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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs80058873
log Bayes Factor = 13.5077
Chromosome 11   position 93,959,955  (GRCh37) Explore rs80058873 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
M45-M49 Spondylopathies
0.998 0.002 0.000
M47 Spondylosis
0.997 0.003 0.000
R50-R69 General symptoms and signs
0.996 0.004 0.000
E11 Non-insulin-dependent diabetes mellitus
0.995 0.005 0.000
Chapter V Mental and behavioural disorders
0.993 0.007 0.000
M47.8 Other spondylosis
0.992 0.008 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.991 0.009 0.000
R10 Abdominal and pelvic pain
0.991 0.009 0.000
R10.3 Pain localised to other parts of lower abdomen
0.988 0.012 0.000
I25 Chronic ischaemic heart disease
0.988 0.012 0.000
M47.82 Other spondylosis (Cervical region)
0.987 0.013 0.000
R50 Fever of unknown origin
0.986 0.014 0.000
E11.9 Without complications
0.986 0.014 0.000
F30-F39 Mood [affective] disorders
0.980 0.020 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.980 0.020 0.000
R50.9 Fever, unspecified
0.974 0.026 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.972 0.028 0.000
Chapter XX External causes of morbidity and mortality
0.967 0.033 0.000
E00-E07 Disorders of thyroid gland
0.966 0.034 0.000
I25.2 Old myocardial infarction
0.964 0.036 0.000
R63 Symptoms and signs concerning food and fluid intake
0.961 0.039 0.000
I22 Subsequent myocardial infarction
0.960 0.040 0.000
I10-I15 Hypertensive diseases
0.958 0.042 0.000
F31 Bipolar affective disorder
0.958 0.042 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.955 0.045 0.000
I95 Hypotension
0.952 0.048 0.000
R10.1 Pain localised to upper abdomen
0.949 0.051 0.000
M70-M79 Other soft tissue disorders
0.944 0.056 0.000
E14 Unspecified diabetes mellitus
0.942 0.058 0.000
I95.9 Hypotension, unspecified
0.939 0.061 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.939 0.061 0.000
R63.4 Abnormal weight loss
0.935 0.065 0.000
E10 Insulin-dependent diabetes mellitus
0.932 0.068 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.929 0.071 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.926 0.074 0.000
I10 Essential (primary) hypertension
0.925 0.075 0.000
R52 Pain, not elsewhere classified
0.923 0.077 0.000
M47.9 Spondylosis, unspecified
0.923 0.077 0.000
M20-M25 Other joint disorders
0.919 0.081 0.000
I20 Angina pectoris
0.916 0.084 0.000
F31.9 Bipolar affective disorder, unspecified
0.914 0.086 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.912 0.088 0.000
I77 Other disorders of arteries and arterioles
0.903 0.097 0.000
E14.9 Without complications
0.902 0.098 0.000
E10.9 Without complications
0.902 0.098 0.000
M25 Other joint disorders, not elsewhere classified
0.900 0.100 0.000
R10.0 Acute abdomen
0.900 0.100 0.000
I72 Other aneurysm
0.898 0.102 0.000
R52.1 Chronic intractable pain
0.895 0.105 0.000
M25.5 Pain in joint
0.891 0.109 0.000
R13 Dysphagia
0.889 0.111 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.889 0.111 0.000
I77.1 Stricture of artery
0.876 0.124 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.872 0.128 0.000
R51 Headache
0.865 0.135 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.864 0.136 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.862 0.138 0.000
E11.2 With renal complications
0.862 0.138 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.859 0.141 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.857 0.143 0.000
E03 Other hypothyroidism
0.854 0.146 0.000
I20.0 Unstable angina
0.849 0.151 0.000
M25.57 Pain in joint (Ankle and foot)
0.849 0.151 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.846 0.154 0.000
I74 Arterial embolism and thrombosis
0.845 0.155 0.000
F41 Other anxiety disorders
0.844 0.156 0.000
E05.9 Thyrotoxicosis, unspecified
0.838 0.162 0.000
M05-M14 Inflammatory polyarthropathies
0.835 0.165 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.834 0.166 0.000
O60-O75 Complications of labour and delivery
0.834 0.166 0.000
R50.0 Fever with chills
0.831 0.169 0.000
E65-E68 Obesity and other hyperalimentation
0.830 0.170 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.830 0.170 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.829 0.171 0.000
I72.4 Aneurysm of artery of lower extremity
0.829 0.171 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.827 0.173 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.825 0.175 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.824 0.176 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.821 0.179 0.000
M47.86 Other spondylosis (Lumbar region)
0.820 0.179 0.000
V80-V89 Other land transport accidents
0.820 0.180 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.819 0.181 0.000
Chapter XXII Codes for special purposes
0.815 0.185 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.814 0.186 0.000
I25.3 Aneurysm of heart
0.813 0.187 0.000
M75 Shoulder lesions
0.813 0.187 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.812 0.188 0.000
M25.51 Pain in joint (Shoulder region)
0.805 0.195 0.000
F40 Phobic anxiety disorders
0.799 0.201 0.000
M86-M90 Other osteopathies
0.797 0.203 0.000
E50-E64 Other nutritional deficiencies
0.795 0.205 0.000
V20-V29 Motorcycle rider injured in transport accident
0.793 0.207 0.000
F30 Manic episode
0.792 0.208 0.000
E11.4 With neurological complications
0.792 0.208 0.000
R12 Heartburn
0.791 0.209 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.791 0.209 0.000
F60-F69 Disorders of adult personality and behaviour
0.788 0.212 0.000
M91-M94 Chondropathies
0.787 0.213 0.000
F32 Depressive episode
0.783 0.217 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.783 0.217 0.000
M35 Other systemic involvement of connective tissue
0.782 0.218 0.000
Chapter XI Diseases of the digestive system
0.782 0.218 0.000
E04 Other non-toxic goitre
0.781 0.219 0.000
I30-I52 Other forms of heart disease
0.779 0.221 0.000
E11.5 With peripheral circulatory complications
0.777 0.222 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.775 0.225 0.000
E03.9 Hypothyroidism, unspecified
0.774 0.226 0.000
M40-M43 Deforming dorsopathies
0.772 0.228 0.000
R63.0 Anorexia
0.772 0.228 0.000
M48 Other spondylopathies
0.771 0.229 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.769 0.231 0.000
M60-M63 Disorders of muscles
0.768 0.231 0.000
M24 Other specific joint derangements
0.767 0.233 0.000
I78 Diseases of capillaries
0.765 0.235 0.000
Chapter II Neoplasms
0.765 0.235 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.765 0.235 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.761 0.239 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.760 0.240 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.758 0.242 0.000
M13 Other arthritis
0.757 0.243 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.756 0.244 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.754 0.246 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.754 0.246 0.000
M46 Other inflammatory spondylopathies
0.753 0.247 0.000
K70-K77 Diseases of liver
0.752 0.248 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.751 0.249 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.750 0.250 0.000
E13 Other specified diabetes mellitus
0.749 0.251 0.000
M75.1 Rotator cuff syndrome
0.748 0.252 0.000
F33 Recurrent depressive disorder
0.747 0.253 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.745 0.255 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.745 0.255 0.000
M47.1 Other spondylosis with myelopathy
0.742 0.258 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.742 0.258 0.000
I95.2 Hypotension due to drugs
0.741 0.259 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.740 0.260 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.740 0.260 0.000
X60-X84 Intentional self-harm
0.739 0.261 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.738 0.262 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.737 0.263 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.737 0.263 0.000
E11.1 With ketoacidosis
0.737 0.263 0.000
M25.50 Pain in joint (Multiple sites)
0.737 0.263 0.000
T43.2 Other and unspecified antidepressants
0.737 0.263 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.736 0.264 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.736 0.264 0.000
F41.2 Mixed anxiety and depressive disorder
0.736 0.264 0.000
S90-S99 Injuries to the ankle and foot
0.731 0.268 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.731 0.269 0.000
R53 Malaise and fatigue
0.731 0.269 0.000
Y40 Systemic antibiotics
0.731 0.269 0.000
M25.59 Pain in joint (Site unspecified)
0.729 0.271 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.729 0.271 0.000
C15-C26 Malignant neoplasms of digestive organs
0.729 0.271 0.000
Y57 Other and unspecified drugs and medicaments
0.728 0.271 0.000
I60-I69 Cerebrovascular diseases
0.728 0.272 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.728 0.272 0.000
V10-V19 Pedal cyclist injured in transport accident
0.727 0.273 0.000
M47.89 Other spondylosis (Site unspecified)
0.726 0.273 0.000
D12.8 Rectum
0.726 0.274 0.000
I38 Endocarditis, valve unspecified
0.724 0.276 0.000
K90-K93 Other diseases of the digestive system
0.723 0.277 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.722 0.278 0.000
D12.0 Caecum
0.722 0.278 0.000
M79.6 Pain in limb
0.721 0.279 0.000
M35.0 Sicca syndrome [Sjogren]
0.721 0.279 0.000
R61 Hyperhidrosis
0.720 0.280 0.000
I73 Other peripheral vascular diseases
0.719 0.281 0.000
R15 Faecal incontinence
0.719 0.281 0.000
I20.8 Other forms of angina pectoris
0.719 0.281 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
F41.9 Anxiety disorder, unspecified
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
O85-O92 Complications predominantly related to the puerperium
0.716 0.284 0.000
M49 Spondylopathies in diseases classified elsewhere
0.716 0.284 0.000
F43 Reaction to severe stress, and adjustment disorders
0.715 0.285 0.000
R47-R49 Symptoms and signs involving speech and voice
0.715 0.285 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.714 0.285 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.714 0.286 0.000
R62 Lack of expected normal physiological development
0.714 0.286 0.000
R64 Cachexia
0.714 0.286 0.000
R58 Haemorrhage, not elsewhere classified
0.714 0.286 0.000
R52.9 Pain, unspecified
0.714 0.286 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.714 0.286 0.000
E11.8 With unspecified complications
0.713 0.286 0.000
E11.7 With multiple complications
0.713 0.286 0.000
E11.6 With other specified complications
0.713 0.286 0.000
E11.0 With coma
0.713 0.286 0.000
M25.3 Other instability of joint
0.713 0.287 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.712 0.288 0.000
C20 Malignant neoplasm of rectum
0.712 0.288 0.000
F99-F99 Unspecified mental disorder
0.712 0.288 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.712 0.288 0.000
F70-F79 Mental retardation
0.712 0.288 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.712 0.288 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.711 0.288 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.711 0.288 0.000
M47.84 Other spondylosis (Thoracic region)
0.711 0.288 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.711 0.288 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.711 0.288 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.711 0.289 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.710 0.290 0.000
I12 Hypertensive renal disease
0.710 0.290 0.000
E66 Obesity
0.709 0.291 0.000
E16 Other disorders of pancreatic internal secretion
0.709 0.291 0.000
I25.6 Silent myocardial ischaemia
0.708 0.292 0.000
I25.5 Ischaemic cardiomyopathy
0.708 0.292 0.000
I25.4 Coronary artery aneurysm
0.708 0.292 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.708 0.292 0.000
R57 Shock, not elsewhere classified
0.708 0.292 0.000
D10-D36 Benign neoplasms
0.708 0.292 0.000
M80-M85 Disorders of bone density and structure
0.708 0.292 0.000
R50.8 Other specified fever
0.707 0.293 0.000
R50.2 Drug-induced fever
0.707 0.293 0.000
R50.1 Persistent fever
0.707 0.293 0.000
F40.2 Specific (isolated) phobias
0.707 0.293 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.706 0.294 0.000
E04.1 Non-toxic single thyroid nodule
0.706 0.294 0.000
F38 Other mood [affective] disorders
0.703 0.297 0.000
F34 Persistent mood [affective] disorders
0.703 0.297 0.000
F39 Unspecified mood [affective] disorder
0.703 0.297 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.703 0.297 0.000
Y44 Agents primarily affecting blood constituents
0.702 0.298 0.000
R54 Senility
0.701 0.299 0.000
M25.0 Haemarthrosis
0.701 0.299 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.700 0.300 0.000
M13.9 Arthritis, unspecified
0.700 0.300 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.700 0.300 0.000
I70 Atherosclerosis
0.699 0.300 0.000
R42 Dizziness and giddiness
0.698 0.302 0.000
M72 Fibroblastic disorders
0.697 0.303 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.697 0.303 0.000
I99 Other and unspecified disorders of circulatory system
0.697 0.303 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.696 0.304 0.000
M50-M54 Other dorsopathies
0.696 0.304 0.000
M71 Other bursopathies
0.695 0.305 0.000
M65-M68 Disorders of synovium and tendon
0.695 0.305 0.000
E10.4 With neurological complications
0.694 0.306 0.000
O00-O08 Pregnancy with abortive outcome
0.694 0.306 0.000
M79.1 Myalgia
0.694 0.306 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.694 0.306 0.000
Y35-Y36 Legal intervention and operations of war
0.694 0.306 0.000
Y10-Y34 Event of undetermined intent
0.694 0.306 0.000
Y00-Y09 Assault
0.694 0.306 0.000
X85-X99 Assault
0.694 0.306 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.694 0.306 0.000
X50-X57 Overexertion, travel and privation
0.694 0.306 0.000
X30-X39 Exposure to forces of nature
0.694 0.306 0.000
X20-X29 Contact with venomous animals and plants
0.694 0.306 0.000
X10-X19 Contact with heat and hot substances
0.694 0.306 0.000
X00-X09 Exposure to smoke, fire and flames
0.694 0.306 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.694 0.306 0.000
W75-W84 Other accidental threats to breathing
0.694 0.306 0.000
W65-W74 Accidental drowning and submersion
0.694 0.306 0.000
W50-W64 Exposure to animate mechanical forces
0.694 0.306 0.000
V98-V99 Other and unspecified transport accidents
0.694 0.306 0.000
V95-V97 Air and space transport accidents
0.694 0.306 0.000
V90-V94 Water transport accidents
0.694 0.306 0.000
V70-V79 Bus occupant injured in transport accident
0.694 0.306 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.694 0.306 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.694 0.306 0.000
V40-V49 Car occupant injured in transport accident
0.694 0.306 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.694 0.306 0.000
V01-V09 Pedestrian injured in transport accident
0.694 0.306 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.693 0.307 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.693 0.307 0.000
E00 Congenital iodine-deficiency syndrome
0.693 0.307 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.693 0.307 0.000
I11 Hypertensive heart disease
0.692 0.308 0.000
D00-D09 In situ neoplasms
0.692 0.308 0.000
T87 Complications peculiar to reattachment and amputation
0.691 0.309 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.689 0.311 0.000
R63.5 Abnormal weight gain
0.689 0.311 0.000
R63.3 Feeding difficulties and mismanagement
0.689 0.311 0.000
R63.2 Polyphagia
0.689 0.311 0.000
R63.1 Polydipsia
0.689 0.311 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.689 0.311 0.000
I22.8 Subsequent myocardial infarction of other sites
0.688 0.312 0.000
I44 Atrioventricular and left bundle-branch block
0.688 0.312 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.688 0.312 0.000
I15 Secondary hypertension
0.687 0.313 0.000
I13 Hypertensive heart and renal disease
0.687 0.313 0.000
F31.8 Other bipolar affective disorders
0.687 0.313 0.000
F31.7 Bipolar affective disorder, currently in remission
0.687 0.313 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.687 0.313 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.687 0.313 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.687 0.313 0.000
F80-F89 Disorders of psychological development
0.686 0.314 0.000
M25.8 Other specified joint disorders
0.685 0.315 0.000
T33-T35 Frostbite
0.685 0.315 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.685 0.315 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.685 0.315 0.000
T00-T07 Injuries involving multiple body regions
0.685 0.315 0.000
S10-S19 Injuries to the neck
0.685 0.315 0.000
M47.2 Other spondylosis with radiculopathy
0.684 0.316 0.000
I95.8 Other hypotension
0.683 0.317 0.000
I95.0 Idiopathic hypotension
0.683 0.317 0.000
D12.2 Ascending colon
0.682 0.318 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.681 0.319 0.000
E07 Other disorders of thyroid
0.681 0.319 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.680 0.320 0.000
E61 Deficiency of other nutrient elements
0.680 0.320 0.000
I72.8 Aneurysm of other specified arteries
0.679 0.320 0.000
S00-S09 Injuries to the head
0.678 0.322 0.000
S70-S79 Injuries to the hip and thigh
0.677 0.323 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.677 0.323 0.000
M76 Enthesopathies of lower limb, excluding foot
0.677 0.323 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.677 0.323 0.000
E14.8 With unspecified complications
0.675 0.324 0.000
E14.7 With multiple complications
0.675 0.324 0.000
E14.6 With other specified complications
0.675 0.324 0.000
E14.5 With peripheral circulatory complications
0.675 0.324 0.000
E14.4 With neurological complications
0.675 0.324 0.000
E14.2 Withrenal complications
0.675 0.324 0.000
E14.1 With ketoacidosis
0.675 0.324 0.000
E14.0 With coma
0.675 0.324 0.000
K76 Other diseases of liver
0.675 0.325 0.000
M77 Other enthesopathies
0.675 0.325 0.000
S20-S29 Injuries to the thorax
0.674 0.326 0.000
I47 Paroxysmal tachycardia
0.673 0.327 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.673 0.327 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.673 0.327 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.673 0.327 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.673 0.327 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.673 0.327 0.000
T36 Poisoning by systemic antibiotics
0.673 0.327 0.000
R68 Other general symptoms and signs
0.673 0.327 0.000
T46.1 Calcium-channel blockers
0.673 0.327 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.672 0.328 0.000
W00-W19 Falls
0.672 0.328 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.671 0.329 0.000
E06 Thyroiditis
0.671 0.329 0.000
Y45.2 Propionic acid derivatives
0.670 0.330 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.669 0.331 0.000
E10.8 With unspecified complications
0.668 0.332 0.000
E10.7 With multiple complications
0.668 0.332 0.000
E10.6 With other specified complications
0.668 0.332 0.000
E10.5 With peripheral circulatory complications
0.668 0.332 0.000
E10.2 With renal complications
0.668 0.332 0.000
E10.0 With coma
0.668 0.332 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.667 0.332 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.667 0.333 0.000
E14.3 With ophthalmic complications
0.666 0.333 0.000
M45 Ankylosing spondylitis
0.665 0.335 0.000
F48 Other neurotic disorders
0.664 0.336 0.000
F44 Dissociative [conversion] disorders
0.664 0.336 0.000
F42 Obsessive-compulsive disorder
0.664 0.336 0.000
W20-W49 Exposure to inanimate mechanical forces
0.664 0.336 0.000
T85.2 Mechanical complication of intraocular lens
0.663 0.337 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.663 0.337 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.662 0.338 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.662 0.338 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.662 0.338 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.662 0.338 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.662 0.338 0.000
Y45.0 Opioids and related analgesics
0.661 0.339 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.660 0.340 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.659 0.341 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.659 0.341 0.000
M34 Systemic sclerosis
0.659 0.341 0.000
M33 Dermatopolymyositis
0.659 0.341 0.000
M32 Systemic lupus erythematosus
0.659 0.341 0.000
M30 Polyarteritis nodosa and related conditions
0.659 0.341 0.000
M24.1 Other articular cartilage disorders
0.658 0.342 0.000
M79.0 Rheumatism, unspecified
0.658 0.342 0.000
F30.2 Mania with psychotic symptoms
0.657 0.343 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.657 0.343 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.656 0.344 0.000
M13.94 Arthritis, unspecified (Hand)
0.656 0.344 0.000
R56 Convulsions, not elsewhere classified
0.656 0.344 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.656 0.344 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.655 0.345 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.655 0.345 0.000
Y59 Other and unspecified vaccines and biological substances
0.654 0.346 0.000
Y58 Bacterial vaccines
0.654 0.346 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.654 0.346 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.654 0.346 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.654 0.346 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.654 0.346 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.654 0.346 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.654 0.346 0.000
Y48 Anaesthetics and therapeutic gases
0.654 0.346 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.654 0.346 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.654 0.346 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.654 0.346 0.000
T86 Failure and rejection of transplanted organs and tissues
0.653 0.347 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.652 0.348 0.000
M21 Other acquired deformities of limbs
0.649 0.350 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.649 0.350 0.000
I20.1 Angina pectoris with documented spasm
0.648 0.352 0.000
I77.8 Other specified disorders of arteries and arterioles
0.647 0.352 0.000
I77.5 Necrosis of artery
0.647 0.352 0.000
I77.4 Coeliac artery compression syndrome
0.647 0.352 0.000
I77.3 Arterial fibromuscular dysplasia
0.647 0.352 0.000
I77.2 Rupture of artery
0.647 0.352 0.000
I77.0 Arteriovenous fistula, acquired
0.647 0.352 0.000
M25.9 Joint disorder, unspecified
0.645 0.354 0.000
M25.2 Flail joint
0.645 0.354 0.000
M25.1 Fistula of joint
0.645 0.354 0.000
M25.53 Pain in joint (Forearm)
0.645 0.355 0.000
O66 Other obstructed labour
0.645 0.355 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.645 0.355 0.000
Y43 Primarily systemic agents
0.644 0.355 0.000
Chapter VI Diseases of the nervous system
0.644 0.356 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.644 0.356 0.000
I72.9 Aneurysm of unspecified site
0.644 0.356 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.644 0.356 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.644 0.356 0.000
I72.3 Aneurysm of iliac artery
0.644 0.356 0.000
I72.2 Aneurysm of renal artery
0.644 0.356 0.000
I72.1 Aneurysm of artery of upper extremity
0.644 0.356 0.000
I72.0 Aneurysm of carotid artery
0.644 0.356 0.000
M87 Osteonecrosis
0.643 0.357 0.000
T79-T79 Certain early complications of trauma
0.642 0.358 0.000
R52.0 Acute pain
0.642 0.358 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.642 0.358 0.000
F60 Specific personality disorders
0.642 0.358 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.641 0.359 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.641 0.359 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.641 0.359 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.640 0.360 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.640 0.360 0.000
R00 Abnormalities of heart beat
0.639 0.361 0.000
M25.58 Pain in joint (Other)
0.639 0.361 0.000
M25.52 Pain in joint (Upper arm)
0.639 0.361 0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic
0.638 0.362 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.638 0.362 0.000
E05.8 Other thyrotoxicosis
0.637 0.363 0.000
E05.5 Thyroid crisis or storm
0.637 0.363 0.000
E05.4 Thyrotoxicosis factitia
0.637 0.363 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.637 0.363 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.637 0.363 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.637 0.363 0.000
M94 Other disorders of cartilage
0.635 0.365 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.635 0.365 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.634 0.366 0.000
S40-S49 Injuries to the shoulder and upper arm
0.633 0.367 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.631 0.369 0.000
K75 Other inflammatory liver diseases
0.631 0.369 0.000
I63 Cerebral infarction
0.631 0.369 0.000
D12.3 Transverse colon
0.630 0.370 0.000
M75.0 Adhesive capsulitis of shoulder
0.630 0.370 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.630 0.370 0.000
I74.5 Embolism and thrombosis of iliac artery
0.630 0.370 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.629 0.371 0.000
K92 Other diseases of digestive system
0.628 0.372 0.000
D03 Melanoma in situ
0.628 0.372 0.000
M07 Psoriatic and enteropathic arthropathies
0.627 0.373 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.626 0.374 0.000
K08 Other disorders of teeth and supporting structures
0.625 0.375 0.000
I20.9 Angina pectoris, unspecified
0.625 0.375 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.625 0.375 0.000
M75.9 Shoulder lesion, unspecified
0.624 0.376 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.624 0.376 0.000
M43 Other deforming dorsopathies
0.623 0.377 0.000
F00 Dementia in Alzheimer's disease
0.623 0.377 0.000
E16.2 Hypoglycaemia, unspecified
0.621 0.378 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.621 0.379 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.621 0.379 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.620 0.380 0.000
Y45.1 Salicylates
0.620 0.380 0.000
I21 Acute myocardial infarction
0.620 0.380 0.000
F41.1 Generalised anxiety disorder
0.619 0.381 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.619 0.381 0.000
R25 Abnormal involuntary movements
0.618 0.382 0.000
M51 Other intervertebral disk disorders
0.618 0.382 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.617 0.383 0.000
T66-T78 Other and unspecified effects of external causes
0.615 0.385 0.000
M79.7 Fibromyalgia
0.614 0.386 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.614 0.386 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.613 0.387 0.000
E03.8 Other specified hypothyroidism
0.612 0.387 0.000
E03.5 Myxoedema coma
0.612 0.387 0.000
E03.4 Atrophy of thyroid (acquired)
0.612 0.387 0.000
E03.3 Postinfectious hypothyroidism
0.612 0.387 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.612 0.387 0.000
E03.1 Congenital hypothyroidism without goitre
0.612 0.387 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.612 0.387 0.000
I78.1 Naevus, nonneoplastic
0.611 0.389 0.000
M22 Disorders of patella
0.611 0.389 0.000
I47.2 Ventricular tachycardia
0.610 0.390 0.000
I35 Nonrheumatic aortic valve disorders
0.610 0.390 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.609 0.390 0.000
Y95 Nosocomial condition
0.608 0.392 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.608 0.392 0.000
M48.0 Spinal stenosis
0.608 0.392 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.608 0.392 0.000
O40 Polyhydramnios
0.608 0.392 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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