TreeWAS – Variant ID: rs79340079

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	0.016	0.984
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.016	0.984
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.015	0.985
R50-R69 General symptoms and signs	0.015	0.985
Chapter II Neoplasms	0.014	0.985
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.014	0.986
Chapter XXI Factors influencing health status and contact with health services	0.014	0.986
Chapter XX External causes of morbidity and mortality	0.014	0.986
M15-M19 Arthrosis	0.013	0.987
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.012	0.987
R69 Unknown and unspecified causes of morbidity	0.012	0.988
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.012	0.988
C50-C50 Malignant neoplasm of breast	0.012	0.988
C43-C44 Melanoma and other malignant neoplasms of skin	0.012	0.988
R56 Convulsions, not elsewhere classified	0.012	0.988
Chapter XIV Diseases of the genitourinary system	0.012	0.988
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.012	0.988
Chapter X Diseases of the respiratory system	0.012	0.988
Chapter XXII Codes for special purposes	0.012	0.988
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.012	0.988
Chapter XVI Certain conditions originating in the perinatal period	0.012	0.988
Chapter XV Pregnancy, childbirth and the puerperium	0.012	0.988
Chapter XII Diseases of the skin and subcutaneous tissue	0.012	0.988
Chapter VIII Diseases of the ear and mastoid process	0.012	0.988
Chapter VII Diseases of the eye and adnexa	0.012	0.988
Chapter I Certain infectious and parasitic diseases	0.012	0.988
M50-M54 Other dorsopathies	0.012	0.988
M20-M25 Other joint disorders	0.012	0.988
R55 Syncope and collapse	0.012	0.988
R19 Other symptoms and signs involving the digestive system and abdomen	0.012	0.988
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.012	0.988
R95-R99 Ill-defined and unknown causes of mortality	0.011	0.988
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.011	0.988
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.011	0.988
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.011	0.988
R47-R49 Symptoms and signs involving speech and voice	0.011	0.988
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.011	0.988
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.011	0.988
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.011	0.988
R10 Abdominal and pelvic pain	0.012	0.988
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.011	0.988
M70-M79 Other soft tissue disorders	0.011	0.988
R13 Dysphagia	0.011	0.988
Chapter VI Diseases of the nervous system	0.011	0.989
Chapter XI Diseases of the digestive system	0.011	0.989
Chapter V Mental and behavioural disorders	0.011	0.989
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.011	0.989
D10-D36 Benign neoplasms	0.011	0.989
M17 Gonarthrosis [arthrosis of knee]	0.011	0.989
R30-R39 Symptoms and signs involving the urinary system	0.011	0.989
R51 Headache	0.011	0.989
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.011	0.989
M91-M94 Chondropathies	0.011	0.989
M86-M90 Other osteopathies	0.011	0.989
M80-M85 Disorders of bone density and structure	0.011	0.989
M65-M68 Disorders of synovium and tendon	0.011	0.989
M60-M63 Disorders of muscles	0.011	0.989
M45-M49 Spondylopathies	0.011	0.989
M40-M43 Deforming dorsopathies	0.011	0.989
M05-M14 Inflammatory polyarthropathies	0.011	0.989
M00-M03 Infectious arthropathies	0.011	0.989
W00-W19 Falls	0.011	0.989
Z96 Presence of other functional implants	0.011	0.989
R68 Other general symptoms and signs	0.011	0.989
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.011	0.989
R63 Symptoms and signs concerning food and fluid intake	0.011	0.989
R62 Lack of expected normal physiological development	0.011	0.989
R61 Hyperhidrosis	0.011	0.989
R60 Oedema, not elsewhere classified	0.011	0.989
R59 Enlarged lymph nodes	0.011	0.989
R57 Shock, not elsewhere classified	0.011	0.989
R52 Pain, not elsewhere classified	0.011	0.989
R50 Fever of unknown origin	0.011	0.989
R64 Cachexia	0.011	0.989
R58 Haemorrhage, not elsewhere classified	0.011	0.989
R54 Senility	0.011	0.989
R53 Malaise and fatigue	0.011	0.989
D37-D48 Neoplasms of uncertain or unknown behaviour	0.011	0.989
D00-D09 In situ neoplasms	0.011	0.989
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.011	0.989
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.011	0.989
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.011	0.989
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.011	0.989
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.011	0.989
C64-C68 Malignant neoplasms of urinary tract	0.011	0.989
C60-C63 Malignant neoplasms of male genital organs	0.011	0.989
C51-C58 Malignant neoplasms of female genital organs	0.011	0.989
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.011	0.989
C40-C41 Malignant neoplasms of bone and articular cartilage	0.011	0.989
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.011	0.989
C15-C26 Malignant neoplasms of digestive organs	0.011	0.989
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.011	0.989
Chapter IV Endocrine, nutritional and metabolic diseases	0.010	0.989
C50 Malignant neoplasm of breast	0.010	0.989
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.010	0.990
C44 Other malignant neoplasms of skin	0.010	0.990
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.010	0.990
R18 Ascites	0.010	0.990
R17 Unspecified jaundice	0.010	0.990
R15 Faecal incontinence	0.010	0.990
R14 Flatulence and related conditions	0.010	0.990
R12 Heartburn	0.010	0.990
Z98 Other postsurgical states	0.010	0.990
R56.8 Other and unspecified convulsions	0.010	0.990
Z00-Z13 Persons encountering health services for examination and investigation	0.010	0.990
Z85 Personal history of malignant neoplasm	0.010	0.990
Chapter IX Diseases of the circulatory system	0.010	0.990
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.010	0.990
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.010	0.990
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.010	0.990
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.010	0.990
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.010	0.990
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.010	0.990
Y60-Y69 Misadventures to patients during surgical and medical care	0.010	0.990
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.010	0.990
Y35-Y36 Legal intervention and operations of war	0.010	0.990
Y10-Y34 Event of undetermined intent	0.010	0.990
Y00-Y09 Assault	0.010	0.990
X85-X99 Assault	0.010	0.990
X60-X84 Intentional self-harm	0.010	0.990
X58-X59 Accidental exposure to other and unspecified factors	0.010	0.990
X50-X57 Overexertion, travel and privation	0.010	0.990
X40-X49 Accidental poisoning by and exposure to noxious substances	0.010	0.990
X30-X39 Exposure to forces of nature	0.010	0.990
X20-X29 Contact with venomous animals and plants	0.010	0.990
X10-X19 Contact with heat and hot substances	0.010	0.990
X00-X09 Exposure to smoke, fire and flames	0.010	0.990
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.010	0.990
W75-W84 Other accidental threats to breathing	0.010	0.990
W65-W74 Accidental drowning and submersion	0.010	0.990
W50-W64 Exposure to animate mechanical forces	0.010	0.990
W20-W49 Exposure to inanimate mechanical forces	0.010	0.990
V98-V99 Other and unspecified transport accidents	0.010	0.990
V95-V97 Air and space transport accidents	0.010	0.990
V90-V94 Water transport accidents	0.010	0.990
V80-V89 Other land transport accidents	0.010	0.990
V70-V79 Bus occupant injured in transport accident	0.010	0.990
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.010	0.990
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.010	0.990
V40-V49 Car occupant injured in transport accident	0.010	0.990
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.010	0.990
V20-V29 Motorcycle rider injured in transport accident	0.010	0.990
V10-V19 Pedal cyclist injured in transport accident	0.010	0.990
V01-V09 Pedestrian injured in transport accident	0.010	0.990
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.010	0.990
M17.9 Gonarthrosis, unspecified	0.010	0.990
R19.4 Change in bowel habit	0.010	0.990
Z70-Z76 Persons encountering health services in other circumstances	0.010	0.990
M16 Coxarthrosis [arthrosis of hip]	0.010	0.990
M20 Acquired deformities of fingers and toes	0.010	0.990
R10.4 Other and unspecified abdominal pain	0.010	0.990
M51 Other intervertebral disk disorders	0.009	0.990
R11 Nausea and vomiting	0.009	0.990
Z96.6 Presence of orthopaedic joint implants	0.009	0.990
Z40-Z54 Persons encountering health services for specific procedures and health care	0.009	0.990
M19 Other arthrosis	0.009	0.991
M18 Arthrosis of first carpometacarpal joint	0.009	0.991
M15 Polyarthrosis	0.009	0.991
Z95 Presence of cardiac and vascular implants and grafts	0.009	0.991
S50-S59 Injuries to the elbow and forearm	0.009	0.991
K40-K46 Hernia	0.009	0.991
C44.3 Skin of other and unspecified parts of face	0.009	0.991
R79 Other abnormal findings of blood chemistry	0.009	0.991
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.009	0.991
Z97 Presence of other devices	0.009	0.991
Z94 Transplanted organ and tissue status	0.009	0.991
Z93 Artificial opening status	0.009	0.991
Z91 Personal history of risk-factors, not elsewhere classified	0.009	0.991
Z90 Acquired absence of organs, not elsewhere classified	0.009	0.991
Z89 Acquired absence of limb	0.009	0.991
Z84 Family history of other conditions	0.009	0.991
Z83 Family history of other specific disorders	0.009	0.991
Z81 Family history of mental and behavioural disorders	0.009	0.991
M75 Shoulder lesions	0.009	0.991
Z92 Personal history of medical treatment	0.009	0.991
Z86 Personal history of certain other diseases	0.009	0.991
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.009	0.991
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.009	0.991
T79-T79 Certain early complications of trauma	0.009	0.991
T66-T78 Other and unspecified effects of external causes	0.009	0.991
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.009	0.991
T36-T50 Poisoning by drugs, medicaments and biological substances	0.009	0.991
T33-T35 Frostbite	0.009	0.991
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.009	0.991
T26-T28 Burns and corrosions confined to eye and internal organs	0.009	0.991
T20-T25 Burns and corrosions of external body surface, specified by site	0.009	0.991
T15-T19 Effects of foreign body entering through natural orifice	0.009	0.991
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.009	0.991
T00-T07 Injuries involving multiple body regions	0.009	0.991
S90-S99 Injuries to the ankle and foot	0.009	0.991
S80-S89 Injuries to the knee and lower leg	0.009	0.991
S70-S79 Injuries to the hip and thigh	0.009	0.991
S60-S69 Injuries to the wrist and hand	0.009	0.991
S40-S49 Injuries to the shoulder and upper arm	0.009	0.991
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.009	0.991
S20-S29 Injuries to the thorax	0.009	0.991
S10-S19 Injuries to the neck	0.009	0.991
S00-S09 Injuries to the head	0.009	0.991
N40-N51 Diseases of male genital organs	0.009	0.991
N30-N39 Other diseases of urinary system	0.009	0.991
C43 Malignant melanoma of skin	0.009	0.991
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.009	0.991
Z80 Family history of malignant neoplasm	0.009	0.991
J40-J47 Chronic lower respiratory diseases	0.009	0.991
R56.0 Febrile convulsions	0.009	0.991
C50.4 Upper-outer quadrant of breast	0.009	0.991
N99-N99 Other disorders of the genitourinary system	0.009	0.991
N80-N98 Noninflammatory disorders of female genital tract	0.009	0.991
N70-N77 Inflammatory diseases of female pelvic organs	0.009	0.991
N60-N64 Disorders of breast	0.009	0.991
N25-N29 Other disorders of kidney and ureter	0.009	0.991
N20-N23 Urolithiasis	0.009	0.991
N17-N19 Renal failure	0.009	0.991
N10-N16 Renal tubulo-interstitial diseases	0.009	0.991
N00-N08 Glomerular diseases	0.009	0.991
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.009	0.991
R78 Findings of drugs and other substances, not normally found in blood	0.009	0.991
R77 Other abnormalities of plasma proteins	0.009	0.991
R76 Other abnormal immunological findings in serum	0.009	0.991
R74 Abnormal serum enzyme levels	0.009	0.991
R73 Elevated blood glucose level	0.009	0.991
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.009	0.991
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.009	0.991
R72 Abnormality of white blood cells, not elsewhere classified	0.009	0.991
R71 Abnormality of red blood cells	0.009	0.991
J20-J22 Other acute lower respiratory infections	0.009	0.991
J95-J99 Other diseases of the respiratory system	0.009	0.991
J90-J94 Other diseases of pleura	0.009	0.991
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.009	0.991
J80-J84 Other respiratory diseases principally affecting the interstitium	0.009	0.991
J60-J70 Lung diseases due to external agents	0.009	0.991
J30-J39 Other diseases of upper respiratory tract	0.009	0.991
J09-J18 Influenza and pneumonia	0.009	0.991
J00-J06 Acute upper respiratory infections	0.009	0.991
R10.1 Pain localised to upper abdomen	0.009	0.991
W19 Unspecified fall	0.009	0.991
Z98.0 Intestinal bypass and anastomosis status	0.009	0.991
B99-B99 Other infectious diseases	0.009	0.991
B95-B98 Bacterial, viral and other infectious agents	0.009	0.991
B90-B94 Sequelae of infectious and parasitic diseases	0.009	0.991
B85-B89 Pediculosis, acariasis and other infestations	0.009	0.991
B65-B83 Helminthiases	0.009	0.991
B50-B64 Protozoal diseases	0.009	0.991
B35-B49 Mycoses	0.009	0.991
B25-B34 Other viral diseases	0.009	0.991
B20-B24 Human immunodeficiency virus [HIV] disease	0.009	0.991
B15-B19 Viral hepatitis	0.009	0.991
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.009	0.991
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.009	0.991
A80-A89 Viral infections of the central nervous system	0.009	0.991
A75-A79 Rickettsioses	0.009	0.991
A70-A74 Other diseases caused by chlamydiae	0.009	0.991
A65-A69 Other spirochaetal diseases	0.009	0.991
A50-A64 Infections with a predominantly sexual mode of transmission	0.009	0.991
A30-A49 Other bacterial diseases	0.009	0.991
A20-A28 Certain zoonotic bacterial diseases	0.009	0.991
A15-A19 Tuberculosis	0.009	0.991
A00-A09 Intestinal infectious diseases	0.009	0.991
H55-H59 Other disorders of eye and adnexa	0.009	0.991
H53-H54 Visual disturbances and blindness	0.009	0.991
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.009	0.991
H46-H48 Disorders of optic nerve and visual pathways	0.009	0.991
H43-H45 Disorders of vitreous body and globe	0.009	0.991
H40-H42 Glaucoma	0.009	0.991
H30-H36 Disorders of choroid and retina	0.009	0.991
H25-H28 Disorders of lens	0.009	0.991
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.009	0.991
H10-H13 Disorders of conjunctiva	0.009	0.991
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.009	0.991
H90-H95 Other disorders of ear	0.009	0.991
H80-H83 Diseases of inner ear	0.009	0.991
H65-H75 Diseases of middle ear and mastoid	0.009	0.991
H60-H62 Diseases of external ear	0.009	0.991
L80-L99 Other disorders of the skin and subcutaneous tissue	0.009	0.991
L60-L75 Disorders of skin appendages	0.009	0.991
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.009	0.991
L50-L54 Urticaria and erythema	0.009	0.991
L40-L45 Papulosquamous disorders	0.009	0.991
L20-L30 Dermatitis and eczema	0.009	0.991
L10-L14 Bullous disorders	0.009	0.991
L00-L08 Infections of the skin and subcutaneous tissue	0.009	0.991
O94-O99 Other obstetric conditions, not elsewhere classified	0.009	0.991
O85-O92 Complications predominantly related to the puerperium	0.009	0.991
O80-O84 Delivery	0.009	0.991
O60-O75 Complications of labour and delivery	0.009	0.991
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.009	0.991
O20-O29 Other maternal disorders predominantly related to pregnancy	0.009	0.991
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.009	0.991
O00-O08 Pregnancy with abortive outcome	0.009	0.991
P90-P96 Other disorders originating in the perinatal period	0.009	0.991
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.009	0.991
P75-P78 Digestive system disorders of fetus and newborn	0.009	0.991
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.009	0.991
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.009	0.991
P35-P39 Infections specific to the perinatal period	0.009	0.991
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.009	0.991
P10-P15 Birth trauma	0.009	0.991
P05-P08 Disorders related to length of gestation and fetal growth	0.009	0.991
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.009	0.991
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.009	0.991
Q80-Q89 Other congenital malformations	0.009	0.991
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.009	0.991
Q60-Q64 Congenital malformations of the urinary system	0.009	0.991
Q50-Q56 Congenital malformations of genital organs	0.009	0.991
Q38-Q45 Other congenital malformations of the digestive system	0.009	0.991
Q35-Q37 Cleft lip and cleft palate	0.009	0.991
Q30-Q34 Congenital malformations of the respiratory system	0.009	0.991
Q20-Q28 Congenital malformations of the circulatory system	0.009	0.991
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.009	0.991
Q00-Q07 Congenital malformations of the nervous system	0.009	0.991
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.009	0.991
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.009	0.991
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.009	0.991
M35 Other systemic involvement of connective tissue	0.009	0.991
M34 Systemic sclerosis	0.009	0.991
M33 Dermatopolymyositis	0.009	0.991
M32 Systemic lupus erythematosus	0.009	0.991
M31 Other necrotising vasculopathies	0.009	0.991
M30 Polyarteritis nodosa and related conditions	0.009	0.991
M25 Other joint disorders, not elsewhere classified	0.009	0.991
M24 Other specific joint derangements	0.009	0.991
M23 Internal derangement of knee	0.009	0.991
M22 Disorders of patella	0.009	0.991
M21 Other acquired deformities of limbs	0.009	0.991
M54 Dorsalgia	0.009	0.991
M53 Other dorsopathies, not elsewhere classified	0.009	0.991
M50 Cervical disk disorders	0.009	0.991
D50-D53 Nutritional anaemias	0.008	0.991
Z30 Contraceptive management	0.009	0.991
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.008	0.991
R19.6 Halitosis	0.008	0.991
R19.5 Other fecal abnormalities	0.008	0.991
R19.3 Abdominal rigidity	0.008	0.991
R19.2 Visible peristalsis	0.008	0.991
R19.1 Abnormal bowel sounds	0.008	0.991
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.008	0.991
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.008	0.991
R23 Other skin changes	0.008	0.991
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.008	0.991
R20 Disturbances of skin sensation	0.008	0.991
R21 Rash and other nonspecific skin eruption	0.008	0.991
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.008	0.991
R27 Other lack of coordination	0.008	0.991
R26 Abnormalities of gait and mobility	0.008	0.991
R25 Abnormal involuntary movements	0.008	0.991
R46 Symptoms and signs involving appearance and behaviour	0.008	0.991
R45 Symptoms and signs involving emotional state	0.008	0.991
R44 Other symptoms and signs involving general sensations and perceptions	0.008	0.991
R43 Disturbances of smell and taste	0.008	0.991
R41 Other symptoms and signs involving cognitive functions and awareness	0.008	0.991
R40 Somnolence, stupor and coma	0.008	0.991
R42 Dizziness and giddiness	0.008	0.991
R49 Voice disturbances	0.008	0.991
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.008	0.991
R47 Speech disturbances, not elsewhere classified	0.008	0.991
R82 Other abnormal findings in urine	0.008	0.991
R81 Glycosuria	0.008	0.991
R80 Isolated proteinuria	0.008	0.991
R89 Abnormal findings in specimens from other organs, systems and tissues	0.008	0.991
R87 Abnormal findings in specimens from female genital organs	0.008	0.991
R86 Abnormal findings in specimens from male genital organs	0.008	0.991
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.008	0.991
R84 Abnormal findings in specimens from respiratory organs and thorax	0.008	0.991
R83 Abnormal findings in cerebrospinal fluid	0.008	0.991
R94 Abnormal results of function studies	0.008	0.991
R93 Abnormal findings on diagnostic imaging of other body structures	0.008	0.991
R90 Abnormal findings on diagnostic imaging of central nervous system	0.008	0.991
R92 Abnormal findings on diagnostic imaging of breast	0.008	0.991
R91 Abnormal findings on diagnostic imaging of lung	0.008	0.991
R96 Other sudden death, cause unknown	0.008	0.991
R95 Sudden infant death syndrome	0.008	0.991
R99 Other ill-defined and unspecified causes of mortality	0.008	0.991
R98 Unattended death	0.008	0.991
R10.3 Pain localised to other parts of lower abdomen	0.008	0.991
R10.2 Pelvic and perineal pain	0.008	0.991
R10.0 Acute abdomen	0.008	0.991
D80-D89 Certain disorders involving the immune mechanism	0.008	0.991
D70-D77 Other diseases of blood and blood-forming organs	0.008	0.991
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.008	0.991
D55-D59 Haemolytic anaemias	0.008	0.991
Y83.8 Other surgical procedures	0.008	0.991
M79 Other soft tissue disorders, not elsewhere classified	0.008	0.991
M77 Other enthesopathies	0.008	0.991
M76 Enthesopathies of lower limb, excluding foot	0.008	0.991
M73 Soft tissue disorders in diseases classified elsewhere	0.008	0.991
M72 Fibroblastic disorders	0.008	0.991
M71 Other bursopathies	0.008	0.991
M70 Soft tissue disorders related to use, overuse and pressure	0.008	0.991
C50.9 Breast, unspecified	0.008	0.991
Y83.1 Surgical operation with implant of artificial internal device	0.008	0.992
R06 Abnormalities of breathing	0.008	0.992
G90-G99 Other disorders of the nervous system	0.008	0.992
G80-G83 Cerebral palsy and other paralytic syndromes	0.008	0.992
G70-G73 Diseases of myoneural junction and muscle	0.008	0.992
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.008	0.992
G40-G47 Episodic and paroxysmal disorders	0.008	0.992
G35-G37 Demyelinating diseases of the central nervous system	0.008	0.992
G30-G32 Other degenerative diseases of the nervous system	0.008	0.992
G20-G26 Extrapyramidal and movement disorders	0.008	0.992
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.008	0.992
G00-G09 Inflammatory diseases of the central nervous system	0.008	0.992
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.008	0.992
F99-F99 Unspecified mental disorder	0.008	0.992
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.008	0.992
F80-F89 Disorders of psychological development	0.008	0.992
F70-F79 Mental retardation	0.008	0.992
F60-F69 Disorders of adult personality and behaviour	0.008	0.992
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.008	0.992
F40-F48 Neurotic, stress-related and somatoform disorders	0.008	0.992
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.008	0.992
F00-F09 Organic, including symptomatic, mental disorders	0.008	0.992
K90-K93 Other diseases of the digestive system	0.008	0.992
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.008	0.992
K70-K77 Diseases of liver	0.008	0.992
K65-K67 Diseases of peritoneum	0.008	0.992
K35-K38 Diseases of appendix	0.008	0.992
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.008	0.992
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.008	0.992
R04 Haemorrhage from respiratory passages	0.008	0.992
R03 Abnormal blood-pressure reading, without diagnosis	0.008	0.992
R01 Cardiac murmurs and other cardiac sounds	0.008	0.992
R00 Abnormalities of heart beat	0.008	0.992
R05 Cough	0.008	0.992
R02 Gangrene, not elsewhere classified	0.008	0.992
D36 Benign neoplasm of other and unspecified sites	0.008	0.992
D35 Benign neoplasm of other and unspecified endocrine glands	0.008	0.992
D33 Benign neoplasm of brain and other parts of central nervous system	0.008	0.992
D32 Benign neoplasm of meninges	0.008	0.992
D31 Benign neoplasm of eye and adnexa	0.008	0.992
D30 Benign neoplasm of urinary organs	0.008	0.992
D29 Benign neoplasm of male genital organs	0.008	0.992
D28 Benign neoplasm of other and unspecified female genital organs	0.008	0.992
D26 Other benign neoplasms of uterus	0.008	0.992
D25 Leiomyoma of uterus	0.008	0.992
D23 Other benign neoplasms of skin	0.008	0.992
D22 Melanocytic naevi	0.008	0.992
D21 Other benign neoplasms of connective and other soft tissue	0.008	0.992
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.008	0.992
D19 Benign neoplasm of mesothelial tissue	0.008	0.992
D18 Haemangioma and lymphangioma, any site	0.008	0.992
D17 Benign lipomatous neoplasm	0.008	0.992
D16 Benign neoplasm of bone and articular cartilage	0.008	0.992
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.008	0.992
D14 Benign neoplasm of middle ear and respiratory system	0.008	0.992
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.008	0.992
D11 Benign neoplasm of major salivary glands	0.008	0.992
D10 Benign neoplasm of mouth and pharynx	0.008	0.992
D34 Benign neoplasm of thyroid gland	0.008	0.992
D27 Benign neoplasm of ovary	0.008	0.992
D24 Benign neoplasm of breast	0.008	0.992
M17.5 Other secondary gonarthrosis	0.008	0.992
M17.4 Other secondary gonarthrosis, bilateral	0.008	0.992
M17.3 Other posttraumatic gonarthrosis	0.008	0.992
M17.2 Posttraumatic gonarthrosis, bilateral	0.008	0.992
M17.1 Other primary gonarthrosis	0.008	0.992
M17.0 Primary gonarthrosis, bilateral	0.008	0.992
R39 Other symptoms and signs involving the urinary system	0.008	0.992
R30 Pain associated with micturition	0.008	0.992
R36 Urethral discharge	0.008	0.992
R35 Polyuria	0.008	0.992
R34 Anuria and oliguria	0.008	0.992
R33 Retention of urine	0.008	0.992
R32 Unspecified urinary incontinence	0.008	0.992
F30-F39 Mood [affective] disorders	0.008	0.992
Z85.3 Personal history of malignant neoplasm of breast	0.008	0.992
D60-D64 Aplastic and other anaemias	0.008	0.992
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.008	0.992
M20.1 Hallux valgus (acquired)	0.008	0.992
M51.2 Other specified intervertebral disk displacement	0.008	0.992
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.008	0.992
M02 Reactive arthropathies	0.008	0.992
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.008	0.992
M00 Pyogenic arthritis	0.008	0.992
M14 Arthropathies in other diseases classified elsewhere	0.008	0.992
M13 Other arthritis	0.008	0.992
M12 Other specific arthropathies	0.008	0.992
M11 Other crystal arthropathies	0.008	0.992
M10 Gout	0.008	0.992
M09 Juvenile arthritis in diseases classified elsewhere	0.008	0.992
M08 Juvenile arthritis	0.008	0.992
M07 Psoriatic and enteropathic arthropathies	0.008	0.992
M06 Other rheumatoid arthritis	0.008	0.992
M05 Seropositive rheumatoid arthritis	0.008	0.992
M43 Other deforming dorsopathies	0.008	0.992
M42 Spinal osteochondrosis	0.008	0.992
M41 Scoliosis	0.008	0.992
M40 Kyphosis and lordosis	0.008	0.992
M49 Spondylopathies in diseases classified elsewhere	0.008	0.992
M48 Other spondylopathies	0.008	0.992
M47 Spondylosis	0.008	0.992
M46 Other inflammatory spondylopathies	0.008	0.992
M45 Ankylosing spondylitis	0.008	0.992
M63 Disorders of muscle in diseases classified elsewhere	0.008	0.992
M62 Other disorders of muscle	0.008	0.992
M61 Calcification and ossification of muscle	0.008	0.992
M60 Myositis	0.008	0.992
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.008	0.992
M67 Other disorders of synovium and tendon	0.008	0.992
M66 Spontaneous rupture of synovium and tendon	0.008	0.992
M65 Synovitis and tenosynovitis	0.008	0.992

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations