorders of calcium metabolism
0.617 0.383 0.000
I73 Other peripheral vascular diseases
0.617 0.383 0.000
L90.0 Lichen sclerosus et atrophicus
0.616 0.384 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.615 0.384 0.000
D48.6 Breast
0.612 0.387 0.000
I22 Subsequent myocardial infarction
0.612 0.388 0.000
M43 Other deforming dorsopathies
0.612 0.388 0.000
N61 Inflammatory disorders of breast
0.611 0.389 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.610 0.390 0.000
D23.9 Skin, unspecified
0.609 0.391 0.000
D23.2 Skin of ear and external auricular canal
0.609 0.391 0.000
D23.0 Skin of lip
0.609 0.391 0.000
L30 Other dermatitis
0.609 0.391 0.000
M65-M68 Disorders of synovium and tendon
0.609 0.391 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.608 0.392 0.000
E85 Amyloidosis
0.608 0.392 0.000
E84 Cystic fibrosis
0.608 0.392 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.608 0.392 0.000
E79 Disorders of purine and pyrimidine metabolism
0.608 0.392 0.000
E77 Disorders of glycoprotein metabolism
0.608 0.392 0.000
E76 Disorders of glycosaminoglycan metabolism
0.608 0.392 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.608 0.392 0.000
E74 Other disorders of carbohydrate metabolism
0.608 0.392 0.000
E73 Lactose intolerance
0.608 0.392 0.000
E72 Other disorders of amino-acid metabolism
0.608 0.392 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.608 0.392 0.000
E70 Disorders of aromatic amino-acid metabolism
0.608 0.392 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.608 0.392 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.607 0.393 0.000
E06.9 Thyroiditis, unspecified
0.606 0.394 0.000
E06.5 Other chronic thyroiditis
0.606 0.394 0.000
E06.4 Drug-induced thyroiditis
0.606 0.394 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.606 0.394 0.000
E06.1 Subacute thyroiditis
0.606 0.394 0.000
E06.0 Acute thyroiditis
0.606 0.394 0.000
I20 Angina pectoris
0.606 0.394 0.000
I49.5 Sick sinus syndrome
0.605 0.395 0.000
M76 Enthesopathies of lower limb, excluding foot
0.604 0.396 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.604 0.396 0.000
M71 Other bursopathies
0.604 0.396 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.604 0.396 0.000
H74 Other disorders of middle ear and mastoid
0.604 0.396 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.603 0.397 0.000
I74 Arterial embolism and thrombosis
0.603 0.397 0.000
L29.9 Pruritus, unspecified
0.603 0.397 0.000
L50 Urticaria
0.603 0.397 0.000
M46 Other inflammatory spondylopathies
0.603 0.397 0.000
D32.9 Meninges, unspecified
0.602 0.397 0.000
D32.1 Spinal meninges
0.602 0.397 0.000
M24 Other specific joint derangements
0.601 0.399 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.599 0.401 0.000
I72 Other aneurysm
0.599 0.401 0.000
H90 Conductive and sensorineural hearing loss
0.598 0.401 0.000
G30-G32 Other degenerative diseases of the nervous system
0.598 0.402 0.000
M05-M14 Inflammatory polyarthropathies
0.597 0.403 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.597 0.403 0.000
I34.1 Mitral (valve) prolapse
0.597 0.403 0.000
N48.4 Impotence of organic origin
0.596 0.404 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.596 0.404 0.000
L28 Lichen simplex chronicus and prurigo
0.595 0.405 0.000
L25 Unspecified contact dermatitis
0.595 0.405 0.000
L24 Irritant contact dermatitis
0.595 0.405 0.000
L23 Allergic contact dermatitis
0.595 0.405 0.000
L21 Seborrhoeic dermatitis
0.595 0.405 0.000
L20 Atopic dermatitis
0.595 0.405 0.000
L26 Exfoliative dermatitis
0.595 0.405 0.000
L22 Diaper [napkin] dermatitis
0.595 0.405 0.000
E10.3 With ophthalmic complications
0.594 0.406 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.594 0.406 0.000
M47 Spondylosis
0.593 0.407 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.592 0.407 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.592 0.408 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.592 0.408 0.000
N46 Male infertility
0.592 0.408 0.000
N44 Torsion of testis
0.592 0.408 0.000
N30-N39 Other diseases of urinary system
0.591 0.409 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.590 0.409 0.000
D10.3 Other and unspecified parts of mouth
0.590 0.410 0.000
Chapter XXI Factors influencing health status and contact with health services
0.590 0.410 0.000
H92 Otalgia and effusion of ear
0.589 0.410 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.588 0.412 0.000
C44.8 Overlapping lesion of skin
0.588 0.412 0.000
D48.5 Skin
0.587 0.413 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.584 0.416 0.000
H43-H45 Disorders of vitreous body and globe
0.584 0.416 0.000
N17.9 Acute renal failure, unspecified
0.582 0.418 0.000
C44.7 Skin of lower limb, including hip
0.581 0.419 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.581 0.419 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.581 0.419 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.581 0.419 0.000
D48.1 Connective and other soft tissue
0.581 0.419 0.000
E14.8 With unspecified complications
0.580 0.419 0.000
E14.7 With multiple complications
0.580 0.419 0.000
E14.6 With other specified complications
0.580 0.419 0.000
E14.5 With peripheral circulatory complications
0.580 0.419 0.000
E14.4 With neurological complications
0.580 0.419 0.000
E14.3 With ophthalmic complications
0.580 0.419 0.000
E14.2 Withrenal complications
0.580 0.419 0.000
E14.1 With ketoacidosis
0.580 0.419 0.000
E14.0 With coma
0.580 0.419 0.000
N03.9 Unspecified
0.580 0.419 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.580 0.420 0.000
M34 Systemic sclerosis
0.580 0.420 0.000
M33 Dermatopolymyositis
0.580 0.420 0.000
M32 Systemic lupus erythematosus
0.580 0.420 0.000
M31 Other necrotising vasculopathies
0.580 0.420 0.000
M30 Polyarteritis nodosa and related conditions
0.580 0.420 0.000
M21 Other acquired deformities of limbs
0.580 0.420 0.000
I44 Atrioventricular and left bundle-branch block
0.579 0.420 0.000
M19.1 Posttraumatic arthrosis of other joints
0.578 0.421 0.000
E10.8 With unspecified complications
0.577 0.423 0.000
E10.7 With multiple complications
0.577 0.423 0.000
E10.6 With other specified complications
0.577 0.423 0.000
E10.5 With peripheral circulatory complications
0.577 0.423 0.000
E10.4 With neurological complications
0.577 0.423 0.000
E10.2 With renal complications
0.577 0.423 0.000
E10.1 With ketoacidosis
0.577 0.423 0.000
E10.0 With coma
0.577 0.423 0.000
M79.6 Pain in limb
0.577 0.423 0.000
M79.0 Rheumatism, unspecified
0.576 0.423 0.000
E03.8 Other specified hypothyroidism
0.576 0.424 0.000
E03.5 Myxoedema coma
0.576 0.424 0.000
E03.4 Atrophy of thyroid (acquired)
0.576 0.424 0.000
E03.3 Postinfectious hypothyroidism
0.576 0.424 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.576 0.424 0.000
E03.1 Congenital hypothyroidism without goitre
0.576 0.424 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.576 0.424 0.000
Y59 Other and unspecified vaccines and biological substances
0.574 0.426 0.000
Y58 Bacterial vaccines
0.574 0.426 0.000
Y57 Other and unspecified drugs and medicaments
0.574 0.426 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.574 0.426 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.574 0.426 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.574 0.426 0.000
Y52 Agents primarily affecting the cardiovascular system
0.574 0.426 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.574 0.426 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.574 0.426 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.574 0.426 0.000
Y48 Anaesthetics and therapeutic gases
0.574 0.426 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.574 0.426 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.574 0.426 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.574 0.426 0.000
Y40 Systemic antibiotics
0.574 0.426 0.000
N41.1 Chronic prostatitis
0.571 0.429 0.000
L54 Erythema in diseases classified elsewhere
0.571 0.429 0.000
L51 Erythema multiforme
0.571 0.429 0.000
L52 Erythema nodosum
0.571 0.429 0.000
N43.3 Hydrocele, unspecified
0.571 0.429 0.000
N64.1 Fat necrosis of breast
0.571 0.429 0.000
E16 Other disorders of pancreatic internal secretion
0.570 0.430 0.000
L29.0 Pruritus ani
0.570 0.430 0.000
I60-I69 Cerebrovascular diseases
0.568 0.431 0.000
H53-H54 Visual disturbances and blindness
0.568 0.432 0.000
D36.9 Benign neoplasm of unspecified site
0.567 0.433 0.000
D36.7 Other specified sites
0.567 0.433 0.000
D36.0 Lymph nodes
0.567 0.433 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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