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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs80228232
log Bayes Factor = 25.8823
Chromosome 5   position 131,388,213  (GRCh37) Explore rs80228232 on Ensembl!
Variant rs80228232 is part of Cluster X0155

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Z95 Presence of cardiac and vascular implants and grafts
1.000 0.000 0.000
N40-N51 Diseases of male genital organs
0.999 0.001 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.997 0.003 0.000
Chapter VII Diseases of the eye and adnexa
0.996 0.004 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.995 0.005 0.000
I20 Angina pectoris
0.991 0.009 0.000
N40 Hyperplasia of prostate
0.991 0.009 0.000
I25.2 Old myocardial infarction
0.985 0.015 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.978 0.022 0.000
M20-M25 Other joint disorders
0.976 0.024 0.000
I25.1 Atherosclerotic heart disease
0.975 0.025 0.000
M05-M14 Inflammatory polyarthropathies
0.974 0.026 0.000
I21 Acute myocardial infarction
0.972 0.028 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.969 0.031 0.000
N17-N19 Renal failure
0.965 0.035 0.000
Chapter X Diseases of the respiratory system
0.962 0.038 0.000
M70-M79 Other soft tissue disorders
0.959 0.041 0.000
H40-H42 Glaucoma
0.958 0.042 0.000
Chapter XX External causes of morbidity and mortality
0.957 0.043 0.000
N18 Chronic renal failure
0.950 0.050 0.000
M50-M54 Other dorsopathies
0.949 0.051 0.000
I20.0 Unstable angina
0.948 0.052 0.000
I30-I52 Other forms of heart disease
0.946 0.054 0.000
Z93 Artificial opening status
0.945 0.055 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.940 0.060 0.000
I83 Varicose veins of lower extremities
0.938 0.062 0.000
Chapter VI Diseases of the nervous system
0.936 0.064 0.000
Chapter V Mental and behavioural disorders
0.934 0.066 0.000
Z95.1 Presence of aortocoronary bypass graft
0.932 0.068 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.931 0.069 0.000
H40 Glaucoma
0.931 0.069 0.000
Chapter II Neoplasms
0.927 0.073 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.927 0.073 0.000
M13 Other arthritis
0.924 0.076 0.000
M54 Dorsalgia
0.920 0.080 0.000
Z85 Personal history of malignant neoplasm
0.918 0.082 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.918 0.082 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.917 0.083 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.909 0.091 0.000
Z95.2 Presence of prosthetic heart valve
0.908 0.092 0.000
N10-N16 Renal tubulo-interstitial diseases
0.906 0.094 0.000
I21.9 Acute myocardial infarction, unspecified
0.901 0.099 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.901 0.099 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.900 0.100 0.000
I50 Heart failure
0.900 0.100 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.898 0.102 0.000
J40-J47 Chronic lower respiratory diseases
0.897 0.103 0.000
I20.9 Angina pectoris, unspecified
0.894 0.106 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.894 0.106 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.893 0.107 0.000
J30-J39 Other diseases of upper respiratory tract
0.893 0.107 0.000
N45 Orchitis and epididymitis
0.892 0.108 0.000
M23 Internal derangement of knee
0.889 0.111 0.000
Chapter XXII Codes for special purposes
0.887 0.113 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.887 0.113 0.000
N18.3 Chronic kidney disease, stage 3
0.884 0.116 0.000
N48 Other disorders of penis
0.884 0.116 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.884 0.116 0.000
R30-R39 Symptoms and signs involving the urinary system
0.881 0.119 0.000
I24 Other acute ischaemic heart diseases
0.880 0.120 0.000
M13.9 Arthritis, unspecified
0.879 0.121 0.000
I20.8 Other forms of angina pectoris
0.878 0.122 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.868 0.132 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.867 0.133 0.000
F41 Other anxiety disorders
0.866 0.134 0.000
C44 Other malignant neoplasms of skin
0.864 0.136 0.000
J33 Nasal polyp
0.861 0.139 0.000
M15-M19 Arthrosis
0.859 0.141 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.857 0.143 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.857 0.143 0.000
M75 Shoulder lesions
0.857 0.143 0.000
R26 Abnormalities of gait and mobility
0.853 0.147 0.000
M54.5 Low back pain
0.852 0.148 0.000
I80 Phlebitis and thrombophlebitis
0.852 0.148 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.849 0.151 0.000
I81 Portal vein thrombosis
0.848 0.152 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.846 0.154 0.000
N18.9 Chronic renal failure, unspecified
0.845 0.155 0.000
H30-H36 Disorders of choroid and retina
0.844 0.156 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.843 0.157 0.000
D45 Polycythaemia vera
0.840 0.160 0.000
Z95.4 Presence of other heart-valve replacement
0.838 0.162 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.835 0.165 0.000
I84 Haemorrhoids
0.835 0.165 0.000
M80-M85 Disorders of bone density and structure
0.834 0.166 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.834 0.166 0.000
G20-G26 Extrapyramidal and movement disorders
0.833 0.166 0.000
Z95.0 Presence of cardiac pacemaker
0.831 0.169 0.000
M19 Other arthrosis
0.829 0.171 0.000
M54.9 Dorsalgia, unspecified
0.828 0.172 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.827 0.173 0.000
M35 Other systemic involvement of connective tissue
0.826 0.174 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.826 0.174 0.000
I25.5 Ischaemic cardiomyopathy
0.825 0.175 0.000
N00-N08 Glomerular diseases
0.823 0.176 0.000
Y83.3 Surgical operation with formation of external stoma
0.822 0.178 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.822 0.178 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.820 0.180 0.000
H40.1 Primary open-angle glaucoma
0.818 0.182 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.818 0.182 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.817 0.183 0.000
H40.2 Primary angle-closure glaucoma
0.817 0.183 0.000
H02 Other disorders of eyelid
0.817 0.183 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.816 0.184 0.000
N18.2 Chronic kidney disease, stage 2
0.814 0.186 0.000
J33.9 Nasal polyp, unspecified
0.814 0.186 0.000
N20-N23 Urolithiasis
0.810 0.190 0.000
R33 Retention of urine
0.810 0.190 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.808 0.192 0.000
M45-M49 Spondylopathies
0.807 0.193 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.807 0.193 0.000
I50.0 Congestive heart failure
0.806 0.194 0.000
M19.9 Arthrosis, unspecified
0.806 0.194 0.000
Z93.2 Ileostomy status
0.805 0.195 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.803 0.197 0.000
I42 Cardiomyopathy
0.802 0.198 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.802 0.198 0.000
C44.3 Skin of other and unspecified parts of face
0.802 0.198 0.000
Z83 Family history of other specific disorders
0.801 0.199 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.801 0.199 0.000
M65-M68 Disorders of synovium and tendon
0.800 0.200 0.000
M75.4 Impingement syndrome of shoulder
0.800 0.200 0.000
I22 Subsequent myocardial infarction
0.800 0.200 0.000
C44.2 Skin of ear and external auricular canal
0.800 0.200 0.000
F41.2 Mixed anxiety and depressive disorder
0.798 0.202 0.000
Z93.6 Other artificial openings of urinary tract status
0.798 0.202 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.798 0.202 0.000
N60-N64 Disorders of breast
0.797 0.203 0.000
Y83.6 Removal of other organ (partial) (total)
0.794 0.206 0.000
H43-H45 Disorders of vitreous body and globe
0.794 0.206 0.000
Z96 Presence of other functional implants
0.794 0.206 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.793 0.207 0.000
H40.9 Glaucoma, unspecified
0.793 0.207 0.000
Z86 Personal history of certain other diseases
0.792 0.208 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.788 0.212 0.000
H02.3 Blepharochalasis
0.787 0.213 0.000
I84.2 Internal haemorrhoids without complication
0.786 0.214 0.000
M20 Acquired deformities of fingers and toes
0.786 0.214 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.785 0.215 0.000
N13 Obstructive and reflux uropathy
0.783 0.217 0.000
M10 Gout
0.782 0.218 0.000
I85 Oesophageal varices
0.781 0.219 0.000
I45 Other conduction disorders
0.780 0.220 0.000
Z04 Examination and observation for other reasons
0.779 0.221 0.000
H53-H54 Visual disturbances and blindness
0.777 0.223 0.000
S60-S69 Injuries to the wrist and hand
0.777 0.223 0.000
G30-G32 Other degenerative diseases of the nervous system
0.777 0.223 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.776 0.224 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.775 0.225 0.000
M25 Other joint disorders, not elsewhere classified
0.775 0.225 0.000
Z97 Presence of other devices
0.774 0.226 0.000
Chapter I Certain infectious and parasitic diseases
0.773 0.227 0.000
Z85.6 Personal history of leukaemia
0.773 0.227 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.772 0.227 0.000
I50.1 Left ventricular failure
0.771 0.229 0.000
H35 Other retinal disorders
0.771 0.229 0.000
I87 Other disorders of veins
0.769 0.231 0.000
M75.1 Rotator cuff syndrome
0.769 0.231 0.000
M07 Psoriatic and enteropathic arthropathies
0.768 0.232 0.000
M72 Fibroblastic disorders
0.766 0.234 0.000
M86-M90 Other osteopathies
0.766 0.234 0.000
J90-J94 Other diseases of pleura
0.765 0.235 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.765 0.235 0.000
G70-G73 Diseases of myoneural junction and muscle
0.764 0.236 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.763 0.237 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.763 0.237 0.000
H10-H13 Disorders of conjunctiva
0.761 0.238 0.000
M40-M43 Deforming dorsopathies
0.761 0.239 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.761 0.239 0.000
R45 Symptoms and signs involving emotional state
0.761 0.239 0.000
C43 Malignant melanoma of skin
0.760 0.240 0.000
J47 Bronchiectasis
0.759 0.241 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.759 0.241 0.000
Chapter VIII Diseases of the ear and mastoid process
0.758 0.242 0.000
I82 Other venous embolism and thrombosis
0.756 0.243 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.756 0.244 0.000
R32 Unspecified urinary incontinence
0.754 0.246 0.000
I24.8 Other forms of acute ischaemic heart disease
0.753 0.247 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.753 0.247 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.751 0.249 0.000
R41.0 Disorientation, unspecified
0.750 0.250 0.000
M06 Other rheumatoid arthritis
0.750 0.250 0.000
S20-S29 Injuries to the thorax
0.749 0.251 0.000
U80 Agent resistant to penicillin and related antibiotics
0.749 0.251 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.749 0.251 0.000
J60-J70 Lung diseases due to external agents
0.749 0.251 0.000
Z30 Contraceptive management
0.748 0.252 0.000
Z95.3 Presence of xenogenic heart valve
0.748 0.252 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.748 0.252 0.000
S40-S49 Injuries to the shoulder and upper arm
0.743 0.257 0.000
I86 Varicose veins of other sites
0.743 0.257 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.741 0.259 0.000
J44 Other chronic obstructive pulmonary disease
0.739 0.261 0.000
N48.4 Impotence of organic origin
0.739 0.261 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.738 0.262 0.000
J35 Chronic diseases of tonsils and adenoids
0.737 0.263 0.000
M21 Other acquired deformities of limbs
0.736 0.264 0.000
N42 Other disorders of prostate
0.735 0.265 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.734 0.266 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.734 0.266 0.000
C64-C68 Malignant neoplasms of urinary tract
0.734 0.266 0.000
M35.3 Polymyalgia rheumatica
0.733 0.267 0.000
Z93.5 Cystostomy status
0.733 0.267 0.000
N20 Calculus of kidney and ureter
0.733 0.267 0.000
M24 Other specific joint derangements
0.730 0.269 0.000
F43 Reaction to severe stress, and adjustment disorders
0.730 0.270 0.000
Z96.0 Presence of urogenital implants
0.730 0.270 0.000
H40.0 Glaucoma suspect
0.729 0.271 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.729 0.271 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.727 0.273 0.000
G90-G99 Other disorders of the nervous system
0.726 0.273 0.000
L40-L45 Papulosquamous disorders
0.726 0.274 0.000
M11 Other crystal arthropathies
0.725 0.274 0.000
I21.4 Acute subendocardial myocardial infarction
0.725 0.275 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.725 0.275 0.000
J42 Unspecified chronic bronchitis
0.725 0.275 0.000
M54.56 Low back pain (Lumbar region)
0.725 0.275 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.724 0.276 0.000
N18.0 End-stage renal disease
0.724 0.276 0.000
N48.8 Other specified disorders of penis
0.722 0.278 0.000
J43 Emphysema
0.722 0.278 0.000
I46 Cardiac arrest
0.721 0.279 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.721 0.279 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.720 0.280 0.000
N10 Acute tubulo-interstitial nephritis
0.720 0.280 0.000
I50.9 Heart failure, unspecified
0.719 0.281 0.000
M54.2 Cervicalgia
0.719 0.281 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z89 Acquired absence of limb
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
T66-T78 Other and unspecified effects of external causes
0.716 0.283 0.000
M22 Disorders of patella
0.716 0.284 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.716 0.284 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.716 0.284 0.000
N46 Male infertility
0.716 0.284 0.000
N44 Torsion of testis
0.716 0.284 0.000
M13.0 Polyarthritis, unspecified
0.716 0.284 0.000
Z93.0 Tracheostomy status
0.715 0.285 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.715 0.285 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.715 0.285 0.000
M54.55 Low back pain (Thoracolumbar region)
0.715 0.285 0.000
I44 Atrioventricular and left bundle-branch block
0.715 0.285 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.715 0.285 0.000
H55-H59 Other disorders of eye and adnexa
0.714 0.286 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.714 0.286 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.713 0.287 0.000
I88 Nonspecific lymphadenitis
0.713 0.287 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.713 0.287 0.000
Z92 Personal history of medical treatment
0.713 0.287 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.712 0.288 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.712 0.288 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.711 0.288 0.000
H01 Other inflammation of eyelid
0.711 0.289 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.711 0.289 0.000
I20.1 Angina pectoris with documented spasm
0.711 0.289 0.000
I73 Other peripheral vascular diseases
0.710 0.290 0.000
H25-H28 Disorders of lens
0.710 0.290 0.000
S32 Fracture of lumbar spine and pelvis
0.709 0.291 0.000
R25 Abnormal involuntary movements
0.709 0.291 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.708 0.292 0.000
U80.1 Methicillin resistant agent
0.708 0.292 0.000
M18 Arthrosis of first carpometacarpal joint
0.707 0.293 0.000
N18.5 Chronic kidney disease, stage 5
0.706 0.294 0.000
I31 Other diseases of pericardium
0.706 0.294 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.706 0.294 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.704 0.296 0.000
J33.0 Polyp of nasal cavity
0.704 0.296 0.000
M81 Osteoporosis without pathological fracture
0.704 0.296 0.000
Y83.9 Surgical procedure, unspecified
0.703 0.296 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.703 0.297 0.000
G25 Other extrapyramidal and movement disorders
0.703 0.297 0.000
Z50 Care involving use of rehabilitation procedures
0.702 0.298 0.000
J46 Status asthmaticus
0.701 0.299 0.000
G20 Parkinson's disease
0.701 0.299 0.000
J30 Vasomotor and allergic rhinitis
0.701 0.299 0.000
Z39 Postpartum care and examination
0.700 0.300 0.000
R39 Other symptoms and signs involving the urinary system
0.700 0.300 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.700 0.300 0.000
M34 Systemic sclerosis
0.700 0.300 0.000
M33 Dermatopolymyositis
0.700 0.300 0.000
M32 Systemic lupus erythematosus
0.700 0.300 0.000
M31 Other necrotising vasculopathies
0.700 0.300 0.000
M30 Polyarteritis nodosa and related conditions
0.700 0.300 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.699 0.301 0.000
M14 Arthropathies in other diseases classified elsewhere
0.698 0.302 0.000
M12 Other specific arthropathies
0.698 0.302 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.698 0.302 0.000
M08 Juvenile arthritis
0.698 0.302 0.000
M05 Seropositive rheumatoid arthritis
0.698 0.302 0.000
L90 Atrophic disorders of skin
0.698 0.302 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.697 0.303 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.697 0.303 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.697 0.303 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.696 0.304 0.000
I49 Other cardiac arrhythmias
0.696 0.304 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.696 0.304 0.000
I51 Complications and ill-defined descriptions of heart disease
0.695 0.305 0.000
M79.8 Other specified soft tissue disorders
0.695 0.305 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.695 0.305 0.000
Z91.5 Personal history of self-harm
0.695 0.305 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.695 0.305 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.694 0.306 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.693 0.307 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.692 0.308 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.692 0.308 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.691 0.308 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.691 0.309 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.691 0.309 0.000
R00 Abnormalities of heart beat
0.690 0.310 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.690 0.310 0.000
M13.94 Arthritis, unspecified (Hand)
0.689 0.311 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.689 0.311 0.000
M77 Other enthesopathies
0.687 0.312 0.000
M76 Enthesopathies of lower limb, excluding foot
0.687 0.312 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.687 0.312 0.000
M71 Other bursopathies
0.687 0.312 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.687 0.312 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.687 0.313 0.000
H42 Glaucoma in diseases classified elsewhere
0.687 0.313 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.686 0.314 0.000
Y35-Y36 Legal intervention and operations of war
0.686 0.314 0.000
Y10-Y34 Event of undetermined intent
0.686 0.314 0.000
Y00-Y09 Assault
0.686 0.314 0.000
X85-X99 Assault
0.686 0.314 0.000
X60-X84 Intentional self-harm
0.686 0.314 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.686 0.314 0.000
X50-X57 Overexertion, travel and privation
0.686 0.314 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.686 0.314 0.000
X30-X39 Exposure to forces of nature
0.686 0.314 0.000
X20-X29 Contact with venomous animals and plants
0.686 0.314 0.000
X10-X19 Contact with heat and hot substances
0.686 0.314 0.000
X00-X09 Exposure to smoke, fire and flames
0.686 0.314 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.686 0.314 0.000
W75-W84 Other accidental threats to breathing
0.686 0.314 0.000
W65-W74 Accidental drowning and submersion
0.686 0.314 0.000
W50-W64 Exposure to animate mechanical forces
0.686 0.314 0.000
V98-V99 Other and unspecified transport accidents
0.686 0.314 0.000
V95-V97 Air and space transport accidents
0.686 0.314 0.000
V90-V94 Water transport accidents
0.686 0.314 0.000
V80-V89 Other land transport accidents
0.686 0.314 0.000
V70-V79 Bus occupant injured in transport accident
0.686 0.314 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.686 0.314 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.686 0.314 0.000
V40-V49 Car occupant injured in transport accident
0.686 0.314 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.686 0.314 0.000
V20-V29 Motorcycle rider injured in transport accident
0.686 0.314 0.000
V01-V09 Pedestrian injured in transport accident
0.686 0.314 0.000
Z35 Supervision of high-risk pregnancy
0.685 0.315 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.684 0.316 0.000
N18.8 Other chronic renal failure
0.681 0.319 0.000
N18.1 Chronic kidney disease, stage 1
0.681 0.319 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.681 0.319 0.000
M53 Other dorsopathies, not elsewhere classified
0.680 0.320 0.000
N99-N99 Other disorders of the genitourinary system
0.679 0.320 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.679 0.321 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.679 0.321 0.000
N41 Inflammatory diseases of prostate
0.679 0.321 0.000
I52 Other heart disorders in diseases classified elsewhere
0.679 0.321 0.000
I48 Atrial fibrillation and flutter
0.679 0.321 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.679 0.321 0.000
I41 Myocarditis in diseases classified elsewhere
0.679 0.321 0.000
I40 Acute myocarditis
0.679 0.321 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.679 0.321 0.000
I37 Pulmonary valve disorders
0.679 0.321 0.000
I36 Nonrheumatic tricuspid valve disorders
0.679 0.321 0.000
I33 Acute and subacute endocarditis
0.679 0.321 0.000
I32 Pericarditis in diseases classified elsewhere
0.679 0.321 0.000
I30 Acute pericarditis
0.679 0.321 0.000
R26.3 Immobility
0.678 0.322 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.678 0.322 0.000
Z86.7 Personal history of diseases of the circulatory system
0.678 0.322 0.000
Z93.9 Artificial opening status, unspecified
0.677 0.322 0.000
Z93.8 Other artificial opening status
0.677 0.322 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.677 0.323 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.677 0.323 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.676 0.324 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.676 0.324 0.000
M47 Spondylosis
0.675 0.325 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.675 0.325 0.000
S80-S89 Injuries to the knee and lower leg
0.675 0.325 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.674 0.326 0.000
Z93.3 Colostomy status
0.674 0.326 0.000
W20-W49 Exposure to inanimate mechanical forces
0.674 0.326 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.674 0.326 0.000
T79-T79 Certain early complications of trauma
0.674 0.326 0.000
T33-T35 Frostbite
0.674 0.326 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.674 0.326 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.674 0.326 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.674 0.326 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.674 0.326 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.674 0.326 0.000
T00-T07 Injuries involving multiple body regions
0.674 0.326 0.000
S10-S19 Injuries to the neck
0.674 0.326 0.000
R02 Gangrene, not elsewhere classified
0.673 0.327 0.000
M19.98 Arthrosis, unspecified (Other)
0.672 0.328 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.672 0.328 0.000
V10-V19 Pedal cyclist injured in transport accident
0.672 0.328 0.000
N43 Hydrocele and spermatocele
0.672 0.328 0.000
J33.8 Other polyp of sinus
0.671 0.329 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.671 0.329 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.671 0.329 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.671 0.329 0.000
F99-F99 Unspecified mental disorder
0.670 0.330 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.670 0.330 0.000
F80-F89 Disorders of psychological development
0.670 0.330 0.000
F70-F79 Mental retardation
0.670 0.330 0.000
F60-F69 Disorders of adult personality and behaviour
0.670 0.330 0.000
Z04.9 Examination and observation for unspecified reason
0.669 0.331 0.000
Z30.1 Insertion of (intra-uterine) contraceptive device
0.668 0.332 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.668 0.332 0.000
H40.8 Other glaucoma
0.667 0.333 0.000
H40.6 Glaucoma secondary to drugs
0.667 0.333 0.000
H40.5 Glaucoma secondary to other eye disorders
0.667 0.333 0.000
H40.4 Glaucoma secondary to eye inflammation
0.667 0.333 0.000
H40.3 Glaucoma secondary to eye trauma
0.667 0.333 0.000
N48.6 Balanitis xerotica obliterans
0.666 0.334 0.000
M51 Other intervertebral disk disorders
0.665 0.335 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.665 0.335 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.665 0.335 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.665 0.335 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.665 0.335 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.665 0.335 0.000
Z93.1 Gastrostomy status
0.664 0.336 0.000
J40 Bronchitis, not specified as acute or chronic
0.664 0.336 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.664 0.336 0.000
L91 Hypertrophic disorders of skin
0.664 0.336 0.000
S90-S99 Injuries to the ankle and foot
0.663 0.336 0.000
H35.8 Other specified retinal disorders
0.663 0.337 0.000
M13.8 Other specified arthritis
0.662 0.338 0.000
M13.1 Monoarthritis, not elsewhere classified
0.662 0.338 0.000
L60-L75 Disorders of skin appendages
0.662 0.338 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.661 0.339 0.000
R23 Other skin changes
0.661 0.339 0.000
J09-J18 Influenza and pneumonia
0.660 0.340 0.000
Z34 Supervision of normal pregnancy
0.660 0.340 0.000
M54.8 Other dorsalgia
0.660 0.340 0.000
M54.6 Pain in thoracic spine
0.660 0.340 0.000
M54.4 Lumbago with sciatica
0.660 0.340 0.000
M54.1 Radiculopathy
0.660 0.340 0.000
M54.0 Panniculitis affecting regions of neck and back
0.660 0.340 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.658 0.341 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.658 0.341 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.658 0.342 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.658 0.342 0.000
Z91.7 Personal history of female genital mutilation
0.658 0.342 0.000
Z91.6 Personal history of other physical trauma
0.658 0.342 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.658 0.342 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.658 0.342 0.000
Z91.2 Personal history of poor personal hygiene
0.658 0.342 0.000
Z94 Transplanted organ and tissue status
0.658 0.342 0.000
M23.4 Loose body in knee
0.657 0.343 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.657 0.343 0.000
N18.4 Chronic kidney disease, stage 4
0.657 0.343 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.657 0.343 0.000
N25-N29 Other disorders of kidney and ureter
0.656 0.343 0.000
N50 Other disorders of male genital organs
0.656 0.344 0.000
R21 Rash and other nonspecific skin eruption
0.656 0.344 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.655 0.345 0.000
M20.2 Hallux rigidus
0.655 0.345 0.000
I84.4 External haemorrhoids with other complications
0.654 0.346 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.654 0.346 0.000
R41.3 Other amnesia
0.652 0.348 0.000
H02.9 Disorder of eyelid, unspecified
0.652 0.348 0.000
N17 Acute renal failure
0.652 0.348 0.000
R27 Other lack of coordination
0.652 0.348 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.652 0.348 0.000
N20.1 Calculus of ureter
0.651 0.349 0.000
D46 Myelodysplastic syndromes
0.650 0.349 0.000
I45.1 Other and unspecified right bundle-branch block
0.650 0.350 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.650 0.350 0.000
I84.3 External thrombosed haemorrhoids
0.650 0.350 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.650 0.350 0.000
N15 Other renal tubulo-interstitial diseases
0.650 0.350 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.650 0.350 0.000
N11 Chronic tubulo-interstitial nephritis
0.650 0.350 0.000
Z36 Antenatal screening
0.649 0.351 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.649 0.351 0.000
F40 Phobic anxiety disorders
0.648 0.352 0.000
J95-J99 Other diseases of the respiratory system
0.647 0.352 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.648 0.352 0.000
N13.4 Hydroureter
0.647 0.353 0.000
M54.57 Low back pain (Lumbosacral region)
0.647 0.353 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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