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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs80335688
log Bayes Factor = 12.7849
Chromosome 10   position 90,949,251  (GRCh37) Explore rs80335688 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Z85 Personal history of malignant neoplasm
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
0.998 0.002 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.996 0.004 0.000
A30-A49 Other bacterial diseases
0.993 0.007 0.000
Chapter XX External causes of morbidity and mortality
0.991 0.009 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.989 0.011 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.988 0.012 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.987 0.013 0.000
Z92 Personal history of medical treatment
0.978 0.022 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.973 0.027 0.000
Z92.3 Personal history of irradiation
0.972 0.028 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.970 0.030 0.000
C77.3 Axillary and upper limb lymph nodes
0.968 0.032 0.000
A41 Other septicaemia
0.968 0.032 0.000
S00-S09 Injuries to the head
0.967 0.033 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.964 0.036 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.963 0.037 0.000
C78.7 Secondary malignant neoplasm of liver
0.959 0.041 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.954 0.046 0.000
A41.9 Septicaemia, unspecified
0.951 0.049 0.000
M05-M14 Inflammatory polyarthropathies
0.950 0.050 0.000
C34 Malignant neoplasm of bronchus and lung
0.949 0.051 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.947 0.053 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.946 0.054 0.000
Chapter VI Diseases of the nervous system
0.945 0.055 0.000
E70-E90 Metabolic disorders
0.941 0.059 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.939 0.061 0.000
A49 Bacterial infection of unspecified site
0.932 0.068 0.000
C79 Secondary malignant neoplasm of other sites
0.930 0.070 0.000
B95-B98 Bacterial, viral and other infectious agents
0.929 0.071 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.928 0.072 0.000
Y43 Primarily systemic agents
0.922 0.078 0.000
E50-E64 Other nutritional deficiencies
0.909 0.091 0.000
S90-S99 Injuries to the ankle and foot
0.909 0.091 0.000
Z95.0 Presence of cardiac pacemaker
0.908 0.092 0.000
Z90.1 Acquired absence of breast(s)
0.908 0.092 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.907 0.093 0.000
Y43.3 Other antineoplastic drugs
0.904 0.096 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.904 0.096 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.901 0.099 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.901 0.099 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.891 0.109 0.000
S00 Superficial injury of head
0.887 0.113 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.883 0.117 0.000
D00-D09 In situ neoplasms
0.880 0.120 0.000
Z97 Presence of other devices
0.879 0.121 0.000
S01 Open wound of head
0.878 0.122 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.875 0.125 0.000
T66-T78 Other and unspecified effects of external causes
0.871 0.129 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.865 0.135 0.000
Z90.2 Acquired absence of lung [part of]
0.863 0.137 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.860 0.140 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.860 0.140 0.000
M13 Other arthritis
0.860 0.140 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.860 0.140 0.000
G62 Other polyneuropathies
0.859 0.141 0.000
M06 Other rheumatoid arthritis
0.855 0.145 0.000
C64-C68 Malignant neoplasms of urinary tract
0.855 0.145 0.000
E55 Vitamin D deficiency
0.854 0.146 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.851 0.149 0.000
C34.3 Lower lobe, bronchus or lung
0.851 0.149 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.847 0.153 0.000
T81 Complications of procedures, not elsewhere classified
0.843 0.157 0.000
M07 Psoriatic and enteropathic arthropathies
0.842 0.158 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.838 0.162 0.000
C34.9 Bronchus or lung, unspecified
0.837 0.163 0.000
C78.0 Secondary malignant neoplasm of lung
0.835 0.165 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.832 0.168 0.000
A49.1 Streptococcal infection, unspecified
0.832 0.168 0.000
Chapter VIII Diseases of the ear and mastoid process
0.831 0.169 0.000
C77.5 Intrapelvic lymph nodes
0.828 0.172 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.827 0.173 0.000
M70-M79 Other soft tissue disorders
0.827 0.173 0.000
D70 Agranulocytosis
0.826 0.174 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.826 0.174 0.000
B25-B34 Other viral diseases
0.820 0.180 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.820 0.180 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.819 0.181 0.000
G90-G99 Other disorders of the nervous system
0.819 0.181 0.000
C34.1 Upper lobe, bronchus or lung
0.817 0.183 0.000
S92 Fracture of foot, except ankle
0.817 0.183 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.814 0.186 0.000
E55.9 Vitamin D deficiency, unspecified
0.814 0.186 0.000
E87.2 Acidosis
0.814 0.186 0.000
Z94 Transplanted organ and tissue status
0.810 0.190 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.809 0.191 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.808 0.192 0.000
G62.9 Polyneuropathy, unspecified
0.808 0.192 0.000
M80-M85 Disorders of bone density and structure
0.806 0.194 0.000
Z90.8 Acquired absence of other organs
0.806 0.194 0.000
G20-G26 Extrapyramidal and movement disorders
0.805 0.195 0.000
Z45 Adjustment and management of implanted device
0.805 0.195 0.000
Z97.8 Presence of other specified devices
0.803 0.197 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.803 0.197 0.000
M91-M94 Chondropathies
0.802 0.198 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.802 0.198 0.000
A46 Erysipelas
0.801 0.199 0.000
C71 Malignant neoplasm of brain
0.800 0.200 0.000
S80-S89 Injuries to the knee and lower leg
0.800 0.200 0.000
M86-M90 Other osteopathies
0.799 0.201 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.798 0.202 0.000
E86 Volume depletion
0.798 0.202 0.000
E83 Disorders of mineral metabolism
0.796 0.204 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.795 0.205 0.000
Y95 Nosocomial condition
0.791 0.209 0.000
M06.9 Rheumatoid arthritis, unspecified
0.789 0.211 0.000
R30-R39 Symptoms and signs involving the urinary system
0.789 0.211 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.788 0.212 0.000
A41.8 Other specified septicaemia
0.787 0.213 0.000
S06 Intracranial injury
0.786 0.213 0.000
C77.1 Intrathoracic lymph nodes
0.786 0.214 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.785 0.215 0.000
Z92.8 Personal history of other medical treatment
0.784 0.216 0.000
M13.9 Arthritis, unspecified
0.782 0.218 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.782 0.218 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.782 0.218 0.000
R26 Abnormalities of gait and mobility
0.780 0.220 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.779 0.221 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.778 0.222 0.000
E87.5 Hyperkalaemia
0.778 0.222 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.774 0.226 0.000
W00-W19 Falls
0.774 0.226 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.774 0.226 0.000
A49.0 Staphylococcal infection, unspecified
0.774 0.226 0.000
V40-V49 Car occupant injured in transport accident
0.773 0.227 0.000
M65-M68 Disorders of synovium and tendon
0.773 0.227 0.000
R47-R49 Symptoms and signs involving speech and voice
0.772 0.228 0.000
T39.1 4-Aminophenol derivatives
0.772 0.228 0.000
S00.9 Superficial injury of head, part unspecified
0.771 0.229 0.000
Z95.1 Presence of aortocoronary bypass graft
0.771 0.229 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.768 0.232 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.768 0.232 0.000
C77.9 Lymph node, unspecified
0.767 0.233 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.767 0.233 0.000
M07.3 Other psoriatic arthropathies
0.765 0.235 0.000
S20-S29 Injuries to the thorax
0.764 0.236 0.000
R20 Disturbances of skin sensation
0.764 0.236 0.000
C51-C58 Malignant neoplasms of female genital organs
0.763 0.237 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.762 0.238 0.000
C80 Malignant neoplasm without specification of site
0.762 0.238 0.000
E85 Amyloidosis
0.762 0.238 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.761 0.239 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.759 0.241 0.000
V20-V29 Motorcycle rider injured in transport accident
0.758 0.242 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.758 0.242 0.000
Z46 Fitting and adjustment of other devices
0.758 0.242 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.757 0.243 0.000
S01.8 Open wound of other parts of head
0.756 0.244 0.000
S60-S69 Injuries to the wrist and hand
0.753 0.247 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.752 0.248 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.752 0.248 0.000
Chapter XXII Codes for special purposes
0.750 0.250 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.749 0.251 0.000
C34.0 Main bronchus
0.748 0.252 0.000
Z45.2 Adjustment and management of vascular access device
0.748 0.252 0.000
Z95.4 Presence of other heart-valve replacement
0.747 0.253 0.000
G62.0 Drug-induced polyneuropathy
0.746 0.254 0.000
Z95.2 Presence of prosthetic heart valve
0.745 0.255 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.744 0.256 0.000
Z71.8 Other specified counselling
0.744 0.256 0.000
S00.0 Superficial injury of scalp
0.744 0.256 0.000
G93 Other disorders of brain
0.744 0.256 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.743 0.257 0.000
E10-E14 Diabetes mellitus
0.743 0.257 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.743 0.257 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.740 0.260 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.740 0.260 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.740 0.260 0.000
Z81 Family history of mental and behavioural disorders
0.739 0.260 0.000
X20-X29 Contact with venomous animals and plants
0.739 0.261 0.000
M11 Other crystal arthropathies
0.738 0.262 0.000
S01.9 Open wound of head, part unspecified
0.738 0.262 0.000
S50-S59 Injuries to the elbow and forearm
0.738 0.262 0.000
Y83.8 Other surgical procedures
0.738 0.262 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.737 0.263 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.736 0.264 0.000
S01.3 Open wound of ear
0.736 0.264 0.000
S90 Superficial injury of ankle and foot
0.734 0.266 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.733 0.267 0.000
A00-A09 Intestinal infectious diseases
0.733 0.267 0.000
Z72 Problems related to lifestyle
0.733 0.267 0.000
C77.2 Intra-abdominal lymph nodes
0.731 0.269 0.000
H90-H95 Other disorders of ear
0.731 0.269 0.000
Z89 Acquired absence of limb
0.731 0.269 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.731 0.269 0.000
D05 Carcinoma in situ of breast
0.729 0.271 0.000
R33 Retention of urine
0.728 0.272 0.000
T68 Hypothermia
0.728 0.272 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.725 0.275 0.000
S92.0 Fracture of calcaneus
0.721 0.279 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.721 0.279 0.000
R20.2 Paraesthesia of skin
0.720 0.280 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.720 0.280 0.000
E53 Deficiency of other B group vitamins
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.717 0.283 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.716 0.284 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B65-B83 Helminthiases
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.716 0.284 0.000
B15-B19 Viral hepatitis
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A80-A89 Viral infections of the central nervous system
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
A49.8 Other bacterial infections of unspecified site
0.715 0.285 0.000
C77.4 Inguinal and lower limb lymph nodes
0.715 0.285 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.713 0.287 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.713 0.287 0.000
D04 Carcinoma in situ of skin
0.713 0.287 0.000
T78 Adverse effects, not elsewhere classified
0.713 0.287 0.000
A48 Other bacterial diseases, not elsewhere classified
0.712 0.288 0.000
A44 Bartonellosis
0.712 0.288 0.000
A43 Nocardiosis
0.712 0.288 0.000
A42 Actinomycosis
0.712 0.288 0.000
A40 Streptococcal septicaemia
0.712 0.288 0.000
A39 Meningococcal infection
0.712 0.288 0.000
A37 Whooping cough
0.712 0.288 0.000
A36 Diphtheria
0.712 0.288 0.000
A32 Listeriosis
0.712 0.288 0.000
A31 Infection due to other mycobacteria
0.712 0.288 0.000
A30 Leprosy [Hansen's disease]
0.712 0.288 0.000
A38 Scarlet fever
0.712 0.288 0.000
A35 Other tetanus
0.712 0.288 0.000
A34 Obstetrical tetanus
0.712 0.288 0.000
A33 Tetanus neonatorum
0.712 0.288 0.000
M72 Fibroblastic disorders
0.712 0.288 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.712 0.288 0.000
Q80-Q89 Other congenital malformations
0.711 0.289 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.710 0.290 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.290 0.000
Y10-Y34 Event of undetermined intent
0.710 0.290 0.000
Y00-Y09 Assault
0.710 0.290 0.000
X85-X99 Assault
0.710 0.290 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.710 0.290 0.000
X50-X57 Overexertion, travel and privation
0.710 0.290 0.000
X30-X39 Exposure to forces of nature
0.710 0.290 0.000
X10-X19 Contact with heat and hot substances
0.710 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.290 0.000
W75-W84 Other accidental threats to breathing
0.710 0.290 0.000
W65-W74 Accidental drowning and submersion
0.710 0.290 0.000
W50-W64 Exposure to animate mechanical forces
0.710 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
V95-V97 Air and space transport accidents
0.710 0.290 0.000
V90-V94 Water transport accidents
0.710 0.290 0.000
V80-V89 Other land transport accidents
0.710 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.290 0.000
M05 Seropositive rheumatoid arthritis
0.710 0.290 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.709 0.291 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.709 0.291 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.709 0.291 0.000
C77.8 Lymph nodes of multiple regions
0.708 0.292 0.000
E20-E35 Disorders of other endocrine glands
0.705 0.295 0.000
W20-W49 Exposure to inanimate mechanical forces
0.703 0.297 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.703 0.297 0.000
T51 Toxic effect of alcohol
0.702 0.298 0.000
Y44 Agents primarily affecting blood constituents
0.702 0.298 0.000
T86 Failure and rejection of transplanted organs and tissues
0.701 0.298 0.000
Z92.9 Personal history of medical treatment, unspecified
0.701 0.299 0.000
Z92.5 Personal history of rehabilitation measures
0.701 0.299 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.701 0.299 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.699 0.301 0.000
D55-D59 Haemolytic anaemias
0.699 0.301 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.699 0.301 0.000
R27 Other lack of coordination
0.698 0.301 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.698 0.302 0.000
Z48 Other surgical follow-up care
0.697 0.303 0.000
C71.9 Brain, unspecified
0.697 0.303 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.696 0.304 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.696 0.304 0.000
C32 Malignant neoplasm of larynx
0.696 0.304 0.000
C31 Malignant neoplasm of accessory sinuses
0.696 0.304 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.696 0.304 0.000
C37 Malignant neoplasm of thymus
0.696 0.304 0.000
C33 Malignant neoplasm of trachea
0.696 0.304 0.000
A49.9 Bacterial infection, unspecified
0.695 0.305 0.000
E87.7 Fluid overload
0.695 0.305 0.000
A41.4 Septicaemia due to anaerobes
0.694 0.306 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.694 0.306 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.694 0.306 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.694 0.306 0.000
S08 Traumatic amputation of part of head
0.693 0.307 0.000
S07 Crushing injury of head
0.693 0.307 0.000
S05 Injury of eye and orbit
0.693 0.307 0.000
S04 Injury of cranial nerves
0.693 0.307 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.693 0.307 0.000
G30-G32 Other degenerative diseases of the nervous system
0.693 0.307 0.000
C78.2 Secondary malignant neoplasm of pleura
0.692 0.308 0.000
Z96 Presence of other functional implants
0.692 0.308 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.692 0.308 0.000
Q60-Q64 Congenital malformations of the urinary system
0.692 0.308 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.691 0.309 0.000
M60-M63 Disorders of muscles
0.691 0.309 0.000
M00-M03 Infectious arthropathies
0.691 0.309 0.000
Z42 Follow-up care involving plastic surgery
0.690 0.310 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.689 0.311 0.000
Z85.6 Personal history of leukaemia
0.689 0.311 0.000
S09 Other and unspecified injuries of head
0.688 0.312 0.000
R47 Speech disturbances, not elsewhere classified
0.688 0.312 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.688 0.312 0.000
X60-X84 Intentional self-harm
0.687 0.313 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.687 0.313 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.686 0.313 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.685 0.315 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.685 0.315 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.684 0.316 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.684 0.316 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.684 0.316 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.684 0.316 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.684 0.316 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.684 0.316 0.000
T36 Poisoning by systemic antibiotics
0.684 0.316 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.682 0.318 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.681 0.319 0.000
M14 Arthropathies in other diseases classified elsewhere
0.681 0.319 0.000
M12 Other specific arthropathies
0.681 0.319 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.681 0.319 0.000
M08 Juvenile arthritis
0.681 0.319 0.000
Z73 Problems related to life-management difficulty
0.681 0.319 0.000
C34.8 Overlapping lesion of bronchus and lung
0.681 0.319 0.000
C34.2 Middle lobe, bronchus or lung
0.681 0.319 0.000
C50-C50 Malignant neoplasm of breast
0.680 0.319 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.680 0.320 0.000
Z95.3 Presence of xenogenic heart valve
0.680 0.320 0.000
Y59 Other and unspecified vaccines and biological substances
0.679 0.321 0.000
Y58 Bacterial vaccines
0.679 0.321 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.679 0.321 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.679 0.321 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.679 0.321 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.679 0.321 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.679 0.321 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.679 0.321 0.000
Y48 Anaesthetics and therapeutic gases
0.679 0.321 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.679 0.321 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.679 0.321 0.000
G24 Dystonia
0.678 0.322 0.000
M90 Osteopathies in diseases classified elsewhere
0.678 0.322 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.678 0.322 0.000
D06 Carcinoma in situ of cervix uteri
0.677 0.322 0.000
G70-G73 Diseases of myoneural junction and muscle
0.677 0.322 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.677 0.323 0.000
E40-E46 Malnutrition
0.676 0.324 0.000
E84 Cystic fibrosis
0.674 0.325 0.000
E79 Disorders of purine and pyrimidine metabolism
0.674 0.325 0.000
E77 Disorders of glycoprotein metabolism
0.674 0.325 0.000
E76 Disorders of glycosaminoglycan metabolism
0.674 0.325 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.674 0.325 0.000
E74 Other disorders of carbohydrate metabolism
0.674 0.325 0.000
E73 Lactose intolerance
0.674 0.325 0.000
E72 Other disorders of amino-acid metabolism
0.674 0.325 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.674 0.325 0.000
E70 Disorders of aromatic amino-acid metabolism
0.674 0.325 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.674 0.325 0.000
Z54 Convalescence
0.674 0.326 0.000
Z80 Family history of malignant neoplasm
0.674 0.326 0.000
T87 Complications peculiar to reattachment and amputation
0.674 0.326 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.673 0.327 0.000
S00.8 Superficial injury of other parts of head
0.672 0.328 0.000
T81.9 Unspecified complication of procedure
0.672 0.328 0.000
R30 Pain associated with micturition
0.671 0.328 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.671 0.328 0.000
M93 Other osteochondropathies
0.671 0.329 0.000
Z90.3 Acquired absence of part of stomach
0.670 0.330 0.000
A49.3 Mycoplasma infection, unspecified
0.668 0.332 0.000
A49.2 Haemophilus influenzae infection, unspecified
0.668 0.332 0.000
R32 Unspecified urinary incontinence
0.668 0.332 0.000
C79.6 Secondary malignant neoplasm of ovary
0.666 0.333 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.666 0.333 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.666 0.333 0.000
Z46.6 Fitting and adjustment of urinary device
0.666 0.334 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.666 0.334 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.665 0.335 0.000
Z71.2 Person consulting for explanation of investigation findings
0.665 0.335 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.665 0.335 0.000
D73 Diseases of spleen
0.664 0.336 0.000
C53 Malignant neoplasm of cervix uteri
0.664 0.336 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.664 0.336 0.000
Chapter IX Diseases of the circulatory system
0.664 0.336 0.000
Y52 Agents primarily affecting the cardiovascular system
0.662 0.337 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.662 0.338 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.662 0.338 0.000
B27 Infectious mononucleosis
0.661 0.339 0.000
Y43.9 Primarily systemic agent, unspecified
0.661 0.339 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.661 0.339 0.000
Y43.6 Enzymes, not elsewhere classified
0.661 0.339 0.000
Y43.5 Acidifying and alkalising agents
0.661 0.339 0.000
Y43.4 Immunosuppressive agents
0.661 0.339 0.000
Y43.2 Antineoplastic natural products
0.661 0.339 0.000
Y43.1 Antineoplastic antimetabolites
0.661 0.339 0.000
Y43.0 Antiallergic and antiemetic drugs
0.661 0.339 0.000
Q00-Q07 Congenital malformations of the nervous system
0.661 0.339 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.660 0.340 0.000
S62 Fracture at wrist and hand level
0.659 0.341 0.000
H91 Other hearing loss
0.659 0.341 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.658 0.342 0.000
M13.0 Polyarthritis, unspecified
0.657 0.343 0.000
V10-V19 Pedal cyclist injured in transport accident
0.656 0.344 0.000
Z43 Attention to artificial openings
0.655 0.345 0.000
Z94.7 Corneal transplant status
0.655 0.345 0.000
E88 Other metabolic disorders
0.655 0.345 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.655 0.345 0.000
M10 Gout
0.654 0.346 0.000
S92.2 Fracture of other tarsal bone(s)
0.654 0.346 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.653 0.347 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.653 0.347 0.000
S92.00 Fracture of calcaneus (closed)
0.652 0.348 0.000
H60-H62 Diseases of external ear
0.652 0.348 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.652 0.348 0.000
E63 Other nutritional deficiencies
0.652 0.348 0.000
E56 Other vitamin deficiencies
0.652 0.348 0.000
E51 Thiamine deficiency
0.652 0.348 0.000
E50 Vitamin A deficiency
0.652 0.348 0.000
E60 Dietary zinc deficiency
0.652 0.348 0.000
E59 Dietary selenium deficiency
0.652 0.348 0.000
E58 Dietary calcium deficiency
0.652 0.348 0.000
E54 Ascorbic acid deficiency
0.652 0.348 0.000
E52 Niacin deficiency [pellagra]
0.652 0.348 0.000
S99 Other and unspecified injuries of ankle and foot
0.651 0.348 0.000
S98 Traumatic amputation of ankle and foot
0.651 0.348 0.000
S97 Crushing injury of ankle and foot
0.651 0.348 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.651 0.348 0.000
S95 Injury of blood vessels at ankle and foot level
0.651 0.348 0.000
S94 Injury of nerves at ankle and foot level
0.651 0.348 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.651 0.348 0.000
Q50-Q56 Congenital malformations of genital organs
0.651 0.349 0.000
Z75 Problems related to medical facilities and other health care
0.651 0.349 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.650 0.350 0.000
Z76 Persons encountering health services in other circumstances
0.650 0.350 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.650 0.350 0.000
M81 Osteoporosis without pathological fracture
0.650 0.350 0.000
Y57 Other and unspecified drugs and medicaments
0.649 0.351 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.648 0.352 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.648 0.352 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.648 0.352 0.000
B35-B49 Mycoses
0.648 0.352 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.648 0.352 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.647 0.353 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.647 0.353 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.646 0.354 0.000
G60 Hereditary and idiopathic neuropathy
0.646 0.354 0.000
G64 Other disorders of peripheral nervous system
0.646 0.354 0.000
E87.4 Mixed disorder of acid-base balance
0.646 0.354 0.000
E87.3 Alkalosis
0.646 0.354 0.000
R23 Other skin changes
0.645 0.355 0.000
S01.0 Open wound of scalp
0.645 0.355 0.000
D60-D64 Aplastic and other anaemias
0.644 0.356 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.644 0.356 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.642 0.358 0.000
I30-I52 Other forms of heart disease
0.640 0.360 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.639 0.361 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.639 0.361 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.639 0.361 0.000
Q35-Q37 Cleft lip and cleft palate
0.639 0.361 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.639 0.361 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.639 0.361 0.000
S68 Traumatic amputation of wrist and hand
0.639 0.361 0.000
E83.4 Disorders of magnesium metabolism
0.639 0.361 0.000
Z92.0 Personal history of contraception
0.638 0.362 0.000
D75 Other diseases of blood and blood-forming organs
0.638 0.362 0.000
S91 Open wound of ankle and foot
0.638 0.362 0.000
S70-S79 Injuries to the hip and thigh
0.638 0.362 0.000
Z83 Family history of other specific disorders
0.637 0.363 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.637 0.363 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.636 0.363 0.000
S00.7 Multiple superficial injuries of head
0.636 0.364 0.000
S00.5 Superficial injury of lip and oral cavity
0.636 0.364 0.000
S00.4 Superficial injury of ear
0.636 0.364 0.000
S00.3 Superficial injury of nose
0.636 0.364 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.636 0.364 0.000
S00.1 Contusion of eyelid and periocular area
0.636 0.364 0.000
C71.3 Parietal lobe
0.636 0.364 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.635 0.365 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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