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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs80095409
log Bayes Factor = 23.6243
Chromosome 7   position 107,600,211  (GRCh37) Explore rs80095409 on Ensembl!
Variant rs80095409 is part of Cluster X0277

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
J09-J18 Influenza and pneumonia
0.999 0.001 0.000
J40-J47 Chronic lower respiratory diseases
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
Chapter I Certain infectious and parasitic diseases
0.998 0.002 0.000
J18 Pneumonia, organism unspecified
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.997 0.003 0.000
I21 Acute myocardial infarction
0.997 0.003 0.000
J18.1 Lobar pneumonia, unspecified
0.995 0.005 0.000
E70-E90 Metabolic disorders
0.995 0.005 0.000
I25 Chronic ischaemic heart disease
0.995 0.005 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.994 0.006 0.000
M70-M79 Other soft tissue disorders
0.990 0.010 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.990 0.010 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.989 0.011 0.000
M79.6 Pain in limb
0.989 0.011 0.000
I25.1 Atherosclerotic heart disease
0.985 0.015 0.000
J43 Emphysema
0.980 0.020 0.000
Chapter VI Diseases of the nervous system
0.979 0.021 0.000
J44 Other chronic obstructive pulmonary disease
0.978 0.022 0.000
E00-E07 Disorders of thyroid gland
0.976 0.024 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.973 0.027 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.973 0.027 0.000
A00-A09 Intestinal infectious diseases
0.969 0.031 0.000
J43.9 Emphysema, unspecified
0.967 0.033 0.000
J30-J39 Other diseases of upper respiratory tract
0.965 0.035 0.000
F30-F39 Mood [affective] disorders
0.965 0.035 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.961 0.039 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.952 0.048 0.000
E86 Volume depletion
0.949 0.051 0.000
M79.66 Pain in limb (Lower leg)
0.949 0.051 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.943 0.057 0.000
I44 Atrioventricular and left bundle-branch block
0.939 0.061 0.000
I50 Heart failure
0.937 0.063 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.934 0.066 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.929 0.071 0.000
F32 Depressive episode
0.928 0.072 0.000
G40-G47 Episodic and paroxysmal disorders
0.925 0.075 0.000
J18.9 Pneumonia, unspecified
0.925 0.075 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.923 0.077 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.922 0.078 0.000
E20-E35 Disorders of other endocrine glands
0.921 0.079 0.000
J95-J99 Other diseases of the respiratory system
0.920 0.080 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.919 0.081 0.000
E03 Other hypothyroidism
0.919 0.081 0.000
I51 Complications and ill-defined descriptions of heart disease
0.919 0.081 0.000
A30-A49 Other bacterial diseases
0.917 0.083 0.000
M45-M49 Spondylopathies
0.917 0.083 0.000
C34 Malignant neoplasm of bronchus and lung
0.917 0.083 0.000
F17.1 Harmful use
0.916 0.084 0.000
I20 Angina pectoris
0.915 0.085 0.000
I21.9 Acute myocardial infarction, unspecified
0.914 0.086 0.000
I44.7 Left bundle-branch block, unspecified
0.912 0.088 0.000
M79.67 Pain in limb (Ankle and foot)
0.907 0.093 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.902 0.098 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.901 0.099 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.897 0.103 0.000
M50-M54 Other dorsopathies
0.896 0.104 0.000
C79 Secondary malignant neoplasm of other sites
0.896 0.104 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.888 0.112 0.000
T66-T78 Other and unspecified effects of external causes
0.886 0.114 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.882 0.118 0.000
C34.1 Upper lobe, bronchus or lung
0.879 0.121 0.000
E03.9 Hypothyroidism, unspecified
0.878 0.122 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.878 0.122 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.877 0.123 0.000
J39 Other diseases of upper respiratory tract
0.877 0.123 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.877 0.123 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.876 0.124 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.876 0.124 0.000
J32 Chronic sinusitis
0.874 0.126 0.000
A04 Other bacterial intestinal infections
0.872 0.128 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.871 0.129 0.000
I21.4 Acute subendocardial myocardial infarction
0.870 0.130 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.869 0.131 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.868 0.132 0.000
D10-D36 Benign neoplasms
0.865 0.135 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.863 0.137 0.000
G47 Sleep disorders
0.862 0.138 0.000
I51.8 Other ill-defined heart diseases
0.859 0.141 0.000
S50-S59 Injuries to the elbow and forearm
0.857 0.143 0.000
M79.8 Other specified soft tissue disorders
0.854 0.146 0.000
B35-B49 Mycoses
0.852 0.148 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.852 0.148 0.000
S20-S29 Injuries to the thorax
0.850 0.150 0.000
A41 Other septicaemia
0.847 0.153 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.847 0.153 0.000
M47 Spondylosis
0.847 0.153 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.846 0.154 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.840 0.160 0.000
J98 Other respiratory disorders
0.839 0.161 0.000
I49 Other cardiac arrhythmias
0.838 0.161 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.836 0.164 0.000
C64-C68 Malignant neoplasms of urinary tract
0.836 0.164 0.000
E83 Disorders of mineral metabolism
0.835 0.165 0.000
J90-J94 Other diseases of pleura
0.834 0.166 0.000
Chapter XX External causes of morbidity and mortality
0.832 0.168 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.830 0.170 0.000
I20.0 Unstable angina
0.830 0.170 0.000
I50.0 Congestive heart failure
0.829 0.171 0.000
E10-E14 Diabetes mellitus
0.826 0.174 0.000
C60-C63 Malignant neoplasms of male genital organs
0.825 0.175 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.821 0.179 0.000
F60-F69 Disorders of adult personality and behaviour
0.820 0.180 0.000
J30 Vasomotor and allergic rhinitis
0.815 0.185 0.000
A04.8 Other specified bacterial intestinal infections
0.813 0.187 0.000
J40 Bronchitis, not specified as acute or chronic
0.813 0.187 0.000
M54 Dorsalgia
0.812 0.188 0.000
F31 Bipolar affective disorder
0.811 0.189 0.000
D27 Benign neoplasm of ovary
0.810 0.190 0.000
I50.1 Left ventricular failure
0.810 0.190 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.808 0.192 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.808 0.192 0.000
D00-D09 In situ neoplasms
0.808 0.192 0.000
D47.1 Chronic myeloproliferative disease
0.807 0.193 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.806 0.194 0.000
T78 Adverse effects, not elsewhere classified
0.806 0.194 0.000
S70-S79 Injuries to the hip and thigh
0.805 0.195 0.000
M79.63 Pain in limb (Forearm)
0.805 0.195 0.000
I45 Other conduction disorders
0.804 0.196 0.000
F32.9 Depressive episode, unspecified
0.802 0.198 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.802 0.198 0.000
B95-B98 Bacterial, viral and other infectious agents
0.802 0.198 0.000
C80 Malignant neoplasm without specification of site
0.800 0.200 0.000
E05.9 Thyrotoxicosis, unspecified
0.797 0.203 0.000
E78.5 Hyperlipidaemia, unspecified
0.796 0.204 0.000
M47.8 Other spondylosis
0.795 0.205 0.000
I95 Hypotension
0.790 0.210 0.000
M79.60 Pain in limb (Multiple sites)
0.789 0.211 0.000
J20-J22 Other acute lower respiratory infections
0.788 0.212 0.000
J47 Bronchiectasis
0.788 0.212 0.000
S90-S99 Injuries to the ankle and foot
0.787 0.213 0.000
J39.2 Other diseases of pharynx
0.786 0.214 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.786 0.214 0.000
C77.1 Intrathoracic lymph nodes
0.785 0.215 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.784 0.216 0.000
M79.69 Pain in limb (Site unspecified)
0.780 0.220 0.000
J32.0 Chronic maxillary sinusitis
0.779 0.221 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.779 0.221 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.777 0.223 0.000
G47.3 Sleep apnoea
0.777 0.223 0.000
S80-S89 Injuries to the knee and lower leg
0.776 0.223 0.000
M71 Other bursopathies
0.774 0.226 0.000
F80-F89 Disorders of psychological development
0.774 0.226 0.000
T79-T79 Certain early complications of trauma
0.774 0.226 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.773 0.227 0.000
G70-G73 Diseases of myoneural junction and muscle
0.771 0.229 0.000
I47 Paroxysmal tachycardia
0.769 0.231 0.000
M47.82 Other spondylosis (Cervical region)
0.768 0.232 0.000
C79.2 Secondary malignant neoplasm of skin
0.767 0.233 0.000
I22 Subsequent myocardial infarction
0.766 0.234 0.000
I25.5 Ischaemic cardiomyopathy
0.766 0.234 0.000
J11 Influenza, virus not identified
0.765 0.235 0.000
Chapter VII Diseases of the eye and adnexa
0.763 0.237 0.000
J98.4 Other disorders of lung
0.759 0.241 0.000
D45 Polycythaemia vera
0.757 0.242 0.000
S40-S49 Injuries to the shoulder and upper arm
0.756 0.243 0.000
E14 Unspecified diabetes mellitus
0.756 0.244 0.000
M86-M90 Other osteopathies
0.755 0.245 0.000
G62 Other polyneuropathies
0.754 0.246 0.000
Chapter XXII Codes for special purposes
0.752 0.248 0.000
M77 Other enthesopathies
0.751 0.249 0.000
B07 Viral warts
0.751 0.249 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.750 0.250 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.749 0.251 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.749 0.251 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.748 0.252 0.000
B37 Candidiasis
0.748 0.252 0.000
F20 Schizophrenia
0.748 0.252 0.000
I42 Cardiomyopathy
0.747 0.253 0.000
S52 Fracture of forearm
0.747 0.253 0.000
M79.5 Residual foreign body in soft tissue
0.747 0.253 0.000
T82.1 Mechanical complication of cardiac electronic device
0.746 0.254 0.000
F99-F99 Unspecified mental disorder
0.745 0.255 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.745 0.255 0.000
M54.5 Low back pain
0.745 0.255 0.000
E04 Other non-toxic goitre
0.745 0.255 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.743 0.257 0.000
F41 Other anxiety disorders
0.743 0.257 0.000
D32 Benign neoplasm of meninges
0.741 0.259 0.000
E50-E64 Other nutritional deficiencies
0.740 0.260 0.000
E78.0 Pure hypercholesterolaemia
0.740 0.260 0.000
I49.9 Cardiac arrhythmia, unspecified
0.738 0.262 0.000
I24 Other acute ischaemic heart diseases
0.738 0.262 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.738 0.262 0.000
I20.9 Angina pectoris, unspecified
0.737 0.263 0.000
E83.5 Disorders of calcium metabolism
0.736 0.264 0.000
Chapter VIII Diseases of the ear and mastoid process
0.734 0.266 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.733 0.267 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.733 0.267 0.000
E87.7 Fluid overload
0.731 0.269 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.731 0.269 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.730 0.270 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.730 0.270 0.000
D22 Melanocytic naevi
0.728 0.272 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.728 0.272 0.000
C34.3 Lower lobe, bronchus or lung
0.726 0.274 0.000
C77.0 Lymph nodes of head, face and neck
0.726 0.274 0.000
M80-M85 Disorders of bone density and structure
0.725 0.274 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.724 0.276 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.723 0.277 0.000
I95.1 Orthostatic hypotension
0.722 0.278 0.000
I34 Nonrheumatic mitral valve disorders
0.721 0.279 0.000
I51.9 Heart disease, unspecified
0.721 0.279 0.000
T78.4 Allergy, unspecified
0.720 0.280 0.000
I50.9 Heart failure, unspecified
0.719 0.281 0.000
E87.5 Hyperkalaemia
0.719 0.281 0.000
C78.7 Secondary malignant neoplasm of liver
0.719 0.281 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.717 0.283 0.000
E21.0 Primary hyperparathyroidism
0.716 0.284 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.716 0.284 0.000
J17 Pneumonia in diseases classified elsewhere
0.716 0.284 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.716 0.284 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.716 0.284 0.000
J12 Viral pneumonia, not elsewhere classified
0.716 0.284 0.000
J10 Influenza due to identified influenza virus
0.716 0.284 0.000
J14 Pneumonia due to Haemophilus influenzae
0.716 0.284 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.716 0.284 0.000
J09 Influenza due to certain identified influenza virus
0.716 0.284 0.000
J41 Simple and mucopurulent chronic bronchitis
0.716 0.284 0.000
J46 Status asthmaticus
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
B99-B99 Other infectious diseases
0.716 0.284 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B65-B83 Helminthiases
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.716 0.284 0.000
B15-B19 Viral hepatitis
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A80-A89 Viral infections of the central nervous system
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
I25.2 Old myocardial infarction
0.716 0.284 0.000
J18.8 Other pneumonia, organism unspecified
0.715 0.284 0.000
J18.2 Hypostatic pneumonia, unspecified
0.715 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.715 0.285 0.000
I48 Atrial fibrillation and flutter
0.715 0.285 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.715 0.285 0.000
I41 Myocarditis in diseases classified elsewhere
0.715 0.285 0.000
I40 Acute myocarditis
0.715 0.285 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.715 0.285 0.000
I37 Pulmonary valve disorders
0.715 0.285 0.000
I36 Nonrheumatic tricuspid valve disorders
0.715 0.285 0.000
I33 Acute and subacute endocarditis
0.715 0.285 0.000
I32 Pericarditis in diseases classified elsewhere
0.715 0.285 0.000
I30 Acute pericarditis
0.715 0.285 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.715 0.285 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.715 0.285 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.715 0.285 0.000
E88 Other metabolic disorders
0.714 0.286 0.000
E85 Amyloidosis
0.714 0.286 0.000
E84 Cystic fibrosis
0.714 0.286 0.000
E79 Disorders of purine and pyrimidine metabolism
0.714 0.286 0.000
E77 Disorders of glycoprotein metabolism
0.714 0.286 0.000
E76 Disorders of glycosaminoglycan metabolism
0.714 0.286 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.714 0.286 0.000
E74 Other disorders of carbohydrate metabolism
0.714 0.286 0.000
E73 Lactose intolerance
0.714 0.286 0.000
E72 Other disorders of amino-acid metabolism
0.714 0.286 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.714 0.286 0.000
E70 Disorders of aromatic amino-acid metabolism
0.714 0.286 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.714 0.286 0.000
I25.6 Silent myocardial ischaemia
0.713 0.287 0.000
I25.4 Coronary artery aneurysm
0.713 0.287 0.000
I25.3 Aneurysm of heart
0.713 0.287 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.713 0.287 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.713 0.287 0.000
M91-M94 Chondropathies
0.712 0.287 0.000
M60-M63 Disorders of muscles
0.712 0.287 0.000
M00-M03 Infectious arthropathies
0.712 0.287 0.000
F17.2 Dependence syndrome
0.712 0.288 0.000
F03 Unspecified dementia
0.712 0.288 0.000
T86 Failure and rejection of transplanted organs and tissues
0.712 0.288 0.000
G90-G99 Other disorders of the nervous system
0.711 0.289 0.000
A41.8 Other specified septicaemia
0.711 0.289 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.711 0.289 0.000
E23 Hypofunction and other disorders of pituitary gland
0.711 0.289 0.000
B25-B34 Other viral diseases
0.710 0.290 0.000
M76 Enthesopathies of lower limb, excluding foot
0.710 0.290 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.710 0.290 0.000
M79.7 Fibromyalgia
0.710 0.290 0.000
M79.9 Soft tissue disorder, unspecified
0.710 0.290 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.710 0.290 0.000
M79.3 Panniculitis, unspecified
0.710 0.290 0.000
M79.2 Neuralgia and neuritis, unspecified
0.710 0.290 0.000
M79.1 Myalgia
0.710 0.290 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.709 0.291 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.709 0.291 0.000
M79.68 Pain in limb (Other)
0.709 0.291 0.000
M79.64 Pain in limb (Hand)
0.709 0.291 0.000
M79.61 Pain in limb (Shoulder region)
0.709 0.291 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.708 0.292 0.000
C61 Malignant neoplasm of prostate
0.707 0.293 0.000
J30.1 Allergic rhinitis due to pollen
0.707 0.293 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.706 0.293 0.000
J39.8 Other specified diseases of upper respiratory tract
0.706 0.294 0.000
J42 Unspecified chronic bronchitis
0.706 0.294 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.705 0.295 0.000
J32.9 Chronic sinusitis, unspecified
0.705 0.295 0.000
C83.3 Large cell (diffuse)
0.704 0.296 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.704 0.296 0.000
A49 Bacterial infection of unspecified site
0.703 0.297 0.000
D23 Other benign neoplasms of skin
0.703 0.297 0.000
J43.8 Other emphysema
0.703 0.297 0.000
J43.2 Centrilobular emphysema
0.703 0.297 0.000
J43.1 Panlobular emphysema
0.703 0.297 0.000
J43.0 MacLeod's syndrome
0.703 0.297 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.702 0.298 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.702 0.298 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.701 0.299 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.701 0.299 0.000
F31.9 Bipolar affective disorder, unspecified
0.701 0.299 0.000
J35 Chronic diseases of tonsils and adenoids
0.700 0.300 0.000
J18.0 Bronchopneumonia, unspecified
0.700 0.300 0.000
E06 Thyroiditis
0.700 0.300 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.700 0.300 0.000
E00 Congenital iodine-deficiency syndrome
0.700 0.300 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.700 0.300 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.699 0.300 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.699 0.301 0.000
E28 Ovarian dysfunction
0.699 0.301 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.699 0.301 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.698 0.302 0.000
I38 Endocarditis, valve unspecified
0.697 0.303 0.000
M48 Other spondylopathies
0.697 0.303 0.000
C77.5 Intrapelvic lymph nodes
0.697 0.303 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.696 0.304 0.000
E07 Other disorders of thyroid
0.695 0.304 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.695 0.305 0.000
A04.5 Campylobacter enteritis
0.695 0.305 0.000
A07 Other protozoal intestinal diseases
0.695 0.305 0.000
A06 Amoebiasis
0.695 0.305 0.000
A05 Other bacterial foodborne intoxications
0.695 0.305 0.000
A03 Shigellosis
0.695 0.305 0.000
A02 Other Salmonella infections
0.695 0.305 0.000
A01 Typhoid and paratyphoid fevers
0.695 0.305 0.000
A00 Cholera
0.695 0.305 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.694 0.306 0.000
I44.2 Atrioventricular block, complete
0.694 0.306 0.000
J37 Chronic laryngitis and laryngotracheitis
0.692 0.308 0.000
J36 Peritonsillar abscess
0.692 0.308 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.692 0.308 0.000
F38 Other mood [affective] disorders
0.692 0.308 0.000
F34 Persistent mood [affective] disorders
0.692 0.308 0.000
F30 Manic episode
0.692 0.308 0.000
F39 Unspecified mood [affective] disorder
0.692 0.308 0.000
F60 Specific personality disorders
0.691 0.309 0.000
G30-G32 Other degenerative diseases of the nervous system
0.690 0.310 0.000
Y95 Nosocomial condition
0.690 0.310 0.000
S60-S69 Injuries to the wrist and hand
0.690 0.310 0.000
C34.9 Bronchus or lung, unspecified
0.690 0.310 0.000
W20-W49 Exposure to inanimate mechanical forces
0.690 0.310 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.689 0.311 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.689 0.311 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.689 0.311 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.689 0.311 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.689 0.311 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.689 0.311 0.000
T81 Complications of procedures, not elsewhere classified
0.689 0.311 0.000
C78.2 Secondary malignant neoplasm of pleura
0.688 0.312 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.686 0.314 0.000
G35 Multiple sclerosis
0.686 0.314 0.000
C67 Malignant neoplasm of bladder
0.685 0.315 0.000
C92 Myeloid leukaemia
0.684 0.316 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.682 0.318 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.682 0.318 0.000
C32 Malignant neoplasm of larynx
0.682 0.318 0.000
C31 Malignant neoplasm of accessory sinuses
0.682 0.318 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.682 0.318 0.000
C37 Malignant neoplasm of thymus
0.682 0.318 0.000
C33 Malignant neoplasm of trachea
0.682 0.318 0.000
D41.4 Bladder
0.682 0.318 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.680 0.320 0.000
J98.8 Other specified respiratory disorders
0.680 0.320 0.000
M46 Other inflammatory spondylopathies
0.680 0.320 0.000
G45.3 Amaurosis fugax
0.679 0.321 0.000
G45.4 Transient global amnesia
0.679 0.321 0.000
Q60-Q64 Congenital malformations of the urinary system
0.678 0.322 0.000
J60-J70 Lung diseases due to external agents
0.678 0.322 0.000
E14.9 Without complications
0.677 0.323 0.000
B02 Zoster [herpes zoster]
0.677 0.323 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.676 0.324 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.676 0.324 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.676 0.324 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.676 0.324 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.676 0.324 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.676 0.324 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.676 0.324 0.000
F11 Mental and behavioural disorders due to use of opioids
0.676 0.324 0.000
I45.1 Other and unspecified right bundle-branch block
0.675 0.325 0.000
F41.9 Anxiety disorder, unspecified
0.674 0.326 0.000
I44.6 Other and unspecified fascicular block
0.673 0.327 0.000
I44.5 Left posterior fascicular block
0.673 0.327 0.000
I44.4 Left anterior fascicular block
0.673 0.327 0.000
I44.3 Other and unspecified atrioventricular block
0.673 0.327 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.673 0.327 0.000
G62.9 Polyneuropathy, unspecified
0.673 0.327 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.672 0.327 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.672 0.328 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.671 0.329 0.000
J90 Pleural effusion, not elsewhere classified
0.670 0.330 0.000
F22 Persistent delusional disorders
0.670 0.330 0.000
F29 Unspecified nonorganic psychosis
0.669 0.331 0.000
M79.62 Pain in limb (Upper arm)
0.669 0.331 0.000
D46 Myelodysplastic syndromes
0.668 0.332 0.000
M79.0 Rheumatism, unspecified
0.668 0.332 0.000
D18 Haemangioma and lymphangioma, any site
0.668 0.332 0.000
S32 Fracture of lumbar spine and pelvis
0.668 0.332 0.000
S72 Fracture of femur
0.667 0.333 0.000
M50 Cervical disk disorders
0.666 0.334 0.000
F17.9 Unspecified mental and behavioural disorder
0.666 0.334 0.000
F17.8 Other mental and behavioural disorders
0.666 0.334 0.000
F17.7 Residual and late-onset psychotic disorder
0.666 0.334 0.000
F17.6 Amnesic syndrome
0.666 0.334 0.000
F17.5 Psychotic disorder
0.666 0.334 0.000
F17.4 Withdrawal state with delirium
0.666 0.334 0.000
F17.3 Withdrawal state
0.666 0.334 0.000
F17.0 Acute intoxication
0.666 0.334 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.666 0.334 0.000
F32.8 Other depressive episodes
0.665 0.335 0.000
F32.1 Moderate depressive episode
0.665 0.335 0.000
F32.0 Mild depressive episode
0.665 0.335 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.665 0.335 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.665 0.335 0.000
G44 Other headache syndromes
0.664 0.336 0.000
M53 Other dorsopathies, not elsewhere classified
0.664 0.336 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.663 0.337 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.663 0.337 0.000
G41 Status epilepticus
0.663 0.337 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.663 0.337 0.000
I49.8 Other specified cardiac arrhythmias
0.663 0.337 0.000
C91 Lymphoid leukaemia
0.662 0.338 0.000
T87 Complications peculiar to reattachment and amputation
0.662 0.338 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.662 0.338 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.661 0.339 0.000
E34 Other endocrine disorders
0.661 0.339 0.000
E32 Diseases of thymus
0.661 0.339 0.000
E31 Polyglandular dysfunction
0.661 0.339 0.000
E30 Disorders of puberty, not elsewhere classified
0.661 0.339 0.000
E29 Testicular dysfunction
0.661 0.339 0.000
E27 Other disorders of adrenal gland
0.661 0.339 0.000
E26 Hyperaldosteronism
0.661 0.339 0.000
E25 Adrenogenital disorders
0.661 0.339 0.000
E24 Cushing's syndrome
0.661 0.339 0.000
E22 Hyperfunction of pituitary gland
0.661 0.339 0.000
E20 Hypoparathyroidism
0.661 0.339 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.661 0.339 0.000
T78.3 Angioneurotic oedema
0.661 0.339 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.660 0.340 0.000
A41.9 Septicaemia, unspecified
0.660 0.340 0.000
J96 Respiratory failure, not elsewhere classified
0.659 0.341 0.000
E03.8 Other specified hypothyroidism
0.659 0.341 0.000
E03.5 Myxoedema coma
0.659 0.341 0.000
E03.4 Atrophy of thyroid (acquired)
0.659 0.341 0.000
E03.3 Postinfectious hypothyroidism
0.659 0.341 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.659 0.341 0.000
E03.1 Congenital hypothyroidism without goitre
0.659 0.341 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.659 0.341 0.000
I51.6 Cardiovascular disease, unspecified
0.659 0.341 0.000
I51.5 Myocardial degeneration
0.659 0.341 0.000
I51.4 Myocarditis, unspecified
0.659 0.341 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.659 0.341 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.659 0.341 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.659 0.341 0.000
I51.0 Cardiac septal defect, acquired
0.659 0.341 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.658 0.342 0.000
A48 Other bacterial diseases, not elsewhere classified
0.658 0.342 0.000
A44 Bartonellosis
0.658 0.342 0.000
A43 Nocardiosis
0.658 0.342 0.000
A42 Actinomycosis
0.658 0.342 0.000
A40 Streptococcal septicaemia
0.658 0.342 0.000
A39 Meningococcal infection
0.658 0.342 0.000
A37 Whooping cough
0.658 0.342 0.000
A36 Diphtheria
0.658 0.342 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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